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GPI Biosynthesis Report< | |
| GPI Biosynthesis Main Page | GPI Site Motif | GPI Site Prediction | Home Page B.E. |
| Molecular Function: | Mannosyltransferase IV (MT IV) |
|---|---|
| Complex: | - |
| Cellular Localization: | ER membrane, ER lumen |
| Domain Architecture: | N --|TM|-----globular Domain-----|multiple TM regions|-- C |
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Orthologues |  |
|---|
| Protein | Organism | Sequence Length | GenBank Entry |
| orf6.6626.prot | Candida albicans | 498 | |
| AAF47201.1 | Drosophila melanogaster | 830 | gi|7291781| |
| NP_079439.1 | Homo sapiens | 579 | gi|13376765| |
| SMP3_YEAST | Saccharomyces cerevisiae | 516 | gi|2507131| |
| YADC_SCHPO | Schizosaccharomyces pombe | 533 | gi|1351602| |
Fasta-File of the Family-Members
| Alignments SMP3: |
- MView - Clustal |
|---|---|
| PIG-M, PIG-B, SMP3 |
- Alignment MView - Alignment Clustal - Tree |
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Literature | |
|---|
| PubMed: 11356840 | The essential Smp3 protein is required for addition of the side-branching fourth mannose during assembly of yeast glycosylphosphatidylinositols. J Biol Chem 2001 Jul 20;276(29):27731-9 |
| PubMed: 11102867 | Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis. Curr Opin Chem Biol 2000 Dec;4(6):632-8 |
Author: Birgit.Eisenhaber@nt.imp.univie.ac.at on internet.