MyristoylCoA:Protein N-Myristoyltransferase
Supplementary material to
N-terminal N-Myristoylation of Proteins:
I. Refinement of the Sequence Motif and its Taxon-specific Differences
II. Prediction of Substrate Proteins from Amino Acid Sequence
The following search results are accessible via HTML-pages:
PSI-BLAST (nr) 50 hits (related taxonomy report)
TBLASTN (nr) 70 hits (related taxonomy report)
TBLASTN (est) 525 hits (related taxonomy report)
TBLASTN (gss) 39 hits (related taxonomy report)
TBLASTN (htgs) 35 hits (related taxonomy report)
We provide the alignment of the NMTs in NR database (including 2 potential NMT homologues from entomopoxviri) and further below a complete alignment (including ESTs) of sequences homologous to experimentally characterized NMTs from 64 different organisms.
Alignment of the 21 NMT homologues in nr-database plus the two viral sequences:
Alignment of sequences from 64 organisms (including putative NMTs from ESTs):
Alignments were generated with ClustalX (Thompson et al. 1997; Matrix: Gonnet, Gap open penalty: 10, Gap extension penalty: 0.2).
Accession numbers of the sequences:
Saccharomyces cerevisiae NR
P14743
Candida albicans NR P30418
Candida glabrata NR O74234
Schizosaccharomyces pombe NR
O43010
Cryptococcus neoformans NR
P34809
Histoplasma capsulatum NR
P34763
Aspergillus fumigatus NR Q9UVX3
Arabidopsis thaliana1 NR
AAF60968
Arabidopsis thaliana2 NR
AAK49038
Leishmania major NR AAG38102
Plasmodium falciparum NR AAF18461
Drosophila melanogaster NR AAD27855
Caenorhabditis elegans NR
P46548
Bos taurus1 NR P31717
Bos taurus2 NR Q9N181
Mus musculus2 NR O70311
Homo sapiens2 NR O60551
Mus musculus1 NR O70310
Homo sapiens1 NR P30419
Brassica oleracea NR AAF19802
Guillardia theta NR NP_113498
Amsacta moorei entomopoxvirus
NR AAG02925
Melanoplus sanguinipes
entomopoxvirus NR NP_048143
Giardia intestinalis HTGS
AC075683(+1) AC041267(+3) AC088637(+1)
Saccharomyces klyveri GSS
AZ124646(+2)
Trypanosoma brucei GSS
AL490833(-3)
Trypanosoma cruzi GSS/EST
AZ051049(+1) AI069625(+3)
Tetraodon nigroviridis GSS
AL166863(+3) AL170798(+2) AL186230(-3) AL319620(-2) AL319620(-3)
Saccharomyces servazzi GSS
AL404522(+3)
Saccharomyces unisporus GSS
AZ930605(+1)
Entamoeba histolytica GSS
AZ672640(-3) AZ685745(+1)
Plasmodium vivax GSS
AZ572682(-3)
Plasmodium berghei GSS
AZ526668(+3) AZ525157(-1)
Danio rerio EST AW134126(+3)
AI444250(+2) AI657581(+2) AI878266(+2)
Pleuronectes americanus EST
AW013694(+1)
Sus scrofa EST F14725(+1)
Pneumocystis carinii EST
AW334395(-1)
Aspergillus nidulans EST
AI211114(+3)
Schistosoma mansoni EST
AW017038(+2)
Rattus norvegicus EST
BE126380(+3) C06728(+3) BF522952(+2) AI501085(-1)
Strongyloides stercoralis EST
BE580365(+3)
Rattus sp EST AW141187(+1)
Meloidogyne javanica EST
BG737070(+3)
Ciona intestinalis EST
AV671484(+2) AV671935(+2) AV676318(-1)
Bombyx mori EST AV403090(+3)
Aspergillus niger EST
BE759691(+1)
Triticum aestivum EST
BE402458(+2) BE606254(+3) BE418143(+2)
Gallus gallus EST BG711647(+2)
Glycine max EST AW132453(+2)
BF069724(+3) BF070843(+1)
Xenopus laevis EST AW645003(+1)
BE026066(+3) AW766461(-1)
Medicago truncatula EST
BF648024(+3) AW586887(+3)
Phytophthora infestans EST
BE776171(+3)
Ceratopteris richardii EST
BE641641(+3)
Pinus taeda EST AW982000(+2)
AW290567(+1) AW888213(+3)
Oryza sativa HTGS AP003273(-1)
Zea mays EST BE644280(+1)
Sorghum propinquum EST
BF481036(+2)
Hordeum vulgare EST
BE194349(+2)
Dictyostelium discoideum EST
AU060092(+2) AU034531(+3)
Gossypium hirsutum EST
AI726036(+2)
Solanum tuberosum EST
BE471614(+2) BG350597(+2)
Beta vulgaris EST BI095908(+2)
Lycopersicon esculentum EST
AW649554(+3) AW224043(+2) AI897548(+1) AW036027(+1) AW037713(+3)
Lotus japonicus EST
AV409858(+1) AV423721(+3)
Mesembryanthemum crystallinum
EST BE131169(-3)
Gossypium arboreum EST
BF278989(+1) BF279264(+2) BG446339(+2)
Populus tremula EST
BI069814(+1)
Sorghum bicolor EST
BG465115(+2)
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