
| SAG1_YEAST | 3.17 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.35 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.13 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.56 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.20 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.61 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -2.35 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.18 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.14 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AGA1_YEAST | 8.21 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.82 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.86 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.97 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.27 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.49 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CWP1_YEAST | 14.35 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.41 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.06 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| CWP2_YEAST | 17.62 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.86 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.88 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| FLO1_YEAST | 10.37 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.34 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.87 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.09 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CW14_YEAST | 14.64 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.59 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.24 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.50 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.13 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.08 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| TIP1_YEAST | 19.62 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.05 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.13 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| TIR1_YEAST | 16.92 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.71 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.41 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| SED1_YEAST | 17.48 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.28 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.45 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.26 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.05 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| FIG2_YEAST | 10.23 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.61 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.71 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.14 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -2.24 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.29 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| KRE1_YEAST | -2.39 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.30 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.12 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -4.41 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -3.39 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.78 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.97 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| GAS1_YEAST | 13.74 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.09 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -2.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.31 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.08 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YAP3_YEAST | 0.65 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.90 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -4.79 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.53 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.70 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.21 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| S61146 | -4.65 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 5.62 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | -4.00 |
| Function 3 = Sum : volume function [-1..2] | -3.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.52 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.78 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.43 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.01 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.20 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YIV9_YEAST | 11.02 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.80 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.50 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.46 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.15 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.37 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| PLB1_YEAST | 9.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.83 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.08 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.80 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.24 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.54 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YJH8_YEAST | 12.67 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.09 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.33 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.35 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.61 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| EGT2_YEAST | 16.28 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.67 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.31 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| DAN4_YEAST | 16.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.18 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.15 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.09 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| PST1_YEAST | 14.38 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.03 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.95 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.37 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.50 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YDR134c; | 17.25 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.52 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.27 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| S69589; | 18.55 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.84 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.29 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| UTR2_YEAST | 15.97 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.55 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.15 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YEY0_YEAST | 19.01 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.06 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.15 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YG46_YEAST | 12.28 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.84 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.50 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YJR1_YEAST | -16.54 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 0.23 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.14 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.03 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.06 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.04 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.93 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | -12.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.90 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.24 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CAA97571.1 | 5.39 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.08 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.21 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.15 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.03 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.52 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.68 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CW12_YEAST | 17.75 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.02 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.26 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| GAS3_YEAST | 16.14 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.19 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YNT0_YEAST | 13.41 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.85 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.61 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YN40_YEAST | 14.27 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.37 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.68 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.41 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| CAA99197.1 | 16.51 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.83 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.95 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| CAA99430.1 | 12.77 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.19 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.15 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.14 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.06 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CAA99714.1 | 21.12 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 21.12 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| S69054 | 11.69 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.46 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.26 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| MKC7_YEAST | 7.81 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.99 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.02 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.11 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -3.45 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.59 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CAR9_CANAL | 13.68 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.80 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.11 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| BAC00849.1 | 10.47 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.24 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.77 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAF66711.2 | 14.93 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.05 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.10 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| DAN1_YEAST | 19.49 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.43 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.05 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| HYR1_CANAL | 15.15 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.52 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.40 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.23 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.03 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.62 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| EPD1_CANMA | 16.03 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.48 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.86 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.76 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.28 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.56 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| EPD2_CANMA | 8.01 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.83 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.55 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.20 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.63 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.44 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YAG3_YEAST | 10.37 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.34 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.87 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.09 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| PHR1_CANAL | 14.53 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.84 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.08 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.07 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.16 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| PHR2_CANAL | 15.34 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.17 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.86 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.02 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.39 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.56 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AMYH_YEAST | 10.57 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.57 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.86 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.14 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| SPS2_YEAST | 8.64 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.12 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.12 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.44 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.66 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.21 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| EC33_YEAST | 17.51 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.48 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.19 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.73 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.05 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NP_015028 | 19.29 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.65 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.05 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.31 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| S64867 | 13.28 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.67 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.50 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.49 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.26 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.09 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NP_013719 | 16.39 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.44 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.03 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NP_012254 | 18.47 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.43 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.82 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.08 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.06 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NP_014612 | 11.50 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.52 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.19 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.64 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.10 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.04 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NP_013295 | 17.30 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.55 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.08 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.06 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NP_014509 | 1.67 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 10.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -3.57 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.65 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.16 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.96 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAN64312 | 16.60 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.61 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAL47843 | 15.52 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.43 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.48 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.40 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAG29538 | 13.72 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.04 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.87 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.08 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.06 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| HWP1_CANAL | 15.08 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.99 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.14 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.78 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| AAG09787 | 15.31 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.29 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.20 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.78 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| AAG09790 | 13.10 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.19 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.76 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.02 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| AAG09792 | 1.64 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 7.83 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.32 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -2.37 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.18 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.60 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.91 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.75 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.07 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| ALS1_CANAL | 13.09 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.38 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.29 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| ALS3_CANAL | 10.31 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.91 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.48 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.12 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAL66381 | 17.05 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.16 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.03 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAN87849 | 14.24 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.87 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.37 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.17 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.07 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAC35942 | 8.24 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.75 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | -4.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.49 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.02 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAF40139 | 18.14 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 21.74 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.21 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.38 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.66 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -2.35 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAF40140 | 11.31 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.39 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.15 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.62 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.31 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAL09458 | 6.83 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.70 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.18 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.52 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -2.54 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.62 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| EAA32871 | 13.12 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.33 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.12 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.09 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CAC83344 | 15.14 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.04 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.14 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.85 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.16 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.20 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.17 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CAC83346 | 11.70 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.87 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.05 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.04 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.45 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.22 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.36 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.06 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAG16995 | 13.48 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.99 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.05 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.43 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAG16996 | 15.32 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.15 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.86 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.02 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.39 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.56 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| EAA33812 | 8.89 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.58 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.69 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AAA67766 | 10.71 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.27 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -2.56 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 206 | 12.41 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.94 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.26 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.10 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.06 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.08 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 207 | 12.64 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.93 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -2.19 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.28 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 301 | 18.56 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.63 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.07 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 465 | 13.65 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.00 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.10 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.40 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.19 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.64 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.94 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 532 | 17.75 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.09 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.23 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.02 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| 535 | 19.47 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.53 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.05 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| 575 | 13.67 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.67 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.24 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.09 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.10 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.50 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 876 | 15.60 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.80 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.04 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.03 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.06 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.24 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 893 | 11.77 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.63 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.52 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.04 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.87 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.13 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 968 | 19.06 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.06 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 1671 | 10.24 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.18 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.59 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.27 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 1714 | 12.51 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.14 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.57 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.05 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 1824 | 10.49 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.27 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.22 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.54 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 1911 | 13.98 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.01 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2060 | 18.28 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.45 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.13 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2062 | 19.68 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.68 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| 2108 | -0.88 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 2.31 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.11 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.80 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.49 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.38 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.15 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.25 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2451 | 9.86 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.56 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.44 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.09 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.66 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.01 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.41 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2683 | 2.24 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.19 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.44 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.14 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.85 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -4.62 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.96 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.54 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2706 | 17.94 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.36 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.25 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2765 | 14.97 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.10 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.33 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.79 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| 2767 | 16.78 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.04 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.26 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| 2833 | 16.95 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.14 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.19 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2878 | 16.74 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.92 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.10 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.07 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2906 | 13.98 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.52 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.46 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.08 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2907 | 3.80 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.15 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.05 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | -4.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.05 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.12 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.10 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 2952 | 17.58 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.70 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.04 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.06 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3279 | 0.90 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 5.13 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.72 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.45 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.14 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.88 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3380 | 12.32 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.32 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.23 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.28 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.08 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.40 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3618 | 14.02 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.06 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.21 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.81 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3638 | 5.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.15 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.13 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.12 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.95 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -3.04 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.02 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3738 | 7.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 10.18 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.49 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.25 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.43 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.15 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3740 | 17.91 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.01 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.03 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3895 | 12.44 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.40 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.07 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.91 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.89 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.07 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3923 | 15.43 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.46 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.24 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.19 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3966 | 7.83 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.82 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.27 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.08 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -1.06 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.57 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 3989 | 5.60 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.39 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.45 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.18 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.24 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.70 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.19 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 4035 | 12.37 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.38 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.37 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.27 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.13 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.23 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| 4255 | 17.91 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.00 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 4361 | 13.91 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.29 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.12 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.40 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.19 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.64 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.94 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 4404 | 6.56 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.66 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.13 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.84 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.10 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 4652 | 10.17 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.05 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.62 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.58 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.22 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.45 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 4653 | 7.40 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.99 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.91 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.97 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.06 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.01 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.62 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 4654 | 8.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.21 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.36 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | -4.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 4689 | 1.04 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 5.96 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -2.77 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.27 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.08 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -1.06 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.46 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.07 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.19 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 5102 | 9.93 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.54 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.38 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.20 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.02 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 5144 | 20.90 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.93 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 5588 | 10.17 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.14 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.03 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.37 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.73 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 5635 | 17.57 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.03 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.32 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.38 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.16 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.57 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 5760 | 16.81 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.86 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.04 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 5762 | 11.58 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.88 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.93 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 6302 | 10.74 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.90 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.52 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.54 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.05 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.34 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 6321 | 16.76 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.74 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.53 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.96 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.22 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 6390 | 4.47 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.12 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.16 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -2.55 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.03 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 6420 | 9.66 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.91 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -3.50 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.62 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.12 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 6594 | 9.46 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.02 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.37 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.63 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.14 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 7030 | 11.38 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.34 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.53 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.42 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| 7130 | 6.12 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 7.73 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.96 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.18 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.13 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.32 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 7414 | 14.56 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.97 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.46 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.75 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.07 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.10 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 7472 | 15.73 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.31 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.06 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.40 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.03 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 7609 | 14.00 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.92 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.37 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.49 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.05 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 8495 | 15.10 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.27 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.03 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.06 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.24 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 8979 | 12.69 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.61 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.02 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.06 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.37 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.47 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 9891 | 10.31 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.91 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.48 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.12 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 9987 | 9.86 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.56 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.44 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.09 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.66 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.01 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.41 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 10273 | 10.80 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.56 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.11 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.08 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.21 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.03 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.05 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.27 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 10397 | 11.06 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.56 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.46 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.40 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.03 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.21 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.17 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.15 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 10424 | 14.04 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.57 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.46 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.08 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 10425 | 11.40 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.67 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.05 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.12 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.10 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 10724 | 5.07 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.41 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.21 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.25 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.66 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.67 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.11 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.44 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 11405 | 15.43 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.46 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.24 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.19 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| 12609 | 20.90 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.93 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU08936.1 | 15.78 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.48 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09072.1 | 17.42 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.12 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.42 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.28 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09099.1 | 17.46 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.98 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.30 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.21 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09117.1 | 11.99 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.10 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.44 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.24 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.42 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09133.1 | 18.01 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.97 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.37 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.06 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09155.1 | 14.85 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.40 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.54 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09175.1 | 16.66 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.92 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.12 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.11 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09263.1 | 16.05 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.62 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.27 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.30 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09568.1 | 17.26 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.95 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.69 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NCU09647.1 | 13.08 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.18 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09729.1 | 6.23 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.40 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.16 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.13 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.42 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.33 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.12 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09733.1 | 16.14 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.14 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09851.1 | 17.71 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.33 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.84 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.78 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09868.1 | 18.85 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.97 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.13 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU09929.1 | 13.11 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.20 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.08 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NCU06381.1 | 12.97 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.86 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.45 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.43 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU06607.1 | 12.56 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.10 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.40 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.18 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.06 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU06703.1 | 14.57 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.63 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.02 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU06781.1 | 17.29 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.36 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.35 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.72 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU07063.1 | 11.39 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.28 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.89 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU07277.1 | 16.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.84 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU07454.1 | 17.86 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.86 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU07485.1 | 15.38 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.67 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.03 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.25 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU07776.1 | 16.70 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.19 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.04 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.42 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.03 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NCU07962.1 | 14.19 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.24 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.12 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.79 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.10 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.03 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU08131.1 | 17.79 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.35 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.20 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU08243.1 | 5.57 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.90 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.89 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -4.43 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU08318.1 | 14.38 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.08 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.19 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.02 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.50 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00086.1 | 10.63 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 10.75 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.08 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00175.1 | 11.06 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.55 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.06 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.57 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.18 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.08 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.91 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.68 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00205.1 | 2.00 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 5.90 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.35 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.19 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.24 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.54 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.57 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00267.1 | 14.22 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.08 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.86 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00270.1 | 13.49 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.63 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.09 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.05 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00322.1 | 11.26 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.05 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.41 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.60 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -2.13 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.10 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.43 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.12 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NCU00473.1 | 18.97 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.32 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.27 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.08 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00881.1 | 11.73 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.58 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.45 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.34 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU00957.1 | 7.94 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.58 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -2.41 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.25 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.54 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.16 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.37 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU01162.1 | 10.11 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.05 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.61 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU01425.1 | 17.95 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.49 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.43 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.11 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU01462.1 | 15.24 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.02 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.73 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU01549.1 | 8.31 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.00 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.04 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -2.07 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -2.47 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU02041.1 | 17.33 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.14 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.43 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.54 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| NCU02184.1 | 15.21 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.51 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.29 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU02584.1 | 12.12 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.22 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.04 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.06 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU02880.1 | 16.70 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.79 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.08 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU02884.1 | 8.32 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.97 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.26 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.14 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.39 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.86 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU02909.1 | 6.70 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 11.03 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.09 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.22 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | -4.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU02956.1 | 14.66 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.84 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.18 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU03168.1 | 12.95 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.89 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.94 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU03222.1 | 11.87 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.81 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -2.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.73 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.24 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.42 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.59 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU03293.1 | 16.85 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.28 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.02 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.41 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU03530.1 | 16.01 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.40 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.24 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.15 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU03602.1 | 11.14 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.45 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.85 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.26 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.18 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU03775.1 | 15.61 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.70 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.08 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.02 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU03873.1 | 14.76 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.19 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.06 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -3.54 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU04066.1 | 8.29 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.50 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.87 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.10 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.03 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.21 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU04493.1 | 17.47 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.53 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.51 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.54 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU04496.1 | 17.78 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.28 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU04543.1 | 10.46 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.61 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.45 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.53 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.70 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.21 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.24 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU04616.1 | 5.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.25 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.48 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -4.44 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -3.48 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU05229.1 | 16.58 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.58 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU05318.1 | 10.93 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.15 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.37 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.88 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.12 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.28 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.75 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU05395.1 | 14.61 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.46 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.40 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | -4.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.11 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.22 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU05667.1 | 17.38 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.39 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| NCU06185.1 | 17.65 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.65 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YCL048W | 13.88 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.12 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.12 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YHR126C | 16.51 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.08 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.56 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YKL046C | 4.02 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.98 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.56 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -7.98 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.22 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.03 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.17 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YKL175W | 8.10 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.13 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.95 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.06 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR121C | 14.79 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.52 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR343W | 1.52 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 6.49 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | -4.00 |
| Function 3 = Sum : volume function [-1..2] | -0.45 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.36 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.15 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YMR122W-A | 9.79 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.57 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -2.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.38 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.44 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YMR200W | 8.17 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.41 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.14 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.52 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.54 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.57 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.42 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YMR238W | 2.63 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.65 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -7.98 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.22 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.77 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.05 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YOL011W | 12.45 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.86 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.42 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.09 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.20 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.09 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.18 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YOL155C | 2.66 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 7.68 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.61 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.73 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.06 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.49 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| BC342.03 | 13.97 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.51 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.07 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.38 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC19B12.02c | 19.75 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.00 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.04 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.20 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC24B10.06 | 14.83 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.78 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.95 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC1223.12c | 11.76 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.18 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.17 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | -4.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.24 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC19G12.16c | 14.09 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.09 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC1795.09 | 11.07 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.53 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -2.58 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.56 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC17A5.04c | 11.24 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.54 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.27 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.37 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.04 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.60 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC1742.01 | 14.27 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.62 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.19 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.04 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| BC215.13 | 19.44 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.78 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.34 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC11E3.13c | 20.40 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.79 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.04 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.01 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.15 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.15 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| APB18E9.04c | 15.95 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.04 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC1F8.02c | 18.23 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.58 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.18 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.15 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC750.07c | 5.81 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 10.19 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -2.99 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.39 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.96 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC26A3.01 | 17.27 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.64 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.37 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC27F1.07 | 7.97 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.33 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.10 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.67 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -2.57 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.09 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -2.91 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC553.10 | 20.68 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 21.04 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.34 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| BP19A11.02c | 18.13 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.63 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.03 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.38 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC27E2.11c | 16.75 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.70 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.91 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.02 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC1322.10 | 14.67 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.45 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.88 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.80 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.10 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC757.12 | 20.63 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.98 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.27 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.04 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| BC1E8.05 | 16.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.52 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.65 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| CC63.02c | 6.39 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.76 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.79 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -6.25 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -2.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.05 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.16 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC1786.02 | 17.16 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.23 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.04 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC1F5.08c | 2.23 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.71 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -4.87 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.50 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.61 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.48 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| BPJ4664.02 | 7.56 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.03 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.86 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.69 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.49 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.39 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| APB15E9.01c | 22.91 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 22.93 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.02 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| AC1705.03c | 22.93 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 22.94 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| GAS1_N506C | 10.36 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.54 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.51 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.19 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.09 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.31 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.08 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

Last modified: 13th August 2003