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GPI Biosynthesis Report< | |
| GPI Biosynthesis Main Page | GPI Site Motif | GPI Site Prediction | Home Page B.E. |
| Molecular Function: | part of the transamidase complex |
|---|---|
| Complex: | GPAA1/GAA1, PIG-K/GPI8, PIG-S/GPI17, PIG-T/GPI16 |
| Cellular Localization: | ER membrane |
| Domain Architecture: | N Signal Peptide--------lumenal part--------|TM|-- C (cytosol) |
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Orthologues |  |
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| Protein | Organism | Sequence Length | GenBank Entry |
| EAA10074.1 | Anopheles gambiae str. PEST | 598 | gi|21297929| |
| NP_566299.1 | Arabidopsis thaliana | 644 | gi|18397852| |
| AN1775.1 | Aspergillus nidulans | 582 | |
| NP_505797.1 | Caenorhabditis elegans | 531 | gi|17559820| |
| orf6.5557.prot | Candida albicans | 535 | |
| AAF46367.1 | Drosophila melanogaster | 633 | gi|7290926| |
| BAB60854 | Homo sapiens | 578 | gi|14456615| |
| CAC34729.1 | Mus musculus | 578 | gi|13399274| |
| XP_325499.1 | Neurospora crassa | 632 | gi|32410037| |
| 19933219 | Oryza sativa | 587 | gi|19933219| |
| NP_012058.1 | Saccharomyces cerevisiae | 610 | gi|6321982| |
| T39499 | Schizosaccharomyces pombe | 545 | gi|7490312| |
Fasta-File of the Family-Members
| Alignments PIG-T: |
- MView - Clustal |
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Literature | |
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| PubMed: 11598210 | The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p. Mol Biol Cell 2001 Oct;12(10):3295-306 |
| PubMed: 11483512 | PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8. EMBO J 2001 Aug 1;20(15):4088-98 |
Author: Birgit.Eisenhaber@nt.imp.univie.ac.at on internet.