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GPI Anchor Biosynthesis Report: GPI7 family

Molecular Function: Phosphoethanolamine Transferase II
Complex: -
Cellular Localization:ER membrane, ER lumen
Domain Architecture:(cytosol) N --|TM|-----globular Domain(s)-----|multiple TM regions|-- C (?)

Protein Organism Sequence Length GenBank Entry
NP_179839.1 Arabidopsis thaliana 897 gi|15227239|
NP_495820.1 Caenorhabditis elegans 795 gi|17533537|
AAF59237.1 Drosophila melanogaster 880 gi|7304201|
NP_012473.1 Saccharomyces cerevisiae 830 gi|6322399|
YA93_SCHPO Schizosaccharomyces pombe 758 gi|1175452|
AAK52677.1 Yarrowia lipolytica 860 gi|14029404|

Fasta-File of the Family-Members

Alignments GPI7: - MView
- Clustal
PIG-N, GPI7, PIG-O - Alignment MView
- Alignment Clustal
- Tree

PubMed: 11746679 Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes.
Proteins 2001 Dec 1;45(4):318-24
PubMed: 10329735 Deletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrity.
J Biol Chem 1999 May 21;274(21):15251-61

Author: on internet.
Last modified: 24th January 2003