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GPI Biosynthesis Report< | |
| GPI Biosynthesis Main Page | GPI Site Motif | GPI Site Prediction | Home Page B.E. |
| Molecular Function: | Phosphoethanolamine Transferase II |
|---|---|
| Complex: | - |
| Cellular Localization: | ER membrane, ER lumen |
| Domain Architecture: | (cytosol) N --|TM|-----globular Domain(s)-----|multiple TM regions|-- C (?) |
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Orthologues |  |
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| Protein | Organism | Sequence Length | GenBank Entry |
| NP_179839.1 | Arabidopsis thaliana | 897 | gi|15227239| |
| NP_495820.1 | Caenorhabditis elegans | 795 | gi|17533537| |
| AAF59237.1 | Drosophila melanogaster | 880 | gi|7304201| |
| NP_012473.1 | Saccharomyces cerevisiae | 830 | gi|6322399| |
| YA93_SCHPO | Schizosaccharomyces pombe | 758 | gi|1175452| |
| AAK52677.1 | Yarrowia lipolytica | 860 | gi|14029404| |
Fasta-File of the Family-Members
| Alignments GPI7: |
- MView - Clustal |
|---|---|
| PIG-N, GPI7, PIG-O |
- Alignment MView - Alignment Clustal - Tree |
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Literature | |
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| PubMed: 11746679 | Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes. Proteins 2001 Dec 1;45(4):318-24 |
| PubMed: 10329735 |
Deletion of GPI7, a yeast gene required for addition of a side chain to the glycosylphosphatidylinositol (GPI) core structure, affects GPI protein transport, remodeling, and cell wall integrity. J Biol Chem 1999 May 21;274(21):15251-61 |
Author: Birgit.Eisenhaber@nt.imp.univie.ac.at on internet.