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GPI Anchor Biosynthesis Report: NP_012473.1 (GPI7 family, Saccharomyces cerevisiae)



Sequence Analysis
Name From To Source/E Description
COG1524: Uncharacterized proteins of the AP superfamily 1 388 COG: E=2e-110  
TM 6 26 toppred2=2.111  
LCR 14 25 SEG 12 2.2 2.5  
cluster 36 65 SAPS Mixed charge cluster
PF01663: Type 1 Phosphodiesterase/ Nucleotide Pyrophosphatase 36 367 Pfam E=1.7  
LCR 37 50 SEG 12 2.2 2.5  
PF00884: Sulfatase 52 423 Pfam E=40  
PF01676: Metalloenzyme Superfamily 180 283 Pfam E=5  
cluster 212 251 SAPS Mixed charge cluster
cluster 241 264 SAPS Negative charge cluster
TM 324 344 toppred2=1.573  
TM 406 426 toppred2=2.468  
LCR 438 453 SEG 12 2.2 2.5  
TM 440 460 toppred2=2.080  
TM 464 484 toppred2=1.567  
TM 530 550 toppred2=1.925  
LCR 618 631 SEG 12 2.2 2.5  
TM 684 704 toppred2=1.003  
TM 725 745 toppred2=1.543  
TM 769 789 toppred2=1.710  
TM 801 821 toppred2=1.199  


Sequence Information
Protein NP_012473.1
Analysis
  • BlastP against nr

  • Output Created by a Suite of Single Sequence Analysis Techniques
  • Protein Description
    SEQ.SOURCE: gi|6322399|gb|NP_012473.1|NP_012473 Local Anesthetics Sensitive: involved in the attachment of glycosylphosphatidylinositol (GPI) anchors to proteins.; Las21p [Saccharomyces cerevisiae].
    Protein Sequence
    MNLKQFTCLS CAQLLAILLF IFAFFPRKIV LTGISKQDPD QDRDLQRDRP FQKLVFVIID
    ALRSDFLFDS QISHFNNVHQ WLNTGEAWGY TSFANPPTVT LPRLKSITTG STPSFIDLLL
    NVAQDIDSND LSEHDSWLQQ FIQHNNTIRF MGDDTWLKLF PQQWFDFADP THSFFVSDFT
    QVDNNVTRNL PGKLFQEWAQ WDVAILHYLG LDHIGHKDGP HSKFMAAKHQ EMDSILKSIY
    DEVLEHEDDD DTLICVLGDH GMNELGNHGG SSAGETSAGL LFLSPKLAQF ARPESQVNYT
    LPINASPDWN FQYLETVQQI DIVPTIAALF GMPIPMNSVG IIIPDFLQLL PNKLASMKEN
    FMHLWKLSDH HGEVALDDFT AEDIYTKMYT IQETLTKSAT NYNYPLLTLA FVGFLIITII
    AIYVLLRYSG PDFWQLRVSS LSVLLVSIIL GVSTFASSFI EEEHQLWWWI VTAFSAVPLF
    VYRLNVLIIV RWFIMMACVR SIKFWNNSGQ KFIYSNVMSN LLNQNPSWKW CLNMLTFLVL
    IMASAGFQVL HFIVTTILVG LCFTYKISWE IVNGNQAEIP LFMHDLLAKI DFAPTESNLI
    VLARVFFQAW AIVVISRLVL TKLKVLNKNY LIKDMKVYIT ILLMFQTSSQ NIGQFLVFQI
    LESQIFYFFQ NIPTASLTST SKIYFSNLVS LILQNFTFFQ FGGTNSISTI DLGNAYHGVS
    SDYNIYVVGI LMSVANFAPA IYWSMLPWSI NYASIPAQVK LQTFIRSKLP AFTYHCIFGT
    CLMTACVVLR FHLFIWSVFS PKLCYFLGWN FVMGLLNGWL PELALLCALD


    Author: Birgit.Eisenhaber@nt.imp.univie.ac.at on internet.
    Last modified: 24th January 2003