Score E
Sequences producing significant alignments: (bits) Value
ref|XP_002185.1| regulator of G-protein signalling 5 [Homo ... 262 1e-69
ref|NP_003608.1| regulator of G-protein signalling 5; Regul... 262 1e-69
ref|NP_033089.1| regulator of G-protein signaling 5 [Mus mu... 236 1e-61
ref|NP_062214.1| regulator of G-protein signaling 5 [Rattus... 235 2e-61
pir||JC7228 G-protein signaling regulator 5 homolog - clawe... 219 1e-56
gb|AAG18443.1|AF300649_1 (AF300649) regulator of G-protein ... 168 3e-41
ref|NP_062217.1| regulator of G-protein signaling 8 [Rattus... 167 6e-41
gb|AAF85981.1|AF279918_1 (AF279918) regulator of G-protein ... 162 2e-39
gb|AAF34625.1|AF215668_1 (AF215668) regulator of G-protein ... 160 7e-39
ref|NP_033087.1| regulator of G-protein signaling 2 [Mus mu... 159 1e-38
ref|NP_005604.1| regulator of G-protein signaling 4; RGP4 [... 159 1e-38
ref|NP_002914.1| regulator of G-protein signalling 2, 24kD;... 159 1e-38
ref|XP_005324.1| regulator of G-protein signalling 3 [Homo ... 159 2e-38
ref|NP_066929.1| regulator of G-protein signalling 3 [Homo ... 159 2e-38
gb|AAF34627.1|AF215670_1 (AF215670) regulator of G-protein ... 158 2e-38
gb|AAF34626.1|AF215669_1 (AF215669) regulator of G-protein ... 158 2e-38
ref|NP_058910.1| regulator of G-protein signaling 4 [Rattus... 158 2e-38
gb|AAF80227.1|AF076642_1 (AF076642) regulator of G-protein ... 156 1e-37
ref|NP_033088.1| regulator of G-protein signaling 4 [Mus mu... 156 1e-37
gb|AAC16913.1| (U70427) mA28-RGS14p [Mus musculus] 153 9e-37
ref|XP_002066.1| regulator of G-protein signalling 16 [Homo... 150 6e-36
sp|O15492|RGSG_HUMAN REGULATOR OF G-PROTEIN SIGNALING 16 (R... 150 6e-36
ref|NP_002919.1| regulator of G-protein signalling 16; Regu... 150 6e-36
gb|AAF70201.1|AF263451_1 (AF263451) RGS4 protein [Xenopus l... 150 8e-36
sp|P97428|RGSG_MOUSE REGULATOR OF G-PROTEIN SIGNALING 16 (R... 150 8e-36
sp|P56700|RGSG_RAT REGULATOR OF G-PROTEIN SIGNALING 16 (RGS... 148 2e-35
sp|O46471|RGSG_BOVIN REGULATOR OF G-PROTEIN SIGNALING 16 (R... 146 9e-35
ref|NP_056626.1| regulator of G-protein signaling 1 [Mus mu... 135 2e-31
ref|XP_001330.1| regulator of G-protein signalling 1 [Homo ... 134 4e-31
ref|NP_002913.1| regulator of G-protein signalling 1; Regul... 133 7e-31
sp|O14921|RGSD_HUMAN REGULATOR OF G-PROTEIN SIGNALING 13 (R... 130 8e-30
gb|AAF57785.1| (AE003802) EG:52C10.2 gene product [Drosophi... 125 2e-28
sp|P49800|RGS5_RAT REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5... 124 3e-28
gb|AAD53050.1| (AF139872) regulator of G-protein signalling... 123 1e-27
gb|AAD45947.1|AF151967_1 (AF151967) RGS protein Gz-GAP [Gal... 121 4e-27
sp|P79348|RGSX_BOVIN RETINA SPECIFIC REGULATOR OF G-PROTEIN... 121 4e-27
gb|AAD45948.1|AF151968_1 (AF151968) RGS protein RGS-17 [Gal... 120 5e-27
ref|NP_003693.1| regulator of Gz-selective protein signalin... 119 1e-26
pir||T13580 hypothetical protein 52C10.2 - fruit fly (Droso... 119 2e-26
ref|NP_064342.1| regulator of G-protein signaling 17; regul... 118 3e-26
gb|AAF05757.1|AF191554_1 (AF191554) regulator of G-protein ... 117 4e-26
ref|NP_067349.1| regulator of G-protein signaling Z1 [Mus m... 117 4e-26
ref|XP_004378.1| regulator of G-protein signalling 17 [Homo... 116 8e-26
ref|NP_036551.2| regulator of G-protein signalling 17 [Homo... 116 8e-26
emb|CAB65995.1| (AL080276) dJ101K10.2 (regulator of G-prote... 116 8e-26
gb|AAF33236.1|AF220159_1 (AF220159) RGS-1 [Caenorhabditis e... 115 3e-25
sp|P34295|YKO7_CAEEL HYPOTHETICAL 29.5 KD PROTEIN C05B5.7 I... 115 3e-25
pir||S43576 C05B5.7 protein (clone C05B5) - Caenorhabditis ... 115 3e-25
pir||T21035 hypothetical protein F16H9.1b - Caenorhabditis ... 113 7e-25
sp|P49808|YUE1_CAEEL HYPOTHETICAL 19.6 KDA PROTEIN F16H9.1 ... 113 7e-25
>ref|XP_002185.1| regulator of G-protein signalling 5 [Homo sapiens]
Length = 157
Score = 262 bits (663), Expect = 1e-69
Identities = 129/130 (99%), Positives = 130/130 (99%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
+TSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE
Sbjct: 28 KTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 87
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV
Sbjct: 88 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 147
Query: 129 RSEFYQELIK 138
RSEFYQELIK
Sbjct: 148 RSEFYQELIK 157
>ref|NP_003608.1| regulator of G-protein signalling 5; Regulator of G protein
signaling-5 [Homo sapiens]
sp|O15539|RGS5_HUMAN REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5)
dbj|BAA22889.1| (AB008109) RGS5 [Homo sapiens]
gb|AAB84001.1| (AF030108) RGS5 [Homo sapiens]
gb|AAD40957.1|AF159570_1 (AF159570) regulator of G-protein signalling 5 [Homo sapiens]
Length = 181
Score = 262 bits (663), Expect = 1e-69
Identities = 129/130 (99%), Positives = 130/130 (99%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
+TSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE
Sbjct: 52 KTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 111
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV
Sbjct: 112 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 171
Query: 129 RSEFYQELIK 138
RSEFYQELIK
Sbjct: 172 RSEFYQELIK 181
>ref|NP_033089.1| regulator of G-protein signaling 5 [Mus musculus]
sp|O08850|RGS5_MOUSE REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5)
gb|AAB50618.1| (U67188) G protein signaling regulator RGS5 [Mus musculus]
Length = 181
Score = 236 bits (595), Expect = 1e-61
Identities = 114/130 (87%), Positives = 123/130 (93%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
+ SL+E LQWR SLDKLLQN+YG A+FKSFLKSEFSEENLEFW+ACE+YKKIKSP KMAE
Sbjct: 52 KPSLEEVLQWRQSLDKLLQNSYGFATFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAE 111
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPS SFD+AQKRI+ALMEKDSLPRFV
Sbjct: 112 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPRSFDLAQKRIYALMEKDSLPRFV 171
Query: 129 RSEFYQELIK 138
RSEFY+ELIK
Sbjct: 172 RSEFYKELIK 181
>ref|NP_062214.1| regulator of G-protein signaling 5 [Rattus norvegicus]
gb|AAF73424.1|AF241259_1 (AF241259) RGS5 [Rattus norvegicus]
Length = 181
Score = 235 bits (593), Expect = 2e-61
Identities = 114/129 (88%), Positives = 122/129 (94%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
+ SL+E LQWR SLDKLLQ+NYG ASFKSFLKSEFSEENLEFW+ACE+YKKIKSP KMAE
Sbjct: 52 KPSLEEVLQWRQSLDKLLQSNYGFASFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAE 111
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPS SFD+AQKRI+ALMEKDSLPRFV
Sbjct: 112 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPHSFDLAQKRIYALMEKDSLPRFV 171
Query: 129 RSEFYQELI 137
RSEFY+ELI
Sbjct: 172 RSEFYKELI 180
>pir||JC7228 G-protein signaling regulator 5 homolog - clawed frog
Length = 181
Score = 219 bits (552), Expect = 1e-56
Identities = 104/136 (76%), Positives = 122/136 (89%)
Query: 3 RSPLVIRTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKS 62
+ P + S +EA QWRDSL+KLL+N+YGL+ F+SFLKSEFSEEN+EFW+ACEDYKK KS
Sbjct: 46 KPPKASKPSAEEAGQWRDSLEKLLENSYGLSVFQSFLKSEFSEENIEFWMACEDYKKAKS 105
Query: 63 PAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKD 122
P+KM KAK+IYEEFIQTEAP+EVNIDHFTK +TMKNLVEPS +SF++AQK+I ALMEKD
Sbjct: 106 PSKMTTKAKKIYEEFIQTEAPREVNIDHFTKAVTMKNLVEPSSASFELAQKKIFALMEKD 165
Query: 123 SLPRFVRSEFYQELIK 138
SLPRFVRSEFYQELIK
Sbjct: 166 SLPRFVRSEFYQELIK 181
>gb|AAG18443.1|AF300649_1 (AF300649) regulator of G-protein signaling [Homo sapiens]
Length = 180
Score = 168 bits (421), Expect = 3e-41
Identities = 75/129 (58%), Positives = 103/129 (79%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R S +EA +W DS D LL + YG+A+F++FLK+EFSEENLEFW+ACE++KK +S AK+
Sbjct: 44 RLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVS 103
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KA +I+EEF+ +AP+EVNID T++ T KNL EPSL+ FD AQ ++H+LMEKDS PRF+
Sbjct: 104 KAHRIFEEFVDVQAPREVNIDFQTREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFL 163
Query: 129 RSEFYQELI 137
RS+ Y +L+
Sbjct: 164 RSKMYLDLL 172
>ref|NP_062217.1| regulator of G-protein signaling 8 [Rattus norvegicus]
sp|P49804|RGS8_RAT REGULATOR OF G-PROTEIN SIGNALING 8 (RGS8)
dbj|BAA23680.1| (AB006013) RGS8 [Rattus norvegicus]
Length = 180
Score = 167 bits (418), Expect = 6e-41
Identities = 74/129 (57%), Positives = 103/129 (79%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R S +EA +W DS D LL + YG+A+F++FLK+EFSEENLEFW+ACE++KK +S AK+
Sbjct: 44 RLSTEEATRWADSFDVLLSHKYGVAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVT 103
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KA +I+EEF+ +AP+EVNID T++ T KN+ EPSL+ FD AQ ++H+LMEKDS PRF+
Sbjct: 104 KAHRIFEEFVDVQAPREVNIDFQTREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFL 163
Query: 129 RSEFYQELI 137
RS+ Y +L+
Sbjct: 164 RSKMYLDLL 172
>gb|AAF85981.1|AF279918_1 (AF279918) regulator of G-protein signaling protein 2 [Rattus
norvegicus]
Length = 211
Score = 162 bits (405), Expect = 2e-39
Identities = 73/131 (55%), Positives = 102/131 (77%)
Query: 8 IRTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 67
I+ S +EAL W ++ D+LL + YGLA+F++FLKSEF EEN+EFW+ACED+KK KSP K++
Sbjct: 70 IKPSPEEALLWAEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLS 129
Query: 68 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 127
KA++IY +FI+ EAPKE+NID TK + +N+ E + F AQKR+++LME +S PRF
Sbjct: 130 SKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRF 189
Query: 128 VRSEFYQELIK 138
+ SEFYQ+L K
Sbjct: 190 LESEFYQDLCK 200
>gb|AAF34625.1|AF215668_1 (AF215668) regulator of G-protein signaling 2 [Mus musculus]
Length = 211
Score = 160 bits (400), Expect = 7e-39
Identities = 72/131 (54%), Positives = 101/131 (76%)
Query: 8 IRTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 67
I+ S +EA W ++ D+LL + YGLA+F++FLKSEF EEN+EFW+ACED+KK KSP K++
Sbjct: 70 IKPSPEEAQLWAEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLS 129
Query: 68 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 127
KA++IY +FI+ EAPKE+NID TK + +N+ E + F AQKR+++LME +S PRF
Sbjct: 130 SKARKIYTDFIEKEAPKEINIDFQTKSLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRF 189
Query: 128 VRSEFYQELIK 138
+ SEFYQ+L K
Sbjct: 190 LESEFYQDLCK 200
>ref|NP_033087.1| regulator of G-protein signaling 2 [Mus musculus]
sp|O08849|RGS2_MOUSE REGULATOR OF G-PROTEIN SIGNALING 2 (RGS2)
gb|AAB50617.1| (U67187) G protein signaling regulator RGS2 [Mus musculus]
Length = 211
Score = 159 bits (399), Expect = 1e-38
Identities = 72/131 (54%), Positives = 101/131 (76%)
Query: 8 IRTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 67
I+ S +EA W ++ D+LL + YGLA+F++FLKSEF EEN+EFW+ACED+KK KSP K++
Sbjct: 70 IKPSPEEAHVWAEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLS 129
Query: 68 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 127
KA++IY +FI+ EAPKE+NID TK + +N+ E + F AQKR+++LME +S PRF
Sbjct: 130 SKARKIYTDFIEKEAPKEINIDFQTKSLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRF 189
Query: 128 VRSEFYQELIK 138
+ SEFYQ+L K
Sbjct: 190 LESEFYQDLCK 200
>ref|NP_005604.1| regulator of G-protein signaling 4; RGP4 [Homo sapiens]
sp|P49798|RGS4_HUMAN REGULATOR OF G-PROTEIN SIGNALING 4 (RGS4) (RGP4)
pir||S78221 G-protein signaling regulator RGP4 - human
gb|AAC50395.1| (U27768) RGP4 [Homo sapiens]
prf||2206475C G protein signaling regulator [Homo sapiens]
Length = 205
Score = 159 bits (399), Expect = 1e-38
Identities = 71/129 (55%), Positives = 103/129 (79%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R S +E +W +SL+ L+ + GLA+FK+FLKSE+SEEN++FWI+CE+YKKIKSP+K++
Sbjct: 50 RVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSP 109
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAK+IY EFI +A KEVN+D T++ T +N++EP+++ FD AQK+I LMEKDS RF+
Sbjct: 110 KAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFL 169
Query: 129 RSEFYQELI 137
+S FY +L+
Sbjct: 170 KSRFYLDLV 178
>ref|NP_002914.1| regulator of G-protein signalling 2, 24kD; G0 to G1 switch
regulatory 8, 24kD [Homo sapiens]
ref|XP_001898.1| regulator of G-protein signalling 2, 24kD [Homo sapiens]
sp|P41220|RGS2_HUMAN REGULATOR OF G-PROTEIN SIGNALING 2 (RGS2) (G0/G1 SWITCH REGULATORY
PROTEIN 8)
pir||I53020 G-0/G-1 switch regulatory protein 8 - human
gb|AAA20680.1| (L13391) helix-loop-helix phosphoprotein [Homo sapiens]
gb|AAC37587.1| (L13463) helix-loop-helix phosphoprotein [Homo sapiens]
emb|CAB62512.1| (AL035407) dJ419C19.2 (regulator of G-protein signalling 2, 24kD)
[Homo sapiens]
Length = 211
Score = 159 bits (399), Expect = 1e-38
Identities = 72/131 (54%), Positives = 101/131 (76%)
Query: 8 IRTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 67
I+ S +EA W ++ D+LL + YGLA+F++FLKSEF EEN+EFW+ACED+KK KSP K++
Sbjct: 70 IKPSPEEAQLWSEAFDELLASKYGLAAFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLS 129
Query: 68 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 127
KA++IY +FI+ EAPKE+NID TK + +N+ E + F AQKR+++LME +S PRF
Sbjct: 130 SKARKIYTDFIEKEAPKEINIDFQTKTLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRF 189
Query: 128 VRSEFYQELIK 138
+ SEFYQ+L K
Sbjct: 190 LESEFYQDLCK 200
>ref|XP_005324.1| regulator of G-protein signalling 3 [Homo sapiens]
Length = 460
Score = 159 bits (397), Expect = 2e-38
Identities = 74/125 (59%), Positives = 100/125 (79%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
+EAL+W +SL+KLL + YGLA F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+
Sbjct: 327 EEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKK 386
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
I+ E+I +A KEVN+D +T++ T NL + FD+AQKRI LMEKDS PRF+RS+
Sbjct: 387 IFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDL 446
Query: 133 YQELI 137
Y +LI
Sbjct: 447 YLDLI 451
>ref|NP_066929.1| regulator of G-protein signalling 3 [Homo sapiens]
sp|P49796|RGS3_HUMAN REGULATOR OF G-PROTEIN SIGNALING 3 (RGS3) (RGP3)
pir||S78089 G-protein signaling regulator RGS3 - human
gb|AAC50394.1| (U27655) RGP3 [Homo sapiens]
prf||2206475A G protein signaling regulator [Homo sapiens]
Length = 519
Score = 159 bits (397), Expect = 2e-38
Identities = 74/125 (59%), Positives = 100/125 (79%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
+EAL+W +SL+KLL + YGLA F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+
Sbjct: 386 EEALKWGESLEKLLVHKYGLAVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKK 445
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
I+ E+I +A KEVN+D +T++ T NL + FD+AQKRI LMEKDS PRF+RS+
Sbjct: 446 IFAEYIAIQACKEVNLDSYTREHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDL 505
Query: 133 YQELI 137
Y +LI
Sbjct: 506 YLDLI 510
>gb|AAF34627.1|AF215670_1 (AF215670) regulator of G-protein signaling 3 [Mus musculus]
Length = 297
Score = 158 bits (396), Expect = 2e-38
Identities = 74/125 (59%), Positives = 100/125 (79%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
+EAL+W +SL+KLL + YGL F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+
Sbjct: 164 EEALKWSESLEKLLLHKYGLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKK 223
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
I+ EFI +A KEVN+D +T++ T +NL + FD+AQKRI LMEKDS PRF+RS+
Sbjct: 224 IFAEFIAIQACKEVNLDSYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDL 283
Query: 133 YQELI 137
Y +LI
Sbjct: 284 YLDLI 288
>gb|AAF34626.1|AF215669_1 (AF215669) regulator of G-protein signaling 3s [Mus musculus]
Length = 192
Score = 158 bits (396), Expect = 2e-38
Identities = 74/125 (59%), Positives = 100/125 (79%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
+EAL+W +SL+KLL + YGL F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+
Sbjct: 59 EEALKWSESLEKLLLHKYGLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKK 118
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
I+ EFI +A KEVN+D +T++ T +NL + FD+AQKRI LMEKDS PRF+RS+
Sbjct: 119 IFAEFIAIQACKEVNLDSYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDL 178
Query: 133 YQELI 137
Y +LI
Sbjct: 179 YLDLI 183
>ref|NP_058910.1| regulator of G-protein signaling 4 [Rattus norvegicus]
sp|P49799|RGS4_RAT REGULATOR OF G-PROTEIN SIGNALING 4 (RGS4) (RGP4)
pdb|1AGR|E Chain E, Complex Of Alf4-Activated Gi-Alpha-1 With Rgs4
pdb|1AGR|H Chain H, Complex Of Alf4-Activated Gi-Alpha-1 With Rgs4
gb|AAC52440.1| (U27767) RGP4 [Rattus norvegicus]
gb|AAD12065.1| (AF117211) regulator of G-protein signaling 4 [Rattus norvegicus]
prf||2206475B G protein signaling regulator [Rattus norvegicus]
Length = 205
Score = 158 bits (396), Expect = 2e-38
Identities = 71/128 (55%), Positives = 102/128 (79%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R S +E +W +SL+ L+ + GLA+FK+FLKSE+SEEN++FWI+CE+YKKIKSP+K++
Sbjct: 50 RVSQEEVKKWAESLENLINHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSP 109
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAK+IY EFI +A KEVN+D T++ T +N++EP+++ FD AQK+I LMEKDS RF+
Sbjct: 110 KAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFL 169
Query: 129 RSEFYQEL 136
+S FY +L
Sbjct: 170 KSRFYLDL 177
>gb|AAF80227.1|AF076642_1 (AF076642) regulator of G-protein signaling 13 [Homo sapiens]
Length = 235
Score = 156 bits (390), Expect = 1e-37
Identities = 71/130 (54%), Positives = 100/130 (76%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R S +EA++W +S DKLL + GL +F FLK+EFSEEN+EFWIACED+KK K P ++
Sbjct: 74 RVSPEEAVKWGESFDKLLSHRDGLEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHL 133
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAK IYE+FIQT+APKEVN+D TK++ ++ +P+L SFD AQ R++ LME+DS RF+
Sbjct: 134 KAKAIYEKFIQTDAPKEVNLDFHTKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFL 193
Query: 129 RSEFYQELIK 138
+S+ Y +L++
Sbjct: 194 KSDIYLDLME 203
>ref|NP_033088.1| regulator of G-protein signaling 4 [Mus musculus]
sp|O08899|RGS4_MOUSE REGULATOR OF G-PROTEIN SIGNALING 4 (RGS4)
dbj|BAA20400.1| (AB004315) RGS4 [Mus musculus]
Length = 205
Score = 156 bits (390), Expect = 1e-37
Identities = 69/128 (53%), Positives = 102/128 (78%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R S +E +W +SL+ L+ + GLA+FK+FLKSE+SEEN++FWI+CE+YKKIKSP+K++
Sbjct: 50 RVSQEEVKKWAESLENLIHHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSP 109
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
KAK+IY EFI +A KEVN+D T++ T +N+++P+++ FD AQK+I LME+DS RF+
Sbjct: 110 KAKKIYNEFISVQATKEVNLDSCTREETSRNMLQPTITCFDEAQKKIFNLMERDSYRRFL 169
Query: 129 RSEFYQEL 136
+S FY +L
Sbjct: 170 KSRFYLDL 177
>gb|AAC16913.1| (U70427) mA28-RGS14p [Mus musculus]
Length = 202
Score = 153 bits (382), Expect = 9e-37
Identities = 70/128 (54%), Positives = 99/128 (76%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R+ ++ L WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A
Sbjct: 53 RSFSEDVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLAS 112
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
+A QI+EE+I++EAPKEVNIDH T+++T NL + S FD+AQ + LMEKDS PRF+
Sbjct: 113 RAHQIFEEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFL 172
Query: 129 RSEFYQEL 136
+S Y++L
Sbjct: 173 KSPAYRDL 180
>ref|XP_002066.1| regulator of G-protein signalling 16 [Homo sapiens]
Length = 232
Score = 150 bits (375), Expect = 6e-36
Identities = 70/128 (54%), Positives = 96/128 (74%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R ++ L WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A
Sbjct: 83 RNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLAS 142
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
+A QI+EEFI +EAPKEVNIDH T+++T NL + + FD AQ + LMEKDS PRF+
Sbjct: 143 RAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFL 202
Query: 129 RSEFYQEL 136
+S Y++L
Sbjct: 203 KSPAYRDL 210
>sp|O15492|RGSG_HUMAN REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R) (A28-RGS14P)
gb|AAC52040.1| (U94829) retinally abundant regulator of G-protein signaling hRGS-r
[Homo sapiens]
gb|AAC39642.1| (AF009356) regulator of G-protein signaling-16 [Homo sapiens]
Length = 202
Score = 150 bits (375), Expect = 6e-36
Identities = 70/128 (54%), Positives = 96/128 (74%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R ++ L WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A
Sbjct: 53 RNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLAS 112
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
+A QI+EEFI +EAPKEVNIDH T+++T NL + + FD AQ + LMEKDS PRF+
Sbjct: 113 RAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFL 172
Query: 129 RSEFYQEL 136
+S Y++L
Sbjct: 173 KSPAYRDL 180
>ref|NP_002919.1| regulator of G-protein signalling 16; Regulator of G protein
signaling-16 [Homo sapiens]
gb|AAC16912.1| (U70426) A28-RGS14p [Homo sapiens]
Length = 202
Score = 150 bits (375), Expect = 6e-36
Identities = 70/128 (54%), Positives = 96/128 (74%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R ++ L WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A
Sbjct: 53 RNFSEDVLGWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLAS 112
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
+A QI+EEFI +EAPKEVNIDH T+++T NL + + FD AQ + LMEKDS PRF+
Sbjct: 113 RAHQIFEEFICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFL 172
Query: 129 RSEFYQEL 136
+S Y++L
Sbjct: 173 KSPAYRDL 180
>gb|AAF70201.1|AF263451_1 (AF263451) RGS4 protein [Xenopus laevis]
Length = 204
Score = 150 bits (374), Expect = 8e-36
Identities = 66/129 (51%), Positives = 100/129 (77%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R +E +W +SL+ L+ N GLA+F+SFL+SE+SEEN++FW ACE+YKKIK+ A++ E
Sbjct: 49 RVRQEEVKKWAESLENLINNECGLAAFRSFLQSEYSEENIDFWTACENYKKIKTQARLPE 108
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
+A++IYE+FI EA KEVN+D T++ T N+++P+ S+FD AQ +I LMEKDS RF+
Sbjct: 109 QAQKIYEDFISVEATKEVNLDSVTREETSNNILQPTYSTFDEAQHKIFILMEKDSYRRFL 168
Query: 129 RSEFYQELI 137
+S+FY +++
Sbjct: 169 KSKFYLDIV 177
>sp|P97428|RGSG_MOUSE REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R) (A28-RGS14P)
gb|AAC52927.1| (U72881) RGS-r protein [Mus musculus]
gb|AAB50619.1| (U67189) G protein signaling regulator RGS16 [Mus musculus]
gb|AAC53549.1| (U94828) retinally abundant regulator of G-protein signaling mRGS-r
[Mus musculus]
Length = 201
Score = 150 bits (374), Expect = 8e-36
Identities = 68/128 (53%), Positives = 98/128 (76%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R+ ++ L WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A
Sbjct: 52 RSFSEDVLGWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLAS 111
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
+A I++E+I++EAPKEVNIDH T+++T NL + S FD+AQ + LMEKDS PRF+
Sbjct: 112 RAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFL 171
Query: 129 RSEFYQEL 136
+S Y++L
Sbjct: 172 KSPAYRDL 179
>sp|P56700|RGSG_RAT REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R)
Length = 199
Score = 148 bits (370), Expect = 2e-35
Identities = 67/128 (52%), Positives = 97/128 (75%)
Query: 9 RTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAE 68
R+ ++ L WR+S LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A
Sbjct: 52 RSFSEDVLGWRESFQSLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLAS 111
Query: 69 KAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFV 128
+A I++E+I++EAPKEVNIDH T+++T NL + S FD+AQ + LMEKDS PRF+
Sbjct: 112 RAHHIFDEYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFL 171
Query: 129 RSEFYQEL 136
+S Y++L
Sbjct: 172 KSPAYRDL 179
>sp|O46471|RGSG_BOVIN REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R)
gb|AAC99484.1| (AF011361) regulator of G-protein signaling 16/-r [Bos taurus]
Length = 202
Score = 146 bits (365), Expect = 9e-35
Identities = 66/124 (53%), Positives = 95/124 (76%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
++ L W++S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KK++S K+ +A +
Sbjct: 57 EDVLGWKESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKLRSATKLGSRAHR 116
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
I+EEFI +EAPKEVNIDH T+++T NL + FD AQ ++ ALMEKDS PRF++S
Sbjct: 117 IFEEFICSEAPKEVNIDHETRELTRTNLQAATAVCFDAAQWKVRALMEKDSYPRFLKSPA 176
Query: 133 YQEL 136
Y++L
Sbjct: 177 YRDL 180
>ref|NP_056626.1| regulator of G-protein signaling 1 [Mus musculus]
gb|AAF34624.1|AF215667_1 (AF215667) regulator of G-protein signaling 1 [Mus musculus]
Length = 196
Score = 135 bits (336), Expect = 2e-31
Identities = 65/127 (51%), Positives = 90/127 (70%), Gaps = 1/127 (0%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
S +E +QW SL+KLL N G F FLKSEFSEEN+EFW+ACEDYKK ++ + KA
Sbjct: 62 SAEEVMQWSQSLEKLLANQTGQNVFGRFLKSEFSEENIEFWLACEDYKKTETDL-LHNKA 120
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IY+ F+ ++A K++NID T++ T K + P+ +SFD AQK I++LMEKDS PRF++S
Sbjct: 121 ENIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTSFDEAQKVIYSLMEKDSYPRFLKS 180
Query: 131 EFYQELI 137
Y L+
Sbjct: 181 NIYLNLL 187
>ref|XP_001330.1| regulator of G-protein signalling 1 [Homo sapiens]
pir||I56165 B cell activation protein BL34 - human
gb|AAB26289.1| (S59049) BL34=B cell activation gene [human, Peptide, 196 aa] [Homo
sapiens]
Length = 196
Score = 134 bits (334), Expect = 4e-31
Identities = 66/127 (51%), Positives = 90/127 (69%), Gaps = 1/127 (0%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
S E +QW SL+KLL N G F SFLKSEFSEEN+EFW+ACEDYKK +S + KA
Sbjct: 62 SAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDL-LPCKA 120
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
++IY+ F+ ++A K++NID T++ T K + P+ + FD AQK I+ LMEKDS PRF++S
Sbjct: 121 EEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKS 180
Query: 131 EFYQELI 137
+ Y L+
Sbjct: 181 DIYLNLL 187
>ref|NP_002913.1| regulator of G-protein signalling 1; Regulator of G-protein
signaling 1; 1R20 [Homo sapiens]
sp|Q08116|RGS1_HUMAN REGULATOR OF G-PROTEIN SIGNALING 1 (RGS1) (EARLY RESPONSE PROTEIN
1R20) (B-CELL ACTIVATION PROTEIN BL34)
pir||S43436 B cell activation protein BL34 - human
emb|CAA51826.1| (X73427) 1r20 [Homo sapiens]
Length = 196
Score = 133 bits (332), Expect = 7e-31
Identities = 66/127 (51%), Positives = 89/127 (69%), Gaps = 1/127 (0%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
S E +QW SL+KLL N G F SFLKSEFSEEN+EFW+ACEDYKK +S + KA
Sbjct: 62 SAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDL-LPCKA 120
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
++IY+ F+ ++A K++NID T++ T K + P+ + FD AQK I+ LMEKDS PRF++S
Sbjct: 121 EEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKS 180
Query: 131 EFYQELI 137
Y L+
Sbjct: 181 HIYLNLL 187
>sp|O14921|RGSD_HUMAN REGULATOR OF G-PROTEIN SIGNALING 13 (RGS13)
gb|AAB84000.1| (AF030107) RGS13 [Homo sapiens]
Length = 159
Score = 130 bits (323), Expect = 8e-30
Identities = 56/128 (43%), Positives = 91/128 (70%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+E LQW S + L+ YG + ++LK E S+EN++FW+ACE YKKI S +A
Sbjct: 24 TLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRA 83
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
K++Y+ +IQ ++P+E+NID T++ ++N+ EP+ + F+ AQK ++ ME+DS PRF++S
Sbjct: 84 KKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKS 143
Query: 131 EFYQELIK 138
E YQ+L+K
Sbjct: 144 EMYQKLLK 151
>gb|AAF57785.1| (AE003802) EG:52C10.2 gene product [Drosophila melanogaster]
Length = 271
Score = 125 bits (312), Expect = 2e-28
Identities = 57/126 (45%), Positives = 89/126 (70%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+E W S DKL+++ G F++FL+SEFSEEN+ FW+ACED KK SP + EKA
Sbjct: 129 TLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKA 188
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE++I +P+EV++D ++I +N++EP+ +FD AQ +I+ LM +DS PRF+ S
Sbjct: 189 RLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRFLNS 248
Query: 131 EFYQEL 136
+ ++ L
Sbjct: 249 QKFKTL 254
>sp|P49800|RGS5_RAT REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5)
gb|AAC52372.1| (U32435) RGS5 [Rattus norvegicus]
Length = 67
Score = 124 bits (309), Expect = 3e-28
Identities = 60/67 (89%), Positives = 64/67 (94%)
Query: 52 IACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMA 111
+ACE+YKKIKSP KMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPS SFD+A
Sbjct: 1 VACENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPHSFDLA 60
Query: 112 QKRIHAL 118
QKRI+AL
Sbjct: 61 QKRIYAL 67
>gb|AAD53050.1| (AF139872) regulator of G-protein signalling 5 [Sus scrofa]
Length = 67
Score = 123 bits (305), Expect = 1e-27
Identities = 59/67 (88%), Positives = 65/67 (96%)
Query: 52 IACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMA 111
+ACEDYKKIKSP KMAEKAK+IYEEFIQ+EAPKEVNIDHFTK+ITMKNLVEPS SSFD+A
Sbjct: 1 MACEDYKKIKSPVKMAEKAKKIYEEFIQSEAPKEVNIDHFTKEITMKNLVEPSPSSFDVA 60
Query: 112 QKRIHAL 118
QKRI+AL
Sbjct: 61 QKRIYAL 67
>gb|AAD45947.1|AF151967_1 (AF151967) RGS protein Gz-GAP [Gallus gallus]
Length = 218
Score = 121 bits (300), Expect = 4e-27
Identities = 54/128 (42%), Positives = 89/128 (69%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+E W S DKL+ G +F+ FL++EFSEEN+ FW+ACE+ K+ + + + EKA
Sbjct: 82 TLEEVNAWAQSFDKLMLTPAGRNAFREFLRTEFSEENMLFWMACEELKQESNKSVIEEKA 141
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE++I +PKEV++D +++ +N++EPS +FD AQ +I+ LM +DS PRF+ S
Sbjct: 142 RLIYEDYISILSPKEVSLDSRVREVINRNMLEPSQHTFDDAQLQIYTLMHRDSYPRFMNS 201
Query: 131 EFYQELIK 138
Y++L++
Sbjct: 202 AIYKDLLR 209
>sp|P79348|RGSX_BOVIN RETINA SPECIFIC REGULATOR OF G-PROTEIN SIGNALING (RET-RGS1)
gb|AAC48721.1| (U89254) retina specific RGS protein [Bos taurus]
Length = 374
Score = 121 bits (300), Expect = 4e-27
Identities = 56/128 (43%), Positives = 88/128 (68%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+EA W S DKL+ G +F+ FL++EFSEEN+ FW+ACE+ KK + A + EKA
Sbjct: 238 TLEEASAWAQSFDKLMLTPAGRNAFREFLRTEFSEENMLFWMACEELKKEANKATIEEKA 297
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE++I +PKEV++D ++ +++ EPS + FD AQ +I+ LM +DS PRF+ S
Sbjct: 298 RIIYEDYISILSPKEVSLDSRVRETINRSMAEPSRNIFDDAQLQIYTLMHRDSYPRFMNS 357
Query: 131 EFYQELIK 138
Y++L++
Sbjct: 358 ALYKDLLR 365
>gb|AAD45948.1|AF151968_1 (AF151968) RGS protein RGS-17 [Gallus gallus]
Length = 210
Score = 120 bits (299), Expect = 5e-27
Identities = 53/126 (42%), Positives = 87/126 (68%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
DE L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ + EKA+
Sbjct: 76 DEILSWAQNFDKMMKTPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARL 135
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
IYE++I +PKEV++D +++ +NL++PS ++ AQ +I+ LM +DS PRF+ S+
Sbjct: 136 IYEDYISILSPKEVSLDSRVREVINRNLLDPSPHMYEDAQLQIYTLMHRDSFPRFLNSQI 195
Query: 133 YQELIK 138
Y+ L++
Sbjct: 196 YKSLVE 201
>ref|NP_003693.1| regulator of Gz-selective protein signaling [Homo sapiens]
gb|AAC62009.1| (AF060877) Gz-selective GTPase-activating protein [Homo sapiens]
gb|AAC62013.1| (AF074979) regulator of G protein signaling [Homo sapiens]
Length = 217
Score = 119 bits (296), Expect = 1e-26
Identities = 56/128 (43%), Positives = 87/128 (67%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+E W S DKL+ G +F+ FL++EFSEEN+ FW+ACE+ KK + + EKA
Sbjct: 81 TLEEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEANKNIIEEKA 140
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE++I +PKEV++D +++ +N+VEPS FD AQ +I+ LM +DS PRF+ S
Sbjct: 141 RIIYEDYISILSPKEVSLDSRVREVINRNMVEPSQHIFDDAQLQIYTLMHRDSYPRFMNS 200
Query: 131 EFYQELIK 138
Y++L++
Sbjct: 201 AVYKDLLQ 208
>pir||T13580 hypothetical protein 52C10.2 - fruit fly (Drosophila melanogaster)
emb|CAA22951.1| (AL035311) 1-evidence=predicted by
content~1-method=genefinder;084~1-method_score=42.68~1-
evidence_end~2-evidence=predicted by
match~2-match_accession=SWISS-PROT:P49795~2-
match_description=G-ALPHA INTERACTING PROTEIN (GAIP
PROTEIN).~2-match_species=HOM>
Length = 244
Score = 119 bits (295), Expect = 2e-26
Identities = 54/116 (46%), Positives = 82/116 (70%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+E W S DKL+++ G F++FL+SEFSEEN+ FW+ACED KK SP + EKA
Sbjct: 129 TLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVEEKA 188
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPR 126
+ IYE++I +P+EV++D ++I +N++EP+ +FD AQ +I+ LM +DS PR
Sbjct: 189 RLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPR 244
>ref|NP_064342.1| regulator of G-protein signaling 17; regulator of G-protein
signaling Z2 [Mus musculus]
gb|AAF05758.1|AF191555_1 (AF191555) regulator of G-protein signaling Z2 [Mus musculus]
Length = 210
Score = 118 bits (293), Expect = 3e-26
Identities = 51/126 (40%), Positives = 86/126 (67%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
DE L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ + EKA+
Sbjct: 76 DEVLSWSQNFDKMMKTPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKAVEEKARM 135
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
IYE++I +PKEV++D +++ ++L++PS ++ AQ +I+ LM +DS PRF+ S+
Sbjct: 136 IYEDYISILSPKEVSLDSRVREVINRSLLDPSPHMYEDAQLQIYTLMHRDSFPRFLNSQI 195
Query: 133 YQELIK 138
Y+ ++
Sbjct: 196 YKAFVE 201
>gb|AAF05757.1|AF191554_1 (AF191554) regulator of G-protein signaling Z1 [Mus musculus]
Length = 239
Score = 117 bits (291), Expect = 4e-26
Identities = 53/127 (41%), Positives = 86/127 (66%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+E W S D L+ G +F+ FL++EFSEEN+ FW+ACE+ K+ + + + EKA
Sbjct: 103 TLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREANKSTIEEKA 162
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE++I +PKEV++D +++ +N+V+PS FD AQ +I+ LM +DS PRF+ S
Sbjct: 163 RIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQIYTLMHRDSYPRFMNS 222
Query: 131 EFYQELI 137
Y++L+
Sbjct: 223 TVYKDLL 229
>ref|NP_067349.1| regulator of G-protein signaling Z1 [Mus musculus]
gb|AAF05756.1|AF191552_1 (AF191552) regulator of G-protein signaling Z1 [Mus musculus]
Length = 239
Score = 117 bits (291), Expect = 4e-26
Identities = 53/127 (41%), Positives = 86/127 (66%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
+L+E W S D L+ G +F+ FL++EFSEEN+ FW+ACE+ K+ + + + EKA
Sbjct: 103 TLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREANKSTIEEKA 162
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE++I +PKEV++D +++ +N+V+PS FD AQ +I+ LM +DS PRF+ S
Sbjct: 163 RIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQIYTLMHRDSYPRFMNS 222
Query: 131 EFYQELI 137
Y++L+
Sbjct: 223 TVYKDLL 229
>ref|XP_004378.1| regulator of G-protein signalling 17 [Homo sapiens]
Length = 210
Score = 116 bits (289), Expect = 8e-26
Identities = 50/126 (39%), Positives = 86/126 (67%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
+E L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ + EKA+
Sbjct: 76 EEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARM 135
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
IYE++I +PKEV++D +++ +NL++P+ ++ AQ +I+ LM +DS PRF+ S+
Sbjct: 136 IYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQI 195
Query: 133 YQELIK 138
Y+ ++
Sbjct: 196 YKSFVE 201
>ref|NP_036551.2| regulator of G-protein signalling 17 [Homo sapiens]
gb|AAF08978.2|AF202257_1 (AF202257) regulator of G-protein signaling 17 [Homo sapiens]
Length = 208
Score = 116 bits (289), Expect = 8e-26
Identities = 50/126 (39%), Positives = 86/126 (67%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
+E L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ + EKA+
Sbjct: 76 EEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARM 135
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
IYE++I +PKEV++D +++ +NL++P+ ++ AQ +I+ LM +DS PRF+ S+
Sbjct: 136 IYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQI 195
Query: 133 YQELIK 138
Y+ ++
Sbjct: 196 YKSFVE 201
>emb|CAB65995.1| (AL080276) dJ101K10.2 (regulator of G-protein signaling 17 (RGS17)
(RGSZ2)) [Homo sapiens]
Length = 218
Score = 116 bits (289), Expect = 8e-26
Identities = 50/126 (39%), Positives = 86/126 (67%)
Query: 13 DEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQ 72
+E L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ + EKA+
Sbjct: 84 EEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIEEKARM 143
Query: 73 IYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEF 132
IYE++I +PKEV++D +++ +NL++P+ ++ AQ +I+ LM +DS PRF+ S+
Sbjct: 144 IYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRFLNSQI 203
Query: 133 YQELIK 138
Y+ ++
Sbjct: 204 YKSFVE 209
>gb|AAF33236.1|AF220159_1 (AF220159) RGS-1 [Caenorhabditis elegans]
Length = 201
Score = 115 bits (284), Expect = 3e-25
Identities = 55/127 (43%), Positives = 82/127 (64%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
S + W+ S D L+ G F FLKSE+S+EN+ FW ACE+ K+ K+ KM EKA
Sbjct: 31 SYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSEYSDENILFWQACEELKREKNSEKMEEKA 90
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE+FI +PKEV++D ++I N+ P+ ++F+ AQ +I+ LM +DS PRF+ S
Sbjct: 91 RIIYEDFISILSPKEVSLDSKVREIVNTNMSRPTQNTFEDAQHQIYQLMARDSYPRFLTS 150
Query: 131 EFYQELI 137
FY+E +
Sbjct: 151 IFYRETL 157
>sp|P34295|YKO7_CAEEL HYPOTHETICAL 29.5 KD PROTEIN C05B5.7 IN CHROMOSOME III
emb|CAA83595.1| (Z32679) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=197.2,
E-value=8.5e-56, N=1 [Caenorhabditis elegans]
Length = 254
Score = 115 bits (284), Expect = 3e-25
Identities = 55/127 (43%), Positives = 82/127 (64%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
S + W+ S D L+ G F FLKSE+S+EN+ FW ACE+ K+ K+ KM EKA
Sbjct: 31 SYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSEYSDENILFWQACEELKREKNSEKMEEKA 90
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE+FI +PKEV++D ++I N+ P+ ++F+ AQ +I+ LM +DS PRF+ S
Sbjct: 91 RIIYEDFISILSPKEVSLDSKVREIVNTNMSRPTQNTFEDAQHQIYQLMARDSYPRFLTS 150
Query: 131 EFYQELI 137
FY+E +
Sbjct: 151 IFYRETL 157
>pir||S43576 C05B5.7 protein (clone C05B5) - Caenorhabditis elegans
Length = 251
Score = 115 bits (284), Expect = 3e-25
Identities = 55/127 (43%), Positives = 82/127 (64%)
Query: 11 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 70
S + W+ S D L+ G F FLKSE+S+EN+ FW ACE+ K+ K+ KM EKA
Sbjct: 28 SYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSEYSDENILFWQACEELKREKNSEKMEEKA 87
Query: 71 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 130
+ IYE+FI +PKEV++D ++I N+ P+ ++F+ AQ +I+ LM +DS PRF+ S
Sbjct: 88 RIIYEDFISILSPKEVSLDSKVREIVNTNMSRPTQNTFEDAQHQIYQLMARDSYPRFLTS 147
Query: 131 EFYQELI 137
FY+E +
Sbjct: 148 IFYRETL 154
>pir||T21035 hypothetical protein F16H9.1b - Caenorhabditis elegans
emb|CAB54219.1| (Z50005) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1 [Caenorhabditis elegans]
emb|CAB54230.1| (Z67882) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1 [Caenorhabditis elegans]
Length = 181
Score = 113 bits (281), Expect = 7e-25
Identities = 52/120 (43%), Positives = 80/120 (66%)
Query: 18 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 77
W S + L+++ G F FLK E+S+EN+ FW ACE+ K+ K+ K+ EKA+ IYE+F
Sbjct: 52 WSQSFENLMKHRAGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDF 111
Query: 78 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 137
I +PKEV++D ++I N+ PS S+FD AQ +I+ LM++DS PRF+ S Y+ ++
Sbjct: 112 ISILSPKEVSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKTVM 171
>sp|P49808|YUE1_CAEEL HYPOTHETICAL 19.6 KDA PROTEIN F16H9.1 IN CHROMOSOME X
pir||T21034 hypothetical protein F16H9.1a - Caenorhabditis elegans
emb|CAA90295.1| (Z50005) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1~cDNA EST yk78b5.5 comes from this
gene~cDNA EST yk78b5.3 comes from this gene~cDNA EST
yk512h4.5 comes from this gene [Cae>
emb|CAA91803.1| (Z67882) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1~cDNA EST yk78b5.5 comes from this
gene~cDNA EST yk78b5.3 comes from this gene~cDNA EST
yk512h4.5 comes from this gene [Cae>
gb|AAF33782.1|AF220265_1 (AF220265) RGS-2 [Caenorhabditis elegans]
Length = 169
Score = 113 bits (281), Expect = 7e-25
Identities = 52/120 (43%), Positives = 80/120 (66%)
Query: 18 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 77
W S + L+++ G F FLK E+S+EN+ FW ACE+ K+ K+ K+ EKA+ IYE+F
Sbjct: 40 WSQSFENLMKHRAGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDF 99
Query: 78 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 137
I +PKEV++D ++I N+ PS S+FD AQ +I+ LM++DS PRF+ S Y+ ++
Sbjct: 100 ISILSPKEVSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKTVM 159
Database: nr
Number of letters in database: 189,012,571
Number of sequences in database: 598,029
Lambda K H
0.317 0.132 0.370
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47487803
Number of Sequences: 598029
Number of extensions: 1686670
Number of successful extensions: 5545
Number of sequences better than 10.0: 187
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 5281
Number of HSP's gapped (non-prelim): 194
length of query: 138
length of database: 189,012,571
effective HSP length: 57
effective length of query: 81
effective length of database: 154,924,918
effective search space: 12548918358
effective search space used: 12548918358
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 67 (30.5 bits)
