Score E
Sequences producing significant alignments: (bits) Value
ref|NP_003608.1| regulator of G-protein signalling 5; Regul... 367 e-101
ref|NP_062214.1| regulator of G-protein signaling 5 [Rattus... 330 5e-90
ref|NP_033089.1| regulator of G-protein signaling 5 [Mus mu... 328 2e-89
ref|XP_002185.1| regulator of G-protein signalling 5 [Homo ... 315 2e-85
pir||JC7228 G-protein signaling regulator 5 homolog - clawe... 299 1e-80
ref|NP_005604.1| regulator of G-protein signaling 4; RGP4 [... 197 8e-50
ref|NP_058910.1| regulator of G-protein signaling 4 [Rattus... 197 8e-50
ref|NP_033088.1| regulator of G-protein signaling 4 [Mus mu... 194 4e-49
gb|AAC16913.1| (U70427) mA28-RGS14p [Mus musculus] 186 2e-46
ref|NP_002919.1| regulator of G-protein signalling 16; Regu... 182 2e-45
gb|AAG18443.1|AF300649_1 (AF300649) regulator of G-protein ... 182 2e-45
sp|O46471|RGSG_BOVIN REGULATOR OF G-PROTEIN SIGNALING 16 (R... 182 3e-45
ref|XP_002066.1| regulator of G-protein signalling 16 [Homo... 181 4e-45
sp|O15492|RGSG_HUMAN REGULATOR OF G-PROTEIN SIGNALING 16 (R... 181 4e-45
ref|NP_062217.1| regulator of G-protein signaling 8 [Rattus... 181 5e-45
sp|P97428|RGSG_MOUSE REGULATOR OF G-PROTEIN SIGNALING 16 (R... 180 1e-44
gb|AAF70201.1|AF263451_1 (AF263451) RGS4 protein [Xenopus l... 179 2e-44
sp|P56700|RGSG_RAT REGULATOR OF G-PROTEIN SIGNALING 16 (RGS... 178 3e-44
ref|XP_005324.1| regulator of G-protein signalling 3 [Homo ... 175 4e-43
ref|NP_066929.1| regulator of G-protein signalling 3 [Homo ... 175 4e-43
gb|AAF34626.1|AF215669_1 (AF215669) regulator of G-protein ... 171 3e-42
gb|AAF34627.1|AF215670_1 (AF215670) regulator of G-protein ... 170 8e-42
gb|AAF85981.1|AF279918_1 (AF279918) regulator of G-protein ... 167 7e-41
gb|AAF80227.1|AF076642_1 (AF076642) regulator of G-protein ... 167 7e-41
gb|AAF34625.1|AF215668_1 (AF215668) regulator of G-protein ... 165 3e-40
ref|NP_002914.1| regulator of G-protein signalling 2, 24kD;... 165 3e-40
ref|NP_033087.1| regulator of G-protein signaling 2 [Mus mu... 163 1e-39
ref|NP_056626.1| regulator of G-protein signaling 1 [Mus mu... 140 1e-32
ref|XP_001330.1| regulator of G-protein signalling 1 [Homo ... 138 3e-32
ref|NP_002913.1| regulator of G-protein signalling 1; Regul... 138 5e-32
sp|O14921|RGSD_HUMAN REGULATOR OF G-PROTEIN SIGNALING 13 (R... 130 9e-30
gb|AAF57785.1| (AE003802) EG:52C10.2 gene product [Drosophi... 126 1e-28
sp|P49800|RGS5_RAT REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5... 124 5e-28
gb|AAD53050.1| (AF139872) regulator of G-protein signalling... 123 2e-27
gb|AAD45947.1|AF151967_1 (AF151967) RGS protein Gz-GAP [Gal... 122 2e-27
gb|AAD45948.1|AF151968_1 (AF151968) RGS protein RGS-17 [Gal... 122 3e-27
ref|NP_003693.1| regulator of Gz-selective protein signalin... 121 6e-27
sp|P79348|RGSX_BOVIN RETINA SPECIFIC REGULATOR OF G-PROTEIN... 121 6e-27
ref|NP_064342.1| regulator of G-protein signaling 17; regul... 120 1e-26
pir||T13580 hypothetical protein 52C10.2 - fruit fly (Droso... 120 1e-26
gb|AAF33236.1|AF220159_1 (AF220159) RGS-1 [Caenorhabditis e... 118 3e-26
sp|P34295|YKO7_CAEEL HYPOTHETICAL 29.5 KD PROTEIN C05B5.7 I... 118 3e-26
pir||S43576 C05B5.7 protein (clone C05B5) - Caenorhabditis ... 118 3e-26
ref|XP_004378.1| regulator of G-protein signalling 17 [Homo... 118 4e-26
ref|NP_036551.2| regulator of G-protein signalling 17 [Homo... 118 4e-26
emb|CAB65995.1| (AL080276) dJ101K10.2 (regulator of G-prote... 118 4e-26
gb|AAF05757.1|AF191554_1 (AF191554) regulator of G-protein ... 117 7e-26
ref|NP_067349.1| regulator of G-protein signaling Z1 [Mus m... 117 7e-26
pir||T21035 hypothetical protein F16H9.1b - Caenorhabditis ... 113 1e-24
sp|P49808|YUE1_CAEEL HYPOTHETICAL 19.6 KDA PROTEIN F16H9.1 ... 113 1e-24
>ref|NP_003608.1| regulator of G-protein signalling 5; Regulator of G protein
signaling-5 [Homo sapiens]
sp|O15539|RGS5_HUMAN REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5)
dbj|BAA22889.1| (AB008109) RGS5 [Homo sapiens]
gb|AAB84001.1| (AF030108) RGS5 [Homo sapiens]
gb|AAD40957.1|AF159570_1 (AF159570) regulator of G-protein signalling 5 [Homo sapiens]
Length = 181
Score = 367 bits (931), Expect = e-101
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ
Sbjct: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF
Sbjct: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI
Sbjct: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
Query: 181 K 181
K
Sbjct: 181 K 181
>ref|NP_062214.1| regulator of G-protein signaling 5 [Rattus norvegicus]
gb|AAF73424.1|AF241259_1 (AF241259) RGS5 [Rattus norvegicus]
Length = 181
Score = 330 bits (838), Expect = 5e-90
Identities = 162/180 (90%), Positives = 169/180 (93%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
MCKGLAALPHSCLERAKEIKIKLGILLQKPDS DLVIPYNEKPEKPAK K SL+E LQ
Sbjct: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPAKAHKPSLEEVLQ 60
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
WR SLDKLLQ+NYG ASFKSFLKSEFSEENLEFW+ACE+YKKIKSP KMAEKAKQIYEEF
Sbjct: 61 WRQSLDKLLQSNYGFASFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAEKAKQIYEEF 120
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
IQTEAPKEVNIDHFTKDITMKNLVEPS SFD+AQKRI+ALMEKDSLPRFVRSEFY+ELI
Sbjct: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSPHSFDLAQKRIYALMEKDSLPRFVRSEFYKELI 180
>ref|NP_033089.1| regulator of G-protein signaling 5 [Mus musculus]
sp|O08850|RGS5_MOUSE REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5)
gb|AAB50618.1| (U67188) G protein signaling regulator RGS5 [Mus musculus]
Length = 181
Score = 328 bits (833), Expect = 2e-89
Identities = 161/181 (88%), Positives = 169/181 (92%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
MCKGLAALPHSCLERAKEIKIKLGILLQKPDS DLVIPYNEKPEKPA K SL+E LQ
Sbjct: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSAVDLVIPYNEKPEKPANGHKPSLEEVLQ 60
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
WR SLDKLLQN+YG A+FKSFLKSEFSEENLEFW+ACE+YKKIKSP KMAEKAKQIYEEF
Sbjct: 61 WRQSLDKLLQNSYGFATFKSFLKSEFSEENLEFWVACENYKKIKSPIKMAEKAKQIYEEF 120
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
IQTEAPKEVNIDHFTKDITMKNLVEPS SFD+AQKRI+ALMEKDSLPRFVRSEFY+ELI
Sbjct: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSPRSFDLAQKRIYALMEKDSLPRFVRSEFYKELI 180
Query: 181 K 181
K
Sbjct: 181 K 181
>ref|XP_002185.1| regulator of G-protein signalling 5 [Homo sapiens]
Length = 157
Score = 315 bits (798), Expect = 2e-85
Identities = 155/155 (100%), Positives = 155/155 (100%)
Query: 27 LQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEF 86
LQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEF
Sbjct: 3 LQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEF 62
Query: 87 SEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEP 146
SEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEP
Sbjct: 63 SEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEP 122
Query: 147 SLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 181
SLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK
Sbjct: 123 SLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 157
>pir||JC7228 G-protein signaling regulator 5 homolog - clawed frog
Length = 181
Score = 299 bits (758), Expect = 1e-80
Identities = 143/181 (79%), Positives = 163/181 (90%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
MCKGLAALPH+CLERAKEIK KLG LLQKP+S DL+IPY +KPEKP K K S +EA Q
Sbjct: 1 MCKGLAALPHTCLERAKEIKTKLGTLLQKPESAIDLIIPYPDKPEKPPKASKPSAEEAGQ 60
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
WRDSL+KLL+N+YGL+ F+SFLKSEFSEEN+EFW+ACEDYKK KSP+KM KAK+IYEEF
Sbjct: 61 WRDSLEKLLENSYGLSVFQSFLKSEFSEENIEFWMACEDYKKAKSPSKMTTKAKKIYEEF 120
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
IQTEAP+EVNIDHFTK +TMKNLVEPS +SF++AQK+I ALMEKDSLPRFVRSEFYQELI
Sbjct: 121 IQTEAPREVNIDHFTKAVTMKNLVEPSSASFELAQKKIFALMEKDSLPRFVRSEFYQELI 180
Query: 181 K 181
K
Sbjct: 181 K 181
>ref|NP_005604.1| regulator of G-protein signaling 4; RGP4 [Homo sapiens]
sp|P49798|RGS4_HUMAN REGULATOR OF G-PROTEIN SIGNALING 4 (RGS4) (RGP4)
pir||S78221 G-protein signaling regulator RGP4 - human
gb|AAC50395.1| (U27768) RGP4 [Homo sapiens]
prf||2206475C G protein signaling regulator [Homo sapiens]
Length = 205
Score = 197 bits (495), Expect = 8e-50
Identities = 95/180 (52%), Positives = 133/180 (73%), Gaps = 2/180 (1%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
MCKGLA LP SCL AK++K +LG LLQK DS + K +K Q+ S +E +
Sbjct: 1 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHN--SSHNKKDKVVICQRVSQEEVKK 58
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
W +SL+ L+ + GLA+FK+FLKSE+SEEN++FWI+CE+YKKIKSP+K++ KAK+IY EF
Sbjct: 59 WAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF 118
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
I +A KEVN+D T++ T +N++EP+++ FD AQK+I LMEKDS RF++S FY +L+
Sbjct: 119 ISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLV 178
>ref|NP_058910.1| regulator of G-protein signaling 4 [Rattus norvegicus]
sp|P49799|RGS4_RAT REGULATOR OF G-PROTEIN SIGNALING 4 (RGS4) (RGP4)
pdb|1AGR|E Chain E, Complex Of Alf4-Activated Gi-Alpha-1 With Rgs4
pdb|1AGR|H Chain H, Complex Of Alf4-Activated Gi-Alpha-1 With Rgs4
gb|AAC52440.1| (U27767) RGP4 [Rattus norvegicus]
gb|AAD12065.1| (AF117211) regulator of G-protein signaling 4 [Rattus norvegicus]
prf||2206475B G protein signaling regulator [Rattus norvegicus]
Length = 205
Score = 197 bits (495), Expect = 8e-50
Identities = 95/179 (53%), Positives = 132/179 (73%), Gaps = 2/179 (1%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
MCKGLA LP SCL AK++K +LG LLQK DS + K +K Q+ S +E +
Sbjct: 1 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHS--SSHSKKDKVVTCQRVSQEEVKK 58
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
W +SL+ L+ + GLA+FK+FLKSE+SEEN++FWI+CE+YKKIKSP+K++ KAK+IY EF
Sbjct: 59 WAESLENLINHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF 118
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
I +A KEVN+D T++ T +N++EP+++ FD AQK+I LMEKDS RF++S FY +L
Sbjct: 119 ISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDL 177
>ref|NP_033088.1| regulator of G-protein signaling 4 [Mus musculus]
sp|O08899|RGS4_MOUSE REGULATOR OF G-PROTEIN SIGNALING 4 (RGS4)
dbj|BAA20400.1| (AB004315) RGS4 [Mus musculus]
Length = 205
Score = 194 bits (489), Expect = 4e-49
Identities = 93/179 (51%), Positives = 132/179 (72%), Gaps = 2/179 (1%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQ 60
MCKGLA LP SCL AK++K +LG LLQK DS + K +K Q+ S +E +
Sbjct: 1 MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHS--SSHSKKDKVVTCQRVSQEEVKK 58
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
W +SL+ L+ + GLA+FK+FLKSE+SEEN++FWI+CE+YKKIKSP+K++ KAK+IY EF
Sbjct: 59 WAESLENLIHHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEF 118
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
I +A KEVN+D T++ T +N+++P+++ FD AQK+I LME+DS RF++S FY +L
Sbjct: 119 ISVQATKEVNLDSCTREETSRNMLQPTITCFDEAQKKIFNLMERDSYRRFLKSRFYLDL 177
>gb|AAC16913.1| (U70427) mA28-RGS14p [Mus musculus]
Length = 202
Score = 186 bits (467), Expect = 2e-46
Identities = 92/180 (51%), Positives = 127/180 (70%), Gaps = 1/180 (0%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLV-IPYNEKPEKPAKTQKTSLDEAL 59
MC+ LA P++CLERAKE K +LGI L K + D I E K K ++ ++ L
Sbjct: 1 MCRTLATFPNTCLERAKEFKTRLGIFLHKSELSSDTGGISKFEWASKHNKENRSFSEDVL 60
Query: 60 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE 119
WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A +A QI+EE
Sbjct: 61 GWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE 120
Query: 120 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
+I++EAPKEVNIDH T+++T NL + S FD+AQ + LMEKDS PRF++S Y++L
Sbjct: 121 YIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDL 180
>ref|NP_002919.1| regulator of G-protein signalling 16; Regulator of G protein
signaling-16 [Homo sapiens]
gb|AAC16912.1| (U70426) A28-RGS14p [Homo sapiens]
Length = 202
Score = 182 bits (458), Expect = 2e-45
Identities = 92/180 (51%), Positives = 125/180 (69%), Gaps = 1/180 (0%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDL-VIPYNEKPEKPAKTQKTSLDEAL 59
MC+ LAA P +CLERAKE K +LGI L K + D +E K +K + ++ L
Sbjct: 1 MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKSEWGSKHSKENRNFSEDVL 60
Query: 60 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE 119
WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A +A QI+EE
Sbjct: 61 GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE 120
Query: 120 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
FI +EAPKEVNIDH T+++T NL + + FD AQ + LMEKDS PRF++S Y++L
Sbjct: 121 FICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL 180
>gb|AAG18443.1|AF300649_1 (AF300649) regulator of G-protein signaling [Homo sapiens]
Length = 180
Score = 182 bits (457), Expect = 2e-45
Identities = 86/166 (51%), Positives = 120/166 (71%), Gaps = 2/166 (1%)
Query: 15 RAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYG 74
R K ++ +LG L K DS D +KP + K + S +EA +W DS D LL + YG
Sbjct: 9 RNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATRWADSFDVLLSHKYG 66
Query: 75 LASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHF 134
+A+F++FLK+EFSEENLEFW+ACE++KK +S AK+ KA +I+EEF+ +AP+EVNID
Sbjct: 67 VAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVSKAHRIFEEFVDVQAPREVNIDFQ 126
Query: 135 TKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
T++ T KNL EPSL+ FD AQ ++H+LMEKDS PRF+RS+ Y +L+
Sbjct: 127 TREATRKNLQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL 172
>sp|O46471|RGSG_BOVIN REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R)
gb|AAC99484.1| (AF011361) regulator of G-protein signaling 16/-r [Bos taurus]
Length = 202
Score = 182 bits (456), Expect = 3e-45
Identities = 91/180 (50%), Positives = 125/180 (68%), Gaps = 1/180 (0%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDL-VIPYNEKPEKPAKTQKTSLDEAL 59
MC+ LAA P SCLERAKE K +LGI L K + D + E K +K K ++ L
Sbjct: 1 MCRTLAAFPTSCLERAKEFKTRLGIFLHKSELGSDTGSVGKFEWGSKHSKEGKNFSEDVL 60
Query: 60 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE 119
W++S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KK++S K+ +A +I+EE
Sbjct: 61 GWKESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKLRSATKLGSRAHRIFEE 120
Query: 120 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
FI +EAPKEVNIDH T+++T NL + FD AQ ++ ALMEKDS PRF++S Y++L
Sbjct: 121 FICSEAPKEVNIDHETRELTRTNLQAATAVCFDAAQWKVRALMEKDSYPRFLKSPAYRDL 180
>ref|XP_002066.1| regulator of G-protein signalling 16 [Homo sapiens]
Length = 232
Score = 181 bits (455), Expect = 4e-45
Identities = 92/180 (51%), Positives = 124/180 (68%), Gaps = 1/180 (0%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYN-EKPEKPAKTQKTSLDEAL 59
MC+ LAA P +CLERAKE K +LGI L K + D E K +K + ++ L
Sbjct: 31 MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL 90
Query: 60 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE 119
WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A +A QI+EE
Sbjct: 91 GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE 150
Query: 120 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
FI +EAPKEVNIDH T+++T NL + + FD AQ + LMEKDS PRF++S Y++L
Sbjct: 151 FICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL 210
>sp|O15492|RGSG_HUMAN REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R) (A28-RGS14P)
gb|AAC52040.1| (U94829) retinally abundant regulator of G-protein signaling hRGS-r
[Homo sapiens]
gb|AAC39642.1| (AF009356) regulator of G-protein signaling-16 [Homo sapiens]
Length = 202
Score = 181 bits (455), Expect = 4e-45
Identities = 92/180 (51%), Positives = 124/180 (68%), Gaps = 1/180 (0%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYN-EKPEKPAKTQKTSLDEAL 59
MC+ LAA P +CLERAKE K +LGI L K + D E K +K + ++ L
Sbjct: 1 MCRTLAAFPTTCLERAKEFKTRLGIFLHKSELGCDTGSTGKFEWGSKHSKENRNFSEDVL 60
Query: 60 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE 119
WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A +A QI+EE
Sbjct: 61 GWRESFDLLLSSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHQIFEE 120
Query: 120 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
FI +EAPKEVNIDH T+++T NL + + FD AQ + LMEKDS PRF++S Y++L
Sbjct: 121 FICSEAPKEVNIDHETRELTRMNLQTATATCFDAAQGKTRTLMEKDSYPRFLKSPAYRDL 180
>ref|NP_062217.1| regulator of G-protein signaling 8 [Rattus norvegicus]
sp|P49804|RGS8_RAT REGULATOR OF G-PROTEIN SIGNALING 8 (RGS8)
dbj|BAA23680.1| (AB006013) RGS8 [Rattus norvegicus]
Length = 180
Score = 181 bits (454), Expect = 5e-45
Identities = 85/166 (51%), Positives = 120/166 (72%), Gaps = 2/166 (1%)
Query: 15 RAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYG 74
R K ++ +LG L K DS D +KP + K + S +EA +W DS D LL + YG
Sbjct: 9 RNKGMRTRLGCLSHKSDSCSDFTAILPDKPNRALK--RLSTEEATRWADSFDVLLSHKYG 66
Query: 75 LASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHF 134
+A+F++FLK+EFSEENLEFW+ACE++KK +S AK+ KA +I+EEF+ +AP+EVNID
Sbjct: 67 VAAFRAFLKTEFSEENLEFWLACEEFKKTRSTAKLVTKAHRIFEEFVDVQAPREVNIDFQ 126
Query: 135 TKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
T++ T KN+ EPSL+ FD AQ ++H+LMEKDS PRF+RS+ Y +L+
Sbjct: 127 TREATRKNMQEPSLTCFDQAQGKVHSLMEKDSYPRFLRSKMYLDLL 172
>sp|P97428|RGSG_MOUSE REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R) (A28-RGS14P)
gb|AAC52927.1| (U72881) RGS-r protein [Mus musculus]
gb|AAB50619.1| (U67189) G protein signaling regulator RGS16 [Mus musculus]
gb|AAC53549.1| (U94828) retinally abundant regulator of G-protein signaling mRGS-r
[Mus musculus]
Length = 201
Score = 180 bits (451), Expect = 1e-44
Identities = 91/180 (50%), Positives = 126/180 (69%), Gaps = 2/180 (1%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLV-IPYNEKPEKPAKTQKTSLDEAL 59
MC+ LA P++CLERAKE K +LGI L K + D I E K K + S ++ L
Sbjct: 1 MCRTLATFPNTCLERAKEFKTRLGIFLHKSELSSDTGGISKFEWASKHNKERSFS-EDVL 59
Query: 60 QWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEE 119
WR+S D LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A +A I++E
Sbjct: 60 GWRESFDLLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFDE 119
Query: 120 FIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQEL 179
+I++EAPKEVNIDH T+++T NL + S FD+AQ + LMEKDS PRF++S Y++L
Sbjct: 120 YIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRDL 179
>gb|AAF70201.1|AF263451_1 (AF263451) RGS4 protein [Xenopus laevis]
Length = 204
Score = 179 bits (449), Expect = 2e-44
Identities = 88/183 (48%), Positives = 132/183 (72%), Gaps = 9/183 (4%)
Query: 1 MCKGLAAL---PHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDE 57
MCKGLA + P +CL+ AK+IK +LG LLQK D ++ +KP +Q+ +E
Sbjct: 1 MCKGLAGVTTFPATCLKSAKDIKHRLGFLLQKADGC-----EHSPGVKKPG-SQRVRQEE 54
Query: 58 ALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIY 117
+W +SL+ L+ N GLA+F+SFL+SE+SEEN++FW ACE+YKKIK+ A++ E+A++IY
Sbjct: 55 VKKWAESLENLINNECGLAAFRSFLQSEYSEENIDFWTACENYKKIKTQARLPEQAQKIY 114
Query: 118 EEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQ 177
E+FI EA KEVN+D T++ T N+++P+ S+FD AQ +I LMEKDS RF++S+FY
Sbjct: 115 EDFISVEATKEVNLDSVTREETSNNILQPTYSTFDEAQHKIFILMEKDSYRRFLKSKFYL 174
Query: 178 ELI 180
+++
Sbjct: 175 DIV 177
>sp|P56700|RGSG_RAT REGULATOR OF G-PROTEIN SIGNALING 16 (RGS16) (RETINALLY ABUNDANT
REGULATOR OF G-PROTEIN SIGNALING) (RGS-R)
Length = 199
Score = 178 bits (447), Expect = 3e-44
Identities = 89/181 (49%), Positives = 126/181 (69%), Gaps = 4/181 (2%)
Query: 1 MCKGLAALPHSCLERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQK--TSLDEA 58
MC+ +A P++CLERAKE K +LGI L K + D N K E +K K + ++
Sbjct: 1 MCRTIATFPNTCLERAKEFKTRLGIFLHKSELSSDT--GGNGKFEWASKLSKERSFSEDV 58
Query: 59 LQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYE 118
L WR+S LL + G+A+F +FLK+EFSEENLEFW+ACE++KKI+S K+A +A I++
Sbjct: 59 LGWRESFQSLLNSKNGVAAFHAFLKTEFSEENLEFWLACEEFKKIRSATKLASRAHHIFD 118
Query: 119 EFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQE 178
E+I++EAPKEVNIDH T+++T NL + S FD+AQ + LMEKDS PRF++S Y++
Sbjct: 119 EYIRSEAPKEVNIDHETRELTKTNLQAATTSCFDVAQGKTRTLMEKDSYPRFLKSPAYRD 178
Query: 179 L 179
L
Sbjct: 179 L 179
>ref|XP_005324.1| regulator of G-protein signalling 3 [Homo sapiens]
Length = 460
Score = 175 bits (438), Expect = 4e-43
Identities = 88/165 (53%), Positives = 122/165 (73%), Gaps = 3/165 (1%)
Query: 16 AKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGL 75
AK++K KLGI ++ +S G P K +K K+ K + +EAL+W +SL+KLL + YGL
Sbjct: 290 AKDMKNKLGIFRRRNESPG---APPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGL 346
Query: 76 ASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFT 135
A F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+I+ E+I +A KEVN+D +T
Sbjct: 347 AVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYT 406
Query: 136 KDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
++ T NL + FD+AQKRI LMEKDS PRF+RS+ Y +LI
Sbjct: 407 REHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLI 451
>ref|NP_066929.1| regulator of G-protein signalling 3 [Homo sapiens]
sp|P49796|RGS3_HUMAN REGULATOR OF G-PROTEIN SIGNALING 3 (RGS3) (RGP3)
pir||S78089 G-protein signaling regulator RGS3 - human
gb|AAC50394.1| (U27655) RGP3 [Homo sapiens]
prf||2206475A G protein signaling regulator [Homo sapiens]
Length = 519
Score = 175 bits (438), Expect = 4e-43
Identities = 88/165 (53%), Positives = 122/165 (73%), Gaps = 3/165 (1%)
Query: 16 AKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGL 75
AK++K KLGI ++ +S G P K +K K+ K + +EAL+W +SL+KLL + YGL
Sbjct: 349 AKDMKNKLGIFRRRNESPG---APPAGKADKMMKSFKPTSEEALKWGESLEKLLVHKYGL 405
Query: 76 ASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFT 135
A F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+I+ E+I +A KEVN+D +T
Sbjct: 406 AVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMASKAKKIFAEYIAIQACKEVNLDSYT 465
Query: 136 KDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
++ T NL + FD+AQKRI LMEKDS PRF+RS+ Y +LI
Sbjct: 466 REHTKDNLQSVTRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLI 510
>gb|AAF34626.1|AF215669_1 (AF215669) regulator of G-protein signaling 3s [Mus musculus]
Length = 192
Score = 171 bits (430), Expect = 3e-42
Identities = 86/168 (51%), Positives = 122/168 (72%), Gaps = 3/168 (1%)
Query: 13 LERAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNN 72
++ AK++K KL I ++ +S G K +K K+ K + +EAL+W +SL+KLL +
Sbjct: 19 MKEAKDMKNKLAIFRRRNESPGAQPA---SKTDKTTKSFKPTSEEALKWSESLEKLLLHK 75
Query: 73 YGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNID 132
YGL F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+I+ EFI +A KEVN+D
Sbjct: 76 YGLEVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKKIFAEFIAIQACKEVNLD 135
Query: 133 HFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
+T++ T +NL + FD+AQKRI LMEKDS PRF+RS+ Y +LI
Sbjct: 136 SYTREHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLI 183
>gb|AAF34627.1|AF215670_1 (AF215670) regulator of G-protein signaling 3 [Mus musculus]
Length = 297
Score = 170 bits (427), Expect = 8e-42
Identities = 86/165 (52%), Positives = 120/165 (72%), Gaps = 3/165 (1%)
Query: 16 AKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGL 75
AK++K KL I ++ +S G K +K K+ K + +EAL+W +SL+KLL + YGL
Sbjct: 127 AKDMKNKLAIFRRRNESPGAQPA---SKTDKTTKSFKPTSEEALKWSESLEKLLLHKYGL 183
Query: 76 ASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFT 135
F++FL++EFSEENLEFW+ACED+KK+KS +KMA KAK+I+ EFI +A KEVN+D +T
Sbjct: 184 EVFQAFLRTEFSEENLEFWLACEDFKKVKSQSKMAAKAKKIFAEFIAIQACKEVNLDSYT 243
Query: 136 KDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
++ T +NL + FD+AQKRI LMEKDS PRF+RS+ Y +LI
Sbjct: 244 REHTKENLQSITRGCFDLAQKRIFGLMEKDSYPRFLRSDLYLDLI 288
>gb|AAF85981.1|AF279918_1 (AF279918) regulator of G-protein signaling protein 2 [Rattus
norvegicus]
Length = 211
Score = 167 bits (419), Expect = 7e-41
Identities = 82/165 (49%), Positives = 113/165 (67%), Gaps = 3/165 (1%)
Query: 17 KEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLA 76
K+ K +L LQ + G P K K K S +EAL W ++ D+LL + YGLA
Sbjct: 39 KDWKTRLSYFLQNSSTPGK---PKTGKKSKQQTFIKPSPEEALLWAEAFDELLASKYGLA 95
Query: 77 SFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTK 136
+F++FLKSEF EEN+EFW+ACED+KK KSP K++ KA++IY +FI+ EAPKE+NID TK
Sbjct: 96 AFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTK 155
Query: 137 DITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 181
+ +N+ E + F AQKR+++LME +S PRF+ SEFYQ+L K
Sbjct: 156 TLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK 200
>gb|AAF80227.1|AF076642_1 (AF076642) regulator of G-protein signaling 13 [Homo sapiens]
Length = 235
Score = 167 bits (419), Expect = 7e-41
Identities = 82/167 (49%), Positives = 119/167 (71%), Gaps = 3/167 (1%)
Query: 15 RAKEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYG 74
RAKE + +L +L+QKP+ D + + AK + S +EA++W +S DKLL + G
Sbjct: 40 RAKEKRNRLSLLVQKPEFHEDT---RSSRSGHLAKETRVSPEEAVKWGESFDKLLSHRDG 96
Query: 75 LASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHF 134
L +F FLK+EFSEEN+EFWIACED+KK K P ++ KAK IYE+FIQT+APKEVN+D
Sbjct: 97 LEAFTRFLKTEFSEENIEFWIACEDFKKSKGPQQIHLKAKAIYEKFIQTDAPKEVNLDFH 156
Query: 135 TKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 181
TK++ ++ +P+L SFD AQ R++ LME+DS RF++S+ Y +L++
Sbjct: 157 TKEVITNSITQPTLHSFDAAQSRVYQLMEQDSYTRFLKSDIYLDLME 203
>gb|AAF34625.1|AF215668_1 (AF215668) regulator of G-protein signaling 2 [Mus musculus]
Length = 211
Score = 165 bits (414), Expect = 3e-40
Identities = 81/165 (49%), Positives = 112/165 (67%), Gaps = 3/165 (1%)
Query: 17 KEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLA 76
K+ K +L LQ + G P K K K S +EA W ++ D+LL + YGLA
Sbjct: 39 KDWKTRLSYFLQNSSAPGK---PKTGKKSKQQTFIKPSPEEAQLWAEAFDELLASKYGLA 95
Query: 77 SFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTK 136
+F++FLKSEF EEN+EFW+ACED+KK KSP K++ KA++IY +FI+ EAPKE+NID TK
Sbjct: 96 AFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTK 155
Query: 137 DITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 181
+ +N+ E + F AQKR+++LME +S PRF+ SEFYQ+L K
Sbjct: 156 SLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK 200
>ref|NP_002914.1| regulator of G-protein signalling 2, 24kD; G0 to G1 switch
regulatory 8, 24kD [Homo sapiens]
ref|XP_001898.1| regulator of G-protein signalling 2, 24kD [Homo sapiens]
sp|P41220|RGS2_HUMAN REGULATOR OF G-PROTEIN SIGNALING 2 (RGS2) (G0/G1 SWITCH REGULATORY
PROTEIN 8)
pir||I53020 G-0/G-1 switch regulatory protein 8 - human
gb|AAA20680.1| (L13391) helix-loop-helix phosphoprotein [Homo sapiens]
gb|AAC37587.1| (L13463) helix-loop-helix phosphoprotein [Homo sapiens]
emb|CAB62512.1| (AL035407) dJ419C19.2 (regulator of G-protein signalling 2, 24kD)
[Homo sapiens]
Length = 211
Score = 165 bits (413), Expect = 3e-40
Identities = 81/165 (49%), Positives = 112/165 (67%), Gaps = 3/165 (1%)
Query: 17 KEIKIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLA 76
K+ K +L LQ + G P K K K S +EA W ++ D+LL + YGLA
Sbjct: 39 KDWKTRLSYFLQNSSTPGK---PKTGKKSKQQAFIKPSPEEAQLWSEAFDELLASKYGLA 95
Query: 77 SFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTK 136
+F++FLKSEF EEN+EFW+ACED+KK KSP K++ KA++IY +FI+ EAPKE+NID TK
Sbjct: 96 AFRAFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTK 155
Query: 137 DITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 181
+ +N+ E + F AQKR+++LME +S PRF+ SEFYQ+L K
Sbjct: 156 TLIAQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK 200
>ref|NP_033087.1| regulator of G-protein signaling 2 [Mus musculus]
sp|O08849|RGS2_MOUSE REGULATOR OF G-PROTEIN SIGNALING 2 (RGS2)
gb|AAB50617.1| (U67187) G protein signaling regulator RGS2 [Mus musculus]
Length = 211
Score = 163 bits (409), Expect = 1e-39
Identities = 80/162 (49%), Positives = 110/162 (67%), Gaps = 3/162 (1%)
Query: 20 KIKLGILLQKPDSVGDLVIPYNEKPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFK 79
K +L LQ + G P K K K S +EA W ++ D+LL + YGLA+F+
Sbjct: 42 KTRLSYFLQNSSAPGK---PKTGKKSKQQTFIKPSPEEAHVWAEAFDELLASKYGLAAFR 98
Query: 80 SFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDIT 139
+FLKSEF EEN+EFW+ACED+KK KSP K++ KA++IY +FI+ EAPKE+NID TK +
Sbjct: 99 AFLKSEFCEENIEFWLACEDFKKTKSPQKLSSKARKIYTDFIEKEAPKEINIDFQTKSLI 158
Query: 140 MKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELIK 181
+N+ E + F AQKR+++LME +S PRF+ SEFYQ+L K
Sbjct: 159 AQNIQEATSGCFTTAQKRVYSLMENNSYPRFLESEFYQDLCK 200
>ref|NP_056626.1| regulator of G-protein signaling 1 [Mus musculus]
gb|AAF34624.1|AF215667_1 (AF215667) regulator of G-protein signaling 1 [Mus musculus]
Length = 196
Score = 140 bits (349), Expect = 1e-32
Identities = 71/145 (48%), Positives = 100/145 (68%), Gaps = 2/145 (1%)
Query: 37 VIPYNEKPEKPAKTQKT-SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWI 95
+IP+ E K AK++ S +E +QW SL+KLL N G F FLKSEFSEEN+EFW+
Sbjct: 44 MIPHLESGMKSAKSKDILSAEEVMQWSQSLEKLLANQTGQNVFGRFLKSEFSEENIEFWL 103
Query: 96 ACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQ 155
ACEDYKK ++ + KA+ IY+ F+ ++A K++NID T++ T K + P+ +SFD AQ
Sbjct: 104 ACEDYKKTETDL-LHNKAENIYKAFVHSDAVKQINIDFHTRESTAKKIKTPTPTSFDEAQ 162
Query: 156 KRIHALMEKDSLPRFVRSEFYQELI 180
K I++LMEKDS PRF++S Y L+
Sbjct: 163 KVIYSLMEKDSYPRFLKSNIYLNLL 187
>ref|XP_001330.1| regulator of G-protein signalling 1 [Homo sapiens]
pir||I56165 B cell activation protein BL34 - human
gb|AAB26289.1| (S59049) BL34=B cell activation gene [human, Peptide, 196 aa] [Homo
sapiens]
Length = 196
Score = 138 bits (345), Expect = 3e-32
Identities = 71/145 (48%), Positives = 100/145 (68%), Gaps = 2/145 (1%)
Query: 37 VIPYNEKPEKPAKTQKT-SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWI 95
+IP+ E K +K++ S E +QW SL+KLL N G F SFLKSEFSEEN+EFW+
Sbjct: 44 MIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWL 103
Query: 96 ACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQ 155
ACEDYKK +S + KA++IY+ F+ ++A K++NID T++ T K + P+ + FD AQ
Sbjct: 104 ACEDYKKTESDL-LPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQ 162
Query: 156 KRIHALMEKDSLPRFVRSEFYQELI 180
K I+ LMEKDS PRF++S+ Y L+
Sbjct: 163 KVIYTLMEKDSYPRFLKSDIYLNLL 187
>ref|NP_002913.1| regulator of G-protein signalling 1; Regulator of G-protein
signaling 1; 1R20 [Homo sapiens]
sp|Q08116|RGS1_HUMAN REGULATOR OF G-PROTEIN SIGNALING 1 (RGS1) (EARLY RESPONSE PROTEIN
1R20) (B-CELL ACTIVATION PROTEIN BL34)
pir||S43436 B cell activation protein BL34 - human
emb|CAA51826.1| (X73427) 1r20 [Homo sapiens]
Length = 196
Score = 138 bits (343), Expect = 5e-32
Identities = 71/145 (48%), Positives = 99/145 (67%), Gaps = 2/145 (1%)
Query: 37 VIPYNEKPEKPAKTQKT-SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWI 95
+IP+ E K +K++ S E +QW SL+KLL N G F SFLKSEFSEEN+EFW+
Sbjct: 44 MIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWL 103
Query: 96 ACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQ 155
ACEDYKK +S + KA++IY+ F+ ++A K++NID T++ T K + P+ + FD AQ
Sbjct: 104 ACEDYKKTESDL-LPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQ 162
Query: 156 KRIHALMEKDSLPRFVRSEFYQELI 180
K I+ LMEKDS PRF++S Y L+
Sbjct: 163 KVIYTLMEKDSYPRFLKSHIYLNLL 187
>sp|O14921|RGSD_HUMAN REGULATOR OF G-PROTEIN SIGNALING 13 (RGS13)
gb|AAB84000.1| (AF030107) RGS13 [Homo sapiens]
Length = 159
Score = 130 bits (324), Expect = 9e-30
Identities = 57/139 (41%), Positives = 93/139 (66%)
Query: 43 KPEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKK 102
+ E +L+E LQW S + L+ YG + ++LK E S+EN++FW+ACE YKK
Sbjct: 13 RDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKK 72
Query: 103 IKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALM 162
I S +AK++Y+ +IQ ++P+E+NID T++ ++N+ EP+ + F+ AQK ++ M
Sbjct: 73 IASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHM 132
Query: 163 EKDSLPRFVRSEFYQELIK 181
E+DS PRF++SE YQ+L+K
Sbjct: 133 ERDSYPRFLKSEMYQKLLK 151
>gb|AAF57785.1| (AE003802) EG:52C10.2 gene product [Drosophila melanogaster]
Length = 271
Score = 126 bits (314), Expect = 1e-28
Identities = 57/129 (44%), Positives = 91/129 (70%)
Query: 51 QKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 110
++ +L+E W S DKL+++ G F++FL+SEFSEEN+ FW+ACED KK SP +
Sbjct: 126 EQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVE 185
Query: 111 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 170
EKA+ IYE++I +P+EV++D ++I +N++EP+ +FD AQ +I+ LM +DS PRF
Sbjct: 186 EKARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPRF 245
Query: 171 VRSEFYQEL 179
+ S+ ++ L
Sbjct: 246 LNSQKFKTL 254
>sp|P49800|RGS5_RAT REGULATOR OF G-PROTEIN SIGNALING 5 (RGS5)
gb|AAC52372.1| (U32435) RGS5 [Rattus norvegicus]
Length = 67
Score = 124 bits (309), Expect = 5e-28
Identities = 60/67 (89%), Positives = 64/67 (94%)
Query: 95 IACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMA 154
+ACE+YKKIKSP KMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPS SFD+A
Sbjct: 1 VACENYKKIKSPIKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSPHSFDLA 60
Query: 155 QKRIHAL 161
QKRI+AL
Sbjct: 61 QKRIYAL 67
>gb|AAD53050.1| (AF139872) regulator of G-protein signalling 5 [Sus scrofa]
Length = 67
Score = 123 bits (305), Expect = 2e-27
Identities = 59/67 (88%), Positives = 65/67 (96%)
Query: 95 IACEDYKKIKSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMA 154
+ACEDYKKIKSP KMAEKAK+IYEEFIQ+EAPKEVNIDHFTK+ITMKNLVEPS SSFD+A
Sbjct: 1 MACEDYKKIKSPVKMAEKAKKIYEEFIQSEAPKEVNIDHFTKEITMKNLVEPSPSSFDVA 60
Query: 155 QKRIHAL 161
QKRI+AL
Sbjct: 61 QKRIYAL 67
>gb|AAD45947.1|AF151967_1 (AF151967) RGS protein Gz-GAP [Gallus gallus]
Length = 218
Score = 122 bits (304), Expect = 2e-27
Identities = 58/137 (42%), Positives = 92/137 (66%), Gaps = 4/137 (2%)
Query: 45 EKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIK 104
E PA T L+E W S DKL+ G +F+ FL++EFSEEN+ FW+ACE+ K+
Sbjct: 77 ESPAPT----LEEVNAWAQSFDKLMLTPAGRNAFREFLRTEFSEENMLFWMACEELKQES 132
Query: 105 SPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEK 164
+ + + EKA+ IYE++I +PKEV++D +++ +N++EPS +FD AQ +I+ LM +
Sbjct: 133 NKSVIEEKARLIYEDYISILSPKEVSLDSRVREVINRNMLEPSQHTFDDAQLQIYTLMHR 192
Query: 165 DSLPRFVRSEFYQELIK 181
DS PRF+ S Y++L++
Sbjct: 193 DSYPRFMNSAIYKDLLR 209
>gb|AAD45948.1|AF151968_1 (AF151968) RGS protein RGS-17 [Gallus gallus]
Length = 210
Score = 122 bits (303), Expect = 3e-27
Identities = 54/131 (41%), Positives = 89/131 (67%)
Query: 51 QKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 110
Q + DE L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ +
Sbjct: 71 QNPTADEILSWAQNFDKMMKTPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIE 130
Query: 111 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 170
EKA+ IYE++I +PKEV++D +++ +NL++PS ++ AQ +I+ LM +DS PRF
Sbjct: 131 EKARLIYEDYISILSPKEVSLDSRVREVINRNLLDPSPHMYEDAQLQIYTLMHRDSFPRF 190
Query: 171 VRSEFYQELIK 181
+ S+ Y+ L++
Sbjct: 191 LNSQIYKSLVE 201
>ref|NP_003693.1| regulator of Gz-selective protein signaling [Homo sapiens]
gb|AAC62009.1| (AF060877) Gz-selective GTPase-activating protein [Homo sapiens]
gb|AAC62013.1| (AF074979) regulator of G protein signaling [Homo sapiens]
Length = 217
Score = 121 bits (300), Expect = 6e-27
Identities = 60/137 (43%), Positives = 90/137 (64%), Gaps = 4/137 (2%)
Query: 45 EKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIK 104
E PA T L+E W S DKL+ G +F+ FL++EFSEEN+ FW+ACE+ KK
Sbjct: 76 ESPAPT----LEEVNAWAQSFDKLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKKEA 131
Query: 105 SPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEK 164
+ + EKA+ IYE++I +PKEV++D +++ +N+VEPS FD AQ +I+ LM +
Sbjct: 132 NKNIIEEKARIIYEDYISILSPKEVSLDSRVREVINRNMVEPSQHIFDDAQLQIYTLMHR 191
Query: 165 DSLPRFVRSEFYQELIK 181
DS PRF+ S Y++L++
Sbjct: 192 DSYPRFMNSAVYKDLLQ 208
>sp|P79348|RGSX_BOVIN RETINA SPECIFIC REGULATOR OF G-PROTEIN SIGNALING (RET-RGS1)
gb|AAC48721.1| (U89254) retina specific RGS protein [Bos taurus]
Length = 374
Score = 121 bits (300), Expect = 6e-27
Identities = 56/128 (43%), Positives = 88/128 (68%)
Query: 54 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 113
+L+EA W S DKL+ G +F+ FL++EFSEEN+ FW+ACE+ KK + A + EKA
Sbjct: 238 TLEEASAWAQSFDKLMLTPAGRNAFREFLRTEFSEENMLFWMACEELKKEANKATIEEKA 297
Query: 114 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 173
+ IYE++I +PKEV++D ++ +++ EPS + FD AQ +I+ LM +DS PRF+ S
Sbjct: 298 RIIYEDYISILSPKEVSLDSRVRETINRSMAEPSRNIFDDAQLQIYTLMHRDSYPRFMNS 357
Query: 174 EFYQELIK 181
Y++L++
Sbjct: 358 ALYKDLLR 365
>ref|NP_064342.1| regulator of G-protein signaling 17; regulator of G-protein
signaling Z2 [Mus musculus]
gb|AAF05758.1|AF191555_1 (AF191555) regulator of G-protein signaling Z2 [Mus musculus]
Length = 210
Score = 120 bits (297), Expect = 1e-26
Identities = 52/131 (39%), Positives = 88/131 (66%)
Query: 51 QKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 110
Q + DE L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ +
Sbjct: 71 QNPTADEVLSWSQNFDKMMKTPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKAVE 130
Query: 111 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 170
EKA+ IYE++I +PKEV++D +++ ++L++PS ++ AQ +I+ LM +DS PRF
Sbjct: 131 EKARMIYEDYISILSPKEVSLDSRVREVINRSLLDPSPHMYEDAQLQIYTLMHRDSFPRF 190
Query: 171 VRSEFYQELIK 181
+ S+ Y+ ++
Sbjct: 191 LNSQIYKAFVE 201
>pir||T13580 hypothetical protein 52C10.2 - fruit fly (Drosophila melanogaster)
emb|CAA22951.1| (AL035311) 1-evidence=predicted by
content~1-method=genefinder;084~1-method_score=42.68~1-
evidence_end~2-evidence=predicted by
match~2-match_accession=SWISS-PROT:P49795~2-
match_description=G-ALPHA INTERACTING PROTEIN (GAIP
PROTEIN).~2-match_species=HOM>
Length = 244
Score = 120 bits (297), Expect = 1e-26
Identities = 54/119 (45%), Positives = 84/119 (70%)
Query: 51 QKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 110
++ +L+E W S DKL+++ G F++FL+SEFSEEN+ FW+ACED KK SP +
Sbjct: 126 EQPTLEEIRSWGKSFDKLMKSTAGRKVFQNFLRSEFSEENILFWLACEDLKKENSPELVE 185
Query: 111 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPR 169
EKA+ IYE++I +P+EV++D ++I +N++EP+ +FD AQ +I+ LM +DS PR
Sbjct: 186 EKARLIYEDYISILSPREVSLDSRVREIVNRNMIEPTTHTFDEAQIQIYTLMHRDSYPR 244
>gb|AAF33236.1|AF220159_1 (AF220159) RGS-1 [Caenorhabditis elegans]
Length = 201
Score = 118 bits (294), Expect = 3e-26
Identities = 56/137 (40%), Positives = 87/137 (62%)
Query: 44 PEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKI 103
P++ + + S + W+ S D L+ G F FLKSE+S+EN+ FW ACE+ K+
Sbjct: 21 PQRSVQPEALSYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSEYSDENILFWQACEELKRE 80
Query: 104 KSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALME 163
K+ KM EKA+ IYE+FI +PKEV++D ++I N+ P+ ++F+ AQ +I+ LM
Sbjct: 81 KNSEKMEEKARIIYEDFISILSPKEVSLDSKVREIVNTNMSRPTQNTFEDAQHQIYQLMA 140
Query: 164 KDSLPRFVRSEFYQELI 180
+DS PRF+ S FY+E +
Sbjct: 141 RDSYPRFLTSIFYRETL 157
>sp|P34295|YKO7_CAEEL HYPOTHETICAL 29.5 KD PROTEIN C05B5.7 IN CHROMOSOME III
emb|CAA83595.1| (Z32679) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=197.2,
E-value=8.5e-56, N=1 [Caenorhabditis elegans]
Length = 254
Score = 118 bits (294), Expect = 3e-26
Identities = 56/137 (40%), Positives = 87/137 (62%)
Query: 44 PEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKI 103
P++ + + S + W+ S D L+ G F FLKSE+S+EN+ FW ACE+ K+
Sbjct: 21 PQRSVQPEALSYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSEYSDENILFWQACEELKRE 80
Query: 104 KSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALME 163
K+ KM EKA+ IYE+FI +PKEV++D ++I N+ P+ ++F+ AQ +I+ LM
Sbjct: 81 KNSEKMEEKARIIYEDFISILSPKEVSLDSKVREIVNTNMSRPTQNTFEDAQHQIYQLMA 140
Query: 164 KDSLPRFVRSEFYQELI 180
+DS PRF+ S FY+E +
Sbjct: 141 RDSYPRFLTSIFYRETL 157
>pir||S43576 C05B5.7 protein (clone C05B5) - Caenorhabditis elegans
Length = 251
Score = 118 bits (294), Expect = 3e-26
Identities = 56/137 (40%), Positives = 87/137 (62%)
Query: 44 PEKPAKTQKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKI 103
P++ + + S + W+ S D L+ G F FLKSE+S+EN+ FW ACE+ K+
Sbjct: 18 PQRSVQPEALSYEMVYSWQQSFDTLMSFKSGQKCFAEFLKSEYSDENILFWQACEELKRE 77
Query: 104 KSPAKMAEKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALME 163
K+ KM EKA+ IYE+FI +PKEV++D ++I N+ P+ ++F+ AQ +I+ LM
Sbjct: 78 KNSEKMEEKARIIYEDFISILSPKEVSLDSKVREIVNTNMSRPTQNTFEDAQHQIYQLMA 137
Query: 164 KDSLPRFVRSEFYQELI 180
+DS PRF+ S FY+E +
Sbjct: 138 RDSYPRFLTSIFYRETL 154
>ref|XP_004378.1| regulator of G-protein signalling 17 [Homo sapiens]
Length = 210
Score = 118 bits (293), Expect = 4e-26
Identities = 51/131 (38%), Positives = 88/131 (66%)
Query: 51 QKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 110
Q + +E L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ +
Sbjct: 71 QNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIE 130
Query: 111 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 170
EKA+ IYE++I +PKEV++D +++ +NL++P+ ++ AQ +I+ LM +DS PRF
Sbjct: 131 EKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRF 190
Query: 171 VRSEFYQELIK 181
+ S+ Y+ ++
Sbjct: 191 LNSQIYKSFVE 201
>ref|NP_036551.2| regulator of G-protein signalling 17 [Homo sapiens]
gb|AAF08978.2|AF202257_1 (AF202257) regulator of G-protein signaling 17 [Homo sapiens]
Length = 208
Score = 118 bits (293), Expect = 4e-26
Identities = 51/131 (38%), Positives = 88/131 (66%)
Query: 51 QKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 110
Q + +E L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ +
Sbjct: 71 QNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIE 130
Query: 111 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 170
EKA+ IYE++I +PKEV++D +++ +NL++P+ ++ AQ +I+ LM +DS PRF
Sbjct: 131 EKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRF 190
Query: 171 VRSEFYQELIK 181
+ S+ Y+ ++
Sbjct: 191 LNSQIYKSFVE 201
>emb|CAB65995.1| (AL080276) dJ101K10.2 (regulator of G-protein signaling 17 (RGS17)
(RGSZ2)) [Homo sapiens]
Length = 218
Score = 118 bits (293), Expect = 4e-26
Identities = 51/131 (38%), Positives = 88/131 (66%)
Query: 51 QKTSLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMA 110
Q + +E L W + DK+++ G F+ FL++E+SEENL FW+ACED KK ++ +
Sbjct: 79 QNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEYSEENLLFWLACEDLKKEQNKKVIE 138
Query: 111 EKAKQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRF 170
EKA+ IYE++I +PKEV++D +++ +NL++P+ ++ AQ +I+ LM +DS PRF
Sbjct: 139 EKARMIYEDYISILSPKEVSLDSRVREVINRNLLDPNPHMYEDAQLQIYTLMHRDSFPRF 198
Query: 171 VRSEFYQELIK 181
+ S+ Y+ ++
Sbjct: 199 LNSQIYKSFVE 209
>gb|AAF05757.1|AF191554_1 (AF191554) regulator of G-protein signaling Z1 [Mus musculus]
Length = 239
Score = 117 bits (291), Expect = 7e-26
Identities = 53/127 (41%), Positives = 86/127 (66%)
Query: 54 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 113
+L+E W S D L+ G +F+ FL++EFSEEN+ FW+ACE+ K+ + + + EKA
Sbjct: 103 TLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREANKSTIEEKA 162
Query: 114 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 173
+ IYE++I +PKEV++D +++ +N+V+PS FD AQ +I+ LM +DS PRF+ S
Sbjct: 163 RIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQIYTLMHRDSYPRFMNS 222
Query: 174 EFYQELI 180
Y++L+
Sbjct: 223 TVYKDLL 229
>ref|NP_067349.1| regulator of G-protein signaling Z1 [Mus musculus]
gb|AAF05756.1|AF191552_1 (AF191552) regulator of G-protein signaling Z1 [Mus musculus]
Length = 239
Score = 117 bits (291), Expect = 7e-26
Identities = 53/127 (41%), Positives = 86/127 (66%)
Query: 54 SLDEALQWRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKA 113
+L+E W S D L+ G +F+ FL++EFSEEN+ FW+ACE+ K+ + + + EKA
Sbjct: 103 TLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENMLFWMACEELKREANKSTIEEKA 162
Query: 114 KQIYEEFIQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRS 173
+ IYE++I +PKEV++D +++ +N+V+PS FD AQ +I+ LM +DS PRF+ S
Sbjct: 163 RIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQIYTLMHRDSYPRFMNS 222
Query: 174 EFYQELI 180
Y++L+
Sbjct: 223 TVYKDLL 229
>pir||T21035 hypothetical protein F16H9.1b - Caenorhabditis elegans
emb|CAB54219.1| (Z50005) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1 [Caenorhabditis elegans]
emb|CAB54230.1| (Z67882) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1 [Caenorhabditis elegans]
Length = 181
Score = 113 bits (281), Expect = 1e-24
Identities = 52/120 (43%), Positives = 80/120 (66%)
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
W S + L+++ G F FLK E+S+EN+ FW ACE+ K+ K+ K+ EKA+ IYE+F
Sbjct: 52 WSQSFENLMKHRAGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDF 111
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
I +PKEV++D ++I N+ PS S+FD AQ +I+ LM++DS PRF+ S Y+ ++
Sbjct: 112 ISILSPKEVSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKTVM 171
>sp|P49808|YUE1_CAEEL HYPOTHETICAL 19.6 KDA PROTEIN F16H9.1 IN CHROMOSOME X
pir||T21034 hypothetical protein F16H9.1a - Caenorhabditis elegans
emb|CAA90295.1| (Z50005) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1~cDNA EST yk78b5.5 comes from this
gene~cDNA EST yk78b5.3 comes from this gene~cDNA EST
yk512h4.5 comes from this gene [Cae>
emb|CAA91803.1| (Z67882) contains similarity to Pfam domain: PF00615 (Regulator of
G protein signaling domain), Score=200.4,
E-value=9.1e-57, N=1~cDNA EST yk78b5.5 comes from this
gene~cDNA EST yk78b5.3 comes from this gene~cDNA EST
yk512h4.5 comes from this gene [Cae>
gb|AAF33782.1|AF220265_1 (AF220265) RGS-2 [Caenorhabditis elegans]
Length = 169
Score = 113 bits (281), Expect = 1e-24
Identities = 52/120 (43%), Positives = 80/120 (66%)
Query: 61 WRDSLDKLLQNNYGLASFKSFLKSEFSEENLEFWIACEDYKKIKSPAKMAEKAKQIYEEF 120
W S + L+++ G F FLK E+S+EN+ FW ACE+ K+ K+ K+ EKA+ IYE+F
Sbjct: 40 WSQSFENLMKHRAGQKYFAEFLKGEYSDENILFWQACEELKREKNAEKIEEKARIIYEDF 99
Query: 121 IQTEAPKEVNIDHFTKDITMKNLVEPSLSSFDMAQKRIHALMEKDSLPRFVRSEFYQELI 180
I +PKEV++D ++I N+ PS S+FD AQ +I+ LM++DS PRF+ S Y+ ++
Sbjct: 100 ISILSPKEVSLDSRVREIVNTNMGRPSASTFDEAQNQIYTLMQRDSYPRFLASNIYKTVM 159
Database: nr
Number of letters in database: 189,012,571
Number of sequences in database: 598,029
Lambda K H
0.315 0.132 0.374
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 64859583
Number of Sequences: 598029
Number of extensions: 2493540
Number of successful extensions: 7905
Number of sequences better than 10.0: 205
Number of HSP's better than 10.0 without gapping: 161
Number of HSP's successfully gapped in prelim test: 44
Number of HSP's that attempted gapping in prelim test: 7622
Number of HSP's gapped (non-prelim): 212
length of query: 181
length of database: 189,012,571
effective HSP length: 57
effective length of query: 124
effective length of database: 154,924,918
effective search space: 19210689832
effective search space used: 19210689832
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 68 (30.9 bits)
