Score E
Sequences producing significant alignments: (bits) Value
sp|P56199|ITA1_HUMAN INTEGRIN ALPHA-1 (LAMININ AND COLLAGEN... 2297 0.0
sp|P18614|ITA1_RAT INTEGRIN ALPHA-1 PRECURSOR (LAMININ AND ... 2049 0.0
dbj|BAA23160.1| (AB000470) alpha1 integrin [Gallus gallus] 1638 0.0
ref|NP_002194.1| integrin alpha 2 precursor; Integrin, alph... 817 0.0
gb|AAF01258.1|AF109681_1 (AF109681) integrin alpha-11 subun... 810 0.0
ref|NP_036343.1| integrin, alpha 11 [Homo sapiens] >gi|5915... 807 0.0
sp|P53710|ITA2_BOVIN PLATELET MEMBRANE GLYCOPROTEIN IA PREC... 796 0.0
ref|NP_032422.1| integrin alpha 2 (Cd49b); VLA-2 receptor, ... 793 0.0
gb|AAF21944.1|AF112345_1 (AF112345) integrin alpha 10 subun... 700 0.0
ref|NP_003628.1| integrin, alpha 10 [Homo sapiens] >gi|3420... 696 0.0
sp|Q90615|ITA1_CHICK INTEGRIN ALPHA-1 (LAMININ AND COLLAGEN... 483 e-135
pir||A55348 integrin alpha-1 - chicken (fragment) 455 e-126
gb|AAF61638.1|AF172723_1 (AF172723) integrin alpha 10 subun... 451 e-125
gb|AAA69770.1| (L43058) integrin alpha 2 subunit [Xenopus l... 432 e-119
emb|CAA53178.1| (X75427) alpha 2 integrin [Mus musculus] 399 e-109
pdb|1QC5|A Chain A, I Domain From Integrin Alpha1-Beta1 378 e-103
pdb|1QC5|B Chain B, I Domain From Integrin Alpha1-Beta1 376 e-102
ref|NP_000623.1| integrin alpha M; antigen CD11b (p170); m... 376 e-102
sp|P11215|ITAM_HUMAN CELL SURFACE GLYCOPROTEIN MAC-1 ALPHA ... 375 e-102
gb|AAA59903.1| (J04145) neutrophil adherence receptor alpha... 372 e-102
pir||RWHU1B cell surface glycoprotein CD11b precursor - hum... 372 e-102
pdb|1CK4|B Chain B, Crystal Structure Of Rat A1b1 Integrin ... 368 e-100
sp|P20701|ITAL_HUMAN LEUKOCYTE ADHESION GLYCOPROTEIN LFA-1 ... 365 1e-99
ref|NP_002200.1| integrin alpha L precursor; antigen CD11A ... 365 2e-99
ref|NP_032427.1| integrin alpha M (Cd11b); Mac-1 alpha; CD1... 362 1e-98
gb|AAC31672.1| (AC002310) leukocyte function-associated mol... 360 7e-98
pir||RWHU1C cell surface glycoprotein CD11c precursor - human 358 2e-97
gb|AAF21241.1|AF021334_1 (AF021334) alpha D integrin [Rattu... 358 3e-97
ref|NP_000878.1| integrin alpha X precursor [Homo sapiens] ... 357 3e-97
gb|AAF81280.1| (AF268593) integrin beta 2 alpha subunit; CD... 353 9e-96
gb|AAA51620.1| (M29487) integrin alpha subunit precursor [H... 349 1e-94
gb|AAB38547.1| (U37028) leukointegrin alpha d chain [Homo s... 347 4e-94
gb|AAD25885.1|AF065902_1 (AF065902) integrin alpha L [Mus m... 339 8e-92
ref|NP_067309.1| integrin alpha X (Cd11c); integrin aX; CD1... 339 1e-91
sp|P24063|ITAL_MOUSE LEUKOCYTE ADHESION GLYCOPROTEIN LFA-1 ... 339 1e-91
gb|AAD25884.1|AF065901_1 (AF065901) integrin alpha L [Mus m... 335 1e-90
gb|AAB16869.1| (U40072) CD11b [Sus scrofa] 333 8e-90
gb|AAC23662.1| (AF020045) integrin alpha E1 [Rattus norvegi... 290 6e-77
ref|NP_032425.1| integrin, alpha E, epithelial-associated [... 289 1e-76
gb|AAC23663.1| (AF020046) integrin alpha E2 [Rattus norvegi... 288 2e-76
gb|AAF43107.1| (AF168787) HUMINAE [Homo sapiens] 287 4e-76
gb|AAD30063.1| (AF133085) Itgae protein [Mus sp.] 286 7e-76
ref|NP_002199.2| integrin, alpha E (antigen CD103, human mu... 285 2e-75
pir||A53213 integrin alpha-E chain - human 285 2e-75
pir||A49459 integrin alpha-9 chain - human 231 3e-59
sp|Q13797|ITA9_HUMAN INTEGRIN ALPHA-9 PRECURSOR (INTEGRIN A... 231 3e-59
gb|AAA16099.1| (L24158) integrin alpha 9 protein [Homo sapi... 231 3e-59
ref|NP_034706.1| integrin alpha 4 (Cd49d); VLA-4 receptor, ... 226 1e-57
sp|Q00651|ITA4_MOUSE INTEGRIN ALPHA-4 PRECURSOR (INTEGRIN A... 226 1e-57
gb|AAD22567.1|U22152_1 (U22152) alpha-Lv1 integrin [Lytechi... 224 4e-57
>sp|P56199|ITA1_HUMAN INTEGRIN ALPHA-1 (LAMININ AND COLLAGEN RECEPTOR) (VLA-1) (CD49A)
pir||A45226 integrin alpha 1 subunit - human (fragment)
Length = 1151
Score = 2297 bits (5888), Expect = 0.0
Identities = 1133/1151 (98%), Positives = 1133/1151 (98%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE
Sbjct: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC
Sbjct: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
Query: 121 SDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQ 180
SDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQ
Sbjct: 121 SDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQ 180
Query: 181 VGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGA 240
VGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGA
Sbjct: 181 VGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGA 240
Query: 241 RRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIK 300
RRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIK
Sbjct: 241 RRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIK 300
Query: 301 SIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQ 360
SIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQ
Sbjct: 301 SIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQ 360
Query: 361 DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSG 420
DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSG
Sbjct: 361 DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSG 420
Query: 421 DVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDIL 480
DVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDIL
Sbjct: 421 DVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDIL 480
Query: 481 LVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCG 540
LVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCG
Sbjct: 481 LVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCG 540
Query: 541 ARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGK 600
ARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGK
Sbjct: 541 ARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGK 600
Query: 601 TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNC 660
TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNC
Sbjct: 601 TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNC 660
Query: 661 HMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRN 720
HMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRN
Sbjct: 661 HMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRN 720
Query: 721 ITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDC 780
ITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDC
Sbjct: 721 ITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDC 780
Query: 781 GNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFS 840
GNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFS
Sbjct: 781 GNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFS 840
Query: 841 GIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEE 900
GIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEE
Sbjct: 841 GIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEE 900
Query: 901 PPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYL 960
PPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYL
Sbjct: 901 PPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYL 960
Query: 961 IRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMT 1020
IRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMT
Sbjct: 961 IRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMT 1020
Query: 1021 TSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGE 1080
TSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGE
Sbjct: 1021 TSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGE 1080
Query: 1081 LRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGF 1140
LRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVI WKIGF
Sbjct: 1081 LRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKIGF 1140
Query: 1141 FKRPLKKKMEK 1151
FKRPLKKKMEK
Sbjct: 1141 FKRPLKKKMEK 1151
>sp|P18614|ITA1_RAT INTEGRIN ALPHA-1 PRECURSOR (LAMININ AND COLLAGEN RECEPTOR) (VLA-1)
(CD49A)
pir||A35854 integrin alpha-1 chain precursor - rat
emb|CAA36384.1| (X52140) precursor polypeptide (AA -28 to 1152) [Rattus norvegicus]
Length = 1180
Score = 2049 bits (5250), Expect = 0.0
Identities = 1000/1153 (86%), Positives = 1069/1153 (91%), Gaps = 3/1153 (0%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FNVDVKNSM+FSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPK RTGDVYKCPVGR
Sbjct: 29 FNVDVKNSMSFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKARTGDVYKCPVGRER 88
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
++PCVKLDLPVNTSIPNVTE+KENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC
Sbjct: 89 AMPCVKLDLPVNTSIPNVTEIKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 148
Query: 121 SDVSPTFQVVNSIAPVQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQ 180
SDVSPTFQVVNS APVQECSTQLDIVIVLDGSNSIYPW+SV AFLNDLLKRMDIGPKQTQ
Sbjct: 149 SDVSPTFQVVNSFAPVQECSTQLDIVIVLDGSNSIYPWESVIAFLNDLLKRMDIGPKQTQ 208
Query: 181 VGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGA 240
VGIVQYGENVTHEFNLNKYSSTEEVLVAA KI ++GG QTMTALG DTARKEAFTEARGA
Sbjct: 209 VGIVQYGENVTHEFNLNKYSSTEEVLVAANKIGRQGGLQTMTALGIDTARKEAFTEARGA 268
Query: 241 RRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIK 300
RRGVKKVMVIVTDGESHDN+RLK+VIQDCEDENIQRFSIAILG YNRGNLSTEKFVEEIK
Sbjct: 269 RRGVKKVMVIVTDGESHDNYRLKQVIQDCEDENIQRFSIAILGHYNRGNLSTEKFVEEIK 328
Query: 301 SIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQ 360
SIASEPTEKHFFNVSDELALVTIVK LGERIFALEATADQSAASFEMEMSQTGFSAHYSQ
Sbjct: 329 SIASEPTEKHFFNVSDELALVTIVKALGERIFALEATADQSAASFEMEMSQTGFSAHYSQ 388
Query: 361 DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSG 420
DWVMLGAVGAYDWNGTVVMQKA+Q++IP NTTF E K NEPLASYLGYTVNSAT G
Sbjct: 389 DWVMLGAVGAYDWNGTVVMQKANQMVIPHNTTFQTEPAKMNEPLASYLGYTVNSATIP-G 447
Query: 421 DVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDIL 480
DVLYIAGQPRYNHTGQV+IY+MEDGNI ILQTL GEQIGSYFGS+LTT DIDKDS TD+L
Sbjct: 448 DVLYIAGQPRYNHTGQVVIYKMEDGNINILQTLGGEQIGSYFGSVLTTIDIDKDSYTDLL 507
Query: 481 LVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCG 540
LVGAPMYMGTEKEEQGKVYVYA+NQTRFEYQMSLEPI+QTCCSS + NSCT ENKNEPCG
Sbjct: 508 LVGAPMYMGTEKEEQGKVYVYAVNQTRFEYQMSLEPIRQTCCSSLKDNSCTKENKNEPCG 567
Query: 541 ARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGK 600
ARFGTAIAAVKDLN+DGFND+VIGAPLEDDH GAVYIYHGSGKTIR+ YAQRIPSGGDGK
Sbjct: 568 ARFGTAIAAVKDLNVDGFNDVVIGAPLEDDHAGAVYIYHGSGKTIREAYAQRIPSGGDGK 627
Query: 601 TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNC 660
TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFW+RDVAVVKVTMNFEPNKVNIQKKNC
Sbjct: 628 TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWARDVAVVKVTMNFEPNKVNIQKKNC 687
Query: 661 HMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRN 720
+EGKETVCINAT+CF VKLKSKED+IYEADLQYRVTLDSLRQISRSFFSGTQERK+QRN
Sbjct: 688 RVEGKETVCINATMCFHVKLKSKEDSIYEADLQYRVTLDSLRQISRSFFSGTQERKIQRN 747
Query: 721 ITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDC 780
ITVR+SEC +HSFYMLDKHDFQDSVR+TLDFNLTDPENGPVLDD+LPNSVHE+IPFAKDC
Sbjct: 748 ITVRESECIRHSFYMLDKHDFQDSVRVTLDFNLTDPENGPVLDDALPNSVHEHIPFAKDC 807
Query: 781 GNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFS 840
GNKE+CISDL+L+V+TTEK LLIV+SQ+DKFNVSLTVKN DSAYNTRT+V +SPNL+FS
Sbjct: 808 GNKERCISDLTLNVSTTEKSLLIVKSQHDKFNVSLTVKNKGDSAYNTRTVVQHSPNLIFS 867
Query: 841 GIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEE 900
GIE IQKDSCESN NITC+VGYPFLR GE VTFKI+FQFNTS+L EN I+LSATSDSEE
Sbjct: 868 GIEEIQKDSCESNQNITCRVGYPFLRAGETVTFKIIFQFNTSHLSENAIIHLSATSDSEE 927
Query: 901 PPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYL 960
P E+L+DN VNISIPVKYEVGLQFYSSASE+HIS+AANET+PE INSTEDIGNEIN+FY
Sbjct: 928 PLESLNDNEVNISIPVKYEVGLQFYSSASEHHISVAANETIPEFINSTEDIGNEINVFYT 987
Query: 961 IRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMT 1020
IRK G FPMPEL+LSISFPN+T++GYPVLYP G SSS+N NCRP EDPF INSGKKMT
Sbjct: 988 IRKRGHFPMPELQLSISFPNLTADGYPVLYPIGWSSSDNVNCRPRSLEDPFGINSGKKMT 1047
Query: 1021 TS-TDHLKRGTILDC-NTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIR 1078
S ++ LKRGTI DC +TC ATITC+L SD+SQVNVSL+LWKPTFI+++FSSLNLT+R
Sbjct: 1048 ISKSEVLKRGTIQDCSSTCGVATITCSLLPSDLSQVNVSLLLWKPTFIRAHFSSLNLTLR 1107
Query: 1079 GELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKI 1138
GEL+SEN+SL LSSSN+KRELAIQISKDGLPGRVPLWVI WKI
Sbjct: 1108 GELKSENSSLTLSSSNRKRELAIQISKDGLPGRVPLWVILLSAFAGLLLLMLLILALWKI 1167
Query: 1139 GFFKRPLKKKMEK 1151
GFFKRPLKKKMEK
Sbjct: 1168 GFFKRPLKKKMEK 1180
>dbj|BAA23160.1| (AB000470) alpha1 integrin [Gallus gallus]
Length = 1171
Score = 1638 bits (4194), Expect = 0.0
Identities = 806/1156 (69%), Positives = 936/1156 (80%), Gaps = 9/1156 (0%)
Query: 2 NVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGES 61
NVDVKN+MTFSGP+EDMFGYTVQQYENEEGKWVLIGSPLVGQP+ RTGDVYKCPVGR
Sbjct: 19 NVDVKNAMTFSGPLEDMFGYTVQQYENEEGKWVLIGSPLVGQPEKRTGDVYKCPVGRDSQ 78
Query: 62 LPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGICS 121
PC+KL+LP TS+PNV EVKENMT G+TLVTNP GGFLACGPLYAY+CG LHYTTG+CS
Sbjct: 79 SPCIKLNLPDATSVPNVMEVKENMTLGTTLVTNPKGGFLACGPLYAYKCGRLHYTTGVCS 138
Query: 122 DVSPTFQVVNSIAP-VQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQ 180
+VS TF+ V ++AP VQEC TQLDIVIVLDGSNSIYPW+SVTAFLN LL+ MDIGP+QTQ
Sbjct: 139 NVSSTFETVKAVAPSVQECKTQLDIVIVLDGSNSIYPWESVTAFLNSLLRNMDIGPQQTQ 198
Query: 181 VGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGA 240
VGIVQYG+ V HEF LN YS+TEEV+ AA +I QRGG QTMTALG DTAR+EAFTEA GA
Sbjct: 199 VGIVQYGQTVVHEFYLNTYSTTEEVMDAALRIRQRGGTQTMTALGIDTAREEAFTEAHGA 258
Query: 241 RRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIK 300
RRGV+KVMVIVTDGESHDN+RL++VI CEDENIQRF+IAILGSY+RGNLSTEKFVEEIK
Sbjct: 259 RRGVQKVMVIVTDGESHDNYRLQEVIDKCEDENIQRFAIAILGSYSRGNLSTEKFVEEIK 318
Query: 301 SIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQ 360
SIAS+PTEKHFFNVSDELALVTIV+ LGERIFALEAT DQ AASFEMEMSQ GFSAHYSQ
Sbjct: 319 SIASKPTEKHFFNVSDELALVTIVEALGERIFALEATTDQQAASFEMEMSQAGFSAHYSQ 378
Query: 361 DWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSG 420
DWVMLGAVGAYDWNGTVVM K S I IP N TF ++K EPLA+YLGYTVNSA + G
Sbjct: 379 DWVMLGAVGAYDWNGTVVMVKDSDISIPSNDTFRDRHSEKIEPLAAYLGYTVNSA-LTPG 437
Query: 421 DVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDIL 480
VLYIAGQPRYNHTGQVIIY+ME +K+LQ L GEQIGSYFG ++TT DI++DS TD+L
Sbjct: 438 GVLYIAGQPRYNHTGQVIIYKMEGREVKVLQRLKGEQIGSYFGGVITTIDINRDSFTDLL 497
Query: 481 LVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCG 540
LVGAP YMGTEKEEQGKVYVYALN+T+FEYQMSLEPIKQTCCS +H++C KNEPCG
Sbjct: 498 LVGAPTYMGTEKEEQGKVYVYALNKTKFEYQMSLEPIKQTCCSPLKHDTCKV-LKNEPCG 556
Query: 541 ARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGK 600
ARFGTAIAAVKDLNLDG+NDIVIG+PLEDDH GAVYIYHG G TI K+Y QRI SGGDG+
Sbjct: 557 ARFGTAIAAVKDLNLDGYNDIVIGSPLEDDHRGAVYIYHGHGNTISKKYTQRIASGGDGE 616
Query: 601 TLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNC 660
+KFFGQS+HGEMDLN DGL DVTIGGLGGAALFWSRDVA V V+M F P +NIQ++NC
Sbjct: 617 KVKFFGQSVHGEMDLNDDGLIDVTIGGLGGAALFWSRDVAEVNVSMQFMPKSINIQQQNC 676
Query: 661 HMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRN 720
+ ++T+CINAT+CF+ +LKSKED I+E+ LQY +TLD+ RQISRS F+ T ERK+Q+N
Sbjct: 677 QINKRKTICINATICFKTRLKSKED-IFESSLQYWITLDAQRQISRSLFTETHERKMQKN 735
Query: 721 ITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDC 780
IT++ SEC KH+FYMLDK DFQDSV++ L+FN +DPE+GPVLD +LPNS+ EYIPF KDC
Sbjct: 736 ITIKGSECIKHNFYMLDKPDFQDSVKVLLEFNFSDPESGPVLDSNLPNSISEYIPFTKDC 795
Query: 781 GNKEKCISDLSLHV----ATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPN 836
G K KCISDL+L+V A IV+S+ND+F + L++KN KDSAYNTR +V YSPN
Sbjct: 796 GAKNKCISDLALNVKASIAGDSSSPFIVKSRNDRFTIQLSIKNKKDSAYNTRALVQYSPN 855
Query: 837 LVFSGIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATS 896
++F+GIE IQKDSCESNHNITCKVGYPFL+ E ++FKI FQFN SYL+EN T+ + ATS
Sbjct: 856 IIFAGIEDIQKDSCESNHNITCKVGYPFLKPEEEISFKISFQFNASYLLENATVDVYATS 915
Query: 897 DSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEIN 956
DSEEPPETL DN ++IPVKYEVGL F S E+H+ IAANET+P IN+TE IG+E+
Sbjct: 916 DSEEPPETLRDNRGQVTIPVKYEVGLIFVSVFKEHHVIIAANETIPTAINTTEQIGDEVT 975
Query: 957 IFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSG 1016
+ Y I K FPMP L L I +P++T+ +LY T LS S+NA C+ D I SG
Sbjct: 976 LHYRIEKGEHFPMPNLTLQILYPDVTTAKNTLLYITTLSHSQNAICKSSYPVDHLKIGSG 1035
Query: 1017 KK-MTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNL 1075
K + + TI++C+T A+I C L SDISQVNVSL +WKPT IK+ SL L
Sbjct: 1036 KSYVLPKIKEPTKDTIMECDTFSCASINCALAPSDISQVNVSLRVWKPTIIKASIHSLTL 1095
Query: 1076 TIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXX 1135
++ LRSEN+SL+L + +QK E I+ISK+ PG VPLWVI
Sbjct: 1096 VVKALLRSENSSLILRNDHQKLETMIKISKEPPPGSVPLWVIPLSIFAGLLILALLIFAL 1155
Query: 1136 WKIGFFKRPLKKKMEK 1151
WK GFFKRPLKKKMEK
Sbjct: 1156 WKAGFFKRPLKKKMEK 1171
>ref|NP_002194.1| integrin alpha 2 precursor; Integrin, alpha-2 (CD49B; alpha-2 subunit
of VLA-2 receptor; platelet antigen Br) [Homo sapiens]
sp|P17301|ITA2_HUMAN PLATELET MEMBRANE GLYCOPROTEIN IA PRECURSOR (GPIA) (COLLAGEN
RECEPTOR) (INTEGRIN ALPHA-2) (VLA-2 ALPHA CHAIN) (CD49B)
pir||A33998 integrin alpha-2 chain precursor - human
emb|CAA34894.1| (X17033) integrin alpha-2 preprotein (AA -29 to 1152) [Homo sapiens]
Length = 1181
Score = 817 bits (2088), Expect = 0.0
Identities = 464/1175 (39%), Positives = 678/1175 (57%), Gaps = 67/1175 (5%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
+NV + + FSGP + FGY VQQ+ N +G W+L+GSP G P+NR GDVYKCPV
Sbjct: 30 YNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPENRMGDVYKCPVDLST 89
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPN-GGFLACGPLYAYRCGHLHYTTGI 119
+ C KL+L +TSIPNVTE+K NM+ G L N GGFL CGPL+A +CG+ +YTTG+
Sbjct: 90 AT-CEKLNLQTSTSIPNVTEMKTNMSLGLILTRNMGTGGFLTCGPLWAQQCGNQYYTTGV 148
Query: 120 CSDVSPTFQVVNSIAPV-QECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQ 178
CSD+SP FQ+ S +P Q C + +D+V+V D SNSIYPWD+V FL ++ +DIGP +
Sbjct: 149 CSDISPDFQLSASFSPATQPCPSLIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTK 208
Query: 179 TQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEAR 238
TQVG++QY N FNLN Y + EE++VA + Q GG T T ARK A++ A
Sbjct: 209 TQVGLIQYANNPRVVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAAS 268
Query: 239 GARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEE 298
G RR KVMV+VTDGESHD LK VI C +NI RF IA+LG NR L T+ ++E
Sbjct: 269 GGRRSATKVMVVVTDGESHDGSMLKAVIDQCNHDNILRFGIAVLGYLNRNALDTKNLIKE 328
Query: 299 IKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY 358
IK+IAS PTE++FFNVSDE AL+ TLGE+IF++E T Q +F+MEMSQ GFSA Y
Sbjct: 329 IKAIASIPTERYFFNVSDEAALLEKAGTLGEQIFSIEGTV-QGGDNFQMEMSQVGFSADY 387
Query: 359 S--QDWVMLGAVGAYDWNGTVVMQKA-SQIIIPRNTTFNVESTKKNEPLASYLGYTVNSA 415
S D +MLGAVGA+ W+GT+V + + +I P+ + + + +SYLGY+V +A
Sbjct: 388 SSQNDILMLGAVGAFGWSGTIVQKTSHGHLIFPKQAFDQILQDRNH---SSYLGYSV-AA 443
Query: 416 TASSGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKD 474
++ ++AG PR N+TGQ+++Y + E+GNI ++Q G+QIGSYFGS+L + D+DKD
Sbjct: 444 ISTGESTHFVAGAPRANYTGQIVLYSVNENGNITVIQAHRGDQIGSYFGSVLCSVDVDKD 503
Query: 475 SNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTEN 534
+ TD+LLVGAPMYM K+E+G+VY++ + + LE + EN
Sbjct: 504 TITDVLLVGAPMYMSDLKKEEGRVYLFTIKKGILGQHQFLEGPE------------GIEN 551
Query: 535 KNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIP 594
RFG+AIAA+ D+N+DGFND+++G+PLE+ + GAVYIY+G TIR +Y+Q+I
Sbjct: 552 ------TRFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKI- 604
Query: 595 SGGDG---KTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPN 651
G DG L++FG+S+ G DLNGD +TDV+IG G WS+ +A V + +F P
Sbjct: 605 LGSDGAFRSHLQYFGRSLDGYGDLNGDSITDVSIGAFGQVVQLWSQSIADVAIEASFTPE 664
Query: 652 KVNIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLD----SLRQISRS 707
K+ + KN I +CF K + + + + Y +TLD S R SR
Sbjct: 665 KITLVNKNAQ--------IILKLCFSAKFRPTKQN-NQVAIVYNITLDADGFSSRVTSRG 715
Query: 708 FFSGTQERKVQRNITVRKSE-CTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSL 766
F ER +Q+N+ V +++ C +H Y+ + D +S+ + +D +L +P P L+
Sbjct: 716 LFKENNERCLQKNMVVNQAQSCPEHIIYIQEPSDVVNSLDLRVDISLENPGTSPALEAYS 775
Query: 767 PNSVHEYIPFAKDCGNKEKCISDLSL---HVATTEKDLLIVRSQNDKFNVSLTVKNTKDS 823
+ IPF KDCG CISDL L + ++ IV +QN + S+T+KN ++S
Sbjct: 776 ETAKVFSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQPFIVSNQNKRLTFSVTLKNKRES 835
Query: 824 AYNTRTIVHYSPNLVFSGIEAIQKDSCE-------SNHNITCKVGYPFLRRGEMVTFKIL 876
AYNT +V +S NL F+ ++ D E S ++ C VGYP L+R + VTF I
Sbjct: 836 AYNTGIVVDFSENLFFASF-SLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTIN 894
Query: 877 FQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIA 936
F FN L ++ A S+S+E E +DN+VN+ IP+ Y+ + S + I+
Sbjct: 895 FDFNLQNLQNQASLSFQALSESQE--ENKADNLVNLKIPLLYDAEIHLTRSTNINFYEIS 952
Query: 937 ANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSS 996
++ VP +++S ED+G + IF L +GS P+ + I P T P++Y TG+ +
Sbjct: 953 SDGNVPSIVHSFEDVGPKF-IFSLKVTTGSVPVSMATVIIHIPQYTKEKNPLMYLTGVQT 1011
Query: 997 SENANCRPHIFEDPFSI-NSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQ-- 1053
+ + + +P I + ++ +++ + L+C T + +TC L +
Sbjct: 1012 DKAGDISCNADINPLKIGQTSSSVSFKSENFRHTKELNCRTASCSNVTCWLKDVHMKGEY 1071
Query: 1054 -VNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRV 1112
VNV+ +W TF S F ++ LT E+ + N + + N + + I K V
Sbjct: 1072 FVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIEDNTV-TIPLMIMKPDEKAEV 1130
Query: 1113 PLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKK 1147
P VI WK+GFFKR +K
Sbjct: 1131 PTGVIIGSIIAGILLLLALVAILWKLGFFKRKYEK 1165
>gb|AAF01258.1|AF109681_1 (AF109681) integrin alpha-11 subunit precursor [Homo sapiens]
Length = 1189
Score = 810 bits (2070), Expect = 0.0
Identities = 449/1192 (37%), Positives = 682/1192 (56%), Gaps = 81/1192 (6%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + G FGYTVQQ++ KW+++G+PL +TGDVYKCPV G
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNP-NGGFLACGPLYAYRCGHLHYTTGI 119
C KL+L ++ NV+E K+NM G +L TNP + FLAC PL+++ CG +YTTG+
Sbjct: 83 ---CTKLNLG-RVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGM 138
Query: 120 CSDVSPTFQVVNSIAP-VQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQ 178
CS V+ F+ ++AP +Q C T +DIVIVLDGSNSIYPW V FL ++LK+ IGP Q
Sbjct: 139 CSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVEVQHFLINILKKFYIGPGQ 198
Query: 179 TQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEAR 238
QVG+VQYGE+V HEF+LN Y S ++V+ AA I QRGG +T TA G + AR EAF +
Sbjct: 199 IQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--K 256
Query: 239 GARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEE 298
G R+G KKVM+++TDGESHD+ L+KVIQ E +N+ R+++A+LG YNR ++ E F+ E
Sbjct: 257 GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNE 316
Query: 299 IKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY 358
IK IAS+P +KHFFNV+DE AL IV LG+RIF+LE T +++ SF +EMSQTGFS+H
Sbjct: 317 IKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT-NKNETSFGLEMSQTGFSSHV 375
Query: 359 SQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATAS 418
+D V+LGAVGAYDWNG V+ + ++ +IP ++ E ++ + +YLGYTV S +S
Sbjct: 376 VEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSS 435
Query: 419 SGDVLYIAGQPRYNHTGQVIIYRMEDG-NIKILQTLSGEQIGSYFGSILTTTDIDKDSNT 477
+Y+AG PR+NHTG+VI++ M + ++ I Q + G+QIGSYFGS +T+ DID D T
Sbjct: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
Query: 478 DILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNE 537
D+LLVGAPMY E E+GKVYVY L Q RF Y +L+ +S + +N
Sbjct: 496 DVLLVGAPMYFN-EGRERGKVYVYELRQNRFVYNGTLK------------DSHSYQN--- 539
Query: 538 PCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGG 597
ARFG++IA+V+DLN D +ND+V+GAPLED+H GA+YI+HG +I K QRI +
Sbjct: 540 ---ARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASE 596
Query: 598 DGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQK 657
L++FG SIHG++DLN DGL D+ +G LG A + WSR V + +++FEP+K+NI
Sbjct: 597 LATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFH 656
Query: 658 KNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKV 717
++C G++ C+ A +CF + ++Y T+D R R+ +R
Sbjct: 657 RDCKRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFT 716
Query: 718 QRNITVRKSE--CTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIP 775
R + + + C + +F++LD D+ V +++++L DP++GP+LDD P ++ +P
Sbjct: 717 NRAVLLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVP 776
Query: 776 FAKDCGNKEKCISDL--------------------------SLHVATTEKDLLIVRSQND 809
F C E C+ DL S + + + + I+ S
Sbjct: 777 FWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQ 836
Query: 810 KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESN----------HNITCK 859
+ V T++N ++AY+T + S NL F+ + IQK+ + + C
Sbjct: 837 RVAVEATLENRGENAYSTVLNISQSANLQFASL--IQKEDSDGSIECVNEERRLQKQVCN 894
Query: 860 VGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYE 919
V YPF R V F++ F+F+ S + ++ I L+A SDS E T DNV + +KYE
Sbjct: 895 VSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYE 954
Query: 920 VGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFP 979
+ F S+S H + N + + + IG + + I+ G FP+ + + I+ P
Sbjct: 955 ADVLFTRSSSLSHYEVKLNSS----LERYDGIGPPFSCIFRIQNLGLFPIHGIMMKITIP 1010
Query: 980 NMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKF 1039
T +G +L + E AN +I+ + ++ + T + L+R L+ +
Sbjct: 1011 IATRSGNRLLKLRDFLTDEVANTSCNIWGN----STEYRPTPVEEDLRRAPQLNHSNSDV 1066
Query: 1040 ATITCNLTSSDISQVNVSLI--LWKPTFIKSYFSSLNLTIRGEL-RSENASLVLSSSNQK 1096
+I CN+ ++N L+ LW + + S+ + + L R ++ + +
Sbjct: 1067 VSINCNIRLVPNQEINFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDPS 1126
Query: 1097 RELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKK 1148
R++ +ISK +VP+W+I WK+GFF+ +++
Sbjct: 1127 RQIVFEISKQE-DWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRR 1177
>ref|NP_036343.1| integrin, alpha 11 [Homo sapiens]
gb|AAD51919.2|AF137378_1 (AF137378) integrin alpha 11 subunit precursor [Homo sapiens]
Length = 1188
Score = 807 bits (2061), Expect = 0.0
Identities = 448/1193 (37%), Positives = 681/1193 (56%), Gaps = 84/1193 (7%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + G FGYTVQQ++ KW+++G+PL +TGDVYKCPV G
Sbjct: 23 FNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLETNGYQKTGDVYKCPVIHGN 82
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNP-NGGFLACGPLYAYRCGHLHYTTGI 119
C KL+L ++ NV+E K+NM G +L TNP + FLAC PL+++ CG +YTTG+
Sbjct: 83 ---CTKLNLG-RVTLSNVSERKDNMRLGLSLATNPKDNSFLACSPLWSHECGSSYYTTGM 138
Query: 120 CSDVSPTFQVVNSIAP-VQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQ 178
CS V+ F+ ++AP +Q C T +DIVIVLDGSNSIYPW V FL ++LK+ IGP Q
Sbjct: 139 CSRVNSNFRFSKTVAPALQRCQTYMDIVIVLDGSNSIYPWVEVQHFLINILKKFYIGPGQ 198
Query: 179 TQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEAR 238
QVG+VQYGE+V HEF+LN Y S ++V+ AA I QRGG +T TA G + AR EAF +
Sbjct: 199 IQVGVVQYGEDVVHEFHLNDYRSVKDVVEAASHIEQRGGTETRTAFGIEFARSEAFQ--K 256
Query: 239 GARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEE 298
G R+G KKVM+++TDGESHD+ L+KVIQ E +N+ R+++A+LG YNR ++ E F+ E
Sbjct: 257 GGRKGAKKVMIVITDGESHDSPDLEKVIQQSERDNVTRYAVAVLGYYNRRGINPETFLNE 316
Query: 299 IKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY 358
IK IAS+P +KHFFNV+DE AL IV LG+RIF+LE T +++ SF +EMSQTGFS+H
Sbjct: 317 IKYIASDPDDKHFFNVTDEAALKDIVDALGDRIFSLEGT-NKNETSFGLEMSQTGFSSHV 375
Query: 359 SQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATAS 418
+D V+LGAVGAYDWNG V+ + ++ +IP ++ E ++ + +YLGYTV S +S
Sbjct: 376 VEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRESYLKEFPEELKNHGAYLGYTVTSVVSS 435
Query: 419 SGDVLYIAGQPRYNHTGQVIIYRMEDG-NIKILQTLSGEQIGSYFGSILTTTDIDKDSNT 477
+Y+AG PR+NHTG+VI++ M + ++ I Q + G+QIGSYFGS +T+ DID D T
Sbjct: 436 RQGRVYVAGAPRFNHTGKVILFTMHNNRSLTIHQAMRGQQIGSYFGSEITSVDIDGDGVT 495
Query: 478 DILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNE 537
D+LLVGAPMY E E+GKVYVY L Q RF Y +L+ +S + +N
Sbjct: 496 DVLLVGAPMYFN-EGRERGKVYVYELRQNRFVYNGTLK------------DSHSYQN--- 539
Query: 538 PCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGG 597
ARFG++IA+V+DLN D +ND+V+GAPLED+H GA+YI+HG +I K QRI +
Sbjct: 540 ---ARFGSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASE 596
Query: 598 DGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQK 657
L++FG SIHG++DLN DGL D+ +G LG A + WSR V + +++FEP+K+NI
Sbjct: 597 LATGLQYFGCSIHGQLDLNEDGLIDLAVGALGNAVILWSRPVVQINASLHFEPSKINIFH 656
Query: 658 KNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKV 717
++C G++ C+ A +CF + ++Y T+D R R+ +R
Sbjct: 657 RDCKRSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMDERRYTPRAHLDEGGDRFT 716
Query: 718 QRNITVRKSE--CTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIP 775
R + + + C + +F++LD D+ V +++++L DP++GP+LDD P ++ +P
Sbjct: 717 NRAVLLSSGQELCERINFHVLDTADYVKPVTFSVEYSLEDPDHGPMLDDGWPTTLRVSVP 776
Query: 776 FAKDCGNKEKCISDL--------------------------SLHVATTEKDLLIVRSQND 809
F C E C+ DL S + + + + I+ S
Sbjct: 777 FWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYTLSFDTTVFIIESTRQ 836
Query: 810 KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESN----------HNITCK 859
+ V T++N ++AY+T + S NL F+ + IQK+ + + C
Sbjct: 837 RVAVEATLENRGENAYSTVLNISQSANLQFASL--IQKEDSDGSIECVNEERRLQKQVCN 894
Query: 860 VGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYE 919
V YPF R V F++ F+F+ S + ++ I L+A SDS E T DNV + +KYE
Sbjct: 895 VSYPFFRAKAKVAFRLDFEFSKSIFLHHLEIELAAGSDSNERDSTKEDNVAPLRFHLKYE 954
Query: 920 VGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFP 979
+ F S+S H + N + + + IG + + I+ G FP+ + + I+ P
Sbjct: 955 ADVLFTRSSSLSHYEVKLNSS----LERYDGIGPPFSCIFRIQNLGLFPIHGMMMKITIP 1010
Query: 980 NMTSNGYPVL-YPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCK 1038
T +G +L L+ N +C + + ++ + T + L+R L+ +
Sbjct: 1011 IATRSGNRLLKLRDFLTDEANTSC------NIWGNSTEYRPTPVEEDLRRAPQLNHSNSD 1064
Query: 1039 FATITCNLTSSDISQVNVSLI--LWKPTFIKSYFSSLNLTIRGEL-RSENASLVLSSSNQ 1095
+I CN+ ++N L+ LW + + S+ + + L R ++ + +
Sbjct: 1065 VVSINCNIRLVPNQEINFHLLGNLWLRSLKALKYKSMKIMVNAALQRQFHSPFIFREEDP 1124
Query: 1096 KRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKK 1148
R++ +ISK +VP+W+I WK+GFF+ +++
Sbjct: 1125 SRQIVFEISKQE-DWQVPIWIIVGSTLGGLLLLALLVLALWKLGFFRSARRRR 1176
>sp|P53710|ITA2_BOVIN PLATELET MEMBRANE GLYCOPROTEIN IA PRECURSOR (GPIA) (COLLAGEN
RECEPTOR) (INTEGRIN ALPHA-2) (VLA-2 ALPHA CHAIN) (CD49B)
pir||I45914 integrin alpha 2 subunit - bovine (fragment)
gb|AAB59255.1| (L25886) integrin alpha 2 subunit [Bos taurus]
Length = 1170
Score = 796 bits (2033), Expect = 0.0
Identities = 456/1174 (38%), Positives = 669/1174 (56%), Gaps = 65/1174 (5%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
+NV + + FSGP + FGY VQQ+ N +G W+L+GSP G PKNR GDVYKCPV
Sbjct: 19 YNVGLPKAKIFSGPSSEQFGYAVQQFINPKGNWLLVGSPWSGFPKNRMGDVYKCPVDLST 78
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPN-GGFLACGPLYAYRCGHLHYTTGI 119
+ C KL+L +TS+ NVTE+K NM+ G TL N GGFL CGPL+A +CG +YTTG+
Sbjct: 79 TT-CEKLNLQTSTSMSNVTEMKTNMSLGLTLTRNVGTGGFLTCGPLWAQQCGSQYYTTGV 137
Query: 120 CSDVSPTFQVVNSIAP-VQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQ 178
CSDVSP FQ+ S AP VQ C + +D+V+V D SNSIYPWD+V FL ++ +DIGP +
Sbjct: 138 CSDVSPDFQLRTSFAPAVQTCPSFIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTK 197
Query: 179 TQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEAR 238
TQ+G++QY N FNLN + S +E++ A + Q GG T T AR A++ A
Sbjct: 198 TQMGLIQYANNPRVVFNLNTFKSKDEMIKATSQTFQYGGDLTNTFKAIQYARDTAYSTAA 257
Query: 239 GARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEE 298
G R G KVMV+VTDGESHD +LK VI C +NI RF IA+LG NR L T+ ++E
Sbjct: 258 GGRPGATKVMVVVTDGESHDGSKLKAVIDQCNKDNILRFGIAVLGYLNRNALDTKNLIKE 317
Query: 299 IKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY 358
IK+IAS PTE+HFFNVSDE L+ T+GE+IF++E T Q +F+MEMSQ GFSA Y
Sbjct: 318 IKAIASIPTERHFFNVSDEADLLEKAGTIGEQIFSIEGTV-QGGDNFQMEMSQVGFSAEY 376
Query: 359 S--QDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSAT 416
S + +MLGAVGAYDW+GTVV + +I F E ++ +SYLGY+V ++
Sbjct: 377 SPQNNILMLGAVGAYDWSGTVVQKTPHGHLIFSKQAF--EQILQDRNHSSYLGYSV-ASI 433
Query: 417 ASSGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKDS 475
++ V ++AG PR N+TGQ+++Y + E+GN+ ++Q+ G+QIGSYFGS+L D++KD+
Sbjct: 434 STGNSVHFVAGAPRANYTGQIVLYSVNENGNVTVIQSQRGDQIGSYFGSVLCAVDVNKDT 493
Query: 476 NTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENK 535
TD+LLVGAPMYM K+E+G+VY++ + + + L E
Sbjct: 494 ITDVLLVGAPMYMNDLKKEEGRVYLFTITKGILNWHQFL------------------EGP 535
Query: 536 NEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPS 595
N ARFG+AIAA+ D+N+DGFND+++G+PLE+ + GAVYIY+G IR Y+Q+I
Sbjct: 536 NGLENARFGSAIAALSDINMDGFNDVIVGSPLENQNSGAVYIYNGHEGMIRLRYSQKI-L 594
Query: 596 GGD---GKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNK 652
G D L++FG+S+ G DLNGD +TDV++G G WS+ +A V V +F P K
Sbjct: 595 GSDRAFSSHLQYFGRSLDGYGDLNGDSITDVSVGAFGQVVQLWSQSIADVSVDASFTPKK 654
Query: 653 VNIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLD----SLRQISRSF 708
+ + KN ++ K +CF K + + + Y +T+D S R ISR
Sbjct: 655 ITLLNKNAEIKLK--------LCFSAKFRPTNQN-NQVAIVYNITIDEDQFSSRVISRGL 705
Query: 709 FSGTQERKVQRNITVRKSE-CTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLP 767
F ER +Q+ + V +++ C+++ ++ + D + + ++ +L +P P L+
Sbjct: 706 FKENNERCLQKTMIVSQAQRCSEYIIHIQEPSDIISPLNLCMNISLENPGTNPALEAYSE 765
Query: 768 NSVHEYIPFAKDCGNKEKCISDLSLHV---ATTEKDLLIVRSQNDKFNVSLTVKNTKDSA 824
IPF KDCG+ CISDL L+V T++ IV +QN + S+ +KN K+SA
Sbjct: 766 TVKVFSIPFHKDCGDDGVCISDLVLNVQQLPATQQQPFIVSNQNKRLTFSVQLKNKKESA 825
Query: 825 YNTRTIVHYSPNLVFS-------GIEAIQKDSCESNHNITCKVGYPFLRRGEMVTFKILF 877
YNT +V +S NL F+ G E + S ++TC VGYP L+ + VTF I F
Sbjct: 826 YNTEIVVDFSENLFFASWSMPVDGTE-VTCQIASSQKSVTCNVGYPALKSKQQVTFTINF 884
Query: 878 QFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAA 937
FN L +I A S+S+E E ++DN VN+ + + Y+ + S + ++
Sbjct: 885 DFNLQNLQNQASISFRALSESQE--ENMADNSVNLKLSLLYDAEIHITRSTNINFYEVSL 942
Query: 938 NETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSS 997
+ V V++S EDIG + IF + +GS P+ + I P T + P++Y TG+ +
Sbjct: 943 DGNVSSVVHSFEDIGPKF-IFSIKVTTGSVPVSMASVIIHIPQYTKDKNPLMYLTGVHTD 1001
Query: 998 ENANCRPHIFEDPFSI-NSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQ--- 1053
+ + +P I + ++ +++ + L+C T + I C L +
Sbjct: 1002 QAGDISCEAEINPLKIGQTSSSVSFKSENFRHIKELNCRTASCSNIMCWLRDLQVKGEYF 1061
Query: 1054 VNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVP 1113
+NVS +W TF S F ++ LT E+ + N + + N + + I K VP
Sbjct: 1062 LNVSTRIWNGTFAASTFQTVQLTAAAEIDTYNPQIYVIEENTV-TIPLTIMKPHEKVEVP 1120
Query: 1114 LWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKK 1147
VI WK+GFFKR +K
Sbjct: 1121 TGVIVGSVIAGILLLLALVAILWKLGFFKRKYEK 1154
>ref|NP_032422.1| integrin alpha 2 (Cd49b); VLA-2 receptor, alpha 2 subunit [Mus
musculus]
sp|Q62469|ITA2_MOUSE PLATELET MEMBRANE GLYCOPROTEIN IA PRECURSOR (GPIA) (COLLAGEN
RECEPTOR) (INTEGRIN ALPHA-2) (VLA-2 ALPHA CHAIN) (CD49B)
pir||S44142 VLA-2 protein homolog - mouse
emb|CAA82877.1| (Z29987) VLA-2 homologue [Mus musculus]
Length = 1178
Score = 793 bits (2027), Expect = 0.0
Identities = 459/1174 (39%), Positives = 673/1174 (57%), Gaps = 65/1174 (5%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
+NV + + FSGP + FGY+VQQ N +G W+L+GSP G P+NR GDVYKCPV
Sbjct: 27 YNVGLPGAKIFSGPSSEQFGYSVQQLTNPQGNWLLVGSPWSGFPENRMGDVYKCPVDL-P 85
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPN-GGFLACGPLYAYRCGHLHYTTGI 119
+ C KL+L + SI NVTE+K NM+ G TL NP GGFL CGPL+A++CG+ +Y TGI
Sbjct: 86 TATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNPGTGGFLTCGPLWAHQCGNQYYATGI 145
Query: 120 CSDVSPTFQVVNSIAP-VQECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQ 178
CSDVSP FQ + S +P VQ C + +D+V+V D SNSIYPW++V FL + +DIGPK+
Sbjct: 146 CSDVSPDFQFLTSFSPAVQACPSLVDVVVVCDESNSIYPWEAVKNFLVKFVTGLDIGPKK 205
Query: 179 TQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEAR 238
TQV ++QY FNLN + + E+++ A + Q GG T T + AR A+++
Sbjct: 206 TQVALIQYANEPRIIFNLNDFETKEDMVQATSETRQHGGDLTNTFRAIEFARDYAYSQTS 265
Query: 239 GARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEE 298
G R G KVMV+VTDGESHD +LK VIQ C D+ I RF IA+LG NR L T+ ++E
Sbjct: 266 GGRPGATKVMVVVTDGESHDGSKLKTVIQQCNDDEILRFGIAVLGYLNRNALDTKNLIKE 325
Query: 299 IKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY 358
IK+IAS PTE++FFNV+DE AL+ TLGE+IF++E T Q +F+MEM+Q GFSA Y
Sbjct: 326 IKAIASTPTERYFFNVADEAALLEKAGTLGEQIFSIEGTV-QGGDNFQMEMAQVGFSADY 384
Query: 359 S--QDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSAT 416
+ D +MLGAVGA+DW+GT+V + + + +I F+ +N +S+LGY+V + +
Sbjct: 385 APQNDILMLGAVGAFDWSGTLVQETSHKPVIFPKQAFDQVLQDRNH--SSFLGYSVAAIS 442
Query: 417 ASSGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKDS 475
G V ++AG PR N+TGQ+++Y + + GN+ ++Q+ G+QIGSYFGS+L + D+DKD+
Sbjct: 443 TEDG-VHFVAGAPRANYTGQIVLYSVNKQGNVTVIQSHRGDQIGSYFGSVLCSVDVDKDT 501
Query: 476 NTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENK 535
TD+LLVGAP YM K+E+GKVY++ + + LE + T
Sbjct: 502 ITDVLLVGAPTYMNDLKKEEGKVYLFTITKGILNQHQFLEGPEGT--------------- 546
Query: 536 NEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRI-- 593
ARFG+AIAA+ D+N+DGFND+++G+P+E+++ GAVYIY+G TIR +Y+Q+I
Sbjct: 547 ---GNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQKILG 603
Query: 594 PSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKV 653
+G + L+FFG+S+ G DLNGD +TDV+IG LG WS+ +A V + F P+K+
Sbjct: 604 SNGAFRRHLQFFGRSLDGYGDLNGDSITDVSIGALGQVIQLWSQSIADVAIEALFTPDKI 663
Query: 654 NIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLD----SLRQISRSFF 709
+ K+ I +CF + + A L + +TLD S R SR F
Sbjct: 664 TLLNKDAK--------ITLKLCFRAEFRPAGQNNQVAIL-FNMTLDADGHSSRVTSRGVF 714
Query: 710 SGTQERKVQRNITVRK-SECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPN 768
ER +Q+N+ V + +C++H + D + + + +D +L +P P L+
Sbjct: 715 RENSERFLQKNMVVNEVQKCSEHHISIQKPSDVVNPLDLRVDISLENPGTSPALEAYSET 774
Query: 769 SVHEYIPFAKDCGNKEKCISDLSLHV---ATTEKDLLIVRSQNDKFNVSLTVKNTKDSAY 825
IPF K+CG+ CISDL L V + IV +QN + S+ +KN +SAY
Sbjct: 775 VKVFSIPFYKECGSDGICISDLILDVQQLPAIQTQSFIVSNQNKRLTFSVILKNRGESAY 834
Query: 826 NTRTIVHYSPNLVFSGIEAI---QKDSCE---SNHNITCKVGYPFLRRGEMVTFKILFQF 879
NT + +S NL F+ + +CE S ++TC VGYP L+ + VTF I F F
Sbjct: 835 NTVVLAEFSENLFFASFSMPVDGTEVTCEVGSSQKSVTCDVGYPALKSEQQVTFTINFDF 894
Query: 880 NTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANE 939
N L I A S+S+E + +DN V+++IP+ Y+ L S + I+++E
Sbjct: 895 NLQNLQNQAAINFQAFSESQETNK--ADNSVSLTIPLLYDAELHLTRSTNINFYEISSDE 952
Query: 940 TVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSE- 998
P VI S EDIG + IF L +GS P+ ++I P T P+LY TG+ + +
Sbjct: 953 NAPSVIKSVEDIGPKF-IFSLKVTAGSAPVSMALVTIHIPQYTKEKNPLLYLTGIQTDQA 1011
Query: 999 -NANCRPHIFEDPFSI-NSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQ--- 1053
+ +C I +P + ++ ++ ++ + LDC T + ITC L +
Sbjct: 1012 GDISCTAEI--NPLKLPHTAPSVSFKNENFRHTKELDCRTTSCSNITCWLKDLHMKAEYF 1069
Query: 1054 VNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVP 1113
+NV+ +W TF S F ++ LT E+ + N L + N + + I K VP
Sbjct: 1070 INVTTRVWNRTFAASTFQTVQLTAAAEIDTHNPQLFVIEENAV-TIPLMIMKPTEKAEVP 1128
Query: 1114 LWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKK 1147
VI WK+GFFKR KK
Sbjct: 1129 TGVIIGSIIAGILLLLAMTAGLWKLGFFKRQYKK 1162
>gb|AAF21944.1|AF112345_1 (AF112345) integrin alpha 10 subunit [Homo sapiens]
Length = 1167
Score = 700 bits (1786), Expect = 0.0
Identities = 417/1179 (35%), Positives = 645/1179 (54%), Gaps = 66/1179 (5%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + F GP E FGY+V Q+ +W+L+G+P G +R GDVY+CPVG
Sbjct: 23 FNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVGGAH 82
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYTTGI 119
+ PC K L + + N + NM G +L+ T+ +GGF+AC PL++ CG +++GI
Sbjct: 83 NAPCAKGHLG-DYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFSSGI 141
Query: 120 CSDVSPTFQVVNSIAPV-QECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQ 178
C+ V +FQ S+AP Q C T +D+VIVLDGSNSIYPW V FL L+ ++ I P+Q
Sbjct: 142 CARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFIDPEQ 201
Query: 179 TQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEAR 238
QVG+VQYGE+ HE++L + + EEV+ AAK + +R GR+T TA A E F+++
Sbjct: 202 IQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSH 261
Query: 239 GARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEE 298
G R +++V+VTDGESHD L ++ CE + R+ IA+LG Y R F+ E
Sbjct: 262 GGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLRE 321
Query: 299 IKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY 358
I++IAS+P E+ FFNV+DE AL IV LG+RIF LE + ++ +SF +EMSQ GFS H
Sbjct: 322 IRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHR 381
Query: 359 SQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATAS 418
+D ++ G VGAYDW G+V+ + + P E + A+YLGY+V+S
Sbjct: 382 LKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSMLLR 441
Query: 419 SGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNT 477
G L+++G PR+ H G+VI +++ +DG +++ Q+L GEQIGSYFGS L D D+D T
Sbjct: 442 GGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRDGTT 501
Query: 478 DILLVGAPMYMGTEKEEQGKVYVYAL-NQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKN 536
D+LLV APM++G + +E G+VYVY + Q+ Q +L+P
Sbjct: 502 DVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQP-------------------E 542
Query: 537 EPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSG 596
P ARFG A+ A+ DLN DGF D+ +GAPLED H GA+Y+YHG+ +R AQRI +
Sbjct: 543 PPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAA 602
Query: 597 GDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQ 656
L +FG+S+ G +DL+GD L DV +G G A L SR + + ++ P +++
Sbjct: 603 SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVV 662
Query: 657 KKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERK 716
+++C G+E VC+ A +CF+V ++ ++ +++ +LD +R+ F G+ +R
Sbjct: 663 QRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRL 722
Query: 717 VQR--NITVRKSECTKHSFYMLDKHDFQDSVRITLDF---NLTDPENGPVLDDSLPNSVH 771
R ++V C + F++LD D+ V +T+ F N T P GPVL++ P S+
Sbjct: 723 SPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKP--GPVLNEGSPTSIQ 780
Query: 772 EYIPFAKDCGNKEKCISDLSLHV----ATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNT 827
+ +PF+KDCG +C++DL L V + K +VR K VS T++N K++AYNT
Sbjct: 781 KLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNT 840
Query: 828 RTIVHYSPNLVFSGI----EAIQKDSC--ESNHNITCKVGYPFLRRGEMVTFKILFQFNT 881
+ +S NL + + E+ K C S H C VG+P + G VTF + F+F+
Sbjct: 841 SLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSC 900
Query: 882 SYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETV 941
S L+ V + L+A+SDS E TL DN S ++YE L F S ++ + + T+
Sbjct: 901 SSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTL 960
Query: 942 PEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSS--SEN 999
P G E ++ G + + L +S P + G Y LS + N
Sbjct: 961 P------VGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGN---YFLSLSQVITNN 1011
Query: 1000 ANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTS-SDISQVNVSL 1058
A+C +P + L+ L+ + + + C+L + ++V+V L
Sbjct: 1012 ASCIVQNLTEP------PGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGL 1065
Query: 1059 --ILWKPTFIKSYFSSLNLTIRGELRSENAS-LVLSSSNQKRELAIQISKDGLPGRVPLW 1115
++ F ++ F SL + EL +E S L L+ +++ E +++ + P + LW
Sbjct: 1066 LRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQT-RPILISLW 1124
Query: 1116 VIXXXXXXXXXXXXXXXXXXWKIGFF---KRPLKKKMEK 1151
++ WK+GFF K P ++K E+
Sbjct: 1125 ILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREE 1163
>ref|NP_003628.1| integrin, alpha 10 [Homo sapiens]
gb|AAC31952.1| (AF074015) integrin subunit alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 696 bits (1777), Expect = 0.0
Identities = 416/1179 (35%), Positives = 644/1179 (54%), Gaps = 66/1179 (5%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + F GP E FGY+V Q+ +W+L+G+P G +R GDVY+CPVG
Sbjct: 23 FNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVGGAH 82
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYTTGI 119
+ PC K L + + N + NM G +L+ T+ +GGF+AC PL++ CG +++GI
Sbjct: 83 NAPCAKGHLG-DYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFSSGI 141
Query: 120 CSDVSPTFQVVNSIAPV-QECSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQ 178
C+ V +FQ S+AP Q C T +D+VIVLDGSNSIYPW V FL L+ ++ I P+Q
Sbjct: 142 CARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFIDPEQ 201
Query: 179 TQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEAR 238
QVG+VQYGE+ HE++L + + EEV+ AAK + +R GR+T TA A E F+++
Sbjct: 202 IQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSH 261
Query: 239 GARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEE 298
G R +++V+VTDGESHD L ++ CE + R+ IA+LG Y R F+ E
Sbjct: 262 GGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLRE 321
Query: 299 IKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY 358
I++IAS+P E+ FFNV+DE AL IV LG+RIF LE + ++ +SF +EMSQ GFS H
Sbjct: 322 IRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHR 381
Query: 359 SQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATAS 418
+D ++ G VGAYDW G+V+ + + P E + A+YLGY+V+S
Sbjct: 382 LKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSMLLR 441
Query: 419 SGDVLYIAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNT 477
G L+++G PR+ H G+VI +++ +DG +++ Q+L GEQIGSYFGS L D D+D T
Sbjct: 442 GGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRDGTT 501
Query: 478 DILLVGAPMYMGTEKEEQGKVYVYAL-NQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKN 536
D+LLV APM++G + +E G+VYVY + Q+ Q +L+P
Sbjct: 502 DVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQP-------------------E 542
Query: 537 EPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSG 596
P ARFG A+ A+ DLN DGF D+ +GAPLED H GA+Y+YHG+ +R AQRI +
Sbjct: 543 PPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAA 602
Query: 597 GDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQ 656
L +FG+S+ G +DL+GD L DV +G G A L SR + + ++ P +++
Sbjct: 603 SMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVV 662
Query: 657 KKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQERK 716
+++C G+E VC+ A +CF+V ++ ++ +++ +LD +R+ F G+ +R
Sbjct: 663 QRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRL 722
Query: 717 VQR--NITVRKSECTKHSFYMLDKHDFQDSVRITLDF---NLTDPENGPVLDDSLPNSVH 771
R ++V C + F++LD D+ V +T+ F N T P GPVL++ P S+
Sbjct: 723 SPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKP--GPVLNEGSPTSIQ 780
Query: 772 EYIPFAKDCGNKEKCISDLSLHV----ATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNT 827
+ +PF+KDCG +C++DL L V + K +VR K VS T++N K++AYNT
Sbjct: 781 KLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNT 840
Query: 828 RTIVHYSPNLVFSGI----EAIQKDSC--ESNHNITCKVGYPFLRRGEMVTFKILFQFNT 881
+ +S NL + + E+ K C S H C VG+P + G VTF + F+F+
Sbjct: 841 SLSIIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSC 900
Query: 882 SYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETV 941
S L+ V L+A+SDS E TL +N S ++YE L F S ++ + + T+
Sbjct: 901 SSLLSQVFGKLTASSDSLERNGTLQENTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTL 960
Query: 942 PEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSS--SEN 999
P G E ++ G + + L +S P + G Y LS + N
Sbjct: 961 P------VGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGN---YFLSLSQVITNN 1011
Query: 1000 ANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTS-SDISQVNVSL 1058
A+C +P + L+ L+ + + + C+L + ++V+V L
Sbjct: 1012 ASCIVQNLTEP------PGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGL 1065
Query: 1059 --ILWKPTFIKSYFSSLNLTIRGELRSENAS-LVLSSSNQKRELAIQISKDGLPGRVPLW 1115
++ F ++ F SL + EL +E S L L+ +++ E +++ + P + LW
Sbjct: 1066 LRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQT-RPILISLW 1124
Query: 1116 VIXXXXXXXXXXXXXXXXXXWKIGFF---KRPLKKKMEK 1151
++ WK+GFF K P ++K E+
Sbjct: 1125 ILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREE 1163
>sp|Q90615|ITA1_CHICK INTEGRIN ALPHA-1 (LAMININ AND COLLAGEN RECEPTOR) (VLA-1) (CD49A)
gb|AAA59067.1| (U10114) alpha 1 integrin [Gallus gallus]
Length = 285
Score = 483 bits (1231), Expect = e-135
Identities = 237/285 (83%), Positives = 260/285 (91%), Gaps = 1/285 (0%)
Query: 83 ENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAP-VQECST 141
ENMTFG+TLVTNP GGFLACGPLYAY+CG LHYTTG+CS+VS TF+ V ++AP VQEC T
Sbjct: 1 ENMTFGTTLVTNPKGGFLACGPLYAYKCGRLHYTTGVCSNVSSTFETVKAVAPSVQECKT 60
Query: 142 QLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
QLDIVIVLDGSNSIYPW+SVTAFLN LL+ MDIGP+QTQVGIVQYG+ V HEF LN YS+
Sbjct: 61 QLDIVIVLDGSNSIYPWESVTAFLNSLLRNMDIGPQQTQVGIVQYGQTVVHEFYLNTYST 120
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHR 261
TEEV+ AA +I QRGG QTMTALG DTAR+EAFTEA GARRGV+KVMVIVTDGESHDN+R
Sbjct: 121 TEEVMDAALRIRQRGGTQTMTALGIDTAREEAFTEAHGARRGVQKVMVIVTDGESHDNYR 180
Query: 262 LKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALV 321
L++VI CEDENIQRF+IAILGSY+RGNLSTEKFVEEIKSIAS+PTEKHFFNVSDELALV
Sbjct: 181 LQEVIDKCEDENIQRFAIAILGSYSRGNLSTEKFVEEIKSIASKPTEKHFFNVSDELALV 240
Query: 322 TIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLG 366
TIV+ LGERIFALEAT DQ AASFEMEMSQ GFSAHYSQDWVMLG
Sbjct: 241 TIVEALGERIFALEATTDQQAASFEMEMSQAGFSAHYSQDWVMLG 285
>pir||A55348 integrin alpha-1 - chicken (fragment)
Length = 272
Score = 455 bits (1157), Expect = e-126
Identities = 224/272 (82%), Positives = 247/272 (90%), Gaps = 1/272 (0%)
Query: 89 STLVTNPNGGFLACGPLYAYRCGHLHYTTGICSDVSPTFQVVNSIAP-VQECSTQLDIVI 147
+TLVTNP GGFLACGPLYAY+CG LHYTTG+CS+VS TF+ V ++AP VQEC TQLDIVI
Sbjct: 1 TTLVTNPKGGFLACGPLYAYKCGRLHYTTGVCSNVSSTFETVKAVAPSVQECKTQLDIVI 60
Query: 148 VLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLV 207
VLDGSNSIYPW+SVTAFLN LL+ MDIGP+QTQVGIVQYG+ V HEF LN YS+TEEV+
Sbjct: 61 VLDGSNSIYPWESVTAFLNSLLRNMDIGPQQTQVGIVQYGQTVVHEFYLNTYSTTEEVMD 120
Query: 208 AAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQ 267
AA +I QRGG QTMTALG DTAR+EAFTEA GARRGV+KVMVIVTDGESHDN+RL++VI
Sbjct: 121 AALRIRQRGGTQTMTALGIDTAREEAFTEAHGARRGVQKVMVIVTDGESHDNYRLQEVID 180
Query: 268 DCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTL 327
CEDENIQRF+IAILGSY+RGNLSTEKFVEEIKSIAS+PTEKHFFNVSDELALVTIV+ L
Sbjct: 181 KCEDENIQRFAIAILGSYSRGNLSTEKFVEEIKSIASKPTEKHFFNVSDELALVTIVEAL 240
Query: 328 GERIFALEATADQSAASFEMEMSQTGFSAHYS 359
GERIFALEAT DQ AASFEMEMSQ GFSAHYS
Sbjct: 241 GERIFALEATTDQQAASFEMEMSQAGFSAHYS 272
>gb|AAF61638.1|AF172723_1 (AF172723) integrin alpha 10 subunit [Homo sapiens]
Length = 517
Score = 451 bits (1148), Expect = e-125
Identities = 227/536 (42%), Positives = 329/536 (61%), Gaps = 21/536 (3%)
Query: 139 CSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNK 198
C T +D+VIVLDGSNSIYPW V FL L+ ++ I P+Q QVG+VQYGE+ HE++L
Sbjct: 1 CPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGD 60
Query: 199 YSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHD 258
+ + EEV+ AAK + +R GR+T TA A E F+++ G R +++V+VTDGESHD
Sbjct: 61 FRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHD 120
Query: 259 NHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEL 318
L ++ CE + R+ IA+LG Y R F+ EI++IAS+P E+ FFNV+DE
Sbjct: 121 GEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEA 180
Query: 319 ALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVV 378
AL IV LG+RIF LE + ++ +SF +EMSQ GFS H +D ++ G VGAYDW G+V+
Sbjct: 181 ALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVL 240
Query: 379 MQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVI 438
+ + P E + A+YLGY+V+S G L+++G PR+ H G+VI
Sbjct: 241 WLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVI 300
Query: 439 IYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGK 497
+++ +DG +++ Q+L GEQIGSYFGS L D D+D TD+LLV APM++G + +E G+
Sbjct: 301 AFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGR 360
Query: 498 VYVYAL-NQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLD 556
VYVY + Q+ Q +L+P P ARFG A+ A+ DLN D
Sbjct: 361 VYVYLVGQQSLLTLQGTLQP-------------------EPPQDARFGFAMGALPDLNQD 401
Query: 557 GFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLN 616
GF D+ +GAPLED H GA+Y+YHG+ +R AQRI + L +FG+S+ G +DL+
Sbjct: 402 GFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLD 461
Query: 617 GDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCINA 672
GD L DV +G G A L SR + + ++ P +++ +++C G+E VC+ A
Sbjct: 462 GDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTA 517
>gb|AAA69770.1| (L43058) integrin alpha 2 subunit [Xenopus laevis]
Length = 780
Score = 432 bits (1099), Expect = e-119
Identities = 261/800 (32%), Positives = 423/800 (52%), Gaps = 55/800 (6%)
Query: 368 VGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDVLYIAG 427
VGAYDW+GTVV +K+ Q I F +N+ +SYLGY+V + V ++AG
Sbjct: 1 VGAYDWSGTVVHEKSKQFSIFPYKAFEKVLHDRNQ--SSYLGYSV-AVINMKNSVHFVAG 57
Query: 428 QPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPM 486
PR ++TGQV++Y + GN+ ++QT GEQIGSYFGS+L + D+++DS TD+LLVGAP
Sbjct: 58 APRTDYTGQVVVYNITSQGNVSVIQTQRGEQIGSYFGSVLCSVDVNRDSITDVLLVGAPT 117
Query: 487 YMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTA 546
+M K+E+G+VY++++ + LE K + EN RFG+A
Sbjct: 118 FMNEYKKEEGQVYMFSIRDGILVQREQLEGPK------------SLEN------TRFGSA 159
Query: 547 IAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFG 606
I + D++LDG+ND+++GAPLE+ + GA+YI++G+ TIR +Y+Q+I L++FG
Sbjct: 160 IVELSDIDLDGYNDVIVGAPLENQNSGAIYIFNGNKNTIRTKYSQKILGSSFNPGLQYFG 219
Query: 607 QSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKE 666
+S+ G DLNGD + DV++G G WS+ VA V V F P ++ + KN
Sbjct: 220 RSVDGHQDLNGDTINDVSVGAYGKVIQLWSQHVADVSVKALFIPQQIVLTNKNAE----- 274
Query: 667 TVCINATVCFEVKLKSKEDTIYEADLQYRVTLD----SLRQISRSFFSGTQERKVQRNIT 722
+ +CF + A + Y TLD S R SR F + +R +QRNI
Sbjct: 275 ---VTVRICFSAVFRPANSQNSVA-VTYNATLDADLLSSRVTSRGQFRESNDRFLQRNIV 330
Query: 723 VRKSE-CTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPFAKDCG 781
+ +E C +H F + + D ++++ + ++ +P + PVL+ +S +IPF KDCG
Sbjct: 331 IGPTESCFEHVFNVQETSDSENALALRINVVAQNPGSSPVLNPYSSSSTEWFIPFLKDCG 390
Query: 782 NKEKCISDLSLHVATTEKDL---LIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLV 838
+ + CISDLSL + D+ IV ++ + +T+ N ++AYNTR +S NL
Sbjct: 391 DDKICISDLSLQIQQIPSDIKSPYIVSMKDRRLLFQVTLTNKLENAYNTRLNAIFSENLF 450
Query: 839 FSGIEAIQKDSCE-------SNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIY 891
F+ I +D E + ++++C +G+PFL+ + V F I F FN + L IY
Sbjct: 451 FAS-STIPRDGTEVLCQVGNTQNSVSCLIGFPFLKDSQKVIFDIWFDFNLNNLQNTAFIY 509
Query: 892 LSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDI 951
ATS+S E E DN VNI++PV+Y+ + + + +P V+N+ +DI
Sbjct: 510 FQATSESREARE--EDNSVNITLPVQYDAEIHLTRVTNINFYEVFPGLNIPSVVNTFDDI 567
Query: 952 GNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPF 1011
G E N F + +G+ P+ LSI+ P T + P+LY T + + + + +P
Sbjct: 568 GLEFN-FTVKVSTGTVPLKTAYLSINVPQFTKSNNPLLYITSVQTDQMTGVSSNRVINPA 626
Query: 1012 SINS-GKKMTTSTDHLKRGTILDCNTCKFATITC---NLTSSDISQVNVSLILWKPTFIK 1067
+ K + ++LK +L+C + + I C NL + VNVS +W TF
Sbjct: 627 HVEKIPYKPSFKEENLKAVHVLNCESARCVAIKCFLENLQLREDYYVNVSTRIWNGTFAA 686
Query: 1068 SYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXX 1127
++F ++ L +L + ++ + + SN+ + + I+K G VP+ V+
Sbjct: 687 AHFQTIELVANAKLETIDSEIFV-VSNKDVMIPLTITKPGEKSEVPIGVVIGSAIAGLVL 745
Query: 1128 XXXXXXXXWKIGFFKRPLKK 1147
WK+GFFKR +K
Sbjct: 746 LAALVALLWKLGFFKRKYQK 765
>emb|CAA53178.1| (X75427) alpha 2 integrin [Mus musculus]
Length = 729
Score = 399 bits (1014), Expect = e-109
Identities = 252/746 (33%), Positives = 389/746 (51%), Gaps = 56/746 (7%)
Query: 425 IAGQPRYNHTGQVIIYRM-EDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVG 483
+AG PR N+TGQ+++Y + + GN+ ++Q+ G+QIGSYFGS+L + D+DKD+ TD+LLVG
Sbjct: 1 VAGAPRANYTGQIVLYSVNKQGNVTVIQSHRGDQIGSYFGSVLCSVDVDKDTITDVLLVG 60
Query: 484 APMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARF 543
AP YM K+E+GKVY++ + + LE + T ARF
Sbjct: 61 APTYMNDLKKEEGKVYLFTITKGILNQHQFLEGPEGT------------------GNARF 102
Query: 544 GTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEYAQRI--PSGGDGKT 601
G+AIAA+ D+N+DGFND+++G+P+E+++ GAVYIY+G TIR +Y+Q+I +G +
Sbjct: 103 GSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQKILGSNGAFRRH 162
Query: 602 LKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCH 661
L+FFG+S+ G DLNGD +TDV+IG LG WS+ +A V + F P+K+ + K+
Sbjct: 163 LQFFGRSLDGYGDLNGDSITDVSIGALGQVIQLWSQSIADVAIEALFTPDKITLLNKDAK 222
Query: 662 MEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLD----SLRQISRSFFSGTQERKV 717
I +CF + + A L + +TLD S R SR F ER +
Sbjct: 223 --------ITLKLCFRAEFRPAGQNNQVAIL-FNMTLDADGHSSRVTSRGVFRENSERFL 273
Query: 718 QRNITVRK-SECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGPVLDDSLPNSVHEYIPF 776
Q+N+ V + +C++H + D + + + +D +L +P P L+ IPF
Sbjct: 274 QKNMVVNEVQKCSEHHISIQKPSDVVNPLDLRVDISLENPGTSPALEAYSETVKVFSIPF 333
Query: 777 AKDCGNKEKCISDLSLHV---ATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHY 833
K+CG+ CISDL L V + IV +QN + S+ +KN +SAYNT + +
Sbjct: 334 YKECGSDGICISDLILDVQQLPAIQTQSFIVSNQNKRLTFSVILKNRGESAYNTVVLAEF 393
Query: 834 SPNLVFSGIEAI---QKDSCE---SNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMEN 887
S NL F+ + +CE S ++TC VGYP L+ + VTF I F FN L
Sbjct: 394 SENLFFASFSMPVDGTEVTCEVGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQNQ 453
Query: 888 VTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYSSASEYHISIAANETVPEVINS 947
I A S+S+E + +DN V+++IP+ Y+ L S + I+++E P VI S
Sbjct: 454 AAINFQAFSESQETNK--ADNSVSLTIPLLYDAELHLTRSTNINFYEISSDENAPSVIKS 511
Query: 948 TEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMTSNGYPVLYPTGLSSSE--NANCRPH 1005
EDIG + IF L +GS P+ ++I P T P+LY TG+ + + + +C
Sbjct: 512 VEDIGPKF-IFSLKVTAGSAPVSMALVTIHIPQYTKEKNPLLYLTGIQTDQAGDISCTAE 570
Query: 1006 IFEDPFSI-NSGKKMTTSTDHLKRGTILDCNTCKFATITCNLTSSDISQ---VNVSLILW 1061
I +P + ++ ++ ++ + LDC T + ITC L + +NV+ +W
Sbjct: 571 I--NPLKLPHTAPSVSFKNENFRHTKELDCRTTSCSNITCWLKDLHMKAEYFINVTTRVW 628
Query: 1062 KPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXX 1121
TF S F ++ LT E+ + N L + N + + I K VP VI
Sbjct: 629 NRTFAASTFQTVQLTAAAEIDTHNPQLFVIEENAV-TIPLMIMKPTEKAEVPTGVIIGSI 687
Query: 1122 XXXXXXXXXXXXXXWKIGFFKRPLKK 1147
WK+GFFKR KK
Sbjct: 688 IAGILLLLAMTAGLWKLGFFKRQYKK 713
>pdb|1QC5|A Chain A, I Domain From Integrin Alpha1-Beta1
Length = 192
Score = 378 bits (960), Expect = e-103
Identities = 190/192 (98%), Positives = 192/192 (99%)
Query: 140 STQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKY 199
STQLDIVIVLDGSNSIYPWDSVTAFLNDLL+RMDIGPKQTQVGIVQYGENVTHEFNLNKY
Sbjct: 1 STQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKY 60
Query: 200 SSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHDN 259
SSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHDN
Sbjct: 61 SSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHDN 120
Query: 260 HRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELA 319
HRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDE+A
Sbjct: 121 HRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEIA 180
Query: 320 LVTIVKTLGERI 331
LVTIVKTLGERI
Sbjct: 181 LVTIVKTLGERI 192
>pdb|1QC5|B Chain B, I Domain From Integrin Alpha1-Beta1
Length = 192
Score = 376 bits (954), Expect = e-102
Identities = 189/192 (98%), Positives = 191/192 (99%)
Query: 140 STQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKY 199
STQLDIVIVLDGSNSIYPWDSVTAFLNDLL+RMDIGPKQTQVGIVQYGENVTHEFNLNKY
Sbjct: 1 STQLDIVIVLDGSNSIYPWDSVTAFLNDLLERMDIGPKQTQVGIVQYGENVTHEFNLNKY 60
Query: 200 SSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHDN 259
SSTEEVLVAAKKIVQRGGRQTMTALG DTARKEAFTEARGARRGVKKVMVIVTDGESHDN
Sbjct: 61 SSTEEVLVAAKKIVQRGGRQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHDN 120
Query: 260 HRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELA 319
HRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDE+A
Sbjct: 121 HRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEIA 180
Query: 320 LVTIVKTLGERI 331
LVTIVKTLGERI
Sbjct: 181 LVTIVKTLGERI 192
>ref|NP_000623.1| integrin alpha M; antigen CD11b (p170); macrophage antigen alpha
polypeptide; neutrophil adherence receptor alpha-M
subunit; Integrin, alpha-M (complement component
receptor-3, alpha; antigen CD11B (p170); macrophage
antigen, alpha polypeptide); compl>
gb|AAA59491.1| (M18044) leukocyte adhesion glycoprotein precursor [Homo sapiens]
Length = 1152
Score = 376 bits (954), Expect = e-102
Identities = 333/1202 (27%), Positives = 540/1202 (44%), Gaps = 126/1202 (10%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D +N+MTF FG +V Q + G V++G+P N+ G +Y+C G
Sbjct: 17 FNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRGSLYQCDYSTGS 72
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYTTGI 119
P ++L +PV NM+ G +L T LACGP C Y G+
Sbjct: 73 CEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGL 122
Query: 120 CSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTAFLNDLLKRMDI 174
C + P ++ C + DI ++DGS SI P D + F++ +++++
Sbjct: 123 CFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK- 181
Query: 175 GPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAF 234
+T ++QY E F ++ + K I Q GR T TA G +E F
Sbjct: 182 -KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKVVRELF 239
Query: 235 TEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTE 293
GAR+ K++V++TDGE D + VI + + E + R+ I + ++ +E
Sbjct: 240 NITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFR-----SE 294
Query: 294 KFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTG 353
K +E+ +IAS+P H F V++ AL TI L E+IFA+E T S++SFE EMSQ G
Sbjct: 295 KSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEG 354
Query: 354 FSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVN 413
FSA + + +L VG+YDW G V + + + +TF + ++ +YLGY
Sbjct: 355 FSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSDMNDAYLGYAAA 409
Query: 414 SATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDK 473
+ L + G PRY H G V ++R G + + G QIG+YFG+ L + D+D
Sbjct: 410 IILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDS 468
Query: 474 DSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 533
+ +TD++L+GAP Y E+ G+V V L + R +Q C + +
Sbjct: 469 NGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQ----------CDAVLYG----- 511
Query: 534 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYAQR 592
+ +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG SG I ++QR
Sbjct: 512 EQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQR 570
Query: 593 IPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNK 652
I L++FGQS+ G DL DGL D+T+G G L S+ V VK M F P +
Sbjct: 571 IAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPRE 630
Query: 653 VNIQKKNCH---MEGKETVCINATVCFEVKLKSKEDTIYEADLQ----YRVTLDSLRQIS 705
V C+ ++GKE VC V+ KS D + E +Q Y + LDS R S
Sbjct: 631 VARNVFECNDQVVKGKEAG--EVRVCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRPHS 687
Query: 706 RSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNLTDPENG--- 759
R+ F+ T + +R V T + + + +D V + L+F+L
Sbjct: 688 RAVFNET-KNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFG 746
Query: 760 ---PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLT 816
PVL + PF K+CGN C DLS+ + D L+V + FNV++T
Sbjct: 747 NLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE-FNVTVT 805
Query: 817 VKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESN---------HNITCK 859
V+N + +Y T+ + +L + + +Q +CES + +C
Sbjct: 806 VRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCS 865
Query: 860 VGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYE 919
+ +P VTF I F ++ + N + L A SE + + +PVKY
Sbjct: 866 INHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKTEFQLELPVKYA 924
Query: 920 VGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF 978
V + S S +++ A+E V+ + N L ++S P + L
Sbjct: 925 VYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN------LGQRS-----PPISLVFLV 973
Query: 979 PNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRGTILDCN 1035
P + N + ++ SEN + H E ++ + +D L++ +++C+
Sbjct: 974 P-VRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFLAELRKAPVVNCS 1023
Query: 1036 TCKFATITCNLTSSDI-SQVNVSL--ILWKPTFIKSYFSSLNLTIRGELRSENASLVL-- 1090
I C++ I + N +L L +IK+ + L + E+ ++ L
Sbjct: 1024 IAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLLP 1083
Query: 1091 -SSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKM 1149
+ + + ++ +P +PL I +K+GFFKR K M
Sbjct: 1084 GQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYKLGFFKRQYKDMM 1141
Query: 1150 EK 1151
+
Sbjct: 1142 SE 1143
>sp|P11215|ITAM_HUMAN CELL SURFACE GLYCOPROTEIN MAC-1 ALPHA SUBUNIT PRECURSOR (CR-3 ALPHA
CHAIN) (CD11B) (LEUKOCYTE ADHESION RECEPTOR MO1)
(INTEGRIN ALPHA-M) (NEUTROPHIL ADHERENCE RECEPTOR)
gb|AAB24821.1| (S52228) leukocyte integrin alpha chain [human, Peptide, 1152 aa]
[Homo sapiens]
Length = 1152
Score = 375 bits (952), Expect = e-102
Identities = 329/1203 (27%), Positives = 537/1203 (44%), Gaps = 128/1203 (10%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D +N+MTF FG +V Q + G V++G+P N+ G +Y+C G
Sbjct: 17 FNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRGSLYQCDYSTGS 72
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYTTGI 119
P ++L +PV NM+ G +L T LACGP C Y G+
Sbjct: 73 CEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGL 122
Query: 120 CSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTAFLNDLLKRMDI 174
C + P ++ C + DI ++DGS SI P D + F++ +++++
Sbjct: 123 CFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK- 181
Query: 175 GPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAF 234
+T ++QY E F ++ + K I Q GR T TA G +E F
Sbjct: 182 -KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKVVRELF 239
Query: 235 TEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTE 293
GAR+ K++V++TDGE D + VI + + E + R+ I + ++ +E
Sbjct: 240 NITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFR-----SE 294
Query: 294 KFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTG 353
K +E+ +IAS+P H F V++ AL TI L E+IFA+E T S++SFE EMSQ G
Sbjct: 295 KSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEG 354
Query: 354 FSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVN 413
FSA + + +L VG+YDW G V + + + +TF + ++ +YLGY
Sbjct: 355 FSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSDMNDAYLGYAAA 409
Query: 414 SATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDK 473
+ L + G PRY H G V ++R G + + G QIG+YFG+ L + D+D
Sbjct: 410 IILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDS 468
Query: 474 DSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 533
+ +TD++L+GAP Y E+ G+V V L + R +Q C + +
Sbjct: 469 NGSTDLVLIGAPHYY--EQTRGGQVSVCPLPRGRARWQ----------CDAVLYGE---- 512
Query: 534 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYAQR 592
+ +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG SG I ++QR
Sbjct: 513 -QGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQR 570
Query: 593 IPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNK 652
I L++FGQS+ G DL DGL D+T+G G L S+ V VK M F P +
Sbjct: 571 IAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPRE 630
Query: 653 VNIQKKNCH---MEGKETVCINATVCFEVKLKSKEDTIYEADLQ----YRVTLDSLRQIS 705
V C+ ++GKE + VC V+ KS D + E +Q Y + LDS R S
Sbjct: 631 VARNVFECNDQVVKGKEAGEVR--VCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRPHS 687
Query: 706 RSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNLTDPENG--- 759
R+ F+ T+ +R V T + + + +D V + L+F+L
Sbjct: 688 RAVFNETKN-STRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFG 746
Query: 760 ---PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLT 816
PVL + PF K+CGN C DLS+ + D L+V + FNV++T
Sbjct: 747 NLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE-FNVTVT 805
Query: 817 VKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESNHNI---------TCK 859
V+N + +Y T+ + +L + + +Q +CES + +C
Sbjct: 806 VRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCS 865
Query: 860 VGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYE 919
+ +P VTF I F ++ + N + L A SE + + +PVKY
Sbjct: 866 INHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKTEFQLELPVKYA 924
Query: 920 VGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF 978
V + S S +++ A+E V+ + N L +S+ F
Sbjct: 925 VYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------LGQRSLPISLVF 971
Query: 979 PNMTSNGYPVLYPTG-LSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRGTILDC 1034
V++ ++ SEN + H E ++ + +D L++ +++C
Sbjct: 972 LVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFLAELRKAPVVNC 1022
Query: 1035 NTCKFATITCNLTSSDISQVNVSLILWKPTF---IKSYFSSLNLTIRGELRSENASLVL- 1090
+ I C++ I + + + +F IK+ + L + E+ ++ L
Sbjct: 1023 SIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLL 1082
Query: 1091 --SSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKK 1148
+ + + ++ +P +PL I +K+GFFKR K
Sbjct: 1083 PGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1140
Query: 1149 MEK 1151
M +
Sbjct: 1141 MSE 1143
>gb|AAA59903.1| (J04145) neutrophil adherence receptor alpha-M subunit [Homo sapiens]
Length = 1145
Score = 372 bits (946), Expect = e-102
Identities = 328/1203 (27%), Positives = 537/1203 (44%), Gaps = 127/1203 (10%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D +N+MTF FG +V Q + G V++G+P N+ G +Y+C G
Sbjct: 9 FNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRGSLYQCDYSTGS 64
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYTTGI 119
P ++L +PV NM+ G +L T LACGP C Y G+
Sbjct: 65 CEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGL 114
Query: 120 CSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTAFLNDLLKRMDI 174
C + P ++ C + DI ++DGS SI P D + F++ +++++
Sbjct: 115 CFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK- 173
Query: 175 GPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAF 234
+T ++QY E F ++ + K I Q GR T TA G +E F
Sbjct: 174 -KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKVVRELF 231
Query: 235 TEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTE 293
GAR+ K++V++TDGE D + VI + + E + R+ I + ++ +E
Sbjct: 232 NITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFR-----SE 286
Query: 294 KFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTG 353
K +E+ +IAS+P H F V++ AL TI L E+IFA+E T S++SFE EMSQ G
Sbjct: 287 KSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEG 346
Query: 354 FSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVN 413
FSA + + +L VG+YDW G V + + + +TF + ++ +YLGY
Sbjct: 347 FSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSDMNDAYLGYAAA 401
Query: 414 SATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDK 473
+ L + G PRY H G V ++R G + + G QIG+YFG+ L + D+D
Sbjct: 402 IILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDS 460
Query: 474 DSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 533
+ +TD++L+GAP Y QTR Q+S+ P+ + + Q ++
Sbjct: 461 NGSTDLVLIGAPHYY---------------EQTRGG-QVSVCPLPRGQRARWQCDAVLYG 504
Query: 534 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYAQR 592
+ +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG SG I ++QR
Sbjct: 505 EQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQR 563
Query: 593 IPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNK 652
I L++FGQS+ G DL DGL D+T+G G L S+ V VK M F P +
Sbjct: 564 IAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPRE 623
Query: 653 VNIQKKNCH---MEGKETVCINATVCFEVKLKSKEDTIYEADLQ----YRVTLDSLRQIS 705
V C+ ++GKE + VC V+ KS D + E +Q Y + LDS R S
Sbjct: 624 VARNVFECNDQVVKGKEAGEVR--VCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRPHS 680
Query: 706 RSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNLTDPENG--- 759
R+ F+ T+ +R V T + + + +D V + L+F+L
Sbjct: 681 RAVFNETKN-STRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFG 739
Query: 760 ---PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLT 816
PVL + PF K+CGN C DLS+ + D L+V + FNV++T
Sbjct: 740 NLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE-FNVTVT 798
Query: 817 VKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESNHNI---------TCK 859
V+N + +Y T+ + +L + + +Q +CES + +C
Sbjct: 799 VRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCS 858
Query: 860 VGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYE 919
+ +P VTF I F ++ + N + L A SE + + +PVKY
Sbjct: 859 INHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKTEFQLELPVKYA 917
Query: 920 VGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF 978
V + S S +++ A+E V+ + N L +S+ F
Sbjct: 918 VYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------LGQRSLPISLVF 964
Query: 979 PNMTSNGYPVLYPTG-LSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRGTILDC 1034
V++ ++ SEN + H E ++ + +D L++ +++C
Sbjct: 965 LVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFLAELRKAPVVNC 1015
Query: 1035 NTCKFATITCNLTSSDISQVNVSLILWKPTF---IKSYFSSLNLTIRGELRSENASLVL- 1090
+ I C++ I + + + +F IK+ + L + E+ ++ L
Sbjct: 1016 SIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLL 1075
Query: 1091 --SSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKK 1148
+ + + ++ +P +PL I +K+GFFKR K
Sbjct: 1076 PGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1133
Query: 1149 MEK 1151
M +
Sbjct: 1134 MSE 1136
>pir||RWHU1B cell surface glycoprotein CD11b precursor - human
gb|AAA59544.1| (J03925) glycoprotein Mac-1 [Homo sapiens]
Length = 1153
Score = 372 bits (946), Expect = e-102
Identities = 328/1203 (27%), Positives = 537/1203 (44%), Gaps = 127/1203 (10%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D +N+MTF FG +V Q + G V++G+P N+ G +Y+C G
Sbjct: 17 FNLDTENAMTFQENARG-FGQSVVQLQ---GSRVVVGAPQEIVAANQRGSLYQCDYSTGS 72
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLV-TNPNGGFLACGPLYAYRCGHLHYTTGI 119
P ++L +PV NM+ G +L T LACGP C Y G+
Sbjct: 73 CEP-IRLQVPVEAV---------NMSLGLSLAATTSPPQLLACGPTVHQTCSENTYVKGL 122
Query: 120 CSDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTAFLNDLLKRMDI 174
C + P ++ C + DI ++DGS SI P D + F++ +++++
Sbjct: 123 CFLFGSNLRQQPQKFPEALRGCPQEDSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLK- 181
Query: 175 GPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAF 234
+T ++QY E F ++ + K I Q GR T TA G +E F
Sbjct: 182 -KSKTLFSLMQYSEEFRIHFTFKEFQNNPNPRSLVKPITQLLGR-THTATGIRKVVRELF 239
Query: 235 TEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTE 293
GAR+ K++V++TDGE D + VI + + E + R+ I + ++ +E
Sbjct: 240 NITNGARKNAFKILVVITDGEKFGDPLGYEDVIPEADREGVIRYVIGVGDAFR-----SE 294
Query: 294 KFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTG 353
K +E+ +IAS+P H F V++ AL TI L E+IFA+E T S++SFE EMSQ G
Sbjct: 295 KSRQELNTIASKPPRDHVFQVNNFEALKTIQNQLREKIFAIEGTQTGSSSSFEHEMSQEG 354
Query: 354 FSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVN 413
FSA + + +L VG+YDW G V + + + +TF + ++ +YLGY
Sbjct: 355 FSAAITSNGPLLSTVGSYDWAGGVFLYTSKE-----KSTFINMTRVDSDMNDAYLGYAAA 409
Query: 414 SATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDK 473
+ L + G PRY H G V ++R G + + G QIG+YFG+ L + D+D
Sbjct: 410 IILRNRVQSL-VLGAPRYQHIGLVAMFRQNTGMWESNANVKGTQIGAYFGASLCSVDVDS 468
Query: 474 DSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 533
+ +TD++L+GAP Y QTR Q+S+ P+ + + Q ++
Sbjct: 469 NGSTDLVLIGAPHYY---------------EQTRGG-QVSVCPLPRGQRARWQCDAVLYG 512
Query: 534 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYAQR 592
+ +P G RFG A+ + D+N D D+ IGAP E+D+ GAVY++HG SG I ++QR
Sbjct: 513 EQGQPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQR 571
Query: 593 IPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNK 652
I L++FGQS+ G DL DGL D+T+G G L S+ V VK M F P +
Sbjct: 572 IAGSKLSPRLQYFGQSLSGGQDLTMDGLVDLTVGAQGHVLLLRSQPVLRVKAIMEFNPRE 631
Query: 653 VNIQKKNCH---MEGKETVCINATVCFEVKLKSKEDTIYEADLQ----YRVTLDSLRQIS 705
V C+ ++GKE + VC V+ KS D + E +Q Y + LDS R S
Sbjct: 632 VARNVFECNDQVVKGKEAGEVR--VCLHVQ-KSTRDRLREGQIQSVVTYDLALDSGRPHS 688
Query: 706 RSFFSGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVR---ITLDFNLTDPENG--- 759
R+ F+ T+ +R V T + + + +D V + L+F+L
Sbjct: 689 RAVFNETKN-STRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSLVGTPLSAFG 747
Query: 760 ---PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLT 816
PVL + PF K+CGN C DLS+ + D L+V + FNV++T
Sbjct: 748 NLRPVLAEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFMSLDCLVVGGPRE-FNVTVT 806
Query: 817 VKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCESNHNI---------TCK 859
V+N + +Y T+ + +L + + +Q +CES + +C
Sbjct: 807 VRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSGALKSTSCS 866
Query: 860 VGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYE 919
+ +P VTF I F ++ + N + L A SE + + +PVKY
Sbjct: 867 INHPIFPENSEVTFNITFDVDSKASLGN-KLLLKANVTSENNMPRTNKTEFQLELPVKYA 925
Query: 920 VGLQFYS-SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF 978
V + S S +++ A+E V+ + N L +S+ F
Sbjct: 926 VYMVVTSHGVSTKYLNFTASENTSRVMQHQYQVSN-------------LGQRSLPISLVF 972
Query: 979 PNMTSNGYPVLYPTG-LSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRGTILDC 1034
V++ ++ SEN + H E ++ + +D L++ +++C
Sbjct: 973 LVPVRLNQTVIWDRPQVTFSENLSSTCHTKE---------RLPSHSDFLAELRKAPVVNC 1023
Query: 1035 NTCKFATITCNLTSSDISQVNVSLILWKPTF---IKSYFSSLNLTIRGELRSENASLVL- 1090
+ I C++ I + + + +F IK+ + L + E+ ++ L
Sbjct: 1024 SIAVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLIVSTAEILFNDSVFTLL 1083
Query: 1091 --SSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKK 1148
+ + + ++ +P +PL I +K+GFFKR K
Sbjct: 1084 PGQGAFVRSQTETKVEPFEVPNPLPL--IVGSSVGGLLLLALITAALYKLGFFKRQYKDM 1141
Query: 1149 MEK 1151
M +
Sbjct: 1142 MSE 1144
>pdb|1CK4|B Chain B, Crystal Structure Of Rat A1b1 Integrin I-Domain.
pdb|1CK4|A Chain A, Crystal Structure Of Rat A1b1 Integrin I-Domain
Length = 198
Score = 368 bits (935), Expect = e-100
Identities = 186/198 (93%), Positives = 191/198 (95%)
Query: 139 CSTQLDIVIVLDGSNSIYPWDSVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNK 198
CSTQLDIVIVLDGSNSIYPW+SV AFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNK
Sbjct: 1 CSTQLDIVIVLDGSNSIYPWESVIAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNK 60
Query: 199 YSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESHD 258
YSSTEEVLVAA KI ++GG QTMTALG DTARKEAFTEARGARRGVKKVMVIVTDGESHD
Sbjct: 61 YSSTEEVLVAANKIGRQGGLQTMTALGIDTARKEAFTEARGARRGVKKVMVIVTDGESHD 120
Query: 259 NHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEL 318
N+RLK+VIQDCEDENIQRFSIAILG YNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEL
Sbjct: 121 NYRLKQVIQDCEDENIQRFSIAILGHYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDEL 180
Query: 319 ALVTIVKTLGERIFALEA 336
ALVTIVK LGERIFALEA
Sbjct: 181 ALVTIVKALGERIFALEA 198
>sp|P20701|ITAL_HUMAN LEUKOCYTE ADHESION GLYCOPROTEIN LFA-1 ALPHA CHAIN PRECURSOR
(LEUKOCYTE FUNCTION ASSOCIATED MOLECULE 1, ALPHA CHAIN)
(CD11A) (INTEGRIN ALPHA-L)
Length = 1170
Score = 365 bits (928), Expect = 1e-99
Identities = 328/1200 (27%), Positives = 540/1200 (44%), Gaps = 149/1200 (12%)
Query: 1 FNVDVKNSMTFSGPVEDM-FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRG 59
+N+DV+ + +FS P FGY V Q G V++G+P G N TG +Y+C G G
Sbjct: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQCQSGTG 78
Query: 60 ESLPCVKLDLPVNTSIPNVTEVKENMT---FGSTLVTNP-NGGFLACGPLYAYRCGHLHY 115
LP VT N T G TL T+P +G LAC P + C Y
Sbjct: 79 HCLP--------------VTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTY 124
Query: 116 TTGICSDVSPTFQ--VVNSIAPVQEC-STQLDIVIVLDGSNSIYP--WDSVTAFLNDLLK 170
+G+C Q ++ QEC +D+V + DGS S+ P + + F+ D++K
Sbjct: 125 LSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMK 184
Query: 171 RMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTAR 230
++ Q VQ+ + EF+ + Y ++ A K V+ T T +
Sbjct: 185 KLS--NTSYQFAAVQFSTSYKTEFDFSDYVKRKDP-DALLKHVKHMLLLTNTFGAINYVA 241
Query: 231 KEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNL 290
E F E GAR KV++I+TDGE+ D+ + ++I R+ I I +
Sbjct: 242 TEVFREELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRYIIGI-----GKHF 290
Query: 291 STEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEM 349
T++ E + AS+P + F + D L + L ++I+ +E T+ Q SF ME+
Sbjct: 291 QTKESQETLHKFASKPASE-FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMEL 349
Query: 350 SQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLG 409
S +G SA S+ ++GAVGA DW G + KA ++ TF E A YLG
Sbjct: 350 SSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADL----QDDTFIGNEPLTPEVRAGYLG 405
Query: 410 YTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSILT 467
YTV + L +G PRY H G+V++++ G + +QT+ G QIGSYFG L
Sbjct: 406 YTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELC 465
Query: 468 TTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQH 527
D+D+D T++LL+GAP++ G ++ G+V++Y Q FE L+
Sbjct: 466 GVDVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG----------- 512
Query: 528 NSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRK 587
+ P G RFG AI A+ D+N DG D+ +GAPLE+ GAVYI++G +
Sbjct: 513 ------DPGYPLG-RFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSP 563
Query: 588 EYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMN 647
+ +QRI +++FG+SIHG DL GDGL DV +G + SR V + M+
Sbjct: 564 QPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMS 623
Query: 648 FEPNKVNIQKKNC--HMEGKETVCINATVCFEVK-LKSKEDTIYEADLQYRVTLDSLRQI 704
F P ++ + + C K +N T+CF++K L + A+L Y + LD R
Sbjct: 624 FSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLYPQFQGRLVANLTYTLQLDGHRTR 683
Query: 705 SRSFFSGTQERKVQRNITVRKS-ECTKHSFYM-LDKHDFQDSVRITLDFNLTDPEN---- 758
R F G + +++RNI V S CT SF+ + D + ++L+F+L + E
Sbjct: 684 RRGLFPGGR-HELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRD 742
Query: 759 --------GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDK 810
P+L SL + E IPF K+CG +KC ++L + + L + +
Sbjct: 743 QRAQGKDIPPILRPSLHSETWE-IPFEKNCGEDKKCEANLRVSFSPARSRALRL-TAFAS 800
Query: 811 FNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNIT 857
+V L++ N ++ AY + +H+ P L F +E ++ SCE + ++
Sbjct: 801 LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALS 860
Query: 858 CKVGYPFLRRGEMVTFKILFQ--FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIP 915
C V P + G V +++F N+S+ ++V ++ + T ++E+ + L DN IP
Sbjct: 861 CNVSSPIFKAGHSVALQMMFNTLVNSSW-GDSVELHANVTCNNED-SDLLEDNSATTIIP 918
Query: 916 VKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF---PMPEL 972
+ Y + + + + ++ P++ +++ Y +R S +P L
Sbjct: 919 ILYPINI-LIQDQEDSTLYVSFTPKGPKI--------HQVKHMYQVRIQPSIHDHNIPTL 969
Query: 973 KLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTIL 1032
+ + P S G P+ + + C +ED +++ + + G +
Sbjct: 970 EAVVGVPQPPSEG-PITHQWSVQMEPPVPCH---YEDL------ERLPDAAEPCLPGALF 1019
Query: 1033 DCNTCKFATITCNL--TSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVL 1090
C I + T + ++ S + + S S N + L NASL
Sbjct: 1020 RCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASLA- 1075
Query: 1091 SSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKME 1150
+ + D + + L++ +K+GFFKR LK+KME
Sbjct: 1076 ---------QVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1126
>ref|NP_002200.1| integrin alpha L precursor; antigen CD11A (p180), lymphocyte
function-associated antigen 1, alpha polypeptide [Homo
sapiens]
pir||S03308 cell surface glycoprotein CD11a precursor - human
emb|CAA68747.1| (Y00796) LFA-1 alpha subunit precursor (AA -25 to 1145) [Homo
sapiens]
Length = 1170
Score = 365 bits (927), Expect = 2e-99
Identities = 328/1200 (27%), Positives = 540/1200 (44%), Gaps = 149/1200 (12%)
Query: 1 FNVDVKNSMTFSGPVEDM-FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRG 59
+N+DV+ + +FS P FGY V Q G V++G+P G N TG +Y+C G G
Sbjct: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQCQSGTG 78
Query: 60 ESLPCVKLDLPVNTSIPNVTEVKENMT---FGSTLVTNP-NGGFLACGPLYAYRCGHLHY 115
LP VT N T G TL T+P +G LAC P + C Y
Sbjct: 79 HCLP--------------VTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTY 124
Query: 116 TTGICSDVSPTFQ--VVNSIAPVQEC-STQLDIVIVLDGSNSIYP--WDSVTAFLNDLLK 170
+G+C Q ++ QEC +D+V + DGS S+ P + + F+ D++K
Sbjct: 125 LSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMK 184
Query: 171 RMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTAR 230
++ Q VQ+ + EF+ + Y ++ A K V+ T T +
Sbjct: 185 KLS--NTSYQFAAVQFSTSYKTEFDFSDYVKWKDP-DALLKHVKHMLLLTNTFGAINYVA 241
Query: 231 KEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNL 290
E F E GAR KV++I+TDGE+ D+ + ++I R+ I I +
Sbjct: 242 TEVFREELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRYIIGI-----GKHF 290
Query: 291 STEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEM 349
T++ E + AS+P + F + D L + L ++I+ +E T+ Q SF ME+
Sbjct: 291 QTKESQETLHKFASKPASE-FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMEL 349
Query: 350 SQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLG 409
S +G SA S+ ++GAVGA DW G + KA ++ TF E A YLG
Sbjct: 350 SSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADL----QDDTFIGNEPLTPEVRAGYLG 405
Query: 410 YTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSILT 467
YTV + L +G PRY H G+V++++ G + +QT+ G QIGSYFG L
Sbjct: 406 YTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELC 465
Query: 468 TTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQH 527
D+D+D T++LL+GAP++ G ++ G+V++Y Q FE L+
Sbjct: 466 GVDVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG----------- 512
Query: 528 NSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRK 587
+ P G RFG AI A+ D+N DG D+ +GAPLE+ GAVYI++G +
Sbjct: 513 ------DPGYPLG-RFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSP 563
Query: 588 EYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMN 647
+ +QRI +++FG+SIHG DL GDGL DV +G + SR V + M+
Sbjct: 564 QPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMS 623
Query: 648 FEPNKVNIQKKNC--HMEGKETVCINATVCFEVK-LKSKEDTIYEADLQYRVTLDSLRQI 704
F P ++ + + C K +N T+CF++K L + A+L Y + LD R
Sbjct: 624 FSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLYPQFQGRLVANLTYTLQLDGHRTR 683
Query: 705 SRSFFSGTQERKVQRNITVRKS-ECTKHSFYM-LDKHDFQDSVRITLDFNLTDPEN---- 758
R F G + +++RNI V S CT SF+ + D + ++L+F+L + E
Sbjct: 684 RRGLFPGGR-HELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRD 742
Query: 759 --------GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDK 810
P+L SL + E IPF K+CG +KC ++L + + L + +
Sbjct: 743 QRAQGKDIPPILRPSLHSETWE-IPFEKNCGEDKKCEANLRVSFSPARSRALRL-TAFAS 800
Query: 811 FNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNIT 857
+V L++ N ++ AY + +H+ P L F +E ++ SCE + ++
Sbjct: 801 LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALS 860
Query: 858 CKVGYPFLRRGEMVTFKILFQ--FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIP 915
C V P + G V +++F N+S+ ++V ++ + T ++E+ + L DN IP
Sbjct: 861 CNVSSPIFKAGHSVALQMMFNTLVNSSW-GDSVELHANVTCNNED-SDLLEDNSATTIIP 918
Query: 916 VKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSF---PMPEL 972
+ Y + + + + ++ P++ +++ Y +R S +P L
Sbjct: 919 ILYPINI-LIQDQEDSTLYVSFTPKGPKI--------HQVKHMYQVRIQPSIHDHNIPTL 969
Query: 973 KLSISFPNMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTIL 1032
+ + P S G P+ + + C +ED +++ + + G +
Sbjct: 970 EAVVGVPQPPSEG-PITHQWSVQMEPPVPCH---YEDL------ERLPDAAEPCLPGALF 1019
Query: 1033 DCNTCKFATITCNL--TSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVL 1090
C I + T + ++ S + + S S N + L NASL
Sbjct: 1020 RCPVVFRQEILVQVIGTLELVGEIEASSMF---SLCSSLSISFNSSKHFHLYGSNASLA- 1075
Query: 1091 SSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKME 1150
+ + D + + L++ +K+GFFKR LK+KME
Sbjct: 1076 ---------QVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKME 1126
>ref|NP_032427.1| integrin alpha M (Cd11b); Mac-1 alpha; CD11B (p170); macrophage
antigen alpha; complement component receptor 3 alpha-a
(CR3A) [Mus musculus]
sp|P05555|ITAM_MOUSE CELL SURFACE GLYCOPROTEIN MAC-1 ALPHA SUBUNIT PRECURSOR (CR-3 ALPHA
CHAIN) (CD11B) (LEUKOCYTE ADHESION RECEPTOR MO1)
(INTEGRIN ALPHA-M)
pir||S00551 leukocyte surface glycoprotein Mac-1 alpha chain precursor - mouse
emb|CAA30479.1| (X07640) Mac-1 alpha-chain precursor (AA -16 to 1134) [Mus musculus]
Length = 1153
Score = 362 bits (919), Expect = 1e-98
Identities = 336/1206 (27%), Positives = 530/1206 (43%), Gaps = 133/1206 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D ++ MTF + FG V Q G V++ +P + N+TG +Y+C
Sbjct: 17 FNLDTEHPMTFQENAKG-FGQNVVQLG---GTSVVVAAPQEAKAVNQTGALYQCDYSTSR 72
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTL-VTNPNGGFLACGPLYAYRCGHLHYTTGI 119
P + L +P NM+ G +L V+ LACGP C Y G+
Sbjct: 73 CHP-IPLQVPPEAV---------NMSLGLSLAVSTVPQQLLACGPTVHQNCKENTYVNGL 122
Query: 120 C-----SDVSPTFQVVNSIAPVQECSTQ-LDIVIVLDGSNSIYPWD--SVTAFLNDLLKR 171
C + + P Q ++ +EC Q DIV ++DGS SI D + F++ ++++
Sbjct: 123 CYLFGSNLLRPPQQFPEAL---RECPQQESDIVFLIDGSGSINNIDFQKMKEFVSTVMEQ 179
Query: 172 MDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARK 231
+T ++QY + F N + I Q GR T TA G +
Sbjct: 180 FK--KSKTLFSLMQYSDEFRIHFTFNDFKRNPSPRSHVSPIKQLNGR-TKTASGIRKVVR 236
Query: 232 EAFTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNL 290
E F + GAR K++V++TDGE D K VI + + + R+ I + ++N+
Sbjct: 237 ELFHKTNGARENAAKILVVITDGEKFGDPLDYKDVIPEADRAGVIRYVIGVGNAFNKPQS 296
Query: 291 STEKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMS 350
E+ +IAS+P +H F V + AL TI L E+IFA+E T S +SFE EMS
Sbjct: 297 R-----RELDTIASKPAGEHVFQVDNFEALNTIQNQLQEKIFAIEGTQTGSTSSFEHEMS 351
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
Q GFSA + + +LG+VG++DW G + + + NTT V+S + +YLGY
Sbjct: 352 QEGFSASITSNGPLLGSVGSFDWAGGAFLYTSKDKVTFINTT-RVDSDMND----AYLGY 406
Query: 411 TVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTD 470
++ + + G PRY H G V+++R G + ++ G QIGSYFG+ L + D
Sbjct: 407 -ASAVILRNRVQSLVLGAPRYQHIGLVVMFRENFGTWEPHTSIKGSQIGSYFGASLCSVD 465
Query: 471 IDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSC 530
+D D NT+++L+GAP Y EK G+V V L + R +Q C + H
Sbjct: 466 MDADGNTNLILIGAPHYY--EKTRGGQVSVCPLPRGRARWQ----------CEALLHG-- 511
Query: 531 TTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSG-KTIRKEY 589
++ P G RFG A+ + D+N D D+ IGAP E ++ GAVYI++G+ ++ +
Sbjct: 512 ---DQGHPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFYGASIASLSASH 567
Query: 590 AQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFE 649
+ RI L++FGQS+ G DL DGL D+ +G G L ++ V ++ TM F
Sbjct: 568 SHRIIGAHFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGHLLLLRAQPVLRLEATMEFS 627
Query: 650 PNKVNIQKKNCHMEG-KETVCINATVCFEVKLKSKEDTIYEADLQ----YRVTLDSLRQI 704
P KV C + K VC V+ K+ +D + E D+Q Y + LD +R
Sbjct: 628 PKKVARSVFACQEQVLKNKDAGEVRVCLRVR-KNTKDRLREGDIQSTVTYDLALDPVRSR 686
Query: 705 SRSFFSGTQERKVQR-NITVRKSECTKHSFYMLDKHDFQDSVR-ITLDFNLT---DPENG 759
R+FF T+ +R + +C + D D DSV I L N T +P
Sbjct: 687 IRAFFDETKNNTRRRTQVFGLMQKCETLKLILPDCVD--DSVSPIILRLNYTLVGEPLRS 744
Query: 760 -----PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVS 814
PVL PF K+CGN C DLS+ ++ D L+V D FN+S
Sbjct: 745 FGNLRPVLAMDAQRFFTAMFPFEKNCGNDSICQDDLSITMSAMGLDTLVVGGPQD-FNMS 803
Query: 815 LTVKNTKDSAYNTRTIVHYSPNLVFSG--------------IEAIQKDSCESNH----NI 856
+T++N + +Y T+ V+Y L + ++ + S H +
Sbjct: 804 VTLRNDGEDSYGTQVTVYYPSGLSYRKDSASQNPLTKKPWFVKPAESSSSSEGHGALKST 863
Query: 857 TCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPV 916
T + +P VTF + F ++ N + L A SE + +PV
Sbjct: 864 TWNINHPIFPANSEVTFNVTFDVDSHASFGN-KLLLKAIVASENNMSRTHKTKFQLELPV 922
Query: 917 KYEVGLQFYSSASEY-HISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMP---EL 972
KY + + S S +++ A+E +VI Y G +P
Sbjct: 923 KYAIYMIVTSDESSIRYLNFTASEMTSKVIQHQ----------YQFNNLGQRSLPVSVVF 972
Query: 973 KLSISFPNMTSNGYP-VLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTI 1031
+ + N+T +P V++ LSS+ C P S D L+R +
Sbjct: 973 WIPVQINNVTVWDHPQVIFSQNLSSA----CHTEQKSPPHS--------NFRDQLERTPV 1020
Query: 1032 LDCNTCKFATITCNLTSSDISQV-NVSL--ILWKPTFIKSYFSSLNLTIRGELRSENASL 1088
L+C+ I C+L S + ++ NV+L L +IK+ L L E+ +++
Sbjct: 1021 LNCSVAVCKRIQCDLPSFNTQEIFNVTLKGNLSFDWYIKTSHGHLLLVSSTEILFNDSAF 1080
Query: 1089 VL---SSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPL 1145
L S + + ++ + VPL I +K+GFFKR
Sbjct: 1081 ALLPGQESYVRSKTETKVEPYEVHNPVPL--IVGSSIGGLVLLALITAGLYKLGFFKRQY 1138
Query: 1146 KKKMEK 1151
K M +
Sbjct: 1139 KDMMNE 1144
>gb|AAC31672.1| (AC002310) leukocyte function-associated molecule-1 alpha subunit
[Homo sapiens]
Length = 1223
Score = 360 bits (913), Expect = 7e-98
Identities = 289/967 (29%), Positives = 462/967 (46%), Gaps = 112/967 (11%)
Query: 1 FNVDVKNSMTFSGPVEDM-FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRG 59
+N+DV+ + +FS P FGY V Q G V++G+P G N TG +Y+C G G
Sbjct: 26 YNLDVRGARSFSPPRAGRHFGYRVLQV----GNGVIVGAPGEG---NSTGSLYQCQSGTG 78
Query: 60 ESLPCVKLDLPVNTSIPNVTEVKENMT---FGSTLVTNP-NGGFLACGPLYAYRCGHLHY 115
LP VT N T G TL T+P +G LAC P + C Y
Sbjct: 79 HCLP--------------VTLRGSNYTSKYLGMTLATDPTDGSILACDPGLSRTCDQNTY 124
Query: 116 TTGICSDVSPTFQ--VVNSIAPVQEC-STQLDIVIVLDGSNSIYP--WDSVTAFLNDLLK 170
+G+C Q ++ QEC +D+V + DGS S+ P + + F+ D++K
Sbjct: 125 LSGLCYLFRQNLQGPMLQGRPGFQECIKGNVDLVFLFDGSMSLQPDEFQKILDFMKDVMK 184
Query: 171 RMDIGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTAR 230
++ Q VQ+ + EF+ + Y ++ A K V+ T T +
Sbjct: 185 KLS--NTSYQFAAVQFSTSYKTEFDFSDYVKWKDP-DALLKHVKHMLLLTNTFGAINYVA 241
Query: 231 KEAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNL 290
E F E GAR KV++I+TDGE+ D+ + ++I R+ I I +
Sbjct: 242 TEVFREELGARPDATKVLIIITDGEATDSGNIDAA------KDIIRYIIGI-----GKHF 290
Query: 291 STEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEM 349
T++ E + AS+P + F + D L + L ++I+ +E T+ Q SF ME+
Sbjct: 291 QTKESQETLHKFASKPASE-FVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMEL 349
Query: 350 SQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLG 409
S +G SA S+ ++GAVGA DW G + KA ++ TF E A YLG
Sbjct: 350 SSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADL----QDDTFIGNEPLTPEVRAGYLG 405
Query: 410 YTVNSATASSGDVLYIAGQPRYNHTGQVIIYRMEDG--NIKILQTLSGEQIGSYFGSILT 467
YTV + L +G PRY H G+V++++ G + +QT+ G QIGSYFG L
Sbjct: 406 YTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELC 465
Query: 468 TTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQH 527
D+D+D T++LL+GAP++ G ++ G+V++Y Q FE L+
Sbjct: 466 GVDVDQDGETELLLIGAPLFYGEQRG--GRVFIYQRRQLGFEEVSELQG----------- 512
Query: 528 NSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRK 587
+ P G RFG AI A+ D+N DG D+ +GAPLE+ GAVYI++G +
Sbjct: 513 ------DPGYPLG-RFGEAITALTDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSP 563
Query: 588 EYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMN 647
+ +QRI +++FG+SIHG DL GDGL DV +G + SR V + M+
Sbjct: 564 QPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMS 623
Query: 648 FEPNKVNIQKKNC--HMEGKETVCINATVCFEVK-LKSKEDTIYEADLQYRVTLDSLRQI 704
F P ++ + + C K +N T+CF++K L + A+L Y + LD R
Sbjct: 624 FSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTR 683
Query: 705 SRSFFSGTQERKVQRNITVRKS-ECTKHSFYM-LDKHDFQDSVRITLDFNLTDPEN---- 758
R F G + +++RNI V S CT SF+ + D + ++L+F+L + E
Sbjct: 684 RRGLFPGGR-HELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRD 742
Query: 759 --------GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDK 810
P+L SL + E IPF K+CG +KC ++L + + L + +
Sbjct: 743 QRAQGKDIPPILRPSLHSETWE-IPFEKNCGEDKKCEANLRVSFSPARSRALRL-TAFAS 800
Query: 811 FNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNIT 857
+V L++ N ++ AY + +H+ P L F +E ++ SCE + ++
Sbjct: 801 LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALS 860
Query: 858 CKVGYPFLRRGEMVTFKILFQ--FNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIP 915
C V P + G V +++F N+S+ ++V ++ + T ++E+ + L DN IP
Sbjct: 861 CNVSSPIFKAGHSVALQMMFNTLVNSSW-GDSVELHANVTCNNED-SDLLEDNSATTIIP 918
Query: 916 VKYEVGL 922
+ Y + +
Sbjct: 919 ILYPINI 925
>pir||RWHU1C cell surface glycoprotein CD11c precursor - human
Length = 1163
Score = 358 bits (909), Expect = 2e-97
Identities = 326/1204 (27%), Positives = 534/1204 (44%), Gaps = 133/1204 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + F FG +V QY N WV++G+P N+TG +Y+C G
Sbjct: 20 FNLDTEELTAFRVDSAG-FGDSVVQYANS---WVVVGAPQKITAANQTGGLYQCGYSTGA 75
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
P + L +P P + ++ ST T+P+ LACGP + CG Y TG+C
Sbjct: 76 CEP-IGLQVP-----PEAVNMSLGLSLAST--TSPSQ-LLACGPTVHHECGRNMYLTGLC 126
Query: 121 SDVSPTFQVVNSIAPVQECSTQ-LDIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPK 177
+ PT QEC Q DIV ++DGS SI + T F+ ++ +
Sbjct: 127 FLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ--RP 184
Query: 178 QTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEA 237
TQ ++Q+ F ++ T L + Q G T TA F +
Sbjct: 185 STQFSLMQFSNKFQTHFTFEEFRRTSNPLSLLASVHQLQGF-TYTATAIQNVVHRLFHAS 243
Query: 238 RGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAI-LGSYNRGNLSTEKF 295
GARR K+++++TDG+ D+ K VI + I R++I + L NR +
Sbjct: 244 YGARRDATKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSW----- 298
Query: 296 VEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFS 355
+E+ IAS+P+++H F V D AL I L E+IFA+E T S++SFE+EM+Q GFS
Sbjct: 299 -KELNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFS 357
Query: 356 AHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSA 415
A ++ D +LGAVG++ W+G + + + TF S + + SYLGY+ A
Sbjct: 358 AVFTPDGPVLGAVGSFTWSGGAFLYPPNM-----SPTFINMSQENVDMRDSYLGYSTELA 412
Query: 416 TASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDS 475
L + G PRY HTG+ +I+ ++ ++G QIGSYFG+ L + D+D D
Sbjct: 413 LWKGVQSL-VLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDTDG 471
Query: 476 NTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENK 535
+TD++L+GAP Y E+ G+V V L + ++ C + + +
Sbjct: 472 STDLVLIGAPHYY--EQTRGGQVSVCPLPR----------GWRRWWCDAVLYG-----EQ 514
Query: 536 NEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYAQRIP 594
P G RFG A+ + D+N D D+VIGAP E+++ GAVY++HG G +I ++QRI
Sbjct: 515 GHPWG-RFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIA 573
Query: 595 SGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVN 654
L++FGQ++ G DL DGL D+ +G G L +R V V V+M F P ++
Sbjct: 574 GSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPAEIP 633
Query: 655 IQKKNCHME-GKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSL----RQISRSFF 709
C + E + + +C + +SK + + DLQ VTLD R R+ F
Sbjct: 634 RSAFECREQVVSEQTLVQSNICLYIDKRSK-NLLGSRDLQSSVTLDLALDPGRLSPRATF 692
Query: 710 SGTQERKVQR-NITVRKSECTKHSFYMLDKHDFQDSVR-ITLDFNLT--------DPENG 759
T+ R + R + K+ C +F +L +DSV ITL N T
Sbjct: 693 QETKNRSLSRVRVLGLKAHC--ENFNLLLPSCVEDSVTPITLRLNFTLVGKPLLAFRNLR 750
Query: 760 PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKN 819
P+L +PF K+CG C +L + + L+V S N + N + V N
Sbjct: 751 PMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGS-NLELNAEVMVWN 809
Query: 820 TKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCES-------NHNITCKVGYPF 864
+ +Y T + L + + QK +C+S + +C++ +
Sbjct: 810 DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLI 869
Query: 865 LRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQF 924
R G +TF F + ++ + + L+A SE S + +PVKY V
Sbjct: 870 FRGGAQITFLATFDVSPKAVLGD-RLLLTANVSSENNTPRTSKTTFQLELPVKYAV---- 924
Query: 925 YSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF-PNMTS 983
+ ++++E + +N +E E ++ + + +L +SI+F +
Sbjct: 925 -------YTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQRDLPVSINFWVPVEL 977
Query: 984 NGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRGTILDCNTCKFA 1040
N V +S +N + R +S K ++D H+++ +LDC+
Sbjct: 978 NQEAVWMDVEVSHPQNPSLR---------CSSEKIAPPASDFLAHIQKNPVLDCSIAGCL 1028
Query: 1041 TITCNLTSSDISQV-------NVSL-----ILWKPTFIKSYFS-SLNLTIRGELRSENAS 1087
C++ S + + N+S IL K + S + + ++ +L + A
Sbjct: 1029 RFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQLPGQEAF 1088
Query: 1088 LVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKK 1147
+ + + + K + PL I +K+GFFKR K+
Sbjct: 1089 M-------RAQTTTVLEKYKVHNPTPL--IVGSSIGGLLLLALITAVLYKVGFFKRQYKE 1139
Query: 1148 KMEK 1151
ME+
Sbjct: 1140 MMEE 1143
>gb|AAF21241.1|AF021334_1 (AF021334) alpha D integrin [Rattus norvegicus]
Length = 1161
Score = 358 bits (908), Expect = 3e-97
Identities = 324/1202 (26%), Positives = 535/1202 (43%), Gaps = 138/1202 (11%)
Query: 2 NVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGES 61
N+DV+ + F FG TV Q+ G +++G+PL N+TG +Y C G
Sbjct: 21 NLDVEEPIVFREDAAS-FGQTVVQFG---GSRLVVGAPLEAVAVNQTGRLYDCAPATGMC 76
Query: 62 LPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGG-FLACGPLYAYRCGHLHYTTGIC 120
P V L P+ NM+ G +LVT N LACGP C Y G C
Sbjct: 77 QPIV-LRSPLEAV---------NMSLGLSLVTATNNAQLLACGPTAQRACVKNMYAKGSC 126
Query: 121 SDVSPTFQVVNSI-APVQECSTQ-LDIVIVLDGSNSIYPWDSVTAFLNDLLKRM--DIGP 176
+ + Q + ++ A + EC Q +DI ++DGS SI D A + D +K + +
Sbjct: 127 LLLGSSLQFIQAVPASMPECPRQEMDIAFLIDGSGSINQRDF--AQMKDFVKALMGEFAS 184
Query: 177 KQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTE 236
T ++QY + F ++ + + IVQ G T TA G T +E F
Sbjct: 185 TSTLFSLMQYSNILKTHFTFTEFKNILDPQSLVDPIVQLQGL-TYTATGIRTVMEELFHS 243
Query: 237 ARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKF 295
G+R+ KK+++++TDG+ + D VI + I R++I + ++
Sbjct: 244 KNGSRKSAKKILLVITDGQKYRDPLEYSDVIPAADKAGIIRYAIGVGDAFQEPTA----- 298
Query: 296 VEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFS 355
++E+ +I S P + H F V + AL +I + L E+IFA+E T +S++SF+ EMSQ GFS
Sbjct: 299 LKELNTIGSAPPQDHVFKVGNFAALRSIQRQLQEKIFAIEGTQSRSSSSFQHEMSQEGFS 358
Query: 356 AHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNT--TFNVESTKKNEPLASYLGYTVN 413
+ + D +LGAVG++ W+G + P NT TF S + + SYLGY+
Sbjct: 359 SALTSDGPVLGAVGSFSWSG-------GAFLYPPNTRPTFINMSQENVDMRDSYLGYS-T 410
Query: 414 SATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDK 473
+ G I G PR+ HTG+V+I+ E + + + G QIGSYFG+ L + D+D+
Sbjct: 411 AVAFWKGVHSLILGAPRHQHTGKVVIFTQEARHWRPKSEVRGTQIGSYFGASLCSVDVDR 470
Query: 474 DSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 533
D +TD++L+GAP Y E+ G+V V+ + R +Q C + H
Sbjct: 471 DGSTDLVLIGAPHYY--EQTRGGQVSVFPVPGVRGRWQ----------CEATLHG----- 513
Query: 534 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGK-TIRKEYAQR 592
+ P G RFG A+ + D+N D D+ IGAP E++ GAVYI+HG+ + I +QR
Sbjct: 514 EQGHPWG-RFGVALTVLGDVNGDNLADVAIGAPGEEESRGAVYIFHGASRLEIMPSPSQR 572
Query: 593 IPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNK 652
+ L++FGQS+ G DL DGL D+ +G G L S + V++++ F P +
Sbjct: 573 VTGSQLSLRLQYFGQSLSGGQDLTQDGLVDLAVGAQGHVLLLRSLPLLKVELSIRFAPME 632
Query: 653 VNIQKKNCHMEGKETV--CINATVCFEVKLKSKEDTI--YEADLQYRVTLDSLRQISRSF 708
V C E TV ATVC V K D + + ++Y + LD R ISR+
Sbjct: 633 VAKAVYQC-WERTPTVLEAGEATVCLTVH-KGSPDLLGNVQGSVRYDLALDPGRLISRAI 690
Query: 709 FSGTQERKVQRNITVRKSE-CTKHSFYMLD-KHDFQDSVRITLDFNL----TDPEN-GPV 761
F T+ + T+ + C + D D + + L+F+L P N PV
Sbjct: 691 FDETKNCTLTGRKTLGLGDHCETVKLLLPDCVEDAVSPIILRLNFSLVRDSASPRNLHPV 750
Query: 762 LDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTK 821
L + + +PF K+C + C DL + + +L+V + + V++TV N
Sbjct: 751 LAVGSQDHITASLPFEKNCKQELLCEGDLGISFNFSGLQVLVV-GGSPELTVTVTVWNEG 809
Query: 822 DSAYNTRTIVHYSPNLVFSGIEAIQKD-------SCESN-------HNITCKVGYPFLRR 867
+ +Y T +Y L + + Q+ +CE+ + +C + +P R
Sbjct: 810 EDSYGTLVKFYYPAGLSYRRVTGTQQPHQYPLRLACEAEPAAQEDLRSSSCSINHPIFRE 869
Query: 868 GEMVTFKILFQFN-TSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYS 926
G TF I F + ++L + + + A+S++ +P + + +PVKY V
Sbjct: 870 GAKTTFMITFDVSYKAFLGDRLLLRAKASSENNKP--DTNKTAFQLELPVKYTV------ 921
Query: 927 SASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF-PNMTSNG 985
Y + ++ V S+ G + R + P+ +L + ++F + NG
Sbjct: 922 ----YTLISRQEDSTNHVNFSSSHGGRRQEAAHRYRVNNLSPL-KLAVRVNFWVPVLLNG 976
Query: 986 YPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHL---KRGTILDCNTCKFATI 1042
V T S ++ +C S K + D L +R ++LDC+
Sbjct: 977 VAVWDVTLSSPAQGVSC-----------VSQMKPPQNPDFLTQIQRRSVLDCSIADCLHF 1025
Query: 1043 TCNLTSSDISQVNVSLIL-------W-------KPTFIKSYFSSLNLTIRGELRSENASL 1088
C++ S DI Q + IL W K + + + ++ +L + A L
Sbjct: 1026 RCDIPSLDI-QDELDFILRGNLSFGWVSQTLQEKVLLVSEAEITFDTSVYSQLPGQEAFL 1084
Query: 1089 VLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKK 1148
E + P++++ +K+GFFKR K+
Sbjct: 1085 RAQVETTLEEYVVY---------EPIFLVAGSSVGGLLLLALITVVLYKLGFFKRQYKEM 1135
Query: 1149 ME 1150
++
Sbjct: 1136 LD 1137
>ref|NP_000878.1| integrin alpha X precursor [Homo sapiens]
sp|P20702|ITAX_HUMAN LEUKOCYTE ADHESION GLYCOPROTEIN P150,95 ALPHA CHAIN PRECURSOR
(LEUKOCYTE ADHESION RECEPTOR P150,95) (CD11C) (LEU M5)
(INTEGRIN ALPHA-X)
emb|CAA68283.1| (Y00093) leukocyte adhesion glycoprotein [Homo sapiens]
gb|AAA59180.1| (M81695) ITGAX [Homo sapiens]
Length = 1163
Score = 357 bits (907), Expect = 3e-97
Identities = 326/1204 (27%), Positives = 534/1204 (44%), Gaps = 133/1204 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + F FG +V QY N WV++G+P N+TG +Y+C G
Sbjct: 20 FNLDTEELTAFRVDSAG-FGDSVVQYANS---WVVVGAPQKITAANQTGGLYQCGYSTGA 75
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
P + L +P P + ++ ST T+P+ LACGP + CG Y TG+C
Sbjct: 76 CEP-IGLQVP-----PEAVNMSLGLSLAST--TSPSQ-LLACGPTVHHECGRNMYLTGLC 126
Query: 121 SDVSPTFQVVNSIAPVQECSTQ-LDIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPK 177
+ PT QEC Q DIV ++DGS SI + T F+ ++ +
Sbjct: 127 FLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ--RP 184
Query: 178 QTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEA 237
TQ ++Q+ F ++ T L + Q G T TA F +
Sbjct: 185 STQFSLMQFSNKFQTHFTFEEFRRTSNPLSLLASVHQLQGF-TYTATAIQNVVHRLFHAS 243
Query: 238 RGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAI-LGSYNRGNLSTEKF 295
GARR K+++++TDG+ D+ K VI + I R++I + L NR +
Sbjct: 244 YGARRDATKILIVITDGKKEGDSLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSW----- 298
Query: 296 VEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFS 355
+E+ IAS+P+++H F V D AL I L E+IFA+E T S++SFE+EM+Q GFS
Sbjct: 299 -KELNDIASKPSQEHIFKVEDFDALKDIQNQLKEKIFAIEGTETTSSSSFELEMAQEGFS 357
Query: 356 AHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSA 415
A ++ D +LGAVG++ W+G + + + TF S + + SYLGY+ A
Sbjct: 358 AVFTPDGPVLGAVGSFTWSGGAFLYPPNM-----SPTFINMSQENVDMRDSYLGYSTELA 412
Query: 416 TASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDS 475
L + G PRY HTG+ +I+ ++ ++G QIGSYFG+ L + D+D D
Sbjct: 413 LWKGVQSL-VLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGASLCSVDVDTDG 471
Query: 476 NTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENK 535
+TD++L+GAP Y E+ G+V V L + ++ C + + +
Sbjct: 472 STDLVLIGAPHYY--EQTRGGQVSVCPLPR----------GWRRWWCDAVLYG-----EQ 514
Query: 536 NEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYAQRIP 594
P G RFG A+ + D+N D D+VIGAP E+++ GAVY++HG G +I ++QRI
Sbjct: 515 GHPWG-RFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIA 573
Query: 595 SGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVN 654
L++FGQ++ G DL DGL D+ +G G L +R V V V+M F P ++
Sbjct: 574 GSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIPAEIP 633
Query: 655 IQKKNCHME-GKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSL----RQISRSFF 709
C + E + + +C + +SK + + DLQ VTLD R R+ F
Sbjct: 634 RSAFECREQVVSEQTLVQSNICLYIDKRSK-NLLGSRDLQSSVTLDLALDPGRLSPRATF 692
Query: 710 SGTQERKVQR-NITVRKSECTKHSFYMLDKHDFQDSVR-ITLDFNLT--------DPENG 759
T+ R + R + K+ C +F +L +DSV ITL N T
Sbjct: 693 QETKNRSLSRVRVLGLKAHC--ENFNLLLPSCVEDSVTPITLRLNFTLVGKPLLAFRNLR 750
Query: 760 PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKN 819
P+L +PF K+CG C +L + + L+V S N + N + V N
Sbjct: 751 PMLAALAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGS-NLELNAEVMVWN 809
Query: 820 TKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCES-------NHNITCKVGYPF 864
+ +Y T + L + + QK +C+S + +C++ +
Sbjct: 810 DGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLI 869
Query: 865 LRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQF 924
R G +TF F + ++ + + L+A SE S + +PVKY V
Sbjct: 870 FRGGAQITFLATFDVSPKAVLGD-RLLLTANVSSENNTPRTSKTTFQLELPVKYAV---- 924
Query: 925 YSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF-PNMTS 983
+ ++++E + +N +E E ++ + + +L +SI+F +
Sbjct: 925 -------YTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQRDLPVSINFWVPVEL 977
Query: 984 NGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRGTILDCNTCKFA 1040
N V +S +N + R +S K ++D H+++ +LDC+
Sbjct: 978 NQEAVWMDVEVSHPQNPSLR---------CSSEKIAPPASDFLAHIQKNPVLDCSIAGCL 1028
Query: 1041 TITCNLTSSDISQV-------NVSL-----ILWKPTFIKSYFS-SLNLTIRGELRSENAS 1087
C++ S + + N+S IL K + S + + ++ +L + A
Sbjct: 1029 RFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQLPGQEAF 1088
Query: 1088 LVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKK 1147
+ + + + K + PL I +K+GFFKR K+
Sbjct: 1089 M-------RAQTTTVLEKYKVHNPTPL--IVGSSIGGLLLLALITAVLYKVGFFKRQYKE 1139
Query: 1148 KMEK 1151
ME+
Sbjct: 1140 MMEE 1143
>gb|AAF81280.1| (AF268593) integrin beta 2 alpha subunit; CD11b [Rattus norvegicus]
Length = 1151
Score = 353 bits (895), Expect = 9e-96
Identities = 322/1195 (26%), Positives = 518/1195 (42%), Gaps = 113/1195 (9%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D +N MTF FG +V Q V++ +P + N+TG +Y+C
Sbjct: 17 FNLDTENPMTFQENASG-FGQSVIQLGETR---VVVAAPQEVKAVNQTGALYQCDYSTNR 72
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
P + L +P P + ++ +T V LACGP C Y G+C
Sbjct: 73 CDP-IPLQVP-----PEAVNMSLGLSLAATTVPPQ---LLACGPTVHQNCKENTYVNGLC 123
Query: 121 SDVSPTFQVVNSIAP--VQECSTQ-LDIVIVLDGSNSIYPWD--SVTAFLNDLLKRMDIG 175
P ++ C Q +I ++DGS SI D + F++ ++ +
Sbjct: 124 YLFGSNLLRKPQQFPEALRGCPQQESNIAFLIDGSGSINTIDFQKMKEFVSTVMDQFQ-- 181
Query: 176 PKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFT 235
+T ++QY + F N + + + I Q GR T TA G +E F
Sbjct: 182 KSKTLFSLMQYSDEFRTHFTFNDFKRNPDPKSHVRPIRQLNGR-TKTASGIRKVVRELFQ 240
Query: 236 EARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEK 294
+ GAR K++V++TDGE D + VI + E+ I R+ I + ++++
Sbjct: 241 KINGARDNAAKILVVITDGEKFGDPLNYEDVIPEAEEAGIIRYVIGVGNAFHKPQSR--- 297
Query: 295 FVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGF 354
E+ +IAS+P H F V + AL TI L E+IFA+E T S +SFE EMSQ GF
Sbjct: 298 --RELDTIASKPAGDHVFQVDNFEALNTIRNQLQEKIFAIEGTQTGSTSSFEHEMSQEGF 355
Query: 355 SAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNS 414
SA + + +LG+VG++DW G + + NTT ++S + +YLGY S
Sbjct: 356 SAAITSNGPLLGSVGSFDWAGGAFLYPSKDKASFINTT-RIDSDMND----AYLGYA--S 408
Query: 415 ATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDK 473
A S V + G PRY H G V++++ G + + G QIGSYFG+ L + D+D
Sbjct: 409 AVISRNRVQSLVLGAPRYQHIGLVVMFKQNFGAWEPHTDIKGSQIGSYFGASLCSVDMDA 468
Query: 474 DSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTE 533
D NT+++L+GAP + EK G+V V L + R +Q C + H
Sbjct: 469 DGNTNLILIGAPHHY--EKTRGGQVSVCPLPRGRARWQ----------CEAILHG----- 511
Query: 534 NKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSG-KTIRKEYAQR 592
++ P G RFG A+ + D+N D D+ IGAP E ++ GAVYI+HG+ +I ++QR
Sbjct: 512 DQGHPWG-RFGAALTVLGDVNGDKLTDVAIGAPGEQENQGAVYIFHGASVASISTPHSQR 570
Query: 593 IPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNK 652
I L++FGQS+ G DL DGL D+ +G G L ++ V ++ TM F P
Sbjct: 571 IAGARFSPGLQYFGQSLSGGKDLTMDGLMDLAVGAQGRLLLIRAQPVLRLEATMEFSPKN 630
Query: 653 VNIQKKNCHMEG-KETVCINATVCFEVKLKSKEDTIYEADLQYRVT----LDSLRQISRS 707
+ C E K VC +V+ K+ +D + E D+Q VT LD R + R+
Sbjct: 631 LARSVFACQEEVVKNKDAGEVRVCLQVR-KNTKDRLREGDIQSTVTYDLALDPGRSVVRA 689
Query: 708 FFSGTQERKVQR-NITVRKSECTKHSFYMLDKHDFQDS-VRITLDFNL------TDPENG 759
FF T+ ++R + +C + D D S + + L++ L + +
Sbjct: 690 FFDETKNGILRRIRVFGLTQKCETLKLILPDCVDNSVSPIILRLNYTLVGEPLRSSRDLR 749
Query: 760 PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKN 819
PVL PF K+CGN C DLS+ V++T + L+V D F+VS+T++N
Sbjct: 750 PVLAMEAQRIFTAMFPFEKNCGNDTICQDDLSITVSSTRVNTLVVGDSRD-FDVSVTLRN 808
Query: 820 TKDSAYNTRTIVHYSPNLVFSGIEAIQKDSCESNHNITCK----------------VGYP 863
+ +Y T+ +Y L + + A Q + + + + +P
Sbjct: 809 DGEDSYGTKVTCYYPSGLSYRKVSASQNQFSKKPWRVIAEPSSSEGQGVLKSTIWDINHP 868
Query: 864 FLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQ 923
VTF + F ++ + N + L SE + +PVKY + +
Sbjct: 869 IFPANSEVTFNVTFDVDSDASLGN-KLLLKVVVTSENNVSRTDKTESQLELPVKYAIYMV 927
Query: 924 FYSSASEY-HISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPNMT 982
S S +++ A+E +VI N + + P+ K++I P
Sbjct: 928 VTSGESSIKYLNFTASEMTSKVIQHQYQFNNLGQRSFPVSVVFWIPVQINKVTIWDPPQ- 986
Query: 983 SNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATI 1042
V + LSS CR + D L+R +L+C+ I
Sbjct: 987 -----VTFSQNLSSV----CRTE--------QKSPSHSKFQDELERTPVLNCSVAVCKRI 1029
Query: 1043 TCNL---TSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQ---K 1096
C++ S +I V + L +I++ L L E+ +++ L + K
Sbjct: 1030 QCDIPSFNSKEIFNVTLQGNLLFDWYIETSHDHLLLVSTAEILFNDSAFALLPGQETFVK 1089
Query: 1097 RELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKMEK 1151
+ ++ + VPL I +K+GFFKR K M +
Sbjct: 1090 AQTETKVEPYTVHNPVPL--IVGSSVGGLVLLALITAGLYKLGFFKRQYKDMMNE 1142
>gb|AAA51620.1| (M29487) integrin alpha subunit precursor [Homo sapiens]
Length = 1163
Score = 349 bits (885), Expect = 1e-94
Identities = 324/1208 (26%), Positives = 530/1208 (43%), Gaps = 141/1208 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + F FG +V QY N WV++G+P N+TG +Y+C G
Sbjct: 20 FNLDTEELTAFRVDSAG-FGDSVVQYANS---WVVVGAPQKITAANQTGGLYQCGYSTGA 75
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
P + L +P P + ++ ST T+P+ LACGP + CG Y TG+C
Sbjct: 76 CEP-IGLQVP-----PEAVNMSLGLSLAST--TSPSQ-LLACGPTVHHECGRNMYLTGLC 126
Query: 121 SDVSPTFQVVNSIAPVQECSTQ-LDIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPK 177
+ PT QEC Q DIV ++DGS SI + T F+ ++ +
Sbjct: 127 FLLGPTQLTQRLPVSRQECPRQEQDIVFLIDGSGSISSRNFATMMNFVRAVISQFQ--RP 184
Query: 178 QTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEA 237
TQ ++Q+ ++ T L + Q G T TA F +
Sbjct: 185 STQFSLMQFSNKFQTHLTFEEFRRTSNPLSLLASVHQLQGF-TYTATAIQNVVHRLFHAS 243
Query: 238 RGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAI-LGSYNRGNLSTEKF 295
GARR K+++++TDG+ D K VI + I R++I + L NR +
Sbjct: 244 YGARRDATKILIVITDGKKEGDTLDYKDVIPMADAAGIIRYAIGVGLAFQNRNSW----- 298
Query: 296 VEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFS 355
+E+ IAS+P+++H F V D AL I L E+IF +E T S++SFE+EM+Q GFS
Sbjct: 299 -KELNDIASKPSQEHIFKVEDFDALKDIQTQLREKIFPIEGTETTSSSSFELEMAQEGFS 357
Query: 356 AHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSA 415
A ++ D +LGAVG++ W+G + + + TF S + + SYLGY+ A
Sbjct: 358 AVFTPDGPVLGAVGSFTWSGGAFLYPPNM-----SPTFINMSQENVDMRDSYLGYSTELA 412
Query: 416 TASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDS 475
L + G PRY HTG+ +I+ ++ ++G QIGSYFG L + D+D D
Sbjct: 413 LWKGVQSL-VLGAPRYQHTGKAVIFTQVSRQWRMKAEVTGTQIGSYFGPSLCSVDVDSDG 471
Query: 476 NTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPI----KQTCCSSRQHNSCT 531
+TD++L+G P Y QTR Q+S+ P+ ++ C + +
Sbjct: 472 STDLVLIGPPHY---------------YEQTR-GAQVSVCPLPRGWRRWWCDAVLYG--- 512
Query: 532 TENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYA 590
+ P G RFG A+ + D+N D D+VIGAP E+++ GAVY++HG G +I ++
Sbjct: 513 --EQGHPWG-RFGAALTVLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHS 569
Query: 591 QRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEP 650
QRI L++FGQ++ G DL DGL D+ +G G L +R V V V+M F P
Sbjct: 570 QRIAGSQLSSRLQYFGQALSGGQDLTQDGLVDLAVGARGQVLLLRTRPVLWVGVSMQFIP 629
Query: 651 NKVNIQKKNCHME-GKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSL----RQIS 705
++ C + E + + +C + +SK + + DLQ VTLD R
Sbjct: 630 AEIPRSAFECREQVVSEQTLVQSNICLYIDKRSK-NLLGSRDLQSSVTLDLALDPGRLSP 688
Query: 706 RSFFSGTQERKVQR-NITVRKSECTKHSFYMLDKHDFQDSVR-ITLDFNLT--------D 755
R+ F T+ R + R + K+ C +F +L +DSV ITL N T
Sbjct: 689 RATFQETKNRSLSRVRVLGLKAHC--ENFNLLLPSCVEDSVTPITLRLNFTLVGKPLLAF 746
Query: 756 PENGPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSL 815
P+L +PF K+CG C +L + + L+V S N + N +
Sbjct: 747 RNLRPMLAADAQRYFTASLPFEKNCGADHICQDNLGISFSFPGLKSLLVGS-NLELNAEV 805
Query: 816 TVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCES-------NHNITCKV 860
V N + +Y T + L + + QK +C+S + +C++
Sbjct: 806 MVWNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRI 865
Query: 861 GYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEV 920
+ R G +TF F + ++ + + L+A SE S + +PVKY V
Sbjct: 866 NHLIFRGGAQITFLATFDVSPKAVLGD-RLLLTANVSSENNTPRTSKTTFQLELPVKYAV 924
Query: 921 GLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF-P 979
+ ++++E + +N +E E ++ + + +L +SI+F
Sbjct: 925 -----------YTVVSSHEQFTKYLNFSESEEKESHVAMHRYQVNNLGQRDLPVSINFWV 973
Query: 980 NMTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTD---HLKRGTILDCNT 1036
+ N V +S +N + R +S K ++D H+++ +LDC+
Sbjct: 974 PVELNQEAVWMDVEVSLPQNPSLR---------CSSEKIAGPASDFLAHIQKNPVLDCSI 1024
Query: 1037 CKFATITCNLTSSDISQV-------NVSL-----ILWKPTFIKSYFS-SLNLTIRGELRS 1083
C++ S + + N+S IL K + S + + ++ +L
Sbjct: 1025 AGCLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAEITFDTSVYSQLPG 1084
Query: 1084 ENASLVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKR 1143
+ A + + + + K + PL I +K+GFFKR
Sbjct: 1085 QEAFM-------RAQTTTVLEKYKVHNPTPL--IVGSSIGGLLLLALITAVLYKVGFFKR 1135
Query: 1144 PLKKKMEK 1151
K+ ME+
Sbjct: 1136 QYKEMMEE 1143
>gb|AAB38547.1| (U37028) leukointegrin alpha d chain [Homo sapiens]
Length = 1162
Score = 347 bits (881), Expect = 4e-94
Identities = 317/1195 (26%), Positives = 532/1195 (43%), Gaps = 119/1195 (9%)
Query: 1 FNVDVKNSMTFSGPVEDM--FGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGR 58
FN+DV+ F ED FG +V Q+ G +++G+PL N+TG +Y C
Sbjct: 18 FNLDVEEPTIFQ---EDAGGFGQSVVQFG---GSRLVVGAPLEVVAANQTGRLYDCAAAT 71
Query: 59 GESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGG-FLACGPLYAYRCGHLHYTT 117
G P +P++ V NM+ G TL + NG LACGP CG Y+
Sbjct: 72 GMCQP-----IPLHIRPEAV-----NMSLGLTLAASTNGSRLLACGPTLHRVCGENSYSK 121
Query: 118 GICSDVSPTFQVVNSIAPVQ-ECSTQ-LDIVIVLDGSNSI--YPWDSVTAFLNDLLKRMD 173
G C + ++++ ++ EC Q +DIV ++DGS SI ++ + F+ ++ + +
Sbjct: 122 GSCLLLGSRWEIIQTVPDATPECPHQEMDIVFLIDGSGSIDQNDFNQMKGFVQAVMGQFE 181
Query: 174 IGPKQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEA 233
T ++QY + F ++ ++ IVQ G T TA G T +
Sbjct: 182 --GTDTLFALMQYSNLLKIHFTFTQFRTSPSQQSLVDPIVQLKGL-TFTATGILTVVTQL 238
Query: 234 FTEARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLST 292
F GAR+ KK+++++TDG+ + D VI E I R++I + G +G +
Sbjct: 239 FHHKNGARKSAKKILIVITDGQKYKDPLEYSDVIPQAEKAGIIRYAIGV-GHAFQGPTAR 297
Query: 293 EKFVEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQT 352
+ E+ +I+S P + H F V + AL +I K L E+I+A+E T ++++SF+ EMSQ
Sbjct: 298 Q----ELNTISSAPPQDHVFKVDNFAALGSIQKQLQEKIYAVEGTQSRASSSFQHEMSQE 353
Query: 353 GFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGYTV 412
GFS + D + LGAVG++ W+G + + + TF S + + SYLGY+
Sbjct: 354 GFSTALTMDGLFLGAVGSFSWSGGAFLYPPNM-----SPTFINMSQENVDMRDSYLGYST 408
Query: 413 NSATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDID 472
A L + G PRY HTG+ +I+ + ++G QIGSYFG+ L + D+D
Sbjct: 409 ELALWKGVQNL-VLGAPRYQHTGKAVIFTQVSRQWRKKAEVTGTQIGSYFGASLCSVDVD 467
Query: 473 KDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTT 532
D +TD++L+GAP Y QTR Q+S+ P+ + Q ++
Sbjct: 468 SDGSTDLILIGAPHY---------------YEQTR-GGQVSVCPLPRGQRVQWQCDAVLR 511
Query: 533 ENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKT-IRKEYAQ 591
+ P G RFG A+ + D+N D D+ IGAP E ++ GAVY++HG+ ++ I ++Q
Sbjct: 512 GEQGHPWG-RFGAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQ 570
Query: 592 RIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPN 651
RI S L++FGQ++ G DL DGL D+ +G G L S V V V M F P
Sbjct: 571 RIASSQLSPRLQYFGQALSGGQDLTQDGLMDLAVGARGQVLLLRSLPVLKVGVAMRFSPV 630
Query: 652 KVNIQKKNCHMEGKETV-CINATVCFEVKLKSKEDTI--YEADLQYRVTLDSLRQISRSF 708
+V C E + +ATVC ++ KS D + ++ +++ + LD R SR+
Sbjct: 631 EVAKAVYRCWEEKPSALEAGDATVCLTIQ-KSSLDQLGDIQSSVRFDLALDPGRLTSRAI 689
Query: 709 FSGTQERKVQRNITVRKS-ECTKHSFYMLD-KHDFQDSVRITLDFNLT-----DPEN-GP 760
F+ T+ + R T+ C + D D + + L+F+L P+N P
Sbjct: 690 FNETKNPTLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQNLRP 749
Query: 761 VLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNT 820
VL + +PF K+CG C DL + ++ + L V S + NV +TV N
Sbjct: 750 VLAVGSQDLFTASLPFEKNCGQDGLCEGDLGVTLSFSGLQTLTVGSSLE-LNVIVTVWNA 808
Query: 821 KDSAYNTRTIVHYSPNLVFSGIEAIQKD--------SCES-------NHNITCKVGYPFL 865
+ +Y T ++Y L + QK +CE+ + C V +P
Sbjct: 809 GEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVNHPIF 868
Query: 866 RRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFY 925
G TF + F + + + + + A++ SE + S + +PVKY V
Sbjct: 869 HEGSNGTFIVTFDVSYKATLGD-RMLMRASASSENNKASSSKATFQLELPVKYAV----- 922
Query: 926 SSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISF-PNMTSN 984
+ I+ E + N ++ + + +L +SI+F + N
Sbjct: 923 ------YTMISRQEESTKYFNFATSDEKKMKEAEHRYRVNNLSQRDLAISINFWVPVLLN 976
Query: 985 GYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFATITC 1044
G V + S++ C S + + + R +LDC+ C
Sbjct: 977 GVAVWDVVMEAPSQSLPC--------VSERKPPQHSDFLTQISRSPMLDCSIADCLQFRC 1028
Query: 1045 NLTSSDISQV-------NVSLILWKPTFIKSYF--SSLNLTIRGELRSENASLVLSSSNQ 1095
++ S + + N+S + T K S +T + S+ L +
Sbjct: 1029 DVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTSVYSQ---LPGQEAFM 1085
Query: 1096 KRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKME 1150
+ ++ + + +D + +P +I +K+GFFKR K+ +E
Sbjct: 1086 RAQMEMVLEEDEVYNAIP--IIMGSSVGALLLLALITATLYKLGFFKRHYKEMLE 1138
>gb|AAD25885.1|AF065902_1 (AF065902) integrin alpha L [Mus musculus]
Length = 1161
Score = 339 bits (861), Expect = 8e-92
Identities = 322/1190 (27%), Positives = 518/1190 (43%), Gaps = 131/1190 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
+N+D + + +F FGY V Q E+ V++G+P G + TG +Y C R
Sbjct: 24 YNLDTRPTQSFLAQAGRHFGYQVLQIEDG----VVVGAPGEG---DNTGGLYHC---RTS 73
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNP-NGGFLACGPLYAYRCGHLHYTTGI 119
S C PV+ N T + G TL T+ G LAC P + C Y +G+
Sbjct: 74 SEFCQ----PVSLHGSNHT----SKYLGMTLATDAAKGSLLACDPGLSRTCDQNTYLSGL 125
Query: 120 CSDVSPTFQ--VVNSIAPVQECST-QLDIVIVLDGSNSI--YPWDSVTAFLNDLLKRMDI 174
C + + ++ + QEC ++D+V + DGS S+ ++ + F+ D+++++
Sbjct: 126 CYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVMRKLS- 184
Query: 175 GPKQTQVGIVQYGENVTHEFNLNKY---SSTEEVLVAAKKIVQRGGRQTMTALGTDTARK 231
Q VQ+ + EF Y + +VL+ + VQ T T +
Sbjct: 185 -NTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGS---VQPMFLLTNTFRAINYVVA 240
Query: 232 EAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLS 291
F E GAR KV+VI+TDGE+ D + +I R+ I I + +S
Sbjct: 241 HVFKEESGARPDATKVLVIITDGEASDKGNISAA------HDITRYIIGI----GKHFVS 290
Query: 292 TEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEMS 350
+K + + ASEP E+ F + D L + L RI+A+E T Q SF ME+S
Sbjct: 291 VQK-QKTLHIFASEPVEE-FVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELS 348
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
+G SA S+ ++GAVGA DW G + + + TF + ++ YLGY
Sbjct: 349 SSGISADLSKGHAVVGAVGAKDWAGGFLDLREDL----QGATFVGQEPLTSDVRGGYLGY 404
Query: 411 TVNSATASSGDVLYIAGQPRYNHTGQVIIYRMED--GNIKILQTLSGEQIGSYFGSILTT 468
TV T+ S L AG PRY H GQV++++ + G Q + G QIGSYFG L +
Sbjct: 405 TVAWMTSRSSRPLLAAGAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCS 464
Query: 469 TDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHN 528
D+D+D ++LL+GAP++ G ++ G+V+ Y Q+ FE L+
Sbjct: 465 VDLDQDGEAELLLIGAPLFFGEQRG--GRVFTYQRRQSLFEMVSELQG------------ 510
Query: 529 SCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKE 588
+ P G RFG AI A+ D+N D D+ +GAPLE+ GAVYI++G + +
Sbjct: 511 -----DPGYPLG-RFGAAITALTDINGDRLTDVAVGAPLEEQ--GAVYIFNGKPGGLSPQ 562
Query: 589 YAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNF 648
+QRI +++FG+SIHG DL GD L DV +G G + SR V V ++F
Sbjct: 563 PSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVGPEGRVVVLSSRPVVDVVTELSF 622
Query: 649 EPNKVNIQKKNCHMEGKETV--CINATVCFEVK-LKSKEDTIYEADLQYRVTLDSLRQIS 705
P ++ + + C +E + CF +K L + A+L Y + LD R S
Sbjct: 623 SPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQFQGRLLANLSYTLQLDGHRMRS 682
Query: 706 RSFF-SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGP---- 760
R F G+ E +IT KS H + + D + ++L+F+L + E P
Sbjct: 683 RGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLISPINVSLNFSLLEEEGTPRDQK 742
Query: 761 --VLDDSLPNSVH---EYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSL 815
+ L S+H + IPF K+CG +KC ++L+L L ++ S + V
Sbjct: 743 GRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLSSPARSGPLRLMSSAS--LAVEW 800
Query: 816 TVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNITCKVGY 862
T+ N+ + AY R + + L F +E +Q SCE + C V
Sbjct: 801 TLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSCEELTEGSSLLTKTLKCNVSS 860
Query: 863 PFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETL-SDNVVNISIPVKYEVG 921
P + G+ V+ +++F + E+ + L+ T E +L DN IPV Y V
Sbjct: 861 PIFKAGQEVSLQVMFNTLLNSSWEDF-VELNGTVHCENENSSLQEDNSAATHIPVLYPVN 919
Query: 922 -LQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPN 980
L S +IS + + + + + + + P E + + +P+
Sbjct: 920 ILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAY-----DHNMPTLEALVGVPWPH 974
Query: 981 MTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFA 1040
P+ Y + + C + P S ++ + +
Sbjct: 975 SED---PITYTWSVQTDPLVTCHSEDLKRPSS--EAEQPCLPGVQFRCPIVFRREILIQV 1029
Query: 1041 TITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELA 1100
T T L+ + +SL + S+ SS + + G SE LV ++E+
Sbjct: 1030 TGTVELSKEIKASSTLSLC---SSLSVSFNSSKHFHLYGSKASEAQVLVKVDLIHEKEML 1086
Query: 1101 IQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKME 1150
G+ G V L++I +K+GFFKR LK+KME
Sbjct: 1087 HVYVLSGIGGLVLLFLI--------------FLALYKVGFFKRNLKEKME 1122
>ref|NP_067309.1| integrin alpha X (Cd11c); integrin aX; CD11C (p150) alpha
polypeptide [Mus musculus]
gb|AAF23492.1|AF211864_1 (AF211864) leukocyte adhesion glycoprotein p150,95 alpha integrin
subunit [Mus musculus]
Length = 1169
Score = 339 bits (860), Expect = 1e-91
Identities = 326/1216 (26%), Positives = 535/1216 (43%), Gaps = 148/1216 (12%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
FN+D + F + FG++V QY++ WV++G+P + N+ G +YKC G
Sbjct: 20 FNLDAEKLTHFHMDGAE-FGHSVLQYDSS---WVVVGAPKEIKATNQIGGLYKCGYHTGN 75
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNPNGGFLACGPLYAYRCGHLHYTTGIC 120
P + L +P P + ++ + TNP+ LACGP + C Y TG+C
Sbjct: 76 CEP-ISLQVP-----PEAVNISLGLSLAAA--TNPSW-LLACGPTVHHTCRENIYLTGLC 126
Query: 121 SDVSPTF-QVVNSIAPVQECSTQ-LDIVIVLDGSNSIYPWD--SVTAFLNDLLKRMDIGP 176
+S +F Q N QEC Q DIV ++DGS SI D + F+ ++ ++
Sbjct: 127 FLLSSSFKQSQNFPTAQQECPKQDQDIVFLIDGSGSISSTDFEKMLDFVKAVMSQLQ--R 184
Query: 177 KQTQVGIVQYGENVTHEFNLNKYSSTEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTE 236
T+ ++Q+ + F N + ST L + Q G T TA E FT
Sbjct: 185 PSTRFSLMQFSDYFRVHFTFNNFISTSSPLSLLGSVRQLRG-YTYTASAIKHVITELFTT 243
Query: 237 ARGARRGVKKVMVIVTDGESH-DNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKF 295
GAR+ KV++++TDG DN VI E +I R++I + ++ E
Sbjct: 244 QSGARQDATKVLIVITDGRKQGDNLSYDSVIPMAEAASIIRYAIGVGKAFYN-----EHS 298
Query: 296 VEEIKSIASEPTEKHFFNVSDELALVTIVKTLGERIFALEATADQSAASFEMEMSQTGFS 355
+E+K+IAS P+ ++ F+V + AL I L E+IFA+E T S+++FE+EMSQ GFS
Sbjct: 299 KQELKAIASMPSHEYVFSVENFDALKDIENQLKEKIFAIEGTETPSSSTFELEMSQEGFS 358
Query: 356 AHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLA-SYLGYTVNS 414
A ++ D +LGAVG++ W+G + ++ R T N+ +++NE + +YLGY+
Sbjct: 359 AVFTPDGPVLGAVGSFSWSGGAFLYPSNM----RPTFINM--SQENEDMRDAYLGYSTAL 412
Query: 415 ATASSGDVLYIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKD 474
A L I G PR+ HTG+V+I+ E + + + G QIGSYFG+ L + D+D+D
Sbjct: 413 AFWKGVHSL-ILGAPRHQHTGKVVIFTQESRHWRPKSEVRGTQIGSYFGASLCSVDMDRD 471
Query: 475 SNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTEN 534
+TD++L+G P Y E G+V V + SR H T
Sbjct: 472 GSTDLVLIGVPHYY--EHTRGGQVSVCPMPGV----------------GSRWHCGTTLHG 513
Query: 535 KNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHG-SGKTIRKEYAQRI 593
+ RFG A+ + D+N D D+ IGAP E+++ GAVYI+HG S + I +QRI
Sbjct: 514 EQGHPWGRFGAALTVLGDVNGDSLADVAIGAPGEEENRGAVYIFHGASRQDIAPSPSQRI 573
Query: 594 PSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKV 653
+ +++FGQS+ G DL DGL D+ +G G L +R + V T++F P ++
Sbjct: 574 SASQIPSRIQYFGQSLSGGQDLTRDGLVDLAVGSKGRVLLLRTRPILRVSPTVHFTPAEI 633
Query: 654 NIQKKNCHME-GKETVCINATVCFEVKLKSKEDTIYEADLQYRVT----LDSLRQISRSF 708
+ C + E +ATVC + K DL+ VT LD R +R+
Sbjct: 634 SRSVFECQEQVAPEQTLSDATVCLHIHESPKTQL---GDLRSTVTFDLALDHGRLSTRAI 690
Query: 709 FSGTQERKVQRNITVRKSECTKH--SFYMLDKHDFQDSVR-ITLDFN-------LTDPEN 758
F T+ R + R V+ KH S +L +DSV ITL N ++ +N
Sbjct: 691 FKETKTRALTR---VKTLGLNKHCESVKLLLPACVEDSVTPITLRLNFSLVGVPISSLQN 747
Query: 759 -GPVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTV 817
P+L +PF K+CG C DLS+ + L+V S + NV +TV
Sbjct: 748 LQPMLAVDDQTYFTASLPFEKNCGADHICQDDLSVVFGFPDLKTLVVGSDLE-LNVDVTV 806
Query: 818 KNTKDSAYNTRTIVHYSPNLVFSGIEAIQ--------------------------KDSCE 851
N + +Y T + Y L F + Q D +
Sbjct: 807 SNDGEDSYGTTVTLFYPVGLSFRRVAEGQVFLRKKEDQQWQRRGQHSLHLMCDSTPDRSQ 866
Query: 852 SNHNITCKVGYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVN 911
+ +C + R G +TF + F + + + + L A SE
Sbjct: 867 GLWSTSCSSRHVIFRGGSQMTFLVTFDVSPKAELGD-RLLLRARVGSENNVPGTPKTTFQ 925
Query: 912 ISIPVKYEVGLQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPE 971
+ +PVKY V + I++++ + +N + + ++ + + +
Sbjct: 926 LELPVKYAV-----------YTMISSHDQFTKYLNFSTSEKEKTSVVEHRFQVNNLGQRD 974
Query: 972 LKLSISFPNMTSNGYPVLYPTGLSSSEN--ANC-RPHIFEDPFSINSGKKMTTSTDHLKR 1028
+ +SI+F ++ +S +N C R + F + H+++
Sbjct: 975 VPVSINFWVPIELKGEAVWTVMVSHPQNPLTQCYRNRLKPTQFDL---------LTHMQK 1025
Query: 1029 GTILDCNTCKFATITCNLTS------------SDISQVNVSLILWKPTFIKSYFS-SLNL 1075
+LDC+ + C++ S ++S +S L K + S + N
Sbjct: 1026 SPVLDCSIADCLHLRCDIPSLGILDELYFILKGNLSFGWISQTLQKKVLLLSEAEITFNT 1085
Query: 1076 TIRGELRSENASLVLSSSNQKRELAIQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXX 1135
++ +L + A L + + +++ K P VPL I
Sbjct: 1086 SVYSQLPGQEAFL-----RAQTKTVLEMYKVHNP--VPL--IVGSSVGGLLLLAIITAIL 1136
Query: 1136 WKIGFFKRPLKKKMEK 1151
+K GFFKR K+ +E+
Sbjct: 1137 YKAGFFKRQYKEMLEE 1152
>sp|P24063|ITAL_MOUSE LEUKOCYTE ADHESION GLYCOPROTEIN LFA-1 ALPHA CHAIN PRECURSOR
(LEUKOCYTE FUNCTION ASSOCIATED MOLECULE 1, ALPHA CHAIN)
(INTEGRIN ALPHA-L)
pir||I56126 lymphocyte fuction-associated molecule-1-alpha - mouse
gb|AAA39426.1| (M60778) lymphocyte fuction-associated molecule-1-alpha [Mus
musculus]
Length = 1163
Score = 339 bits (860), Expect = 1e-91
Identities = 323/1190 (27%), Positives = 516/1190 (43%), Gaps = 131/1190 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
+N+D + + +F FGY V Q E+ V++G+P G + TG +Y C R
Sbjct: 24 YNLDTRPTQSFLAQAGRHFGYQVLQIEDG----VVVGAPGEG---DNTGGLYHC---RTS 73
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNP-NGGFLACGPLYAYRCGHLHYTTGI 119
S C PV+ N T + G TL T+ G LAC P + C Y +G+
Sbjct: 74 SEFCQ----PVSLHGSNHT----SKYLGMTLATDAAKGSLLACDPGLSRTCDQNTYLSGL 125
Query: 120 CSDVSPTFQ--VVNSIAPVQECST-QLDIVIVLDGSNSI--YPWDSVTAFLNDLLKRMDI 174
C + + ++ + QEC ++D+V + DGS S+ ++ + F+ D+++++
Sbjct: 126 CYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVMRKLS- 184
Query: 175 GPKQTQVGIVQYGENVTHEFNLNKY---SSTEEVLVAAKKIVQRGGRQTMTALGTDTARK 231
Q VQ+ + EF Y + +VL+ + VQ T T +
Sbjct: 185 -NTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGS---VQPMFLLTNTFRAINYVVA 240
Query: 232 EAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLS 291
F E GAR KV+VI+TDGE+ D + +I R+ I I + +S
Sbjct: 241 HVFKEESGARPDATKVLVIITDGEASDKGNISAA------HDITRYIIGI----GKHFVS 290
Query: 292 TEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEMS 350
+K + + ASEP E+ F + D L + L RI+A+E T Q SF ME+S
Sbjct: 291 VQK-QKTLHIFASEPVEE-FVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELS 348
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
+G SA S+ ++GAVGA DW G + + + TF + ++ YLGY
Sbjct: 349 SSGISADLSKGHAVVGAVGAKDWAGGFLDLREDL----QGATFVGQEPLTSDVRGGYLGY 404
Query: 411 TVNSATASSGDVLYIAGQPRYNHTGQVIIYRMED--GNIKILQTLSGEQIGSYFGSILTT 468
TV T+ S L AG PRY H GQV++++ + G Q + G QIGSYFG L +
Sbjct: 405 TVAWMTSRSSRPLLAAGAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCS 464
Query: 469 TDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHN 528
D+D+D ++LL+GAP++ G ++ G+V+ Y Q+ FE L+
Sbjct: 465 VDLDQDGEAELLLIGAPLFFGEQRG--GRVFTYQRRQSLFEMVSELQG------------ 510
Query: 529 SCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKE 588
+ P G RFG AI A+ D+N D D+ +GAPLE+ GAVYI++G + +
Sbjct: 511 -----DPGYPLG-RFGAAITALTDINGDRLTDVAVGAPLEEQ--GAVYIFNGKPGGLSPQ 562
Query: 589 YAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNF 648
+QRI +++FG+SIHG DL GD L DV +G G + SR V V ++F
Sbjct: 563 PSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVGAEGRVVVLSSRPVVDVVTELSF 622
Query: 649 EPNKVNIQKKNCHMEGKETV--CINATVCFEVK-LKSKEDTIYEADLQYRVTLDSLRQIS 705
P ++ + + C +E + CF +K L + A+L Y + LD R S
Sbjct: 623 SPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQFQGRLLANLSYTLQLDGHRMRS 682
Query: 706 RSFF-SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGP---- 760
R F G+ E +IT KS H + + D + ++L+F+L + E P
Sbjct: 683 RGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLISPINVSLNFSLLEEEGTPRDQK 742
Query: 761 --VLDDSLPNSVH---EYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSL 815
+ L S+H + IPF K+CG +KC ++L+L L ++ S + V
Sbjct: 743 GRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLSSPARSGPLRLMSSAS--LAVEW 800
Query: 816 TVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNITCKVGY 862
T+ N+ + AY R + + L F +E +Q SCE + C V
Sbjct: 801 TLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSCEELTEGSSLLTKTLKCNVSS 860
Query: 863 PFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETL-SDNVVNISIPVKYEVG 921
P + G+ V+ +++F + E+ + L+ T E +L DN IPV Y V
Sbjct: 861 PIFKAGQEVSLQVMFNTLLNSSWEDF-VELNGTVHCENENSSLQEDNSAATHIPVLYPVN 919
Query: 922 -LQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPN 980
L S +IS + + + + + + MP L+ + P
Sbjct: 920 ILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAY-------DHNMPTLEALVGVPR 972
Query: 981 MTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFA 1040
S + Y + + C + P S ++ + +
Sbjct: 973 PHSEDL-ITYTWSVQTDPLVTCHSEDLKRPSS--EAEQPCLPGVQFRCPIVFRWEILIQV 1029
Query: 1041 TITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELA 1100
T T L+ + +SL + S+ SS + + G SE LV ++E+
Sbjct: 1030 TGTVELSKEIKASSTLSLC---SSLSVSFNSSKHFHLYGSKASEAQVLVKVDLIHEKEML 1086
Query: 1101 IQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKME 1150
G+ G V L++I +K+GFFKR LK+KME
Sbjct: 1087 HVYVLSGIGGLVLLFLI--------------FLALYKVGFFKRNLKEKME 1122
>gb|AAD25884.1|AF065901_1 (AF065901) integrin alpha L [Mus musculus]
Length = 1160
Score = 335 bits (851), Expect = 1e-90
Identities = 322/1190 (27%), Positives = 516/1190 (43%), Gaps = 132/1190 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRTGDVYKCPVGRGE 60
+N+D + + +F FGY V Q E+ V++G+P G + TG +Y C R
Sbjct: 24 YNLDTRPTQSFLAQAGRHFGYQVLQIEDG----VVVGAPGEG---DNTGGLYHC---RTS 73
Query: 61 SLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVTNP-NGGFLACGPLYAYRCGHLHYTTGI 119
S C PV+ N T + G TL T+ G LAC P + C Y +G+
Sbjct: 74 SEFCQ----PVSLHGSNHT----SKYLGMTLATDAAKGSLLACDPGLSRTCDQNTYLSGL 125
Query: 120 CSDVSPTFQ--VVNSIAPVQECST-QLDIVIVLDGSNSI--YPWDSVTAFLNDLLKRMDI 174
C + + ++ + QEC ++D+V + DGS S+ ++ + F+ D+++++
Sbjct: 126 CYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVMRKLS- 184
Query: 175 GPKQTQVGIVQYGENVTHEFNLNKY---SSTEEVLVAAKKIVQRGGRQTMTALGTDTARK 231
Q VQ+ + EF Y + +VL+ + VQ T T +
Sbjct: 185 -NTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGS---VQPMFLLTNTFRAINYVVA 240
Query: 232 EAFTEARGARRGVKKVMVIVTDGESHDNHRLKKVIQDCEDENIQRFSIAILGSYNRGNLS 291
F E GAR KV+VI+TDGE+ D + +I R+ I I + +S
Sbjct: 241 HVFKEESGARPDATKVLVIITDGEASDKGNISAA------HDITRYIIGI----GKHFVS 290
Query: 292 TEKFVEEIKSIASEPTEKHFFNVSDELA-LVTIVKTLGERIFALEATADQSAASFEMEMS 350
+K + + ASEP E+ F + D L + L RI+A+E T Q SF ME+S
Sbjct: 291 VQK-QKTLHIFASEPVEE-FVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELS 348
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
+G SA S+ ++GAVGA DW G + + + TF + ++ YLGY
Sbjct: 349 SSGISADLSKGHAVVGAVGAKDWAGGFLDLREDL----QGATFVGQEPLTSDVRGGYLGY 404
Query: 411 TVNSATASSGDVLYIAGQPRYNHTGQVIIYRMED--GNIKILQTLSGEQIGSYFGSILTT 468
TV T+ S L AG PRY H GQV++++ + G Q + G QIGSYFG L +
Sbjct: 405 TVAWMTSRSSRPLLAAGAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCS 464
Query: 469 TDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHN 528
D+D+D ++LL+GAP++ G ++ G+V+ Y Q+ FE L+
Sbjct: 465 VDLDQDGEAELLLIGAPLFFGEQRG--GRVFTYQRRQSLFEMVSELQG------------ 510
Query: 529 SCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKE 588
+ P G RFG AI A+ D+N D D+ +GAPLE+ GAVYI++G + +
Sbjct: 511 -----DPGYPLG-RFGAAITALTDINGDRLTDVAVGAPLEEQ--GAVYIFNGKPGGLSPQ 562
Query: 589 YAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNF 648
+QRI +++FG+SIHG DL GD L +V +G G + SR V V ++F
Sbjct: 563 PSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLANVVVGPEGRVVVLSSRPVVDVVTELSF 622
Query: 649 EPNKVNIQKKNCHMEGKETV--CINATVCFEVK-LKSKEDTIYEADLQYRVTLDSLRQIS 705
P ++ + + C +E + CF +K L + A+L Y + LD R S
Sbjct: 623 SPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQFQGRLLANLSYTLQLDGHRMRS 682
Query: 706 RSFF-SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPENGP---- 760
R F G+ E +IT KS H + + D + ++L+F+L + E P
Sbjct: 683 RGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLISPINVSLNFSLLEEEGTPRDQK 742
Query: 761 --VLDDSLPNSVH---EYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSL 815
+ L S+H + IPF K+CG +KC ++L+L L ++ S + V
Sbjct: 743 GRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTLSSPARSGPLRLMSSAS--LAVEW 800
Query: 816 TVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD-----SCES--------NHNITCKVGY 862
T+ N+ + AY R + + L F +E +Q SCE + C V
Sbjct: 801 TLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVSCEELTEGSSLLTKTLKCNVSS 860
Query: 863 PFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETL-SDNVVNISIPVKYEVG 921
P + G+ V+ +++F + E+ + L+ T E +L DN IPV Y V
Sbjct: 861 PIFKAGQEVSLQVMFNTLLNSSWEDF-VELNGTVHCENENSSLQEDNSAATHIPVLYPVN 919
Query: 922 -LQFYSSASEYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLSISFPN 980
L S +IS + + + + + + MP L+ + P
Sbjct: 920 ILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAY-------DHNMPTLEALVGVPR 972
Query: 981 MTSNGYPVLYPTGLSSSENANCRPHIFEDPFSINSGKKMTTSTDHLKRGTILDCNTCKFA 1040
S + Y + + C + P +S + + +
Sbjct: 973 PHSEDL-ITYTWSVQTDPLVTCHSEDLKRP---SSEAEPCLPGVQFRCPIVFRWEILIQV 1028
Query: 1041 TITCNLTSSDISQVNVSLILWKPTFIKSYFSSLNLTIRGELRSENASLVLSSSNQKRELA 1100
T T L+ + +SL + S+ SS + + G SE LV ++E+
Sbjct: 1029 TGTVELSKEIKASSTLSLC---SSLSVSFNSSKHFHLYGSKASEAQVLVKVDLIHEKEML 1085
Query: 1101 IQISKDGLPGRVPLWVIXXXXXXXXXXXXXXXXXXWKIGFFKRPLKKKME 1150
G+ G V L++I +K+GFFKR LK+KME
Sbjct: 1086 HVYVLSGIGGLVLLFLI--------------FLALYKVGFFKRNLKEKME 1121
>gb|AAB16869.1| (U40072) CD11b [Sus scrofa]
Length = 920
Score = 333 bits (844), Expect = 8e-90
Identities = 253/846 (29%), Positives = 399/846 (46%), Gaps = 72/846 (8%)
Query: 144 DIVIVLDGSNSIYPWD--SVTAFLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
DI ++DGS SI D + F++ ++ + +T ++QY E+ F N +
Sbjct: 17 DIAFLIDGSGSINRLDFQRMKEFVSTVMGQFQ--KSKTLFALMQYSEDFYTHFTFNDFKR 74
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNH 260
+ + I Q GR T TA G +E F GAR K++V++TDGE D
Sbjct: 75 NPSPKLLVRPIRQLLGR-THTATGIRKVVRELFHSKSGARENALKILVVITDGEKFGDPL 133
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
+ VI + + + + R+ I + ++N + K EE+ +IAS+P H F V++ A+
Sbjct: 134 GYEDVIPEADRKGVIRYVIGVGDAFN-----SWKSREELNTIASKPCGDHVFQVNNFEAV 188
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQDWVMLGAVGAYDWNGTVVMQ 380
TI L E+ FA+E T S +SFE EMSQ GFSA + + +LGAVG++DW G +
Sbjct: 189 KTIQNQLQEKTFAIEGTQTGSTSSFECEMSQEGFSAAITSNGPLLGAVGSFDWAGGAFLH 248
Query: 381 KASQIIIPRNTTFNVESTKKNEPLASYLGYTVNSATASSGDVLYIAGQPRYNHTGQVIIY 440
+I NTT V+S + +YLGY V + L + G PRY HTG V+++
Sbjct: 249 MPKDRVIFINTT-RVDSDMND----AYLGYAVEVILRNQAQSL-VLGAPRYQHTGLVVMF 302
Query: 441 RMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYV 500
+ G + + G QIGSYFG+ L + D+++D ++D++L+GAP Y E+ G+V V
Sbjct: 303 KQNSGAWEKNADIKGSQIGSYFGASLCSVDVNRDGSSDLVLIGAPHYY--EQTRGGQVSV 360
Query: 501 YALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFND 560
L Q R ++Q + C + H +RFG A+ A+ D+N D D
Sbjct: 361 CPLPQGRAKWQ-----CRVILCGEQGHP-----------WSRFGAALTALGDVNGDKLTD 404
Query: 561 IVIGAPLEDDHGGAVYIYHGSGKT-IRKEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDG 619
+ IGAP E D+ GAVY++HG+ + I ++QRI L++FGQS+ G DL DG
Sbjct: 405 VAIGAPGEQDNRGAVYLFHGTSELGISPSHSQRIAGSQLSPRLQYFGQSLSGGQDLTMDG 464
Query: 620 LTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKET-VCINATVCFEV 678
L D+ +G G L S+ V V+ +M F+P +V C + +T + VC +V
Sbjct: 465 LMDLAVGAQGHVFLLRSQPVLRVEASMVFKPREVARNVYECRQQAAKTQIAGEVQVCLQV 524
Query: 679 KLKSKEDTIYEADLQ----YRVTLDSLRQISRSFFSGTQERKVQRNITVRKSECTKHSFY 734
+ KS D + E D Q Y + LD R R+ F T+ ++ T+ S +H
Sbjct: 525 R-KSTWDRLREGDTQSIITYDLALDPGRPHPRAVFEETKNNTRRQTQTLGLSRKCEHLAL 583
Query: 735 MLDK--HDFQDSVRITLDFNLTDPENG------PVLDDSLPNSVHEYIPFAKDCGNKEKC 786
L D + + L+F+L PVL PF K+CGN C
Sbjct: 584 WLPDCVEDSVTPIVLRLNFSLVGKPASSFGNLRPVLAVDAQRLFTALFPFEKNCGNDSIC 643
Query: 787 ISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQ 846
DLS+ + D L+V D V+LTV+N + +Y T+ Y +L + + Q
Sbjct: 644 QDDLSITFSFMSLDTLVVGGPRD-LKVTLTVRNQGEDSYRTQVTFFYPSDLSYRKVSTSQ 702
Query: 847 KD--------SCESN---------HNITCKVGYPFLRRGEMVTFKILFQFN-TSYLMENV 888
+CES+ + +C + +P VTF + F N ++L +
Sbjct: 703 NQRSQRSWRLACESDVSTEESTALKSTSCSINHPIFPDNSEVTFNVTFDVNPDAFLGYKL 762
Query: 889 TIYLSATSDSEEPPETLSDNVVNISIPVKYEVGLQFYS-SASEYHISIAANETVPEVINS 947
+ + TS++ P ++ + +PVKY V + S S + + A+E VI
Sbjct: 763 LLKANVTSENNMPSSNKTE--FQLELPVKYAVYVVVTSLEVSTKYFNFTASEKTRHVIEH 820
Query: 948 TEDIGN 953
N
Sbjct: 821 QYQFNN 826
>gb|AAC23662.1| (AF020045) integrin alpha E1 [Rattus norvegicus]
Length = 1167
Score = 290 bits (734), Expect = 6e-77
Identities = 239/801 (29%), Positives = 383/801 (46%), Gaps = 85/801 (10%)
Query: 144 DIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
+I IVLDGS SI P D A F++ +++ + +VQYG + EF+L +
Sbjct: 195 EIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGAVIQTEFDLQESRD 254
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNH 260
L + IVQ T TA F +RG+R+ KVMV++TDG+ D
Sbjct: 255 INASLAKVQSIVQVK-EVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFGDPL 313
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
L VI + + + RF+I + ++ N E+K IAS+P E H F V++ AL
Sbjct: 314 NLTTVINSPKMQGVVRFAIGVGDAFKNNNT-----YRELKLIASDPKEAHTFKVTNYSAL 368
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY-SQDWVMLGAVGAYDWNGTVVM 379
++ L +RI +E T + + +++QTGFSA + V+LG VGA++W+G ++
Sbjct: 369 DGLLSKLQQRIVHMEGTVGDA---LQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALL 425
Query: 380 QKASQIIIPRNTTFNVESTKKNEPLA-SYLGYTVNSATASSGDVLYIAGQPRYNHTGQVI 438
R N + + + + SYLGY++ + G + Y+AG PR+ G V
Sbjct: 426 YSTQN---GRGCFLNQTAKEDSRTVQYSYLGYSLAVLHKAHG-ISYVAGAPRHKLRGAVF 481
Query: 439 IYRMEDGNIK-ILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGK 497
R ED ++ + GEQ+GSYFGS+L DID D TD LLV AP Y + E+G+
Sbjct: 482 ELRKEDREEDAFVRRIEGEQMGSYFGSVLCPVDIDMDGTTDFLLVAAPFYH--IRGEEGR 539
Query: 498 VYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDG 557
VYVY + + Q S H T +RFG A+AAV D+N D
Sbjct: 540 VYVYQVPE-------------QDASFSLAH---TLSGHPGLTNSRFGFAMAAVGDINQDK 583
Query: 558 FNDIVIGAPLEDDHGG------AVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHG 611
F D+ IGAPLE G +VYIY+G + +Q+I + L +FG S+ G
Sbjct: 584 FTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLYDSPSQQIRASSVASGLHYFGMSVSG 643
Query: 612 EMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCIN 671
+D NGDGL D+T+G A + SR V + V+M F P+ + + GK ++
Sbjct: 644 GLDFNGDGLADITVGSRDSAVVLRSRPVVDLTVSMTFTPDALPMV-----FIGK----MD 694
Query: 672 ATVCFEV--KLKSKEDTIYEADLQYRVTLDSLRQISR---SFFSGTQERKVQRNITVRKS 726
+CFEV + + E + E L + V +D +Q R SG Q + N S
Sbjct: 695 VNLCFEVDSSVVASEPGLREMFLNFTVDVDVTKQRQRLQCEDSSGCQSCLRKWN---GGS 751
Query: 727 ECTKHSFYMLDKHDFQD-------SVRITLDFNLTDPEN---GPVLDDSLPNSVHEYIPF 776
+H F+++ + + ++++T +F + P LD S +P+
Sbjct: 752 FLCEH-FWLISTEELCEEDCFSNITIKVTYEFQTSGGRRDYPNPTLDHYKEPSAIFQLPY 810
Query: 777 AKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPN 836
KDC NK CI+++ L ++++L++ ++ N+SLT N+ + +Y T ++Y N
Sbjct: 811 EKDCKNKVFCIAEIQLTTNISQQELVVGVTKEVTMNISLT--NSGEDSYMTNMALNYPRN 868
Query: 837 LVFSGIEA-----IQKDSCESNHNI---TCKVGYPFLRRGEMVTFKILFQFNTSYL---M 885
L F I+ +Q D + ++ CK+G+P L+R V + +Q S
Sbjct: 869 LQFKKIQKPVSPDVQCDDPKPVASVLVMNCKIGHPILKRSS-VNVSVTWQLEESVFPNRT 927
Query: 886 ENVTIYLSATSDSEEPPETLS 906
++T+ +S +++ ET S
Sbjct: 928 ADITVTISNSNEKSLARETRS 948
>ref|NP_032425.1| integrin, alpha E, epithelial-associated [Mus musculus]
sp|Q60677|ITAE_MOUSE INTEGRIN ALPHA-E PRECURSOR (INTEGRIN ALPHA M290)
gb|AAC52142.1| (U12236) alpha M290 integrin [Mus musculus]
Length = 1167
Score = 289 bits (731), Expect = 1e-76
Identities = 239/801 (29%), Positives = 382/801 (46%), Gaps = 85/801 (10%)
Query: 144 DIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
+I IVLDGS SI P D A F++ +++ + +VQYG + EF+L +
Sbjct: 195 EIAIVLDGSGSIGPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGAVIQTEFDLQESRD 254
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNH 260
L + IVQ T TA F +RG+R+ KVMV++TDG+ D
Sbjct: 255 INASLAKVQSIVQVK-EVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFGDPL 313
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
L VI + + + RF+I + + N E+K IAS+P E H F V++ AL
Sbjct: 314 NLTTVINSPKMQGVVRFAIGVGDRFKNNNT-----YRELKLIASDPKEAHTFKVTNYSAL 368
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY-SQDWVMLGAVGAYDWNGTVVM 379
++ L +RI +E T + + +++QTGFSA + V+LG VGA++W+G ++
Sbjct: 369 DGLLSKLQQRIVHMEGTVGDA---LQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALL 425
Query: 380 QKASQIIIPRNTTFNVESTKKNEPLA-SYLGYTVNSATASSGDVLYIAGQPRYNHTGQVI 438
R N + + + + SYLGY++ + G + Y+AG PR+ G V
Sbjct: 426 YSTQN---GRGCFLNQTAKEDSRTVQYSYLGYSLAVLHKAHG-ISYVAGAPRHKLRGAVF 481
Query: 439 IYRMEDGNIK-ILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGK 497
R ED ++ + GEQ+GSYFGS+L DID D TD LLV AP Y + E+G+
Sbjct: 482 ELRKEDREEDAFVRRIEGEQMGSYFGSVLCPVDIDMDGTTDFLLVAAPFYH--IRGEEGR 539
Query: 498 VYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDG 557
VYVY + + Q S H T +RFG A+AAV D+N D
Sbjct: 540 VYVYQVPE-------------QDASFSLAH---TLSGHPGLTNSRFGFAMAAVGDINQDK 583
Query: 558 FNDIVIGAPLEDDHGG------AVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHG 611
F D+ IGAPLE G +VYIY+G + +Q+I + L +FG S+ G
Sbjct: 584 FTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLYDSPSQQIRASSVASGLHYFGMSVSG 643
Query: 612 EMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCIN 671
+D NGDGL D+T+G A + SR V + V+M F P+ + + GK ++
Sbjct: 644 GLDFNGDGLADITVGSRDSAVVLRSRPVVDLTVSMTFTPDALPMV-----FIGK----MD 694
Query: 672 ATVCFEV--KLKSKEDTIYEADLQYRVTLDSLRQISR---SFFSGTQERKVQRNITVRKS 726
+CFEV + + E + E L + V +D +Q R SG Q + N S
Sbjct: 695 VNLCFEVDSSVVASEPGLREMFLNFTVDVDVTKQRQRLQCEDSSGCQSCLRKWN---GGS 751
Query: 727 ECTKHSFYMLDKHDFQD-------SVRITLDFNLTDPEN---GPVLDDSLPNSVHEYIPF 776
+H F+++ + + ++++T +F + P LD S +P+
Sbjct: 752 FLCEH-FWLISTEELCEEDCFSNITIKVTYEFQTSGGRRDYPNPTLDHYKEPSAIFQLPY 810
Query: 777 AKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPN 836
KDC NK CI+++ L ++++L++ ++ N+SLT N+ + +Y T ++Y N
Sbjct: 811 EKDCKNKVFCIAEIQLTTNISQQELVVGVTKEVTMNISLT--NSGEDSYMTNMALNYPRN 868
Query: 837 LVFSGIEA-----IQKDSCESNHNI---TCKVGYPFLRRGEMVTFKILFQFNTSYL---M 885
L F I+ +Q D + ++ CK+G+P L+R V + +Q S
Sbjct: 869 LQFKKIQKPVSPDVQCDDPKPVASVLVMNCKIGHPILKRSS-VNVSVTWQLEESVFPNRT 927
Query: 886 ENVTIYLSATSDSEEPPETLS 906
++T+ +S +++ ET S
Sbjct: 928 ADITVTISNSNEKSLARETRS 948
>gb|AAC23663.1| (AF020046) integrin alpha E2 [Rattus norvegicus]
Length = 1167
Score = 288 bits (730), Expect = 2e-76
Identities = 231/801 (28%), Positives = 382/801 (46%), Gaps = 85/801 (10%)
Query: 144 DIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
+I IVLDGS SI P D A F++ +++ + +VQYG + EF+L
Sbjct: 195 EIAIVLDGSGSIEPSDFQKAKDFISTMMRNFYEKCFECNFALVQYGGVIQTEFDLLDSRD 254
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGES-HDNH 260
L + IVQ T TA F +RG+R+ KVMV++TDG+ D
Sbjct: 255 INASLAKVQSIVQVK-EVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFRDPL 313
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
L VI + + + RF+I + ++ N E+K IAS+P H F V++ AL
Sbjct: 314 NLTTVISSSKMQGVVRFAIGVGNAFENNNT-----YRELKLIASDPKAAHTFKVTNYSAL 368
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY-SQDWVMLGAVGAYDWNGTVVM 379
++ L +RI +E T + + +++QTGFSA + V+LG VGA++W+G ++
Sbjct: 369 DGLLSKLQQRIIHMEGTVGDT---LQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALL 425
Query: 380 QKASQIIIPRNTTFNVESTKKNEPLA--SYLGYTVNSATASSGDVLYIAGQPRYNHTGQV 437
F ++ K++ A SYLGY+V + + G V Y+AG PR+ G V
Sbjct: 426 YNTQN----GRGRFLNQTAKEDFRAAQYSYLGYSVAALHKAHG-VSYVAGAPRHKLRGAV 480
Query: 438 IIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGK 497
+ EDG ++ + GEQ+GSYFGS+L DI+ D TD LLV AP Y + E+G+
Sbjct: 481 FELQKEDGEETFMRRIEGEQMGSYFGSVLCPVDINMDGITDFLLVAAPFY--HIRGEEGR 538
Query: 498 VYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDG 557
VYVY +++ + + T +RFG A+AAV D+N D
Sbjct: 539 VYVYRVHEQDAPFSLVY----------------TLSGYPGLTSSRFGFAMAAVGDINQDK 582
Query: 558 FNDIVIGAPLEDDHG------GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHG 611
F D+ IGAPLE G+VYIY+G + +Q+I + L +FG S+ G
Sbjct: 583 FTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLHASPSQQIRASSVALGLYYFGMSVSG 642
Query: 612 EMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCIN 671
+D +GD L D+T+G A + SR V + V+M F P+ + + K+ ++
Sbjct: 643 GLDFSGDDLADITVGSQDVAVVLRSRPVVDLTVSMTFTPDALPMAFKD---------KMD 693
Query: 672 ATVCFEVKLKS--KEDTIYEADLQYRVTLDSLRQISRSFFSGTQERKVQRNITVR----K 725
+CF+V + E + L + V +D +Q R +R ++ ++
Sbjct: 694 VELCFKVDSSAVPSEPGLRGMSLNFTVDVDVTKQKQR---LQCADRSCCQSCLMKWSGGS 750
Query: 726 SECTKHSFYMLDKHDFQD------SVRITLDFNLTDPEN---GPVLDDSLPNSVHEYIPF 776
S C ++ +D +++++ +F ++ P+LD S +P+
Sbjct: 751 SLCEHFGLISTEEELCEDDCFSNITIKVSYEFQTSEERRNHPNPILDHYKEPSAIFQLPY 810
Query: 777 AKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPN 836
KDC NK CI+++ L A +++DL++ ++ N+SLT N+ + +Y T ++Y N
Sbjct: 811 EKDCKNKVFCIAEIQLTTAISQQDLVVGITKEVTMNISLT--NSGEDSYMTNMALNYPRN 868
Query: 837 LVFSGIEA-----IQKDSCESNHNI---TCKVGYPFLRRGEMVTFKILFQFNTSYL---M 885
L F I+ IQ D + ++ CK+G+P L+R V + +Q S
Sbjct: 869 LQFKKIQKPLSPDIQCDDPKPVASVLVMNCKIGHPILKRSS-VNVSVTWQLEESIFPNRT 927
Query: 886 ENVTIYLSATSDSEEPPETLS 906
++T+ +S +++ ET S
Sbjct: 928 ADITVTISNSNEKSLARETHS 948
>gb|AAF43107.1| (AF168787) HUMINAE [Homo sapiens]
Length = 1127
Score = 287 bits (727), Expect = 4e-76
Identities = 232/757 (30%), Positives = 360/757 (46%), Gaps = 75/757 (9%)
Query: 144 DIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
+I I+LDGS SI P D A F++++++ + +VQYG + EF+L
Sbjct: 150 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 209
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGES-HDNH 260
L + I Q G T TA FT + G+RR KVMV++TDG D
Sbjct: 210 VMASLARVQNITQVGS-VTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 268
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
L VI + + ++RF+I + + + + E+ IAS+P E H F V++ +AL
Sbjct: 269 NLTTVINSPKMQGVERFAIGVGEEFK-----SARTARELNLIASDPDETHAFKVTNYMAL 323
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQD-WVMLGAVGAYDWNGTVVM 379
++ L I ++E T + +++Q GFSA + V+LGAVGA+DW+G ++
Sbjct: 324 DGLLSKLRYNIISMEGTVGDA---LHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL 380
Query: 380 QKASQIIIPRNTTFNVESTKKNEPLA---SYLGYTVNSATASSGDVLYIAGQPRYNHTGQ 436
R N + + A SYLGY V + + + YIAG PRY H G
Sbjct: 381 YDTRS---RRGRFLNQTAAAAADAEAAQYSYLGYAV-AVLHKTCSLSYIAGAPRYKHHGA 436
Query: 437 VIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQG 496
V + E L L GEQ+GSYFGS L DID D +TD LLV AP Y E+G
Sbjct: 437 VFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEEG 494
Query: 497 KVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLD 556
+VYVY L++ + SL I H T ARFG A+AA+ DL+ D
Sbjct: 495 RVYVYRLSEQ--DGSFSLARILS------GHPGFT--------NARFGFAMAAMGDLSQD 538
Query: 557 GFNDIVIGAPLED---DHG---GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIH 610
D+ IGAPLE D G G+VYIY+G + +QRI + L++FG S+
Sbjct: 539 KLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMA 598
Query: 611 GEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCI 670
G D++GDGL D+T+G LG A +F SR V +KV+M F P+ + I +
Sbjct: 599 GGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNG---------VV 649
Query: 671 NATVCFEVK--LKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQE-----RKVQRNITV 723
N +CFE+ + E + EA L + + +D +Q R S + R+ +
Sbjct: 650 NVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQL 709
Query: 724 RKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPEN-----GPVLDDSLPNSVHEYIPFAK 778
+ + L + D + + + + L PE P+LD +P+ K
Sbjct: 710 CEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEK 769
Query: 779 DCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLV 838
C NK C+++L L ++++L++ ++ N++LT N+ + +Y T ++Y NL
Sbjct: 770 ACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLT--NSGEDSYMTSMALNYPRNLQ 827
Query: 839 FSGIEA-----IQKDSCESNHNI---TCKVGYPFLRR 867
++ IQ D + ++ C++G+P L+R
Sbjct: 828 LKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKR 864
>gb|AAD30063.1| (AF133085) Itgae protein [Mus sp.]
Length = 895
Score = 286 bits (725), Expect = 7e-76
Identities = 231/759 (30%), Positives = 366/759 (47%), Gaps = 81/759 (10%)
Query: 144 DIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
+I IVLDGS SI P D A F++ +++ + +VQYG + EF+L +
Sbjct: 182 EIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGAVIQTEFDLQESRD 241
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGESH-DNH 260
L + IVQ T TA F +RG+R+ KVMV++TDG+ D
Sbjct: 242 INASLAKVQSIVQVK-EVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFGDPL 300
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
L VI + + + RF+I + ++ N E+K IAS+P E H F V++ AL
Sbjct: 301 NLTTVINSPKMQGVVRFAIGVGDAFKNNNT-----YRELKLIASDPKEAHTFKVTNYSAL 355
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHY-SQDWVMLGAVGAYDWNGTVVM 379
++ L +RI +E T + + +++QTGFSA + V+LG VGA++W+G ++
Sbjct: 356 DGLLSKLQQRIVHMEGTVGDA---LQYQLAQTGFSAQILDKGQVLLGTVGAFNWSGGALL 412
Query: 380 QKASQIIIPRNTTFNVESTKKNEPLA-SYLGYTVNSATASSGDVLYIAGQPRYNHTGQVI 438
R N + + + + SYLGY++ + G + Y+AG PR+ G V
Sbjct: 413 YSTQN---GRGCFLNQTAKEDSRTVQYSYLGYSLAVLHKAHG-ISYVAGAPRHKLRGAVF 468
Query: 439 IYRMEDGNIK-ILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQGK 497
R ED ++ + GEQ+GSYFGS+L DID D TD LLV AP Y + E+G+
Sbjct: 469 ELRKEDREEDAFVRRIEGEQMGSYFGSVLCPVDIDMDGTTDFLLVAAPFYH--IRGEEGR 526
Query: 498 VYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDG 557
VYVY + + Q S H T +RFG A+AAV D+N D
Sbjct: 527 VYVYQVPE-------------QDASFSLAH---TLSGHPGLTNSRFGFAMAAVGDINQDK 570
Query: 558 FNDIVIGAPLEDDHGG------AVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIHG 611
F D+ IGAPLE G +VYIY+G + +Q+I + L +FG S+ G
Sbjct: 571 FTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLYDSPSQQIRASSVASGLHYFGMSVSG 630
Query: 612 EMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCIN 671
+D NGDGL D+T+G A + SR V + V+M F P+ + + GK ++
Sbjct: 631 GLDFNGDGLADITVGSRDSAVVLRSRPVVDLTVSMTFTPDALPMV-----FIGK----MD 681
Query: 672 ATVCFEV--KLKSKEDTIYEADLQYRVTLDSLRQISR---SFFSGTQERKVQRNITVRKS 726
+CFEV + + E + E L + V +D +Q R SG Q + N S
Sbjct: 682 VNLCFEVDSSVVASEPGLREMFLNFTVDVDVTKQRQRLQCEDSSGCQSCLRKWN---GGS 738
Query: 727 ECTKHSFYMLDKHDFQD-------SVRITLDFNLTDPEN---GPVLDDSLPNSVHEYIPF 776
+H F+++ + + ++++T +F + P LD S +P+
Sbjct: 739 FLCEH-FWLISTEELCEEDCFSNITIKVTYEFQTSGGRRDYPNPTLDHYKEPSAIFQLPY 797
Query: 777 AKDCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPN 836
KDC NK CI+++ L ++++L++ ++ N+SLT N+ + +Y T ++Y N
Sbjct: 798 EKDCKNKVFCIAEIQLTTNISQQELVVGVTKEVTMNISLT--NSGEDSYMTNMALNYPRN 855
Query: 837 LVFSGIEA-----IQKDSCESNHNI---TCKVGYPFLRR 867
L F I+ +Q D + ++ CK+G+P L+R
Sbjct: 856 LQFKKIQKPVSPDVQCDDPKPVASVLVMNCKIGHPILKR 894
>ref|NP_002199.2| integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen
1; alpha polypeptide); antigen CD103, human mucosal
lymphocyte antigen 1; alpha polypeptide [Homo sapiens]
sp|P38570|ITAE_HUMAN INTEGRIN ALPHA-E PRECURSOR (MUCOSAL LYMPHOCYTE-1 ANTIGEN) (HML-1
ANTIGEN) (CD103 ANTIGEN) (INTEGRIN ALPHA-IEL)
gb|AAB59359.2| (L25851) integrin alpha E precursor [Homo sapiens]
Length = 1179
Score = 285 bits (722), Expect = 2e-75
Identities = 230/757 (30%), Positives = 360/757 (47%), Gaps = 75/757 (9%)
Query: 144 DIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
+I I+LDGS SI P D A F++++++ + +VQYG + EF+L
Sbjct: 202 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 261
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGES-HDNH 260
L + I Q G T TA FT + G+RR KVMV++TDG D
Sbjct: 262 VMASLARVQNITQVGS-VTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 320
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
L VI + + ++RF+I + + + + E+ IAS+P E H F V++ +AL
Sbjct: 321 NLTTVINSPKMQGVERFAIGVGEEFK-----SARTARELNLIASDPDETHAFKVTNYMAL 375
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQD-WVMLGAVGAYDWNGTVVM 379
++ L I ++E T + +++Q GFSA + V+LGAVGA+DW+G ++
Sbjct: 376 DGLLSKLRYNIISMEGTVGDA---LHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL 432
Query: 380 QKASQIIIPRNTTFNVESTKKNEPLA---SYLGYTVNSATASSGDVLYIAGQPRYNHTGQ 436
R N + + A SYLGY V + + + Y+AG P+Y H G
Sbjct: 433 YDTRS---RRGRFLNQTAAAAADAEAAQYSYLGYAV-AVLHKTCSLSYVAGAPQYKHHGA 488
Query: 437 VIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQG 496
V + E L L GEQ+GSYFGS L DID D +TD LLV AP Y E+G
Sbjct: 489 VFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEEG 546
Query: 497 KVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLD 556
+VYVY L++ + SL I H T ARFG A+AA+ DL+ D
Sbjct: 547 RVYVYRLSEQ--DGSFSLARILS------GHPGFT--------NARFGFAMAAMGDLSQD 590
Query: 557 GFNDIVIGAPLED---DHG---GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIH 610
D+ IGAPLE D G G+VYIY+G + +QRI + L++FG S+
Sbjct: 591 KLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMA 650
Query: 611 GEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCI 670
G D++GDGL D+T+G LG A +F SR V +KV+M F P+ + I +
Sbjct: 651 GGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNG---------VV 701
Query: 671 NATVCFEVK--LKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQE-----RKVQRNITV 723
N +CFE+ + E + EA L + + +D +Q R S + R+ +
Sbjct: 702 NVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQL 761
Query: 724 RKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPEN-----GPVLDDSLPNSVHEYIPFAK 778
+ + L + D + + + + L PE P+LD +P+ K
Sbjct: 762 CEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEK 821
Query: 779 DCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLV 838
C NK C+++L L ++++L++ ++ N++LT N+ + +Y T ++Y NL
Sbjct: 822 ACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLT--NSGEDSYMTSMALNYPRNLQ 879
Query: 839 FSGIEA-----IQKDSCESNHNI---TCKVGYPFLRR 867
++ IQ D + ++ C++G+P L+R
Sbjct: 880 LKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKR 916
>pir||A53213 integrin alpha-E chain - human
Length = 1178
Score = 285 bits (722), Expect = 2e-75
Identities = 230/757 (30%), Positives = 360/757 (47%), Gaps = 75/757 (9%)
Query: 144 DIVIVLDGSNSIYPWDSVTA--FLNDLLKRMDIGPKQTQVGIVQYGENVTHEFNLNKYSS 201
+I I+LDGS SI P D A F++++++ + +VQYG + EF+L
Sbjct: 201 EIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQD 260
Query: 202 TEEVLVAAKKIVQRGGRQTMTALGTDTARKEAFTEARGARRGVKKVMVIVTDGES-HDNH 260
L + I Q G T TA FT + G+RR KVMV++TDG D
Sbjct: 261 VMASLARVQNITQVGS-VTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPL 319
Query: 261 RLKKVIQDCEDENIQRFSIAILGSYNRGNLSTEKFVEEIKSIASEPTEKHFFNVSDELAL 320
L VI + + ++RF+I + + + + E+ IAS+P E H F V++ +AL
Sbjct: 320 NLTTVINSPKMQGVERFAIGVGEEFK-----SARTARELNLIASDPDETHAFKVTNYMAL 374
Query: 321 VTIVKTLGERIFALEATADQSAASFEMEMSQTGFSAHYSQD-WVMLGAVGAYDWNGTVVM 379
++ L I ++E T + +++Q GFSA + V+LGAVGA+DW+G ++
Sbjct: 375 DGLLSKLRYNIISMEGTVGDA---LHYQLAQIGFSAQILDERQVLLGAVGAFDWSGGALL 431
Query: 380 QKASQIIIPRNTTFNVESTKKNEPLA---SYLGYTVNSATASSGDVLYIAGQPRYNHTGQ 436
R N + + A SYLGY V + + + Y+AG P+Y H G
Sbjct: 432 YDTRS---RRGRFLNQTAAAAADAEAAQYSYLGYAV-AVLHKTCSLSYVAGAPQYKHHGA 487
Query: 437 VIIYRMEDGNIKILQTLSGEQIGSYFGSILTTTDIDKDSNTDILLVGAPMYMGTEKEEQG 496
V + E L L GEQ+GSYFGS L DID D +TD LLV AP Y E+G
Sbjct: 488 VFELQKEGREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFY--HVHGEEG 545
Query: 497 KVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLD 556
+VYVY L++ + SL I H T ARFG A+AA+ DL+ D
Sbjct: 546 RVYVYRLSEQ--DGSFSLARILS------GHPGFT--------NARFGFAMAAMGDLSQD 589
Query: 557 GFNDIVIGAPLED---DHG---GAVYIYHGSGKTIRKEYAQRIPSGGDGKTLKFFGQSIH 610
D+ IGAPLE D G G+VYIY+G + +QRI + L++FG S+
Sbjct: 590 KLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMA 649
Query: 611 GEMDLNGDGLTDVTIGGLGGAALFWSRDVAVVKVTMNFEPNKVNIQKKNCHMEGKETVCI 670
G D++GDGL D+T+G LG A +F SR V +KV+M F P+ + I +
Sbjct: 650 GGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNG---------VV 700
Query: 671 NATVCFEVK--LKSKEDTIYEADLQYRVTLDSLRQISRSFFSGTQE-----RKVQRNITV 723
N +CFE+ + E + EA L + + +D +Q R S + R+ +
Sbjct: 701 NVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQL 760
Query: 724 RKSECTKHSFYMLDKHDFQDSVRITLDFNLTDPEN-----GPVLDDSLPNSVHEYIPFAK 778
+ + L + D + + + + L PE P+LD +P+ K
Sbjct: 761 CEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEK 820
Query: 779 DCGNKEKCISDLSLHVATTEKDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLV 838
C NK C+++L L ++++L++ ++ N++LT N+ + +Y T ++Y NL
Sbjct: 821 ACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLT--NSGEDSYMTSMALNYPRNLQ 878
Query: 839 FSGIEA-----IQKDSCESNHNI---TCKVGYPFLRR 867
++ IQ D + ++ C++G+P L+R
Sbjct: 879 LKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKR 915
>pir||A49459 integrin alpha-9 chain - human
Length = 1006
Score = 231 bits (584), Expect = 3e-59
Identities = 231/861 (26%), Positives = 370/861 (42%), Gaps = 100/861 (11%)
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
Q G + ++++ V++GA G++ W GT+ + + NT + +YLGY
Sbjct: 166 QAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTD-----NTYLKLNDEVIMNRRYTYLGY 220
Query: 411 TVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGN---IKILQTLSGEQIGSYFGSIL 466
V + S + + G P+ G+V I+R + + IKI Q SG+++GSYFGS L
Sbjct: 221 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQA-SGKKMGSYFGSSL 279
Query: 467 TTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQ 526
D++ D +D LLVGAPM+ E Q VY+ N E Q++L
Sbjct: 280 CAVDLNGDGLSD-LLVGAPMFSEIRDEGQVTVYINRGNGA-LEEQLAL------------ 325
Query: 527 HNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIR 586
+ A FG +IA++ DL+ DGF D+ IGAP EDD GAVYIYHG I
Sbjct: 326 -------TGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIV 378
Query: 587 KEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKV 644
+Y+ ++ L+ FGQSI G +D++G+G DVT+G L +R V V V
Sbjct: 379 PQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV 438
Query: 645 TMNFEPNKVNIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLR-- 702
++ F P +NI CH + C+N T CF K + E L Y + D +
Sbjct: 439 SI-FLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPE---EIGLNYVLMADVAKKE 494
Query: 703 --QISRSFF--SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQD-------------SV 745
Q+ R +F G +V + + E T + K QD S
Sbjct: 495 KGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSE 554
Query: 746 RITLDFNLTDPENGPVLDDSLPNSVHE--YIPFAKDCGNKEKCISDLSLH-----VATTE 798
+T + P PVL + + F ++C E C +DL L + E
Sbjct: 555 HVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNC-RSEDCAADLQLQGKLLLSSMDE 613
Query: 799 KDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD----SCE--S 852
K L + ++++++ N D AY+ + S L F I QK+ SCE
Sbjct: 614 KTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLE 671
Query: 853 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLM---ENVTIYLSATSDSEEPPETLSDNV 909
+ + C VG+PF+R F ++ F+TS+L E ++ ++A S + E E+L DN
Sbjct: 672 SDFLKCSVGFPFMRSKSKYEFSVI--FDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNT 729
Query: 910 VNISIPVKYEVGLQFYSSASE----YHISIAANETVPEVINSTEDIGNEINIFYLIRKSG 965
+ + +P+ +EV S Y S+ A + ++ E INI + +G
Sbjct: 730 LVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQ--LDDLECHFQPINITLQVYNTG 787
Query: 966 SFPMPELKLSISFPNMTSNGYPVLYPTG--LSSSENANCRPHIFEDPFSINSGKK---MT 1020
+P +SISFPN S+G ++ + E NC P I ++ T
Sbjct: 788 PSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHT 847
Query: 1021 TSTDHLKRG-TILDCNTCKFATIT--CN---LTSSDISQVNVSLILWKPTFIKSYFSSLN 1074
K G +LDC + +T CN L + +++ ++L K S +
Sbjct: 848 IFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQ 907
Query: 1075 LTIRGELRSENASLVLSSSNQKRELAIQISKDGL-----PGRVPLWVIXXXXXXXXXXXX 1129
R +++ + A V+ ++ E + + + L G V W+I
Sbjct: 908 FMSRAKVKVDPALRVVEIAHGNPE-EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 966
Query: 1130 XXXXXXWKIGFFKRPLKKKME 1150
WK+GFF+R K+ +E
Sbjct: 967 LLAVLLWKMGFFRRRYKEIIE 987
Score = 50.8 bits (119), Expect = 8e-05
Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 15/126 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRT----GDVYKCPV 56
+N+D + + F GP + FGY V ++ ++ +WVL+G+P + + G V+KC V
Sbjct: 1 YNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRV 60
Query: 57 GRGESLPCVKLDLPVNTSI-----PNVTEVKENMTFGSTLVTNP--NGGFLACGPLYAYR 109
C +LD+ + E +++ G +L P +G LAC A+R
Sbjct: 61 HTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLAC----AHR 116
Query: 110 CGHLHY 115
+++Y
Sbjct: 117 WKNIYY 122
>sp|Q13797|ITA9_HUMAN INTEGRIN ALPHA-9 PRECURSOR (INTEGRIN ALPHA-RLC)
pir||I58409 integrin alpha-9 chain - human
dbj|BAA04984.1| (D25303) integrin alpha subunit [Homo sapiens]
Length = 1035
Score = 231 bits (584), Expect = 3e-59
Identities = 231/861 (26%), Positives = 370/861 (42%), Gaps = 100/861 (11%)
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
Q G + ++++ V++GA G++ W GT+ + + NT + +YLGY
Sbjct: 195 QAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTD-----NTYLKLNDEVIMNRRYTYLGY 249
Query: 411 TVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGN---IKILQTLSGEQIGSYFGSIL 466
V + S + + G P+ G+V I+R + + IKI Q SG+++GSYFGS L
Sbjct: 250 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQA-SGKKMGSYFGSSL 308
Query: 467 TTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQ 526
D++ D +D LLVGAPM+ E Q VY+ N E Q++L
Sbjct: 309 CAVDLNGDGLSD-LLVGAPMFSEIRDEGQVTVYINRGNGA-LEEQLAL------------ 354
Query: 527 HNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIR 586
+ A FG +IA++ DL+ DGF D+ IGAP EDD GAVYIYHG I
Sbjct: 355 -------TGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIV 407
Query: 587 KEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKV 644
+Y+ ++ L+ FGQSI G +D++G+G DVT+G L +R V V V
Sbjct: 408 PQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV 467
Query: 645 TMNFEPNKVNIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLR-- 702
++ F P +NI CH + C+N T CF K + E L Y + D +
Sbjct: 468 SI-FLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPE---EIGLNYVLMADVAKKE 523
Query: 703 --QISRSFF--SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQD-------------SV 745
Q+ R +F G +V + + E T + K QD S
Sbjct: 524 KGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSE 583
Query: 746 RITLDFNLTDPENGPVLDDSLPNSVHE--YIPFAKDCGNKEKCISDLSLH-----VATTE 798
+T + P PVL + + F ++C E C +DL L + E
Sbjct: 584 HVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNC-RSEDCAADLQLQGKLLLSSMDE 642
Query: 799 KDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD----SCE--S 852
K L + ++++++ N D AY+ + S L F I QK+ SCE
Sbjct: 643 KTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLE 700
Query: 853 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLM---ENVTIYLSATSDSEEPPETLSDNV 909
+ + C VG+PF+R F ++ F+TS+L E ++ ++A S + E E+L DN
Sbjct: 701 SDFLKCSVGFPFMRSKSKYEFSVI--FDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNT 758
Query: 910 VNISIPVKYEVGLQFYSSASE----YHISIAANETVPEVINSTEDIGNEINIFYLIRKSG 965
+ + +P+ +EV S Y S+ A + ++ E INI + +G
Sbjct: 759 LVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQ--LDDLECHFQPINITLQVYNTG 816
Query: 966 SFPMPELKLSISFPNMTSNGYPVLYPTG--LSSSENANCRPHIFEDPFSINSGKK---MT 1020
+P +SISFPN S+G ++ + E NC P I ++ T
Sbjct: 817 PSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHT 876
Query: 1021 TSTDHLKRG-TILDCNTCKFATIT--CN---LTSSDISQVNVSLILWKPTFIKSYFSSLN 1074
K G +LDC + +T CN L + +++ ++L K S +
Sbjct: 877 IFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQ 936
Query: 1075 LTIRGELRSENASLVLSSSNQKRELAIQISKDGL-----PGRVPLWVIXXXXXXXXXXXX 1129
R +++ + A V+ ++ E + + + L G V W+I
Sbjct: 937 FMSRAKVKVDPALRVVEIAHGNPE-EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 995
Query: 1130 XXXXXXWKIGFFKRPLKKKME 1150
WK+GFF+R K+ +E
Sbjct: 996 LLAVLLWKMGFFRRRYKEIIE 1016
Score = 50.8 bits (119), Expect = 8e-05
Identities = 33/126 (26%), Positives = 60/126 (47%), Gaps = 15/126 (11%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRT----GDVYKCPV 56
+N+D + + F GP + FGY V ++ ++ +WVL+G+P + + G V+KC V
Sbjct: 30 YNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRV 89
Query: 57 GRGESLPCVKLDLPVNTSI-----PNVTEVKENMTFGSTLVTNP--NGGFLACGPLYAYR 109
C +LD+ + E +++ G +L P +G LAC A+R
Sbjct: 90 HTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLAC----AHR 145
Query: 110 CGHLHY 115
+++Y
Sbjct: 146 WKNIYY 151
>gb|AAA16099.1| (L24158) integrin alpha 9 protein [Homo sapiens]
Length = 1000
Score = 231 bits (584), Expect = 3e-59
Identities = 231/861 (26%), Positives = 370/861 (42%), Gaps = 100/861 (11%)
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
Q G + ++++ V++GA G++ W GT+ + + NT + +YLGY
Sbjct: 160 QAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTD-----NTYLKLNDEVIMNRRYTYLGY 214
Query: 411 TVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGN---IKILQTLSGEQIGSYFGSIL 466
V + S + + G P+ G+V I+R + + IKI Q SG+++GSYFGS L
Sbjct: 215 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQA-SGKKMGSYFGSSL 273
Query: 467 TTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQ 526
D++ D +D LLVGAPM+ E Q VY+ N E Q++L
Sbjct: 274 CAVDLNGDGLSD-LLVGAPMFSEIRDEGQVTVYINRGNGA-LEEQLAL------------ 319
Query: 527 HNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIR 586
+ A FG +IA++ DL+ DGF D+ IGAP EDD GAVYIYHG I
Sbjct: 320 -------TGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIV 372
Query: 587 KEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKV 644
+Y+ ++ L+ FGQSI G +D++G+G DVT+G L +R V V V
Sbjct: 373 PQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV 432
Query: 645 TMNFEPNKVNIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLR-- 702
++ F P +NI CH + C+N T CF K + E L Y + D +
Sbjct: 433 SI-FLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPE---EIGLNYVLMADVAKKE 488
Query: 703 --QISRSFF--SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQD-------------SV 745
Q+ R +F G +V + + E T + K QD S
Sbjct: 489 KGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSE 548
Query: 746 RITLDFNLTDPENGPVLDDSLPNSVHE--YIPFAKDCGNKEKCISDLSLH-----VATTE 798
+T + P PVL + + F ++C E C +DL L + E
Sbjct: 549 HVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNC-RSEDCAADLQLQGKLLLSSMDE 607
Query: 799 KDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD----SCE--S 852
K L + ++++++ N D AY+ + S L F I QK+ SCE
Sbjct: 608 KTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLE 665
Query: 853 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLM---ENVTIYLSATSDSEEPPETLSDNV 909
+ + C VG+PF+R F ++ F+TS+L E ++ ++A S + E E+L DN
Sbjct: 666 SDFLKCSVGFPFMRSKSKYEFSVI--FDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNT 723
Query: 910 VNISIPVKYEVGLQFYSSASE----YHISIAANETVPEVINSTEDIGNEINIFYLIRKSG 965
+ + +P+ +EV S Y S+ A + ++ E INI + +G
Sbjct: 724 LVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQ--LDDLECHFQPINITLQVYNTG 781
Query: 966 SFPMPELKLSISFPNMTSNGYPVLYPTG--LSSSENANCRPHIFEDPFSINSGKK---MT 1020
+P +SISFPN S+G ++ + E NC P I ++ T
Sbjct: 782 PSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHT 841
Query: 1021 TSTDHLKRG-TILDCNTCKFATIT--CN---LTSSDISQVNVSLILWKPTFIKSYFSSLN 1074
K G +LDC + +T CN L + +++ ++L K S +
Sbjct: 842 IFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQ 901
Query: 1075 LTIRGELRSENASLVLSSSNQKRELAIQISKDGL-----PGRVPLWVIXXXXXXXXXXXX 1129
R +++ + A V+ ++ E + + + L G V W+I
Sbjct: 902 FMSRAKVKVDPALRVVEIAHGNPE-EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 960
Query: 1130 XXXXXXWKIGFFKRPLKKKME 1150
WK+GFF+R K+ +E
Sbjct: 961 LLAVLLWKMGFFRRRYKEIIE 981
Score = 45.7 bits (106), Expect = 0.003
Identities = 31/116 (26%), Positives = 54/116 (45%), Gaps = 15/116 (12%)
Query: 11 FSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRT----GDVYKCPVGRGESLPCVK 66
F GP + FGY V ++ ++ +WVL+G+P + + G V+KC V C +
Sbjct: 5 FQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTE 64
Query: 67 LDLPVNTSI-----PNVTEVKENMTFGSTLVTNP--NGGFLACGPLYAYRCGHLHY 115
LD+ + E +++ G +L P +G LAC A+R +++Y
Sbjct: 65 LDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLAC----AHRWKNIYY 116
>ref|NP_034706.1| integrin alpha 4 (Cd49d); VLA-4 receptor, alpha 4 subunit [Mus
musculus]
gb|AAB09630.1| (U33451) alpha-4 integrin [Mus musculus]
gb|AAC95388.1| (AF109136) integrin alpha-4 subunit precursor [Mus musculus]
Length = 1032
Score = 226 bits (569), Expect = 1e-57
Identities = 190/668 (28%), Positives = 308/668 (45%), Gaps = 74/668 (11%)
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
Q G S+ Y+QD +++GA G+ W GTV + I N + SYLGY
Sbjct: 199 QAGISSFYTQDLIVMGAPGSSYWTGTVFVYN-----ITTNQYKAFVDRQNQVKFGSYLGY 253
Query: 411 TVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTT 469
+V + S + G P++ G+ I+ +++ + I+ + G+++GSYFG+ +
Sbjct: 254 SVGAGHFRSPHTTEVVGGAPQHEQIGKAYIFSIDENELNIVYEMKGKKLGSYFGASVCAV 313
Query: 470 DIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNS 529
D++ D +D LLVGAPM + E+G+V+VY +N + +E +
Sbjct: 314 DLNADGFSD-LLVGAPMQ--STIREEGRVFVY-INSGMGAVMVEMERVLVG--------- 360
Query: 530 CTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEY 589
++ ARFG +IA + D++ DGF DI IGAP EDD GAVYIY+G I Y
Sbjct: 361 ------SDKYAARFGESIANLGDIDNDGFEDIAIGAPQEDDLRGAVYIYNGRVDGISSTY 414
Query: 590 AQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKVTMN 647
+QRI K+L+ FGQSI G++D + +G DV +G A L +R V +V+ +++
Sbjct: 415 SQRIEGQQISKSLRMFGQSISGQIDADNNGYVDVAVGAFQSDSAVLLRTRPVVIVEASLS 474
Query: 648 FEPNKVNIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRS 707
P VN K +C G +VC++ T+CF K K I L Y V+LD R+
Sbjct: 475 -HPESVNRTKFDCTENGLPSVCMHLTLCFSYKGKEVPGYIV---LFYNVSLDVHRKAESP 530
Query: 708 ----FFSGTQERKVQRNITVRKS--ECTKHSFYM-LDKHDFQDSVRITLDFNL------- 753
FFS + +I V S +C H +M D D + + ++L
Sbjct: 531 SRFYFFSNGTSDVITGSIRVSSSGEKCRTHQAFMRKDVRDILTPIHVEATYHLGHHVITK 590
Query: 754 TDPENGPVLDDSLPNS-----VHEYIPFAKDCGNKEKCISDLSLHVAT------TEKDLL 802
+ E P L L + + I FA+ C E C +DL + K L
Sbjct: 591 RNTEEFPPLQPILQQKKEKDVIRKMINFARFCA-YENCSADLQVSAKVGFLKPYENKTYL 649
Query: 803 IVRSQND-KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--SCESNHN---- 855
V S NVSL N D AY T V L F I +++ +CE +
Sbjct: 650 AVGSMKTIMLNVSLF--NAGDDAYETTLNVQLPTGLYFIKILDLEEKQINCEVTESSGIV 707
Query: 856 -ITCKVGYPFLRRGEMVTFKILFQFNT-SYLMENVTIYLSATSDSEEPPETLSDNVVNIS 913
+ C +GY ++ R + L ++ S E+++I + A+ ++E + + DN V ++
Sbjct: 708 KLACSLGYIYVDRLSRIDISFLLDVSSLSRAHEDLSISVHASCENEGELDQVRDNRVTLT 767
Query: 914 IPVKYEVGLQFYSSAS-EYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPEL 972
IP++YEV L + + + ++ E PE + ++N+ + + +G P +
Sbjct: 768 IPLRYEVMLTVHGLVNPTSFVYGSSEENEPETC-----MAEKLNLTFHVINTGISMAPNV 822
Query: 973 KLSISFPN 980
+ I PN
Sbjct: 823 SVKIMVPN 830
Score = 59.3 bits (141), Expect = 2e-07
Identities = 35/132 (26%), Positives = 62/132 (46%), Gaps = 12/132 (9%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRT----GDVYKCPV 56
+N+D +N++ + GP +FGY+V + + +W+++G+P N + G +Y+C +
Sbjct: 34 YNLDPENALLYQGPSGTLFGYSVVLHSHGSKRWLIVGAPTASWLSNASVVNPGAIYRCGI 93
Query: 57 GRGESLPCVKLDLPVNTSIP---NVTEVKENMTFGSTLVTNP--NGGFLACGPLYA---Y 108
+ + C +L L + P E ++N G TL P NG + CG + Y
Sbjct: 94 RKNPNQTCEQLQLGSPSGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFY 153
Query: 109 RCGHLHYTTGIC 120
TGIC
Sbjct: 154 MKSDNKLPTGIC 165
>sp|Q00651|ITA4_MOUSE INTEGRIN ALPHA-4 PRECURSOR (INTEGRIN ALPHA-IV) (VLA-4) (CD49D)
(LYMPHOCYTE-PEYER'S PATCH ADHESION MOLECULES ALPHA
SUBUNIT) (LPAM ALPHA SUBUNIT)
pir||A41131 lymphocyte-Peyer's patch adhesion molecule alpha 4 precursor -
mouse
emb|CAA37316.1| (X53176) LPAM Alpha Chain [Mus musculus]
Length = 1039
Score = 226 bits (569), Expect = 1e-57
Identities = 190/668 (28%), Positives = 308/668 (45%), Gaps = 74/668 (11%)
Query: 351 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 410
Q G S+ Y+QD +++GA G+ W GTV + I N + SYLGY
Sbjct: 206 QAGISSFYTQDLIVMGAPGSSYWTGTVFVYN-----ITTNQYKAFVDRQNQVKFGSYLGY 260
Query: 411 TVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGNIKILQTLSGEQIGSYFGSILTTT 469
+V + S + G P++ G+ I+ +++ + I+ + G+++GSYFG+ +
Sbjct: 261 SVGAGHFRSPHTTEVVGGAPQHEQIGKAYIFSIDENELNIVYEMKGKKLGSYFGASVCAV 320
Query: 470 DIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQHNS 529
D++ D +D LLVGAPM + E+G+V+VY +N + +E +
Sbjct: 321 DLNADGFSD-LLVGAPMQ--STIREEGRVFVY-INSGMGAVMVEMERVLVG--------- 367
Query: 530 CTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIRKEY 589
++ ARFG +IA + D++ DGF DI IGAP EDD GAVYIY+G I Y
Sbjct: 368 ------SDKYAARFGESIANLGDIDNDGFEDIAIGAPQEDDLRGAVYIYNGRVDGISSTY 421
Query: 590 AQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKVTMN 647
+QRI K+L+ FGQSI G++D + +G DV +G A L +R V +V+ +++
Sbjct: 422 SQRIEGQQISKSLRMFGQSISGQIDADNNGYVDVAVGAFQSDSAVLLRTRPVVIVEASLS 481
Query: 648 FEPNKVNIQKKNCHMEGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTLDSLRQISRS 707
P VN K +C G +VC++ T+CF K K I L Y V+LD R+
Sbjct: 482 -HPESVNRTKFDCTENGLPSVCMHLTLCFSYKGKEVPGYIV---LFYNVSLDVHRKAESP 537
Query: 708 ----FFSGTQERKVQRNITVRKS--ECTKHSFYM-LDKHDFQDSVRITLDFNL------- 753
FFS + +I V S +C H +M D D + + ++L
Sbjct: 538 SRFYFFSNGTSDVITGSIRVSSSGEKCRTHQAFMRKDVRDILTPIHVEATYHLGHHVITK 597
Query: 754 TDPENGPVLDDSLPNS-----VHEYIPFAKDCGNKEKCISDLSLHVAT------TEKDLL 802
+ E P L L + + I FA+ C E C +DL + K L
Sbjct: 598 RNTEEFPPLQPILQQKKEKDVIRKMINFARFCA-YENCSADLQVSAKVGFLKPYENKTYL 656
Query: 803 IVRSQND-KFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD--SCESNHN---- 855
V S NVSL N D AY T V L F I +++ +CE +
Sbjct: 657 AVGSMKTIMLNVSLF--NAGDDAYETTLNVQLPTGLYFIKILDLEEKQINCEVTESSGIV 714
Query: 856 -ITCKVGYPFLRRGEMVTFKILFQFNT-SYLMENVTIYLSATSDSEEPPETLSDNVVNIS 913
+ C +GY ++ R + L ++ S E+++I + A+ ++E + + DN V ++
Sbjct: 715 KLACSLGYIYVDRLSRIDISFLLDVSSLSRAHEDLSISVHASCENEGELDQVRDNRVTLT 774
Query: 914 IPVKYEVGLQFYSSAS-EYHISIAANETVPEVINSTEDIGNEINIFYLIRKSGSFPMPEL 972
IP++YEV L + + + ++ E PE + ++N+ + + +G P +
Sbjct: 775 IPLRYEVMLTVHGLVNPTSFVYGSSEENEPETC-----MAEKLNLTFHVINTGISMAPNV 829
Query: 973 KLSISFPN 980
+ I PN
Sbjct: 830 SVKIMVPN 837
Score = 57.0 bits (135), Expect = 1e-06
Identities = 34/132 (25%), Positives = 61/132 (45%), Gaps = 12/132 (9%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRT----GDVYKCPV 56
+N+D +N++ + GP +FGY+V + + +W+++G+P N + G +Y+C +
Sbjct: 41 YNLDPENALLYQGPSGTLFGYSVVLHSHGSKRWLIVGAPTASWLSNASVVNPGAIYRCGI 100
Query: 57 GRGESLPCVKLDLPVNTSIP---NVTEVKENMTFGSTLVTNP--NGGFLACGPLYA---Y 108
+ + C +L + P E ++N G TL P NG + CG + Y
Sbjct: 101 RKNPNQTCEQLQSGSPSGEPCGKTCLEERDNQWLGVTLSRQPGENGSIVTCGHRWKNIFY 160
Query: 109 RCGHLHYTTGIC 120
TGIC
Sbjct: 161 MKSDNKLPTGIC 172
>gb|AAD22567.1|U22152_1 (U22152) alpha-Lv1 integrin [Lytechinus variegatus]
Length = 1041
Score = 224 bits (565), Expect = 4e-57
Identities = 226/863 (26%), Positives = 365/863 (42%), Gaps = 96/863 (11%)
Query: 351 QTGFSAHYSQD--WVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYL 408
Q GFS D +++GA G+Y G + +Q + + T + T + SY
Sbjct: 181 QAGFSGXIXSDNSALVMGAPGSYYLQGQIYVQSLLNRSVVQATQESNTGTYSFDN--SYR 238
Query: 409 GYTVNSATASSGDVL-YIAGQPRYNHT-GQVIIYRMEDGNIKILQTLSGEQIGSYFGSIL 466
GY++ + V Y+ G PR G V I+ D N+ + G QI +YFG +
Sbjct: 239 GYSLALGDFNGDGVQDYVVGTPRAESLMGLVAIF---DQNLNQFNQVMGTQIVAYFGYSV 295
Query: 467 TTTDIDKDSNTDILLVGAPMYM----GTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCC 522
T DI+ D+ D LLVGAPMYM ++ E G VYVY N P
Sbjct: 296 TVVDINNDTYDD-LLVGAPMYMDDGPAIQRWEAGAVYVYLQN-----------PDVGPGA 343
Query: 523 SSRQHNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSG 582
S+R S T +RFG +IA++ D N DGFND+ IGAP E D GAVYIYHGS
Sbjct: 344 SNRLSLSSTLIGGQ--IRSRFGLSIASIGDSNQDGFNDVAIGAPYEGDDAGAVYIYHGSA 401
Query: 583 KTIRKEYAQRI-PSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIG--GLGGAALFWSRDV 639
++ AQ + PS + FG S+ G D++ + D+ +G A L +R V
Sbjct: 402 NGLKSTPAQVLTPSTLGHSGITTFGFSLQGGQDMDKNKYPDLLVGAESANTAVLIRTRPV 461
Query: 640 AVVKVTMNFEPNKVNIQKKNCHM-EGKETVCINATVCFEVKLKSKEDTIYEADLQYRVTL 698
+ T+N EP +N++ K + +G A CF D I D+ Y VT+
Sbjct: 462 VSLDATLNTEPIGINLENKTYELADGTMVTSFIAMTCFTYTGNYLPDHI---DISYTVTV 518
Query: 699 DS-LRQISRSFF--SGTQERKVQRNITVRKSECTKHSFYMLDK-HDFQDSVRITLDFNLT 754
DS + R+ F + E R + V C Y+ + D +++TL ++L
Sbjct: 519 DSGIIANRRAMFVDNDMSEITKTRXLAVSTQFCDPLRAYVGNSIEDKLTPIKVTLQYDLN 578
Query: 755 DPENG-------PVLDDSLPNSVHEYIPFAKDCGNKEKCISDLSLHVATTEKDLLIVRSQ 807
+ E+ P++D + ++ + + +C N CI DL + V +++I ++Q
Sbjct: 579 NDESRLQPHEILPIIDMATMSTQTKQVSIQNNCVN-NICIPDLDVTVTPNLPNIVIGQTQ 637
Query: 808 NDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQ----KDSCESNHN---ITCKV 860
+VSL N + A+ + V+Y L F +E +C + + ITC
Sbjct: 638 ELTLDVSL--NNRGEDAFQSSLSVYYPLGLQFVRLERKANMDFSVTCSEDSDLRIITCDT 695
Query: 861 GYPFLRRGEMVTFKILFQFNTSYLMENVTIYLSATSDSEEPPETLSDNVVNISIPVKYEV 920
G P + + + L F S +++ Y A S++ E P TL +N +N+++PV +
Sbjct: 696 GNPMVGKNILEFGLTLSTFQVSGDKDSIEFYFKAESENSEDPNTLENNELNMTVPVTVDC 755
Query: 921 GLQFYSSASEYHISIAANE-----TVPEVINSTEDIGNEINIFYLIRKSGSFPMPELKLS 975
L+ S++ + + E P S DIG E+ Y +R +GS E+ L+
Sbjct: 756 TLKLLSASYPEIVMYSTQEDYVVPPFPAKNASEADIGMEVMHLYEVRNTGSSNAGEVSLN 815
Query: 976 ISFPNMTSNGYPVLYPTGLSSSENANCR--------PHIFEDPFSINSGKKMTTSTDHLK 1027
I +P +G + Y G+ + E C+ + +P + TT K
Sbjct: 816 IQWPQKNEDGEYLFYLLGIMTEEGVTCQLTQGKANPEGVKLEPSTKAKLSNSTTQVSGRK 875
Query: 1028 R------------GTILDCNTCKFATITCNLTSSDISQVNVSLIL---WKPTFIKSYFSS 1072
R ++ C + I C + + S+ V IL W+ TF K+ S
Sbjct: 876 RREPEVAEALAQTDNVIYCASDSCVLINCTIDEINASKSKVVRILGRFWERTFQKA-VSE 934
Query: 1073 LNLTIRGELRSE----------NASLVLSSSNQKRELAIQISKDGLPGRVPL--WVIXXX 1120
L ++ + S N L S+ + + +++ +P P+ W+I
Sbjct: 935 LTPVVQATIASSASAAVKTIPYNIPLPRDFSDSTKASTLVTTEELVPPVTPIAWWIIVVS 994
Query: 1121 XXXXXXXXXXXXXXXWKIGFFKR 1143
WK GFF+R
Sbjct: 995 VLGGIILLLIIILGLWKCGFFER 1017
Score = 53.9 bits (127), Expect = 1e-05
Identities = 36/109 (33%), Positives = 55/109 (50%), Gaps = 8/109 (7%)
Query: 1 FNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKN---RTGDVYK-CPV 56
FN D++ + F GP MFG++V Q+ + W L+G+P ++ + G VY C
Sbjct: 21 FNFDLRAPLKFDGPDGSMFGFSVAQHRDGNTDWALVGAPEASTNQSGVTKGGAVYSVCRP 80
Query: 57 GRGESLPCVKLDLPVNTSIPNVTEVKENMTFGSTLVT-NPNGGFLACGP 104
G S+ C ++ +I NV K N FG+T+ + NG LAC P
Sbjct: 81 LSGPSV-CEQIPFDKTGNINNVD--KSNQWFGATVASGGANGQILACAP 126
Database: nr
Number of letters in database: 183,345,511
Number of sequences in database: 582,290
Lambda K H
0.316 0.133 0.386
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 410068617
Number of Sequences: 582290
Number of extensions: 18220800
Number of successful extensions: 42873
Number of sequences better than 10.0: 359
Number of HSP's better than 10.0 without gapping: 263
Number of HSP's successfully gapped in prelim test: 96
Number of HSP's that attempted gapping in prelim test: 40583
Number of HSP's gapped (non-prelim): 853
length of query: 1151
length of database: 183,345,511
effective HSP length: 61
effective length of query: 1090
effective length of database: 147,825,821
effective search space: 161130144890
effective search space used: 161130144890
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.6 bits)
S2: 76 (34.0 bits)
