Score E
Sequences producing significant alignments: (bits) Value
dbj|BAA35186.1| (AB017169) Slit-3 protein [Homo sapiens] 3032 0.0
gb|AAD44760.1|AF144629_1 (AF144629) SLIT3 [Mus musculus] 2884 0.0
pir||T13953 MEGF5 protein - rat >gi|3449292|dbj|BAA32461.1|... 2879 0.0
gb|AAD25539.1|AF133270_1 (AF133270) SLIT2 [Homo sapiens] 2110 0.0
gb|AAD44759.1|AF144628_1 (AF144628) SLIT2 [Mus musculus] 2107 0.0
ref|NP_004778.1| slit (Drosophila) homolog 2 [Homo sapiens]... 2107 0.0
gb|AAD04309.1| (AF055585) neurogenic extracellular slit pro... 2107 0.0
ref|NP_003052.1| slit (Drosophila) homolog 1; slit1 [Homo s... 1875 0.0
pir||T42218 slit-1 protein homolog - rat >gi|3449290|dbj|BA... 1865 0.0
gb|AAD44758.1|AF144627_1 (AF144627) SLIT1 [Mus musculus] 1854 0.0
gb|AAD25540.1|AF133730_1 (AF133730) Slit1 [Rattus norvegicus] 1829 0.0
dbj|BAA32466.1| (AB011538) MEGF5 [Homo sapiens] 1517 0.0
gb|AAD19336.1| (AF075240) SLIT1 protein [Homo sapiens] 1395 0.0
gb|AAD04345.1| (AF074960) neurogenic extracellular slit pro... 1378 0.0
gb|AAF58097.1| (AE003809) sli gene product [alt 1] [Drosoph... 1204 0.0
gb|AAD26567.1|AF126540_1 (AF126540) slit protein [Drosophil... 1203 0.0
gb|AAF58098.1| (AE003809) sli gene product [alt 2] [Drosoph... 1170 0.0
pir||B36665 slit protein 2 precursor - fruit fly (Drosophil... 1160 0.0
sp|P24014|SLIT_DROME SLIT PROTEIN PRECURSOR >gi|103391|pir|... 1160 0.0
prf||1704200A slit gene [Drosophila sp.] 1153 0.0
gb|AAD38940.2| (AF141386) SLIT-2 [Rattus norvegicus] 1141 0.0
emb|CAA93668.2| (Z69792) Similarity to Drosophila EGF-like ... 916 0.0
dbj|BAA32465.2| (AB011537) MEGF4 [Homo sapiens] 737 0.0
pir||T34555 hypothetical protein DKFZp434N0435.1 - human >g... 615 e-174
pir||A31640 epidermal growth factor-like protein slit - fru... 355 2e-96
pir||T22025 hypothetical protein F40E10.4 - Caenorhabditis ... 291 4e-77
gb|AAD19349.1| (AF088902) SLIT1 protein [Mus musculus] 203 1e-50
sp|Q07008|NTC1_RAT NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1... 199 2e-49
pir||S18188 notch protein homolog - rat 199 2e-49
ref|NP_032740.1| Notch gene homolog 1, (Drosophila) [Mus mu... 198 3e-49
gb|AAF27299.1| (AF146429) DeltaC [Danio rerio] 196 2e-48
gb|AAA62163.1| (L08692) fibropellin Ib [Strongylocentrotus ... 195 4e-48
pir||A29316 epidermal growth factor homolog - sea urchin (S... 195 4e-48
dbj|BAA21713.1| (D87558) C-Serrate-2 [Gallus gallus] 194 8e-48
sp|P10079|FBP1_STRPU FIBROPELLIN I PRECURSOR (EPIDERMAL GRO... 193 1e-47
gb|AAC36151.1| (U58977) Notch homolog Scalloped wings [Luci... 192 2e-47
sp|P21783|NOTC_XENLA NEUROGENIC LOCUS NOTCH PROTEIN HOMOLOG... 192 2e-47
pir||A35844 Xotch protein - African clawed frog 192 2e-47
gb|AAB84216.1| (AF029779) hJAG2.del-E6 [Homo sapiens] 191 5e-47
gb|AAA29996.1| (L33862) fibropellin III [Heliocidaris eryth... 190 1e-46
sp|P46531|NTC1_HUMAN NEUROGENIC LOCUS NOTCH PROTEIN HOMOLOG... 190 1e-46
pir||A40043 notch protein homolog TAN-1 precursor - human 187 6e-46
gb|AAF45848.2| (AE003426) N gene product [Drosophila melano... 187 1e-45
ref|NP_036208.1| crumbs (Drosophila) homolog 1 [Homo sapien... 187 1e-45
emb|CAB37610.1| (AL035436) EG:140G11.1 [Drosophila melanoga... 187 1e-45
sp|P07207|NOTC_DROME NEUROGENIC LOCUS NOTCH PROTEIN PRECURS... 187 1e-45
pir||A24420 notch protein - fruit fly (Drosophila melanogas... 187 1e-45
emb|CAA71380.1| (Y10354) Notch receptor protein [Danio rerio] 186 2e-45
ref|NP_002217.1| jagged 2 [Homo sapiens] >gi|2432002|gb|AAB... 185 2e-45
gb|AAA29995.1| (L33861) fibropellin Ia [Heliocidaris erythr... 185 2e-45
>dbj|BAA35186.1| (AB017169) Slit-3 protein [Homo sapiens]
Length = 1523
Score = 3032 bits (7774), Expect = 0.0
Identities = 1444/1523 (94%), Positives = 1444/1523 (94%)
Query: 1 MAPGWXXXXXXXXXXXXXXXXXXXXXXXXXXVACPTKCTCSAASVDCHGLGLRAVPRGIP 60
MAPGW VACPTKCTCSAASVDCHGLGLRAVPRGIP
Sbjct: 1 MAPGWAGVGAAVRARLALALALASVLSGPPAVACPTKCTCSAASVDCHGLGLRAVPRGIP 60
Query: 61 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK
Sbjct: 61 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
Query: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 180
LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL
Sbjct: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 180
Query: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT 240
RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT
Sbjct: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT 240
Query: 241 LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGLME 300
LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGLME
Sbjct: 241 LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGLME 300
Query: 301 IPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSL 360
IPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSL
Sbjct: 301 IPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSL 360
Query: 361 VLYGNKITEIAKGXXXXXXXXXXXXXNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK 420
VLYGNKITEIAKG NANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK
Sbjct: 361 VLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK 420
Query: 421 GLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKS 480
GLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKS
Sbjct: 421 GLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKS 480
Query: 481 KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN 540
KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN
Sbjct: 481 KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN 540
Query: 541 DNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRV 600
DNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRV
Sbjct: 541 DNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRV 600
Query: 601 FRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL 660
FRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL
Sbjct: 601 FRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL 660
Query: 661 LSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQ 720
LSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQ
Sbjct: 661 LSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQ 720
Query: 721 LSPRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLI 780
LSPRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLI
Sbjct: 721 LSPRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLI 780
Query: 781 DLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPE 840
DLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPE
Sbjct: 781 DLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPE 840
Query: 841 GSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPT 900
GSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPT
Sbjct: 841 GSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPT 900
Query: 901 HRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCI 960
HRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCI
Sbjct: 901 HRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCI 960
Query: 961 QNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVC 1020
QNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQR ATCVDGINNYVC
Sbjct: 961 QNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVC 1020
Query: 1021 ICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVA 1080
ICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVA
Sbjct: 1021 ICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVA 1080
Query: 1081 HKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQE 1140
HKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQE
Sbjct: 1081 HKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQE 1140
Query: 1141 PTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGD 1200
PTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGD
Sbjct: 1141 PTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGD 1200
Query: 1201 NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPK 1260
NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHS DKGTPK
Sbjct: 1201 NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPK 1260
Query: 1261 SLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKA 1320
SLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKA
Sbjct: 1261 SLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKA 1320
Query: 1321 LPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG 1380
LPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG
Sbjct: 1321 LPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG 1380
Query: 1381 KCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 1440
KCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG
Sbjct: 1381 KCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 1440
Query: 1441 EHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECRXXXXXXXXXXTRSKRRKYVFQ 1500
EHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECR TRSKRRKYVFQ
Sbjct: 1441 EHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQ 1500
Query: 1501 CTDGSSFVEEVERHLECGCLACS 1523
CTDGSSFVEEVERHLECGCLACS
Sbjct: 1501 CTDGSSFVEEVERHLECGCLACS 1523
>gb|AAD44760.1|AF144629_1 (AF144629) SLIT3 [Mus musculus]
Length = 1523
Score = 2884 bits (7394), Expect = 0.0
Identities = 1358/1491 (91%), Positives = 1399/1491 (93%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL
Sbjct: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
EDNQVS+IERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA
Sbjct: 93 EDNQVSIIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG+T VKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL
Sbjct: 153 FRGVTGVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPS 272
HSNHLYCDCHLAWLSDWLRQRRT+GQFTLCMAPVHLRGF+VADVQKKEYVCP PHSE P+
Sbjct: 213 HSNHLYCDCHLAWLSDWLRQRRTIGQFTLCMAPVHLRGFSVADVQKKEYVCPGPHSEAPA 272
Query: 273 CNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
CNANS+SCPS C+CSNNIVDCRGKGL EIPANLPEGIVEIRLEQNSIK+IPAGAFTQYKK
Sbjct: 273 CNANSLSCPSACSCSNNIVDCRGKGLTEIPANLPEGIVEIRLEQNSIKSIPAGAFTQYKK 332
Query: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKIN 392
LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEI KG NANKIN
Sbjct: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKGLFDGLVSLQLLLLNANKIN 392
Query: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
CLRVNTFQDLQNLNLLSLYDNKLQTISKGLF PLQSIQTLHLAQNPFVCDCHLKWLADYL
Sbjct: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFVPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
Query: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCE 512
QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYR+RFSSECFMDLVCPEKCRCE
Sbjct: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRNRFSSECFMDLVCPEKCRCE 512
Query: 513 GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEV 572
GTIVDCSNQKL RIPSHLPEY TDLRLNDN++SVLEATGIFKKLPNLRKINLSNN+IKEV
Sbjct: 513 GTIVDCSNQKLARIPSHLPEYTTDLRLNDNDISVLEATGIFKKLPNLRKINLSNNRIKEV 572
Query: 573 REGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVR 632
REGAFDGAASVQELMLTGNQLET+HGR+FRGLSGLKTLMLRSNLI CVSNDTFAGLSSVR
Sbjct: 573 REGAFDGAASVQELMLTGNQLETMHGRMFRGLSGLKTLMLRSNLISCVSNDTFAGLSSVR 632
Query: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQK 692
LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCH+AWLG+WLRKRRIVSGNPRCQK
Sbjct: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHMAWLGRWLRKRRIVSGNPRCQK 692
Query: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPK 752
PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQ TC+ETVVRCSN+GL ALP+GMPK
Sbjct: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQFTCVETVVRCSNRGLHALPKGMPK 752
Query: 753 DVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLR 812
DVTELYLEGNHLTAVP+ELSA R LTLIDLSNNSISMLTN+TFSNMSHLSTLILSYNRLR
Sbjct: 753 DVTELYLEGNHLTAVPKELSAFRQLTLIDLSNNSISMLTNHTFSNMSHLSTLILSYNRLR 812
Query: 813 CIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWV 872
CIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWV
Sbjct: 813 CIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWV 872
Query: 873 KAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCT 932
KAGYKEPGIARCSSPE MADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC+
Sbjct: 873 KAGYKEPGIARCSSPESMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCS 932
Query: 933 QDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQR 992
QDPVE YRC CPYSYKGKDCTVPINTC+QNPC+HGGTCHLS++ +DGFSCSCPLGFEGQR
Sbjct: 933 QDPVEQYRCTCPYSYKGKDCTVPINTCVQNPCEHGGTCHLSENLRDGFSCSCPLGFEGQR 992
Query: 993 XXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCI 1052
ATCVDGINNY C+CPPNYTGELCDEVID+CVPE+NLCQHEAKCI
Sbjct: 993 CEINPDGCEDNDCENSATCVDGINNYACLCPPNYTGELCDEVIDYCVPEMNLCQHEAKCI 1052
Query: 1053 PLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHP 1112
LDKGF CECVPGYSGKLCET+NDDCVAHKCRHGAQCVD +NGYTC CPQGFSG FCEHP
Sbjct: 1053 SLDKGFRCECVPGYSGKLCETNNDDCVAHKCRHGAQCVDEVNGYTCICPQGFSGLFCEHP 1112
Query: 1113 PPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELA 1172
PPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELA
Sbjct: 1113 PPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELA 1172
Query: 1173 SAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVET 1232
SAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVET
Sbjct: 1173 SAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVET 1232
Query: 1233 VNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALR 1292
VNDGQFHS DKG PKSLGKLQKQPAVG NSPLYLGGIPTSTGLSALR
Sbjct: 1233 VNDGQFHSVKLVMLNQTLNLVVDKGAPKSLGKLQKQPAVGSNSPLYLGGIPTSTGLSALR 1292
Query: 1293 QGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVV 1352
QG DRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVC+HGLCRSVEKDSVV
Sbjct: 1293 QGADRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVV 1352
Query: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANAC 1412
CEC PGWTGPLCDQEARDPCLGH C HG C+ATG SY+CKCAEGYGG LCD KNDSA+AC
Sbjct: 1353 CECHPGWTGPLCDQEARDPCLGHSCRHGTCMATGDSYVCKCAEGYGGALCDQKNDSASAC 1412
Query: 1413 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGYASCATASK 1472
SAFKCHHGQCHISD+GEPYCLCQPGFSG HC+QENPC+G++VRE IRRQK YASCATASK
Sbjct: 1413 SAFKCHHGQCHISDRGEPYCLCQPGFSGHHCEQENPCMGEIVREAIRRQKDYASCATASK 1472
Query: 1473 VPIMECRXXXXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS 1523
VPIMECR RSKRRKYVFQCTDGSSFVEEVERHLECGC ACS
Sbjct: 1473 VPIMECRGGCGSQCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRACS 1523
Score = 367 bits (931), Expect = e-100
Identities = 220/721 (30%), Positives = 349/721 (47%), Gaps = 69/721 (9%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
++CP+ C+CS VDC G GL +P +P G+ +R
Sbjct: 278 LSCPSACSCSNNIVDCRGKGLTEIPANLPE---------------------GIVEIR--- 313
Query: 92 LEDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 151
LE N + I GAF K+L+R+ ++KN++ + FQ LT L L N+I IP+
Sbjct: 314 LEQNSIKSIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIPKG 373
Query: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLR 211
F G+ ++ L L+ N I+C+ F+ L++L +L+L +N + I F + I+TL
Sbjct: 374 LFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFVPLQSIQTLH 433
Query: 212 LHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPP 271
L N CDCHL WL+D+L+ C +P L ++ ++ K++ C
Sbjct: 434 LAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRN 493
Query: 272 SCNAN---SISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAF 327
++ + CP C C IVDC + L IP++LPE ++RL N I + A G F
Sbjct: 494 RFSSECFMDLVCPEKCRCEGTIVDCSNQKLARIPSHLPEYTTDLRLNDNDISVLEATGIF 553
Query: 328 TQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXN 387
+ L++I++S N+I ++ AF G S+ L+L GN++ +
Sbjct: 554 KKLPNLRKINLSNNRIKEVREGAFDGAASVQELMLTGNQLETMHGRMFRGLSGLKTLMLR 613
Query: 388 ANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKW 447
+N I+C+ +TF L ++ LLSLYDN++ TI+ G F L S+ T++L NPF C+CH+ W
Sbjct: 614 SNLISCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHMAW 673
Query: 448 LADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPE 507
L +L+ I + RC P L I + + F C G+E+ S C + CPE
Sbjct: 674 LGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEE------SSCQLSPRCPE 727
Query: 508 KCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNN 567
+ C T+V CSN+ L +P +P+ VT+L L N + T + K+L R++ L
Sbjct: 728 QFTCVETVVRCSNRGLHALPKGMPKDVTELYLEGNHL-----TAVPKELSAFRQLTL--- 779
Query: 568 KIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAG 627
+ L+ N + + F +S L TL+L N + C+ F G
Sbjct: 780 ------------------IDLSNNSISMLTNHTFSNMSHLSTLILSYNRLRCIPVHAFNG 821
Query: 628 LSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGN 687
L S+R+L+L+ N I+++ G+F L SLS + L +NP +C+C L WL +W++ G
Sbjct: 822 LRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGI 881
Query: 688 PRCQKPFFLKEIPIQDVAIQDFTCDG----NEESSCQ--LSPRCPEQCTCMETVV---RC 738
RC P + + + F C G N + C LS C TC + V RC
Sbjct: 882 ARCSSPESMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRC 941
Query: 739 S 739
+
Sbjct: 942 T 942
>pir||T13953 MEGF5 protein - rat
dbj|BAA32461.1| (AB011531) MEGF5 [Rattus norvegicus]
Length = 1523
Score = 2879 bits (7382), Expect = 0.0
Identities = 1357/1523 (89%), Positives = 1398/1523 (91%)
Query: 1 MAPGWXXXXXXXXXXXXXXXXXXXXXXXXXXVACPTKCTCSAASVDCHGLGLRAVPRGIP 60
MAPG ACPTKCTCSAASVDCHGLGLRAVPRGIP
Sbjct: 1 MAPGRTGAGAAVRARLALALALASILSGPPAAACPTKCTCSAASVDCHGLGLRAVPRGIP 60
Query: 61 RNAERLDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
RNAERLDLDRNNITRITKMDF GLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK
Sbjct: 61 RNAERLDLDRNNITRITKMDFTGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNK 120
Query: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRAL 180
LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRG+T VKNLQLDNNHISCIEDGAFRAL
Sbjct: 121 LQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGVTGVKNLQLDNNHISCIEDGAFRAL 180
Query: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFT 240
RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRT+GQFT
Sbjct: 181 RDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTIGQFT 240
Query: 241 LCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGLME 300
LCMAPVHLRGF+VADVQKKEYVCP PHSE P+CNANS+SCPS C+CSNNIVDCRGKGL E
Sbjct: 241 LCMAPVHLRGFSVADVQKKEYVCPGPHSEAPACNANSLSCPSACSCSNNIVDCRGKGLTE 300
Query: 301 IPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSL 360
IPANLPEGIVEIRLEQNSIK+IPAGAF QYKKLKRIDISKNQISDIAPDAFQGLKSLTSL
Sbjct: 301 IPANLPEGIVEIRLEQNSIKSIPAGAFIQYKKLKRIDISKNQISDIAPDAFQGLKSLTSL 360
Query: 361 VLYGNKITEIAKGXXXXXXXXXXXXXNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK 420
VLYGNKITEI KG NANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK
Sbjct: 361 VLYGNKITEIPKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISK 420
Query: 421 GLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKS 480
GLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKS
Sbjct: 421 GLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKS 480
Query: 481 KKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLN 540
KKFRCSGSEDYR+RFSSECFMDLVCPEKCRCEGTIVDCSNQKL RIPSHLPEY TDLRLN
Sbjct: 481 KKFRCSGSEDYRNRFSSECFMDLVCPEKCRCEGTIVDCSNQKLSRIPSHLPEYTTDLRLN 540
Query: 541 DNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRV 600
DN+++VLEATGIFKKLPNLRKINLSNN+IKEVREGAFDGAA VQELMLTGNQLET+HGR+
Sbjct: 541 DNDIAVLEATGIFKKLPNLRKINLSNNRIKEVREGAFDGAAGVQELMLTGNQLETMHGRM 600
Query: 601 FRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL 660
FRGLSGLKTLMLRSNLI CV+NDTFAGLSSVRLLSLYDNRITTI+PGAFTTLVSLSTINL
Sbjct: 601 FRGLSGLKTLMLRSNLISCVNNDTFAGLSSVRLLSLYDNRITTISPGAFTTLVSLSTINL 660
Query: 661 LSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQ 720
LSNPFNCNCH+AWLG+WLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTC+GNEE+SCQ
Sbjct: 661 LSNPFNCNCHMAWLGRWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCEGNEENSCQ 720
Query: 721 LSPRCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLI 780
LSPRCPEQCTC+ETVVRCSN+GL LP+GMPKDVTELYLEGNHLTAVP+ELS R LTLI
Sbjct: 721 LSPRCPEQCTCVETVVRCSNRGLHTLPKGMPKDVTELYLEGNHLTAVPKELSTFRQLTLI 780
Query: 781 DLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPE 840
DLSNNSISMLTN+TFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPE
Sbjct: 781 DLSNNSISMLTNHTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPE 840
Query: 841 GSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPT 900
GSFNDLTSLSHLALG NPLHCDCSLRWLSEW+KAGYKEPGIARCSSPE MADRLLLTTPT
Sbjct: 841 GSFNDLTSLSHLALGINPLHCDCSLRWLSEWIKAGYKEPGIARCSSPESMADRLLLTTPT 900
Query: 901 HRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCI 960
HRFQCKGPVDINIVAKCNACLSSPCKNNGTC+QDPVE YRC CPYSYKGKDCTVPINTC+
Sbjct: 901 HRFQCKGPVDINIVAKCNACLSSPCKNNGTCSQDPVEQYRCTCPYSYKGKDCTVPINTCV 960
Query: 961 QNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVC 1020
QNPCQHGGTCHLS+SH+DGFSCSCPLGFEGQR ATCVDGINNY C
Sbjct: 961 QNPCQHGGTCHLSESHRDGFSCSCPLGFEGQRCEINPDDCEDNDCENSATCVDGINNYAC 1020
Query: 1021 ICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVA 1080
+CPPNYTGELCDEVID+CVPE+NLCQHEAKCI LDKGF CECVPGYSGKLCETDNDDCVA
Sbjct: 1021 VCPPNYTGELCDEVIDYCVPEMNLCQHEAKCISLDKGFRCECVPGYSGKLCETDNDDCVA 1080
Query: 1081 HKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQE 1140
HKCRHGAQCVD +NGYTC CPQGFSG FCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQE
Sbjct: 1081 HKCRHGAQCVDAVNGYTCICPQGFSGLFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQE 1140
Query: 1141 PTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGD 1200
PTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGD
Sbjct: 1141 PTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGD 1200
Query: 1201 NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPK 1260
NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHS DKG PK
Sbjct: 1201 NDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVMLNQTLNLVVDKGAPK 1260
Query: 1261 SLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKA 1320
SLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQG DRPLGGFHGCIHEVRINNELQDFKA
Sbjct: 1261 SLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGADRPLGGFHGCIHEVRINNELQDFKA 1320
Query: 1321 LPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG 1380
LPPQSLGVSPGCKSCTVC+HGLCRSVEKDSVVCEC PGWTGPLCDQEA+DPCLGH C HG
Sbjct: 1321 LPPQSLGVSPGCKSCTVCRHGLCRSVEKDSVVCECHPGWTGPLCDQEAQDPCLGHSCSHG 1380
Query: 1381 KCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSG 1440
CVATG SY+CKCAEGY G LCD KNDSANACSAFKCHHGQCHISD+GEPYCLCQPGFSG
Sbjct: 1381 TCVATGNSYVCKCAEGYEGPLCDQKNDSANACSAFKCHHGQCHISDRGEPYCLCQPGFSG 1440
Query: 1441 EHCQQENPCLGQVVREVIRRQKGYASCATASKVPIMECRXXXXXXXXXXTRSKRRKYVFQ 1500
HC+QENPCLG++VRE IRRQK YASCATASKVPIM CR RSKRRKYVFQ
Sbjct: 1441 NHCEQENPCLGEIVREAIRRQKDYASCATASKVPIMVCRGGCGSQCCQPIRSKRRKYVFQ 1500
Query: 1501 CTDGSSFVEEVERHLECGCLACS 1523
CTDGSSFVEEVERHLECGC CS
Sbjct: 1501 CTDGSSFVEEVERHLECGCRECS 1523
>gb|AAD25539.1|AF133270_1 (AF133270) SLIT2 [Homo sapiens]
Length = 1525
Score = 2110 bits (5406), Expect = 0.0
Identities = 968/1498 (64%), Positives = 1171/1498 (77%), Gaps = 9/1498 (0%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP +C+CS ++VDCHGL LR+VPR IPRN ERLDL+ NNITRITK DFAGL++LRVL L
Sbjct: 27 ACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQL 86
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N++S IERGAFQDLK+LERLRLN+N LQ+ PELLF T KL RLDLSENQIQ IPRKA
Sbjct: 87 MENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKA 146
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG D+KNLQLD N ISCIEDGAFRALRDLE+LTLNNNNI+R+ V SFNHMPK+RT RL
Sbjct: 147 FRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRL 206
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPS 272
HSN+LYCDCHLAWLSDWLR+R VG +T CM P HLRG NVA+VQK+E+VC S
Sbjct: 207 HSNNLYCDCHLAWLSDWLRKRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQS 266
Query: 273 CNANSIS---CPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQ 329
A S S CP+ CTCSNNIVDCRGKGL EIP NLPE I EIRLEQN+IK IP GAF+
Sbjct: 267 FMAPSCSVLHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSP 326
Query: 330 YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNAN 389
YKKL+RID+S NQIS++APDAFQGL+SL SLVLYGNKITE+ K NAN
Sbjct: 327 YKKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNAN 386
Query: 390 KINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLA 449
KINCLRV+ FQDL NLNLLSLYDNKLQTI+KG F+PL++IQT+HLAQNPF+CDCHLKWLA
Sbjct: 387 KINCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLA 446
Query: 450 DYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKC 509
DYL NPIETSGARC+SPRRLANKRI QIKSKKFRCSG+EDYRS+ S +CF DL CPEKC
Sbjct: 447 DYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYRSKLSGDCFADLACPEKC 506
Query: 510 RCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKI 569
RCEGT VDCSNQKL +IP H+P+Y +LRLN+NE +VLEATGIFKKLP LRKIN SNNKI
Sbjct: 507 RCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKI 566
Query: 570 KEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLS 629
++ EGAF+GA+ V E++LT N+LE V ++F+GL LKTLMLRSN I CV ND+F GLS
Sbjct: 567 TDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGNDSFIGLS 626
Query: 630 SVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPR 689
SVRLLSLYDN+ITT+ PGAF TL SLST+NLL+NPFNCNC+LAWLG+WLRK+RIV+GNPR
Sbjct: 627 SVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPR 686
Query: 690 CQKPFFLKEIPIQDVAIQDFTC-DGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPR 748
CQKP+FLKEIPIQDVAIQDFTC DGN+++SC RCP +CTC++TVVRCSNKGL+ LP+
Sbjct: 687 CQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPK 746
Query: 749 GMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSY 808
G+P+DVTELYL+GN T VP+ELS +HLTLIDLSNN IS L+N +FSNM+ L TLILSY
Sbjct: 747 GIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSY 806
Query: 809 NRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWL 868
NRLRCIP F+GL+SLR+L+LHGNDIS VPEG+FNDL++LSHLA+G NPL+CDC+++WL
Sbjct: 807 NRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWL 866
Query: 869 SEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNN 928
S+WVK+ YKEPGIARC+ P MAD+LLLTTP+ +F C+GPVD+NI+AKCN CLS+PCKN+
Sbjct: 867 SDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDVNILAKCNPCLSNPCKND 926
Query: 929 GTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGF 988
GTC DPV+ YRC CPY +KG+DC VPI+ CI NPC+HGGTCHL + +DGF C C GF
Sbjct: 927 GTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGF 986
Query: 989 EGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHE 1048
EG+ +TCVDGINNY C+CPP YTGELC+E +D C +LN CQH+
Sbjct: 987 EGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHD 1046
Query: 1049 AKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPF 1108
+KCI KGF C+C PGY G+ C+ D DDC +KC++GA C D +NGYTC CP+G+SG F
Sbjct: 1047 SKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLF 1106
Query: 1109 CEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSY 1168
CE PPMVL +TSPCD ++CQNGAQCIV EP C+C PG+ G +CEKL++VNF+ K+SY
Sbjct: 1107 CEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVSVNFINKESY 1166
Query: 1169 VELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVY 1228
+++ SAKVRPQ NI+LQ+ATD+D+GILLYKGD D +A+ELY+G VR YD+ S P + +Y
Sbjct: 1167 LQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIY 1226
Query: 1229 SVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGL 1288
SVET+NDG FH D G PK + L KQ + +SPLY+GG+P + +
Sbjct: 1227 SVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNV 1286
Query: 1289 SALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCKHGLCRSV 1346
++LRQ + FHGCI + IN+ELQDF+ +P Q+ G+ PGC+ C VC HG C+
Sbjct: 1287 ASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQT-GILPGCEPCHKKVCAHGTCQPS 1345
Query: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGT-SYMCKCAEGYGGDLCDNK 1405
+ CEC+ GW GPLCDQ DPCLG++C HG C+ SY CKC EG+GG LCD +
Sbjct: 1346 SQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEE 1405
Query: 1406 NDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGYA 1465
D N C A KC HG+C +S G+PYC C G++G+ C +E C G+ +R+ ++Q+GYA
Sbjct: 1406 EDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISCRGERIRDYYQKQQGYA 1465
Query: 1466 SCATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECGCLAC 1522
+C T KV +ECR RSKRRKY F+CTDGSSFV+EVE+ ++CGC C
Sbjct: 1466 ACQTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGCTRC 1523
Score = 253 bits (639), Expect = 1e-65
Identities = 140/487 (28%), Positives = 235/487 (47%), Gaps = 52/487 (10%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
+ACP KC C +VDC L +P IP+ L L+ N T
Sbjct: 500 LACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFT----------------- 542
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
V+E G F+ L QL ++ + NK+ + E F+ + + L+ N+++ +
Sbjct: 543 -------VLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQH 595
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
K F+G+ +K L L +N I+C+ + +F L + +L+L +N I+ + +F+ + + TL
Sbjct: 596 KMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTL 655
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+C+LAWL +WLR++R V C P L+ + DV +++ C ++
Sbjct: 656 NLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCD-DGNDD 714
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
SC+ S CP+ CTC + +V C KGL +P +P + E+ L+ N +P + Y
Sbjct: 715 NSCSPLS-RCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPK-ELSNY 772
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L ID+S N+IS ++ +F + L +L+L + N+
Sbjct: 773 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL------------------------SYNR 808
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ TF L++L LLSL+ N + + +G F L ++ L + NP CDC+++WL+D
Sbjct: 809 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 868
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P +A+K + SKKF C G D + C
Sbjct: 869 WVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDVNILAKCNPCLSNPCKNDGT 928
Query: 511 CEGTIVD 517
C VD
Sbjct: 929 CNSDPVD 935
>gb|AAD44759.1|AF144628_1 (AF144628) SLIT2 [Mus musculus]
Length = 1521
Score = 2107 bits (5400), Expect = 0.0
Identities = 963/1497 (64%), Positives = 1168/1497 (77%), Gaps = 9/1497 (0%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP +C+CS ++VDCHGL LR+VPR IPRN ERLDL+ NNITRITK DFAGL++LRVL L
Sbjct: 27 ACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQL 86
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N++S IERGAFQDLK+LERLRLN+N LQ+ PELLF T KL RLDLSENQIQ IPRKA
Sbjct: 87 MENRISTIERGAFQDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKA 146
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG D+KNLQLD N ISCIEDGAFRALRDLE+LTLNNNNI+R+ V SFNHMPK+RT RL
Sbjct: 147 FRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRL 206
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHS-EPP 271
HSN+LYCDCHLAWLSDWLRQR VG +T CM P HLRG NVA+VQK+E+VC S P
Sbjct: 207 HSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAP 266
Query: 272 SCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYK 331
SC+ + CP+ CTCSNNIVDCRGKGL EIP NLPE I EIRLEQNSI+ IP GAF+ YK
Sbjct: 267 SCSV--LHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIPPGAFSPYK 324
Query: 332 KLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKI 391
KL+R+D+S NQIS++APDAFQGL+SL SLVLYGNKITE+ K NANKI
Sbjct: 325 KLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKI 384
Query: 392 NCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADY 451
NCLRV+ FQDL NLNLLSLYDNKLQT++KG F+ L++IQT+HLAQNPF+CDCHLKWLADY
Sbjct: 385 NCLRVDAFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLADY 444
Query: 452 LQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRC 511
L NPIETSGARC+SPRRLANKRI QIKSKKFRCSG+EDYRS+ S +CF DL CPEKCRC
Sbjct: 445 LHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYRSKLSGDCFADLACPEKCRC 504
Query: 512 EGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKE 571
EGT VDCSNQ+L +IP H+P+Y +LRLN+NE +VLEATGIFKKLP LRKIN SNNKI +
Sbjct: 505 EGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITD 564
Query: 572 VREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSV 631
+ EGAF+GA+ V E++LT N+LE V ++F+GL LKTLMLRSN I CV ND+F GL SV
Sbjct: 565 IEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFIGLGSV 624
Query: 632 RLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQ 691
RLLSLYDN+ITT+ PGAF +L SLST+NLL+NPFNCNCHLAWLG+WLR++RIV+GNPRCQ
Sbjct: 625 RLLSLYDNQITTVAPGAFDSLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQ 684
Query: 692 KPFFLKEIPIQDVAIQDFTC-DGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGM 750
KP+FLKEIPIQDVAIQDFTC DGN+++SC RCP +CTC++TVVRCSNKGL+ LP+G+
Sbjct: 685 KPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTVVRCSNKGLKVLPKGI 744
Query: 751 PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
PKDVTELYL+GN T VP+ELS +HLTLIDLSNN IS L+N +FSNM+ L TLILSYNR
Sbjct: 745 PKDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 804
Query: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSE 870
LRCIP F+GL+SLR+L+LHGNDIS VPEG+FNDL++LSHLA+G NPL+CDC+++WLS+
Sbjct: 805 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 864
Query: 871 WVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGT 930
WVK+ YKEPGIARC+ P MAD+LLLTTP+ +F C+GPVDI I AKCN CLS+PCKN+GT
Sbjct: 865 WVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDITIQAKCNPCLSNPCKNDGT 924
Query: 931 CTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEG 990
C DPV+ YRC CPY +KG+DC VPI+ CI NPC+HGGTCHL + GF C+C GFEG
Sbjct: 925 CNNDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGENAGFWCTCADGFEG 984
Query: 991 QRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
+ +TCVDGINNY C+CPP YTGELC+E +D C +LN CQH++K
Sbjct: 985 ENCEVNIDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSK 1044
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
CI KGF C+C PGY G+ C+ D DDC +KC++GA C D +NGYTC CP+G+SG FCE
Sbjct: 1045 CILTPKGFKCDCTPGYIGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCVCPEGYSGLFCE 1104
Query: 1111 HPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVE 1170
PPMVL +TSPCD ++CQNGAQCI+ EP C+C PG+ G +CEKL++VNFV K+SY++
Sbjct: 1105 FSPPMVLPRTSPCDNFDCQNGAQCIIRINEPICQCLPGYLGEKCEKLVSVNFVNKESYLQ 1164
Query: 1171 LASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSV 1230
+ SAKVRPQ NI+LQ+ATD+D+GILLYKGD D +A+ELY+G VR YD+ S P + +YSV
Sbjct: 1165 IPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSV 1224
Query: 1231 ETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSA 1290
ET+NDG FH D G+PK + L KQ + +SPLY+GG+P +++
Sbjct: 1225 ETINDGNFHIVELLTLDSSLSLSVDGGSPKVITNLSKQSTLNFDSPLYVGGMPGKNNVAS 1284
Query: 1291 LRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCKHGLCRSVEK 1348
LRQ + FHGCI + IN+ELQDF+ +P Q+ G+ PGC+ C VC HG+C+ +
Sbjct: 1285 LRQAPGQNGTSFHGCIRNLYINSELQDFRKMPMQT-GILPGCEPCHKKVCAHGMCQPSSQ 1343
Query: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGT-SYMCKCAEGYGGDLCDNKND 1407
CEC GW GPLCDQ DPCLG++C HG C+ SY CKC EG+GG LCD + D
Sbjct: 1344 SGFTCECEEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEED 1403
Query: 1408 SANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGYASC 1467
N C KC HG+C +S G+PYC C GF+G+ C +E C G+ +R+ ++Q+GYA+C
Sbjct: 1404 LFNPCQMIKCKHGKCRLSGVGQPYCECNSGFTGDSCDREISCRGERIRDYYQKQQGYAAC 1463
Query: 1468 ATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS 1523
T KV +ECR RSKRRKY F+CTDGSSFV+EVE+ ++CGC C+
Sbjct: 1464 QTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGCARCA 1520
Score = 258 bits (652), Expect = 4e-67
Identities = 143/487 (29%), Positives = 237/487 (48%), Gaps = 52/487 (10%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
+ACP KC C +VDC L +P IP+ L L+ N T
Sbjct: 496 LACPEKCRCEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFT----------------- 538
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
V+E G F+ L QL ++ + NK+ + E F+ + + L+ N+++ +
Sbjct: 539 -------VLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQH 591
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
K F+G+ +K L L +N ISC+ + +F L + +L+L +N I+ + +F+ + + TL
Sbjct: 592 KMFKGLESLKTLMLRSNRISCVGNDSFIGLGSVRLLSLYDNQITTVAPGAFDSLHSLSTL 651
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+CHLAWL +WLR++R V C P L+ + DV +++ C ++
Sbjct: 652 NLLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCD-DGNDD 710
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
SC+ S CPS CTC + +V C KGL +P +P+ + E+ L+ N +P + Y
Sbjct: 711 NSCSPLS-RCPSECTCLDTVVRCSNKGLKVLPKGIPKDVTELYLDGNQFTLVPK-ELSNY 768
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L ID+S N+IS ++ +F + L +L+L + N+
Sbjct: 769 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL------------------------SYNR 804
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ TF L++L LLSL+ N + + +G F L ++ L + NP CDC+++WL+D
Sbjct: 805 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 864
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P +A+K + SKKF C G D + + C
Sbjct: 865 WVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDITIQAKCNPCLSNPCKNDGT 924
Query: 511 CEGTIVD 517
C VD
Sbjct: 925 CNNDPVD 931
>ref|NP_004778.1| slit (Drosophila) homolog 2 [Homo sapiens]
dbj|BAA35185.1| (AB017168) Slit-2 protein [Homo sapiens]
Length = 1529
Score = 2107 bits (5400), Expect = 0.0
Identities = 969/1504 (64%), Positives = 1173/1504 (77%), Gaps = 17/1504 (1%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP +C+CS ++VDCHGL LR+VPR IPRN ERLDL+ NNITRITK DFAGL++LRVL L
Sbjct: 27 ACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQL 86
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N++S IERGAFQDLK+LERLRLN+N LQ+ PELLF T KL RLDLSENQIQ IPRKA
Sbjct: 87 MENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKA 146
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG D+KNLQLD N ISCIEDGAFRALRDLE+LTLNNNNI+R+ V SFNHMPK+RT RL
Sbjct: 147 FRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRL 206
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHS-EPP 271
HSN+LYCDCHLAWLSDWLRQR VG +T CM P HLRG NVA+VQK+E+VC S P
Sbjct: 207 HSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAP 266
Query: 272 SCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYK 331
SC+ + CP+ CTCSNNIVDCRGKGL EIP NLPE I EIRLEQN+IK IP GAF+ YK
Sbjct: 267 SCSV--LHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYK 324
Query: 332 KLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKI 391
KL+RID+S NQIS++APDAFQGL+SL SLVLYGNKITE+ K NANKI
Sbjct: 325 KLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKI 384
Query: 392 NCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADY 451
NCLRV+ FQDL NLNLLSLYDNKLQTI+KG F+PL++IQT+HLAQNPF+CDCHLKWLADY
Sbjct: 385 NCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADY 444
Query: 452 LQDNPIETSGARCSSPRRLANKRISQIKSKKFRCS--------GSEDYRSRFSSECFMDL 503
L NPIETSGARC+SPRRLANKRI QIKSKKFRCS G+EDYRS+ S +CF DL
Sbjct: 445 LHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYRSKLSGDCFADL 504
Query: 504 VCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKIN 563
CPEKCRCEGT VDCSNQKL +IP H+P+Y +LRLN+NE +VLEATGIFKKLP LRKIN
Sbjct: 505 ACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKIN 564
Query: 564 LSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSND 623
SNNKI ++ EGAF+GA+ V E++LT N+LE V ++F+GL LKTLMLRSN I CV ND
Sbjct: 565 FSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRITCVGND 624
Query: 624 TFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRI 683
+F GLSSVRLLSLYDN+ITT+ PGAF TL SLST+NLL+NPFNCNC+LAWLG+WLRK+RI
Sbjct: 625 SFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRI 684
Query: 684 VSGNPRCQKPFFLKEIPIQDVAIQDFTCD-GNEESSCQLSPRCPEQCTCMETVVRCSNKG 742
V+GNPRCQKP+FLKEIPIQDVAIQDFTCD GN+++SC RCP +CTC++TVVRCSNKG
Sbjct: 685 VTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKG 744
Query: 743 LRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLS 802
L+ LP+G+P+DVTELYL+GN T VP+ELS +HLTLIDLSNN IS L+N +FSNM+ L
Sbjct: 745 LKVLPKGIPRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLL 804
Query: 803 TLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCD 862
TLILSYNRLRCIP F+GL+SLR+L+LHGNDIS VPEG+FNDL++LSHLA+G NPL+CD
Sbjct: 805 TLILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCD 864
Query: 863 CSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLS 922
C+++WLS+WVK+ YKEPGIARC+ P MAD+LLLTTP+ +F C+GPVD+NI+AKCN CLS
Sbjct: 865 CNMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDVNILAKCNPCLS 924
Query: 923 SPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSC 982
+PCKN+GTC DPV+ YRC CPY +KG+DC VPI+ CI NPC+HGGTCHL + +DGF C
Sbjct: 925 NPCKNDGTCNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWC 984
Query: 983 SCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPEL 1042
C GFEG+ +TCVDGINNY C+CPP YTGELC+E +D C +L
Sbjct: 985 ICADGFEGENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDL 1044
Query: 1043 NLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQ 1102
N CQH++KCI KGF C+C PGY G+ C+ D DDC +KC++GA C D +NGYTC CP+
Sbjct: 1045 NPCQHDSKCILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPE 1104
Query: 1103 GFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNF 1162
G+SG FCE PPMVL +TSPCD ++CQNGAQCIV EP C+C PG+ G +CEKL++VNF
Sbjct: 1105 GYSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVSVNF 1164
Query: 1163 VGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSS 1222
+ K+SY+++ SAKVRPQ NI+LQ+ATD+D+GILLYKGD D +A+ELY+G VR YD+ S
Sbjct: 1165 INKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSH 1224
Query: 1223 PPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGI 1282
P + +YSVET+NDG FH D G PK + L KQ + +SPLY+GG+
Sbjct: 1225 PASAIYSVETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGM 1284
Query: 1283 PTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCKH 1340
P + +++LRQ + FHGCI + IN+ELQDF+ +P Q+ G+ PGC+ C VC H
Sbjct: 1285 PGKSNVASLRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQT-GILPGCEPCHKKVCAH 1343
Query: 1341 GLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGT-SYMCKCAEGYGG 1399
G C+ + CEC+ GW GPLCDQ DPCLG++C HG C+ SY CKC EG+GG
Sbjct: 1344 GTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGG 1403
Query: 1400 DLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIR 1459
LCD + D N C A KC HG+C +S G+PYC C G++G+ C +E C G+ +R+ +
Sbjct: 1404 VLCDEEEDLFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISCRGERIRDYYQ 1463
Query: 1460 RQKGYASCATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECG 1518
+Q+GYA+C T KV +ECR RSKRRKY F+CTDGSSFV+EVE+ ++CG
Sbjct: 1464 KQQGYAACQTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCG 1523
Query: 1519 CLAC 1522
C C
Sbjct: 1524 CTRC 1527
Score = 253 bits (639), Expect = 1e-65
Identities = 140/487 (28%), Positives = 235/487 (47%), Gaps = 52/487 (10%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
+ACP KC C +VDC L +P IP+ L L+ N T
Sbjct: 504 LACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFT----------------- 546
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
V+E G F+ L QL ++ + NK+ + E F+ + + L+ N+++ +
Sbjct: 547 -------VLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQH 599
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
K F+G+ +K L L +N I+C+ + +F L + +L+L +N I+ + +F+ + + TL
Sbjct: 600 KMFKGLESLKTLMLRSNRITCVGNDSFIGLSSVRLLSLYDNQITTVAPGAFDTLHSLSTL 659
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+C+LAWL +WLR++R V C P L+ + DV +++ C ++
Sbjct: 660 NLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCD-DGNDD 718
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
SC+ S CP+ CTC + +V C KGL +P +P + E+ L+ N +P + Y
Sbjct: 719 NSCSPLS-RCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPK-ELSNY 776
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L ID+S N+IS ++ +F + L +L+L + N+
Sbjct: 777 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL------------------------SYNR 812
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ TF L++L LLSL+ N + + +G F L ++ L + NP CDC+++WL+D
Sbjct: 813 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 872
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P +A+K + SKKF C G D + C
Sbjct: 873 WVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDVNILAKCNPCLSNPCKNDGT 932
Query: 511 CEGTIVD 517
C VD
Sbjct: 933 CNSDPVD 939
>gb|AAD04309.1| (AF055585) neurogenic extracellular slit protein Slit2 [Homo sapiens]
Length = 1521
Score = 2107 bits (5399), Expect = 0.0
Identities = 965/1496 (64%), Positives = 1171/1496 (77%), Gaps = 9/1496 (0%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP +C+CS ++VDCHGL LR+VPR IPRN ERLDL+ NNITRITK DFAGL++LRVL L
Sbjct: 27 ACPAQCSCSGSTVDCHGLALRSVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRVLQL 86
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N++S IERGAFQDLK+LERLRLN+N LQ+ PELLF T KL RLDLSENQIQ IPRKA
Sbjct: 87 MENKISTIERGAFQDLKELERLRLNRNHLQLFPELLFLGTAKLYRLDLSENQIQAIPRKA 146
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG D+KNLQLD N ISCIEDGAFRALRDLE+LTLNNNNI+R+ V SFNHMPK+RT RL
Sbjct: 147 FRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRL 206
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHS-EPP 271
HSN+LYCDCHLAWLSDWLRQR VG +T CM P HLRG NVA+VQK+E+VC S P
Sbjct: 207 HSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSGHQSFMAP 266
Query: 272 SCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYK 331
SC+ + CP+ CTCSNNIVDCRGKGL EIP NLPE I EIRLEQN+IK IP GAF+ YK
Sbjct: 267 SCSV--LHCPAACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNTIKVIPPGAFSPYK 324
Query: 332 KLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKI 391
KL+RID+S NQIS++APDAFQGL+SL SLVLYGNKITE+ K NANKI
Sbjct: 325 KLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNANKI 384
Query: 392 NCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADY 451
NCLRV+ FQDL NLNLLSLYDNKLQTI+KG F+PL++IQT+HLAQNPF+CDCHLKWLADY
Sbjct: 385 NCLRVDAFQDLHNLNLLSLYDNKLQTIAKGTFSPLRAIQTMHLAQNPFICDCHLKWLADY 444
Query: 452 LQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRC 511
L NPIETSGARC+SPRRLANKRI QIKSKKFRCSG+EDYRS+ S +CF DL CPEKCRC
Sbjct: 445 LHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYRSKLSGDCFADLACPEKCRC 504
Query: 512 EGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKE 571
EGT VDCSNQKL +IP H+P+Y +LRLN+NE +VLEATGIFKKLP LRKIN SNNKI +
Sbjct: 505 EGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINFSNNKITD 564
Query: 572 VREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSV 631
+ EGAF+GA+ V E++LT N+LE V ++F+GL + LMLRSN I CV ND+F GLSSV
Sbjct: 565 IEEGAFEGASGVNEILLTSNRLENVQHKMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSV 624
Query: 632 RLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQ 691
R+LSLYDN+ITT+ PGAF TL SLST+NLL+NPFNCNC+LAWLG+WLRK+RIV+GNPRCQ
Sbjct: 625 RMLSLYDNQITTVAPGAFDTLHSLSTLNLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQ 684
Query: 692 KPFFLKEIPIQDVAIQDFTC-DGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGM 750
KP+FLKEIPIQDVAIQDFTC DGN+++SC RCP +CTC++TVVRCSNKGL+ LP+G+
Sbjct: 685 KPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPTECTCLDTVVRCSNKGLKVLPKGI 744
Query: 751 PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
P+DVTELYL+GN T VP+ELS +HLTLIDLSNN IS L+N +FSNM+ L TLILSYNR
Sbjct: 745 PRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 804
Query: 811 LRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSE 870
LRCIP F+GL+SLR+L+LHGNDIS VPEG+FNDL++LSHLA+G NPL+CDC+++WLS+
Sbjct: 805 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 864
Query: 871 WVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGT 930
WVK+ YKEPGIARC+ P MAD+LLLTTP+ +F C+GPVD+NI+AKCN CLS+PCKN+GT
Sbjct: 865 WVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDVNILAKCNPCLSNPCKNDGT 924
Query: 931 CTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEG 990
C DPV+ YRC CPY +KG+DC VPI+ CI NPC+HGGTCHL + +DGF C C GFEG
Sbjct: 925 CNSDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGEEDGFWCICADGFEG 984
Query: 991 QRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
+ +TCVDGINNY C+CPP YTGELC+E +D C +LN CQH++K
Sbjct: 985 ENCEVNVDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLNPCQHDSK 1044
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
CI KGF C+C PGY G+ C+ D DDC +KC++GA C D +NGYTC CP+G+SG FCE
Sbjct: 1045 CILTPKGFKCDCTPGYVGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCICPEGYSGLFCE 1104
Query: 1111 HPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVE 1170
PPMVL +TSPCD ++CQNGAQCIV EP C+C PG+ G +CEKL++VNF+ K+SY++
Sbjct: 1105 FSPPMVLPRTSPCDNFDCQNGAQCIVRINEPICQCLPGYQGEKCEKLVSVNFINKESYLQ 1164
Query: 1171 LASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSV 1230
+ SAKVRPQ NI+LQ+ATD+D+GILLYKGD D +A+ELY+G VR YD+ S P + +YSV
Sbjct: 1165 IPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHPASAIYSV 1224
Query: 1231 ETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSA 1290
ET+NDG FH D G PK + L KQ + +SPLY+GG+P + +++
Sbjct: 1225 ETINDGNFHIVELLALDQSLSLSVDGGNPKIITNLSKQSTLNFDSPLYVGGMPGKSNVAS 1284
Query: 1291 LRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCKHGLCRSVEK 1348
LRQ + FHGCI + IN+ELQDF+ +P Q+ G+ PGC+ C VC HG C+ +
Sbjct: 1285 LRQAPGQNGTSFHGCIRNLYINSELQDFQKVPMQT-GILPGCEPCHKKVCAHGTCQPSSQ 1343
Query: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGT-SYMCKCAEGYGGDLCDNKND 1407
CEC+ GW GPLCDQ DPCLG++C HG C+ SY CKC EG+GG LCD + D
Sbjct: 1344 AGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGVLCDEEED 1403
Query: 1408 SANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGYASC 1467
N C A KC HG+C +S G+PYC C G++G+ C +E C G+ +R+ ++Q+GYA+C
Sbjct: 1404 LFNPCQAIKCKHGKCRLSGLGQPYCECSSGYTGDSCDREISCRGERIRDYYQKQQGYAAC 1463
Query: 1468 ATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECGCLAC 1522
T KV +ECR RSKRRKY F+CTDGSSFV+EVE+ ++CGC C
Sbjct: 1464 QTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGCTRC 1519
Score = 252 bits (636), Expect = 3e-65
Identities = 140/487 (28%), Positives = 235/487 (47%), Gaps = 52/487 (10%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
+ACP KC C +VDC L +P IP+ L L+ N T
Sbjct: 496 LACPEKCRCEGTTVDCSNQKLNKIPEHIPQYTAELRLNNNEFT----------------- 538
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
V+E G F+ L QL ++ + NK+ + E F+ + + L+ N+++ +
Sbjct: 539 -------VLEATGIFKKLPQLRKINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQH 591
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
K F+G+ +NL L +N I+C+ + +F L + +L+L +N I+ + +F+ + + TL
Sbjct: 592 KMFKGLEKPQNLMLRSNRITCVGNDSFIGLSSVRMLSLYDNQITTVAPGAFDTLHSLSTL 651
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+C+LAWL +WLR++R V C P L+ + DV +++ C ++
Sbjct: 652 NLLANPFNCNCYLAWLGEWLRKKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCD-DGNDD 710
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
SC+ S CP+ CTC + +V C KGL +P +P + E+ L+ N +P + Y
Sbjct: 711 NSCSPLS-RCPTECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPK-ELSNY 768
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L ID+S N+IS ++ +F + L +L+L + N+
Sbjct: 769 KHLTLIDLSNNRISTLSNQSFSNMTQLLTLIL------------------------SYNR 804
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ TF L++L LLSL+ N + + +G F L ++ L + NP CDC+++WL+D
Sbjct: 805 LRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSD 864
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P +A+K + SKKF C G D + C
Sbjct: 865 WVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPVDVNILAKCNPCLSNPCKNDGT 924
Query: 511 CEGTIVD 517
C VD
Sbjct: 925 CNSDPVD 931
>ref|NP_003052.1| slit (Drosophila) homolog 1; slit1 [Homo sapiens]
dbj|BAA35184.1| (AB017167) Slit-1 protein [Homo sapiens]
Length = 1534
Score = 1875 bits (4804), Expect = 0.0
Identities = 872/1506 (57%), Positives = 1091/1506 (71%), Gaps = 19/1506 (1%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP CTC+ +VDCHG GL+A+P+ IPRN ERL+L+ NNITRI K DFAGLK LRVL L
Sbjct: 33 ACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQL 92
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+NQ+ +ERGAF D+K+LERLRLN+N+L +LPELLFQ+ L+RLDLSEN IQ IPRKA
Sbjct: 93 MENQIGAVERGAFDDMKELERLRLNRNQLHMLPELLFQNNQALSRLDLSENAIQAIPRKA 152
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG TD+KNL+LD N ISCIE+GAFRALR LE+LTLNNNNI+ I V+SFNHMPK+RT RL
Sbjct: 153 FRGATDLKNLRLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHS--EP 270
HSNHL+CDCHLAWLS WLRQR T+G FT C P LRG NVA+VQK E+ C
Sbjct: 213 HSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAGRV 272
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
P+C +S SCP+ CTCSN IVDCRGKGL IPANLPE + EIRLE N IK+IP GAF+ Y
Sbjct: 273 PTCTLSSGSCPAMCTCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPY 332
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
+KL+RID+S NQI++IAPDAFQGL+SL SLVLYGNKIT++ +G NANK
Sbjct: 333 RKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
INC+R + FQDLQNL+LLSLYDNK+Q+++KG F L++IQTLHLAQNPF+CDC+LKWLAD
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLAD 452
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCS--------GSEDYRSRFSSECFMD 502
+L+ NPIETSGARC+SPRRLANKRI QIKSKKFRCS G+EDY+ +SEC D
Sbjct: 453 FLRTNPIETSGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYQ--LNSECNSD 510
Query: 503 LVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKI 562
+VCP KCRCE +V+CS+ KL +IP +P+ +LRLN+NE+S+LEATG+FKKL +L+KI
Sbjct: 511 VVCPHKCRCEANVVECSSLKLTKIPERIPQSTAELRLNNNEISILEATGMFKKLTHLKKI 570
Query: 563 NLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSN 622
NLSNNK+ E+ +GAF+GAASV EL LT NQLE++ +FRGL GL+TLMLR+N I C+ N
Sbjct: 571 NLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHN 630
Query: 623 DTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRR 682
D+F GL +VRLLSLYDN+ITT++PGAF TL SLST+NLL+NPFNCNC LAWLG WLRKR+
Sbjct: 631 DSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTLNLLANPFNCNCQLAWLGGWLRKRK 690
Query: 683 IVSGNPRCQKPFFLKEIPIQDVAIQDFTCD-GNEESSCQLSPRCPEQCTCMETVVRCSNK 741
IV+GNPRCQ P FL++IP+QDVA DF C+ G EE C P+CP++C C++TVVRCSNK
Sbjct: 691 IVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEGGCLPRPQCPQECACLDTVVRCSNK 750
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
LRALP+G+PK+VTELYL+GN T VP +LS ++L L+DLSNN IS L+N +F+NMS L
Sbjct: 751 HLRALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+TLILSYN L+CIP AF GLRSLR+L+LHGNDIS++ EG F D+TSLSHLA+G NPL+C
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYC 870
Query: 862 DCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACL 921
DC LRWLS WVK GYKEPGIARC+ P+ M +LLLTTP +F+C+GP + + AKC+ CL
Sbjct: 871 DCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLAVQAKCDLCL 930
Query: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFS 981
SSPC+N GTC DP+E+YRCACP YKG+DC V +N+C PC++GGTCH + F+
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLNSCSSGPCENGGTCHAQEGEDAPFT 990
Query: 982 CSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPE 1041
CSCP GFEG CVDG+ NY C CP Y G+ C++++D C P+
Sbjct: 991 CSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPD 1050
Query: 1042 LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
LN CQHEA+C+ G CEC+PGY+G C + DDC H+C++GAQC+D +N Y+C C
Sbjct: 1051 LNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCA 1110
Query: 1102 QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVN 1161
+G+SG CE PP + SPC+ ECQNGA C+ P C+C PGF GP CEKL++VN
Sbjct: 1111 EGYSGQLCEIPPHLP-APKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKLLSVN 1169
Query: 1162 FVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLS 1221
FV +D+Y++ + P+ANI+LQV+T +DNGILLY GDND +A+ELYQGHVR+ YD S
Sbjct: 1170 FVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGS 1229
Query: 1222 SPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGG 1281
P + +YS ET+NDGQFH+ D G+P ++ K + +PLY+GG
Sbjct: 1230 YPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGG 1289
Query: 1282 IPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCK 1339
+P +A R GFHGCI + INNELQDF + GV PGC+ C C
Sbjct: 1290 MPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKP-GVVPGCEPCRKLYCL 1348
Query: 1340 HGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCV-ATGTSYMCKCAEGYG 1398
HG+C+ +C C GW G CDQ A PC GH+C HG+CV SY C+C +GY
Sbjct: 1349 HGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYS 1408
Query: 1399 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVI 1458
G LC+ A C +C HG C S +C+C PGFSGE C+QE+ C G VR+
Sbjct: 1409 GALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESECRGDPVRDFH 1468
Query: 1459 RRQKGYASCATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLEC 1517
+ Q+GYA C T + +ECR R KRRK+ F+C+DG+SF EEVE+ +C
Sbjct: 1469 QVQRGYAICQTTRPLSWVECRGSCPGQGCCQGLRLKRRKFTFECSDGTSFAEEVEKPTKC 1528
Query: 1518 GCLACS 1523
GC C+
Sbjct: 1529 GCALCA 1534
Score = 257 bits (651), Expect = 5e-67
Identities = 147/493 (29%), Positives = 241/493 (48%), Gaps = 59/493 (11%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
V CP KC C A V+C L L +P IP++ L
Sbjct: 511 VVCPHKCRCEANVVECSSLKLTKIPERIPQSTAE------------------------LR 546
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
L +N++S++E G F+ L L+++ L+ NK+ + + F+ ++ L L+ NQ++ I
Sbjct: 547 LNNNEISILEATGMFKKLTHLKKINLSNNKVSEIEDGAFEGAASVSELHLTANQLESIRS 606
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
FRG+ ++ L L NN ISCI + +F LR++ +L+L +N I+ + +F+ + + TL
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNQITTVSPGAFDTLQSLSTL 666
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+C LAWL WLR+R+ V C P LR + DV ++ C E
Sbjct: 667 NLLANPFNCNCQLAWLGGWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEE- 725
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
C CP C C + +V C K L +P +P+ + E+ L+ N +P G + +
Sbjct: 726 GGCLPRP-QCPQECACLDTVVRCSNKHLRALPKGIPKNVTELYLDGNQFTLVP-GQLSTF 783
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L+ +D+S N+IS ++ +F + LT+L+L + N
Sbjct: 784 KYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL------------------------SYNA 819
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ FQ L++L LLSL+ N + T+ +G+FA + S+ L + NP CDCHL+WL+
Sbjct: 820 LQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSS 879
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P+ + K + +KKF C G + + DL C+
Sbjct: 880 WVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGP----PTLAVQAKCDLCLSSPCQ 935
Query: 511 CEGTIVDCSNQKL 523
+GT C N L
Sbjct: 936 NQGT---CHNDPL 945
>pir||T42218 slit-1 protein homolog - rat
dbj|BAA32460.1| (AB011530) MEGF4 [Rattus norvegicus]
Length = 1531
Score = 1865 bits (4779), Expect = 0.0
Identities = 870/1506 (57%), Positives = 1084/1506 (71%), Gaps = 22/1506 (1%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP CTC+ +VDCHG GL+A+P+ IPRN ERL+L+ NNITRI K DFAGLK LRVL L
Sbjct: 33 ACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQL 92
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+NQ+ +ERGAF D+K+LERLRLN+N+LQVLPELLFQ+ L+RLDLSEN +Q +PRKA
Sbjct: 93 MENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENSLQAVPRKA 152
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG TD+KNLQLD N ISCIE+GAFRALR LE+LTLNNNNI+ I V+SFNHMPK+RT RL
Sbjct: 153 FRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPH--SEP 270
HSNHL+CDCHLAWLS WLRQR T+G FT C P LRG NVA+VQK E+ C ++
Sbjct: 213 HSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAAQV 272
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
P+C +S SCP+ C+CSN IVDCRGKGL IPANLPE + EIRLE N IK+IP GAF+ Y
Sbjct: 273 PACTLSSGSCPAMCSCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPY 332
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
+KL+RID+S NQI++IAPDAFQGL+SL SLVLYGNKIT++ +G NANK
Sbjct: 333 RKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
INC+R + FQDLQNL+LLSLYDNK+Q+++KG F L++IQTLHLAQNPF+CDC+LKWLAD
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLAD 452
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCS--------GSEDYRSRFSSECFMD 502
+L+ NPIET+GARC+SPRRLANKRI QIKSKKFRCS G+EDY +SEC D
Sbjct: 453 FLRTNPIETTGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYH--LNSECTSD 510
Query: 503 LVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKI 562
+ CP KCRCE ++V+CS KL +IP +P+ T+LRLN+NE+S+LEATG+FKKL +L+KI
Sbjct: 511 VACPHKCRCEASVVECSGLKLSKIPERIPQSTTELRLNNNEISILEATGLFKKLSHLKKI 570
Query: 563 NLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSN 622
NLSNNK+ E+ +G F+GA SV EL LT NQLE+V +FRGL GL+TLMLR+N I C+ N
Sbjct: 571 NLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSGMFRGLDGLRTLMLRNNRISCIHN 630
Query: 623 DTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRR 682
D+F GL +VRLLSLYDN ITTI+PGAF TL +LST+NLL+NPFNCNC LAWLG WLRKR+
Sbjct: 631 DSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRK 690
Query: 683 IVSGNPRCQKPFFLKEIPIQDVAIQDFTCD-GNEESSCQLSPRCPEQCTCMETVVRCSNK 741
IV+GNPRCQ P FL++IP+QDVA DF C+ G EE C P+CP++C C++TVVRCSNK
Sbjct: 691 IVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEVGCLPRPQCPQECACLDTVVRCSNK 750
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
L+ALP+G+PK+VTELYL+GN T VP +LS ++L L+DLSNN IS L+N +F+NMS L
Sbjct: 751 HLQALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+TLILSYN L+CIP AF GLRSLR+L+LHGND+S++ EG F D+TSLSHLA+G NPL+C
Sbjct: 811 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYC 870
Query: 862 DCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACL 921
DC LRWLS WVK GYKEPGIARC+ P M +LLLTTP +F+C+GP + + AKC+ CL
Sbjct: 871 DCHLRWLSSWVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSLAVQAKCDPCL 930
Query: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFS 981
SSPC+N GTC DP+E+YRC CP YKG++C V +++C NPC +GGTCH + GF+
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCTCPSGYKGRNCEVSLDSCSSNPCGNGGTCHAQEGEDAGFT 990
Query: 982 CSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPE 1041
CSCP GFEG CVDGI NY C CP YTG C++++D C P+
Sbjct: 991 CSCPSGFEGLTCGMNTDDCVKHDCVNGGVCVDGIGNYTCQCPLQYTGRACEQLVDFCSPD 1050
Query: 1042 LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
LN CQHEA+C+ +G CECVPGY+G C + DDC H+C++GAQCVD IN Y C C
Sbjct: 1051 LNPCQHEAQCVGTPEGPRCECVPGYTGDNCSKNQDDCKDHQCQNGAQCVDEINSYACLCA 1110
Query: 1102 QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVN 1161
+G+SG CE PP + C+ ECQNGA C+ P C+C PGF GP CEKL++VN
Sbjct: 1111 EGYSGQLCEIPP----APRNSCEGTECQNGANCVDQGSRPVCQCLPGFGGPECEKLLSVN 1166
Query: 1162 FVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLS 1221
FV +D+Y++ + P+ANI+LQV+T +DNGILLY GDND +A+ELYQGHVR+ YD S
Sbjct: 1167 FVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGS 1226
Query: 1222 SPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGG 1281
P + +YS ET+NDGQFH+ D G+P ++ K + +PLY+GG
Sbjct: 1227 YPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGG 1286
Query: 1282 IPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCK 1339
+P +A R FHGCI + INNELQDF + GV PGC+ C C
Sbjct: 1287 MPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTQMKP-GVVPGCEPCRKLYCL 1345
Query: 1340 HGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCV-ATGTSYMCKCAEGYG 1398
HG+C+ VC C GW G CDQ PC GH+C HGKCV +Y C+C +GY
Sbjct: 1346 HGICQPNATPGPVCHCEAGWGGLHCDQPVDGPCHGHKCVHGKCVPLDALAYSCQCQDGYS 1405
Query: 1399 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVI 1458
G LC+ A C +C HG C S +C+C PGFSGE C+QE+ C G VR+
Sbjct: 1406 GALCNQVGAVAEPCGGLQCLHGHCQASATRGAHCVCSPGFSGELCEQESECRGDPVRDFH 1465
Query: 1459 RRQKGYASCATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLEC 1517
R Q+GYA C T + +ECR R KRRK F+C+DG+SF EEVE+ +C
Sbjct: 1466 RVQRGYAICQTTRPLSWVECRGACPGQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTKC 1525
Query: 1518 GCLACS 1523
GC C+
Sbjct: 1526 GCAPCA 1531
Score = 263 bits (666), Expect = 8e-69
Identities = 151/493 (30%), Positives = 246/493 (49%), Gaps = 59/493 (11%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
VACP KC C A+ V+C GL L +P IP++ L
Sbjct: 511 VACPHKCRCEASVVECSGLKLSKIPERIPQSTTE------------------------LR 546
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
L +N++S++E G F+ L L+++ L+ NK+ + + F+ ++ L L+ NQ++ +
Sbjct: 547 LNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRS 606
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
FRG+ ++ L L NN ISCI + +F LR++ +L+L +N+I+ I +F+ + + TL
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTL 666
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+C LAWL DWLR+R+ V C P LR + DV ++ C E
Sbjct: 667 NLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEE- 725
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
C CP C C + +V C K L +P +P+ + E+ L+ N +P G + +
Sbjct: 726 VGCLPRP-QCPQECACLDTVVRCSNKHLQALPKGIPKNVTELYLDGNQFTLVP-GQLSTF 783
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L+ +D+S N+IS ++ +F + LT+L+L + N
Sbjct: 784 KYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL------------------------SYNA 819
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ FQ L++L LLSL+ N + T+ +G+FA + S+ L + NP CDCHL+WL+
Sbjct: 820 LQCIPPLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSS 879
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P + K + +KKF C G ++C L P C+
Sbjct: 880 WVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSL--AVQAKCDPCLSSP--CQ 935
Query: 511 CEGTIVDCSNQKL 523
+GT C N L
Sbjct: 936 NQGT---CHNDPL 945
>gb|AAD44758.1|AF144627_1 (AF144627) SLIT1 [Mus musculus]
Length = 1531
Score = 1854 bits (4750), Expect = 0.0
Identities = 865/1505 (57%), Positives = 1079/1505 (71%), Gaps = 22/1505 (1%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP CTC+ +VDCHG GL+A+P+ IPRN ERL+L+ NNITRI K DFAGLK LRVL L
Sbjct: 33 ACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITRIHKNDFAGLKQLRVLQL 92
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+NQ+ +ERGAF D+K+LERLRLN+N+LQVLPELLFQ+ L+RLDLSEN +Q +PRKA
Sbjct: 93 MENQIGAVERGAFDDMKELERLRLNRNQLQVLPELLFQNNQALSRLDLSENFLQAVPRKA 152
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG TD+KNLQLD N ISCIE+GAFRALR LE+LTLNNNNI+ I V+SFNHMPK+RT RL
Sbjct: 153 FRGATDLKNLQLDKNRISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP-- 270
HSNHL+CDCHLAWLS WLRQR T+G FT C P LRG NVA+VQK E+ C
Sbjct: 213 HSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKGEFSCSGQGEAAGA 272
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
P+C +S SCP+ C+CS+ IVDCRGKGL IPANLPE + EIRLE N IK+IP GAF+ Y
Sbjct: 273 PACTLSSGSCPAMCSCSSGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPY 332
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
+KL+RID+S NQI++IAPDAFQGL+SL SLVLYGNKIT++ +G NANK
Sbjct: 333 RKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
INC+R + FQDLQNL+LLSLYDNK+Q+++KG F L++IQTLHLAQNPF+CDC+LKWLAD
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLAD 452
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCS--------GSEDYRSRFSSECFMD 502
+L+ NPIET+GARC+SPRRLANKRI QIKSKKFRCS G+EDY +SEC D
Sbjct: 453 FLRTNPIETTGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYH--LNSECTSD 510
Query: 503 LVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKI 562
+ CP KCRCE ++V+CS+ KL +IP +P+ T+LRLN+NE+S+LEATG+FKKL +L+KI
Sbjct: 511 VACPHKCRCEASVVECSSLKLSKIPERIPQSTTELRLNNNEISILEATGLFKKLSHLKKI 570
Query: 563 NLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSN 622
NLSNNK+ E+ +G F+GAASV EL LT NQLE++ +FRGL GL+TLMLR+N I C+ N
Sbjct: 571 NLSNNKVSEIEDGTFEGAASVSELHLTANQLESIRSGMFRGLDGLRTLMLRNNRISCIHN 630
Query: 623 DTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRR 682
D+F GL +VRLLSLYDN ITTI+PGAF TL +LST+NLL+NPFNCNCHL+WLG WLRKR+
Sbjct: 631 DSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCHLSWLGDWLRKRK 690
Query: 683 IVSGNPRCQKPFFLKEIPIQDVAIQDFTCD-GNEESSCQLSPRCPEQCTCMETVVRCSNK 741
IV+GNPRCQ P FL++IP+QDVA DF C+ G EE C P+CP++C C++TVVRCSNK
Sbjct: 691 IVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEVGCLPRPQCPQECACLDTVVRCSNK 750
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
L+ALP+G+PK+VTELYL+GN T VP +LS ++L L+DLSNN IS L+N +F+NMS L
Sbjct: 751 HLQALPKGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 810
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+TLILSYN L+CIP AF LRSLR+L+LHGND+S++ EG F D+TSLSHLA+G NPL+C
Sbjct: 811 TTLILSYNALQCIPPLAFQRLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYC 870
Query: 862 DCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACL 921
DC LRWLS WVK GYKEPGIARC+ P M +LLLTTP +F+C+GP + + AKC+ CL
Sbjct: 871 DCRLRWLSSWVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSLAVQAKCDPCL 930
Query: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFS 981
SSPC+N GTC DP+E+YRC CP YKG+ C V ++ C NPC +GGTCH + GF+
Sbjct: 931 SSPCQNQGTCHNDPLEVYRCTCPSGYKGRHCEVSLDGCSSNPCGNGGTCHAQEGEDAGFT 990
Query: 982 CSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPE 1041
CSCP GFEG CVDG+ NY C CP YTG C++++D C P+
Sbjct: 991 CSCPSGFEGPTCGVDTDDCVKHACVNGGVCVDGVGNYTCQCPLQYTGRACEQLVDFCSPD 1050
Query: 1042 LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
+N CQHEA+C+ G CEC+ GY+G C + DDC HKC++GAQCVD +N Y C C
Sbjct: 1051 MNPCQHEAQCVGTPDGPRCECMLGYTGDNCSENQDDCKDHKCQNGAQCVDEVNSYACLCV 1110
Query: 1102 QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVN 1161
+G+SG CE PP S C+ ECQNGA C+ P C+C PGF GP CEKL++VN
Sbjct: 1111 EGYSGQLCEIPP----APRSSCEGTECQNGANCVDQGSRPVCQCLPGFGGPECEKLLSVN 1166
Query: 1162 FVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLS 1221
FV +D+Y++ + P+ANI+LQV+T +DNGILLY GDND +A+ELYQGHVR+ YD S
Sbjct: 1167 FVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGS 1226
Query: 1222 SPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGG 1281
P + +YS ET+NDGQFH+ D G+P ++ K + +PLY+GG
Sbjct: 1227 YPSSAIYSAETINDGQFHTVELVTFDQMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGG 1286
Query: 1282 IPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCK 1339
+P +A R FHGCI + INNELQDF + GV PGC+ C C
Sbjct: 1287 MPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTQMKP-GVVPGCEPCRKLYCL 1345
Query: 1340 HGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCV-ATGTSYMCKCAEGYG 1398
HG+C+ VC C GW G CDQ PC GH+C HGKCV +Y C+C +GY
Sbjct: 1346 HGICQPNATPGPVCHCEAGWGGLHCDQPVDGPCHGHKCVHGKCVPLDALAYSCQCQDGYS 1405
Query: 1399 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVI 1458
G LC+ A C +C HG C S +C+C PGFSGE C+QE+ C G VR+
Sbjct: 1406 GALCNQVGAVAEPCGGLQCLHGHCQASATKGAHCVCSPGFSGELCEQESECRGDPVRDFH 1465
Query: 1459 RRQKGYASCATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLEC 1517
R Q+GYA C T + +ECR R KRRK F+C+DG+SF EEVE+ +C
Sbjct: 1466 RVQRGYAICQTTRPLSWVECRGACPGQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTKC 1525
Query: 1518 GCLAC 1522
GC C
Sbjct: 1526 GCAQC 1530
Score = 260 bits (657), Expect = 1e-67
Identities = 150/493 (30%), Positives = 245/493 (49%), Gaps = 59/493 (11%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
VACP KC C A+ V+C L L +P IP++ L
Sbjct: 511 VACPHKCRCEASVVECSSLKLSKIPERIPQSTTE------------------------LR 546
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
L +N++S++E G F+ L L+++ L+ NK+ + + F+ ++ L L+ NQ++ I
Sbjct: 547 LNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGAASVSELHLTANQLESIRS 606
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
FRG+ ++ L L NN ISCI + +F LR++ +L+L +N+I+ I +F+ + + TL
Sbjct: 607 GMFRGLDGLRTLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTL 666
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+CHL+WL DWLR+R+ V C P LR + DV ++ C E
Sbjct: 667 NLLANPFNCNCHLSWLGDWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEE- 725
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
C CP C C + +V C K L +P +P+ + E+ L+ N +P G + +
Sbjct: 726 VGCLPRP-QCPQECACLDTVVRCSNKHLQALPKGIPKNVTELYLDGNQFTLVP-GQLSTF 783
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L+ +D+S N+IS ++ +F + LT+L+L + N
Sbjct: 784 KYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL------------------------SYNA 819
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ FQ L++L LLSL+ N + T+ +G+FA + S+ L + NP CDC L+WL+
Sbjct: 820 LQCIPPLAFQRLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCRLRWLSS 879
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P + K + +KKF C G ++C L P C+
Sbjct: 880 WVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSL--AVQAKCDPCLSSP--CQ 935
Query: 511 CEGTIVDCSNQKL 523
+GT C N L
Sbjct: 936 NQGT---CHNDPL 945
>gb|AAD25540.1|AF133730_1 (AF133730) Slit1 [Rattus norvegicus]
Length = 1530
Score = 1829 bits (4685), Expect = 0.0
Identities = 857/1506 (56%), Positives = 1073/1506 (70%), Gaps = 23/1506 (1%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP CTC+ +VDCHG GL+A+P+ IPRN ERL+L+ NNIT I K DFAGLK LRVL L
Sbjct: 33 ACPALCTCTGTTVDCHGTGLQAIPKNIPRNTERLELNGNNITWIHKNDFAGLKQLRVLQL 92
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N + +E GAF D+K+LE +LN+N+LQ+LPELLFQ+ L+RLDLSEN +Q +PRKA
Sbjct: 93 MENPIGAVEPGAFDDMKELEPFQLNRNQLQMLPELLFQNNQALSRLDLSENSLQAVPRKA 152
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG TD+KNLQLD N ISCIE+GAFRALR LE+LTLNNNNI+ I V+SFNHMPK+RT RL
Sbjct: 153 FRGATDLKNLQLDKNQISCIEEGAFRALRGLEVLTLNNNNITTIPVSSFNHMPKLRTFRL 212
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPH--SEP 270
HSNHL+CDCHLAWLS WLRQR T+G FT C P LRG NVA+VQK E+ C ++
Sbjct: 213 HSNHLFCDCHLAWLSQWLRQRPTIGLFTQCSGPASLRGLNVAEVQKSEFSCSGQGEAAQV 272
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
P+C +S SCP+ C+CSN IVDCRGKGL IPANLPE + EIRLE N IK+IP GAF+ Y
Sbjct: 273 PACTLSSGSCPAMCSCSNGIVDCRGKGLTAIPANLPETMTEIRLELNGIKSIPPGAFSPY 332
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
+KL+RID+S NQI++IAPDAFQGL+SL SLVLYGNKIT++ +G NANK
Sbjct: 333 RKLRRIDLSNNQIAEIAPDAFQGLRSLNSLVLYGNKITDLPRGVFGGLYTLQLLLLNANK 392
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
INC+R + FQDLQNL+LLSLYDNK+Q+++KG F L++IQTLHLAQNPF+CDC+LKWLAD
Sbjct: 393 INCIRPDAFQDLQNLSLLSLYDNKIQSLAKGTFTSLRAIQTLHLAQNPFICDCNLKWLAD 452
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCS--------GSEDYRSRFSSECFMD 502
+L+ NPIET+GARC+SPRRLANKRI QIKSKKFRCS G+EDY +SEC D
Sbjct: 453 FLRTNPIETTGARCASPRRLANKRIGQIKSKKFRCSAKEQYFIPGTEDYH--LNSECTSD 510
Query: 503 LVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKI 562
+ CP KCRCE ++V+CS KL +IP +P+ T+LRLN+NE+S+LEATG+FKKL +L+KI
Sbjct: 511 VACPHKCRCEASVVECSGLKLSKIPERIPQSTTELRLNNNEISILEATGLFKKLSHLKKI 570
Query: 563 NLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSN 622
NLSNNK+ E+ +G F+GA SV EL LT NQLE+V +FRGL GL +LMLR+N I C+ N
Sbjct: 571 NLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRSGMFRGLDGLWSLMLRNNRISCIHN 630
Query: 623 DTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRR 682
D+F GL +VRLLSLYDN ITTI+PGAF TL +LST+NLL+NPFNCNC LAWLG WLRKR+
Sbjct: 631 DSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTLNLLANPFNCNCQLAWLGDWLRKRK 690
Query: 683 IVSGNPRCQKPFFLKEIPIQDVAIQDFTCD-GNEESSCQLSPRCPEQCTCMETVVRCSNK 741
IV+GNPRCQ P FL++IP+QDVA DF C+ G EE C P+CP++C C++TVVRCSNK
Sbjct: 691 IVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEEVGCLPRPQCPQECACLDTVVRCSNK 750
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
L+ L +G+PK+VTELYL+GN T VP +LS ++L L+DLSNN IS L+N +F+NMS L
Sbjct: 751 HLQLL-KGIPKNVTELYLDGNQFTLVPGQLSTFKYLQLVDLSNNKISSLSNSSFTNMSQL 809
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+TLILSYN L+CIP AF GLRSLR+L+LHGND+S++ EG F D+TSLSHLA+G NPL+C
Sbjct: 810 TTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYC 869
Query: 862 DCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACL 921
DC LRWLS WVK GYKEPGIARC+ P M +LLLTTP +F+C+GP + + AKC+ CL
Sbjct: 870 DCHLRWLSSWVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPSLAVQAKCDPCL 929
Query: 922 SSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFS 981
S+PC+N GTC DP+E+YRC CP YKG++C V +++C NPC +GGTCH + GF+
Sbjct: 930 SNPCQNQGTCHNDPLEVYRCTCPSGYKGRNCEVSLDSCSSNPCGNGGTCHAQEGEDAGFT 989
Query: 982 CSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPE 1041
CSCP GFEG CVDGI NY C CP YTG C++++D C P+
Sbjct: 990 CSCPSGFEGLTCGMNTDDCVKHDCVNGGVCVDGIGNYTCQCPLQYTGRACEQLVDFCSPD 1049
Query: 1042 LNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
LN CQHEA+C+ +G CECVPGY+G C + DDC H+C++GAQCVD IN Y C C
Sbjct: 1050 LNPCQHEAQCVGTPEGPRCECVPGYTGDNCSKNQDDCKDHQCQNGAQCVDEINSYACLCA 1109
Query: 1102 QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVN 1161
+G+SG CE PP + C+ ECQNGA C+ P C+C PGF GP CEKL++VN
Sbjct: 1110 EGYSGQLCEIPP----APRNSCEGTECQNGANCVDQGSRPVCQCLPGFGGPECEKLLSVN 1165
Query: 1162 FVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLS 1221
FV +D+Y++ + P+ANI+LQV+T +DNGILLY GDND +A+ELYQGHVR+ YD S
Sbjct: 1166 FVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELYQGHVRVSYDPGS 1225
Query: 1222 SPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGG 1281
P + +YS ET+NDGQFH+ D G+P ++ K + P +GG
Sbjct: 1226 YPSSAIYSAETINDGQFHTVKLVTFDQMVNLFIDGGSPMTMDNFGKHYTLNSEGPPSVGG 1285
Query: 1282 IPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCK 1339
+P +A R FHGCI + INNELQDF + GV PGC+ C C
Sbjct: 1286 MPVDVNSAAFRLWQILNGTSFHGCIRNLYINNELQDFTKTQMKP-GVVPGCEPCRKLYCL 1344
Query: 1340 HGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCV-ATGTSYMCKCAEGYG 1398
HG+C+ VC C GW G CDQ PC GH+C HGKCV +Y C+C +GY
Sbjct: 1345 HGICQPNATPGPVCHCEAGWGGLHCDQPVDGPCHGHKCVHGKCVPLDALAYSCQCQDGYS 1404
Query: 1399 GDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVI 1458
G LC+ A C +C HG C S +C+C PGFSGE C+QE+ C G VR+
Sbjct: 1405 GALCNQVGAVAEPCGGLQCLHGHCQASVTRGAHCVCSPGFSGELCEQESECRGDPVRDFH 1464
Query: 1459 RRQKGYASCATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLEC 1517
R Q+GYA C T + +ECR R KRRK F+C+DG+SF EEVE+ +C
Sbjct: 1465 RVQRGYAICQTTRPLSWVECRGACPGQGCCQGLRLKRRKLTFECSDGTSFAEEVEKPTKC 1524
Query: 1518 GCLACS 1523
GC C+
Sbjct: 1525 GCAPCA 1530
Score = 254 bits (642), Expect = 5e-66
Identities = 148/493 (30%), Positives = 244/493 (49%), Gaps = 60/493 (12%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
VACP KC C A+ V+C GL L +P IP++ L
Sbjct: 511 VACPHKCRCEASVVECSGLKLSKIPERIPQSTTE------------------------LR 546
Query: 92 LEDNQVSVIE-RGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
L +N++S++E G F+ L L+++ L+ NK+ + + F+ ++ L L+ NQ++ +
Sbjct: 547 LNNNEISILEATGLFKKLSHLKKINLSNNKVSEIEDGTFEGATSVSELHLTANQLESVRS 606
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
FRG+ + +L L NN ISCI + +F LR++ +L+L +N+I+ I +F+ + + TL
Sbjct: 607 GMFRGLDGLWSLMLRNNRISCIHNDSFTGLRNVRLLSLYDNHITTISPGAFDTLQALSTL 666
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+C LAWL DWLR+R+ V C P LR + DV ++ C E
Sbjct: 667 NLLANPFNCNCQLAWLGDWLRKRKIVTGNPRCQNPDFLRQIPLQDVAFPDFRCEEGQEE- 725
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQY 330
C CP C C + +V C K L ++ +P+ + E+ L+ N +P G + +
Sbjct: 726 VGCLPRP-QCPQECACLDTVVRCSNKHL-QLLKGIPKNVTELYLDGNQFTLVP-GQLSTF 782
Query: 331 KKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANK 390
K L+ +D+S N+IS ++ +F + LT+L+L + N
Sbjct: 783 KYLQLVDLSNNKISSLSNSSFTNMSQLTTLIL------------------------SYNA 818
Query: 391 INCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLAD 450
+ C+ FQ L++L LLSL+ N + T+ +G+FA + S+ L + NP CDCHL+WL+
Sbjct: 819 LQCIPPLAFQGLRSLRLLSLHGNDVSTLQEGIFADVTSLSHLAIGANPLYCDCHLRWLSS 878
Query: 451 YLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCR 510
+++ E ARC+ P + K + +KKF C G + + D C+
Sbjct: 879 WVKTGYKEPGIARCAGPPEMEGKLLLTTPAKKFECQGPPS----LAVQAKCDPCLSNPCQ 934
Query: 511 CEGTIVDCSNQKL 523
+GT C N L
Sbjct: 935 NQGT---CHNDPL 944
>dbj|BAA32466.1| (AB011538) MEGF5 [Homo sapiens]
Length = 739
Score = 1517 bits (3885), Expect = 0.0
Identities = 699/739 (94%), Positives = 699/739 (94%)
Query: 785 NSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFN 844
NSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFN
Sbjct: 1 NSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFN 60
Query: 845 DLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQ 904
DLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQ
Sbjct: 61 DLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQ 120
Query: 905 CKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPC 964
CKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPC
Sbjct: 121 CKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPC 180
Query: 965 QHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPP 1024
QHGGTCHLSDSHKDGFSCSCPLGFEGQR ATCVDGINNYVCICPP
Sbjct: 181 QHGGTCHLSDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPP 240
Query: 1025 NYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCR 1084
NYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCR
Sbjct: 241 NYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCR 300
Query: 1085 HGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCR 1144
HGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCR
Sbjct: 301 HGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCR 360
Query: 1145 CPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPL 1204
CPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPL
Sbjct: 361 CPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPL 420
Query: 1205 ALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGK 1264
ALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHS DKGTPKSLGK
Sbjct: 421 ALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPKSLGK 480
Query: 1265 LQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQ 1324
LQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQ
Sbjct: 481 LQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQ 540
Query: 1325 SLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVA 1384
SLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVA
Sbjct: 541 SLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVA 600
Query: 1385 TGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
TGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ
Sbjct: 601 TGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 660
Query: 1445 QENPCLGQVVREVIRRQKGYASCATASKVPIMECRXXXXXXXXXXTRSKRRKYVFQCTDG 1504
QENPCLGQVVREVIRRQKGYASCATASKVPIMECR TRSKRRKYVFQCTDG
Sbjct: 661 QENPCLGQVVREVIRRQKGYASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDG 720
Query: 1505 SSFVEEVERHLECGCLACS 1523
SSFVEEVERHLECGCLACS
Sbjct: 721 SSFVEEVERHLECGCLACS 739
Score = 83.1 bits (202), Expect = 2e-14
Identities = 50/158 (31%), Positives = 77/158 (48%), Gaps = 9/158 (5%)
Query: 591 NQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFT 650
N + + F +S L TL+L N + C+ F GL S+R+L+L+ N I+++ G+F
Sbjct: 1 NSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFN 60
Query: 651 TLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFT 710
L SLS + L +NP +C+C L WL +W++ G RC P + + + F
Sbjct: 61 DLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQ 120
Query: 711 CDG----NEESSCQ--LSPRCPEQCTCMETVV---RCS 739
C G N + C LS C TC + V RC+
Sbjct: 121 CKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCA 158
Score = 81.1 bits (197), Expect = 8e-14
Identities = 41/126 (32%), Positives = 71/126 (55%), Gaps = 4/126 (3%)
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
N++ C+ V+ F L++L +L+L+ N + ++ +G F L S+ L L NP CDC L+WL
Sbjct: 25 NRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWL 84
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
+++++ E ARCSSP +A++ + + +F+C G D ++C L P
Sbjct: 85 SEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDI--NIVAKCNACLSSP-- 140
Query: 509 CRCEGT 514
C+ GT
Sbjct: 141 CKNNGT 146
Score = 75.7 bits (183), Expect = 4e-12
Identities = 46/153 (30%), Positives = 71/153 (46%), Gaps = 3/153 (1%)
Query: 143 NQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFN 202
N I + F ++ + L L N + CI AF LR L +LTL+ N+IS + SFN
Sbjct: 1 NSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFN 60
Query: 203 HMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYV 262
+ + L L +N L+CDC L WLS+W++ C +P + + +
Sbjct: 61 DLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQ 120
Query: 263 C--PAPHSEPPSCNA-NSISCPSPCTCSNNIVD 292
C P + CNA S C + TC+ + V+
Sbjct: 121 CKGPVDINIVAKCNACLSSPCKNNGTCTQDPVE 153
Score = 40.6 bits (93), Expect = 0.13
Identities = 23/56 (41%), Positives = 29/56 (51%)
Query: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 121
L L N + I F GL++LRVL L N +S + G+F DL L L L N L
Sbjct: 20 LILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPL 75
>gb|AAD19336.1| (AF075240) SLIT1 protein [Homo sapiens]
Length = 850
Score = 1395 bits (3571), Expect = 0.0
Identities = 702/959 (73%), Positives = 732/959 (76%), Gaps = 118/959 (12%)
Query: 574 EGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRL 633
EGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRL
Sbjct: 1 EGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRL 60
Query: 634 LSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKP 693
LSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKP
Sbjct: 61 LSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKP 120
Query: 694 FFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPKD 753
FFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPKD
Sbjct: 121 FFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPKD 180
Query: 754 VTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRC 813
VTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRC
Sbjct: 181 VTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRC 240
Query: 814 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVK 873
IPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVK
Sbjct: 241 IPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVK 300
Query: 874 AGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQ 933
AGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNA
Sbjct: 301 AGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNA-------------- 346
Query: 934 DPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRX 993
C+ +PC++ GTC
Sbjct: 347 -------------------------CLSSPCKNNGTC----------------------- 358
Query: 994 XXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIP 1053
D + Y C CP +Y G+ C I+ C+ N CQH C
Sbjct: 359 -----------------TQDPVELYRCACPYSYKGKDCTVPINTCIQ--NPCQHGGTCHL 399
Query: 1054 LDK---GFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
D GFSC C G+ G+ CE + DDC + C + A CVD IN Y C CP ++G C+
Sbjct: 400 SDSHKDGFSCSCPLGFEGQRCEINPDDCEDNDCENNATCVDGINNYVCICPPNYTGELCD 459
Query: 1111 ----HPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKD 1166
H P + L CQ+ A+CI + + +C C PG++G CE D
Sbjct: 460 EVIDHCVPELNL---------CQHEAKCIPLDKGFSCECVPGYSGKLCE-------TDND 503
Query: 1167 SYVELASAKVRPQANISLQVATDKDNGILLY--KGDNDPLALELYQGHVRLVYDSLSSPP 1224
V + K R A D NG +G + P + +VYDSLSSPP
Sbjct: 504 DCV---AHKCRHGAQ-----CVDTINGYTCTCPQGFSGPFC----EHPPPMVYDSLSSPP 551
Query: 1225 TTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPT 1284
TTVYSVETVNDGQFHS DKGTPKSLGKLQKQPAVGINSPLYLGGIPT
Sbjct: 552 TTVYSVETVNDGQFHSVELVTLNQTLNLVVDKGTPKSLGKLQKQPAVGINSPLYLGGIPT 611
Query: 1285 STGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCR 1344
STGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCR
Sbjct: 612 STGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCR 671
Query: 1345 SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDN 1404
SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDN
Sbjct: 672 SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDN 731
Query: 1405 KNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGY 1464
KNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGY
Sbjct: 732 KNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGY 791
Query: 1465 ASCATASKVPIMECRXXXXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS 1523
ASCATASKVPIMECR TRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS
Sbjct: 792 ASCATASKVPIMECRGGCGPQCCQPTRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS 850
Score = 213 bits (536), Expect = 1e-53
Identities = 119/386 (30%), Positives = 195/386 (49%), Gaps = 32/386 (8%)
Query: 129 FQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTL 188
F + L L+ NQ++ + + FRG++ +K L L +N I C+ + F L + +L+L
Sbjct: 4 FDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSL 63
Query: 189 NNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHL 248
+N I+ I +F + + T+ L SN C+CHLAWL WLR+RR V C P L
Sbjct: 64 YDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFL 123
Query: 249 RGFNVADVQKKEYVCPAPHSEPPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEG 308
+ + DV +++ C +E SC S CP CTC +V C KGL +P +P+
Sbjct: 124 KEIPIQDVAIQDFTCDG--NEESSCQL-SPRCPEQCTCMETVVRCSNKGLRALPRGMPKD 180
Query: 309 IVEIRLEQNSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKIT 368
+ E+ LE N + A+P + + L ID+S N IS + F + L++L+L
Sbjct: 181 VTELYLEGNHLTAVPR-ELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLIL------ 233
Query: 369 EIAKGXXXXXXXXXXXXXNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQS 428
+ N++ C+ V+ F L++L +L+L+ N + ++ +G F L S
Sbjct: 234 ------------------SYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTS 275
Query: 429 IQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGS 488
+ L L NP CDC L+WL+++++ E ARCSSP +A++ + + +F+C G
Sbjct: 276 LSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGP 335
Query: 489 EDYRSRFSSECFMDLVCPEKCRCEGT 514
D ++C L P C+ GT
Sbjct: 336 VDI--NIVAKCNACLSSP--CKNNGT 357
Score = 203 bits (512), Expect = 1e-50
Identities = 129/399 (32%), Positives = 191/399 (47%), Gaps = 41/399 (10%)
Query: 350 AFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKINCLRVNTFQDLQNLNLLS 409
AF G S+ L+L GN++ + +N I C+ +TF L ++ LLS
Sbjct: 3 AFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLS 62
Query: 410 LYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRR 469
LYDN++ TI+ G F L S+ T++L NPF C+CHL WL +L+ I + RC P
Sbjct: 63 LYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFF 122
Query: 470 LANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSH 529
L I + + F C G+E+ S C + CPE+C C T+V CSN+ L +P
Sbjct: 123 LKEIPIQDVAIQDFTCDGNEE------SSCQLSPRCPEQCTCMETVVRCSNKGLRALPRG 176
Query: 530 LPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLT 589
+P+ VT+L L N ++ + L +L I+LSNN I MLT
Sbjct: 177 MPKDVTELYLEGNHLTAVPRE--LSALRHLTLIDLSNNSIS----------------MLT 218
Query: 590 GNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAF 649
F +S L TL+L N + C+ F GL S+R+L+L+ N I+++ G+F
Sbjct: 219 --------NYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSF 270
Query: 650 TTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDF 709
L SLS + L +NP +C+C L WL +W++ G RC P + + + F
Sbjct: 271 NDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRF 330
Query: 710 TCDG----NEESSCQ--LSPRCPEQCTCMETVV---RCS 739
C G N + C LS C TC + V RC+
Sbjct: 331 QCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCA 369
Score = 100 bits (247), Expect = 1e-19
Identities = 70/262 (26%), Positives = 116/262 (43%), Gaps = 52/262 (19%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP +CTC V C GLRA+PRG+P++ L L+ N++T + + + + L++L ++ L
Sbjct: 152 CPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPR-ELSALRHLTLIDLS 210
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
+N +S++ F ++ L L L+ N+L+ IP AF
Sbjct: 211 NNSISMLTNYTFSNMSHLSTLILSYNRLRC------------------------IPVHAF 246
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
G+ ++ L L N IS + +G+F L TS +H L L
Sbjct: 247 NGLRSLRVLTLHGNDISSVPEGSFNDL------------------TSLSH------LALG 282
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVC--PAPHSEPP 271
+N L+CDC L WLS+W++ C +P + + + C P +
Sbjct: 283 TNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVA 342
Query: 272 SCNA-NSISCPSPCTCSNNIVD 292
CNA S C + TC+ + V+
Sbjct: 343 KCNACLSSPCKNNGTCTQDPVE 364
>gb|AAD04345.1| (AF074960) neurogenic extracellular slit protein [Mus musculus]
Length = 1025
Score = 1378 bits (3528), Expect = 0.0
Identities = 613/1024 (59%), Positives = 769/1024 (74%), Gaps = 6/1024 (0%)
Query: 505 CPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINL 564
CPEKCRCEGT VDCSNQ+L +IP H+P+Y +LRLN+NE +VLEATGIFKKLP LR IN
Sbjct: 2 CPEKCRCEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRXINF 61
Query: 565 SNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDT 624
SNNKI ++ EGAF+GA+ V E++LT N+LE V ++F+GL LKTLMLRSN I CV ND+
Sbjct: 62 SNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDS 121
Query: 625 FAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIV 684
F GL SVRLLSLYDN+ITT+ PGAF L SLST+NLL+NPFNCNCHLAWLG+WLR++RIV
Sbjct: 122 FIGLGSVRLLSLYDNQITTVAPGAFDXLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIV 181
Query: 685 SGNPRCQKPFFLKEIPIQDVAIQDFTCD-GNEESSCQLSPRCPEQCTCMETVVRCSNKGL 743
+GNPRCQKP+FLKEIPIQDVAIQDFTCD GN+++SC RCP +CTC++T VRCSNKGL
Sbjct: 182 TGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTXVRCSNKGL 241
Query: 744 RALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLST 803
+ LP+G+PKDVTELYL+GN T VP+ELS +HLTLIDLSNN IS L+N FSNM+ L T
Sbjct: 242 KVLPKGIPKDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQXFSNMTQLLT 301
Query: 804 LILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDC 863
LILSYNRLRCIP F+GL+SLR+L+LHGNDIS VPEG+FNDL++LSHLA+G NPL+CDC
Sbjct: 302 LILSYNRLRCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDC 361
Query: 864 SLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSS 923
+++WLS+WVK+ YKEPGIARC+ P MAD+LLLTTP+ +F C+GP+DI I AKCN CLS+
Sbjct: 362 NMQWLSDWVKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPMDITIQAKCNPCLSN 421
Query: 924 PCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCS 983
PCKN+GTC DPV+ YRC CPY +KG+DC VPI+ CI NPC+HGGTCHL + GF C+
Sbjct: 422 PCKNDGTCNNDPVDFYRCTCPYGFKGQDCDVPIHACISNPCKHGGTCHLKEGENAGFWCT 481
Query: 984 CPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELN 1043
C GFEG+ +TCVDGINNY C+CPP YTGELC+E +D C +LN
Sbjct: 482 CADGFEGENCEVNIDDCEDNDCENNSTCVDGINNYTCLCPPEYTGELCEEKLDFCAQDLN 541
Query: 1044 LCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQG 1103
CQH++KCI KGF C+C PGY G+ C+ D DDC +KC++GA C D +NGYTC CP+G
Sbjct: 542 PCQHDSKCILTPKGFKCDCTPGYIGEHCDIDFDDCQDNKCKNGAHCTDAVNGYTCVCPEG 601
Query: 1104 FSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLITVNFV 1163
+SG FCE PPMVL +TSPCD ++CQNGAQCI+ EP C+C PG+ G +CEKL++VNFV
Sbjct: 602 YSGLFCEFSPPMVLPRTSPCDNFDCQNGAQCIIRINEPICQCLPGYLGEKCEKLVSVNFV 661
Query: 1164 GKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSP 1223
K+SY+++ SAKVRPQ NI+LQ+ATD+D+GILLYKGD D +A+ELY+G VR YD+ S P
Sbjct: 662 NKESYLQIPSAKVRPQTNITLQIATDEDSGILLYKGDKDHIAVELYRGRVRASYDTGSHP 721
Query: 1224 PTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIP 1283
+ +YSVET+NDG FH D G+PK + L KQ + +SPLY+GG+P
Sbjct: 722 ASAIYSVETINDGNFHIVELLTLDSSLSLSVDGGSPKVITNLSKQSTLNFDSPLYVGGMP 781
Query: 1284 TSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSC--TVCKHG 1341
+++LRQ + FHGCI + IN+ELQDF+ +P Q+ G+ PGC+ C VC HG
Sbjct: 782 GKNNVASLRQAPGQNGTSFHGCIRNLYINSELQDFRKMPMQT-GILPGCEPCHKKVCAHG 840
Query: 1342 LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGT-SYMCKCAEGYGGD 1400
+C+ + CEC GW GPLCDQ DPCLG++C HG C+ SY CKC EG+GG
Sbjct: 841 MCQPSSQSGFTCECEEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLEGHGGV 900
Query: 1401 LCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRR 1460
LCD + D N C KC HG+C +S G+PYC C GF+G+ C +E C G+ +R+ ++
Sbjct: 901 LCDEEEDLFNPCQMIKCKHGKCRLSGVGQPYCECNSGFTGDSCDREISCRGERIRDYYQK 960
Query: 1461 QKGYASCATASKVPIMECRXX-XXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECGC 1519
Q+GYA+C T KV +ECR RSKRRKY F+CTDGSSFV+EVE+ ++CGC
Sbjct: 961 QQGYAACQTTKKVSRLECRGGCAGGQCCGPLRSKRRKYSFECTDGSSFVDEVEKVVKCGC 1020
Query: 1520 LACS 1523
C+
Sbjct: 1021 ARCA 1024
Score = 254 bits (643), Expect = 4e-66
Identities = 143/486 (29%), Positives = 233/486 (47%), Gaps = 52/486 (10%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP KC C +VDC L +P IP+ L L+ N T
Sbjct: 1 ACPEKCRCEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFT------------------ 42
Query: 93 EDNQVSVIER-GAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRK 151
V+E G F+ L QL + + NK+ + E F+ + + L+ N+++ + K
Sbjct: 43 ------VLEATGIFKKLPQLRXINFSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHK 96
Query: 152 AFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLR 211
F+G+ +K L L +N ISC+ + +F L + +L+L +N I+ + +F+ + + TL
Sbjct: 97 MFKGLESLKTLMLRSNRISCVGNDSFIGLGSVRLLSLYDNQITTVAPGAFDXLHSLSTLN 156
Query: 212 LHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPP 271
L +N C+CHLAWL +WLR++R V C P L+ + DV +++ C ++
Sbjct: 157 LLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCD-DGNDDN 215
Query: 272 SCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYK 331
SC+ S CPS CTC + V C KGL +P +P+ + E+ L+ N +P + YK
Sbjct: 216 SCSPLS-RCPSECTCLDTXVRCSNKGLKVLPKGIPKDVTELYLDGNQFTLVPK-ELSNYK 273
Query: 332 KLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKI 391
L ID+S N+IS ++ F + L +L+L + N++
Sbjct: 274 HLTLIDLSNNRISTLSNQXFSNMTQLLTLIL------------------------SYNRL 309
Query: 392 NCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADY 451
C+ TF L++L LLSL+ N + + +G F L ++ L + NP CDC+++WL+D+
Sbjct: 310 RCIPPRTFDGLKSLRLLSLHGNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDW 369
Query: 452 LQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRC 511
++ E ARC+ P +A+K + SKKF C G D + + C C
Sbjct: 370 VKSEYKEPGIARCAGPGEMADKLLLTTPSKKFTCQGPMDITIQAKCNPCLSNPCKNDGTC 429
Query: 512 EGTIVD 517
VD
Sbjct: 430 NNDPVD 435
Score = 246 bits (622), Expect = 1e-63
Identities = 141/460 (30%), Positives = 227/460 (48%), Gaps = 38/460 (8%)
Query: 279 SCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFTQYKKLKRID 337
+CP C C VDC + L +IP ++P+ E+RL N + A G F + +L+ I+
Sbjct: 1 ACPEKCRCEGTTVDCSNQRLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRXIN 60
Query: 338 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKINCLRVN 397
S N+I+DI AF+G + ++L N++ + +N+I+C+ +
Sbjct: 61 FSNNKITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGND 120
Query: 398 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPI 457
+F L ++ LLSLYDN++ T++ G F L S+ TL+L NPF C+CHL WL ++L+ I
Sbjct: 121 SFIGLGSVRLLSLYDNQITTVAPGAFDXLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRI 180
Query: 458 ETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVD 517
T RC P L I + + F C D + C CP +C C T V
Sbjct: 181 VTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGND-----DNSCSPLSRCPSECTCLDTXVR 235
Query: 518 CSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAF 577
CSN+ L +P +P+ VT+L L+ N+ +++ K+L N + + L
Sbjct: 236 CSNKGLKVLPKGIPKDVTELYLDGNQFTLVP-----KELSNYKHLTL------------- 277
Query: 578 DGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLY 637
+ L+ N++ T+ + F ++ L TL+L N + C+ TF GL S+RLLSL+
Sbjct: 278 --------IDLSNNRISTLSNQXFSNMTQLLTLILSYNRLRCIPPRTFDGLKSLRLLSLH 329
Query: 638 DNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLK 697
N I+ + GAF L +LS + + +NP C+C++ WL W++ G RC P +
Sbjct: 330 GNDISVVPEGAFNDLSALSHLAIGANPLYCDCNMQWLSDWVKSEYKEPGIARCAGPGEMA 389
Query: 698 EIPIQDVAIQDFTCDGNEESSCQ------LSPRCPEQCTC 731
+ + + FTC G + + Q LS C TC
Sbjct: 390 DKLLLTTPSKKFTCQGPMDITIQAKCNPCLSNPCKNDGTC 429
>gb|AAF58097.1| (AE003809) sli gene product [alt 1] [Drosophila melanogaster]
Length = 1504
Score = 1204 bits (3081), Expect = 0.0
Identities = 608/1461 (41%), Positives = 858/1461 (58%), Gaps = 69/1461 (4%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP C+C+ +VDC GL +VPR I + ERL+L NN+T I + DF L LR+L L
Sbjct: 73 CPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLT 132
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
DNQ+ IER +FQDL LERLRLN N+L+ +PE S+ L RLD+S N I + R+ F
Sbjct: 133 DNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVF 192
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
+G +++LQLDNN I+C+++ AF+ L +LEILTLNNNN++ + F + ++R LRL
Sbjct: 193 KGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLS 252
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPA-PHSEPPS 272
N CDCHL+WLS +LR + +T C +P L+G NVAD+ +E+ C P
Sbjct: 253 DNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPME 312
Query: 273 CNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
C A + SCP PC C++ IVDCR K L +P LP+ E+RLEQN I +P +F+ +++
Sbjct: 313 CGAEN-SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRR 371
Query: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKIN 392
L+RID+S N IS IA DA GLK LT+LVLYGNKI ++ G NAN+I+
Sbjct: 372 LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEIS 431
Query: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
C+R + F+DL +L+LLSLYDN +Q+++ G F ++SI+T+HLA+NPF+CDC+L+WLADYL
Sbjct: 432 CIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYL 491
Query: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCE 512
NPIETSGARC SP+R+ +RI ++ +KF+CS E R + S EC MD CP C CE
Sbjct: 492 HKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDE-LRMKLSGECRMDSDCPAMCHCE 550
Query: 513 GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEV 572
GT VDC+ + L IP +P + T+L LNDNE+ + + G+F +LP+L K+ L N++ +
Sbjct: 551 GTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGI 610
Query: 573 REGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVR 632
AF+GA+ +QEL L N+++ + ++F GL LKTL L N I CV
Sbjct: 611 EPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCV------------ 658
Query: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQK 692
PG+F L SL+++NL SNPFNCNCHLAW +WLRK+ + G RC
Sbjct: 659 ------------MPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGA 706
Query: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPK 752
P ++++ I+D+ +F C C CP CTC TVVRCS L+ +PRG+P
Sbjct: 707 PSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPA 766
Query: 753 DVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRL 811
+ +ELYLE N + + E + LR LT +DLSNN I++L+NYTF+N++ LSTLI+SYN+L
Sbjct: 767 ETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKL 826
Query: 812 RCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEW 871
+C+ HA +GL +LRVL+LHGN IS +PEGSF DL SL+H+ALG+NPL+CDC L+W S+W
Sbjct: 827 QCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDW 886
Query: 872 VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC 931
+K Y EPGIARC+ PE M D+L+L+TP+ F C+G V +I+AKCNAC PC+N C
Sbjct: 887 IKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQC 946
Query: 932 TQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQ 991
P Y+C C Y GK C I+ C NPC++ TC + + + FSC C G+ G
Sbjct: 947 VALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGR--FSCQCAPGYTGA 1004
Query: 992 R-XXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
R ATC+DG+ +Y C C P ++GE CD I C PE N C + AK
Sbjct: 1005 RCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAK 1064
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
C+ +SC+C G+ G C + DDC H C++G CVD IN Y C CP ++G +CE
Sbjct: 1065 CMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCE 1124
Query: 1111 --HPPPMVLLQTSPCDQYECQNGA--QCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKD 1166
+ M+ QTSPC +EC++G Q + CRC PG+ G CE L +++FV +
Sbjct: 1125 GHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNN 1184
Query: 1167 SYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTT 1226
S+VEL + RP+AN+++ ++ + NGIL+Y G + LA+EL+ G +R+ YD + P +T
Sbjct: 1185 SFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVST 1244
Query: 1227 VYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTST 1286
+YS E V DG++H+ D+G +S+ + + +P++LGG+P
Sbjct: 1245 MYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDP 1304
Query: 1287 GLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSV 1346
A + R L F GC+ EV IN++L DF Q ++PGC L
Sbjct: 1305 AQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQ-KITPGC--------ALLEGE 1355
Query: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLC 1402
+++ E P +E DPCL ++C G +CV + Y CKC G G C
Sbjct: 1356 QQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYC 1415
Query: 1403 DNKNDSA---NACSAFKCHHGQCH--------ISDQGEPYCLCQPGFSGEHCQQENPCLG 1451
D S +A C Q S Q Y C G + C
Sbjct: 1416 DQGEGSTEPPTVTAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCC-------- 1467
Query: 1452 QVVREVIRRQKGYASCATASK 1472
+++RR+K C+ K
Sbjct: 1468 --AAKIVRRRKVRMVCSNNRK 1486
Score = 374 bits (949), Expect = e-102
Identities = 268/984 (27%), Positives = 426/984 (43%), Gaps = 156/984 (15%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
+CP C C+ VDC L +VP +P + L L++N IT + F+ + LR + L
Sbjct: 318 SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDL 377
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N +S I A LKQ LT L L N+I+ +P
Sbjct: 378 SNNNISRIAHDALSGLKQ------------------------LTTLVLYGNKIKDLPSGV 413
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
F+G+ ++ L L+ N ISCI AFR L L +L+L +NNI + +F+ M I+T+ L
Sbjct: 414 FKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHL 473
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSE--- 269
N CDC+L WL+D+L + C +P + + ++++++ C
Sbjct: 474 AKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDELRMKL 533
Query: 270 PPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFT 328
C +S CP+ C C VDC G+GL EIP ++P E+ L N + I + G F
Sbjct: 534 SGECRMDS-DCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFG 592
Query: 329 QYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNA 388
+ L ++++ +NQ++ I P+AF+G + L L NKI EI +
Sbjct: 593 RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEI-----------------S 635
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
NK+ F L L L+LYDN++ + G F L S+ +L+LA NPF C+CHL W
Sbjct: 636 NKM-------FLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWF 688
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
A++L+ + ARC +P ++ + +I + +F+CS S S C D CP
Sbjct: 689 AEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCS------SENSEGCLGDGYCPPS 742
Query: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
C C GT+V CS +L IP +P ++L L NE+ + ++++ +LR
Sbjct: 743 CTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIH----YERIRHLR-------- 790
Query: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 628
S+ L L+ NQ+ + F L+ L TL++ N + C+ +GL
Sbjct: 791 -------------SLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL 837
Query: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP 688
+++R+LSL+ NRI+ + G+F L SL+ I L SNP C+C L W W++ + G
Sbjct: 838 NNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIA 897
Query: 689 RCQKPFFLKEIPIQDVAIQDFTCDGNEE-------SSCQLSPRCPEQCTCMETVVRCSNK 741
RC +P +K+ I F C G ++C P C Q C+
Sbjct: 898 RCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQP-CQNQAQCV--------- 947
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
ALP+ + + + G H +ID Y ++
Sbjct: 948 ---ALPQREYQCLCQPGYHGKHCE------------FMIDAC---------YGNPCRNNA 983
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+ +L R C + G R + +I N+ T + G C
Sbjct: 984 TCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQ-----NNATCID----GVESYKC 1034
Query: 862 DCSLRWLSEW--VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQC---KGPVDINIVAK 916
+C + E+ K + P C++ D TH + C G N
Sbjct: 1035 ECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHF-----TH-YSCDCQAGFHGTNCTDN 1088
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCT---------VPINTCIQNPCQHG 967
+ C + C+N GTC D + Y+C CP Y GK C + C + C+H
Sbjct: 1089 IDDCQNHMCQNGGTCV-DGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKH- 1146
Query: 968 GTCHLSDSHKDGFSCSCPLGFEGQ 991
G C ++ + C C G+ G+
Sbjct: 1147 GVCFQPNAQGSDYLCRCHPGYTGK 1170
Score = 113 bits (281), Expect = 1e-23
Identities = 73/250 (29%), Positives = 110/250 (43%), Gaps = 50/250 (20%)
Query: 724 RCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP----RELSALRHLTL 779
RCP C+C V CS++GL ++PR + DV L L+GN+LT + + L+ LR L L
Sbjct: 72 RCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQL 131
Query: 780 ---------------------------------------------IDLSNNSISMLTNYT 794
+D+SNN I+ +
Sbjct: 132 TDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRV 191
Query: 795 FSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 854
F L +L L N++ C+ HAF GL L +LTL+ N+++S+P F L L L L
Sbjct: 192 FKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRL 251
Query: 855 GTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIV 914
NP CDC L WLS ++++ + RC SP + + + F+C G + +
Sbjct: 252 SDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE-HAP 310
Query: 915 AKCNACLSSP 924
+C A S P
Sbjct: 311 MECGAENSCP 320
>gb|AAD26567.1|AF126540_1 (AF126540) slit protein [Drosophila melanogaster]
Length = 1504
Score = 1203 bits (3079), Expect = 0.0
Identities = 607/1461 (41%), Positives = 858/1461 (58%), Gaps = 69/1461 (4%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP C+C+ +VDC GL +VPR I + ERL+L NN+T I + DF L LR+L L
Sbjct: 73 CPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLT 132
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
DNQ+ IER +FQDL LERLRLN N+L+ +PE S+ L RLD+S N I + R+ F
Sbjct: 133 DNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRVF 192
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
+G +++LQLDNN I+C+++ AF+ L +LEILTLNNNN++ + F + ++R LRL
Sbjct: 193 KGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLS 252
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPA-PHSEPPS 272
N CDCHL+WLS +LR + +T C +P L+G NVAD+ +E+ C P
Sbjct: 253 DNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPME 312
Query: 273 CNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
C A + SCP PC C++ IVDCR K L +P LP+ ++RLEQN I +P +F+ +++
Sbjct: 313 CGAEN-SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRR 371
Query: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKIN 392
L+RID+S N IS IA DA GLK LT+LVLYGNKI ++ G NAN+I+
Sbjct: 372 LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEIS 431
Query: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
C+R + F+DL +L+LLSLYDN +Q+++ G F ++SI+T+HLA+NPF+CDC+L+WLADYL
Sbjct: 432 CIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYL 491
Query: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCE 512
NPIETSGARC SP+R+ +RI ++ +KF+CS E R + S EC MD CP C CE
Sbjct: 492 HKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDE-LRMKLSGECRMDSDCPAMCHCE 550
Query: 513 GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEV 572
GT VDC+ + L IP +P + T+L LNDNE+ + + G+F +LP+L K+ L N++ +
Sbjct: 551 GTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGI 610
Query: 573 REGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVR 632
AF+GA+ +QEL L N+++ + ++F GL LKTL L N I CV
Sbjct: 611 EPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCV------------ 658
Query: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQK 692
PG+F L SL+++NL SNPFNCNCHLAW +WLRK+ + G RC
Sbjct: 659 ------------MPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGA 706
Query: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPK 752
P ++++ I+D+ +F C C CP CTC TVVRCS L+ +PRG+P
Sbjct: 707 PSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPA 766
Query: 753 DVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRL 811
+ +ELYLE N + + E + LR LT +DLSNN I++L+NYTF+N++ LSTLI+SYN+L
Sbjct: 767 ETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKL 826
Query: 812 RCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEW 871
+C+ HA +GL +LRVL+LHGN IS +PEGSF DL SL+H+ALG+NPL+CDC L+W S+W
Sbjct: 827 QCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDW 886
Query: 872 VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC 931
+K Y EPGIARC+ PE M D+L+L+TP+ F C+G V +I+AKCNAC PC+N C
Sbjct: 887 IKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQC 946
Query: 932 TQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQ 991
P Y+C C Y GK C I+ C NPC++ TC + + + FSC C G+ G
Sbjct: 947 VALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGR--FSCQCAPGYTGA 1004
Query: 992 R-XXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
R ATC+DG+ +Y C C P ++GE CD I C PE N C + AK
Sbjct: 1005 RCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAK 1064
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
C+ +SC+C G+ G C + DDC H C++G CVD IN Y C CP ++G +CE
Sbjct: 1065 CMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCE 1124
Query: 1111 --HPPPMVLLQTSPCDQYECQNGA--QCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKD 1166
+ M+ QTSPC +EC++G Q + CRC PG+ G CE L +++FV +
Sbjct: 1125 GHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNN 1184
Query: 1167 SYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTT 1226
S+VEL + RP+AN+++ ++ + NGIL+Y G + LA+EL+ G +R+ YD + P +T
Sbjct: 1185 SFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVST 1244
Query: 1227 VYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTST 1286
+YS E V DG++H+ D+G +S+ + + +P++LGG+P
Sbjct: 1245 MYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDP 1304
Query: 1287 GLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSV 1346
A + R L F GC+ EV IN++L DF Q ++PGC L
Sbjct: 1305 AQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQ-KITPGC--------ALLEGE 1355
Query: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLC 1402
+++ E P +E DPCL ++C G +CV + Y CKC G G C
Sbjct: 1356 QQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYC 1415
Query: 1403 DNKNDSA---NACSAFKCHHGQCH--------ISDQGEPYCLCQPGFSGEHCQQENPCLG 1451
D S +A C Q S Q Y C G + C
Sbjct: 1416 DQGEGSTEPPTVTAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCC-------- 1467
Query: 1452 QVVREVIRRQKGYASCATASK 1472
+++RR+K C+ K
Sbjct: 1468 --AAKIVRRRKVRMVCSNNRK 1486
Score = 372 bits (944), Expect = e-101
Identities = 267/984 (27%), Positives = 426/984 (43%), Gaps = 156/984 (15%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
+CP C C+ VDC L +VP +P + + L++N IT + F+ + LR + L
Sbjct: 318 SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRRLRRIDL 377
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N +S I A LKQ LT L L N+I+ +P
Sbjct: 378 SNNNISRIAHDALSGLKQ------------------------LTTLVLYGNKIKDLPSGV 413
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
F+G+ ++ L L+ N ISCI AFR L L +L+L +NNI + +F+ M I+T+ L
Sbjct: 414 FKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHL 473
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSE--- 269
N CDC+L WL+D+L + C +P + + ++++++ C
Sbjct: 474 AKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDELRMKL 533
Query: 270 PPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFT 328
C +S CP+ C C VDC G+GL EIP ++P E+ L N + I + G F
Sbjct: 534 SGECRMDS-DCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFG 592
Query: 329 QYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNA 388
+ L ++++ +NQ++ I P+AF+G + L L NKI EI +
Sbjct: 593 RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEI-----------------S 635
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
NK+ F L L L+LYDN++ + G F L S+ +L+LA NPF C+CHL W
Sbjct: 636 NKM-------FLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWF 688
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
A++L+ + ARC +P ++ + +I + +F+CS S S C D CP
Sbjct: 689 AEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCS------SENSEGCLGDGYCPPS 742
Query: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
C C GT+V CS +L IP +P ++L L NE+ + ++++ +LR
Sbjct: 743 CTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIH----YERIRHLR-------- 790
Query: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 628
S+ L L+ NQ+ + F L+ L TL++ N + C+ +GL
Sbjct: 791 -------------SLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL 837
Query: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP 688
+++R+LSL+ NRI+ + G+F L SL+ I L SNP C+C L W W++ + G
Sbjct: 838 NNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIA 897
Query: 689 RCQKPFFLKEIPIQDVAIQDFTCDGNEE-------SSCQLSPRCPEQCTCMETVVRCSNK 741
RC +P +K+ I F C G ++C P C Q C+
Sbjct: 898 RCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQP-CQNQAQCV--------- 947
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
ALP+ + + + G H +ID Y ++
Sbjct: 948 ---ALPQREYQCLCQPGYHGKHCE------------FMIDAC---------YGNPCRNNA 983
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+ +L R C + G R + +I N+ T + G C
Sbjct: 984 TCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQ-----NNATCID----GVESYKC 1034
Query: 862 DCSLRWLSEW--VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQC---KGPVDINIVAK 916
+C + E+ K + P C++ D TH + C G N
Sbjct: 1035 ECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHF-----TH-YSCDCQAGFHGTNCTDN 1088
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCT---------VPINTCIQNPCQHG 967
+ C + C+N GTC D + Y+C CP Y GK C + C + C+H
Sbjct: 1089 IDDCQNHMCQNGGTCV-DGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKH- 1146
Query: 968 GTCHLSDSHKDGFSCSCPLGFEGQ 991
G C ++ + C C G+ G+
Sbjct: 1147 GVCFQPNAQGSDYLCRCHPGYTGK 1170
Score = 113 bits (281), Expect = 1e-23
Identities = 73/250 (29%), Positives = 110/250 (43%), Gaps = 50/250 (20%)
Query: 724 RCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP----RELSALRHLTL 779
RCP C+C V CS++GL ++PR + DV L L+GN+LT + + L+ LR L L
Sbjct: 72 RCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQL 131
Query: 780 ---------------------------------------------IDLSNNSISMLTNYT 794
+D+SNN I+ +
Sbjct: 132 TDNQIHTIERNSFQDLVSLERLRLNNNRLKAIPENFVTSSASLLRLDISNNVITTVGRRV 191
Query: 795 FSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLAL 854
F L +L L N++ C+ HAF GL L +LTL+ N+++S+P F L L L L
Sbjct: 192 FKGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRL 251
Query: 855 GTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIV 914
NP CDC L WLS ++++ + RC SP + + + F+C G + +
Sbjct: 252 SDNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTE-HAP 310
Query: 915 AKCNACLSSP 924
+C A S P
Sbjct: 311 MECGAENSCP 320
>gb|AAF58098.1| (AE003809) sli gene product [alt 2] [Drosophila melanogaster]
Length = 1480
Score = 1170 bits (2993), Expect = 0.0
Identities = 597/1461 (40%), Positives = 843/1461 (56%), Gaps = 93/1461 (6%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP C+C+ +VDC GL +VPR I + ERL+L NN+T I + DF L LR+L L
Sbjct: 73 CPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLT 132
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
DNQ+ IER +FQDL LERL D+S N I + R+ F
Sbjct: 133 DNQIHTIERNSFQDLVSLERL------------------------DISNNVITTVGRRVF 168
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
+G +++LQLDNN I+C+++ AF+ L +LEILTLNNNN++ + F + ++R LRL
Sbjct: 169 KGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLS 228
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPA-PHSEPPS 272
N CDCHL+WLS +LR + +T C +P L+G NVAD+ +E+ C P
Sbjct: 229 DNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPME 288
Query: 273 CNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
C A + SCP PC C++ IVDCR K L +P LP+ E+RLEQN I +P +F+ +++
Sbjct: 289 CGAEN-SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRR 347
Query: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKIN 392
L+RID+S N IS IA DA GLK LT+LVLYGNKI ++ G NAN+I+
Sbjct: 348 LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLQLLLLNANEIS 407
Query: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
C+R + F+DL +L+LLSLYDN +Q+++ G F ++SI+T+HLA+NPF+CDC+L+WLADYL
Sbjct: 408 CIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHLAKNPFICDCNLRWLADYL 467
Query: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCE 512
NPIETSGARC SP+R+ +RI ++ +KF+CS E R + S EC MD CP C CE
Sbjct: 468 HKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDE-LRMKLSGECRMDSDCPAMCHCE 526
Query: 513 GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEV 572
GT VDC+ + L IP +P + T+L LNDNE+ + + G+F +LP+L K+ L N++ +
Sbjct: 527 GTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGI 586
Query: 573 REGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVR 632
AF+GA+ +QEL L N+++ + ++F GL LKTL L N I CV
Sbjct: 587 EPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCV------------ 634
Query: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQK 692
PG+F L SL+++NL SNPFNCNCHLAW +WLRK+ + G RC
Sbjct: 635 ------------MPGSFEHLNSLTSLNLASNPFNCNCHLAWFAEWLRKKSLNGGAARCGA 682
Query: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPK 752
P ++++ I+D+ +F C C CP CTC TVVRCS L+ +PRG+P
Sbjct: 683 PSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVRCSRNQLKEIPRGIPA 742
Query: 753 DVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRL 811
+ +ELYLE N + + E + LR LT +DLSNN I++L+NYTF+N++ LSTLI+SYN+L
Sbjct: 743 ETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKL 802
Query: 812 RCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEW 871
+C+ HA +GL +LRVL+LHGN IS +PEGSF DL SL+H+ALG+NPL+CDC L+W S+W
Sbjct: 803 QCLQRHALSGLNNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDW 862
Query: 872 VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC 931
+K Y EPGIARC+ PE M D+L+L+TP+ F C+G V +I+AKCNAC PC+N C
Sbjct: 863 IKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQC 922
Query: 932 TQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQ 991
P Y+C C Y GK C I+ C NPC++ TC + + + FSC C G+ G
Sbjct: 923 VALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGR--FSCQCAPGYTGA 980
Query: 992 R-XXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
R ATC+DG+ +Y C C P ++GE CD I C PE N C + AK
Sbjct: 981 RCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAK 1040
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
C+ +SC+C G+ G C + DDC H C++G CVD IN Y C CP ++G +CE
Sbjct: 1041 CMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCE 1100
Query: 1111 --HPPPMVLLQTSPCDQYECQNGA--QCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKD 1166
+ M+ QTSPC +EC++G Q + CRC PG+ G CE L +++FV +
Sbjct: 1101 GHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNN 1160
Query: 1167 SYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTT 1226
S+VEL + RP+AN+++ ++ + NGIL+Y G + LA+EL+ G +R+ YD + P +T
Sbjct: 1161 SFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVST 1220
Query: 1227 VYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTST 1286
+YS E V DG++H+ D+G +S+ + + +P++LGG+P
Sbjct: 1221 MYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDP 1280
Query: 1287 GLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSV 1346
A + R L F GC+ EV IN++L DF Q ++PGC L
Sbjct: 1281 AQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQ-KITPGC--------ALLEGE 1331
Query: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLC 1402
+++ E P +E DPCL ++C G +CV + Y CKC G G C
Sbjct: 1332 QQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYC 1391
Query: 1403 DNKNDSA---NACSAFKCHHGQCH--------ISDQGEPYCLCQPGFSGEHCQQENPCLG 1451
D S +A C Q S Q Y C G + C
Sbjct: 1392 DQGEGSTEPPTVTAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCC-------- 1443
Query: 1452 QVVREVIRRQKGYASCATASK 1472
+++RR+K C+ K
Sbjct: 1444 --AAKIVRRRKVRMVCSNNRK 1462
Score = 374 bits (949), Expect = e-102
Identities = 268/984 (27%), Positives = 426/984 (43%), Gaps = 156/984 (15%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
+CP C C+ VDC L +VP +P + L L++N IT + F+ + LR + L
Sbjct: 294 SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTELRLEQNFITELPPKSFSSFRRLRRIDL 353
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N +S I A LKQ LT L L N+I+ +P
Sbjct: 354 SNNNISRIAHDALSGLKQ------------------------LTTLVLYGNKIKDLPSGV 389
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
F+G+ ++ L L+ N ISCI AFR L L +L+L +NNI + +F+ M I+T+ L
Sbjct: 390 FKGLGSLQLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSIKTVHL 449
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSE--- 269
N CDC+L WL+D+L + C +P + + ++++++ C
Sbjct: 450 AKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWDELRMKL 509
Query: 270 PPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFT 328
C +S CP+ C C VDC G+GL EIP ++P E+ L N + I + G F
Sbjct: 510 SGECRMDS-DCPAMCHCEGTTVDCTGRGLKEIPRDIPLHTTELLLNDNELGRISSDGLFG 568
Query: 329 QYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNA 388
+ L ++++ +NQ++ I P+AF+G + L L NKI EI +
Sbjct: 569 RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEI-----------------S 611
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
NK+ F L L L+LYDN++ + G F L S+ +L+LA NPF C+CHL W
Sbjct: 612 NKM-------FLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWF 664
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
A++L+ + ARC +P ++ + +I + +F+CS S S C D CP
Sbjct: 665 AEWLRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCS------SENSEGCLGDGYCPPS 718
Query: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
C C GT+V CS +L IP +P ++L L NE+ + ++++ +LR
Sbjct: 719 CTCTGTVVRCSRNQLKEIPRGIPAETSELYLESNEIEQIH----YERIRHLR-------- 766
Query: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 628
S+ L L+ NQ+ + F L+ L TL++ N + C+ +GL
Sbjct: 767 -------------SLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL 813
Query: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP 688
+++R+LSL+ NRI+ + G+F L SL+ I L SNP C+C L W W++ + G
Sbjct: 814 NNLRVLSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIA 873
Query: 689 RCQKPFFLKEIPIQDVAIQDFTCDGNEE-------SSCQLSPRCPEQCTCMETVVRCSNK 741
RC +P +K+ I F C G ++C P C Q C+
Sbjct: 874 RCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQP-CQNQAQCV--------- 923
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
ALP+ + + + G H +ID Y ++
Sbjct: 924 ---ALPQREYQCLCQPGYHGKHCE------------FMIDAC---------YGNPCRNNA 959
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+ +L R C + G R + +I N+ T + G C
Sbjct: 960 TCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQ-----NNATCID----GVESYKC 1010
Query: 862 DCSLRWLSEW--VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQC---KGPVDINIVAK 916
+C + E+ K + P C++ D TH + C G N
Sbjct: 1011 ECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHF-----TH-YSCDCQAGFHGTNCTDN 1064
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCT---------VPINTCIQNPCQHG 967
+ C + C+N GTC D + Y+C CP Y GK C + C + C+H
Sbjct: 1065 IDDCQNHMCQNGGTCV-DGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKH- 1122
Query: 968 GTCHLSDSHKDGFSCSCPLGFEGQ 991
G C ++ + C C G+ G+
Sbjct: 1123 GVCFQPNAQGSDYLCRCHPGYTGK 1146
Score = 123 bits (305), Expect = 2e-26
Identities = 73/226 (32%), Positives = 110/226 (48%), Gaps = 26/226 (11%)
Query: 724 RCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP----RELSALRHLTL 779
RCP C+C V CS++GL ++PR + DV L L+GN+LT + + L+ LR L L
Sbjct: 72 RCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQL 131
Query: 780 ---------------------IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHA 818
+D+SNN I+ + F L +L L N++ C+ HA
Sbjct: 132 TDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHA 191
Query: 819 FNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKE 878
F GL L +LTL+ N+++S+P F L L L L NP CDC L WLS ++++ +
Sbjct: 192 FKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRL 251
Query: 879 PGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSP 924
RC SP + + + F+C G + + +C A S P
Sbjct: 252 APYTRCQSPSQLKGQNVADLHDQEFKCSGLTE-HAPMECGAENSCP 296
>pir||B36665 slit protein 2 precursor - fruit fly (Drosophila melanogaster)
Length = 1469
Score = 1160 bits (2969), Expect = 0.0
Identities = 587/1450 (40%), Positives = 840/1450 (57%), Gaps = 82/1450 (5%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP C+C+ +VDC GL +VPR I + ERL+L NN+T I + DF L LR+L L
Sbjct: 73 CPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLT 132
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
DNQ+ IER +FQDL LERL D+S N I + R+ F
Sbjct: 133 DNQIHTIERNSFQDLVSLERL------------------------DISNNVITTVGRRVF 168
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
+G +++LQLDNN I+C+++ AF+ L +LEILTLNNNN++ + F + ++R LRL
Sbjct: 169 KGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLS 228
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPA-PHSEPPS 272
N CDCHL+WLS +LR + +T C +P L+G NVAD+ +E+ C P
Sbjct: 229 DNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPME 288
Query: 273 CNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
C A + SCP PC C++ IVDCR K L +P LP+ ++RLEQN I +P +F+ +++
Sbjct: 289 CGAEN-SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRR 347
Query: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKIN 392
L+RID+S N IS IA DA GLK LT+LVLYGNKI ++ G NAN+I+
Sbjct: 348 LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLRLLLLNANEIS 407
Query: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
C+R + F+DL +L+LLSLYDN +Q+++ G F ++S++T+HLA+NPF+CDC+L+WLADYL
Sbjct: 408 CIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHLAKNPFICDCNLRWLADYL 467
Query: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCE 512
NPIETSGARC SP+R+ +RI ++ +KF+CS E R + S EC MD CP C CE
Sbjct: 468 HKNPIETSGARCESPKRMHRRRIESLREEKFKCSWGE-LRMKLSGECRMDSDCPAMCHCE 526
Query: 513 GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEV 572
GT VDC+ ++L IP +P + T+L LNDNE+ + + G+F +LP+L K+ L N++ +
Sbjct: 527 GTTVDCTGRRLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGI 586
Query: 573 REGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVR 632
AF+GA+ +QEL L N+++ + ++F GL LKTL L N I CV
Sbjct: 587 EPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCV------------ 634
Query: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQK 692
PG+F L SL+++NL SNPFNCNCHLAW + +RK+ + G RC
Sbjct: 635 ------------MPGSFEHLNSLTSLNLASNPFNCNCHLAWFAECVRKKSLNGGAARCGA 682
Query: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPK 752
P ++++ I+D+ +F C C CP CTC TVV CS L+ +PRG+P
Sbjct: 683 PSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVACSRNQLKEIPRGIPA 742
Query: 753 DVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRL 811
+ +ELYLE N + + E + LR LT +DLSNN I++L+NYTF+N++ LSTLI+SYN+L
Sbjct: 743 ETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKL 802
Query: 812 RCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEW 871
+C+ HA +GL +LRV++LHGN IS +PEGSF DL SL+H+ALG+NPL+CDC L+W S+W
Sbjct: 803 QCLQRHALSGLNNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDW 862
Query: 872 VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC 931
+K Y EPGIARC+ PE M D+L+L+TP+ F C+G V +I+AKCNAC PC+N C
Sbjct: 863 IKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQC 922
Query: 932 TQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQ 991
P Y+C C Y GK C I+ C NPC++ TC + + + FSC C G+ G
Sbjct: 923 VALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGR--FSCQCAPGYTGA 980
Query: 992 R-XXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
R ATC+DG+ +Y C C P ++GE CD I C PE N C + AK
Sbjct: 981 RCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAK 1040
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
C+ +SC+C G+ G C + DDC H C++G CVD IN Y C CP ++G +CE
Sbjct: 1041 CMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCE 1100
Query: 1111 --HPPPMVLLQTSPCDQYECQNGA--QCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKD 1166
+ M+ QTSPC +EC++G Q + CRC PG+ G CE L +++FV +
Sbjct: 1101 GHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNN 1160
Query: 1167 SYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTT 1226
S+VEL + RP+AN+++ ++ + NGIL+Y G + LA+EL+ G +R+ YD + P +T
Sbjct: 1161 SFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVST 1220
Query: 1227 VYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTST 1286
+YS E V DG++H+ D+G +S+ + + +P++LGG+P
Sbjct: 1221 MYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDP 1280
Query: 1287 GLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSV 1346
A + R L F GC+ EV IN++L DF Q ++PGC L
Sbjct: 1281 AQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQ-KITPGC--------ALLEGE 1331
Query: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLC 1402
+++ E P +E DPCL ++C G +CV + Y CKC G G C
Sbjct: 1332 QQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYC 1391
Query: 1403 DNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQK 1462
D + + + S Q Y C G + C +++RR+K
Sbjct: 1392 DQAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCC----------AAKIVRRRK 1441
Query: 1463 GYASCATASK 1472
C+ K
Sbjct: 1442 VRMVCSNNRK 1451
Score = 363 bits (923), Expect = 6e-99
Identities = 263/984 (26%), Positives = 424/984 (42%), Gaps = 156/984 (15%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
+CP C C+ VDC L +VP +P + + L++N IT + F+ + LR + L
Sbjct: 294 SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRRLRRIDL 353
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N +S I A LKQ LT L L N+I+ +P
Sbjct: 354 SNNNISRIAHDALSGLKQ------------------------LTTLVLYGNKIKDLPSGV 389
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
F+G+ ++ L L+ N ISCI AFR L L +L+L +NNI + +F+ M ++T+ L
Sbjct: 390 FKGLGSLRLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHL 449
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSE--- 269
N CDC+L WL+D+L + C +P + + ++++++ C
Sbjct: 450 AKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWGELRMKL 509
Query: 270 PPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFT 328
C +S CP+ C C VDC G+ L EIP ++P E+ L N + I + G F
Sbjct: 510 SGECRMDS-DCPAMCHCEGTTVDCTGRRLKEIPRDIPLHTTELLLNDNELGRISSDGLFG 568
Query: 329 QYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNA 388
+ L ++++ +NQ++ I P+AF+G + L L NKI EI +
Sbjct: 569 RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEI-----------------S 611
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
NK+ F L L L+LYDN++ + G F L S+ +L+LA NPF C+CHL W
Sbjct: 612 NKM-------FLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWF 664
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
A+ ++ + ARC +P ++ + +I + +F+CS S S C D CP
Sbjct: 665 AECVRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCS------SENSEGCLGDGYCPPS 718
Query: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
C C GT+V CS +L IP +P ++L L NE+ + ++++ +LR
Sbjct: 719 CTCTGTVVACSRNQLKEIPRGIPAETSELYLESNEIEQIH----YERIRHLR-------- 766
Query: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 628
S+ L L+ NQ+ + F L+ L TL++ N + C+ +GL
Sbjct: 767 -------------SLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL 813
Query: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP 688
+++R++SL+ NRI+ + G+F L SL+ I L SNP C+C L W W++ + G
Sbjct: 814 NNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIA 873
Query: 689 RCQKPFFLKEIPIQDVAIQDFTCDGNEE-------SSCQLSPRCPEQCTCMETVVRCSNK 741
RC +P +K+ I F C G ++C P C Q C+
Sbjct: 874 RCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQP-CQNQAQCV--------- 923
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
ALP+ + + + G H +ID Y ++
Sbjct: 924 ---ALPQREYQCLCQPGYHGKHCE------------FMIDAC---------YGNPCRNNA 959
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+ +L R C + G R + +I N+ T + G C
Sbjct: 960 TCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQ-----NNATCID----GVESYKC 1010
Query: 862 DCSLRWLSEW--VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQC---KGPVDINIVAK 916
+C + E+ K + P C++ D TH + C G N
Sbjct: 1011 ECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHF-----TH-YSCDCQAGFHGTNCTDN 1064
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCT---------VPINTCIQNPCQHG 967
+ C + C+N GTC D + Y+C CP Y GK C + C + C+H
Sbjct: 1065 IDDCQNHMCQNGGTCV-DGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKH- 1122
Query: 968 GTCHLSDSHKDGFSCSCPLGFEGQ 991
G C ++ + C C G+ G+
Sbjct: 1123 GVCFQPNAQGSDYLCRCHPGYTGK 1146
Score = 123 bits (305), Expect = 2e-26
Identities = 73/226 (32%), Positives = 110/226 (48%), Gaps = 26/226 (11%)
Query: 724 RCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP----RELSALRHLTL 779
RCP C+C V CS++GL ++PR + DV L L+GN+LT + + L+ LR L L
Sbjct: 72 RCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQL 131
Query: 780 ---------------------IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHA 818
+D+SNN I+ + F L +L L N++ C+ HA
Sbjct: 132 TDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHA 191
Query: 819 FNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKE 878
F GL L +LTL+ N+++S+P F L L L L NP CDC L WLS ++++ +
Sbjct: 192 FKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRL 251
Query: 879 PGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSP 924
RC SP + + + F+C G + + +C A S P
Sbjct: 252 APYTRCQSPSQLKGQNVADLHDQEFKCSGLTE-HAPMECGAENSCP 296
>sp|P24014|SLIT_DROME SLIT PROTEIN PRECURSOR
pir||A36665 slit protein 1 precursor - fruit fly (Drosophila melanogaster)
emb|CAA37910.1| (X53959) slit protein [Drosophila melanogaster]
Length = 1480
Score = 1160 bits (2967), Expect = 0.0
Identities = 591/1461 (40%), Positives = 842/1461 (57%), Gaps = 93/1461 (6%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP C+C+ +VDC GL +VPR I + ERL+L NN+T I + DF L LR+L L
Sbjct: 73 CPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLT 132
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
DNQ+ IER +FQDL LERL D+S N I + R+ F
Sbjct: 133 DNQIHTIERNSFQDLVSLERL------------------------DISNNVITTVGRRVF 168
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
+G +++LQLDNN I+C+++ AF+ L +LEILTLNNNN++ + F + ++R LRL
Sbjct: 169 KGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLS 228
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPA-PHSEPPS 272
N CDCHL+WLS +LR + +T C +P L+G NVAD+ +E+ C P
Sbjct: 229 DNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPME 288
Query: 273 CNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
C A + SCP PC C++ IVDCR K L +P LP+ ++RLEQN I +P +F+ +++
Sbjct: 289 CGAEN-SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRR 347
Query: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKIN 392
L+RID+S N IS IA DA GLK LT+LVLYGNKI ++ G NAN+I+
Sbjct: 348 LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIKDLPSGVFKGLGSLRLLLLNANEIS 407
Query: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
C+R + F+DL +L+LLSLYDN +Q+++ G F ++S++T+HLA+NPF+CDC+L+WLADYL
Sbjct: 408 CIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHLAKNPFICDCNLRWLADYL 467
Query: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCE 512
NPIETSGARC SP+R+ +RI ++ +KF+CS E R + S EC MD CP C CE
Sbjct: 468 HKNPIETSGARCESPKRMHRRRIESLREEKFKCSWGE-LRMKLSGECRMDSDCPAMCHCE 526
Query: 513 GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEV 572
GT VDC+ ++L IP +P + T+L LNDNE+ + + G+F +LP+L K+ L N++ +
Sbjct: 527 GTTVDCTGRRLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGI 586
Query: 573 REGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVR 632
AF+GA+ +QEL L N+++ + ++F GL LKTL L N I CV
Sbjct: 587 EPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCV------------ 634
Query: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQK 692
PG+F L SL+++NL SNPFNCNCHLAW + +RK+ + G RC
Sbjct: 635 ------------MPGSFEHLNSLTSLNLASNPFNCNCHLAWFAECVRKKSLNGGAARCGA 682
Query: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPK 752
P ++++ I+D+ +F C C CP CTC TVV CS L+ +PRG+P
Sbjct: 683 PSKVRDVQIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVACSRNQLKEIPRGIPA 742
Query: 753 DVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRL 811
+ +ELYLE N + + E + LR LT +DLSNN I++L+NYTF+N++ LSTLI+SYN+L
Sbjct: 743 ETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKL 802
Query: 812 RCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEW 871
+C+ HA +GL +LRV++LHGN IS +PEGSF DL SL+H+ALG+NPL+CDC L+W S+W
Sbjct: 803 QCLQRHALSGLNNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDW 862
Query: 872 VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC 931
+K Y EPGIARC+ PE M D+L+L+TP+ F C+G V +I+AKCNAC PC+N C
Sbjct: 863 IKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQC 922
Query: 932 TQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQ 991
P Y+C C Y GK C I+ C NPC++ TC + + + FSC C G+ G
Sbjct: 923 VALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGR--FSCQCAPGYTGA 980
Query: 992 R-XXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
R ATC+DG+ +Y C C P ++GE CD I C PE N C + AK
Sbjct: 981 RCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAK 1040
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
C+ +SC+C G+ G C + DDC H C++G CVD IN Y C CP ++G +CE
Sbjct: 1041 CMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCE 1100
Query: 1111 --HPPPMVLLQTSPCDQYECQNGA--QCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKD 1166
+ M+ QTSPC +EC++G Q + CRC PG+ G CE L +++FV +
Sbjct: 1101 GHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNN 1160
Query: 1167 SYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTT 1226
S+VEL + RP+AN+++ ++ + NGIL+Y G + LA+EL+ G +R+ YD + P +T
Sbjct: 1161 SFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVST 1220
Query: 1227 VYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTST 1286
+YS E V DG++H+ D+G +S+ + + +P++LGG+P
Sbjct: 1221 MYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDP 1280
Query: 1287 GLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSV 1346
A + R L F GC+ EV IN++L DF Q ++PGC L
Sbjct: 1281 AQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQ-KITPGC--------ALLEGE 1331
Query: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLC 1402
+++ E P +E DPCL ++C G +CV + Y CKC G G C
Sbjct: 1332 QQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYC 1391
Query: 1403 DNKNDSA---NACSAFKCHHGQCH--------ISDQGEPYCLCQPGFSGEHCQQENPCLG 1451
D S +A C Q S Q Y C G + C
Sbjct: 1392 DQGEGSTEPPTVTAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCC-------- 1443
Query: 1452 QVVREVIRRQKGYASCATASK 1472
+++RR+K C+ K
Sbjct: 1444 --AAKIVRRRKVRMVCSNNRK 1462
Score = 363 bits (923), Expect = 6e-99
Identities = 263/984 (26%), Positives = 424/984 (42%), Gaps = 156/984 (15%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
+CP C C+ VDC L +VP +P + + L++N IT + F+ + LR + L
Sbjct: 294 SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRRLRRIDL 353
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N +S I A LKQ LT L L N+I+ +P
Sbjct: 354 SNNNISRIAHDALSGLKQ------------------------LTTLVLYGNKIKDLPSGV 389
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
F+G+ ++ L L+ N ISCI AFR L L +L+L +NNI + +F+ M ++T+ L
Sbjct: 390 FKGLGSLRLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHL 449
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSE--- 269
N CDC+L WL+D+L + C +P + + ++++++ C
Sbjct: 450 AKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCSWGELRMKL 509
Query: 270 PPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFT 328
C +S CP+ C C VDC G+ L EIP ++P E+ L N + I + G F
Sbjct: 510 SGECRMDS-DCPAMCHCEGTTVDCTGRRLKEIPRDIPLHTTELLLNDNELGRISSDGLFG 568
Query: 329 QYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNA 388
+ L ++++ +NQ++ I P+AF+G + L L NKI EI +
Sbjct: 569 RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEI-----------------S 611
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
NK+ F L L L+LYDN++ + G F L S+ +L+LA NPF C+CHL W
Sbjct: 612 NKM-------FLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWF 664
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
A+ ++ + ARC +P ++ + +I + +F+CS S S C D CP
Sbjct: 665 AECVRKKSLNGGAARCGAPSKVRDVQIKDLPHSEFKCS------SENSEGCLGDGYCPPS 718
Query: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
C C GT+V CS +L IP +P ++L L NE+ + ++++ +LR
Sbjct: 719 CTCTGTVVACSRNQLKEIPRGIPAETSELYLESNEIEQIH----YERIRHLR-------- 766
Query: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 628
S+ L L+ NQ+ + F L+ L TL++ N + C+ +GL
Sbjct: 767 -------------SLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL 813
Query: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP 688
+++R++SL+ NRI+ + G+F L SL+ I L SNP C+C L W W++ + G
Sbjct: 814 NNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIA 873
Query: 689 RCQKPFFLKEIPIQDVAIQDFTCDGNEE-------SSCQLSPRCPEQCTCMETVVRCSNK 741
RC +P +K+ I F C G ++C P C Q C+
Sbjct: 874 RCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQP-CQNQAQCV--------- 923
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
ALP+ + + + G H +ID Y ++
Sbjct: 924 ---ALPQREYQCLCQPGYHGKHCE------------FMIDAC---------YGNPCRNNA 959
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+ +L R C + G R + +I N+ T + G C
Sbjct: 960 TCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQ-----NNATCID----GVESYKC 1010
Query: 862 DCSLRWLSEW--VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQC---KGPVDINIVAK 916
+C + E+ K + P C++ D TH + C G N
Sbjct: 1011 ECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHF-----TH-YSCDCQAGFHGTNCTDN 1064
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCT---------VPINTCIQNPCQHG 967
+ C + C+N GTC D + Y+C CP Y GK C + C + C+H
Sbjct: 1065 IDDCQNHMCQNGGTCV-DGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKH- 1122
Query: 968 GTCHLSDSHKDGFSCSCPLGFEGQ 991
G C ++ + C C G+ G+
Sbjct: 1123 GVCFQPNAQGSDYLCRCHPGYTGK 1146
Score = 123 bits (305), Expect = 2e-26
Identities = 73/226 (32%), Positives = 110/226 (48%), Gaps = 26/226 (11%)
Query: 724 RCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP----RELSALRHLTL 779
RCP C+C V CS++GL ++PR + DV L L+GN+LT + + L+ LR L L
Sbjct: 72 RCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQL 131
Query: 780 ---------------------IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHA 818
+D+SNN I+ + F L +L L N++ C+ HA
Sbjct: 132 TDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHA 191
Query: 819 FNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKE 878
F GL L +LTL+ N+++S+P F L L L L NP CDC L WLS ++++ +
Sbjct: 192 FKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRL 251
Query: 879 PGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSP 924
RC SP + + + F+C G + + +C A S P
Sbjct: 252 APYTRCQSPSQLKGQNVADLHDQEFKCSGLTE-HAPMECGAENSCP 296
>prf||1704200A slit gene [Drosophila sp.]
Length = 1480
Score = 1153 bits (2950), Expect = 0.0
Identities = 589/1461 (40%), Positives = 840/1461 (57%), Gaps = 93/1461 (6%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP C+C+ +VDC GL +VPR I + ERL+L NN+T I + DF L LR+L L
Sbjct: 73 CPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQLT 132
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
DNQ+ IER +FQDL LERL D+S N I + R+ F
Sbjct: 133 DNQIHTIERNSFQDLVSLERL------------------------DISNNVITTVGRRVF 168
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
+G +++LQLDNN I+C+++ AF+ L +LEILTLNNNN++ + F + ++R LRL
Sbjct: 169 KGAQSLRSLQLDNNQITCLDEHAFKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLS 228
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPA-PHSEPPS 272
N CDCHL+WLS +LR + +T C +P L+G NVAD+ +E+ C P
Sbjct: 229 DNPFACDCHLSWLSRFLRSATRLAPYTRCQSPSQLKGQNVADLHDQEFKCSGLTEHAPME 288
Query: 273 CNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKK 332
C A + SCP PC C++ IVDCR K L +P LP+ ++RLEQN I +P +F+ +++
Sbjct: 289 CGAEN-SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRR 347
Query: 333 LKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKIN 392
L+RID+S N IS IA DA GLK LT+LVLYGNKI ++ G NAN+I+
Sbjct: 348 LRRIDLSNNNISRIAHDALSGLKQLTTLVLYGNKIFDLPSGVFKGLGSLRLLLLNANEIS 407
Query: 393 CLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYL 452
C+R + F+DL +L+LLSLYDN +Q+++ G F ++S++T+HLA+NPF+CDC+L+WLADYL
Sbjct: 408 CIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHLAKNPFICDCNLRWLADYL 467
Query: 453 QDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCE 512
NPIETSGARC SP+R+ +RI ++ +KF+C E R + S EC MD CP C CE
Sbjct: 468 HKNPIETSGARCESPKRMHRRRIESLREEKFKCEWGE-LRMKLSGECRMDSDCPAMCHCE 526
Query: 513 GTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEV 572
GT VDC+ ++L IP +P + T+L LNDNE+ + + G+F +LP+L K+ L N++ +
Sbjct: 527 GTTVDCTGRRLKEIPRDIPLHTTELLLNDNELGRISSDGLFGRLPHLVKLELKRNQLTGI 586
Query: 573 REGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVR 632
AF+GA+ +QEL L N+++ + ++F GL LKTL L N I CV
Sbjct: 587 EPNAFEGASHIQELQLGENKIKEISNKMFLGLHQLKTLNLYDNQISCV------------ 634
Query: 633 LLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQK 692
PG+F L SL+++NL SNPFNCNCHLAW + +RK+ + G RC
Sbjct: 635 ------------MPGSFEHLNSLTSLNLASNPFNCNCHLAWFAECVRKKSLNGGAARCGA 682
Query: 693 PFFLKEIPIQDVAIQDFTCDGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPRGMPK 752
P ++++ I+D+ +F C C CP CTC TVV CS L+ +PRG+P
Sbjct: 683 PSKVRDVDIKDLPHSEFKCSSENSEGCLGDGYCPPSCTCTGTVVACSRNQLKEIPRGIPA 742
Query: 753 DVTELYLEGNHLTAVPRE-LSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRL 811
+ +ELYLE N + + E + LR LT +DLSNN I++L+NYTF+N++ LSTLI+SYN+L
Sbjct: 743 ETSELYLESNEIEQIHYERIRHLRSLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKL 802
Query: 812 RCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEW 871
+C+ HA +GL +LRV++LHGN IS +PEGSF DL SL+H+ALG+NPL+CDC L+W S+W
Sbjct: 803 QCLQRHALSGLNNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDW 862
Query: 872 VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC 931
+K Y EPGIARC+ PE M D+L+L+TP+ F C+G V +I+AKCNAC PC+N C
Sbjct: 863 IKLDYVEPGIARCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQC 922
Query: 932 TQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQ 991
P Y+C C Y GK C I+ C NPC++ TC + + + FSC C G+ G
Sbjct: 923 VALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGR--FSCQCAPGYTGA 980
Query: 992 R-XXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAK 1050
R ATC+DG+ +Y C C P ++GE CD I C PE N C + AK
Sbjct: 981 RCETNIDDCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAK 1040
Query: 1051 CIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE 1110
C+ +SC+C G+ G C + DDC H C++G CVD IN Y C CP ++G +CE
Sbjct: 1041 CMDHFTHYSCDCQAGFHGTNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCE 1100
Query: 1111 --HPPPMVLLQTSPCDQYECQNGA--QCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKD 1166
+ M+ QTSPC +EC++G Q + CRC PG+ G E L +++FV +
Sbjct: 1101 GHNMISMMYPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWSEYLTSISFVHNN 1160
Query: 1167 SYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTT 1226
S+VEL + RP+AN+++ ++ + NGIL+Y G + LA+EL+ G +R+ YD + P +T
Sbjct: 1161 SFVELEPLRTRPEANVTIVFSSAEQNGILMYDGQDAHLAVELFNGPIRVSYDVGNHPVST 1220
Query: 1227 VYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTST 1286
+YS E V DG++H+ D+G +S+ + + +P++LGG+P
Sbjct: 1221 MYSFEMVADGKYHAVELLAIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDP 1280
Query: 1287 GLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSV 1346
A + R L F GC+ EV IN++L DF Q ++PGC L
Sbjct: 1281 AQQAYKNWQIRNLTSFKGCMKEVWINHKLVDFGNAQRQQ-KITPGC--------ALLEGE 1331
Query: 1347 EKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLC 1402
+++ E P +E DPCL ++C G +CV + Y CKC G G C
Sbjct: 1332 QQEEEDDEQDFMDETPHIKEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYC 1391
Query: 1403 DNKNDSA---NACSAFKCHHGQCH--------ISDQGEPYCLCQPGFSGEHCQQENPCLG 1451
D S +A C Q S Q Y C G + C
Sbjct: 1392 DQGEGSTEPPTVTAASTCRKEQVREYYTENDCRSRQPLKYAKCVGGCGNQCC-------- 1443
Query: 1452 QVVREVIRRQKGYASCATASK 1472
+++RR+K C+ K
Sbjct: 1444 --AAKIVRRRKVRMVCSNNRK 1462
Score = 361 bits (916), Expect = 4e-98
Identities = 263/984 (26%), Positives = 422/984 (42%), Gaps = 156/984 (15%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
+CP C C+ VDC L +VP +P + + L++N IT + F+ + LR + L
Sbjct: 294 SCPHPCRCADGIVDCREKSLTSVPVTLPDDTTDVRLEQNFITELPPKSFSSFRRLRRIDL 353
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N +S I A LKQ LT L L N+I +P
Sbjct: 354 SNNNISRIAHDALSGLKQ------------------------LTTLVLYGNKIFDLPSGV 389
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
F+G+ ++ L L+ N ISCI AFR L L +L+L +NNI + +F+ M ++T+ L
Sbjct: 390 FKGLGSLRLLLLNANEISCIRKDAFRDLHSLSLLSLYDNNIQSLANGTFDAMKSMKTVHL 449
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSE--- 269
N CDC+L WL+D+L + C +P + + ++++++ C
Sbjct: 450 AKNPFICDCNLRWLADYLHKNPIETSGARCESPKRMHRRRIESLREEKFKCEWGELRMKL 509
Query: 270 PPSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFT 328
C +S CP+ C C VDC G+ L EIP ++P E+ L N + I + G F
Sbjct: 510 SGECRMDS-DCPAMCHCEGTTVDCTGRRLKEIPRDIPLHTTELLLNDNELGRISSDGLFG 568
Query: 329 QYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNA 388
+ L ++++ +NQ++ I P+AF+G + L L NKI EI +
Sbjct: 569 RLPHLVKLELKRNQLTGIEPNAFEGASHIQELQLGENKIKEI-----------------S 611
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
NK+ F L L L+LYDN++ + G F L S+ +L+LA NPF C+CHL W
Sbjct: 612 NKM-------FLGLHQLKTLNLYDNQISCVMPGSFEHLNSLTSLNLASNPFNCNCHLAWF 664
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
A+ ++ + ARC +P ++ + I + +F+CS S S C D CP
Sbjct: 665 AECVRKKSLNGGAARCGAPSKVRDVDIKDLPHSEFKCS------SENSEGCLGDGYCPPS 718
Query: 509 CRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNK 568
C C GT+V CS +L IP +P ++L L NE+ + ++++ +LR
Sbjct: 719 CTCTGTVVACSRNQLKEIPRGIPAETSELYLESNEIEQIH----YERIRHLR-------- 766
Query: 569 IKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGL 628
S+ L L+ NQ+ + F L+ L TL++ N + C+ +GL
Sbjct: 767 -------------SLTRLDLSNNQITILSNYTFANLTKLSTLIISYNKLQCLQRHALSGL 813
Query: 629 SSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNP 688
+++R++SL+ NRI+ + G+F L SL+ I L SNP C+C L W W++ + G
Sbjct: 814 NNLRVVSLHGNRISMLPEGSFEDLKSLTHIALGSNPLYCDCGLKWFSDWIKLDYVEPGIA 873
Query: 689 RCQKPFFLKEIPIQDVAIQDFTCDGNEE-------SSCQLSPRCPEQCTCMETVVRCSNK 741
RC +P +K+ I F C G ++C P C Q C+
Sbjct: 874 RCAEPEQMKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQP-CQNQAQCV--------- 923
Query: 742 GLRALPRGMPKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHL 801
ALP+ + + + G H +ID Y ++
Sbjct: 924 ---ALPQREYQCLCQPGYHGKHCE------------FMIDAC---------YGNPCRNNA 959
Query: 802 STLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHC 861
+ +L R C + G R + +I N+ T + G C
Sbjct: 960 TCTVLEEGRFSCQCAPGYTGARCETNIDDCLGEIKCQ-----NNATCID----GVESYKC 1010
Query: 862 DCSLRWLSEW--VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQC---KGPVDINIVAK 916
+C + E+ K + P C++ D TH + C G N
Sbjct: 1011 ECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHF-----TH-YSCDCQAGFHGTNCTDN 1064
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCT---------VPINTCIQNPCQHG 967
+ C + C+N GTC D + Y+C CP Y GK C + C + C+H
Sbjct: 1065 IDDCQNHMCQNGGTCV-DGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNHECKH- 1122
Query: 968 GTCHLSDSHKDGFSCSCPLGFEGQ 991
G C ++ + C C G+ G+
Sbjct: 1123 GVCFQPNAQGSDYLCRCHPGYTGK 1146
Score = 123 bits (305), Expect = 2e-26
Identities = 73/226 (32%), Positives = 110/226 (48%), Gaps = 26/226 (11%)
Query: 724 RCPEQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP----RELSALRHLTL 779
RCP C+C V CS++GL ++PR + DV L L+GN+LT + + L+ LR L L
Sbjct: 72 RCPRVCSCTGLNVDCSHRGLTSVPRKISADVERLELQGNNLTVIYETDFQRLTKLRMLQL 131
Query: 780 ---------------------IDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHA 818
+D+SNN I+ + F L +L L N++ C+ HA
Sbjct: 132 TDNQIHTIERNSFQDLVSLERLDISNNVITTVGRRVFKGAQSLRSLQLDNNQITCLDEHA 191
Query: 819 FNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKE 878
F GL L +LTL+ N+++S+P F L L L L NP CDC L WLS ++++ +
Sbjct: 192 FKGLVELEILTLNNNNLTSLPHNIFGGLGRLRALRLSDNPFACDCHLSWLSRFLRSATRL 251
Query: 879 PGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSP 924
RC SP + + + F+C G + + +C A S P
Sbjct: 252 APYTRCQSPSQLKGQNVADLHDQEFKCSGLTE-HAPMECGAENSCP 296
>gb|AAD38940.2| (AF141386) SLIT-2 [Rattus norvegicus]
Length = 796
Score = 1141 bits (2918), Expect = 0.0
Identities = 538/740 (72%), Positives = 620/740 (83%), Gaps = 4/740 (0%)
Query: 33 ACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHL 92
ACP +C+CS ++VDCHGL LR VPR IPRN ERLDL+ NNITRITK DFAGL++LR+L L
Sbjct: 27 ACPAQCSCSGSTVDCHGLALRIVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRILQL 86
Query: 93 EDNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKA 152
+N++S IERGAF DLK+LERLRLN+N LQ+ PELLF T KL RLDLSENQIQ IPRKA
Sbjct: 87 MENKISTIERGAFHDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKA 146
Query: 153 FRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRL 212
FRG D+KNLQLD N ISCIEDGAFRALRDLE+LTLNNNNI+R+ V SFNHMPK+RT RL
Sbjct: 147 FRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRL 206
Query: 213 HSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPS 272
HSN+LYCDCHLAWLSDWLRQR VG +T CM P HLRG NVA+VQK+E+VC S
Sbjct: 207 HSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQS 266
Query: 273 CNANSIS---CPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQ 329
A S S CP CTCSNNIVDCRGKGL EIP NLPE I EIRLEQNSI+ IP GAF+
Sbjct: 267 FMAPSCSVLHCPIACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIPPGAFSP 326
Query: 330 YKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNAN 389
YKKL+R+D+S NQIS++APDAFQGL+SL SLVLYGNKITE+ K NAN
Sbjct: 327 YKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNAN 386
Query: 390 KINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLA 449
KINCLRV+ FQDL NLNLLSLYDNKLQT++KG F+ L++IQT+HLAQNPF+CDCHLKWLA
Sbjct: 387 KINCLRVDAFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWLA 446
Query: 450 DYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKC 509
DYL NPIETSGARC+SPRRLANKRI QIKSKKFRCSG+EDYRS+ S +CF DL CPEKC
Sbjct: 447 DYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYRSKLSGDCFADLACPEKC 506
Query: 510 RCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKI 569
RCEGT VDCSNQKL +IP H+P+Y +LRLN+NE +VLEATGIFKKLP LRKINLSNNKI
Sbjct: 507 RCEGTTVDCSNQKLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNKI 566
Query: 570 KEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLS 629
++ EGAF+GA+ V E++LT N+LE V ++F+GL LKTLMLRSN I CV ND+F GL
Sbjct: 567 TDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFTGLG 626
Query: 630 SVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGNPR 689
SVRLLSLYDN+ITT+ PGAF TL SLST+NLL+NPFNCNCHLAWLG+WLR++RIV+GNPR
Sbjct: 627 SVRLLSLYDNQITTVAPGAFGTLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIVTGNPR 686
Query: 690 CQKPFFLKEIPIQDVAIQDFTC-DGNEESSCQLSPRCPEQCTCMETVVRCSNKGLRALPR 748
CQKP+FLKEIPIQDVAIQDFTC DGN+++SC RCP +CTC++TVVRCSNKGL+ LP+
Sbjct: 687 CQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTVVRCSNKGLKVLPK 746
Query: 749 GMPKDVTELYLEGNHLTAVP 768
G+P+DVTELYL+GN T VP
Sbjct: 747 GIPRDVTELYLDGNQFTLVP 766
Score = 387 bits (983), Expect = e-106
Identities = 232/731 (31%), Positives = 350/731 (47%), Gaps = 71/731 (9%)
Query: 279 SCPSPCTCSNNIVDCRGKGLMEIPANLPE---------------------GIVEIRLEQ- 316
+CP+ C+CS + VDC G L +P N+P G+ +R+ Q
Sbjct: 27 ACPAQCSCSGSTVDCHGLALRIVPRNIPRNTERLDLNGNNITRITKTDFAGLRHLRILQL 86
Query: 317 --NSIKAIPAGAFTQYKKLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGX 374
N I I GAF K+L+R+ +++N + F G L L L N+I I +
Sbjct: 87 MENKISTIERGAFHDLKELERLRLNRNNLQLFPELLFLGTAKLYRLDLSENQIQAIPRKA 146
Query: 375 XXXXXXXXXXXXNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHL 434
+ N+I+C+ F+ L++L +L+L +N + +S F + ++T L
Sbjct: 147 FRGAVDIKNLQLDYNQISCIEDGAFRALRDLEVLTLNNNNITRLSVASFNHMPKLRTFRL 206
Query: 435 AQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSR 494
N CDCHL WL+D+L+ P +C P L +++++ ++F CS E+
Sbjct: 207 HSNNLYCDCHLAWLSDWLRQRPRVGLYTQCMGPSHLRGHNVAEVQKREFVCSDEEEGHQS 266
Query: 495 FSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFK 554
F + L CP C C IVDC + L IP++LPE +T++RL N + V+ G F
Sbjct: 267 FMAPSCSVLHCPIACTCSNNIVDCRGKGLTEIPTNLPETITEIRLEQNSIRVIPP-GAFS 325
Query: 555 KLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRS 614
LR+++LSNN+I E+ AF G S+ L+L GN++ + +F GL L+ L+L +
Sbjct: 326 PYKKLRRLDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLFSLQLLLLNA 385
Query: 615 NLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWL 674
N I C+ D F L ++ LLSLYDN++ T+ G F+ L ++ T++L NPF C+CHL WL
Sbjct: 386 NKINCLRVDAFQDLHNLNLLSLYDNKLQTVAKGTFSALRAIQTMHLAQNPFICDCHLKWL 445
Query: 675 GKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQLSP------RCPEQ 728
+L I + RC P L I + + F C G E+ +LS CPE+
Sbjct: 446 ADYLHTNPIETSGARCTSPRRLANKRIGQIKSKKFRCSGTEDYRSKLSGDCFADLACPEK 505
Query: 729 CTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRE--LSALRHLTLIDLSNNS 786
C C T V CSN+ L +P +P+ EL L N T + L L I+LSNN
Sbjct: 506 CRCEGTTVDCSNQKLNKIPDHIPQYTAELRLNNNEFTVLEATGIFKKLPQLRKINLSNNK 565
Query: 787 IS----------------MLTNYTFSNMSH--------LSTLILSYNRLRCIPVHAFNGL 822
I+ +LT+ N+ H L TL+L NR+ C+ +F GL
Sbjct: 566 ITDIEEGAFEGASGVNEILLTSNRLENVQHKMFKGLESLKTLMLRSNRISCVGNDSFTGL 625
Query: 823 RSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIA 882
S+R+L+L+ N I++V G+F L SLS L L NP +C+C L WL EW++ G
Sbjct: 626 GSVRLLSLYDNQITTVAPGAFGTLHSLSTLNLLANPFNCNCHLAWLGEWLRRKRIVTGNP 685
Query: 883 RCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSS--------PCKNNGT---- 930
RC P + + + F C D N + + C S C N G
Sbjct: 686 RCQKPYFLKEIPIQDVAIQDFTCDDGNDDNSCSPLSRCPSECTCLDTVVRCSNKGLKVLP 745
Query: 931 --CTQDPVELY 939
+D ELY
Sbjct: 746 KGIPRDVTELY 756
Score = 170 bits (427), Expect = 9e-41
Identities = 91/297 (30%), Positives = 148/297 (49%), Gaps = 27/297 (9%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
+ACP KC C +VDC L +P IP+ L L+ N T
Sbjct: 500 LACPEKCRCEGTTVDCSNQKLNKIPDHIPQYTAELRLNNNEFT----------------- 542
Query: 92 LEDNQVSVIER-GAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
V+E G F+ L QL ++ L+ NK+ + E F+ + + L+ N+++ +
Sbjct: 543 -------VLEATGIFKKLPQLRKINLSNNKITDIEEGAFEGASGVNEILLTSNRLENVQH 595
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
K F+G+ +K L L +N ISC+ + +F L + +L+L +N I+ + +F + + TL
Sbjct: 596 KMFKGLESLKTLMLRSNRISCVGNDSFTGLGSVRLLSLYDNQITTVAPGAFGTLHSLSTL 655
Query: 211 RLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEP 270
L +N C+CHLAWL +WLR++R V C P L+ + DV +++ C + +
Sbjct: 656 NLLANPFNCNCHLAWLGEWLRRKRIVTGNPRCQKPYFLKEIPIQDVAIQDFTCDDGNDDN 715
Query: 271 PSCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAF 327
SC+ S CPS CTC + +V C KGL +P +P + E+ L+ N +P F
Sbjct: 716 -SCSPLS-RCPSECTCLDTVVRCSNKGLKVLPKGIPRDVTELYLDGNQFTLVPEFPF 770
>emb|CAA93668.2| (Z69792) Similarity to Drosophila EGF-like protein slit (PIR Acc. No.
A31640), contains similarity to Pfam domain: PF00008
(EGF-like domain), Score=136.1, E-value=2e-37, N=7;
PF00054 (Laminin G domain), Score=75.1, E-value=9.7e-21,
N=1; PF00560 (Leucin>
emb|CAB63434.1| (AL022270) Similarity to Drosophila EGF-like protein slit (PIR Acc.
No. A31640), contains similarity to Pfam domain: PF00008
(EGF-like domain), Score=136.1, E-value=2e-37, N=7;
PF00054 (Laminin G domain), Score=75.1, E-value=9.7e-21,
N=1; PF00560 (Leuc>
Length = 1440
Score = 916 bits (2342), Expect = 0.0
Identities = 516/1423 (36%), Positives = 754/1423 (52%), Gaps = 92/1423 (6%)
Query: 34 CPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLHLE 93
CP +C C +V C G L VP+ IP + RLDL N IT+I DF+ L NL+ L L
Sbjct: 17 CPAECVCVDRTVSCVGQQLTEVPQNIPNDTIRLDLQDNEITKIGPNDFSSLMNLKALQLM 76
Query: 94 DNQVSVIERGAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAF 153
DNQ+ I +F L L++LRL++N+++ LP+ +FQ+ KLT LDLSEN I +
Sbjct: 77 DNQIVTIHNQSFSSLVFLQKLRLSRNRIRHLPDNVFQNNLKLTHLDLSENDITVVSDAQL 136
Query: 154 RGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLH 213
+G ++ L LD NHI C+E+ + LE+LTLN N ++ S + R L L
Sbjct: 137 QGPEFLEVLNLDKNHIFCLENNVISSWVSLEVLTLNGNRLTTFEEPS---NARFRQLDLF 193
Query: 214 SNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSE--PP 271
+N CDC L W+ WL + + T+C P++L+G ++ +Q K C
Sbjct: 194 NNPWNCDCRLRWMRKWLEKAEGQNK-TVCATPLNLQGSSIEILQDKFMTCSGNRKRRYKK 252
Query: 272 SCNANSISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYK 331
+C I CP PCTC+ VDCR GL +P NLP EIRLEQN I +IP+ +F K
Sbjct: 253 TCETAEI-CPLPCTCTGTTVDCRDSGLTYVPTNLPPSTTEIRLEQNQISSIPSHSFKNLK 311
Query: 332 KLKRIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKI 391
L R+D+SKN I++I P AF GL +L +LVLYGN IT++ NAN++
Sbjct: 312 NLTRLDLSKNIITEIQPKAFLGLHNLHTLVLYGNNITDLKSDTFEGLGSLQLLLLNANQL 371
Query: 392 NCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADY 451
C+R TF + L++LSLYDN +++IS+ F L S+ TLHLA+NP +CDC+L+WLA
Sbjct: 372 TCIRRGTFDHVPKLSMLSLYDNDIKSISEVTFQNLTSLSTLHLAKNPLICDCNLQWLAQI 431
Query: 452 LQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRC 511
IETSGARC P+RL K+ + + KF+C GSE + S ++ CF+D +CP +C C
Sbjct: 432 NLQKNIETSGARCEQPKRLRKKKFATLPPNKFKCKGSESFVSMYADSCFIDSICPTQCDC 491
Query: 512 EGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKE 571
GT VDC+ + L IP+ +P + T L L+ N +S ++ L NL ++LSNN I
Sbjct: 492 YGTTVDCNKRGLNTIPTSIPRFATQLLLSGNNISTVDLNSNIHVLENLEVLDLSNNHITF 551
Query: 572 VREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSV 631
+ + +F+ + ++EL L N+L V S L+ L L N I C S
Sbjct: 552 INDKSFEKLSKLRELRLNDNKLHHFSSMVLDEQSNLEILDLSGNNIQCFS---------- 601
Query: 632 RLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRRIVSGN-PRC 690
S++ N+ T I I ++ N C+C + L WLR S + P C
Sbjct: 602 ---SIFFNKATRI-----------REIKVIGNDLLCDCRILPLMSWLRSNSSHSIDIPPC 647
Query: 691 QKPFFLKEIPIQDVAIQDFTCDGNEESSC-QLSPRCPEQCTCMETVVRCSNKGLRALPRG 749
Q + D C E +C S CP +C+C++ VVRCSNK L + P
Sbjct: 648 Q------QFQYSDNESDKQRCAAFPEETCSDDSNLCPPKCSCLDRVVRCSNKNLTSFPSR 701
Query: 750 MPKDVTELYLEGNHLTAVP-RELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSY 808
+P D TELYL+ N++ +P +L+ L LT +DLS+N + L N TFSN++ LSTLI+SY
Sbjct: 702 IPFDTTELYLDANYINEIPAHDLNRLYSLTKLDLSHNRLISLENNTFSNLTRLSTLIISY 761
Query: 809 NRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWL 868
N+LRC+ AFNGL +LR+L+LHGNDIS +P+ +F++LTS++H+A+G+N L+CDC++ W
Sbjct: 762 NKLRCLQPLAFNGLNALRILSLHGNDISFLPQSAFSNLTSITHIAVGSNSLYCDCNMAWF 821
Query: 869 SEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNN 928
S+W+K+ + E GIARC P ++++LLLT ++F C V + KC+ CL+SPCKNN
Sbjct: 822 SKWIKSKFIEAGIARCEYPNTVSNQLLLTAQPYQFTCDSKVPTKLATKCDLCLNSPCKNN 881
Query: 929 GTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGF 988
C Y C C + G C I+ C +PC + TC ++ + + F+C C GF
Sbjct: 882 AICETTSSRKYTCNCTPGFYGVHCENQIDACYGSPCLNNATCKVAQAGR--FNCYCNKGF 939
Query: 989 EGQRXXXXXXXXXXXXXXXXATCVD---------------GINNYVCICPPNYTGELCDE 1033
EG CVD IN+Y C CP Y G+ C++
Sbjct: 940 EGDYCEKNIDDCVNSKCENGGKCVDLVRFCSEELKNFQSFQINSYRCDCPMEYEGKHCED 999
Query: 1034 VIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTI 1093
+++C +LN C++ KCIP++ +SC C PG++G CET+ DDC +C++G CVD I
Sbjct: 1000 KLEYCTKKLNPCENNGKCIPINGSYSCMCSPGFTGNNCETNIDDCKNVECQNGGSCVDGI 1059
Query: 1094 NGYTCTCPQGFSGPFCEHPPPMVL--LQTSPCDQYECQNGAQCIVVQQEP--TCRCPPGF 1149
Y C C G++G +CE PP M + +T C Q C G +C+ Q TC+C GF
Sbjct: 1060 LSYDCLCRPGYAGQYCEIPPMMDMEYQKTDACQQSACGQG-ECVASQNSSDFTCKCHEGF 1118
Query: 1150 AGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELY 1209
+GP C++ ++V F +Y LA + I++ + T GILLY GD+ ++ ELY
Sbjct: 1119 SGPSCDRQMSVGFKNPGAY--LALDPLASDGTITMTLRTTSKIGILLYYGDDHFVSAELY 1176
Query: 1210 QGHVRLVYDSLSSPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKG---TPKSLGKLQ 1266
G V+LVY + P + +YS VNDG H DK ++ GK
Sbjct: 1177 DGRVKLVYYIGNFPASHMYSSVKVNDGLPHRISIRTSERKCFLQIDKNPVQIVENSGKSD 1236
Query: 1267 KQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSL 1326
+ G LY+GG+P A R+ + GCI + I NE+ +++
Sbjct: 1237 QLITKG-KEMLYIGGLPIEKSQDAKRRFHVKNSESLKGCISSITI-NEVPINLQQALENV 1294
Query: 1327 GVSPGCKSCTV-------CKHGLC--RSVEKDSVVCECRPGWTGPLCDQEARDPC--LGH 1375
C S TV C +G C ++ +C+C ++G CD E R C
Sbjct: 1295 NTEQSC-SATVNFCAGIDCGNGKCTNNALSPKGYMCQCDSHFSGEHCD-EKRIKCDKQKF 1352
Query: 1376 RCHH--GKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFK 1416
R HH +C + + +C GG+ N C+A K
Sbjct: 1353 RRHHIENECRSVDRIKIAECNGYCGGE--------QNCCTAVK 1387
Score = 326 bits (828), Expect = 8e-88
Identities = 191/630 (30%), Positives = 307/630 (48%), Gaps = 39/630 (6%)
Query: 277 SISCPSPCTCSNNIVDCRGKGLMEIPANLPEGIVEIRLEQNSIKAIPAGAFTQYKKLK-- 334
S +CP+ C C + V C G+ L E+P N+P + + L+ N I I F+ LK
Sbjct: 14 SATCPAECVCVDRTVSCVGQQLTEVPQNIPNDTIRLDLQDNEITKIGPNDFSSLMNLKAL 73
Query: 335 ----------------------RIDISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAK 372
++ +S+N+I + + FQ LT L L N IT ++
Sbjct: 74 QLMDNQIVTIHNQSFSSLVFLQKLRLSRNRIRHLPDNVFQNNLKLTHLDLSENDITVVSD 133
Query: 373 GXXXXXXXXXXXXXNANKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTL 432
+ N I CL N +L +L+L N+L T + A + L
Sbjct: 134 AQLQGPEFLEVLNLDKNHIFCLENNVISSWVSLEVLTLNGNRLTTFEEPSNA---RFRQL 190
Query: 433 HLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYR 492
L NP+ CDC L+W+ +L+ + C++P L I ++ K CSG+ +
Sbjct: 191 DLFNNPWNCDCRLRWMRKWLEKAEGQNKTV-CATPLNLQGSSIEILQDKFMTCSGNR--K 247
Query: 493 SRFSSECFMDLVCPEKCRCEGTIVDCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGI 552
R+ C +CP C C GT VDC + L +P++LP T++RL N++S + +
Sbjct: 248 RRYKKTCETAEICPLPCTCTGTTVDCRDSGLTYVPTNLPPSTTEIRLEQNQISSIPSHS- 306
Query: 553 FKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLML 612
FK L NL +++LS N I E++ AF G ++ L+L GN + + F GL L+ L+L
Sbjct: 307 FKNLKNLTRLDLSKNIITEIQPKAFLGLHNLHTLVLYGNNITDLKSDTFEGLGSLQLLLL 366
Query: 613 RSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLA 672
+N + C+ TF + + +LSLYDN I +I+ F L SLST++L NP C+C+L
Sbjct: 367 NANQLTCIRRGTFDHVPKLSMLSLYDNDIKSISEVTFQNLTSLSTLHLAKNPLICDCNLQ 426
Query: 673 WLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEE------SSCQLSPRCP 726
WL + ++ I + RC++P L++ + F C G+E SC + CP
Sbjct: 427 WLAQINLQKNIETSGARCEQPKRLRKKKFATLPPNKFKCKGSESFVSMYADSCFIDSICP 486
Query: 727 EQCTCMETVVRCSNKGLRALPRGMPKDVTELYLEGNHLTAVP--RELSALRHLTLIDLSN 784
QC C T V C+ +GL +P +P+ T+L L GN+++ V + L +L ++DLSN
Sbjct: 487 TQCDCYGTTVDCNKRGLNTIPTSIPRFATQLLLSGNNISTVDLNSNIHVLENLEVLDLSN 546
Query: 785 NSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFN 844
N I+ + + +F +S L L L+ N+L + +L +L L GN+I FN
Sbjct: 547 NHITFINDKSFEKLSKLRELRLNDNKLHHFSSMVLDEQSNLEILDLSGNNIQCFSSIFFN 606
Query: 845 DLTSLSHLALGTNPLHCDCSLRWLSEWVKA 874
T + + + N L CDC + L W+++
Sbjct: 607 KATRIREIKVIGNDLLCDCRILPLMSWLRS 636
Score = 65.2 bits (156), Expect = 5e-09
Identities = 36/105 (34%), Positives = 45/105 (42%), Gaps = 9/105 (8%)
Query: 1350 SVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLC------ 1402
S C C PG+TG C+ D C C +G CV SY C C GY G C
Sbjct: 1023 SYSCMCSPGFTGNNCETNI-DDCKNVECQNGGSCVDGILSYDCLCRPGYAGQYCEIPPMM 1081
Query: 1403 DNKNDSANACSAFKCHHGQCHISDQGEPY-CLCQPGFSGEHCQQE 1446
D + +AC C G+C S + C C GFSG C ++
Sbjct: 1082 DMEYQKTDACQQSACGQGECVASQNSSDFTCKCHEGFSGPSCDRQ 1126
Score = 58.9 bits (140), Expect = 4e-07
Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 13/107 (12%)
Query: 1344 RSVEKDSVVCECRPGWTGPLCDQEAR------DPCLGHRCHHGKCVATGTSYMCKCAEGY 1397
+S + +S C+C + G C+ + +PC ++GKC+ SY C C+ G+
Sbjct: 977 QSFQINSYRCDCPMEYEGKHCEDKLEYCTKKLNPCE----NNGKCIPINGSYSCMCSPGF 1032
Query: 1398 GGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
G+ C+ D C +C +G + CLC+PG++G++C+
Sbjct: 1033 TGNNCETNIDD---CKNVECQNGGSCVDGILSYDCLCRPGYAGQYCE 1076
Score = 49.6 bits (116), Expect = 3e-04
Identities = 25/79 (31%), Positives = 38/79 (47%), Gaps = 6/79 (7%)
Query: 1370 DPCLGHRCHHGKCVATGTS--YMCKCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISD 1426
D CL C + T +S Y C C G+ G C+N+ D AC C ++ C ++
Sbjct: 871 DLCLNSPCKNNAICETTSSRKYTCNCTPGFYGVHCENQID---ACYGSPCLNNATCKVAQ 927
Query: 1427 QGEPYCLCQPGFSGEHCQQ 1445
G C C GF G++C++
Sbjct: 928 AGRFNCYCNKGFEGDYCEK 946
Score = 45.7 bits (106), Expect = 0.004
Identities = 29/108 (26%), Positives = 49/108 (44%), Gaps = 9/108 (8%)
Query: 1408 SANACSAFKCHHGQCH---ISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGY 1464
+ N C+ C +G+C +S +G C C FSGEHC ++ + ++ RR
Sbjct: 1303 TVNFCAGIDCGNGKCTNNALSPKGY-MCQCDSHFSGEHCDEKRI---KCDKQKFRRHHIE 1358
Query: 1465 ASCATASKVPIMECRXXXXXXXXXXT--RSKRRKYVFQCTDGSSFVEE 1510
C + ++ I EC T + K+RK C +G+++V E
Sbjct: 1359 NECRSVDRIKIAECNGYCGGEQNCCTAVKKKQRKVKMICKNGTTYVRE 1406
Score = 35.2 bits (79), Expect = 5.7
Identities = 31/135 (22%), Positives = 54/135 (39%), Gaps = 19/135 (14%)
Query: 1345 SVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDN 1404
+V +S+ C+C W + + + RC + V+ + + A+ Y CD+
Sbjct: 806 AVGSNSLYCDCNMAWFSKWIKSKFIEAGIA-RCEYPNTVS---NQLLLTAQPYQFT-CDS 860
Query: 1405 KNDSANACSAFKC------HHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPCLGQ 1452
K + A C ++ C + + C C PGF G HC+ + +PCL
Sbjct: 861 KVPTKLATKCDLCLNSPCKNNAICETTSSRKYTCNCTPGFYGVHCENQIDACYGSPCLNN 920
Query: 1453 VVREVIRRQKGYASC 1467
+V Q G +C
Sbjct: 921 ATCKV--AQAGRFNC 933
>dbj|BAA32465.2| (AB011537) MEGF4 [Homo sapiens]
Length = 664
Score = 737 bits (1883), Expect = 0.0
Identities = 330/659 (50%), Positives = 427/659 (64%), Gaps = 5/659 (0%)
Query: 790 LTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTLHGNDISSVPEGSFNDLTSL 849
L+N +F+NMS L+TLILSYN L+CIP AF GLRSLR+L+LHGNDIS++ EG F D+TSL
Sbjct: 2 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 61
Query: 850 SHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPV 909
SHLA+G NPL+CDC LRWLS WVK GYKEPGIARC+ P+ M +LLLTTP +F+C+GP
Sbjct: 62 SHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPP 121
Query: 910 DINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGT 969
+ + AKC+ CLSSPC+N GTC DP+E+YRCACP YKG+DC V +++C PC++GGT
Sbjct: 122 TLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGT 181
Query: 970 CHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGE 1029
CH + F+CSCP GFEG CVDG+ NY C CP Y G+
Sbjct: 182 CHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGK 241
Query: 1030 LCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQC 1089
C++++D C P+LN CQHEA+C+ G CEC+PGY+G C + DDC H+C++GAQC
Sbjct: 242 ACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQC 301
Query: 1090 VDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGF 1149
+D +N Y+C C +G+SG CE PP + SPC+ ECQNGA C+ P C+C PGF
Sbjct: 302 MDEVNSYSCLCAEGYSGQLCEIPPHLP-APKSPCEGTECQNGANCVDQGNRPVCQCLPGF 360
Query: 1150 AGPRCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELY 1209
GP CEKL++VNFV +D+Y++ + P+ANI+LQV+T +DNGILLY GDND +A+ELY
Sbjct: 361 GGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILLYNGDNDHIAVELY 420
Query: 1210 QGHVRLVYDSLSSPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQP 1269
QGHVR+ YD S P + +YS ET+NDGQFH+ D G+P ++ K
Sbjct: 421 QGHVRVSYDPGSYPSSAIYSAETINDGQFHTVELVAFDQMVNLSIDGGSPMTMDNFGKHY 480
Query: 1270 AVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVS 1329
+ +PLY+GG+P +A R GFHGCI + INNELQDF + GV
Sbjct: 481 TLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHGCIRNLYINNELQDFTKTQMKP-GVV 539
Query: 1330 PGCKSC--TVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCV-ATG 1386
PGC+ C C HG+C+ +C C GW G CDQ A PC GH+C HG+CV
Sbjct: 540 PGCEPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDA 599
Query: 1387 TSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQ 1445
SY C+C +GY G LC+ A C +C HG C S +C+C PGFSGE C+Q
Sbjct: 600 LSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQ 658
Score = 88.5 bits (216), Expect = 5e-16
Identities = 45/135 (33%), Positives = 71/135 (52%), Gaps = 7/135 (5%)
Query: 389 NKINCLRVNTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWL 448
N + C+ FQ L++L LLSL+ N + T+ +G+FA + S+ L + NP CDCHL+WL
Sbjct: 21 NALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPLYCDCHLRWL 80
Query: 449 ADYLQDNPIETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEK 508
+ +++ E ARC+ P+ + K + +KKF C G + + DL
Sbjct: 81 SSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGP----PTLAVQAKCDLCLSSP 136
Query: 509 CRCEGTIVDCSNQKL 523
C+ +GT C N L
Sbjct: 137 CQNQGT---CHNDPL 148
Score = 84.3 bits (205), Expect = 1e-14
Identities = 51/148 (34%), Positives = 72/148 (48%), Gaps = 9/148 (6%)
Query: 601 FRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINL 660
F +S L TL+L N + C+ F GL S+RLLSL+ N I+T+ G F + SLS + +
Sbjct: 7 FTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAI 66
Query: 661 LSNPFNCNCHLAWLGKWLRKRRIVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEESSCQ 720
+NP C+CHL WL W++ G RC P ++ + + F C G + Q
Sbjct: 67 GANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLAVQ 126
Query: 721 ------LSPRCPEQCTCME---TVVRCS 739
LS C Q TC V RC+
Sbjct: 127 AKCDLCLSSPCQNQGTCHNDPLEVYRCA 154
Score = 75.7 bits (183), Expect = 4e-12
Identities = 41/145 (28%), Positives = 67/145 (45%), Gaps = 3/145 (2%)
Query: 148 IPRKAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKI 207
+ +F ++ + L L N + CI AF+ LR L +L+L+ N+IS + F + +
Sbjct: 2 LSNSSFTNMSQLTTLILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSL 61
Query: 208 RTLRLHSNHLYCDCHLAWLSDWLRQRRTVGQFTLCMAPVHLRGFNVADVQKKEYVCPAPH 267
L + +N LYCDCHL WLS W++ C P + G + K++ C P
Sbjct: 62 SHLAIGANPLYCDCHLRWLSSWVKTGYKEPGIARCAGPQDMEGKLLLTTPAKKFECQGPP 121
Query: 268 SEPPSCNAN---SISCPSPCTCSNN 289
+ + S C + TC N+
Sbjct: 122 TLAVQAKCDLCLSSPCQNQGTCHND 146
Score = 39.9 bits (91), Expect = 0.22
Identities = 20/56 (35%), Positives = 30/56 (52%)
Query: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAFQDLKQLERLRLNKNKL 121
L L N + I + F GL++LR+L L N +S ++ G F D+ L L + N L
Sbjct: 16 LILSYNALQCIPPLAFQGLRSLRLLSLHGNDISTLQEGIFADVTSLSHLAIGANPL 71
Score = 35.6 bits (80), Expect = 4.3
Identities = 24/88 (27%), Positives = 37/88 (41%), Gaps = 11/88 (12%)
Query: 1293 QGTDRPLGGFHGCIHEVRINNELQDFK---------ALPPQSLGVSPGCKSCTVCKHGLC 1343
Q D P G H C+H + + + AL Q+ ++ C+ C HG C
Sbjct: 578 QPADGPCHG-HKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQ-CLHGHC 635
Query: 1344 RSVEKDSVVCECRPGWTGPLCDQEARDP 1371
++ C C PG++G LC+Q P
Sbjct: 636 QASGTKGAHCVCDPGFSGELCEQGQGPP 663
>pir||T34555 hypothetical protein DKFZp434N0435.1 - human
emb|CAB59249.1| (AL122074) hypothetical protein [Homo sapiens]
Length = 333
Score = 615 bits (1569), Expect = e-174
Identities = 308/322 (95%), Positives = 309/322 (95%)
Query: 337 DISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKINCLRV 396
DISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKG NANKINCLRV
Sbjct: 12 DISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRV 71
Query: 397 NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNP 456
NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNP
Sbjct: 72 NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNP 131
Query: 457 IETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIV 516
IETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIV
Sbjct: 132 IETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIV 191
Query: 517 DCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGA 576
DCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGA
Sbjct: 192 DCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGA 251
Query: 577 FDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSL 636
FDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSL
Sbjct: 252 FDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSL 311
Query: 637 YDNRITTITPGAFTTLVSLSTI 658
YDNRITTITPGAFTTLVSLST+
Sbjct: 312 YDNRITTITPGAFTTLVSLSTM 333
Score = 191 bits (480), Expect = 5e-47
Identities = 112/320 (35%), Positives = 169/320 (52%), Gaps = 32/320 (10%)
Query: 563 NLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSN 622
++S N+I ++ AF G S+ L+L GN++ + +F GL L+ L+L +N I C+
Sbjct: 12 DISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRV 71
Query: 623 DTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTINLLSNPFNCNCHLAWLGKWLRKRR 682
+TF L ++ LLSLYDN++ TI+ G F L S+ T++L NPF C+CHL WL +L+
Sbjct: 72 NTFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNP 131
Query: 683 IVSGNPRCQKPFFLKEIPIQDVAIQDFTCDGNEE------SSCQLSPRCPEQCTCMETVV 736
I + RC P L I + + F C G+E+ S C + CPE+C C T+V
Sbjct: 132 IETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIV 191
Query: 737 RCSNKGLRALPRGMPKDVTELYLEGNHLTAVPRE--LSALRHLTLIDLSNNSIS------ 788
CSN+ L +P +P+ VT+L L N ++ + L +L I+LSNN I
Sbjct: 192 DCSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGA 251
Query: 789 ----------MLT--------NYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRVLTL 830
MLT F +S L TL+L N + C+ F GL S+R+L+L
Sbjct: 252 FDGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSL 311
Query: 831 HGNDISSVPEGSFNDLTSLS 850
+ N I+++ G+F L SLS
Sbjct: 312 YDNRITTITPGAFTTLVSLS 331
Score = 182 bits (457), Expect = 3e-44
Identities = 98/321 (30%), Positives = 165/321 (50%), Gaps = 4/321 (1%)
Query: 116 LNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCIEDG 175
++KN++ + FQ LT L L N+I I + F G+ ++ L L+ N I+C+
Sbjct: 13 ISKNQISDIAPDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVN 72
Query: 176 AFRALRDLEILTLNNNNISRILVTSFNHMPKIRTLRLHSNHLYCDCHLAWLSDWLRQRRT 235
F+ L++L +L+L +N + I F + I+TL L N CDCHL WL+D+L+
Sbjct: 73 TFQDLQNLNLLSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPI 132
Query: 236 VGQFTLCMAPVHLRGFNVADVQKKEYVCPAPHSEPPSCNAN---SISCPSPCTCSNNIVD 292
C +P L ++ ++ K++ C ++ + CP C C IVD
Sbjct: 133 ETSGARCSSPRRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGTIVD 192
Query: 293 CRGKGLMEIPANLPEGIVEIRLEQNSIKAIPA-GAFTQYKKLKRIDISKNQISDIAPDAF 351
C + L+ IP++LPE + ++RL N + + A G F + L++I++S N+I ++ AF
Sbjct: 193 CSNQKLVRIPSHLPEYVTDLRLNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAF 252
Query: 352 QGLKSLTSLVLYGNKITEIAKGXXXXXXXXXXXXXNANKINCLRVNTFQDLQNLNLLSLY 411
G S+ L+L GN++ + +N I C+ +TF L ++ LLSLY
Sbjct: 253 DGAASVQELMLTGNQLETVHGRVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLY 312
Query: 412 DNKLQTISKGLFAPLQSIQTL 432
DN++ TI+ G F L S+ T+
Sbjct: 313 DNRITTITPGAFTTLVSLSTM 333
Score = 97.1 bits (238), Expect = 1e-18
Identities = 52/167 (31%), Positives = 89/167 (53%), Gaps = 4/167 (2%)
Query: 768 PRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNRLRCIPVHAFNGLRSLRV 827
P L+ LT + L N I+ + F + L L+L+ N++ C+ V+ F L++L +
Sbjct: 23 PDAFQGLKSLTSLVLYGNKITEIAKGLFDGLVSLQLLLLNANKINCLRVNTFQDLQNLNL 82
Query: 828 LTLHGNDISSVPEGSFNDLTSLSHLALGTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSP 887
L+L+ N + ++ +G F L S+ L L NP CDC L+WL+++++ E ARCSSP
Sbjct: 83 LSLYDNKLQTISKGLFAPLQSIQTLHLAQNPFVCDCHLKWLADYLQDNPIETSGARCSSP 142
Query: 888 EPMADRLLLTTPTHRFQCKGPVDI--NIVAKCNACLSSP--CKNNGT 930
+A++ + + +F+C G D ++C L P C+ GT
Sbjct: 143 RRLANKRISQIKSKKFRCSGSEDYRSRFSSECFMDLVCPEKCRCEGT 189
Score = 85.4 bits (208), Expect = 4e-15
Identities = 50/180 (27%), Positives = 85/180 (46%), Gaps = 25/180 (13%)
Query: 32 VACPTKCTCSAASVDCHGLGLRAVPRGIPRNAERLDLDRNNITRITKMDFAGLKNLRVLH 91
+ CP KC C VDC L +P +P + + L
Sbjct: 178 LVCPEKCRCEGTIVDCSNQKLVRIPSHLP------------------------EYVTDLR 213
Query: 92 LEDNQVSVIER-GAFQDLKQLERLRLNKNKLQVLPELLFQSTPKLTRLDLSENQIQGIPR 150
L DN+VSV+E G F+ L L ++ L+ NK++ + E F + L L+ NQ++ +
Sbjct: 214 LNDNEVSVLEATGIFKKLPNLRKINLSNNKIKEVREGAFDGAASVQELMLTGNQLETVHG 273
Query: 151 KAFRGITDVKNLQLDNNHISCIEDGAFRALRDLEILTLNNNNISRILVTSFNHMPKIRTL 210
+ FRG++ +K L L +N I C+ + F L + +L+L +N I+ I +F + + T+
Sbjct: 274 RVFRGLSGLKTLMLRSNLIGCVSNDTFAGLSSVRLLSLYDNRITTITPGAFTTLVSLSTM 333
>pir||A31640 epidermal growth factor-like protein slit - fruit fly (Drosophila
melanogaster) (fragment)
gb|AAA72722.1| (M23543) [Drosophila melanogaster slit locus encoding a protein
associated with neural development with 52D EGF
homologous domains gene, exons 1 and 2 (partial).], gene
product
Length = 530
Score = 355 bits (902), Expect = 2e-96
Identities = 188/528 (35%), Positives = 273/528 (51%), Gaps = 21/528 (3%)
Query: 890 MADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKG 949
M D+L+L+TP+ F C+G V +I+AKCNAC PC+N C P Y+C C Y G
Sbjct: 1 MKDKLILSTPSSSFVCRGRVRNDILAKCNACFEQPCQNQAQCVALPQREYQCLCQPGYHG 60
Query: 950 KDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXX-XXX 1008
K C I+ C NPC++ TC + + + FSC C G+ G R
Sbjct: 61 KHCEFMIDACYGNPCRNNATCTVLEEGR--FSCQCAPGYTGARCETNIDDCLGEIKCQNN 118
Query: 1009 ATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSG 1068
ATC+DG+ +Y C C P ++GE CD I C PE N C + AKC+ +SC+C G+ G
Sbjct: 119 ATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPCANGAKCMDHFTHYSCDCQAGFHG 178
Query: 1069 KLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCE--HPPPMVLLQTSPCDQY 1126
C + DDC H C++G CVD IN Y C CP ++G +CE + M+ QTSPC +
Sbjct: 179 TNCTDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMMYPQTSPCQNH 238
Query: 1127 ECQNGA--QCIVVQQEPTCRCPPGFAGPRCEKLITVNFVGKDSYVELASAKVRPQANISL 1184
EC++G Q + CRC PG+ G CE L +++FV +S+VEL + RP+AN+++
Sbjct: 239 ECKHGVCFQPNAQGSDYLCRCHPGYTGKWCEYLTSISFVHNNSFVELEPLRTRPEANVTI 298
Query: 1185 QVATDKDNGILLYKGDNDPLALELYQGHVRLVYDSLSSPPTTVYSVETVNDGQFHSXXXX 1244
V + NGIL+Y G + LA+EL+ G +R+ YD + P +T+YS E V DG++H+
Sbjct: 299 -VFSSGQNGILMYDGQDAHLAVELFNGRIRVSYDVGNHPVSTMYSFEMVADGKYHAVELL 357
Query: 1245 XXXXXXXXXXDKGTPKSLGKLQKQPAVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHG 1304
D+G +S+ + + +P++LGG+P A + R L F G
Sbjct: 358 AIKKNFTLRVDRGLARSIINEGSNDYLKLTTPMFLGGLPVDPAQQAYKNWQIRNLTSFKG 417
Query: 1305 CIHEVRINNELQDFKALPPQSLGVSPGCKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLC 1364
C+ EV IN++L DF Q ++PGC L +++ E P
Sbjct: 418 CMKEVWINHKLVDFGNAQRQQ-KITPGC--------ALLEGEQQEEEDDEQDFMDETPHI 468
Query: 1365 DQEARDPCLGHRCHHG-KCVATGTS---YMCKCAEGYGGDLCDNKNDS 1408
+E DPCL ++C G +CV + Y CKC G G CD S
Sbjct: 469 KEEPVDPCLENKCRRGSRCVPNSNARDGYQCKCKHGQRGRYCDQGEGS 516
Score = 65.6 bits (157), Expect = 4e-09
Identities = 33/101 (32%), Positives = 47/101 (45%), Gaps = 10/101 (9%)
Query: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLCDNKN----- 1406
C+C+ G+ G C D C H C +G CV Y C+C + Y G C+ N
Sbjct: 170 CDCQAGFHGTNCTDNI-DDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEGHNMISMM 228
Query: 1407 -DSANACSAFKCHHGQCHISD-QGEPY-CLCQPGFSGEHCQ 1444
+ C +C HG C + QG Y C C PG++G+ C+
Sbjct: 229 YPQTSPCQNHECKHGVCFQPNAQGSDYLCRCHPGYTGKWCE 269
Score = 60.5 bits (144), Expect = 1e-07
Identities = 32/122 (26%), Positives = 55/122 (44%), Gaps = 19/122 (15%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEAR------DPCLGHRCHHGKCVAT 1385
C++ C G+ +S CEC+PG++G CD + + +PC + KC+
Sbjct: 115 CQNNATCIDGV------ESYKCECQPGFSGEFCDTKIQFCSPEFNPC----ANGAKCMDH 164
Query: 1386 GTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQ 1445
T Y C C G+ G C D+ + C C +G + + C C ++G++C+
Sbjct: 165 FTHYSCDCQAGFHGTNC---TDNIDDCQNHMCQNGGTCVDGINDYQCRCPDDYTGKYCEG 221
Query: 1446 EN 1447
N
Sbjct: 222 HN 223
Score = 60.1 bits (143), Expect = 2e-07
Identities = 36/117 (30%), Positives = 50/117 (41%), Gaps = 13/117 (11%)
Query: 1343 CRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKC--VATGTSYMCKCAEGYGGD 1400
C ++ + C C+PG+ G C+ D C G+ C + V + C+CA GY G
Sbjct: 42 CVALPQREYQCLCQPGYHGKHCEFMI-DACYGNPCRNNATCTVLEEGRFSCQCAPGYTGA 100
Query: 1401 LCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE--------NPC 1449
C+ D + KC + I C CQPGFSGE C + NPC
Sbjct: 101 RCETNID--DCLGEIKCQNNATCIDGVESYKCECQPGFSGEFCDTKIQFCSPEFNPC 155
Score = 43.0 bits (99), Expect = 0.026
Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 1410 NACSAFKCHH-GQCHISDQGEPYCLCQPGFSGEHCQ------QENPCLGQVVREVIRRQK 1462
NAC C + QC Q E CLCQPG+ G+HC+ NPC V+ +
Sbjct: 29 NACFEQPCQNQAQCVALPQREYQCLCQPGYHGKHCEFMIDACYGNPCRNNATCTVLEEGR 88
Query: 1463 GYASCA 1468
CA
Sbjct: 89 FSCQCA 94
>pir||T22025 hypothetical protein F40E10.4 - Caenorhabditis elegans (fragment)
Length = 601
Score = 291 bits (737), Expect = 4e-77
Identities = 188/610 (30%), Positives = 280/610 (45%), Gaps = 62/610 (10%)
Query: 872 VKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC 931
+K+ + E GIARC P ++++LLLT ++F C V + KC+ CL+SPCKNN C
Sbjct: 1 IKSKFIEAGIARCEYPNTVSNQLLLTAQPYQFTCDSKVPTKLATKCDLCLNSPCKNNAIC 60
Query: 932 TQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQ 991
Y C C + G C I+ C +PC + TC ++ + + F+C C GFEG
Sbjct: 61 ETTSSRKYTCNCTPGFYGVHCENQIDACYGSPCLNNATCKVAQAGR--FNCYCNKGFEGD 118
Query: 992 RXXXXXXXXXXXXXXXXATCVD---------------GINNYVCICPPNYTGELCDEVID 1036
CVD IN+Y C CP Y G+ C++ ++
Sbjct: 119 YCEKNIDDCVNSKCENGGKCVDLVRFCSEELKNFQSFQINSYRCDCPMEYEGKHCEDKLE 178
Query: 1037 HCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGY 1096
+C +LN C++ KCIP++ +SC C PG++G CET+ DDC +C++G CVD I Y
Sbjct: 179 YCTKKLNPCENNGKCIPINGSYSCMCSPGFTGNNCETNIDDCKNVECQNGGSCVDGILSY 238
Query: 1097 TCTCPQGFSGPFCEHPPPMVL--LQTSPCDQYECQNGAQCIVVQQEP--TCRCPPGFAGP 1152
C C G++G +CE PP M + +T C Q C G +C+ Q TC+C GF+GP
Sbjct: 239 DCLCRPGYAGQYCEIPPMMDMEYQKTDACQQSACGQG-ECVASQNSSDFTCKCHEGFSGP 297
Query: 1153 RCEKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLYKGDNDPLALELYQGH 1212
C++ ++V F +Y LA + I++ + T GILLY GD+ ++ ELY G
Sbjct: 298 SCDRQMSVGFKNPGAY--LALDPLASDGTITMTLRTTSKIGILLYYGDDHFVSAELYDGR 355
Query: 1213 VRLVYDSLSSPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKG---TPKSLGKLQKQP 1269
V+LVY + P + +YS VNDG H DK ++ GK +
Sbjct: 356 VKLVYYIGNFPASHMYSSVKVNDGLPHRISIRTSERKCFLQIDKNPVQIVENSGKSDQLI 415
Query: 1270 AVGINSPLYLGGIPTSTGLSALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVS 1329
G LY+GG+P A R+ + GCI + I NE+ +++
Sbjct: 416 TKG-KEMLYIGGLPIEKSQDAKRRFHVKNSESLKGCISSITI-NEVPINLQQALENVNTE 473
Query: 1330 PGCKSCTV-------CKHGLC--RSVEKDSVVCECRPGWTGPLCDQEARDPC--LGHRCH 1378
C S TV C +G C ++ +C+C ++G CD E R C R H
Sbjct: 474 QSC-SATVNFCAGIDCGNGKCTNNALSPKGYMCQCDSHFSGEHCD-EKRIKCDKQKFRRH 531
Query: 1379 H--GKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFK---------CHHGQCHISD- 1426
H +C + + +C GG+ N C+A K C +G IS
Sbjct: 532 HIENECRSVDRIKIAECNGYCGGE--------QNCCTAVKKKQRKVKMICKNGTTKISTV 583
Query: 1427 QGEPYCLCQP 1436
C C+P
Sbjct: 584 HIIRQCQCEP 593
Score = 65.2 bits (156), Expect = 5e-09
Identities = 36/105 (34%), Positives = 45/105 (42%), Gaps = 9/105 (8%)
Query: 1350 SVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLC------ 1402
S C C PG+TG C+ D C C +G CV SY C C GY G C
Sbjct: 199 SYSCMCSPGFTGNNCETNI-DDCKNVECQNGGSCVDGILSYDCLCRPGYAGQYCEIPPMM 257
Query: 1403 DNKNDSANACSAFKCHHGQCHISDQGEPY-CLCQPGFSGEHCQQE 1446
D + +AC C G+C S + C C GFSG C ++
Sbjct: 258 DMEYQKTDACQQSACGQGECVASQNSSDFTCKCHEGFSGPSCDRQ 302
Score = 58.9 bits (140), Expect = 4e-07
Identities = 29/107 (27%), Positives = 53/107 (49%), Gaps = 13/107 (12%)
Query: 1344 RSVEKDSVVCECRPGWTGPLCDQEAR------DPCLGHRCHHGKCVATGTSYMCKCAEGY 1397
+S + +S C+C + G C+ + +PC ++GKC+ SY C C+ G+
Sbjct: 153 QSFQINSYRCDCPMEYEGKHCEDKLEYCTKKLNPCE----NNGKCIPINGSYSCMCSPGF 208
Query: 1398 GGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
G+ C+ D C +C +G + CLC+PG++G++C+
Sbjct: 209 TGNNCETNIDD---CKNVECQNGGSCVDGILSYDCLCRPGYAGQYCE 252
Score = 55.0 bits (130), Expect = 6e-06
Identities = 35/133 (26%), Positives = 54/133 (40%), Gaps = 26/133 (19%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATG---- 1386
C + C+ + C C G+ G C++ D C+ +C +G KCV
Sbjct: 88 CYGSPCLNNATCKVAQAGRFNCYCNKGFEGDYCEKNI-DDCVNSKCENGGKCVDLVRFCS 146
Query: 1387 -----------TSYMCKCAEGYGGDLCDNKND----SANACSAFKCHHGQCHISDQGEPY 1431
SY C C Y G C++K + N C ++G+C I G
Sbjct: 147 EELKNFQSFQINSYRCDCPMEYEGKHCEDKLEYCTKKLNPCE----NNGKC-IPINGSYS 201
Query: 1432 CLCQPGFSGEHCQ 1444
C+C PGF+G +C+
Sbjct: 202 CMCSPGFTGNNCE 214
Score = 49.6 bits (116), Expect = 3e-04
Identities = 25/79 (31%), Positives = 38/79 (47%), Gaps = 6/79 (7%)
Query: 1370 DPCLGHRCHHGKCVATGTS--YMCKCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISD 1426
D CL C + T +S Y C C G+ G C+N+ D AC C ++ C ++
Sbjct: 47 DLCLNSPCKNNAICETTSSRKYTCNCTPGFYGVHCENQID---ACYGSPCLNNATCKVAQ 103
Query: 1427 QGEPYCLCQPGFSGEHCQQ 1445
G C C GF G++C++
Sbjct: 104 AGRFNCYCNKGFEGDYCEK 122
Score = 46.1 bits (107), Expect = 0.003
Identities = 30/117 (25%), Positives = 51/117 (42%), Gaps = 9/117 (7%)
Query: 1408 SANACSAFKCHHGQCH---ISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGY 1464
+ N C+ C +G+C +S +G C C FSGEHC ++ + ++ RR
Sbjct: 479 TVNFCAGIDCGNGKCTNNALSPKGY-MCQCDSHFSGEHCDEKRI---KCDKQKFRRHHIE 534
Query: 1465 ASCATASKVPIMECRXXXXXXXXXXT--RSKRRKYVFQCTDGSSFVEEVERHLECGC 1519
C + ++ I EC T + K+RK C +G++ + V +C C
Sbjct: 535 NECRSVDRIKIAECNGYCGGEQNCCTAVKKKQRKVKMICKNGTTKISTVHIIRQCQC 591
>gb|AAD19349.1| (AF088902) SLIT1 protein [Mus musculus]
Length = 111
Score = 203 bits (512), Expect = 1e-50
Identities = 90/111 (81%), Positives = 96/111 (86%)
Query: 1413 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQENPCLGQVVREVIRRQKGYASCATASK 1472
+AFKCHHGQCHISD+GEPYCLCQPGFSG HC+QENPC+G++VRE IRRQK YASCATASK
Sbjct: 1 AAFKCHHGQCHISDRGEPYCLCQPGFSGHHCEQENPCMGEIVREAIRRQKDYASCATASK 60
Query: 1473 VPIMECRXXXXXXXXXXTRSKRRKYVFQCTDGSSFVEEVERHLECGCLACS 1523
VPIMECR RSKRRKYVFQCTDGSSFVEEVERHLECGC ACS
Sbjct: 61 VPIMECRGGCGSQCCQPIRSKRRKYVFQCTDGSSFVEEVERHLECGCRACS 111
Score = 43.4 bits (100), Expect = 0.020
Identities = 24/97 (24%), Positives = 39/97 (39%), Gaps = 11/97 (11%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLG--------HRCHHGKCVATGTSY 1389
C HG C ++ C C+PG++G C+QE +PC+G + + C
Sbjct: 5 CHHGQCHISDRGEPYCLCQPGFSGHHCEQE--NPCMGEIVREAIRRQKDYASCATASKVP 62
Query: 1390 MCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISD 1426
+ +C G G C S F+C G + +
Sbjct: 63 IMECRGGCGSQCCQPIR-SKRRKYVFQCTDGSSFVEE 98
>sp|Q07008|NTC1_RAT NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 PRECURSOR
emb|CAA40667.1| (X57405) rat notch protein [Rattus rattus]
Length = 2531
Score = 199 bits (501), Expect = 2e-49
Identities = 103/301 (34%), Positives = 137/301 (45%), Gaps = 14/301 (4%)
Query: 855 GTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIV 914
G N CDC+ W E C + D T R GP N
Sbjct: 733 GLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP---NCQ 789
Query: 915 AKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSD 974
N C S+PC N GTC D V Y+C CP Y G C V + C +PC++ G C S+
Sbjct: 790 TNINECASNPCLNQGTCIDD-VAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESE 848
Query: 975 SHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEV 1034
+ + FSC CP G++GQ A+C + +Y C+C YTG C+
Sbjct: 849 DY-ESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESD 907
Query: 1035 IDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTIN 1094
ID C P N C + C C+C+PG+ G CE D ++C + C++GA C D ++
Sbjct: 908 IDDCRP--NPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECATNPCQNGANCTDCVD 965
Query: 1095 GYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
YTCTCP GF+G CE+ T C + C NG C+ TC CPPGF G C
Sbjct: 966 SYTCTCPTGFNGIHCEN-------NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
Query: 1155 E 1155
+
Sbjct: 1019 Q 1019
Score = 180 bits (451), Expect = 1e-43
Identities = 78/240 (32%), Positives = 119/240 (49%), Gaps = 13/240 (5%)
Query: 920 CLSSPCKNNGTCTQ-DPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKD 978
C +SPCKN+G C + + E + C CP ++G+ C + IN C+++PC+HG +C ++
Sbjct: 833 CATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNG--- 889
Query: 979 GFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHC 1038
+ C C G+ G+ +C DG+N C C P + G C+E I+ C
Sbjct: 890 SYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINEC 949
Query: 1039 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTC 1098
N CQ+ A C ++C C G++G CE + DC C +G CVD IN +TC
Sbjct: 950 AT--NPCQNGANCTDCVDSYTCTCPTGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTC 1007
Query: 1099 TCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
CP GF+G +C++ + CD C +G C C CP G+ G C+ L+
Sbjct: 1008 LCPPGFTGSYCQY-------DVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLV 1060
Score = 168 bits (421), Expect = 4e-40
Identities = 86/253 (33%), Positives = 118/253 (45%), Gaps = 25/253 (9%)
Query: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
N C S PC + GTC QD Y+C CP Y G +C + C PC++GG C +++
Sbjct: 1023 NECDSRPCLHGGTC-QDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGKCWQTNTQ- 1080
Query: 978 DGFSCSCPLGFEG----------QRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYT 1027
+ C C G+ G + CVD + + C C YT
Sbjct: 1081 --YHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYT 1138
Query: 1028 GELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGA 1087
G C++ +D C P N CQ+ A C GFSC+CV GY G C + ++C++ C++G
Sbjct: 1139 GSYCEDEVDECSP--NPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGG 1196
Query: 1088 QCVDTINGYTCTCPQGFSGPFCE-----HPPPMVLLQTSPCDQYECQNGAQCIVVQQEPT 1142
C+D N Y C+CP+G G CE PP+ SP +C N C+ T
Sbjct: 1197 TCIDLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSP----KCFNNGTCVDQVGGYT 1252
Query: 1143 CRCPPGFAGPRCE 1155
C CPPGF G RCE
Sbjct: 1253 CTCPPGFVGERCE 1265
Score = 166 bits (416), Expect = 2e-39
Identities = 82/243 (33%), Positives = 113/243 (45%), Gaps = 15/243 (6%)
Query: 918 NACLSSP--CKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDS 975
N C +P C++ GTC + + YRCAC ++ G C +P C +PCQ+GGTC +
Sbjct: 180 NECSQNPGLCRHGGTCHNE-IGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGD 238
Query: 976 HKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVI 1035
C+C GF GQ CVDG+N Y C CPP +TG+ C E +
Sbjct: 239 TTH--ECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDV 296
Query: 1036 DHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095
D C N CQ+ C G++C CV G++G+ C + DDC + C GA C D +
Sbjct: 297 DECQLMPNACQNAGTCHNSHGGYNCVCVNGWTGEDCSDNIDDCASAACFQGATCHDRVAS 356
Query: 1096 YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIV--VQQEPTCRCPPGFAGPR 1153
+ C CP G +G C C C G+ C V + C CP G+ GP
Sbjct: 357 FYCECPHGRTGLLCH--------LNDACISNPCNEGSNCDTNPVNGKAICTCPRGYTGPA 408
Query: 1154 CEK 1156
C +
Sbjct: 409 CSQ 411
Score = 162 bits (406), Expect = 3e-38
Identities = 86/298 (28%), Positives = 128/298 (42%), Gaps = 53/298 (17%)
Query: 900 THRFQC-KGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINT 958
TH C G N + C + CKN G C D V Y C CP + G+ CT ++
Sbjct: 240 THECACLPGFAGQNCEENVDDCPGNNCKNGGACV-DGVNTYNCRCPPEWTGQYCTEDVDE 298
Query: 959 C--IQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGIN 1016
C + N CQ+ GTCH +SH G++C C G+ G+ ATC D +
Sbjct: 299 CQLMPNACQNAGTCH--NSH-GGYNCVCVNGWTGEDCSDNIDDCASAACFQGATCHDRVA 355
Query: 1017 NY---------------------------------------VCICPPNYTGELCDEVIDH 1037
++ +C CP YTG C + +D
Sbjct: 356 SFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPRGYTGPACSQDVDE 415
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C N C+H KC+ F C+C+ GY+G CE D ++C+++ C++ A C+D I +
Sbjct: 416 CALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQ 475
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
C C G+ G +CE + T C C + +C+ E C+CP GF+G C+
Sbjct: 476 CICMPGYEGVYCE-------INTDECASSPCLHNGRCVDKINEFLCQCPKGFSGHLCQ 526
Score = 161 bits (403), Expect = 6e-38
Identities = 88/274 (32%), Positives = 123/274 (44%), Gaps = 22/274 (8%)
Query: 885 SSPEPMADRLLLTTPTHRFQC-KGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCAC 943
++P A + L T + QC +G N C+S+PC+N+ TC D + ++C C
Sbjct: 420 ANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCL-DQIGEFQCIC 478
Query: 944 PYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXX 1003
Y+G C + + C +PC H G C + F C CP GF G
Sbjct: 479 MPGYEGVYCEINTDECASSPCLHNGRC---VDKINEFLCQCPKGFSGHLCQYDVDECAST 535
Query: 1004 XXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPE---LNLCQHEAKCIPLDKGFSC 1060
A C+DG N Y C+C YTG C+ ID C P+ + LC+ F+C
Sbjct: 536 PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHIGLCKDGVAT------FTC 589
Query: 1061 ECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQT 1120
C PGY+G CET+ ++C + CRHG C D N Y C C +G +GP CE +
Sbjct: 590 LCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNYYLCLCLKGTTGPNCE-------INL 642
Query: 1121 SPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
C C +G C+ C C PG+ G C
Sbjct: 643 DDCASNPCDSGT-CLDKIDGYECACEPGYTGSMC 675
Score = 160 bits (400), Expect = 1e-37
Identities = 91/294 (30%), Positives = 123/294 (40%), Gaps = 53/294 (18%)
Query: 903 FQCKGPV---DINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTC 959
F C+ P D +++ N C S+PC + G C +D + Y+C C + G +C + N C
Sbjct: 700 FTCRCPEGYHDPTCLSEVNECNSNPCIH-GAC-RDGLNGYKCDCAPGWSGTNCDINNNEC 757
Query: 960 IQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYV 1019
NPC +GGTC S G+ C+C GF G TC+D + Y
Sbjct: 758 ESNPCVNGGTCKDMTS---GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814
Query: 1020 CICPPNYTGELCDEVIDHCVP-------------------------------ELNL---- 1044
C CP YTG C+ V+ C E+++
Sbjct: 815 CNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECV 874
Query: 1045 ---CQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
C+H A C + + C C GY+G+ CE+D DDC + C +G C D +N C C
Sbjct: 875 KSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCL 934
Query: 1102 QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
GF G FCE + C CQNGA C TC CP GF G CE
Sbjct: 935 PGFQGAFCEE-------DINECATNPCQNGANCTDCVDSYTCTCPTGFNGIHCE 981
Score = 155 bits (389), Expect = 3e-36
Identities = 76/238 (31%), Positives = 110/238 (45%), Gaps = 14/238 (5%)
Query: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
C S+ C TC D V + C CP+ G C + + CI NPC G C + +
Sbjct: 339 CASAACFQGATC-HDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKA 396
Query: 980 FSCSCPLGFEGQRXXXXXXXXXXXXX--XXXATCVDGINNYVCICPPNYTGELCDEVIDH 1037
C+CP G+ G C++ + ++ C C YTG C+ ++
Sbjct: 397 I-CTCPRGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNE 455
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C+ N CQ++A C+ F C C+PGY G CE + D+C + C H +CVD IN +
Sbjct: 456 CIS--NPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEFL 513
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
C CP+GFSG C++ C C+NGA+C+ TC C G+ G CE
Sbjct: 514 CQCPKGFSGHLCQY-------DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Score = 154 bits (386), Expect = 6e-36
Identities = 80/241 (33%), Positives = 109/241 (45%), Gaps = 15/241 (6%)
Query: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
N C S PC++ GTC QD Y C C G +C + ++ C NPC GTC
Sbjct: 605 NECHSQPCRHGGTC-QDRDNYYLCLCLKGTTGPNCEINLDDCASNPCD-SGTCL---DKI 659
Query: 978 DGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDH 1037
DG+ C+C G+ G TC DGI + C CP Y C ++
Sbjct: 660 DGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNE 719
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C N C H A C G+ C+C PG+SG C+ +N++C ++ C +G C D +GY
Sbjct: 720 C--NSNPCIHGA-CRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV 776
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKL 1157
CTC +GFSGP C+ + C C N CI C CP + G CE +
Sbjct: 777 CTCREGFSGPNCQ-------TNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVV 829
Query: 1158 I 1158
+
Sbjct: 830 L 830
Score = 148 bits (371), Expect = 3e-34
Identities = 80/239 (33%), Positives = 106/239 (43%), Gaps = 22/239 (9%)
Query: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
C S+PCKN C P Y C C Y G C V I+ C +PC H G C KDG
Sbjct: 532 CASTPCKNGAKCLDGP-NTYTCVCTEGYTGTHCEVDIDECDPDPC-HIGLC------KDG 583
Query: 980 ---FSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVID 1036
F+C C G+ G TC D N Y+C+C TG C+ +D
Sbjct: 584 VATFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNYYLCLCLKGTTGPNCEINLD 643
Query: 1037 HCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGY 1096
C N C C+ G+ C C PGY+G +C + D+C C +G C D I G+
Sbjct: 644 DCAS--NPCD-SGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGF 700
Query: 1097 TCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
TC CP+G+ P C L + + C+ C +GA C C C PG++G C+
Sbjct: 701 TCRCPEGYHDPTC-------LSEVNECNSNPCIHGA-CRDGLNGYKCDCAPGWSGTNCD 751
Score = 145 bits (363), Expect = 3e-33
Identities = 87/318 (27%), Positives = 125/318 (38%), Gaps = 54/318 (16%)
Query: 883 RCSSPEPMA---DRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC---TQDPV 936
RCS P R + T C G + CLS+PCKN GTC +
Sbjct: 23 RCSQPSGTCLNGGRCEVANGTEACVCSGAFVGQRCQDPSPCLSTPCKNAGTCYVVDHGGI 82
Query: 937 ELYRCACPYSYKGKDCTVPI-NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXX 995
Y C+CP + G C P+ N C+ NPC++GGTC L + + C CP G+ G +
Sbjct: 83 VDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTE--YKCRCPPGWSG-KSCQ 139
Query: 996 XXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKC---- 1051
C+ ++Y+C CPP + G C + ++ C LC+H C
Sbjct: 140 QADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEI 199
Query: 1052 --------------------IPL---------------DKGFSCECVPGYSGKLCETDND 1076
+P D C C+PG++G+ CE + D
Sbjct: 200 GSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVD 259
Query: 1077 DCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIV 1136
DC + C++G CVD +N Y C CP ++G +C L + CQN C
Sbjct: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN-----ACQNAGTCHN 314
Query: 1137 VQQEPTCRCPPGFAGPRC 1154
C C G+ G C
Sbjct: 315 SHGGYNCVCVNGWTGEDC 332
Score = 138 bits (345), Expect = 4e-31
Identities = 95/324 (29%), Positives = 135/324 (41%), Gaps = 38/324 (11%)
Query: 860 HCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCK---GPVDINIVAK 916
+C C + Y E + CS P P + T F CK G N +
Sbjct: 1130 YCHCQAGYTGS-----YCEDEVDECS-PNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEE 1183
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKG-------KDCTVPINTCIQNP-CQHGG 968
N CLS PC+N GTC D Y+C+CP +G DC P++ ++P C + G
Sbjct: 1184 INECLSQPCQNGGTCI-DLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNG 1242
Query: 969 TCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXAT--CVDGINNYVCICPPNY 1026
TC G++C+CP GF G+R T CV +N++ C C +
Sbjct: 1243 TCV---DQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGH 1299
Query: 1027 TGELCDEVIDHCVPELNLCQHEAKCIPLD---KGFSCECVPGYSGKLCETDNDDCVAHKC 1083
TG C+ VI+ C + C++ C +GF C C + G CE D C + +C
Sbjct: 1300 TGRRCESVINGCRGKP--CRNGGVCAVASNTARGFICRCPARFEGATCENDARTCGSLRC 1357
Query: 1084 RHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPC-DQYECQNGAQCIVVQQEP- 1141
+G C+ TC C F+GP C+ P +SPC C N C + P
Sbjct: 1358 LNGGTCISGPRSPTCLCLGSFTGPECQFP------ASSPCVGSNPCYNQGTCEPTSESPF 1411
Query: 1142 -TCRCPPGFAGPRCEKLITVNFVG 1164
C CP F G C ++ +F G
Sbjct: 1412 YRCLCPAKFNGLLCH-ILDYSFTG 1434
Score = 96.3 bits (236), Expect = 2e-18
Identities = 49/143 (34%), Positives = 71/143 (49%), Gaps = 17/143 (11%)
Query: 1020 CICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG----FSCECVPGYSGKLCETD- 1074
C+C + G+ C + C+ C++ C +D G ++C C G+SG LC T
Sbjct: 46 CVCSGAFVGQRCQDP-SPCLS--TPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPL 102
Query: 1075 NDDCVAHKCRHGAQC-VDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQ 1133
+ C+A+ CR+G C + T+ Y C CP G+SG C+ Q PC C NG Q
Sbjct: 103 ANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ--------QADPCASNPCANGGQ 154
Query: 1134 CIVVQQEPTCRCPPGFAGPRCEK 1156
C+ + C CPPGF GP C +
Sbjct: 155 CLPFESSYICGCPPGFHGPTCRQ 177
Score = 76.5 bits (185), Expect = 2e-12
Identities = 42/125 (33%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYM 1390
CK+ VCK S + +S C C GW G C+ + + C+ C HG C T SY
Sbjct: 838 CKNSGVCKE----SEDYESFSCVCPTGWQGQTCEIDINE-CVKSPCRHGASCQNTNGSYR 892
Query: 1391 CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE---- 1446
C C GY G C++ D C CH+G +C C PGF G C+++
Sbjct: 893 CLCQAGYTGRNCESDIDD---CRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINEC 949
Query: 1447 --NPC 1449
NPC
Sbjct: 950 ATNPC 954
Score = 74.9 bits (181), Expect = 6e-12
Identities = 37/107 (34%), Positives = 55/107 (50%), Gaps = 11/107 (10%)
Query: 1352 VCECRPGWTGPLCDQEARDPCLG-HRCHH-GKCVATGTSYMCKCAEGYGGDLCDNKNDSA 1409
+C C G+TGP C Q+ + LG + C H GKC+ T S+ C+C +GY G C+
Sbjct: 397 ICTCPRGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCE---IDV 453
Query: 1410 NACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ------QENPCL 1450
N C + C + + GE C+C PG+ G +C+ +PCL
Sbjct: 454 NECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCL 500
Score = 74.1 bits (179), Expect = 1e-11
Identities = 45/127 (35%), Positives = 60/127 (46%), Gaps = 10/127 (7%)
Query: 1332 CKSCTVCKHGLCRSVEK-DSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSY 1389
C S +G C V+K + +C+C G++G LC + D C C +G KC+ +Y
Sbjct: 494 CASSPCLHNGRC--VDKINEFLCQCPKGFSGHLCQYDV-DECASTPCKNGAKCLDGPNTY 550
Query: 1390 MCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NP 1448
C C EGY G C+ D C CH G C CLCQPG++G HC+ N
Sbjct: 551 TCVCTEGYTGTHCEVDIDE---CDPDPCHIGLCK-DGVATFTCLCQPGYTGHHCETNINE 606
Query: 1449 CLGQVVR 1455
C Q R
Sbjct: 607 CHSQPCR 613
Score = 69.1 bits (166), Expect = 4e-10
Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 7/123 (5%)
Query: 1326 LGVSPGCKSCTV--CKHG-LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-K 1381
L ++P +C C++G C + C C PGW+G C Q DPC + C +G +
Sbjct: 97 LCLTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA--DPCASNPCANGGQ 154
Query: 1382 CVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGE 1441
C+ +SY+C C G+ G C + + H G CH ++ G C C+ +G
Sbjct: 155 CLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCH-NEIGSYRCACRATHTGP 213
Query: 1442 HCQ 1444
HC+
Sbjct: 214 HCE 216
Score = 68.7 bits (165), Expect = 5e-10
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEG 1396
C +G + ++ C+C PG+ G C+++ + C + C +G C SY C C G
Sbjct: 916 CHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINE-CATNPCQNGANCTDCVDSYTCTCPTG 974
Query: 1397 YGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPCL 1450
+ G C+N C+ C +G + CLC PGF+G +CQ + PCL
Sbjct: 975 FNGIHCENNTPD---CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCL 1031
Score = 68.7 bits (165), Expect = 5e-10
Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 1336 TVCKH-GLCRSVEKDSVV---CECRPGWTGPLCDQEARDPCLGHRCHHGKC--VATGTSY 1389
T CK+ G C V+ +V C C G++GPLC + CL + C +G + T T Y
Sbjct: 66 TPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTEY 125
Query: 1390 MCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NP 1448
C+C G+ G C A+ C++ C +G + + C C PGF G C+Q+ N
Sbjct: 126 KCRCPPGWSGKSCQQ----ADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNE 181
Query: 1449 C 1449
C
Sbjct: 182 C 182
Score = 67.9 bits (163), Expect = 8e-10
Identities = 42/128 (32%), Positives = 53/128 (40%), Gaps = 18/128 (14%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMC 1391
C + C+ G+ C C G+ P C E + C + C HG C Y C
Sbjct: 687 CHNGGTCEDGIA------GFTCRCPEGYHDPTCLSEVNE-CNSNPCIHGACRDGLNGYKC 739
Query: 1392 KCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISDQGEPYCLCQPGFSGEHCQ------ 1444
CA G+ G CD N N C + C + G C G C C+ GFSG +CQ
Sbjct: 740 DCAPGWSGTNCDINN---NECESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINEC 795
Query: 1445 QENPCLGQ 1452
NPCL Q
Sbjct: 796 ASNPCLNQ 803
Score = 67.5 bits (162), Expect = 1e-09
Identities = 40/132 (30%), Positives = 55/132 (41%), Gaps = 16/132 (12%)
Query: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVA----TGTSYMCKCAEGYGGDLCDNKNDS 1408
CECR G TG C+ C G C +G A T ++C+C + G C+N
Sbjct: 1293 CECRAGHTGRRCESVING-CRGKPCRNGGVCAVASNTARGFICRCPARFEGATCEN---D 1348
Query: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ--QENPCLGQVVREVIRRQKGYAS 1466
A C + +C +G IS P CLC F+G CQ +PC+G +
Sbjct: 1349 ARTCGSLRCLNGGTCISGPRSPTCLCLGSFTGPECQFPASSPCVGS------NPCYNQGT 1402
Query: 1467 CATASKVPIMEC 1478
C S+ P C
Sbjct: 1403 CEPTSESPFYRC 1414
Score = 66.7 bits (160), Expect = 2e-09
Identities = 45/165 (27%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 1290 ALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCK----SC--TVCKHGLC 1343
A Q D G + C H + N L F+ Q P C+ C C++
Sbjct: 408 ACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGY-TGPRCEIDVNECISNPCQNDAT 466
Query: 1344 RSVEKDSVVCECRPGWTGPLC----DQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGG 1399
+ C C PG+ G C D+ A PCL H+G+CV ++C+C +G+ G
Sbjct: 467 CLDQIGEFQCICMPGYEGVYCEINTDECASSPCL----HNGRCVDKINEFLCQCPKGFSG 522
Query: 1400 DLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
LC D C++ C +G + C+C G++G HC+
Sbjct: 523 HLCQYDVDE---CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Score = 66.7 bits (160), Expect = 2e-09
Identities = 39/126 (30%), Positives = 55/126 (42%), Gaps = 15/126 (11%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEG 1396
C HG + C C G+TG C R C C +G KC T T Y C+C G
Sbjct: 1030 CLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRW-CDSAPCKNGGKCWQTNTQYHCECRSG 1088
Query: 1397 YGGDLCDNKNDSANACSAFK-------CHHGQCHISDQGEPYCLCQPGFSGEHCQQE--- 1446
+ G CD + S + + C HG + ++ + YC CQ G++G +C+ E
Sbjct: 1089 WTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDE 1148
Query: 1447 ---NPC 1449
NPC
Sbjct: 1149 CSPNPC 1154
Score = 66.7 bits (160), Expect = 2e-09
Identities = 38/112 (33%), Positives = 52/112 (45%), Gaps = 11/112 (9%)
Query: 1337 VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYM----CK 1392
+C+HG E+D C C+ G+TG C+ E D C + C +G AT T Y+ CK
Sbjct: 1115 LCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEV-DECSPNPCQNG---ATCTDYLGGFSCK 1170
Query: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
C GY G C ++ N C + C +G I C C G G HC+
Sbjct: 1171 CVAGYHGSNC---SEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCE 1219
Score = 66.0 bits (158), Expect = 3e-09
Identities = 40/118 (33%), Positives = 51/118 (42%), Gaps = 10/118 (8%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVATG----TSYMCK 1392
C +G V + C C + G C + PCL C + G C Y C
Sbjct: 31 CLNGGRCEVANGTEACVCSGAFVGQRCQDPS--PCLSTPCKNAGTCYVVDHGGIVDYACS 88
Query: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQENPC 1449
C G+ G LC ANAC A C +G C + E C C PG+SG+ CQQ +PC
Sbjct: 89 CPLGFSGPLC--LTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPC 144
Score = 64.0 bits (153), Expect = 1e-08
Identities = 48/165 (29%), Positives = 62/165 (37%), Gaps = 21/165 (12%)
Query: 1305 CIHEVRINNELQDFKALPPQSL------GVSPGCKSCTVCKHGLCRSVEKDSVVCECRPG 1358
C+H + +K PQ + C S CK+G CECR G
Sbjct: 1030 CLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAP-CKNGGKCWQTNTQYHCECRSG 1088
Query: 1359 WTGPLCD---------QEARDPCLGHRCHHGK-CVATGTSYMCKCAEGYGGDLCDNKNDS 1408
WTG CD + R + C HG CV + C C GY G C+ D
Sbjct: 1089 WTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCE---DE 1145
Query: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPCLGQ 1452
+ CS C +G G C C G+ G +C +E N CL Q
Sbjct: 1146 VDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQ 1190
Score = 63.2 bits (151), Expect = 2e-08
Identities = 37/131 (28%), Positives = 52/131 (39%), Gaps = 10/131 (7%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGY 1397
C+HG + +C C G TGP C+ D C + C G C+ Y C C GY
Sbjct: 612 CRHGGTCQDRDNYYLCLCLKGTTGPNCEINL-DDCASNPCDSGTCLDKIDGYECACEPGY 670
Query: 1398 GGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPCLG 1451
G +C N + + C+ CH+G C C G+ C E NPC+
Sbjct: 671 TGSMC---NVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIH 727
Query: 1452 QVVREVIRRQK 1462
R+ + K
Sbjct: 728 GACRDGLNGYK 738
Score = 62.5 bits (149), Expect = 4e-08
Identities = 43/151 (28%), Positives = 67/151 (43%), Gaps = 19/151 (12%)
Query: 1305 CIHEVRINNELQDFKALPPQSLGVSPGCK------SCTVCKHG-LCRSVEKDSVVCECRP 1357
C H +NE+ ++ ++ P C+ S + C++G CR + C C P
Sbjct: 189 CRHGGTCHNEIGSYRCAC-RATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLP 247
Query: 1358 GWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLCDNKNDSA----NAC 1412
G+ G C++ D C G+ C +G CV +Y C+C + G C D NAC
Sbjct: 248 GFAGQNCEENV-DDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 1413 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443
+ G CH + G C+C G++GE C
Sbjct: 307 Q----NAGTCH-NSHGGYNCVCVNGWTGEDC 332
Score = 62.1 bits (148), Expect = 5e-08
Identities = 39/125 (31%), Positives = 60/125 (47%), Gaps = 16/125 (12%)
Query: 1325 SLGVSPGCKSCTVCKH-GLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKC 1382
+LG +P C+H G C + S C+C G+TGP C+ + + C+ + C + C
Sbjct: 417 ALGANP-------CEHAGKCLNT-LGSFECQCLQGYTGPRCEIDVNE-CISNPCQNDATC 467
Query: 1383 VATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISDQGEPYCLCQPGFSGE 1441
+ + C C GY G C+ D C++ C H+G+C + E C C GFSG
Sbjct: 468 LDQIGEFQCICMPGYEGVYCEINTDE---CASSPCLHNGRC-VDKINEFLCQCPKGFSGH 523
Query: 1442 HCQQE 1446
CQ +
Sbjct: 524 LCQYD 528
Score = 58.9 bits (140), Expect = 4e-07
Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 6/112 (5%)
Query: 1337 VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATG-TSYMCKCA 1394
+C+HG E S C CR TGP C+ PC C +G C TG T++ C C
Sbjct: 188 LCRHGGTCHNEIGSYRCACRATHTGPHCELPYV-PCSPSPCQNGGTCRPTGDTTHECACL 246
Query: 1395 EGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE 1446
G+ G C+ D C C +G + C C P ++G++C ++
Sbjct: 247 PGFAGQNCEENVDD---CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTED 295
Score = 58.2 bits (138), Expect = 7e-07
Identities = 42/164 (25%), Positives = 63/164 (37%), Gaps = 50/164 (30%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLC----DQEARDPCL----------GHRC 1377
C+S G C+ + VC CR G++GP C ++ A +PCL G++C
Sbjct: 757 CESNPCVNGGTCKDMTS-GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC 815
Query: 1378 H------------------HGKCVATGT--------SYMCKCAEGYGGDLCDNKNDSANA 1411
+ C +G S+ C C G+ G C+ N
Sbjct: 816 NCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCE---IDINE 872
Query: 1412 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPC 1449
C C HG + G CLCQ G++G +C+ + NPC
Sbjct: 873 CVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPC 916
Score = 57.0 bits (135), Expect = 2e-06
Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEG 1396
C++G + DS C C G+ G C+ D C C +G CV S+ C C G
Sbjct: 954 CQNGANCTDCVDSYTCTCPTGFNGIHCENNTPD-CTESSCFNGGTCVDGINSFTCLCPPG 1012
Query: 1397 YGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
+ G C N C + C HG G C C G++G +CQ
Sbjct: 1013 FTGSYCQY---DVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQ 1057
Score = 55.4 bits (131), Expect = 5e-06
Identities = 40/165 (24%), Positives = 63/165 (37%), Gaps = 54/165 (32%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPC--LGHRCHH-GKCVATGTS 1388
CK+ C G+ ++ C C P WTG C ++ D C + + C + G C +
Sbjct: 266 CKNGGACVDGV------NTYNCRCPPEWTGQYCTEDV-DECQLMPNACQNAGTCHNSHGG 318
Query: 1389 YMCKCAEGYGGDLCDNKNDSANACSAF--------------KCHHGQ----CHISD---- 1426
Y C C G+ G+ C + D + + F +C HG+ CH++D
Sbjct: 319 YNCVCVNGWTGEDCSDNIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Query: 1427 --------------QGEPYCLCQPGFSGEHCQQE--------NPC 1449
G+ C C G++G C Q+ NPC
Sbjct: 379 NPCNEGSNCDTNPVNGKAICTCPRGYTGPACSQDVDECALGANPC 423
Score = 41.4 bits (95), Expect = 0.076
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLG-HRCHH-GKCVATGTS- 1388
C S G C S + S C C +TGP C A PC+G + C++ G C T S
Sbjct: 1352 CGSLRCLNGGTCISGPR-SPTCLCLGSFTGPECQFPASSPCVGSNPCYNQGTCEPTSESP 1410
Query: 1389 -YMCKCAEGYGGDLC 1402
Y C C + G LC
Sbjct: 1411 FYRCLCPAKFNGLLC 1425
>pir||S18188 notch protein homolog - rat
Length = 2531
Score = 199 bits (501), Expect = 2e-49
Identities = 103/301 (34%), Positives = 137/301 (45%), Gaps = 14/301 (4%)
Query: 855 GTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIV 914
G N CDC+ W E C + D T R GP N
Sbjct: 733 GLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP---NCQ 789
Query: 915 AKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSD 974
N C S+PC N GTC D V Y+C CP Y G C V + C +PC++ G C S+
Sbjct: 790 TNINECASNPCLNQGTCIDD-VAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESE 848
Query: 975 SHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEV 1034
+ + FSC CP G++GQ A+C + +Y C+C YTG C+
Sbjct: 849 DY-ESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESD 907
Query: 1035 IDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTIN 1094
ID C P N C + C C+C+PG+ G CE D ++C + C++GA C D ++
Sbjct: 908 IDDCRP--NPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINECATNPCQNGANCTDCVD 965
Query: 1095 GYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
YTCTCP GF+G CE+ T C + C NG C+ TC CPPGF G C
Sbjct: 966 SYTCTCPTGFNGIHCEN-------NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
Query: 1155 E 1155
+
Sbjct: 1019 Q 1019
Score = 180 bits (451), Expect = 1e-43
Identities = 78/240 (32%), Positives = 119/240 (49%), Gaps = 13/240 (5%)
Query: 920 CLSSPCKNNGTCTQ-DPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKD 978
C +SPCKN+G C + + E + C CP ++G+ C + IN C+++PC+HG +C ++
Sbjct: 833 CATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECVKSPCRHGASCQNTNG--- 889
Query: 979 GFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHC 1038
+ C C G+ G+ +C DG+N C C P + G C+E I+ C
Sbjct: 890 SYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINEC 949
Query: 1039 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTC 1098
N CQ+ A C ++C C G++G CE + DC C +G CVD IN +TC
Sbjct: 950 AT--NPCQNGANCTDCVDSYTCTCPTGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTC 1007
Query: 1099 TCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
CP GF+G +C++ + CD C +G C C CP G+ G C+ L+
Sbjct: 1008 LCPPGFTGSYCQY-------DVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLV 1060
Score = 168 bits (421), Expect = 4e-40
Identities = 86/253 (33%), Positives = 118/253 (45%), Gaps = 25/253 (9%)
Query: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
N C S PC + GTC QD Y+C CP Y G +C + C PC++GG C +++
Sbjct: 1023 NECDSRPCLHGGTC-QDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGKCWQTNTQ- 1080
Query: 978 DGFSCSCPLGFEG----------QRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYT 1027
+ C C G+ G + CVD + + C C YT
Sbjct: 1081 --YHCECRSGWTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYT 1138
Query: 1028 GELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGA 1087
G C++ +D C P N CQ+ A C GFSC+CV GY G C + ++C++ C++G
Sbjct: 1139 GSYCEDEVDECSP--NPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGG 1196
Query: 1088 QCVDTINGYTCTCPQGFSGPFCE-----HPPPMVLLQTSPCDQYECQNGAQCIVVQQEPT 1142
C+D N Y C+CP+G G CE PP+ SP +C N C+ T
Sbjct: 1197 TCIDLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSP----KCFNNGTCVDQVGGYT 1252
Query: 1143 CRCPPGFAGPRCE 1155
C CPPGF G RCE
Sbjct: 1253 CTCPPGFVGERCE 1265
Score = 166 bits (416), Expect = 2e-39
Identities = 82/243 (33%), Positives = 113/243 (45%), Gaps = 15/243 (6%)
Query: 918 NACLSSP--CKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDS 975
N C +P C++ GTC + + YRCAC ++ G C +P C +PCQ+GGTC +
Sbjct: 180 NECSQNPGLCRHGGTCHNE-IGSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGD 238
Query: 976 HKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVI 1035
C+C GF GQ CVDG+N Y C CPP +TG+ C E +
Sbjct: 239 TTH--ECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDV 296
Query: 1036 DHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095
D C N CQ+ C G++C CV G++G+ C + DDC + C GA C D +
Sbjct: 297 DECQLMPNACQNAGTCHNSHGGYNCVCVNGWTGEDCSDNIDDCASAACFQGATCHDRVAS 356
Query: 1096 YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIV--VQQEPTCRCPPGFAGPR 1153
+ C CP G +G C C C G+ C V + C CP G+ GP
Sbjct: 357 FYCECPHGRTGLLCH--------LNDACISNPCNEGSNCDTNPVNGKAICTCPRGYTGPA 408
Query: 1154 CEK 1156
C +
Sbjct: 409 CSQ 411
Score = 162 bits (406), Expect = 3e-38
Identities = 86/298 (28%), Positives = 128/298 (42%), Gaps = 53/298 (17%)
Query: 900 THRFQC-KGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINT 958
TH C G N + C + CKN G C D V Y C CP + G+ CT ++
Sbjct: 240 THECACLPGFAGQNCEENVDDCPGNNCKNGGACV-DGVNTYNCRCPPEWTGQYCTEDVDE 298
Query: 959 C--IQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGIN 1016
C + N CQ+ GTCH +SH G++C C G+ G+ ATC D +
Sbjct: 299 CQLMPNACQNAGTCH--NSH-GGYNCVCVNGWTGEDCSDNIDDCASAACFQGATCHDRVA 355
Query: 1017 NY---------------------------------------VCICPPNYTGELCDEVIDH 1037
++ +C CP YTG C + +D
Sbjct: 356 SFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPRGYTGPACSQDVDE 415
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C N C+H KC+ F C+C+ GY+G CE D ++C+++ C++ A C+D I +
Sbjct: 416 CALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCLDQIGEFQ 475
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
C C G+ G +CE + T C C + +C+ E C+CP GF+G C+
Sbjct: 476 CICMPGYEGVYCE-------INTDECASSPCLHNGRCVDKINEFLCQCPKGFSGHLCQ 526
Score = 161 bits (403), Expect = 6e-38
Identities = 88/274 (32%), Positives = 123/274 (44%), Gaps = 22/274 (8%)
Query: 885 SSPEPMADRLLLTTPTHRFQC-KGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCAC 943
++P A + L T + QC +G N C+S+PC+N+ TC D + ++C C
Sbjct: 420 ANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECISNPCQNDATCL-DQIGEFQCIC 478
Query: 944 PYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXX 1003
Y+G C + + C +PC H G C + F C CP GF G
Sbjct: 479 MPGYEGVYCEINTDECASSPCLHNGRC---VDKINEFLCQCPKGFSGHLCQYDVDECAST 535
Query: 1004 XXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPE---LNLCQHEAKCIPLDKGFSC 1060
A C+DG N Y C+C YTG C+ ID C P+ + LC+ F+C
Sbjct: 536 PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHIGLCKDGVAT------FTC 589
Query: 1061 ECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQT 1120
C PGY+G CET+ ++C + CRHG C D N Y C C +G +GP CE +
Sbjct: 590 LCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNYYLCLCLKGTTGPNCE-------INL 642
Query: 1121 SPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
C C +G C+ C C PG+ G C
Sbjct: 643 DDCASNPCDSGT-CLDKIDGYECACEPGYTGSMC 675
Score = 160 bits (400), Expect = 1e-37
Identities = 91/294 (30%), Positives = 123/294 (40%), Gaps = 53/294 (18%)
Query: 903 FQCKGPV---DINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTC 959
F C+ P D +++ N C S+PC + G C +D + Y+C C + G +C + N C
Sbjct: 700 FTCRCPEGYHDPTCLSEVNECNSNPCIH-GAC-RDGLNGYKCDCAPGWSGTNCDINNNEC 757
Query: 960 IQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYV 1019
NPC +GGTC S G+ C+C GF G TC+D + Y
Sbjct: 758 ESNPCVNGGTCKDMTS---GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814
Query: 1020 CICPPNYTGELCDEVIDHCVP-------------------------------ELNL---- 1044
C CP YTG C+ V+ C E+++
Sbjct: 815 CNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEIDINECV 874
Query: 1045 ---CQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
C+H A C + + C C GY+G+ CE+D DDC + C +G C D +N C C
Sbjct: 875 KSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGVNAAFCDCL 934
Query: 1102 QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
GF G FCE + C CQNGA C TC CP GF G CE
Sbjct: 935 PGFQGAFCEE-------DINECATNPCQNGANCTDCVDSYTCTCPTGFNGIHCE 981
Score = 155 bits (389), Expect = 3e-36
Identities = 76/238 (31%), Positives = 110/238 (45%), Gaps = 14/238 (5%)
Query: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
C S+ C TC D V + C CP+ G C + + CI NPC G C + +
Sbjct: 339 CASAACFQGATC-HDRVASFYCECPHGRTGLLCHLN-DACISNPCNEGSNCDTNPVNGKA 396
Query: 980 FSCSCPLGFEGQRXXXXXXXXXXXXX--XXXATCVDGINNYVCICPPNYTGELCDEVIDH 1037
C+CP G+ G C++ + ++ C C YTG C+ ++
Sbjct: 397 I-CTCPRGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNE 455
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C+ N CQ++A C+ F C C+PGY G CE + D+C + C H +CVD IN +
Sbjct: 456 CIS--NPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGRCVDKINEFL 513
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
C CP+GFSG C++ C C+NGA+C+ TC C G+ G CE
Sbjct: 514 CQCPKGFSGHLCQY-------DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Score = 154 bits (386), Expect = 6e-36
Identities = 80/241 (33%), Positives = 109/241 (45%), Gaps = 15/241 (6%)
Query: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
N C S PC++ GTC QD Y C C G +C + ++ C NPC GTC
Sbjct: 605 NECHSQPCRHGGTC-QDRDNYYLCLCLKGTTGPNCEINLDDCASNPCD-SGTCL---DKI 659
Query: 978 DGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDH 1037
DG+ C+C G+ G TC DGI + C CP Y C ++
Sbjct: 660 DGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNE 719
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C N C H A C G+ C+C PG+SG C+ +N++C ++ C +G C D +GY
Sbjct: 720 C--NSNPCIHGA-CRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV 776
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKL 1157
CTC +GFSGP C+ + C C N CI C CP + G CE +
Sbjct: 777 CTCREGFSGPNCQ-------TNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVV 829
Query: 1158 I 1158
+
Sbjct: 830 L 830
Score = 148 bits (371), Expect = 3e-34
Identities = 80/239 (33%), Positives = 106/239 (43%), Gaps = 22/239 (9%)
Query: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
C S+PCKN C P Y C C Y G C V I+ C +PC H G C KDG
Sbjct: 532 CASTPCKNGAKCLDGP-NTYTCVCTEGYTGTHCEVDIDECDPDPC-HIGLC------KDG 583
Query: 980 ---FSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVID 1036
F+C C G+ G TC D N Y+C+C TG C+ +D
Sbjct: 584 VATFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNYYLCLCLKGTTGPNCEINLD 643
Query: 1037 HCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGY 1096
C N C C+ G+ C C PGY+G +C + D+C C +G C D I G+
Sbjct: 644 DCAS--NPCD-SGTCLDKIDGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGF 700
Query: 1097 TCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
TC CP+G+ P C L + + C+ C +GA C C C PG++G C+
Sbjct: 701 TCRCPEGYHDPTC-------LSEVNECNSNPCIHGA-CRDGLNGYKCDCAPGWSGTNCD 751
Score = 145 bits (363), Expect = 3e-33
Identities = 87/318 (27%), Positives = 125/318 (38%), Gaps = 54/318 (16%)
Query: 883 RCSSPEPMA---DRLLLTTPTHRFQCKGPVDINIVAKCNACLSSPCKNNGTC---TQDPV 936
RCS P R + T C G + CLS+PCKN GTC +
Sbjct: 23 RCSQPSGTCLNGGRCEVANGTEACVCSGAFVGQRCQDPSPCLSTPCKNAGTCYVVDHGGI 82
Query: 937 ELYRCACPYSYKGKDCTVPI-NTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXX 995
Y C+CP + G C P+ N C+ NPC++GGTC L + + C CP G+ G +
Sbjct: 83 VDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTE--YKCRCPPGWSG-KSCQ 139
Query: 996 XXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKC---- 1051
C+ ++Y+C CPP + G C + ++ C LC+H C
Sbjct: 140 QADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCHNEI 199
Query: 1052 --------------------IPL---------------DKGFSCECVPGYSGKLCETDND 1076
+P D C C+PG++G+ CE + D
Sbjct: 200 GSYRCACRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLPGFAGQNCEENVD 259
Query: 1077 DCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIV 1136
DC + C++G CVD +N Y C CP ++G +C L + CQN C
Sbjct: 260 DCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPN-----ACQNAGTCHN 314
Query: 1137 VQQEPTCRCPPGFAGPRC 1154
C C G+ G C
Sbjct: 315 SHGGYNCVCVNGWTGEDC 332
Score = 138 bits (345), Expect = 4e-31
Identities = 95/324 (29%), Positives = 135/324 (41%), Gaps = 38/324 (11%)
Query: 860 HCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCK---GPVDINIVAK 916
+C C + Y E + CS P P + T F CK G N +
Sbjct: 1130 YCHCQAGYTGS-----YCEDEVDECS-PNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEE 1183
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKG-------KDCTVPINTCIQNP-CQHGG 968
N CLS PC+N GTC D Y+C+CP +G DC P++ ++P C + G
Sbjct: 1184 INECLSQPCQNGGTCI-DLTNTYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNG 1242
Query: 969 TCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXAT--CVDGINNYVCICPPNY 1026
TC G++C+CP GF G+R T CV +N++ C C +
Sbjct: 1243 TCV---DQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGH 1299
Query: 1027 TGELCDEVIDHCVPELNLCQHEAKCIPLD---KGFSCECVPGYSGKLCETDNDDCVAHKC 1083
TG C+ VI+ C + C++ C +GF C C + G CE D C + +C
Sbjct: 1300 TGRRCESVINGCRGKP--CRNGGVCAVASNTARGFICRCPARFEGATCENDARTCGSLRC 1357
Query: 1084 RHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPC-DQYECQNGAQCIVVQQEP- 1141
+G C+ TC C F+GP C+ P +SPC C N C + P
Sbjct: 1358 LNGGTCISGPRSPTCLCLGSFTGPECQFP------ASSPCVGSNPCYNQGTCEPTSESPF 1411
Query: 1142 -TCRCPPGFAGPRCEKLITVNFVG 1164
C CP F G C ++ +F G
Sbjct: 1412 YRCLCPAKFNGLLCH-ILDYSFTG 1434
Score = 96.3 bits (236), Expect = 2e-18
Identities = 49/143 (34%), Positives = 71/143 (49%), Gaps = 17/143 (11%)
Query: 1020 CICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG----FSCECVPGYSGKLCETD- 1074
C+C + G+ C + C+ C++ C +D G ++C C G+SG LC T
Sbjct: 46 CVCSGAFVGQRCQDP-SPCLS--TPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPL 102
Query: 1075 NDDCVAHKCRHGAQC-VDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQ 1133
+ C+A+ CR+G C + T+ Y C CP G+SG C+ Q PC C NG Q
Sbjct: 103 ANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQ--------QADPCASNPCANGGQ 154
Query: 1134 CIVVQQEPTCRCPPGFAGPRCEK 1156
C+ + C CPPGF GP C +
Sbjct: 155 CLPFESSYICGCPPGFHGPTCRQ 177
Score = 76.5 bits (185), Expect = 2e-12
Identities = 42/125 (33%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYM 1390
CK+ VCK S + +S C C GW G C+ + + C+ C HG C T SY
Sbjct: 838 CKNSGVCKE----SEDYESFSCVCPTGWQGQTCEIDINE-CVKSPCRHGASCQNTNGSYR 892
Query: 1391 CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE---- 1446
C C GY G C++ D C CH+G +C C PGF G C+++
Sbjct: 893 CLCQAGYTGRNCESDIDD---CRPNPCHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINEC 949
Query: 1447 --NPC 1449
NPC
Sbjct: 950 ATNPC 954
Score = 74.9 bits (181), Expect = 6e-12
Identities = 37/107 (34%), Positives = 55/107 (50%), Gaps = 11/107 (10%)
Query: 1352 VCECRPGWTGPLCDQEARDPCLG-HRCHH-GKCVATGTSYMCKCAEGYGGDLCDNKNDSA 1409
+C C G+TGP C Q+ + LG + C H GKC+ T S+ C+C +GY G C+
Sbjct: 397 ICTCPRGYTGPACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGYTGPRCE---IDV 453
Query: 1410 NACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ------QENPCL 1450
N C + C + + GE C+C PG+ G +C+ +PCL
Sbjct: 454 NECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCL 500
Score = 74.1 bits (179), Expect = 1e-11
Identities = 45/127 (35%), Positives = 60/127 (46%), Gaps = 10/127 (7%)
Query: 1332 CKSCTVCKHGLCRSVEK-DSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSY 1389
C S +G C V+K + +C+C G++G LC + D C C +G KC+ +Y
Sbjct: 494 CASSPCLHNGRC--VDKINEFLCQCPKGFSGHLCQYDV-DECASTPCKNGAKCLDGPNTY 550
Query: 1390 MCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NP 1448
C C EGY G C+ D C CH G C CLCQPG++G HC+ N
Sbjct: 551 TCVCTEGYTGTHCEVDIDE---CDPDPCHIGLCK-DGVATFTCLCQPGYTGHHCETNINE 606
Query: 1449 CLGQVVR 1455
C Q R
Sbjct: 607 CHSQPCR 613
Score = 69.1 bits (166), Expect = 4e-10
Identities = 37/123 (30%), Positives = 58/123 (47%), Gaps = 7/123 (5%)
Query: 1326 LGVSPGCKSCTV--CKHG-LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-K 1381
L ++P +C C++G C + C C PGW+G C Q DPC + C +G +
Sbjct: 97 LCLTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA--DPCASNPCANGGQ 154
Query: 1382 CVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGE 1441
C+ +SY+C C G+ G C + + H G CH ++ G C C+ +G
Sbjct: 155 CLPFESSYICGCPPGFHGPTCRQDVNECSQNPGLCRHGGTCH-NEIGSYRCACRATHTGP 213
Query: 1442 HCQ 1444
HC+
Sbjct: 214 HCE 216
Score = 68.7 bits (165), Expect = 5e-10
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 11/120 (9%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEG 1396
C +G + ++ C+C PG+ G C+++ + C + C +G C SY C C G
Sbjct: 916 CHNGGSCTDGVNAAFCDCLPGFQGAFCEEDINE-CATNPCQNGANCTDCVDSYTCTCPTG 974
Query: 1397 YGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPCL 1450
+ G C+N C+ C +G + CLC PGF+G +CQ + PCL
Sbjct: 975 FNGIHCENNTPD---CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCL 1031
Score = 68.7 bits (165), Expect = 5e-10
Identities = 40/121 (33%), Positives = 59/121 (48%), Gaps = 11/121 (9%)
Query: 1336 TVCKH-GLCRSVEKDSVV---CECRPGWTGPLCDQEARDPCLGHRCHHGKC--VATGTSY 1389
T CK+ G C V+ +V C C G++GPLC + CL + C +G + T T Y
Sbjct: 66 TPCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPLANACLANPCRNGGTCDLLTLTEY 125
Query: 1390 MCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NP 1448
C+C G+ G C A+ C++ C +G + + C C PGF G C+Q+ N
Sbjct: 126 KCRCPPGWSGKSCQQ----ADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNE 181
Query: 1449 C 1449
C
Sbjct: 182 C 182
Score = 67.9 bits (163), Expect = 8e-10
Identities = 42/128 (32%), Positives = 53/128 (40%), Gaps = 18/128 (14%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMC 1391
C + C+ G+ C C G+ P C E + C + C HG C Y C
Sbjct: 687 CHNGGTCEDGIA------GFTCRCPEGYHDPTCLSEVNE-CNSNPCIHGACRDGLNGYKC 739
Query: 1392 KCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISDQGEPYCLCQPGFSGEHCQ------ 1444
CA G+ G CD N N C + C + G C G C C+ GFSG +CQ
Sbjct: 740 DCAPGWSGTNCDINN---NECESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINEC 795
Query: 1445 QENPCLGQ 1452
NPCL Q
Sbjct: 796 ASNPCLNQ 803
Score = 67.5 bits (162), Expect = 1e-09
Identities = 40/132 (30%), Positives = 55/132 (41%), Gaps = 16/132 (12%)
Query: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVA----TGTSYMCKCAEGYGGDLCDNKNDS 1408
CECR G TG C+ C G C +G A T ++C+C + G C+N
Sbjct: 1293 CECRAGHTGRRCESVING-CRGKPCRNGGVCAVASNTARGFICRCPARFEGATCEN---D 1348
Query: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ--QENPCLGQVVREVIRRQKGYAS 1466
A C + +C +G IS P CLC F+G CQ +PC+G +
Sbjct: 1349 ARTCGSLRCLNGGTCISGPRSPTCLCLGSFTGPECQFPASSPCVGS------NPCYNQGT 1402
Query: 1467 CATASKVPIMEC 1478
C S+ P C
Sbjct: 1403 CEPTSESPFYRC 1414
Score = 66.7 bits (160), Expect = 2e-09
Identities = 45/165 (27%), Positives = 69/165 (41%), Gaps = 18/165 (10%)
Query: 1290 ALRQGTDRPLGGFHGCIHEVRINNELQDFKALPPQSLGVSPGCK----SC--TVCKHGLC 1343
A Q D G + C H + N L F+ Q P C+ C C++
Sbjct: 408 ACSQDVDECALGANPCEHAGKCLNTLGSFECQCLQGY-TGPRCEIDVNECISNPCQNDAT 466
Query: 1344 RSVEKDSVVCECRPGWTGPLC----DQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGG 1399
+ C C PG+ G C D+ A PCL H+G+CV ++C+C +G+ G
Sbjct: 467 CLDQIGEFQCICMPGYEGVYCEINTDECASSPCL----HNGRCVDKINEFLCQCPKGFSG 522
Query: 1400 DLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
LC D C++ C +G + C+C G++G HC+
Sbjct: 523 HLCQYDVDE---CASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Score = 66.7 bits (160), Expect = 2e-09
Identities = 39/126 (30%), Positives = 55/126 (42%), Gaps = 15/126 (11%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEG 1396
C HG + C C G+TG C R C C +G KC T T Y C+C G
Sbjct: 1030 CLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRW-CDSAPCKNGGKCWQTNTQYHCECRSG 1088
Query: 1397 YGGDLCDNKNDSANACSAFK-------CHHGQCHISDQGEPYCLCQPGFSGEHCQQE--- 1446
+ G CD + S + + C HG + ++ + YC CQ G++G +C+ E
Sbjct: 1089 WTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEVDE 1148
Query: 1447 ---NPC 1449
NPC
Sbjct: 1149 CSPNPC 1154
Score = 66.7 bits (160), Expect = 2e-09
Identities = 38/112 (33%), Positives = 52/112 (45%), Gaps = 11/112 (9%)
Query: 1337 VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYM----CK 1392
+C+HG E+D C C+ G+TG C+ E D C + C +G AT T Y+ CK
Sbjct: 1115 LCQHGGLCVDEEDKHYCHCQAGYTGSYCEDEV-DECSPNPCQNG---ATCTDYLGGFSCK 1170
Query: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
C GY G C ++ N C + C +G I C C G G HC+
Sbjct: 1171 CVAGYHGSNC---SEEINECLSQPCQNGGTCIDLTNTYKCSCPRGTQGVHCE 1219
Score = 66.0 bits (158), Expect = 3e-09
Identities = 40/118 (33%), Positives = 51/118 (42%), Gaps = 10/118 (8%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKCVATG----TSYMCK 1392
C +G V + C C + G C + PCL C + G C Y C
Sbjct: 31 CLNGGRCEVANGTEACVCSGAFVGQRCQDPS--PCLSTPCKNAGTCYVVDHGGIVDYACS 88
Query: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHG-QCHISDQGEPYCLCQPGFSGEHCQQENPC 1449
C G+ G LC ANAC A C +G C + E C C PG+SG+ CQQ +PC
Sbjct: 89 CPLGFSGPLC--LTPLANACLANPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPC 144
Score = 64.0 bits (153), Expect = 1e-08
Identities = 48/165 (29%), Positives = 62/165 (37%), Gaps = 21/165 (12%)
Query: 1305 CIHEVRINNELQDFKALPPQSL------GVSPGCKSCTVCKHGLCRSVEKDSVVCECRPG 1358
C+H + +K PQ + C S CK+G CECR G
Sbjct: 1030 CLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAP-CKNGGKCWQTNTQYHCECRSG 1088
Query: 1359 WTGPLCD---------QEARDPCLGHRCHHGK-CVATGTSYMCKCAEGYGGDLCDNKNDS 1408
WTG CD + R + C HG CV + C C GY G C+ D
Sbjct: 1089 WTGFNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEEDKHYCHCQAGYTGSYCE---DE 1145
Query: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPCLGQ 1452
+ CS C +G G C C G+ G +C +E N CL Q
Sbjct: 1146 VDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQ 1190
Score = 63.2 bits (151), Expect = 2e-08
Identities = 37/131 (28%), Positives = 52/131 (39%), Gaps = 10/131 (7%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGY 1397
C+HG + +C C G TGP C+ D C + C G C+ Y C C GY
Sbjct: 612 CRHGGTCQDRDNYYLCLCLKGTTGPNCEINL-DDCASNPCDSGTCLDKIDGYECACEPGY 670
Query: 1398 GGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPCLG 1451
G +C N + + C+ CH+G C C G+ C E NPC+
Sbjct: 671 TGSMC---NVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIH 727
Query: 1452 QVVREVIRRQK 1462
R+ + K
Sbjct: 728 GACRDGLNGYK 738
Score = 62.5 bits (149), Expect = 4e-08
Identities = 43/151 (28%), Positives = 67/151 (43%), Gaps = 19/151 (12%)
Query: 1305 CIHEVRINNELQDFKALPPQSLGVSPGCK------SCTVCKHG-LCRSVEKDSVVCECRP 1357
C H +NE+ ++ ++ P C+ S + C++G CR + C C P
Sbjct: 189 CRHGGTCHNEIGSYRCAC-RATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTHECACLP 247
Query: 1358 GWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLCDNKNDSA----NAC 1412
G+ G C++ D C G+ C +G CV +Y C+C + G C D NAC
Sbjct: 248 GFAGQNCEENV-DDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNAC 306
Query: 1413 SAFKCHHGQCHISDQGEPYCLCQPGFSGEHC 1443
+ G CH + G C+C G++GE C
Sbjct: 307 Q----NAGTCH-NSHGGYNCVCVNGWTGEDC 332
Score = 62.1 bits (148), Expect = 5e-08
Identities = 39/125 (31%), Positives = 60/125 (47%), Gaps = 16/125 (12%)
Query: 1325 SLGVSPGCKSCTVCKH-GLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHH-GKC 1382
+LG +P C+H G C + S C+C G+TGP C+ + + C+ + C + C
Sbjct: 417 ALGANP-------CEHAGKCLNT-LGSFECQCLQGYTGPRCEIDVNE-CISNPCQNDATC 467
Query: 1383 VATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISDQGEPYCLCQPGFSGE 1441
+ + C C GY G C+ D C++ C H+G+C + E C C GFSG
Sbjct: 468 LDQIGEFQCICMPGYEGVYCEINTDE---CASSPCLHNGRC-VDKINEFLCQCPKGFSGH 523
Query: 1442 HCQQE 1446
CQ +
Sbjct: 524 LCQYD 528
Score = 58.9 bits (140), Expect = 4e-07
Identities = 34/112 (30%), Positives = 50/112 (44%), Gaps = 6/112 (5%)
Query: 1337 VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATG-TSYMCKCA 1394
+C+HG E S C CR TGP C+ PC C +G C TG T++ C C
Sbjct: 188 LCRHGGTCHNEIGSYRCACRATHTGPHCELPYV-PCSPSPCQNGGTCRPTGDTTHECACL 246
Query: 1395 EGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE 1446
G+ G C+ D C C +G + C C P ++G++C ++
Sbjct: 247 PGFAGQNCEENVDD---CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTED 295
Score = 58.2 bits (138), Expect = 7e-07
Identities = 42/164 (25%), Positives = 63/164 (37%), Gaps = 50/164 (30%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLC----DQEARDPCL----------GHRC 1377
C+S G C+ + VC CR G++GP C ++ A +PCL G++C
Sbjct: 757 CESNPCVNGGTCKDMTS-GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC 815
Query: 1378 H------------------HGKCVATGT--------SYMCKCAEGYGGDLCDNKNDSANA 1411
+ C +G S+ C C G+ G C+ N
Sbjct: 816 NCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCE---IDINE 872
Query: 1412 CSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPC 1449
C C HG + G CLCQ G++G +C+ + NPC
Sbjct: 873 CVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPC 916
Score = 57.0 bits (135), Expect = 2e-06
Identities = 33/108 (30%), Positives = 45/108 (41%), Gaps = 5/108 (4%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEG 1396
C++G + DS C C G+ G C+ D C C +G CV S+ C C G
Sbjct: 954 CQNGANCTDCVDSYTCTCPTGFNGIHCENNTPD-CTESSCFNGGTCVDGINSFTCLCPPG 1012
Query: 1397 YGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
+ G C N C + C HG G C C G++G +CQ
Sbjct: 1013 FTGSYCQY---DVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQ 1057
Score = 55.4 bits (131), Expect = 5e-06
Identities = 40/165 (24%), Positives = 63/165 (37%), Gaps = 54/165 (32%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPC--LGHRCHH-GKCVATGTS 1388
CK+ C G+ ++ C C P WTG C ++ D C + + C + G C +
Sbjct: 266 CKNGGACVDGV------NTYNCRCPPEWTGQYCTEDV-DECQLMPNACQNAGTCHNSHGG 318
Query: 1389 YMCKCAEGYGGDLCDNKNDSANACSAF--------------KCHHGQ----CHISD---- 1426
Y C C G+ G+ C + D + + F +C HG+ CH++D
Sbjct: 319 YNCVCVNGWTGEDCSDNIDDCASAACFQGATCHDRVASFYCECPHGRTGLLCHLNDACIS 378
Query: 1427 --------------QGEPYCLCQPGFSGEHCQQE--------NPC 1449
G+ C C G++G C Q+ NPC
Sbjct: 379 NPCNEGSNCDTNPVNGKAICTCPRGYTGPACSQDVDECALGANPC 423
Score = 41.4 bits (95), Expect = 0.076
Identities = 27/75 (36%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLG-HRCHH-GKCVATGTS- 1388
C S G C S + S C C +TGP C A PC+G + C++ G C T S
Sbjct: 1352 CGSLRCLNGGTCISGPR-SPTCLCLGSFTGPECQFPASSPCVGSNPCYNQGTCEPTSESP 1410
Query: 1389 -YMCKCAEGYGGDLC 1402
Y C C + G LC
Sbjct: 1411 FYRCLCPAKFNGLLC 1425
>ref|NP_032740.1| Notch gene homolog 1, (Drosophila) [Mus musculus]
sp|Q01705|NTC1_MOUSE NEUROGENIC LOCUS NOTCH HOMOLOG PROTEIN 1 PRECURSOR (MOTCH PROTEIN)
pir||A46019 Notch-1 protein - mouse
emb|CAA77941.1| (Z11886) notch-1 [Mus musculus]
Length = 2531
Score = 198 bits (499), Expect = 3e-49
Identities = 103/301 (34%), Positives = 138/301 (45%), Gaps = 14/301 (4%)
Query: 855 GTNPLHCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDINIV 914
G N CDC+ W E C + D T R GP N
Sbjct: 733 GLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGP---NCQ 789
Query: 915 AKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSD 974
N C S+PC N GTC D V Y+C CP Y G C V + C +PC++ G C S+
Sbjct: 790 TNINECASNPCLNQGTCIDD-VAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESE 848
Query: 975 SHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEV 1034
+ + FSC CP G++GQ A+C + +Y C+C YTG C+
Sbjct: 849 DY-ESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESD 907
Query: 1035 IDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTIN 1094
ID C P N C + C C+C+PG+ G CE D ++C ++ C++GA C D ++
Sbjct: 908 IDDCRP--NPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINECASNPCQNGANCTDCVD 965
Query: 1095 GYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
YTCTCP GF+G CE+ T C + C NG C+ TC CPPGF G C
Sbjct: 966 SYTCTCPVGFNGIHCEN-------NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
Query: 1155 E 1155
+
Sbjct: 1019 Q 1019
Score = 181 bits (454), Expect = 6e-44
Identities = 80/240 (33%), Positives = 119/240 (49%), Gaps = 13/240 (5%)
Query: 920 CLSSPCKNNGTCTQ-DPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKD 978
C +SPCKN+G C + + E + C CP ++G+ C V IN C+++PC+HG +C ++
Sbjct: 833 CATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECVKSPCRHGASCQNTNG--- 889
Query: 979 GFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHC 1038
+ C C G+ G+ +C DGIN C C P + G C+E I+ C
Sbjct: 890 SYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINEC 949
Query: 1039 VPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTC 1098
N CQ+ A C ++C C G++G CE + DC C +G CVD IN +TC
Sbjct: 950 AS--NPCQNGANCTDCVDSYTCTCPVGFNGIHCENNTPDCTESSCFNGGTCVDGINSFTC 1007
Query: 1099 TCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKLI 1158
CP GF+G +C++ + CD C +G C C CP G+ G C+ L+
Sbjct: 1008 LCPPGFTGSYCQY-------DVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQNLV 1060
Score = 173 bits (434), Expect = 1e-41
Identities = 163/664 (24%), Positives = 239/664 (35%), Gaps = 141/664 (21%)
Query: 860 HCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCKGPVDIN--IVAKC 917
+C C W E + A C DR+ F C+ P +
Sbjct: 320 NCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVA------SFYCECPHGRTGLLCHLK 373
Query: 918 NACLSSPCKNNGTCTQDPVELYR-CACPYSYKGKDCTVPINTCI--QNPCQHGGTCHLSD 974
+AC+S+PC C +PV R C CP Y G C+ ++ C N C+H G C
Sbjct: 374 HACISNPCNEGSNCDTNPVNGKRICTCPSGYTGPACSQDVDECDLGANRCEHAGKCL--- 430
Query: 975 SHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEV 1034
+ F C C G+ G ATC+D I + CIC P Y G C+
Sbjct: 431 NTLGSFECQCLQGYTGPGCEIDVNECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEIN 490
Query: 1035 IDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTIN 1094
D C + C H C+ F C+C G++G LC+ D D+C + C++GA+C+D N
Sbjct: 491 TDECAS--SPCLHNGHCMDKIHEFQCQCPKGFNGHLCQYDVDECASTPCKNGAKCLDGPN 548
Query: 1095 GYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
YTC C +G++G CE + CD C G+ C G A C
Sbjct: 549 TYTCVCTEGYTGTHCE-------VDIDECDPDPCHYGS------------CKDGVATFTC 589
Query: 1155 EKLITVNFVGKDSYVELASAKVRPQANISLQVATDKDNGILLY--KGDNDPLALELYQGH 1212
L + G + +P + D+DN L KG P +
Sbjct: 590 --LCQPGYTGHHCETNINECHSQPCRHGG--TCQDRDNSYLCLCLKGTTGP--------N 637
Query: 1213 VRLVYDSLSSPPTTVYSVETVNDGQFHSXXXXXXXXXXXXXXDKGTPKSLGKLQKQPAVG 1272
+ D +S P + DG + G S+ + G
Sbjct: 638 CEINLDDCASNPCDSGTCLDKIDGY-------------ECACEPGYTGSMCNVNIDECAG 684
Query: 1273 INSPLYLGGIPTSTGLSALRQGTDRPLGGFHG--CIHEVR-------INNELQDFKALPP 1323
SP + GG G++ T R G+H C+ EV I+ +D L
Sbjct: 685 --SPCHNGGT-CEDGIAGF---TCRCPEGYHDPTCLSEVNECNSNPCIHGACRD--GLNG 736
Query: 1324 QSLGVSPG------------CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLC----DQE 1367
+PG C+S G C+ + VC CR G++GP C ++
Sbjct: 737 YKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTS-GYVCTCREGFSGPNCQTNINEC 795
Query: 1368 ARDPCL----------GHRCH------------------HGKCVATGT--------SYMC 1391
A +PCL G++C+ C +G S+ C
Sbjct: 796 ASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSC 855
Query: 1392 KCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE----- 1446
C G+ G C+ N C C HG + G CLCQ G++G +C+ +
Sbjct: 856 VCPTGWQGQTCE---VDINECVKSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCR 912
Query: 1447 -NPC 1449
NPC
Sbjct: 913 PNPC 916
Score = 168 bits (422), Expect = 3e-40
Identities = 86/253 (33%), Positives = 118/253 (45%), Gaps = 25/253 (9%)
Query: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
N C S PC + GTC QD Y+C CP Y G +C + C PC++GG C +++
Sbjct: 1023 NECDSRPCLHGGTC-QDSYGTYKCTCPQGYTGLNCQNLVRWCDSAPCKNGGRCWQTNTQ- 1080
Query: 978 DGFSCSCPLGFEG----------QRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYT 1027
+ C C G+ G + CVD + + C C YT
Sbjct: 1081 --YHCECRSGWTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYT 1138
Query: 1028 GELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGA 1087
G C++ +D C P N CQ+ A C GFSC+CV GY G C + ++C++ C++G
Sbjct: 1139 GSYCEDEVDECSP--NPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQPCQNGG 1196
Query: 1088 QCVDTINGYTCTCPQGFSGPFCE-----HPPPMVLLQTSPCDQYECQNGAQCIVVQQEPT 1142
C+D N Y C+CP+G G CE PP+ SP +C N C+ T
Sbjct: 1197 TCIDLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSP----KCFNNGTCVDQVGGYT 1252
Query: 1143 CRCPPGFAGPRCE 1155
C CPPGF G RCE
Sbjct: 1253 CTCPPGFVGERCE 1265
Score = 165 bits (413), Expect = 4e-39
Identities = 92/276 (33%), Positives = 124/276 (44%), Gaps = 20/276 (7%)
Query: 880 GIARCSSPEPMADRLLLTTPTHRFQC-KGPVDINIVAKCNACLSSPCKNNGTCTQDPVEL 938
G RC A + L T + QC +G N C+S+PC+N+ TC D +
Sbjct: 419 GANRCEH----AGKCLNTLGSFECQCLQGYTGPGCEIDVNECISNPCQNDATCL-DQIGE 473
Query: 939 YRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXX 998
++C C Y+G C + + C +PC H G C + H+ F C CP GF G
Sbjct: 474 FQCICMPGYEGVYCEINTDECASSPCLHNGHC-MDKIHE--FQCQCPKGFNGHLCQYDVD 530
Query: 999 XXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGF 1058
A C+DG N Y C+C YTG C+ ID C P+ C H C F
Sbjct: 531 ECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD--PC-HYGSCKDGVATF 587
Query: 1059 SCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLL 1118
+C C PGY+G CET+ ++C + CRHG C D N Y C C +G +GP CE +
Sbjct: 588 TCLCQPGYTGHHCETNINECHSQPCRHGGTCQDRDNSYLCLCLKGTTGPNCE-------I 640
Query: 1119 QTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRC 1154
C C +G C+ C C PG+ G C
Sbjct: 641 NLDDCASNPCDSGT-CLDKIDGYECACEPGYTGSMC 675
Score = 159 bits (398), Expect = 2e-37
Identities = 92/294 (31%), Positives = 123/294 (41%), Gaps = 53/294 (18%)
Query: 903 FQCKGPV---DINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTC 959
F C+ P D +++ N C S+PC + G C +D + Y+C C + G +C + N C
Sbjct: 700 FTCRCPEGYHDPTCLSEVNECNSNPCIH-GAC-RDGLNGYKCDCAPGWSGTNCDINNNEC 757
Query: 960 IQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYV 1019
NPC +GGTC S G+ C+C GF G TC+D + Y
Sbjct: 758 ESNPCVNGGTCKDMTS---GYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYK 814
Query: 1020 CICPPNYTGELCDEVIDHCVP-------------------------------ELNL---- 1044
C CP YTG C+ V+ C E+++
Sbjct: 815 CNCPLPYTGATCEVVLAPCATSPCKNSGVCKESEDYESFSCVCPTGWQGQTCEVDINECV 874
Query: 1045 ---CQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYTCTCP 1101
C+H A C + + C C GY+G+ CE+D DDC + C +G C D IN C C
Sbjct: 875 KSPCRHGASCQNTNGSYRCLCQAGYTGRNCESDIDDCRPNPCHNGGSCTDGINTAFCDCL 934
Query: 1102 QGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
GF G FCE + C CQNGA C TC CP GF G CE
Sbjct: 935 PGFQGAFCEE-------DINECASNPCQNGANCTDCVDSYTCTCPVGFNGIHCE 981
Score = 159 bits (398), Expect = 2e-37
Identities = 80/243 (32%), Positives = 110/243 (44%), Gaps = 15/243 (6%)
Query: 918 NACLSSP--CKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDS 975
N C +P C++ G C + + YRCAC ++ G C +P C +PCQ+G TC +
Sbjct: 180 NECSQNPGLCRHGGHCHNE-IGSYRCACCATHTGPHCELPYVPCSPSPCQNGATCRPTGD 238
Query: 976 HKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVI 1035
C+C GF GQ CVDG+N Y C CPP TG+ C E +
Sbjct: 239 TTH--ECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEVTGQYCTEDV 296
Query: 1036 DHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTING 1095
D C N CQ+ C G++C CV G++G+ C + DDC + C GA C D +
Sbjct: 297 DECQLMPNACQNAGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVAS 356
Query: 1096 YTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIV--VQQEPTCRCPPGFAGPR 1153
+ C CP G +G C C C G+ C V + C CP G+ GP
Sbjct: 357 FYCECPHGRTGLLCH--------LKHACISNPCNEGSNCDTNPVNGKRICTCPSGYTGPA 408
Query: 1154 CEK 1156
C +
Sbjct: 409 CSQ 411
Score = 157 bits (392), Expect = 1e-36
Identities = 86/261 (32%), Positives = 116/261 (43%), Gaps = 25/261 (9%)
Query: 901 HRFQCKGPVDIN---IVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPIN 957
H FQC+ P N + C S+PCKN C P Y C C Y G C V I+
Sbjct: 510 HEFQCQCPKGFNGHLCQYDVDECASTPCKNGAKCLDGP-NTYTCVCTEGYTGTHCEVDID 568
Query: 958 TCIQNPCQHGGTCHLSDSHKDG---FSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDG 1014
C +PC H G+C KDG F+C C G+ G TC D
Sbjct: 569 ECDPDPC-HYGSC------KDGVATFTCLCQPGYTGHHCETNINECHSQPCRHGGTCQDR 621
Query: 1015 INNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETD 1074
N+Y+C+C TG C+ +D C N C C+ G+ C C PGY+G +C +
Sbjct: 622 DNSYLCLCLKGTTGPNCEINLDDCAS--NPCD-SGTCLDKIDGYECACEPGYTGSMCNVN 678
Query: 1075 NDDCVAHKCRHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQC 1134
D+C C +G C D I G+TC CP+G+ P C L + + C+ C +GA C
Sbjct: 679 IDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTC-------LSEVNECNSNPCIHGA-C 730
Query: 1135 IVVQQEPTCRCPPGFAGPRCE 1155
C C PG++G C+
Sbjct: 731 RDGLNGYKCDCAPGWSGTNCD 751
Score = 156 bits (391), Expect = 1e-36
Identities = 85/298 (28%), Positives = 125/298 (41%), Gaps = 53/298 (17%)
Query: 900 THRFQC-KGPVDINIVAKCNACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINT 958
TH C G N + C + CKN G C D V Y C CP G+ CT ++
Sbjct: 240 THECACLPGFAGQNCEENVDDCPGNNCKNGGACV-DGVNTYNCRCPPEVTGQYCTEDVDE 298
Query: 959 C--IQNPCQHGGTCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGIN 1016
C + N CQ+ GTCH ++H G++C C G+ G+ ATC D +
Sbjct: 299 CQLMPNACQNAGTCH--NTH-GGYNCVCVNGWTGEDCSENIDDCASAACFQGATCHDRVA 355
Query: 1017 NY---------------------------------------VCICPPNYTGELCDEVIDH 1037
++ +C CP YTG C + +D
Sbjct: 356 SFYCECPHGRTGLLCHLKHACISNPCNEGSNCDTNPVNGKRICTCPSGYTGPACSQDVDE 415
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C N C+H KC+ F C+C+ GY+G CE D ++C+++ C++ A C+D I +
Sbjct: 416 CDLGANRCEHAGKCLNTLGSFECQCLQGYTGPGCEIDVNECISNPCQNDATCLDQIGEFQ 475
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
C C G+ G +CE + T C C + C+ E C+CP GF G C+
Sbjct: 476 CICMPGYEGVYCE-------INTDECASSPCLHNGHCMDKIHEFQCQCPKGFNGHLCQ 526
Score = 154 bits (385), Expect = 7e-36
Identities = 80/241 (33%), Positives = 109/241 (45%), Gaps = 15/241 (6%)
Query: 918 NACLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHK 977
N C S PC++ GTC QD Y C C G +C + ++ C NPC GTC
Sbjct: 605 NECHSQPCRHGGTC-QDRDNSYLCLCLKGTTGPNCEINLDDCASNPCD-SGTCL---DKI 659
Query: 978 DGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDH 1037
DG+ C+C G+ G TC DGI + C CP Y C ++
Sbjct: 660 DGYECACEPGYTGSMCNVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNE 719
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C N C H A C G+ C+C PG+SG C+ +N++C ++ C +G C D +GY
Sbjct: 720 C--NSNPCIHGA-CRDGLNGYKCDCAPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYV 776
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEKL 1157
CTC +GFSGP C+ + C C N CI C CP + G CE +
Sbjct: 777 CTCREGFSGPNCQ-------TNINECASNPCLNQGTCIDDVAGYKCNCPLPYTGATCEVV 829
Query: 1158 I 1158
+
Sbjct: 830 L 830
Score = 149 bits (373), Expect = 2e-34
Identities = 73/238 (30%), Positives = 109/238 (45%), Gaps = 14/238 (5%)
Query: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
C S+ C TC D V + C CP+ G C + + CI NPC G C + +
Sbjct: 339 CASAACFQGATC-HDRVASFYCECPHGRTGLLCHLK-HACISNPCNEGSNCDTNPVNGKR 396
Query: 980 FSCSCPLGFEGQRXXXXXXXXXXXXXX--XXATCVDGINNYVCICPPNYTGELCDEVIDH 1037
C+CP G+ G C++ + ++ C C YTG C+ ++
Sbjct: 397 I-CTCPSGYTGPACSQDVDECDLGANRCEHAGKCLNTLGSFECQCLQGYTGPGCEIDVNE 455
Query: 1038 CVPELNLCQHEAKCIPLDKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGYT 1097
C+ N CQ++A C+ F C C+PGY G CE + D+C + C H C+D I+ +
Sbjct: 456 CIS--NPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCLHNGHCMDKIHEFQ 513
Query: 1098 CTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCE 1155
C CP+GF+G C++ C C+NGA+C+ TC C G+ G CE
Sbjct: 514 CQCPKGFNGHLCQY-------DVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCE 564
Score = 142 bits (355), Expect = 2e-32
Identities = 78/242 (32%), Positives = 108/242 (44%), Gaps = 14/242 (5%)
Query: 920 CLSSPCKNNGTCTQDPVELYRCACPYSYKGKDCTVPINTCIQNPCQHGGTCHLSDSHKDG 979
CL++PC+N GTC + Y+C C + GK C + C NPC +GG C +S
Sbjct: 106 CLANPCRNGGTCDLLTLTEYKCRCSPGWSGKSCQ-QADPCASNPCANGGQCLPFES---S 161
Query: 980 FSCSCPLGFEGQ--RXXXXXXXXXXXXXXXXATCVDGINNYVCICPPNYTGELCDEVIDH 1037
+ C CP GF G R C + I +Y C C +TG C+
Sbjct: 162 YICRCPPGFHGPTCRQDVNECSQNPGLCRHGGHCHNEIGSYRCACCATHTGPHCELPYVP 221
Query: 1038 CVPELNLCQHEAKCIPL-DKGFSCECVPGYSGKLCETDNDDCVAHKCRHGAQCVDTINGY 1096
C P + CQ+ A C P D C C+PG++G+ CE + DDC + C++G CVD +N Y
Sbjct: 222 CSP--SPCQNGATCRPTGDTTHECACLPGFAGQNCEENVDDCPGNNCKNGGACVDGVNTY 279
Query: 1097 TCTCPQGFSGPFCEHPPPMVLLQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEK 1156
C CP +G +C L + C QN C C C G+ G C +
Sbjct: 280 NCRCPPEVTGQYCTEDVDECQLMPNAC-----QNAGTCHNTHGGYNCVCVNGWTGEDCSE 334
Query: 1157 LI 1158
I
Sbjct: 335 NI 336
Score = 141 bits (352), Expect = 6e-32
Identities = 96/324 (29%), Positives = 136/324 (41%), Gaps = 38/324 (11%)
Query: 860 HCDCSLRWLSEWVKAGYKEPGIARCSSPEPMADRLLLTTPTHRFQCK---GPVDINIVAK 916
+C C + Y E + CS P P + T F CK G N +
Sbjct: 1130 YCHCQAGYTGS-----YCEDEVDECS-PNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEE 1183
Query: 917 CNACLSSPCKNNGTCTQDPVELYRCACPYSYKG-------KDCTVPINTCIQNP-CQHGG 968
N CLS PC+N GTC D Y+C+CP +G DC P++ ++P C + G
Sbjct: 1184 INECLSQPCQNGGTCI-DLTNSYKCSCPRGTQGVHCEINVDDCHPPLDPASRSPKCFNNG 1242
Query: 969 TCHLSDSHKDGFSCSCPLGFEGQRXXXXXXXXXXXXXXXXAT--CVDGINNYVCICPPNY 1026
TC G++C+CP GF G+R T CV +N++ C C +
Sbjct: 1243 TCV---DQVGGYTCTCPPGFVGERCEGDVNECLSNPCDPRGTQNCVQRVNDFHCECRAGH 1299
Query: 1027 TGELCDEVIDHCVPELNLCQHEAKCIPLD---KGFSCECVPGYSGKLCETDNDDCVAHKC 1083
TG C+ VI+ C + C++ C +GF C C G+ G CE D C + +C
Sbjct: 1300 TGRRCESVINGCRGKP--CKNGGVCAVASNTARGFICRCPAGFEGATCENDARTCGSLRC 1357
Query: 1084 RHGAQCVDTINGYTCTCPQGFSGPFCEHPPPMVLLQTSPC-DQYECQNGAQCIVVQQEP- 1141
+G C+ TC C F+GP C+ P +SPC C N C + P
Sbjct: 1358 LNGGTCISGPRSPTCLCLGSFTGPECQFP------ASSPCVGSNPCYNQGTCEPTSENPF 1411
Query: 1142 -TCRCPPGFAGPRCEKLITVNFVG 1164
C CP F G C ++ +F G
Sbjct: 1412 YRCLCPAKFNGLLCH-ILDYSFTG 1434
Score = 96.7 bits (237), Expect = 2e-18
Identities = 52/159 (32%), Positives = 77/159 (47%), Gaps = 23/159 (14%)
Query: 1010 TCVDG------INNYVCICPPNYTGELCDEVIDHCVPELNLCQHEAKCIPLDKG----FS 1059
TC++G C+ ++ G+ C + + C+ C++ C +D G ++
Sbjct: 30 TCLNGGRCEVASGTEACVASGSFVGQRCQDP-NPCLS--TRCKNAGTCYVVDHGGIVDYA 86
Query: 1060 CECVPGYSGKLCETDNDD-CVAHKCRHGAQC-VDTINGYTCTCPQGFSGPFCEHPPPMVL 1117
C C G+SG LC T D C+A+ CR+G C + T+ Y C C G+SG C+
Sbjct: 87 CSCPLGFSGPLCLTPLDKPCLANPCRNGGTCDLLTLTEYKCRCSPGWSGKSCQ------- 139
Query: 1118 LQTSPCDQYECQNGAQCIVVQQEPTCRCPPGFAGPRCEK 1156
Q PC C NG QC+ + CRCPPGF GP C +
Sbjct: 140 -QADPCASNPCANGGQCLPFESSYICRCPPGFHGPTCRQ 177
Score = 76.5 bits (185), Expect = 2e-12
Identities = 42/125 (33%), Positives = 56/125 (44%), Gaps = 15/125 (12%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYM 1390
CK+ VCK S + +S C C GW G C+ + + C+ C HG C T SY
Sbjct: 838 CKNSGVCKE----SEDYESFSCVCPTGWQGQTCEVDINE-CVKSPCRHGASCQNTNGSYR 892
Query: 1391 CKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE---- 1446
C C GY G C++ D C CH+G +C C PGF G C+++
Sbjct: 893 CLCQAGYTGRNCESDIDD---CRPNPCHNGGSCTDGINTAFCDCLPGFQGAFCEEDINEC 949
Query: 1447 --NPC 1449
NPC
Sbjct: 950 ASNPC 954
Score = 76.1 bits (184), Expect = 3e-12
Identities = 38/107 (35%), Positives = 56/107 (51%), Gaps = 11/107 (10%)
Query: 1352 VCECRPGWTGPLCDQEARDPCLG-HRCHH-GKCVATGTSYMCKCAEGYGGDLCDNKNDSA 1409
+C C G+TGP C Q+ + LG +RC H GKC+ T S+ C+C +GY G C+
Sbjct: 397 ICTCPSGYTGPACSQDVDECDLGANRCEHAGKCLNTLGSFECQCLQGYTGPGCE---IDV 453
Query: 1410 NACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ------QENPCL 1450
N C + C + + GE C+C PG+ G +C+ +PCL
Sbjct: 454 NECISNPCQNDATCLDQIGEFQCICMPGYEGVYCEINTDECASSPCL 500
Score = 71.8 bits (173), Expect = 5e-11
Identities = 41/121 (33%), Positives = 60/121 (48%), Gaps = 11/121 (9%)
Query: 1336 TVCKH-GLCRSVEKDSVV---CECRPGWTGPLCDQEARDPCLGHRCHHGKC--VATGTSY 1389
T CK+ G C V+ +V C C G++GPLC PCL + C +G + T T Y
Sbjct: 66 TRCKNAGTCYVVDHGGIVDYACSCPLGFSGPLCLTPLDKPCLANPCRNGGTCDLLTLTEY 125
Query: 1390 MCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NP 1448
C+C+ G+ G C A+ C++ C +G + + C C PGF G C+Q+ N
Sbjct: 126 KCRCSPGWSGKSCQQ----ADPCASNPCANGGQCLPFESSYICRCPPGFHGPTCRQDVNE 181
Query: 1449 C 1449
C
Sbjct: 182 C 182
Score = 69.9 bits (168), Expect = 2e-10
Identities = 37/105 (35%), Positives = 50/105 (47%), Gaps = 10/105 (9%)
Query: 1353 CECRPGWTGPLCDQEARDPCLGHRCHHGKCVA----TGTSYMCKCAEGYGGDLCDNKNDS 1408
CECR G TG C+ C G C +G A T ++C+C G+ G C+N
Sbjct: 1293 CECRAGHTGRRCESVING-CRGKPCKNGGVCAVASNTARGFICRCPAGFEGATCEN---D 1348
Query: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ--QENPCLG 1451
A C + +C +G IS P CLC F+G CQ +PC+G
Sbjct: 1349 ARTCGSLRCLNGGTCISGPRSPTCLCLGSFTGPECQFPASSPCVG 1393
Score = 69.9 bits (168), Expect = 2e-10
Identities = 38/123 (30%), Positives = 58/123 (46%), Gaps = 7/123 (5%)
Query: 1326 LGVSPGCKSCTV--CKHG-LCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-K 1381
L ++P K C C++G C + C C PGW+G C Q DPC + C +G +
Sbjct: 97 LCLTPLDKPCLANPCRNGGTCDLLTLTEYKCRCSPGWSGKSCQQA--DPCASNPCANGGQ 154
Query: 1382 CVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGE 1441
C+ +SY+C+C G+ G C + + H G CH ++ G C C +G
Sbjct: 155 CLPFESSYICRCPPGFHGPTCRQDVNECSQNPGLCRHGGHCH-NEIGSYRCACCATHTGP 213
Query: 1442 HCQ 1444
HC+
Sbjct: 214 HCE 216
Score = 68.7 bits (165), Expect = 5e-10
Identities = 33/109 (30%), Positives = 51/109 (46%), Gaps = 11/109 (10%)
Query: 1349 DSVVCECRPGWTGPLCDQEARDPCLGHRCHHG-KCVATGTSYMCKCAEGYGGDLCDNKND 1407
++ C+C PG+ G C+++ + C + C +G C SY C C G+ G C+N
Sbjct: 927 NTAFCDCLPGFQGAFCEEDINE-CASNPCQNGANCTDCVDSYTCTCPVGFNGIHCENNTP 985
Query: 1408 SANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPCL 1450
C+ C +G + CLC PGF+G +CQ + PCL
Sbjct: 986 D---CTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQYDVNECDSRPCL 1031
Score = 67.9 bits (163), Expect = 8e-10
Identities = 49/165 (29%), Positives = 63/165 (37%), Gaps = 21/165 (12%)
Query: 1305 CIHEVRINNELQDFKALPPQSL------GVSPGCKSCTVCKHGLCRSVEKDSVVCECRPG 1358
C+H + +K PQ + C S CK+G CECR G
Sbjct: 1030 CLHGGTCQDSYGTYKCTCPQGYTGLNCQNLVRWCDSAP-CKNGGRCWQTNTQYHCECRSG 1088
Query: 1359 WTGPLCD---------QEARDPCLGHRCHHGK-CVATGTSYMCKCAEGYGGDLCDNKNDS 1408
WTG CD + R + C HG CV G + C C GY G C+ D
Sbjct: 1089 WTGVNCDVLSVSCEVAAQKRGIDVTLLCQHGGLCVDEGDKHYCHCQAGYTGSYCE---DE 1145
Query: 1409 ANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE-NPCLGQ 1452
+ CS C +G G C C G+ G +C +E N CL Q
Sbjct: 1146 VDECSPNPCQNGATCTDYLGGFSCKCVAGYHGSNCSEEINECLSQ 1190
Score = 67.9 bits (163), Expect = 8e-10
Identities = 42/128 (32%), Positives = 53/128 (40%), Gaps = 18/128 (14%)
Query: 1332 CKSCTVCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMC 1391
C + C+ G+ C C G+ P C E + C + C HG C Y C
Sbjct: 687 CHNGGTCEDGIA------GFTCRCPEGYHDPTCLSEVNE-CNSNPCIHGACRDGLNGYKC 739
Query: 1392 KCAEGYGGDLCDNKNDSANACSAFKC-HHGQCHISDQGEPYCLCQPGFSGEHCQ------ 1444
CA G+ G CD N N C + C + G C G C C+ GFSG +CQ
Sbjct: 740 DCAPGWSGTNCDINN---NECESNPCVNGGTCKDMTSGY-VCTCREGFSGPNCQTNINEC 795
Query: 1445 QENPCLGQ 1452
NPCL Q
Sbjct: 796 ASNPCLNQ 803
Score = 67.5 bits (162), Expect = 1e-09
Identities = 42/157 (26%), Positives = 64/157 (40%), Gaps = 17/157 (10%)
Query: 1305 CIHEVRINNELQDFKALPPQSLGVS------PGCKSCTVCKHGLCRSVEKDSVVCECRPG 1358
C+H +++ +F+ P+ C S T CK+G ++ C C G
Sbjct: 499 CLHNGHCMDKIHEFQCQCPKGFNGHLCQYDVDECAS-TPCKNGAKCLDGPNTYTCVCTEG 557
Query: 1359 WTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGYGGDLCDNKNDSANACSAFKCH 1418
+TG C+ + D C CH+G C ++ C C GY G C+ + N C + C
Sbjct: 558 YTGTHCEVDI-DECDPDPCHYGSCKDGVATFTCLCQPGYTGHHCET---NINECHSQPCR 613
Query: 1419 HGQCHISDQGEPYCLCQPGFSGEHCQ------QENPC 1449
HG CLC G +G +C+ NPC
Sbjct: 614 HGGTCQDRDNSYLCLCLKGTTGPNCEINLDDCASNPC 650
Score = 66.0 bits (158), Expect = 3e-09
Identities = 38/112 (33%), Positives = 51/112 (44%), Gaps = 11/112 (9%)
Query: 1337 VCKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYM----CK 1392
+C+HG E D C C+ G+TG C+ E D C + C +G AT T Y+ CK
Sbjct: 1115 LCQHGGLCVDEGDKHYCHCQAGYTGSYCEDEV-DECSPNPCQNG---ATCTDYLGGFSCK 1170
Query: 1393 CAEGYGGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQ 1444
C GY G C ++ N C + C +G I C C G G HC+
Sbjct: 1171 CVAGYHGSNC---SEEINECLSQPCQNGGTCIDLTNSYKCSCPRGTQGVHCE 1219
Score = 65.6 bits (157), Expect = 4e-09
Identities = 38/131 (29%), Positives = 53/131 (40%), Gaps = 10/131 (7%)
Query: 1338 CKHGLCRSVEKDSVVCECRPGWTGPLCDQEARDPCLGHRCHHGKCVATGTSYMCKCAEGY 1397
C+HG +S +C C G TGP C+ D C + C G C+ Y C C GY
Sbjct: 612 CRHGGTCQDRDNSYLCLCLKGTTGPNCEINL-DDCASNPCDSGTCLDKIDGYECACEPGY 670
Query: 1398 GGDLCDNKNDSANACSAFKCHHGQCHISDQGEPYCLCQPGFSGEHCQQE------NPCLG 1451
G +C N + + C+ CH+G C C G+ C E NPC+
Sbjct: 671 TGSMC---NVNIDECAGSPCHNGGTCEDGIAGFTCRCPEGYHDPTCLSEVNECNSNPCIH 727
Query: 1452 QVVREVIRRQK 1462
R+ + K
Sbjct: 728 GACRDGLNGYK 738
Lambda K H
0.321 0.137 0.436
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 564776372
Number of Sequences: 582290
Number of extensions: 24862239
Number of successful extensions: 121482
Number of sequences better than 10.0: 2457
Number of HSP's better than 10.0 without gapping: 1218
Number of HSP's successfully gapped in prelim test: 1250
Number of HSP's that attempted gapping in prelim test: 54554
Number of HSP's gapped (non-prelim): 29407
length of query: 1523
length of database: 183,345,511
effective HSP length: 55
effective length of query: 1468
effective length of database: 151,319,561
effective search space: 222137115548
effective search space used: 222137115548
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 77 (34.4 bits)
