Score E
Sequences producing significant alignments: (bits) Value
ref|NP_055125.1| similar to mouse Ras, dexamethasone-induce... 564 e-160
ref|XP_001019.1| similar to mouse Ras, dexamethasone-induce... 548 e-155
gb|AAD38928.1|AF134409_1 (AF134409) Rhes protein [Rattus no... 516 e-145
gb|AAF72997.1|AF262018_1 (AF262018) dexamethasone-induced r... 348 5e-95
ref|NP_057168.1| ras-related protein [Homo sapiens] >gi|495... 348 5e-95
gb|AAF43090.1|AF239157_1 (AF239157) DEXRAS1 [Rattus norvegi... 347 8e-95
ref|NP_033052.1| RAS, dexamethasone-induced 1 [Mus musculus... 346 1e-94
gb|AAF50620.1| (AE003560) CG8641 gene product [Drosophila m... 231 5e-60
gb|AAG17979.1|AF177335_1 (AF177335) unknown [Homo sapiens] 218 7e-56
emb|CAB43324.1| (AL050231) /prediction=(method:""genefinder... 138 6e-32
gb|AAD13119.1| (AC006538) BC41195_1 [Homo sapiens] 138 9e-32
pir||T15833 hypothetical protein C54A12.4 - Caenorhabditis ... 128 6e-29
gb|AAF54453.1| (AE003684) CG8500 gene product [Drosophila m... 127 1e-28
gb|AAF45493.1| (AE003417) EG:BACR37P7.8 gene product [Droso... 126 2e-28
ref|NP_006261.1| related RAS viral (r-ras) oncogene homolog... 120 1e-26
sp|P18613|RAP1_DICDI RAS-RELATED PROTEIN RAP-1 >gi|102240|p... 120 1e-26
gb|AAB58345.1| (AF000653) Pprap1 protein [Physarum polyceph... 120 2e-26
sp|Q94694|RAP1_PHYPO RAS-RELATED PROTEIN RAP-1 (PPRAP1) >gi... 120 2e-26
pdb|1KAO| Crystal Structure Of The Small G Protein Rap2a ... 119 4e-26
ref|NP_066361.1| RAP2A, member of RAS oncogene family; RAP2... 119 4e-26
ref|NP_002877.1| RAP2B, member of RAS oncogene family [Homo... 118 7e-26
sp|P22126|RAS1_NEUCR RAS-1 PROTEIN >gi|101876|pir||S12892 t... 118 7e-26
sp|O42785|RASL_COLTR RAS-LIKE PROTEIN >gi|2906025|gb|AAC037... 117 2e-25
sp|P38976|RAS2_HYDMA RAS-LIKE PROTEIN RAS2 >gi|323160|pir||... 117 2e-25
ref|NP_067006.1| hypothetical protein similar to small G pr... 116 2e-25
sp|P87018|RAS_BOTCI RAS-LIKE PROTEIN >gi|1916796|gb|AAB5123... 116 2e-25
sp|P34729|RAS1_PHYPO RAS-LIKE PROTEIN 1 >gi|422302|pir||S33... 116 2e-25
sp|P34726|RAS2_PHYPO RAS-LIKE PROTEIN 2 >gi|542202|pir||S38... 116 3e-25
sp|P03967|RASD_DICDI RAS-LIKE PROTEIN RASD (TRANSFORMING PR... 116 3e-25
pir||A61216 transforming protein rap1b - rat (strain Copenh... 115 5e-25
ref|NP_033127.1| Harvey rat sarcoma oncogene, subgroup R [M... 115 5e-25
ref|NP_056461.1| RAP1B, member of RAS oncogene family; RAS-... 115 5e-25
gb|AAF17287.1|U45968_1 (U45968) G-protein [Oncorhynchus myk... 115 6e-25
gb|AAF17286.1|U45967_1 (U45967) G-protein [Oncorhynchus myk... 115 6e-25
pdb|1GUA|A Chain A, Human Rap1a, Residues 1-167, Double Mut... 115 6e-25
sp|P22279|RAS2_RHIRA RAS-LIKE PROTEIN 2 >gi|553070|gb|AAA83... 115 8e-25
sp|P08645|RAS3_DROME RAS-LIKE PROTEIN 3 (ROUGHENED PROTEIN)... 115 8e-25
gb|AAD10840.1| (U53783) Rap1b [Cyprinus carpio] 114 1e-24
pir||JC5155 rap1A protein - turkey >gi|1694835|emb|CAA59757... 114 1e-24
gb|AAF03566.1|AF134251_1 (AF134251) Ras homolog type A [Can... 114 1e-24
gb|AAD52662.1|AF177670_1 (AF177670) Ras1p [Candida albicans... 114 1e-24
sp|P22123|RAPA_DISOM RAS-RELATED PROTEIN O-KREV >gi|213107|... 114 1e-24
pir||F38625 GTP-binding protein o-Krev - electric ray (Disc... 114 1e-24
sp|P08647|RAS_SCHPO RAS-LIKE PROTEIN 1 >gi|7493264|pir||T37... 113 2e-24
pir||TVBYPR transforming protein ras - fission yeast (Schiz... 113 2e-24
pdb|1C1Y|A Chain A, Crystal Structure Of Rap.Gmppnp In Comp... 113 2e-24
ref|NP_002875.1| RAP1A, member of RAS oncogene family; RAS-... 113 2e-24
gb|AAB09439.1| (U53177) Psmras1 [Schistosoma mansoni] 113 3e-24
emb|CAA26191.1| (X02331) SPRAS-protein [Schizosaccharomyces... 113 3e-24
ref|NP_062666.1| GTP-binding protein ROC2 [Mus musculus] >g... 112 4e-24
>ref|NP_055125.1| similar to mouse Ras, dexamethasone-induced 1; tumor endothelial
marker 2 [Homo sapiens]
ref|XP_001020.1| similar to mouse Ras, dexamethasone-induced 1 [Homo sapiens]
emb|CAA18456.1| (AL022334) dJ569D19.1 (similar to mouse Ras, Dexamethasone-induced
1 (Ras-related protein, RASD1, DEXRAS1)) [Homo sapiens]
gb|AAG00868.1|AF279143_1 (AF279143) tumor endothelial marker 2 [Homo sapiens]
Length = 278
Score = 564 bits (1439), Expect = e-160
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MPASLALLQPRAMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQY 60
MPASLALLQPRAMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQY
Sbjct: 1 MPASLALLQPRAMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQY 60
Query: 61 TPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDE 120
TPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDE
Sbjct: 61 TPTIEDFHRKVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDE 120
Query: 121 VKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAY 180
VKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAY
Sbjct: 121 VKRLQKQILEVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAY 180
Query: 181 FEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAY 240
FEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAY
Sbjct: 181 FEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAY 240
Query: 241 GMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTIQ 278
GMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTIQ
Sbjct: 241 GMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTIQ 278
>ref|XP_001019.1| similar to mouse Ras, dexamethasone-induced 1 [Homo sapiens]
Length = 316
Score = 548 bits (1398), Expect = e-155
Identities = 269/269 (100%), Positives = 269/269 (100%)
Query: 10 PRAMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHR 69
PRAMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHR
Sbjct: 48 PRAMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHR 107
Query: 70 KVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQIL 129
KVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQIL
Sbjct: 108 KVYNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQIL 167
Query: 130 EVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNT 189
EVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNT
Sbjct: 168 EVKSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNT 227
Query: 190 NVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARR 249
NVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARR
Sbjct: 228 NVDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARR 287
Query: 250 PSVNSDLKYIKAKVLREGQARERDKCTIQ 278
PSVNSDLKYIKAKVLREGQARERDKCTIQ
Sbjct: 288 PSVNSDLKYIKAKVLREGQARERDKCTIQ 316
>gb|AAD38928.1|AF134409_1 (AF134409) Rhes protein [Rattus norvegicus]
Length = 266
Score = 516 bits (1314), Expect = e-145
Identities = 253/266 (95%), Positives = 257/266 (96%)
Query: 13 MMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY 72
MMKTLSSGNCTL+VPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY
Sbjct: 1 MMKTLSSGNCTLNVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVY 60
Query: 73 NIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVK 132
NI GDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLD+RESFDEVKRLQKQILEVK
Sbjct: 61 NIHGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDSRESFDEVKRLQKQILEVK 120
Query: 133 SCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVD 192
SCLKNKTKEAAELPMVICGNKNDH ELCRQVP EAELLVSGDENCAYFEVSAKKNTNV+
Sbjct: 121 SCLKNKTKEAAELPMVICGNKNDHSELCRQVPAMEAELLVSGDENCAYFEVSAKKNTNVN 180
Query: 193 EMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEMDAYGMVSPFARRPSV 252
EMFYVLFSMAKLPHEMSPALH KISVQYGDAFHPRPFCMRR K AYGMVSPFARRPSV
Sbjct: 181 EMFYVLFSMAKLPHEMSPALHHKISVQYGDAFHPRPFCMRRTKVAGAYGMVSPFARRPSV 240
Query: 253 NSDLKYIKAKVLREGQARERDKCTIQ 278
NSDLKYIKAKVLREGQARERDKC+IQ
Sbjct: 241 NSDLKYIKAKVLREGQARERDKCSIQ 266
>gb|AAF72997.1|AF262018_1 (AF262018) dexamethasone-induced ras-related protein 1 [Homo
sapiens]
Length = 281
Score = 348 bits (883), Expect = 5e-95
Identities = 172/277 (62%), Positives = 217/277 (78%), Gaps = 12/277 (4%)
Query: 12 AMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKV 71
AM+K + + LS+PAKN YRMV+LG+S+VGK++IVSRFL GRFED YTPTIEDFHRK
Sbjct: 5 AMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKF 64
Query: 72 YNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEV 131
Y+IRG++YQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNR+SF+EV+RL++QIL+
Sbjct: 65 YSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDT 124
Query: 132 KSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGD-ENCAYFEVSAKKNTN 190
KSCLKNKTKE ++P+VICGNK D + R+V E E LV D + CAYFE+SAKKN++
Sbjct: 125 KSCLKNKTKENVDVPLVICGNKGDR-DFYREVDQREIEQLVGDDPQRCAYFEISAKKNSS 183
Query: 191 VDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEM----------DAY 240
+D+MF LF+MAKLP EMSP LHRK+SVQY D H + +++ DA+
Sbjct: 184 LDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAF 243
Query: 241 GMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTI 277
G+V+PFARRPSV+SDL YI+ K QA+++++C I
Sbjct: 244 GIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVI 280
>ref|NP_057168.1| ras-related protein [Homo sapiens]
gb|AAD34206.1|AF069506_1 (AF069506) activator of G protein signaling [Homo sapiens]
gb|AAD34621.1| (AF153192) ras-related protein [Homo sapiens]
gb|AAF01364.1|AF172846_1 (AF172846) ras-related protein [Homo sapiens]
Length = 281
Score = 348 bits (883), Expect = 5e-95
Identities = 172/277 (62%), Positives = 217/277 (78%), Gaps = 12/277 (4%)
Query: 12 AMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKV 71
AM+K + + LS+PAKN YRMV+LG+S+VGK++IVSRFL GRFED YTPTIEDFHRK
Sbjct: 5 AMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKF 64
Query: 72 YNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEV 131
Y+IRG++YQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNR+SF+EV+RL++QIL+
Sbjct: 65 YSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDT 124
Query: 132 KSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGD-ENCAYFEVSAKKNTN 190
KSCLKNKTKE ++P+VICGNK D + R+V E E LV D + CAYFE+SAKKN++
Sbjct: 125 KSCLKNKTKENVDVPLVICGNKGDR-DFYREVDQREIEQLVGDDPQRCAYFEISAKKNSS 183
Query: 191 VDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEM----------DAY 240
+D+MF LF+MAKLP EMSP LHRK+SVQY D H + +++ DA+
Sbjct: 184 LDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAF 243
Query: 241 GMVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTI 277
G+V+PFARRPSV+SDL YI+ K QA+++++C I
Sbjct: 244 GIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVI 280
>gb|AAF43090.1|AF239157_1 (AF239157) DEXRAS1 [Rattus norvegicus]
Length = 280
Score = 347 bits (881), Expect = 8e-95
Identities = 171/276 (61%), Positives = 217/276 (77%), Gaps = 11/276 (3%)
Query: 12 AMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKV 71
AM+K + + LS+PAKN YRMV+LG+S+VGK++IVSRFL GRFED YTPTIEDFHRK
Sbjct: 5 AMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKF 64
Query: 72 YNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEV 131
Y+IRG++YQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNR+SF+EV+RL++QIL+
Sbjct: 65 YSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDT 124
Query: 132 KSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGD-ENCAYFEVSAKKNTN 190
KSCLKNKTKE ++P+VICGNK D + R+V E E LV D + CAYFE+SAKKN++
Sbjct: 125 KSCLKNKTKENVDVPLVICGNKGDR-DFYREVEQREIEQLVGDDPQRCAYFEISAKKNSS 183
Query: 191 VDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEM---------DAYG 241
+D+MF LF+MAKLP EMSP LHRK+SVQY D H + +++ DA+G
Sbjct: 184 LDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGDHGDAFG 243
Query: 242 MVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTI 277
+++PFARRPSV+SDL YI+ K QA+++++C I
Sbjct: 244 ILAPFARRPSVHSDLMYIREKTSVSSQAKDKERCVI 279
>ref|NP_033052.1| RAS, dexamethasone-induced 1 [Mus musculus]
gb|AAC53538.1| (AF009246) ras-related protein [Mus musculus]
Length = 280
Score = 346 bits (879), Expect = 1e-94
Identities = 171/276 (61%), Positives = 217/276 (77%), Gaps = 11/276 (3%)
Query: 12 AMMKTLSSGNCTLSVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKV 71
AM+K + + LS+PAKN YRMV+LG+S+VGK++IVSRFL GRFED YTPTIEDFHRK
Sbjct: 5 AMIKKMCPSDSELSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKF 64
Query: 72 YNIRGDMYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEV 131
Y+IRG++YQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNR+SF+EV+RL++QIL+
Sbjct: 65 YSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLKQQILDT 124
Query: 132 KSCLKNKTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGD-ENCAYFEVSAKKNTN 190
KSCLKNKTKE ++P+VICGNK D + R+V E E LV D + CAYFE+SAKKN++
Sbjct: 125 KSCLKNKTKENVDVPLVICGNKGDR-DFYREVEQREIEQLVGDDPQRCAYFEISAKKNSS 183
Query: 191 VDEMFYVLFSMAKLPHEMSPALHRKISVQYGDAFHPRPFCMRRVKEM---------DAYG 241
+D+MF LF+MAKLP EMSP LHRK+SVQY D H + +++ DA+G
Sbjct: 184 LDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGDHGDAFG 243
Query: 242 MVSPFARRPSVNSDLKYIKAKVLREGQARERDKCTI 277
+++PFARRPSV+SDL YI+ K QA+++++C I
Sbjct: 244 ILAPFARRPSVHSDLMYIREKTSVGSQAKDKERCVI 279
>gb|AAF50620.1| (AE003560) CG8641 gene product [Drosophila melanogaster]
Length = 434
Score = 231 bits (584), Expect = 5e-60
Identities = 129/267 (48%), Positives = 177/267 (65%), Gaps = 22/267 (8%)
Query: 22 CTLSVP-AKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQ 80
C S+P AKN YR+V+LG+SR GKSSIV+RFL RFE+ YTPTIE+FHRK+Y IR +++Q
Sbjct: 156 CDDSLPSAKNCYRLVMLGSSRAGKSSIVARFLGNRFEEAYTPTIEEFHRKLYRIRNEVFQ 215
Query: 81 LDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKN--- 137
LDILDTSG HPFPAMRRLS LTGD+FILVFS+D+RESF+EV RL++ ILE K N
Sbjct: 216 LDILDTSGYHPFPAMRRLSFLTGDLFILVFSMDSRESFEEVVRLRENILETKWAALNPGS 275
Query: 138 --KTKEAAELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYF-EVSAKKNTNVDEM 194
K K ++PM++ GNK D + V E ++G +NC F E SA++N +D++
Sbjct: 276 GFKKKSLPKIPMILAGNKCDRD--FKTVQVDEVMGYIAGQDNCCTFVECSARQNYRIDDL 333
Query: 195 FYVLFSMAKLPHEMSPALHRKISVQYG--DAFHPRPFCMRRVKE---------MDAYGMV 243
F+ LF+++ LP EM+P HR++ +G P + K+ DA G+V
Sbjct: 334 FHSLFTVSNLPLEMTPNHHRRLVSVFGAPSPLPPHGSAVGGTKKNALSIKRRFSDACGVV 393
Query: 244 SPFARRPSVNSDLKYIKAK--VLREGQ 268
+P ARRPS+ +DL +++K L EG+
Sbjct: 394 TPNARRPSIRTDLNLMRSKTMALNEGE 420
>gb|AAG17979.1|AF177335_1 (AF177335) unknown [Homo sapiens]
Length = 194
Score = 218 bits (549), Expect = 7e-56
Identities = 111/194 (57%), Positives = 144/194 (74%), Gaps = 12/194 (6%)
Query: 95 MRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICGNKN 154
MRRLSILTGDVFILVFSLDNR+SF+EV+RL++QIL+ KSCLKNKTKE ++P+VICGNK
Sbjct: 1 MRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICGNKG 60
Query: 155 DHGELCRQVPTTEAELLVSGD-ENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPALH 213
D + R+V E E LV D + CAYFE+SAKKN+++D+MF LF+MAKLP EMSP LH
Sbjct: 61 DR-DFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLH 119
Query: 214 RKISVQYGDAFHPRPFCMRRVKEM----------DAYGMVSPFARRPSVNSDLKYIKAKV 263
RK+SVQY D H + +++ DA+G+V+PFARRPSV+SDL YI+ K
Sbjct: 120 RKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKA 179
Query: 264 LREGQARERDKCTI 277
QA+++++C I
Sbjct: 180 SAGSQAKDKERCVI 193
>emb|CAB43324.1| (AL050231) /prediction=(method:""genefinder"", version:""084"",
score:""23.66"")~/prediction=(method:""genscan"",
version:""1.0"")~/match=(desc:""SIMILAR TO RAS-RELATED
PROTEIN"", species:""Caenorhabditis elegans"",
ranges:(query:48319..48486, target:S>
Length = 306
Score = 138 bits (345), Expect = 6e-32
Identities = 74/192 (38%), Positives = 119/192 (61%), Gaps = 11/192 (5%)
Query: 27 PAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDT 86
PA +++VV+G+++VGK+SI+++FL F +Y TIE+ H+ ++I G LDILDT
Sbjct: 43 PANARHKIVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDT 102
Query: 87 SGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELP 146
+G++ FPAMR LSI + D FILV+ + + +F+EV+ ++ QI ++TK +P
Sbjct: 103 AGSYEFPAMRALSISSADAFILVYDVTDATTFEEVRTIRDQI--------HETKATTAVP 154
Query: 147 MVICGNKND---HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAK 203
+V+ GNK D GE R+V E +V+ D + E SA N N+ ++F L + AK
Sbjct: 155 IVVVGNKIDLLADGETEREVEYATTESVVTVDWENGFVEASASSNENITQVFKELLAQAK 214
Query: 204 LPHEMSPALHRK 215
+ + +SPAL R+
Sbjct: 215 ITYNLSPALRRR 226
>gb|AAD13119.1| (AC006538) BC41195_1 [Homo sapiens]
Length = 198
Score = 138 bits (343), Expect = 9e-32
Identities = 76/172 (44%), Positives = 111/172 (64%), Gaps = 10/172 (5%)
Query: 30 NSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGN 89
N YR+VV GA VGKSS+V RF+ G F D Y PTIED +R+V + + L I DT+G+
Sbjct: 6 NDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGS 65
Query: 90 HPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVI 149
H FPAM+RLSI G FILVFS+ +++S +E+ + K I+++K ++ ++P+++
Sbjct: 66 HQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVE-------DIPVML 118
Query: 150 CGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSM 201
GNK D E R+V T EA+ V+ + CA+ E SAK N NV E+F L ++
Sbjct: 119 VGNKCD--ETQREVDTREAQ-AVAQEWKCAFMETSAKMNYNVKELFQELLTL 167
>pir||T15833 hypothetical protein C54A12.4 - Caenorhabditis elegans
gb|AAA68305.1| (U28733) similar to RAS-related proteins [Caenorhabditis elegans]
Length = 219
Score = 128 bits (319), Expect = 6e-29
Identities = 72/180 (40%), Positives = 109/180 (60%), Gaps = 9/180 (5%)
Query: 25 SVPAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNI-RGDMYQLDI 83
S + + YR+ V GA VGKSSI RF+ G F + Y PTIED +R+V + + ++ L I
Sbjct: 24 SEASTSDYRVAVFGAGGVGKSSITQRFVKGTFNENYVPTIEDTYRQVISCNQKNVCTLQI 83
Query: 84 LDTSGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAA 143
DT+G+H FPAM+RLSI G+ FIL++S+ N++SF E+ + + + EVK A
Sbjct: 84 TDTTGSHQFPAMQRLSISKGNAFILIYSVTNKQSFAELVPIIEMMKEVKG------NAIA 137
Query: 144 ELPMVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAK 203
E P+++ GNK D E R+V + + + + E C + E SAK N N+ E+F L ++ K
Sbjct: 138 ETPIMLVGNKKDE-ESKREVSSNSGQKVATNME-CGFIETSAKNNENITELFQQLLALEK 195
>gb|AAF54453.1| (AE003684) CG8500 gene product [Drosophila melanogaster]
Length = 233
Score = 127 bits (316), Expect = 1e-28
Identities = 70/174 (40%), Positives = 105/174 (60%), Gaps = 7/174 (4%)
Query: 30 NSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGN 89
N YR+VV GA VGKSS+V RF+ G F + Y PTIED +R+V + ++ L I DT+G+
Sbjct: 17 NDYRVVVFGAGGVGKSSLVLRFIKGTFRESYIPTIEDTYRQVISCNKNICTLQITDTTGS 76
Query: 90 HPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVI 149
H FPAM+RLSI G FILV+S+ +++S +E++ + I E+K + +P+++
Sbjct: 77 HQFPAMQRLSISKGHAFILVYSVCSKQSLEELRPIWALIKELKGA------DIPNIPVML 130
Query: 150 CGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAK 203
GNK D R+V E + + + ++ E SAK N NV E+F L +M K
Sbjct: 131 VGNKCDETAELREVSQAEGQAQAT-TWSISFMETSAKTNHNVTELFQELLNMEK 183
>gb|AAF45493.1| (AE003417) EG:BACR37P7.8 gene product [Drosophila melanogaster]
Length = 319
Score = 126 bits (314), Expect = 2e-28
Identities = 71/192 (36%), Positives = 116/192 (59%), Gaps = 14/192 (7%)
Query: 27 PAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDT 86
PA +++VV+G+++VGK+SI+++FL F +Y TIE+ H+ ++I G LDILDT
Sbjct: 59 PANARHKIVVMGSAKVGKTSIITQFLYNTFSTKYKRTIEEMHQGNFSIAGVSLTLDILDT 118
Query: 87 SGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELP 146
+G++ MR LSI + D FILV+ + + +F+EV+ ++ QI ++TK +P
Sbjct: 119 AGSY---EMRALSISSADAFILVYDVTDATTFEEVRTIRDQI--------HETKATTAVP 167
Query: 147 MVICGNKND---HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAK 203
+V+ GNK D GE R+V E +V+ D + E SA N N+ ++F L + AK
Sbjct: 168 IVVVGNKIDLLADGETEREVEYATTESVVTVDWENGFVEASASSNENITQVFKELLAQAK 227
Query: 204 LPHEMSPALHRK 215
+ + +SPAL R+
Sbjct: 228 ITYNLSPALRRR 239
>ref|NP_006261.1| related RAS viral (r-ras) oncogene homolog; Oncogene RRAS [Homo
sapiens]
sp|P10301|RRAS_HUMAN RAS-RELATED PROTEIN R-RAS (P23)
pir||TVHURR transforming protein R-ras - human
gb|AAA60256.1| (M14949) R-ras [Homo sapiens]
Length = 218
Score = 120 bits (299), Expect = 1e-26
Identities = 70/169 (41%), Positives = 100/169 (58%), Gaps = 10/169 (5%)
Query: 27 PAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDT 86
P ++++VV+G VGKS++ +F+ F Y PTIED + K+ ++ G +LDILDT
Sbjct: 25 PPSETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDT 84
Query: 87 SGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELP 146
+G F AMR + G F+LVF++++R+SF+EV +L QIL V K+ + P
Sbjct: 85 AGQEEFGAMREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRV--------KDRDDFP 136
Query: 147 MVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 195
+V+ GNK D E RQVP +EA + AYFE SAK NVDE F
Sbjct: 137 VVLVGNKADL-ESQRQVPRSEASAF-GASHHVAYFEASAKLRLNVDEAF 183
>sp|P18613|RAP1_DICDI RAS-RELATED PROTEIN RAP-1
pir||S11229 GTP-binding protein rap1 - slime mold (Dictyostelium discoideum)
emb|CAA38185.1| (X54291) ras-related protein (AA 1-186) [Dictyostelium discoideum]
Length = 186
Score = 120 bits (299), Expect = 1e-26
Identities = 67/180 (37%), Positives = 105/180 (58%), Gaps = 11/180 (6%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
+++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + + L+ILDT+G
Sbjct: 6 FKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDSNQCMLEILDTAGTEQ 65
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F+LV+S+ + +F+E+ L++QIL VK C ++PMV+ G
Sbjct: 66 FTAMRDLYMKNGQGFVLVYSIISNSTFNELPDLREQILRVKDC--------EDVPMVLVG 117
Query: 152 NKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSP 210
NK D H + R + T + E L +C + E SAK NV+++FY L + + P
Sbjct: 118 NKCDLHDQ--RVISTEQGEELARKFGDCYFLEASAKNKVNVEQIFYNLIRQINRKNPVGP 175
>gb|AAB58345.1| (AF000653) Pprap1 protein [Physarum polycephalum]
Length = 184
Score = 120 bits (298), Expect = 2e-26
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
+++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + G L+ILDT+G
Sbjct: 2 FKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQ 61
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F+LV+S+ +F+++ L++QIL VK C ++PMV+ G
Sbjct: 62 FTAMRDLYMKNGQGFVLVYSIIAMSTFNDLPDLREQILRVKDC--------DDVPMVLVG 113
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R + T + + L CA+ E SAK NV+++FY L
Sbjct: 114 NKCDLAEQ-RVISTEQGDELARKFGGCAFLEASAKNKINVEQIFYDL 159
>sp|Q94694|RAP1_PHYPO RAS-RELATED PROTEIN RAP-1 (PPRAP1)
pir||S65761 ras-related GTP-binding protein Pprap1 - slime mold (Physarum
polycephalum)
gb|AAC47511.1| (U15594) proPprap1 protein [Physarum polycephalum]
prf||2206301A Pprap1 gene [Physarum polycephalum]
Length = 188
Score = 120 bits (298), Expect = 2e-26
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
+++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + G L+ILDT+G
Sbjct: 6 FKIVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQ 65
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F+LV+S+ +F+++ L++QIL VK C ++PMV+ G
Sbjct: 66 FTAMRDLYMKNGQGFVLVYSIIAMSTFNDLPDLREQILRVKDC--------DDVPMVLVG 117
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R + T + + L CA+ E SAK NV+++FY L
Sbjct: 118 NKCDLAEQ-RVISTEQGDELARKFGGCAFLEASAKNKINVEQIFYDL 163
>pdb|1KAO| Crystal Structure Of The Small G Protein Rap2a With Gdp
pdb|3RAP|R Chain R, The Small G Protein Rap2 In A Non Catalytic Complex With
Gtp
pdb|3RAP|S Chain S, The Small G Protein Rap2 In A Non Catalytic Complex With
Gtp
pdb|2RAP| The Small G Protein Rap2a In Complex With Gtp
Length = 167
Score = 119 bits (295), Expect = 4e-26
Identities = 68/164 (41%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F +MR L I G FILV+SL N++SF ++K ++ QI+ VK K +P+++ G
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEK--------VPVILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 195
NK D E R+V ++E L + C + E SAK T VDE+F
Sbjct: 116 NKVDL-ESEREVSSSEGRALAE-EWGCPFMETSAKSKTMVDELF 157
>ref|NP_066361.1| RAP2A, member of RAS oncogene family; RAP2, member of RAS oncogene
family (K-rev); K-REV [Homo sapiens]
sp|P10114|RAP2_HUMAN RAS-RELATED PROTEIN RAP-2A
pir||S03180 transforming protein rap2 - human
emb|CAA31052.1| (X12534) rap2 protein (AA 1-183) [Homo sapiens]
Length = 183
Score = 119 bits (295), Expect = 4e-26
Identities = 68/164 (41%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F +MR L I G FILV+SL N++SF ++K ++ QI+ VK K +P+++ G
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRVKRYEK--------VPVILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 195
NK D E R+V ++E L + C + E SAK T VDE+F
Sbjct: 116 NKVDL-ESEREVSSSEGRALAE-EWGCPFMETSAKSKTMVDELF 157
>ref|NP_002877.1| RAP2B, member of RAS oncogene family [Homo sapiens]
sp|P17964|RAP3_HUMAN RAS-RELATED PROTEIN RAP-2B
pir||TVHUR2 transforming protein rap2b - human
emb|CAA37178.1| (X52987) rap2b gene product (AA 1-183) [Homo sapiens]
Length = 183
Score = 118 bits (293), Expect = 7e-26
Identities = 68/165 (41%), Positives = 100/165 (60%), Gaps = 12/165 (7%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGSFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F +MR L I G FILV+SL N++SF ++K ++ QI+ V K +PM++ G
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIIRV--------KRYERVPMILVG 115
Query: 152 NKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 195
NK D GE R+V E + L + +C + E SAK +VDE+F
Sbjct: 116 NKVDLEGE--REVSYGEGKALAE-EWSCPFMETSAKNKASVDELF 157
>sp|P22126|RAS1_NEUCR RAS-1 PROTEIN
pir||S12892 transforming protein (ras) - Neurospora crassa
emb|CAA37612.1| (X53533) NC-ras protein [Neurospora crassa]
dbj|BAA32498.1| (AB016991) NC-ras [Neurospora crassa]
prf||1701291A NC-ras protein [Neurospora crassa]
Length = 213
Score = 118 bits (293), Expect = 7e-26
Identities = 70/168 (41%), Positives = 99/168 (58%), Gaps = 12/168 (7%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS + + + G F D+Y PTIED +RK I ++ LDILDT+G
Sbjct: 9 YKLVVVGGGGVGKSCLTIQLIQGHFLDEYDPTIEDSYRKQCTIDNEVALLDILDTAGQEE 68
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+LVF++++RESF+E++ Q+QIL V K+ PM+I G
Sbjct: 69 YSAMREQYMRTGEGFLLVFAINSRESFEEIRIYQQQILRV--------KDRDSFPMIIVG 120
Query: 152 NKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D GE R V E + L + + Y E SAK NV+ FY L
Sbjct: 121 NKYDLRGE--RVVSEQEGQAL-AAEFGTKYIETSAKTQHNVENAFYDL 165
>sp|O42785|RASL_COLTR RAS-LIKE PROTEIN
gb|AAC03781.1| (AF044895) Ras homolog [Colletotrichum trifolii]
Length = 214
Score = 117 bits (290), Expect = 2e-25
Identities = 68/166 (40%), Positives = 96/166 (56%), Gaps = 12/166 (7%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS + + + F D+Y PTIED +RK I ++ LD+LDT+G
Sbjct: 9 YKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDEEVALLDVLDTAGQEE 68
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+LV+S+ +R+SF+E+ Q+QIL V K+ PMV+ G
Sbjct: 69 YSAMREQYMRTGEGFLLVYSITSRQSFEEITTFQQQILRV--------KDKDYFPMVVVG 120
Query: 152 NKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFY 196
NK D GE R+V E E L C + E SAK NVD+ FY
Sbjct: 121 NKCDLEGE--REVTRQEGEALAK-SFGCKFIETSAKSRINVDKAFY 163
>sp|P38976|RAS2_HYDMA RAS-LIKE PROTEIN RAS2
pir||S32042 GTP-binding protein ras2 - Hydra magnipapillata
pir||JC4573 GTP-binding protein ras2 - Hydra magnipapillata
emb|CAA50187.1| (X70839) RAS2 protein [Hydra magnipapillata]
prf||2204244A ras 2 gene [Hydra magnipapillata]
Length = 192
Score = 117 bits (290), Expect = 2e-25
Identities = 72/167 (43%), Positives = 96/167 (57%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS++ +F+ F Y PTIED +RK I + LDILDT+G
Sbjct: 9 YKLVVVGGGGVGKSALTIQFIQSHFVQDYDPTIEDSYRKQCVIDDKVAHLDILDTAGQEE 68
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR + TG+ F+LVFS+ +R SFDE+ R QIL V K+ E PM++ G
Sbjct: 69 FSAMRDEYMRTGEGFLLVFSVTDRSSFDEIPRFHTQILRV--------KDIEEFPMILVG 120
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK+D E R V T EA+ L +Y E SAK+ NVD F+ L
Sbjct: 121 NKSDL-ENERTVSTAEAQEL-GRKLKVSYLESSAKQRINVDAAFHDL 165
>ref|NP_067006.1| hypothetical protein similar to small G proteins, especially RAP-2A
[Homo sapiens]
emb|CAB41256.1| (AL049685) hypothetical protein [Homo sapiens]
Length = 183
Score = 116 bits (289), Expect = 2e-25
Identities = 67/164 (40%), Positives = 100/164 (60%), Gaps = 10/164 (6%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIEDF+RK + L+ILDT+G
Sbjct: 4 YKVVVLGSGGVGKSALTVQFVTGTFIEKYDPTIEDFYRKEIEVDSSPSVLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F +MR L I G FILV+SL N++SF ++K ++ QI+ VK K +P+++ G
Sbjct: 64 FASMRDLYIKNGQGFILVYSLVNQQSFQDIKPMRDQIVRVKRYEK--------VPLILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 195
NK D E R+V ++E L + C + E SAK + VDE+F
Sbjct: 116 NKVDL-EPEREVMSSEGRALAQ-EWGCPFMETSAKSKSMVDELF 157
>sp|P87018|RAS_BOTCI RAS-LIKE PROTEIN
gb|AAB51236.1| (U79558) Ras protein [Botryotinia fuckeliana]
Length = 212
Score = 116 bits (289), Expect = 2e-25
Identities = 67/166 (40%), Positives = 97/166 (58%), Gaps = 12/166 (7%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS + + + F D+Y PTIED +RK I ++ LD+LDT+G
Sbjct: 9 YKLVVVGGGGVGKSCLTIQLIQSHFVDEYDPTIEDSYRKQCVIDEEVALLDVLDTAGQEE 68
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+LV+S+ +R+SF+E+ Q+QIL V K+ P+++ G
Sbjct: 69 YSAMREQYMRTGEGFLLVYSITSRQSFEEIMTFQQQILRV--------KDKDYFPIIVVG 120
Query: 152 NKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFY 196
NK D GE RQV E + L + D C + E SAK NVD FY
Sbjct: 121 NKCDLEGE--RQVSKQEGQQL-ADDFGCKFIETSAKSRINVDNAFY 163
>sp|P34729|RAS1_PHYPO RAS-LIKE PROTEIN 1
pir||S33796 ras protein homolog - slime mold (Physarum polycephalum)
gb|AAB05646.1| (L10344) ras1 protein [Physarum polycephalum]
gb|AAB06296.1| (U10905) Ppras1 protein precursor [Physarum polycephalum]
Length = 189
Score = 116 bits (289), Expect = 2e-25
Identities = 68/168 (40%), Positives = 98/168 (57%), Gaps = 12/168 (7%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++V++G VGKS++ + + F D+Y PTIED +RK I + LDILDT+G
Sbjct: 4 YKLVIVGGGGVGKSALTIQLIQNHFIDEYDPTIEDSYRKQVTIDEETCLLDILDTAGQEE 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG F+ V+S+ +R SFDE+ ++QIL V K+ ++PM++ G
Sbjct: 64 YSAMRDQYMRTGQGFLCVYSITSRSSFDEIASFREQILRV--------KDKDKVPMIVVG 115
Query: 152 NKND-HGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D GE RQV T E + L + C + E SAK NV+E FY L
Sbjct: 116 NKCDLEGE--RQVTTGEGQDL-ARSFGCPFMETSAKSRVNVEESFYQL 160
>sp|P34726|RAS2_PHYPO RAS-LIKE PROTEIN 2
pir||S38362 Ppras2 protein - slime mold (Physarum polycephalum)
gb|AAC37179.1| (L14275) membrane protein [Physarum polycephalum]
gb|AAB58748.3| (AF189162) Ppras2 protein [Physarum polycephalum]
Length = 193
Score = 116 bits (287), Expect = 3e-25
Identities = 68/171 (39%), Positives = 97/171 (55%), Gaps = 10/171 (5%)
Query: 28 AKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTS 87
A+ Y++V++G VGKS++ + + F D+Y PTIED +RK I + LDILDT+
Sbjct: 2 AQLEYKLVIVGGGGVGKSALTIQLIQNHFIDEYDPTIEDSYRKQVVIDEETCLLDILDTA 61
Query: 88 GNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPM 147
G + AMR + TG F++V+S+ +R SFDE+ ++QIL V K+ +PM
Sbjct: 62 GQEEYSAMRDQYMRTGQGFVMVYSITSRSSFDEINAFREQILRV--------KDKDTVPM 113
Query: 148 VICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
V+ GNK D RQV T E + L C + E SAK NV+E FY L
Sbjct: 114 VLAGNKCDLASE-RQVTTNEGQELARA-FGCPFVETSAKARLNVEECFYGL 162
>sp|P03967|RASD_DICDI RAS-LIKE PROTEIN RASD (TRANSFORMING PROTEIN P23)
emb|CAA77848.1| (Z11804) ras protein [Dictyostelium discoideum]
Length = 187
Score = 116 bits (287), Expect = 3e-25
Identities = 65/167 (38%), Positives = 96/167 (56%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++V++G VGKS++ + + F D+Y PTIED +RK +I + LDILDT+G
Sbjct: 4 YKLVIVGGGGVGKSALTIQLIQNHFIDEYDPTIEDSYRKQVSIDDETCLLDILDTAGQEE 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG F+ V+S+ +R S+DE+ ++QIL V K+ +P+++ G
Sbjct: 64 YSAMRDQYMRTGQGFLCVYSITSRSSYDEIASFREQILRV--------KDKDRVPLILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D RQV E + L G NC + E SAK NV+E FY L
Sbjct: 116 NKADLDHE-RQVSVNEGQELAKG-FNCPFMESSAKSRINVEEAFYSL 160
>pir||A61216 transforming protein rap1b - rat (strain Copenhagen)
Length = 184
Score = 115 bits (286), Expect = 5e-25
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTDDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWSNCAFLESSAKSKINVNEIFYDL 161
>ref|NP_033127.1| Harvey rat sarcoma oncogene, subgroup R [Mus musculus]
sp|P10833|RRAS_MOUSE RAS-RELATED PROTEIN R-RAS (P23)
gb|AAA40038.1| (M21019) R-ras [Mus musculus]
Length = 218
Score = 115 bits (286), Expect = 5e-25
Identities = 69/169 (40%), Positives = 99/169 (57%), Gaps = 10/169 (5%)
Query: 27 PAKNSYRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDT 86
P ++++VV+G VGKS++ +F+ F Y PTIED + K+ + G +LDILDT
Sbjct: 25 PPGETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICTVDGIPARLDILDT 84
Query: 87 SGNHPFPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELP 146
+G F AMR + G+ F+LVF++++R+SF+EV +L QIL V K+ + P
Sbjct: 85 AGQEEFGAMREQYMRAGNGFLLVFAINDRQSFNEVGKLFTQILRV--------KDRDDFP 136
Query: 147 MVICGNKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMF 195
+V+ GNK D E RQV +EA S + YFE SAK NVDE F
Sbjct: 137 IVLVGNKADL-ENQRQVLRSEASSF-SASHHMTYFEASAKLRLNVDEAF 183
>ref|NP_056461.1| RAP1B, member of RAS oncogene family; RAS-related protein RAP1B;
K-REV [Homo sapiens]
sp|P09526|RAPB_HUMAN RAS-RELATED PROTEIN RAP-1B (GTP-BINDING PROTEIN SMG P21B)
pir||TVHUR1 transforming protein rap1b - human
pir||A34655 transforming protein rap1b - bovine
gb|AAA30763.1| (M33141) GTP-binding protein (smg p21B) [Bos taurus]
emb|CAB45777.1| (AL080212) hypothetical protein [Homo sapiens]
emb|CAB46488.1| (X08004) Rap1B protein [Homo sapiens]
Length = 184
Score = 115 bits (286), Expect = 5e-25
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTDDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDL 161
>gb|AAF17287.1|U45968_1 (U45968) G-protein [Oncorhynchus mykiss]
Length = 187
Score = 115 bits (285), Expect = 6e-25
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 11/167 (6%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+ VF+++N +SF++V ++QI N+ K++ +PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNIKSFEDVHLYREQI--------NRVKDSDSVPMVLVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK+D G R V + +A+ L G + E SAK V+E FY L
Sbjct: 116 NKSDLGS--RSVESRQAQELARG-YGVPFVETSAKTRQGVEEAFYSL 159
>gb|AAF17286.1|U45967_1 (U45967) G-protein [Oncorhynchus mykiss]
Length = 187
Score = 115 bits (285), Expect = 6e-25
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 11/167 (6%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+GA VGKS++ + + F D+Y PTIED +RK I G+ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEE 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+ VF+++N +SF++V ++QI N+ K++ +PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAINNIKSFEDVHLYREQI--------NRVKDSDSVPMVLVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK+D G R V + +A+ L G + E SAK V+E FY L
Sbjct: 116 NKSDLGS--RSVESRQAQELARG-YGVPFVETSAKTRQGVEEAFYSL 159
>pdb|1GUA|A Chain A, Human Rap1a, Residues 1-167, Double Mutant (E30d,K31e)
Complexed With Gppnhp And The Ras-Binding-Domain Of
Human C-Raf1, Residues 51-131
Length = 167
Score = 115 bits (285), Expect = 6e-25
Identities = 67/167 (40%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F D+Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVDEYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDL 161
>sp|P22279|RAS2_RHIRA RAS-LIKE PROTEIN 2
gb|AAA83994.1| (M55176) MRAS2 gene product [Mucor racemosus]
Length = 198
Score = 115 bits (284), Expect = 8e-25
Identities = 64/167 (38%), Positives = 98/167 (58%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++V++G VGKS++ +F+ F D+Y PTIED +RK I + LDILDT+G
Sbjct: 12 YKIVMVGDGGVGKSAMTIQFIQSTFVDEYDPTIEDSYRKQCLIDSECAMLDILDTAGQEE 71
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + G+ F+L++S+ + +F++V++L +QI V K+ PMV+ G
Sbjct: 72 YSAMRERFMRNGEGFVLIYSITSYHTFEQVQKLHEQIARV--------KDLEHFPMVLVG 123
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E RQVPT+ L NC +FE SAK+N + + F+ L
Sbjct: 124 NKCDL-EQDRQVPTSAGRDLAK-QYNCQFFEASAKQNVRIQDAFHGL 168
>sp|P08645|RAS3_DROME RAS-LIKE PROTEIN 3 (ROUGHENED PROTEIN)
pir||A41217 transforming protein (rap1) - fruit fly (Drosophila melanogaster)
gb|AAA28845.1| (M80535) GTP-binding protein [Drosophila melanogaster]
gb|AAF15520.1|AF186654_1 (AF186654) roughened [Drosophila melanogaster]
gb|AAF15521.1|AF186655_1 (AF186655) roughened [Drosophila simulans]
gb|AAF15522.1|AF186656_1 (AF186656) roughened [Drosophila mauritiana]
gb|AAF47583.1| (AE003473) R gene product [Drosophila melanogaster]
Length = 184
Score = 115 bits (284), Expect = 8e-25
Identities = 65/167 (38%), Positives = 101/167 (59%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ F ++Y PTIED +RK + G L+ILDT+G
Sbjct: 4 YKIVVLGSGGVGKSALTVQFVQCIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F+LV+S+ + +F++++ L++QIL V K+ ++PMV+ G
Sbjct: 64 FTAMRDLYMKNGQGFVLVYSITAQSTFNDLQDLREQILRV--------KDTDDVPMVLVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E +V E ++ NCA+ E SAK NV+++FY L
Sbjct: 116 NKCDLEE--ERVVGKELGKNLATQFNCAFMETSAKAKVNVNDIFYDL 160
>gb|AAD10840.1| (U53783) Rap1b [Cyprinus carpio]
Length = 184
Score = 114 bits (283), Expect = 1e-24
Identities = 65/167 (38%), Positives = 101/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + G L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDGQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++P+++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTDDVPIILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L +CA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWNSCAFLESSAKSKINVNEIFYDL 161
>pir||JC5155 rap1A protein - turkey
emb|CAA59757.1| (X85756) turkey RAP1Ab [Meleagris gallopavo]
emb|CAA59756.1| (X85755) turkey RAP1Aa [Meleagris gallopavo]
Length = 184
Score = 114 bits (283), Expect = 1e-24
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDLEEE-RVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDL 161
>gb|AAF03566.1|AF134251_1 (AF134251) Ras homolog type A [Candida albicans]
Length = 289
Score = 114 bits (282), Expect = 1e-24
Identities = 65/167 (38%), Positives = 98/167 (57%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS++ + + F D+Y PTIED +RK I LD+LDT+G
Sbjct: 5 YKLVVVGGGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKQCTIDDQQVLLDVLDTAGQEE 64
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+LV+S+++ SF E+ QIL V K++ +P+++ G
Sbjct: 65 YSAMREQYMRTGEGFLLVYSINSLNSFQELNSFYDQILRV--------KDSDNVPVLVVG 116
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E+ RQV + E L ++ NC + E SAK+ NV+E FY L
Sbjct: 117 NKCDL-EMERQV-SYEDGLALANSFNCPFLETSAKQRINVEEAFYGL 161
>gb|AAD52662.1|AF177670_1 (AF177670) Ras1p [Candida albicans]
gb|AAF03567.1|AF134252_1 (AF134252) Ras homolog type B [Candida albicans]
Length = 290
Score = 114 bits (282), Expect = 1e-24
Identities = 65/167 (38%), Positives = 98/167 (57%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS++ + + F D+Y PTIED +RK I LD+LDT+G
Sbjct: 5 YKLVVVGGGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKQCTIDDQQVLLDVLDTAGQEE 64
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+LV+S+++ SF E+ QIL V K++ +P+++ G
Sbjct: 65 YSAMREQYMRTGEGFLLVYSINSLNSFQELNSFYDQILRV--------KDSDNVPVLVVG 116
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E+ RQV + E L ++ NC + E SAK+ NV+E FY L
Sbjct: 117 NKCDL-EMERQV-SYEDGLALANSFNCPFLETSAKQRINVEEAFYGL 161
>sp|P22123|RAPA_DISOM RAS-RELATED PROTEIN O-KREV
gb|AAA49226.1| (M38395) GTP-binding protein [Discopyge ommata]
Length = 184
Score = 114 bits (282), Expect = 1e-24
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQPCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDL 161
>pir||F38625 GTP-binding protein o-Krev - electric ray (Discopyge ommata)
Length = 184
Score = 114 bits (282), Expect = 1e-24
Identities = 65/167 (38%), Positives = 100/167 (58%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQPCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D + R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDLRDE-RVVGKEQGQNLARQWNNCAFLESSAKSKINVNEIFYDL 161
>sp|P08647|RAS_SCHPO RAS-LIKE PROTEIN 1
pir||T37875 ras-like protein 1 - fission yeast (Schizosaccharomyces pombe)
emb|CAB11218.1| (Z98597) ras-like protein 1. [Schizosaccharomyces pombe]
Length = 219
Score = 113 bits (281), Expect = 2e-24
Identities = 67/167 (40%), Positives = 94/167 (56%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS++ + + F D+Y PTIED +RK I G+ LD+LDT+G
Sbjct: 9 YKLVVVGDGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEE 68
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+LV+++ +R SFDE+ +QIL V K+ P+V+
Sbjct: 69 YSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRV--------KDKDTFPVVLVA 120
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V E E L +C Y E SAK NV+E FY L
Sbjct: 121 NKCDL-EAERVVSRAEGEQLAK-SMHCLYVETSAKLRLNVEEAFYSL 165
>pir||TVBYPR transforming protein ras - fission yeast (Schizosaccharomyces
pombe)
emb|CAA27399.1| (X03771) put. ras protein [Schizosaccharomyces pombe]
Length = 214
Score = 113 bits (281), Expect = 2e-24
Identities = 67/167 (40%), Positives = 94/167 (56%), Gaps = 10/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS++ + + F D+Y PTIED +RK I G+ LD+LDT+G
Sbjct: 4 YKLVVVGDGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGALLDVLDTAGQEE 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+LV+++ +R SFDE+ +QIL V K+ P+V+
Sbjct: 64 YSAMREQYMRTGEGFLLVYNITSRSSFDEISTFYQQILRV--------KDKDTFPVVLVA 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V E E L +C Y E SAK NV+E FY L
Sbjct: 116 NKCDL-EAERVVSRAEGEQLAK-SMHCLYVETSAKLRLNVEEAFYSL 160
>pdb|1C1Y|A Chain A, Crystal Structure Of Rap.Gmppnp In Complex With The Ras-
Binding-Domain Of C-Raf1 Kinase (Rafrbd)
Length = 167
Score = 113 bits (280), Expect = 2e-24
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDL 161
>ref|NP_002875.1| RAP1A, member of RAS oncogene family; RAS-related protein RAP1A
[Homo sapiens]
sp|P10113|RAPA_HUMAN RAS-RELATED PROTEIN RAP-1A (C21KG) (KREV-1 PROTEIN) (GTP-BINDING
PROTEIN SMG-P21A) (G-22K)
pir||A31961 transforming protein rap1A - bovine
pir||A32342 transforming protein rap1a - human
emb|CAA31051.1| (X12533) rap1A protein (AA 1-184) [Homo sapiens]
gb|AAA30415.1| (J04196) GTP-binding protein [Bos taurus]
gb|AAA36150.1| (M22995) ras-related protein [Homo sapiens]
emb|CAB55685.1| (AL049557) dJ773A18.1 (RAS-RELATED PROTEIN RAP-1A (C21KG) (KREV-1
PROTEIN) (GTP-BINDING PROTEIN SMG-P21A) (G-22K).) [Homo
sapiens]
Length = 184
Score = 113 bits (280), Expect = 2e-24
Identities = 66/167 (39%), Positives = 100/167 (59%), Gaps = 9/167 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VVLG+ VGKS++ +F+ G F ++Y PTIED +RK + L+ILDT+G
Sbjct: 4 YKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDCQQCMLEILDTAGTEQ 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR L + G F LV+S+ + +F++++ L++QIL V K+ ++PM++ G
Sbjct: 64 FTAMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRV--------KDTEDVPMILVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D E R V + + L NCA+ E SAK NV+E+FY L
Sbjct: 116 NKCDL-EDERVVGKEQGQNLARQWCNCAFLESSAKSKINVNEIFYDL 161
>gb|AAB09439.1| (U53177) Psmras1 [Schistosoma mansoni]
Length = 184
Score = 113 bits (279), Expect = 3e-24
Identities = 65/167 (38%), Positives = 101/167 (59%), Gaps = 11/167 (6%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+GA VGKS++ + + F ++Y PTIED +RK I G++ LDILDT+G
Sbjct: 4 YKLVVVGAGGVGKSALTIQLIQNHFVEEYDPTIEDSYRKQMVIDGEICLLDILDTAGQEE 63
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG+ F+ VF+++N +S+D++ + ++QI + K+A E+PMV+ G
Sbjct: 64 YSAMRDQYMRTGEGFLCVFAVNNSKSYDDINQYREQI--------KRVKDADEVPMVLVG 115
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVL 198
NK D R V T EA+ L + N Y E SAK V++ F+ L
Sbjct: 116 NKVDLTN--RSVCTEEAKSL-AHSYNIPYVETSAKTRQGVEDAFHKL 159
>emb|CAA26191.1| (X02331) SPRAS-protein [Schizosaccharomyces pombe]
Length = 219
Score = 113 bits (279), Expect = 3e-24
Identities = 71/189 (37%), Positives = 101/189 (52%), Gaps = 11/189 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++VV+G VGKS++ + + F D+Y PTIED +RK I G+ LD+LDT+G
Sbjct: 9 YKLVVVGDGGVGKSALTIQLIQSHFVDEYDPTIEDSYRKKCEIDGEGAVLDLLDTAGQEE 68
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
+ AMR + TG F+LV+++ +R SFDE+ +QIL V K+ P+V+
Sbjct: 69 YSAMREQYMRTGQGFLLVYNITSRSSFDEISTFYQQILRV--------KDKDTFPVVLVA 120
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLF-SMAKLPHEMSP 210
NK D E R V E E L +C Y E SAK NV+E FY L ++ +
Sbjct: 121 NKCDL-EAERVVSRREREQLAK-SMHCLYVETSAKLRLNVEEAFYSLVRTIRRYNKSEEK 178
Query: 211 ALHRKISVQ 219
H K +VQ
Sbjct: 179 GFHNKQAVQ 187
>ref|NP_062666.1| GTP-binding protein ROC2 [Mus musculus]
gb|AAD13022.1| (AF084463) GTP-binding protein ROC2 [Mus musculus]
Length = 217
Score = 112 bits (278), Expect = 4e-24
Identities = 66/185 (35%), Positives = 105/185 (56%), Gaps = 10/185 (5%)
Query: 32 YRMVVLGASRVGKSSIVSRFLNGRFEDQYTPTIEDFHRKVYNIRGDMYQLDILDTSGNHP 91
Y++V+LGA VGKS++ +F++ +F D + PTIED ++ I + LDILDT+G
Sbjct: 21 YKVVMLGAGGVGKSAVTMQFISHQFPDYHDPTIEDAYKTQVRIDNEPAYLDILDTAGQAE 80
Query: 92 FPAMRRLSILTGDVFILVFSLDNRESFDEVKRLQKQILEVKSCLKNKTKEAAELPMVICG 151
F AMR + G+ FI+ +S+ +R+SF E + ++ I +V + E+P+V+ G
Sbjct: 81 FTAMREQYMRGGEGFIICYSVTDRQSFQEAAKFKELIFQV--------RHTYEIPLVLVG 132
Query: 152 NKNDHGELCRQVPTTEAELLVSGDENCAYFEVSAKKNTNVDEMFYVLFSMAKLPHEMSPA 211
NK D E RQV +TE + ++ D NCA+FE SA +D+ F L + M
Sbjct: 133 NKIDL-EQFRQV-STEEGMTLARDYNCAFFETSAALRFGIDDAFQGLVREIRRKESMLSL 190
Query: 212 LHRKI 216
+ RK+
Sbjct: 191 VERKL 195
Database: nr
Number of letters in database: 182,691,300
Number of sequences in database: 580,189
Lambda K H
0.321 0.135 0.391
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 98355246
Number of Sequences: 580189
Number of extensions: 4012124
Number of successful extensions: 12523
Number of sequences better than 10.0: 1284
Number of HSP's better than 10.0 without gapping: 708
Number of HSP's successfully gapped in prelim test: 576
Number of HSP's that attempted gapping in prelim test: 10619
Number of HSP's gapped (non-prelim): 1305
length of query: 278
length of database: 182,691,300
effective HSP length: 56
effective length of query: 222
effective length of database: 150,200,716
effective search space: 33344558952
effective search space used: 33344558952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 70 (31.7 bits)
