Score E
Sequences producing significant alignments: (bits) Value
ref|NP_004360.1| collagen, type VI, alpha 3 [Homo sapiens] ... 3972 0.0
gb|AAD01978.1| (AF034136) collagen alpha3(VI) [Mus musculus] 2721 0.0
sp|P15989|CA36_CHICK COLLAGEN ALPHA 3(VI) CHAIN PRECURSOR >... 2606 0.0
gb|AAC23667.1| (AF064749) type VI collagen alpha 3 subunit ... 2197 0.0
pir||S32605 collagen alpha 3(VI) chain - mouse (fragment) >... 704 0.0
pir||S28776 collagen alpha 3(VI) chain - human (fragment) >... 406 e-111
gb|AAG28506.1|AF197573_1 (AF197573) type VI collagen alpha ... 397 e-108
gb|AAF79924.1|AF129288_1 (AF129288) type VI collagen alpha ... 387 e-106
gb|AAC23668.1| (AF064750) type VI collagen alpha 3 subunit ... 274 1e-71
gb|AAF19243.1|AC007363_1 (AC007363) similar to Coch-5B2 [Ho... 179 4e-43
gb|AAD04919.1| (AF099154) von Willebrand factor [Canis fami... 171 1e-40
gb|AAB93766.1| (U66246) von Willebrand factor [Canis famili... 171 1e-40
sp|Q28295|VWF_CANFA VON WILLEBRAND FACTOR PRECURSOR (VWF) >... 171 1e-40
gb|AAC06229.1| (AF052036) von Willebrand factor precursor [... 166 5e-39
gb|AAA61295.1| (M60675) von Willebrand factor [Homo sapiens] 162 7e-38
gb|AAB59512.1| (M10321) von Willebrand factor prepropeptide... 162 7e-38
ref|NP_000543.1| von Willebrand factor precursor; Coagulati... 162 7e-38
emb|CAA27972.1| (X04385) VWF pre-pro-polypeptide (-22 to 27... 162 7e-38
sp|O42163|COCH_CHICK COCHLIN PRECURSOR (COCH-5B2) >gi|22935... 156 3e-36
ref|NP_004077.1| cochlin precursor; cochlin; coagulation fa... 155 7e-36
ref|NP_031754.1| coagulation factor C homolog (Limulus poly... 151 1e-34
sp|Q91145|CA1C_NOTVI COLLAGEN ALPHA 1(XII) CHAIN >gi|211917... 150 2e-34
pir||S31211 collagen alpha 1(XIV) chain precursor - chicken 149 5e-34
pir||S31212 collagen alpha 1(XIV) chain precursor, short fo... 149 5e-34
sp|P32018|CA1E_CHICK COLLAGEN ALPHA 1(XIV) CHAIN PRECURSOR ... 149 5e-34
ref|NP_031756.1| procollagen, type XII, alpha 1 [Mus muscul... 148 9e-34
ref|NP_004361.1| collagen, type XII, alpha 1 [Homo sapiens]... 148 1e-33
emb|CAA72402.1| (Y11710) collagen type XIV [Homo sapiens] 147 2e-33
emb|CAB71222.1| (AL096771) dJ238D15.1 (collagen, type XII, ... 145 8e-33
pir||A45974 collagen alpha 1(XIV) chain precursor, short fo... 145 8e-33
sp|P13944|CA1C_CHICK COLLAGEN ALPHA 1(XII) CHAIN PRECURSOR ... 145 1e-32
emb|CAB37653.1| (AJ224662) von Willebrand factor [Aplodonti... 143 3e-32
emb|CAB37857.1| (AJ224674) von Willebrand factor [Thryonomy... 143 4e-32
emb|CAB37856.1| (AJ224675) von Willebrand factor [Trichys f... 143 4e-32
emb|CAB86184.1| (AJ238384) von Willebrand factor [Bathyergu... 141 1e-31
gb|AAA30903.1| (L16903) von Willebrand factor [Canis famili... 140 2e-31
emb|CAB86185.1| (AJ238385) von Willebrand Factor [Chinchill... 139 3e-31
emb|CAB37651.1| (AJ224661) von Willebrand factor [Allactaga... 139 4e-31
emb|CAB65984.1| (AL080250) dJ234P15.1 (collagen, type XII, ... 139 6e-31
emb|CAB86203.1| (AJ238386) von Willebrand Factor [Octodon l... 138 8e-31
pdb|1KUN| Solution Structure Of The Human Alpha3-Chain Ty... 138 1e-30
emb|CAB37846.1| (AJ224670) von Willebrand factor [Macropus ... 137 2e-30
pir||PS0323 von Willebrand factor - pig (fragment) >gi|7544... 137 2e-30
emb|CAB37847.1| (AJ224671) von Willebrand factor [Marmota m... 136 3e-30
emb|CAB37670.1| (AJ224668) von Willebrand factor [Myoxus glis] 136 4e-30
gb|AAF25354.1|AF203778_1 (AF203778) von Willebrand factor [... 135 7e-30
emb|CAB37666.1| (AJ224663) von Willebrand factor [Cavia por... 135 7e-30
emb|CAB37665.1| (AJ224664) von Willebrand factor [Coendou m... 135 9e-30
gb|AAB38798.1| (U31607) von Willebrand factor [Dasyprocta l... 135 9e-30
emb|CAB37672.1| (AJ224667) von Willebrand factor [Glaucomys... 134 1e-29
>ref|NP_004360.1| collagen, type VI, alpha 3 [Homo sapiens]
sp|P12111|CA36_HUMAN COLLAGEN ALPHA 3(VI) CHAIN PRECURSOR
pir||CGHU3A collagen alpha 3(VI) chain precursor - human
emb|CAA36267.1| (X52022) collagen type VI, alpha 3 chain [Homo sapiens]
Length = 3176
Score = 3972 bits (10186), Expect = 0.0
Identities = 2045/2176 (93%), Positives = 2045/2176 (93%)
Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE
Sbjct: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120
FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK
Sbjct: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120
Query: 121 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180
GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA
Sbjct: 121 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180
Query: 181 DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240
DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS
Sbjct: 181 DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240
Query: 241 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300
ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS
Sbjct: 241 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300
Query: 301 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360
TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD
Sbjct: 301 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360
Query: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420
EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV
Sbjct: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420
Query: 421 GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480
GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD
Sbjct: 421 GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480
Query: 481 LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540
LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS
Sbjct: 481 LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540
Query: 541 AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600
AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS
Sbjct: 541 AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600
Query: 601 LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660
LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD
Sbjct: 601 LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660
Query: 661 FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXXXXXXXX 720
FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDI
Sbjct: 661 FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDILGHLRQLQLQGGSGLNTG 720
Query: 721 SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780
SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ
Sbjct: 721 SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780
Query: 781 ANKAELEQIAFNPSLVYLMDDFSSXXXXXXXXXXXXTTYVSGGVEEVPLAQPESKRDILF 840
ANKAELEQIAFNPSLVYLMDDFSS TTYVSGGVEEVPLAQPESKRDILF
Sbjct: 781 ANKAELEQIAFNPSLVYLMDDFSSLPALPQQLIQPLTTYVSGGVEEVPLAQPESKRDILF 840
Query: 841 LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL 900
LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL
Sbjct: 841 LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL 900
Query: 901 NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA 960
NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA
Sbjct: 901 NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA 960
Query: 961 SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA 1020
SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA
Sbjct: 961 SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA 1020
Query: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080
PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF
Sbjct: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080
Query: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140
YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT
Sbjct: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140
Query: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 1200
ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV
Sbjct: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 1200
Query: 1201 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD 1260
ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD
Sbjct: 1201 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD 1260
Query: 1261 YLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS 1320
YLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS
Sbjct: 1261 YLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS 1320
Query: 1321 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTIARNADQEELVK 1380
RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTIARNADQEELVK
Sbjct: 1321 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTIARNADQEELVK 1380
Query: 1381 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1440
ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL
Sbjct: 1381 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1440
Query: 1441 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1500
IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL
Sbjct: 1441 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1500
Query: 1501 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1560
DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA
Sbjct: 1501 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1560
Query: 1561 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSXXXX 1620
QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPS
Sbjct: 1561 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSAATP 1620
Query: 1621 XXXXXXXXXXSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL 1680
SRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL
Sbjct: 1621 APPGVDTPPPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL 1680
Query: 1681 VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD 1740
VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD
Sbjct: 1681 VQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLD 1740
Query: 1741 QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG 1800
QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG
Sbjct: 1741 QRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVG 1800
Query: 1801 NXXXXXXXXXXXXXXXHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES 1860
N HDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES
Sbjct: 1801 NVQELSELSEQVLETLHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFES 1860
Query: 1861 KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ 1920
KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ
Sbjct: 1861 KVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQ 1920
Query: 1921 HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV 1980
HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV
Sbjct: 1921 HPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILV 1980
Query: 1981 GLERVVNLERLMHLEFGRGFMXXXXXXXXXXXXXXXXAEQLDNIAEKACCGVPCKCSGQR 2040
GLERVVNLERLMHLEFGRGFM AEQLDNIAEKACCGVPCKCSGQR
Sbjct: 1981 GLERVVNLERLMHLEFGRGFMYDRPLRLNLLDLDYELAEQLDNIAEKACCGVPCKCSGQR 2040
Query: 2041 GDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNGTQGFQGCPGQRGVKGSRGFP 2100
GDR VNGTQGFQGCPGQRGVKGSRGFP
Sbjct: 2041 GDRGPIGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFP 2100
Query: 2101 GEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP 2160
GEK SSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP
Sbjct: 2101 GEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNP 2160
Query: 2161 GQDSQERGPKGETGDL 2176
GQDSQERGPKGETGDL
Sbjct: 2161 GQDSQERGPKGETGDL 2176
Score = 1404 bits (3594), Expect = 0.0
Identities = 712/882 (80%), Positives = 712/882 (80%)
Query: 2295 DDGRDXXXXXXXXXXXXXXXFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
DDGRD FPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ
Sbjct: 2295 DDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
Query: 2355 KXXXXXXXXXXXXXXXXDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVN 2414
K DSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVN
Sbjct: 2355 KGRPGYPGPAGPRGNRGDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVN 2414
Query: 2415 QDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIK 2474
QDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIK
Sbjct: 2415 QDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIK 2474
Query: 2475 NLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLS 2534
NLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLS
Sbjct: 2475 NLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLS 2534
Query: 2535 DAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNID 2594
DAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNID
Sbjct: 2535 DAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNID 2594
Query: 2595 PSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPD 2654
PSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPD
Sbjct: 2595 PSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPD 2654
Query: 2655 PKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA 2714
PKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA
Sbjct: 2655 PKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA 2714
Query: 2715 LGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGI 2774
LGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGI
Sbjct: 2715 LGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGI 2774
Query: 2775 GRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRK 2834
GRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRK
Sbjct: 2775 GRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRK 2834
Query: 2835 QCDWFQGDQPTKNLVKFGHKQXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2894
QCDWFQGDQPTKNLVKFGHKQ
Sbjct: 2835 QCDWFQGDQPTKNLVKFGHKQVNVPNNVTSSPTSNPVTTTKPVTTTKPVTTTTKPVTTTT 2894
Query: 2895 XXXXIINQPSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2954
IINQPS
Sbjct: 2895 KPVTIINQPSVKPAAAKPAPAKPVAAKPVATKTATVRPPVAVKPATAAKPVAAKPAAVRP 2954
Query: 2955 XXXXXXXXXXXXEVPRPQXXXXXXXXXXXXXXVVKMLREVQVFEITENSAKLHWERPEPP 3014
EVPRPQ VVKMLREVQVFEITENSAKLHWERPEPP
Sbjct: 2955 PAAAAKPVATKPEVPRPQAAKPAATKPATTKPVVKMLREVQVFEITENSAKLHWERPEPP 3014
Query: 3015 GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFX 3074
GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSF
Sbjct: 3015 GPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAGQTYHVAVVCYLRSQVRATYHGSFS 3074
Query: 3075 XXXXXXXXXXXXXXXXXXXINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK 3134
INLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK
Sbjct: 3075 TKKSQPPPPQPARSASSSTINLMVSTEPLALTETDICKLPKDEGTCRDFILKWYYDPNTK 3134
Query: 3135 SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3176
SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT
Sbjct: 3135 SCARFWYGGCGGNENKFGSQKECEKVCAPVLAKPGVISVMGT 3176
Score = 77.6 bits (188), Expect = 2e-12
Identities = 95/406 (23%), Positives = 175/406 (42%), Gaps = 57/406 (14%)
Query: 2393 PLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNN 2452
PL P ++ F D S + F +RD + I++ L + P G R+AV Y++
Sbjct: 828 PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 882
Query: 2453 EVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFL 2507
+V E RF + + K +L+ +K +++ T K +L A+ + R F R+ +G L
Sbjct: 883 DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 941
Query: 2508 MRKVAVFFSNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINALQINNTAVGHAL 2566
V + R+S ++ L +G+ P +F + D + + ++ + A
Sbjct: 942 QFLVLL----VAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 997
Query: 2567 VLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDS 2626
LP DL + N+L S + A + D+ F+LD
Sbjct: 998 SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 1036
Query: 2627 AETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVE 2686
+E F +K+++ +V LD+ D RVAVVQ++ + E
Sbjct: 1037 SEGVR-SGFPLLKEFVQRVVESLDVGQDR------VRVAVVQYSDR----------TRPE 1079
Query: 2687 FSLTDYGSKEKLVDFLSRGMTQLQG-TRALGSAIEYTIENVFESAPNPRDLKIVVLMLTG 2745
F L Y +K+ +V+ + R +T L G T G+A+E+ + N+ S+ R + V +L
Sbjct: 1080 FYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 1138
Query: 2746 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
++ ++ + + K G + +GIG +I E+ T + P+
Sbjct: 1139 LTADRSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 1183
Score = 77.6 bits (188), Expect = 2e-12
Identities = 95/406 (23%), Positives = 175/406 (42%), Gaps = 57/406 (14%)
Query: 828 PLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 882
PL P ++ F D S + F +RD + I++ L + P G R+AV Y++
Sbjct: 2393 PLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNN 2452
Query: 883 DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 941
+V E RF + + K +L+ +K +++ T K +L A+ + R F R+ +G L
Sbjct: 2453 EVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFL 2507
Query: 942 QFLVLL----VAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 997
V + R+S ++ L +G+ P +F + D + + ++ + A
Sbjct: 2508 MRKVAVFFSNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINALQINNTAVGHAL 2566
Query: 998 SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 1036
LP DL + N+L S + A + D+ F+LD
Sbjct: 2567 VLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDS 2626
Query: 1037 SEGVR-SGFPLLKEFVQRVVESLDVGQDR------VRVAVVQYSDR----------TRPE 1079
+E F +K+++ +V LD+ D RVAVVQ++ + E
Sbjct: 2627 AETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVE 2686
Query: 1080 FYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 1138
F L Y +K+ +V+ + R +T L G T G+A+E+ + N+ S+ R + V +L
Sbjct: 2687 FSLTDYGSKEKLVDFLSRGMTQLQG-TRALGSAIEYTIENVFESAPNPRDLKIVVLMLTG 2745
Query: 1139 LTADRSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 1183
++ ++ + + K G + +GIG +I E+ T + P+
Sbjct: 2746 EVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
Score = 67.1 bits (161), Expect = 3e-09
Identities = 88/401 (21%), Positives = 174/401 (42%), Gaps = 47/401 (11%)
Query: 1233 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKAEFLLN 1287
++ F +D S+ + F +R ++ +V+ L + RVAV+ ++++ E
Sbjct: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
Query: 1288 AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 1346
K + + ++ L+ +Q ++ A+ +V+RN FKR + V F +
Sbjct: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT- 2520
Query: 1347 KSDDEVVVPAVELKQFGVAPFTIARNADQEELVKISLSPEYV---FSVSTFRELPSLEQK 1403
++ ++ ++L G+ P + R D++ + + ++ V + R+L +
Sbjct: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
Query: 1404 LLTPITTLTSEQIQKLLASTRYPPPAVESDAA------DIVFLIDSSEGVRPDGFAHIRD 1457
+LT L I + P + AA D+ F++DS+E F ++
Sbjct: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
Query: 1458 FVSRIVRRLNIGPSK------VRVGVVQFS------NDVFP----EFYLKTYRSQAPVLD 1501
+++ +VR+L++ P RV VVQ + N P EF L Y S+ ++D
Sbjct: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
Query: 1502 AIRR--LRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRF 1559
+ R +L+G L G A+E+ N+F + R + +VL+L G+ +
Sbjct: 2701 FLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR----DLKIVVLMLTGEVPEQQLEE 2754
Query: 1560 AQVI------RSSGIVSLGVGDRNIDRTELQTITNDPRLVF 1594
AQ + + V LG+G R ++ E+ T ++P VF
Sbjct: 2755 AQRVILQAKCKGYFFVVLGIG-RKVNIKEVYTFASEPNDVF 2794
Score = 67.1 bits (161), Expect = 3e-09
Identities = 88/401 (21%), Positives = 174/401 (42%), Gaps = 47/401 (11%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D S+ + F +R ++ +V+ L + RVAV+ ++++ E
Sbjct: 1233 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKAEFLLN 1287
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPT- 2520
K + + ++ L+ +Q ++ A+ +V+RN FKR + V F +
Sbjct: 1288 AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSG 1346
Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
++ ++ ++L G+ P + R D++ + + ++ V + R+L +
Sbjct: 1347 KSDDEVVVPAVELKQFGVAPFTIARNADQEELVKISLSPEYV---FSVSTFRELPSLEQK 1403
Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
+LT L I + P + AA D+ F++DS+E F ++
Sbjct: 1404 LLTPITTLTSEQIQKLLASTRYPPPAVESDAA------DIVFLIDSSEGVRPDGFAHIRD 1457
Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
+++ +VR+L++ P RV VVQ + N P EF L Y S+ ++D
Sbjct: 1458 FVSRIVRRLNIGPSK------VRVGVVQFS------NDVFP----EFYLKTYRSQAPVLD 1501
Query: 2701 FLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR----DLKIVVLMLTGEVPEQQLEE 2754
+ R +L+G L G A+E+ N+F + R + +VL+L G+ +
Sbjct: 1502 AIRR--LRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRF 1559
Query: 2755 AQRVILQAKCKGYFFVVLGIG-RKVNIKEVYTFASEPNDVF 2794
AQ + + V LG+G R ++ E+ T ++P VF
Sbjct: 1560 AQVI------RSSGIVSLGVGDRNIDRTELQTITNDPRLVF 1594
Score = 63.2 bits (151), Expect = 4e-08
Identities = 36/96 (37%), Positives = 45/96 (46%), Gaps = 7/96 (7%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
G +G +G PGQ G +G +G G + S G +G PG RG
Sbjct: 2207 GAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGARGAPGERGRT 2266
Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
GP G KGE G+ G +G GNP GP+GETGD
Sbjct: 2267 GPLGRKGEPGEPGPKGGIGNP-------GPRGETGD 2295
Score = 58.9 bits (140), Expect = 8e-07
Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 52/370 (14%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D S F + D +++++ L I RV VV +++E T
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 297
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFL---MRKVAVFFSNT 2518
K+ +L +K L A + ++ A+ FV N F R + + +V V S
Sbjct: 298 TYSTKAQVLGAVKALGFA-GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAG 356
Query: 2519 PTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV--LPAGRDLTD 2576
P+ S ++R V+ L A + L Q + ++ + A LV +P R D
Sbjct: 357 PS--SDEIRYGVVALKQASVFSFGL----GAQAASRAELQHIATDDNLVFTVPEFRSFGD 410
Query: 2577 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDI---DMAFILDSAETTTLF 2633
E +L V G + +++ D+ F++D + L
Sbjct: 411 LQEKLLPYIV-----------GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLA 459
Query: 2634 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2693
FN ++ +IA ++++L++ D +VAV Q+A + V+ EF +
Sbjct: 460 NFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT----------VRPEFYFNTHP 503
Query: 2694 SKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL----KIVVLMLTGEVP 2748
+K +++ + R M L G+ GSA+++ N+F S+ R K++VL+ G+
Sbjct: 504 TKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562
Query: 2749 EQQLEEAQRV 2758
++ + AQ +
Sbjct: 563 DEISQPAQEL 572
Score = 58.9 bits (140), Expect = 8e-07
Identities = 81/370 (21%), Positives = 155/370 (41%), Gaps = 52/370 (14%)
Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 297
++ F +D S F + D +++++ L I RV VV +++E T
Sbjct: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
Query: 298 TYSTKAQVLGAVKALGFA-GGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAG 356
K+ +L +K L A + ++ A+ FV N F R + + +V V S
Sbjct: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFL---MRKVAVFFSNT 2518
Query: 357 PS--SDEIRYGVVALKQASVFSFGL----GAQAASRAELQHIATDDNLVFTVPEFRSFGD 410
P+ S ++R V+ L A + L Q + ++ + A LV +P R D
Sbjct: 2519 PTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV--LPAGRDLTD 2576
Query: 411 LQEKLLPYIV-----------GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLA 459
E +L V G + +++ D+ F++D + L
Sbjct: 2577 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDI---DMAFILDSAETTTLF 2633
Query: 460 NFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYADT----------VRPEFYFNTHP 503
FN ++ +IA ++++L++ D +VAV Q+A + V+ EF +
Sbjct: 2634 QFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYG 2693
Query: 504 TKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562
+K +++ + R M L G+ GSA+++ N+F S+ R K++VL+ G+
Sbjct: 2694 SKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPRDL----KIVVLMLTGEVP 2748
Query: 563 DEISQPAQEL 572
++ + AQ +
Sbjct: 2749 EQQLEEAQRV 2758
Score = 55.0 bits (130), Expect = 1e-05
Identities = 77/349 (22%), Positives = 145/349 (41%), Gaps = 42/349 (12%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F LD S V + F +RD V+++VN L I N RV +V +++ TE
Sbjct: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDN----IRVGLVQFSDTPVTEFSLN 694
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKV-AVFFSNTPT 2520
+ KS +L ++ LQ+ S + +A+S+V N F + V + T
Sbjct: 695 TYQTKSDILGHLRQLQLQGGSGLNT-GSALSYVYANHFTEAGGSRIREHVPQLLLLLTAG 753
Query: 2521 RASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
++ +A L+ AGI LT N ++ A +LV +L +
Sbjct: 754 QSEDSYLQAANALTRAGI----LTFCVGASQANKAELEQIAFNPSLV---------YLMD 800
Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
+ L I P + S + A + D+ F+ D + + QF ++
Sbjct: 801 DFSSLPALPQQLIQPLTTYVS--GGVEEVPLAQPESKRDILFLFDGS-ANLVGQFPVVRD 857
Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
++ ++ +L++ P+ R+AV Q++ VKVE ++ SK ++++
Sbjct: 858 FLYKIIDELNVKPEG------TRIAVAQYSDD----------VKVESRFDEHQSKPEILN 901
Query: 2701 FLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR----DLKIVVLMLTG 2745
+ R + LG A++Y +F + R L+ +VL++ G
Sbjct: 902 LVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAG 950
Score = 51.5 bits (121), Expect = 1e-04
Identities = 36/99 (36%), Positives = 42/99 (42%), Gaps = 37/99 (37%)
Query: 2086 GCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGR---RGDKGPR 2142
G G+RG KG RGFPG G KGNPG G GP+
Sbjct: 2302 GSEGRRGKKGERGFPGYP------------------------GPKGNPGEPGLNGTTGPK 2337
Query: 2143 GEKGERGD------VGIRGDPGNPGQDSQERGPKGETGD 2175
G +G RG+ VG +G PG PG GP+G GD
Sbjct: 2338 GIRGRRGNSGPPGIVGQKGRPGYPG----PAGPRGNRGD 2372
Score = 50.4 bits (118), Expect = 3e-04
Identities = 19/40 (47%), Positives = 27/40 (67%)
Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
PG G KG PG+PG G G +G +G G +GPPG++G++
Sbjct: 2206 PGAKGNKGGPGQPGFEGEQGTRGAQGPAGPAGPPGLIGEQ 2245
Score = 46.5 bits (108), Expect = 0.005
Identities = 22/44 (50%), Positives = 28/44 (63%), Gaps = 3/44 (6%)
Query: 2315 FPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
+ GYPG +G PGE PG+NGT G +G G+RG G G G+K
Sbjct: 2060 YRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEK 2103
Score = 43.0 bits (99), Expect = 0.053
Identities = 93/421 (22%), Positives = 158/421 (37%), Gaps = 70/421 (16%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D S + F +RD + ++ L I + +VAV Y + V E F
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLI----QVAVAQYADTVRPEFYFN 500
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFK-----RVRNGFLMRKVAVFFS 2516
K ++ ++ ++ L +A+ FV N F R G V +
Sbjct: 501 THPTKREVITAVRKMK-PLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLI--- 556
Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV-LPA---GR 2572
T ++ ++ + +L + I + + Q ++ A +LV +PA
Sbjct: 557 -TGGKSLDEISQPAQELKRSSIMAFAIGNKGADQA----ELEEIAFDSSLVFIPAEFRAA 611
Query: 2573 DLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTL 2632
L L +L L S P + D+ F+LD +
Sbjct: 612 PLQGMLPGLLAPLRTL------------SGTPEVHSNKR-------DIIFLLDGSANVGK 652
Query: 2633 FQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDY 2692
F ++ ++ LV LD+ D RV +VQ + + PV EFSL Y
Sbjct: 653 TNFPYVRDFVMNLVNSLDIGNDN------IRVGLVQFSDT---------PV-TEFSLNTY 696
Query: 2693 GSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR---DLKIVVLMLTGEV 2747
+K ++ L + QLQG L GSA+ Y N F A R + ++L+LT
Sbjct: 697 QTKSDILGHLRQ--LQLQGGSGLNTGSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQ 754
Query: 2748 PEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEE 2807
E +A + +A G +G + N E+ A P+ V+ L+D + L
Sbjct: 755 SEDSYLQAANALTRA---GILTFCVG-ASQANKAELEQIAFNPSLVY--LMDDFSSLPAL 808
Query: 2808 P 2808
P
Sbjct: 809 P 809
Score = 41.0 bits (94), Expect = 0.20
Identities = 21/39 (53%), Positives = 21/39 (53%)
Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
PG G KGNPG G G G KG RG G G PG GQ
Sbjct: 2124 PGSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQ 2162
Score = 40.6 bits (93), Expect = 0.27
Identities = 19/43 (44%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 2316 PGYPGPKGNPGEPGLN---GTTGPKGIRGRRGNSGPPGIVGQK 2355
PG G G PGE G N G GP G +G +G G PG G++
Sbjct: 2182 PGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPGFEGEQ 2224
Score = 40.2 bits (92), Expect = 0.35
Identities = 29/96 (30%), Positives = 37/96 (38%), Gaps = 25/96 (26%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
G G G PG+ GV G G G+ G +G PG +G+K
Sbjct: 2174 GDLGPMGVPGRDGVPGGPGETGKNGGF---------------------GRRGPPGAKGNK 2212
Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
G G+ G G+ G RG G G GP G G+
Sbjct: 2213 GGPGQPGFEGEQGTRGAQGPAG----PAGPPGLIGE 2244
Score = 39.5 bits (90), Expect = 0.60
Identities = 21/51 (41%), Positives = 28/51 (54%), Gaps = 12/51 (23%)
Query: 2317 GYPGPKGNPGEPGLN------------GTTGPKGIRGRRGNSGPPGIVGQK 2355
G+PG KG GE GL+ G++G KG GRRG+ GP G G++
Sbjct: 2098 GFPGEKGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKGER 2148
Score = 37.9 bits (86), Expect = 1.8
Identities = 18/40 (45%), Positives = 22/40 (55%)
Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
PG G +G PG+ G G GP G+ G +G G PG G K
Sbjct: 2055 PGEDGYRGYPGDEGGPGERGPPGVNGTQGFQGCPGQRGVK 2094
Score = 37.5 bits (85), Expect = 2.3
Identities = 17/40 (42%), Positives = 22/40 (54%)
Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
PG+ G +G G G G GP G+ G +G SGP G G +
Sbjct: 2218 PGFEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAR 2257
Score = 36.7 bits (83), Expect = 4.0
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 2317 GYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVG 2353
G GP+G+ G PG G TGP G +G G GP G +G
Sbjct: 2246 GISGPRGSGGARGAPGERGRTGPLGRKGEPGEPGPKGGIG 2285
Score = 36.4 bits (82), Expect = 5.2
Identities = 19/37 (51%), Positives = 21/37 (56%), Gaps = 3/37 (8%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353
G GPKG PGE G G G +G G R GPPG+ G
Sbjct: 2047 GSIGPKGIPGEDGYRGYPGDEGGPGER---GPPGVNG 2080
Score = 36.4 bits (82), Expect = 5.2
Identities = 17/36 (47%), Positives = 18/36 (49%)
Query: 2320 GPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
GP G PG G+ G G G G G GPPG G K
Sbjct: 2177 GPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNK 2212
>gb|AAD01978.1| (AF034136) collagen alpha3(VI) [Mus musculus]
Length = 1703
Score = 2721 bits (6976), Expect = 0.0
Identities = 1379/1706 (80%), Positives = 1529/1706 (88%), Gaps = 3/1706 (0%)
Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
MRKHRHLPLVAVF L SG T AQQ DVKNGAAADI+FLVDSSW+ G++ F LV+E
Sbjct: 1 MRKHRHLPLVAVFSLLFSGIAMTRAQQH-GDVKNGAAADIVFLVDSSWSAGKDRFLLVQE 59
Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120
FL DVV+SLAVG+NDFHFALV+ NGNPHTEFLLNTY +KQEVLSHI+NMSYIGG+NQTGK
Sbjct: 60 FLSDVVESLAVGDNDFHFALVRLNGNPHTEFLLNTYHSKQEVLSHIANMSYIGGSNQTGK 119
Query: 121 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180
GLEY++ SHLT+A+GSRA DGVPQVIVVLTDG S+DG ALPSAELKSADVNVFA+GVE A
Sbjct: 120 GLEYVIHSHLTEASGSRAADGVPQVIVVLTDGQSEDGFALPSAELKSADVNVFAVGVEGA 179
Query: 181 DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240
DE AL E+ASEPL+MH+FNLEN TSLH +VGNLVSC+HSSV+PERAGD E+LKDITAQDS
Sbjct: 180 DERALGEVASEPLSMHVFNLENVTSLHGLVGNLVSCIHSSVNPERAGDKESLKDITAQDS 239
Query: 241 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300
ADIIFLIDGS NTG+ NF VI DFLVN+LE+L +G QQ++VGVVQ+S+EP TMFSL++Y
Sbjct: 240 ADIIFLIDGSQNTGNANFDVIRDFLVNVLERLSVGNQQVQVGVVQYSEEPITMFSLNSYP 299
Query: 301 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360
+KA VL AVK L GGE ANIG ALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD
Sbjct: 300 SKAAVLDAVKGLSLVGGESANIGQALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 359
Query: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420
EIR VVALKQASVFSFGLGAQAASRAELQHIATDD+LVFTVPEFRSFGDLQE++LPY+V
Sbjct: 360 EIRDSVVALKQASVFSFGLGAQAASRAELQHIATDDSLVFTVPEFRSFGDLQEQILPYLV 419
Query: 421 GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480
GVAQRHIVL+PP IVTQV+EVNKRDIVFLVDGSS+LG +NFNAIRDF+ +VIQRLEIGQD
Sbjct: 420 GVAQRHIVLQPPAIVTQVMEVNKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQD 479
Query: 481 LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540
L+QV+VAQYADTV+PEFY N++ KR+ +TAVRKM+ L+GSALYTGS+LDFVRNNLFTSS
Sbjct: 480 LVQVSVAQYADTVKPEFYLNSYTNKRDAVTAVRKMRALNGSALYTGSSLDFVRNNLFTSS 539
Query: 541 AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600
AG+RAAEG+PKLLVLITGGKSLDE+SQPAQELKR SIMA A+G+K AD+ EL+EIAFDSS
Sbjct: 540 AGHRAAEGVPKLLVLITGGKSLDEVSQPAQELKRGSIMALAVGSKAADEDELKEIAFDSS 599
Query: 601 LVFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRD 660
LVFIPAEFR APLQ MLP L+APLRTL+GT EVH NKRDIIFLLDGS NVGK NFPYVRD
Sbjct: 600 LVFIPAEFRPAPLQNMLPSLMAPLRTLTGTTEVHVNKRDIIFLLDGSDNVGKNNFPYVRD 659
Query: 661 FVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXXXXXXXX 720
FV NLVNSLD+G+DNIRVGLVQFSDTPVTEFSL+TYQTKS++
Sbjct: 660 FVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTYQTKSELLAHLRRLQLKGGSGLNAG 719
Query: 721 SALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQ 780
SALSY++ANHFTEAGGSR REHVPQLLLLL AG SED+YLQAANAL R+G+LTFCVG ++
Sbjct: 720 SALSYIHANHFTEAGGSRTREHVPQLLLLLMAGPSEDAYLQAANALVRSGVLTFCVGTNR 779
Query: 781 ANKAELEQIAFNPSLVYLMDDFSSXXXXXXXXXXXXTTYVSGGVEEVPLAQPESKRDILF 840
A+KAELE IAFNPSLVYLMDDF S TTYVSGGV+EVPL+QPESKRDILF
Sbjct: 780 ADKAELEHIAFNPSLVYLMDDFRSLPSLPQQLIQPLTTYVSGGVQEVPLSQPESKRDILF 839
Query: 841 LFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEIL 900
LFDGS N++GQFP VRDFLY+II+EL+VKP+GTR+A+AQ+SDDV++ESRF EHQ+K EIL
Sbjct: 840 LFDGSVNVLGQFPAVRDFLYRIIEELDVKPDGTRVAIAQFSDDVRLESRFSEHQTKAEIL 899
Query: 901 NLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPA 960
NLVK+MK+KTGKALNLGYALDYA R IFV+SAGSRIED V QFLVLLVAGRSSD V GPA
Sbjct: 900 NLVKKMKLKTGKALNLGYALDYALRNIFVRSAGSRIEDNVQQFLVLLVAGRSSDAVAGPA 959
Query: 961 SNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKSVHNGA 1020
S+LKQ GVVPFIFQAKNA+P+ELEQIVLSPAFILAAESLPKIGDL QIV+LLK+
Sbjct: 960 SSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILAAESLPKIGDLQSQIVSLLKAEQGS- 1018
Query: 1021 PAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080
PVSGEKDVVFL+DGSEGVRSGFPLLK+FVQRVVESLDVG DRVRVA+VQYSDRTRPEF
Sbjct: 1019 -GPVSGEKDVVFLIDGSEGVRSGFPLLKDFVQRVVESLDVGPDRVRVALVQYSDRTRPEF 1077
Query: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140
YLNS+M++Q V++A+R+LTLLGGPTPNTGAALEFVLRNIL SS GSRI EGVPQLLIVLT
Sbjct: 1078 YLNSHMDQQGVISAIRRLTLLGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVLT 1137
Query: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQV 1200
A+ SGDDVR PSVV+K+GGAVPIGIGIGNADI+EMQTISFIPDFAVAIPTFR+LGT+QQV
Sbjct: 1138 AEPSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDFAVAIPTFRELGTIQQV 1197
Query: 1201 ISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVRTLIERLVD 1260
ISERV QL REELS L+P+L P GVG K+DVVFLIDGS++AGPEFQY+RTLIER+V+
Sbjct: 1198 ISERVIQLNREELSSLKPILTPSTGAGVGSKKDVVFLIDGSRNAGPEFQYIRTLIERIVE 1257
Query: 1261 YLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVS 1320
YLD+GFDTTRVAVIQFS+D K EF LNAH SKDEVQNAV+RLRPKGG Q+ +GNALEYV
Sbjct: 1258 YLDIGFDTTRVAVIQFSEDSKMEFPLNAHFSKDEVQNAVRRLRPKGGSQVYIGNALEYVL 1317
Query: 1321 RNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTIARNADQEELVK 1380
+NIF+RPLGSRIEEGVPQFLVLISSGKSDDEV AVELKQFGVAP TIAR+ DQEELVK
Sbjct: 1318 KNIFQRPLGSRIEEGVPQFLVLISSGKSDDEVDDSAVELKQFGVAPLTIARHTDQEELVK 1377
Query: 1381 ISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFL 1440
ISLSPEYV+SVSTFRELP LEQKLL PITTLTS+QI ++LASTRYPP VESDAADIVFL
Sbjct: 1378 ISLSPEYVYSVSTFRELPRLEQKLLKPITTLTSQQIHQILASTRYPPSVVESDAADIVFL 1437
Query: 1441 IDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVL 1500
IDSS+ V+PDG AHIRDFVSRIVRRLNIGPSKVR+GVVQFSNDVFPEFYLKT++SQ+ VL
Sbjct: 1438 IDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGVVQFSNDVFPEFYLKTHKSQSSVL 1497
Query: 1501 DAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFA 1560
+AIRRLR +GGSPLNTG+ALEFVARNLFVKSAGSRIEDGVPQHLVL LGGKSQDDV+R A
Sbjct: 1498 EAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQDDVARHA 1557
Query: 1561 QVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNSFGPSXXXX 1620
QVI SSGIVSLG+GDRNIDRT+LQTITNDPRLVFTVREFRELPNIEER+M SFGPS
Sbjct: 1558 QVISSSGIVSLGIGDRNIDRTDLQTITNDPRLVFTVREFRELPNIEERVMLSFGPSGATP 1617
Query: 1621 XXXXXXXXXXSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGL 1680
SRPEKKKADIVFLLDGSINFRRDSFQEVLRF SEIVDTVYEDGDSI+VGL
Sbjct: 1618 QPPGVDLPSPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFASEIVDTVYEDGDSIRVGL 1677
Query: 1681 VQYNSDPTDEFFLKDFSTKRQIIDAI 1706
VQYNSDPTDEFFL+DFSTKRQIIDAI
Sbjct: 1678 VQYNSDPTDEFFLRDFSTKRQIIDAI 1703
Score = 946 bits (2419), Expect = 0.0
Identities = 575/1593 (36%), Positives = 867/1593 (54%), Gaps = 56/1593 (3%)
Query: 234 DITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTM 293
D+ +ADI+FL+D S + G F ++ +FL +++E L +G +V+ + P T
Sbjct: 30 DVKNGAAADIVFLVDSSWSAGKDRFLLVQEFLSDVVESLAVGDNDFHFALVRLNGNPHTE 89
Query: 294 FSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLI 353
F L+TY +K +VL + + + GG G L++V+ +H T A GSR +GVPQV+V++
Sbjct: 90 FLLNTYHSKQEVLSHIANMSYIGGS-NQTGKGLEYVIHSHLTEASGSRAADGVPQVIVVL 148
Query: 354 SAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDL 411
+ G S D LK A V F +G + A L +A++ VF + S L
Sbjct: 149 TDGQSEDGFALPSAELKSADVNVFAVGVEGADERALGEVASEPLSMHVFNLENVTSLHGL 208
Query: 412 QEKLLPYIVGVAQRHIVLKPPTI-----VTQVIEVNKRDIVFLVDGSSALGLANFNAIRD 466
L+ I H + P + + + DI+FL+DGS G ANF+ IRD
Sbjct: 209 VGNLVSCI------HSSVNPERAGDKESLKDITAQDSADIIFLIDGSQNTGNANFDVIRD 262
Query: 467 FIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTG 526
F+ V++RL +G +QV V QY++ F N++P+K V+ AV+ + + G + G
Sbjct: 263 FLVNVLERLSVGNQQVQVGVVQYSEEPITMFSLNSYPSKAAVLDAVKGLSLVGGESANIG 322
Query: 527 SALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKG 586
ALDFV N FT + G R EG+P++LVLI+ G S DEI LK++S+ +F +G +
Sbjct: 323 QALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRDSVVALKQASVFSFGLGAQA 382
Query: 587 ADQAELEEIAFDSSLVFIPAEFRA-APLQG-MLPGL---------LAPLRTLSGTPEVHS 635
A +AEL+ IA D SLVF EFR+ LQ +LP L L P ++ EV
Sbjct: 383 ASRAELQHIATDDSLVFTVPEFRSFGDLQEQILPYLVGVAQRHIVLQPPAIVTQVMEV-- 440
Query: 636 NKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNT 695
NKRDI+FL+DGS+++G +NF +RDFV ++ L+IG D ++V + Q++DT EF LN+
Sbjct: 441 NKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVKPEFYLNS 500
Query: 696 YQTKSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQS 755
Y K D S+L +V N FT + G R E VP+LL+L+T G+S
Sbjct: 501 YTNKRDAVTAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKS 560
Query: 756 EDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSXXXXXXXXXXX 815
D Q A L R I+ VG+ A++ EL++IAF+ SLV++ +F
Sbjct: 561 LDEVSQPAQELKRGSIMALAVGSKAADEDELKEIAFDSSLVFIPAEFRPAPLQNMLPSLM 620
Query: 816 XTTYVSGGVEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTR 874
G EV + +KRDI+FL DGS N+ FP VRDF+ +++ L+V + R
Sbjct: 621 APLRTLTGTTEVHV----NKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIR 676
Query: 875 IAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGS 934
+ + Q+SD E D +Q+K E+L ++R+++K G LN G AL Y F ++ GS
Sbjct: 677 VGLVQFSDTPVTEFSLDTYQTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGS 736
Query: 935 RIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFIL 994
R + V Q L+LL+AG S D A+ L +SGV+ F AD AELE I +P+ +
Sbjct: 737 RTREHVPQLLLLLMAGPSEDAYLQAANALVRSGVLTFCVGTNRADKAELEHIAFNPSLVY 796
Query: 995 AAESLPKIGDLHPQIVNLLKSVHNGAPAPV-----SGEKDVVFLLDGSEGVRSGFPLLKE 1049
+ + L Q++ L + +G V ++D++FL DGS V FP +++
Sbjct: 797 LMDDFRSLPSLPQQLIQPLTTYVSGGVQEVPLSQPESKRDILFLFDGSVNVLGQFPAVRD 856
Query: 1050 FVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTG 1109
F+ R++E LDV D RVA+ Q+SD R E + + K +++N V+++ L G N G
Sbjct: 857 FLYRIIEELDVKPDGTRVAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLG 916
Query: 1110 AALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGN 1169
AL++ LRNI V SAGSRI + V Q L++L A RS D V P+ +K+ G VP N
Sbjct: 917 YALDYALRNIFVRSAGSRIEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKN 976
Query: 1170 ADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVG 1229
A+ +E++ I P F +A + ++G +Q S+ V+ L E+ S V
Sbjct: 977 ANPSELEQIVLSPAFILAAESLPKIGDLQ---SQIVSLLKAEQ-----------GSGPVS 1022
Query: 1230 GKRDVVFLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAH 1289
G++DVVFLIDGS+ F ++ ++R+V+ LDVG D RVA++Q+SD + EF LN+H
Sbjct: 1023 GEKDVVFLIDGSEGVRSGFPLLKDFVQRVVESLDVGPDRVRVALVQYSDRTRPEFYLNSH 1082
Query: 1290 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 1349
+ V +A++RL GG N G ALE+V RNI GSRI EGVPQ L+++++ S
Sbjct: 1083 MDQQGVISAIRRLTLLGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVLTAEPSG 1142
Query: 1350 DEVVVPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPI 1408
D+V P+V LKQ G P I NAD E+ IS P++ ++ TFREL +++Q + +
Sbjct: 1143 DDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIPDFAVAIPTFRELGTIQQVISERV 1202
Query: 1409 TTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI 1468
L E++ L A D+VFLID S P+ F +IR + RIV L+I
Sbjct: 1203 IQLNREELSSLKPILTPSTGAGVGSKKDVVFLIDGSRNAGPE-FQYIRTLIERIVEYLDI 1261
Query: 1469 GPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLF 1528
G RV V+QFS D EF L + S+ V +A+RRLR +GGS + G ALE+V +N+F
Sbjct: 1262 GFDTTRVAVIQFSEDSKMEFPLNAHFSKDEVQNAVRRLRPKGGSQVYIGNALEYVLKNIF 1321
Query: 1529 VKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITN 1588
+ GSRIE+GVPQ LVL+ GKS D+V A ++ G+ L + R+ D+ EL I+
Sbjct: 1322 QRPLGSRIEEGVPQFLVLISSGKSDDEVDDSAVELKQFGVAPLTIA-RHTDQEELVKISL 1380
Query: 1589 DPRLVFTVREFRELPNIEERIMNSFGP--SXXXXXXXXXXXXXXSRPEKKKADIVFLLDG 1646
P V++V FRELP +E++++ S S E ADIVFL+D
Sbjct: 1381 SPEYVYSVSTFRELPRLEQKLLKPITTLTSQQIHQILASTRYPPSVVESDAADIVFLIDS 1440
Query: 1647 SINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAI 1706
S + D + FVS IV + +++G+VQ+++D EF+LK ++ +++AI
Sbjct: 1441 SDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGVVQFSNDVFPEFYLKTHKSQSSVLEAI 1500
Query: 1707 NKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLAL 1766
++ +KGG NT LE + N FV AGSR++ VPQ + GGKS +D + +
Sbjct: 1501 RRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQDDVARHAQVI 1560
Query: 1767 TQRGVKVFAVGVRNIDSEEVGKIASNSATAFRV 1799
+ G+ +G RNID ++ I ++ F V
Sbjct: 1561 SSSGIVSLGIGDRNIDRTDLQTITNDPRLVFTV 1593
Score = 71.0 bits (171), Expect = 2e-10
Identities = 88/402 (21%), Positives = 169/402 (41%), Gaps = 51/402 (12%)
Query: 2393 PLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNN 2452
PL P ++ F D S V F +RD + I+ L + P G RVA+ +++
Sbjct: 827 PLSQPESKRDILFLFDGSVNV-LGQFPAVRDFLYRIIEELDVK----PDGTRVAIAQFSD 881
Query: 2453 EVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVA 2512
+V E RF++ + K+ +L+ +K +++ T K +L A+ + RN F R + V
Sbjct: 882 DVRLESRFSEHQTKAEILNLVKKMKLK-TGKALNLGYALDYALRNIFVRSAGSRIEDNVQ 940
Query: 2513 VFF-SNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINALQINNTAVGHALVLPA 2570
F R+S + L G+ P +F + + + + ++ + A LP
Sbjct: 941 QFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILAAESLPK 1000
Query: 2571 GRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETT 2630
DL + ++L ++ + + D+ F++D +E
Sbjct: 1001 IGDLQSQIVSLLKA-----------------------EQGSGPVSGEKDVVFLIDGSEGV 1037
Query: 2631 TLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLT 2690
F +K ++ +V LD+ PD RVA+VQ++ + EF L
Sbjct: 1038 R-SGFPLLKDFVQRVVESLDVGPDR------VRVALVQYSDR----------TRPEFYLN 1080
Query: 2691 DYGSKEKLVDFLSRGMTQLQG-TRALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPE 2749
+ ++ ++ + R +T L G T G+A+E+ + N+ S+ R + V +L E
Sbjct: 1081 SHMDQQGVISAIRR-LTLLGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVLTAE 1139
Query: 2750 QQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
++ + + K G + +GIG +I E+ T + P+
Sbjct: 1140 PSGDDVRGPSVVLKQGGAVPIGIGIG-NADISEMQTISFIPD 1180
Score = 57.0 bits (135), Expect = 3e-06
Identities = 76/351 (21%), Positives = 145/351 (40%), Gaps = 52/351 (14%)
Query: 2392 GPLECPVFPTELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYN 2451
G E V ++ F LD S+ V ++ F +RD V ++VN L + N RV +V ++
Sbjct: 628 GTTEVHVNKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDN----IRVGLVQFS 683
Query: 2452 NEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKV 2511
+ TE + KS LL ++ LQ+ S + +A+S++ N F V
Sbjct: 684 DTPVTEFSLDTYQTKSELLAHLRRLQLKGGSGLNA-GSALSYIHANHFTEAGGSRTREHV 742
Query: 2512 AVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALV---- 2567
A P +A L+ ++A + LT + ++ + A +LV
Sbjct: 743 PQLL--LLLMAGPS-EDAYLQAANALVRSGVLTFCVGTNRADKAELEHIAFNPSLVYLMD 799
Query: 2568 ----LPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFI 2623
LP+ L L LT +V + + S +P + D+ F+
Sbjct: 800 DFRSLPS---LPQQLIQPLTTYVSGGVQEVPLS------QPESKR----------DILFL 840
Query: 2624 LDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPV 2683
D + L QF ++ ++ ++ +LD+ PD RVA+ Q + V
Sbjct: 841 FDGS-VNVLGQFPAVRDFLYRIIEELDVKPDG------TRVAIAQFSDD----------V 883
Query: 2684 KVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR 2734
++E +++ +K ++++ + + + LG A++Y + N+F + R
Sbjct: 884 RLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSAGSR 934
Score = 55.0 bits (130), Expect = 1e-05
Identities = 84/402 (20%), Positives = 162/402 (39%), Gaps = 50/402 (12%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D SEGV F ++D V +V L + P RVA+V Y++ E
Sbjct: 1026 DVVFLIDGSEGVRSG-FPLLKDFVQRVVESLDVG----PDRVRVALVQYSDRTRPEFYLN 1080
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARN-----TFKRVRNGFLMRKVAVFFS 2516
+ ++ I+ L + L + A+ FV RN T R+ G + +
Sbjct: 1081 SHMDQQGVISAIRRLTL-LGGPTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVL--- 1136
Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTD 2576
T + +R + L G P+ + I+ +Q + A+ +P R+L
Sbjct: 1137 -TAEPSGDDVRGPSVVLKQGGAVPIGIGIGNAD--ISEMQTISFIPDFAVAIPTFRELGT 1193
Query: 2577 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFN 2636
+ + + L+ + S +P AG D+ F++D + +F
Sbjct: 1194 IQQVISERVIQLNREELS------SLKPILTPSTGAGVGSKKDVVFLIDGSRNAGP-EFQ 1246
Query: 2637 EMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKE 2696
++ I +V LD+ D RVAV+Q + K+EF L + SK+
Sbjct: 1247 YIRTLIERIVEYLDIGFDT------TRVAVIQFSEDS----------KMEFPLNAHFSKD 1290
Query: 2697 KLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR----DLKIVVLMLTGEVPEQQL 2752
++ + + R + +G+A+EY ++N+F+ R + +VL+ +G+ ++
Sbjct: 1291 EVQNAVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKSDDEVD 1350
Query: 2753 EEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVF 2794
+ A + K + L I R + +E+ + P V+
Sbjct: 1351 DSA------VELKQFGVAPLTIARHTDQEELVKISLSPEYVY 1386
Score = 53.5 bits (126), Expect = 4e-05
Identities = 72/305 (23%), Positives = 129/305 (41%), Gaps = 42/305 (13%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D+S+ V D +RD V IV L I P+ R+ VV ++N+V E
Sbjct: 1433 DIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIG----PSKVRIGVVQFSNDVFPEFYLK 1488
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFLMRKVAVFFS 2516
K +S +L+ I+ L+ S + A+ FVARN F R+ +G + + + +F
Sbjct: 1489 THKSQSSVLEAIRRLRFKGGSPLNT-GRALEFVARNLFVKSAGSRIEDG-VPQHLVLFLG 1546
Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFL-TRQEDRQLINALQINNTAVGHALVLPAGRDLT 2575
++ + +S +GI L + R DR + + + V + R+L
Sbjct: 1547 G---KSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLV---FTVREFRELP 1600
Query: 2576 DFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQF 2635
+ E V+ P S PS +++ A D+ F+LD + F
Sbjct: 1601 NIEERVMLSFGPSGATPQPPGVDLPS--PSRPEKKKA------DIVFLLDGSINFRRDSF 1652
Query: 2636 NEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSK 2695
E+ ++ + +V + D RV +VQ+ S+ D EF L D+ +K
Sbjct: 1653 QEVLRFASEIVDTVYEDGDS------IRVGLVQY-NSDPTD---------EFFLRDFSTK 1696
Query: 2696 EKLVD 2700
+++D
Sbjct: 1697 RQIID 1701
Score = 50.8 bits (119), Expect = 2e-04
Identities = 73/341 (21%), Positives = 144/341 (41%), Gaps = 46/341 (13%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D+S +D F +++ + +V L + +++ A+V N TE
Sbjct: 38 DIVFLVDSSWSAGKDRFLLVQEFLSDVVESLAVGDND----FHFALVRLNGNPHTEFLLN 93
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQ--QSLETAM-SFVARNTFKRVRNGFLMRKVAVFFSNT 2518
K +L I N+ S Q + LE + S + + R +G + +V V ++
Sbjct: 94 TYHSKQEVLSHIANMSYIGGSNQTGKGLEYVIHSHLTEASGSRAADG--VPQVIVVLTDG 151
Query: 2519 PTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFL 2578
+ L A LK +D + + + ++R A+G P + + L
Sbjct: 152 QSEDGFALPSAELKSADVNVFAVGVEGADER-----------ALGEVASEPLSMHVFN-L 199
Query: 2579 ENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDV----DIDMAFILDSAETTTLFQ 2634
ENV + H + SC S P + + D+ D+ F++D ++ T
Sbjct: 200 ENVTSLH---GLVGNLVSCIHSSVNPERAGDKESLKDITAQDSADIIFLIDGSQNTGNAN 256
Query: 2635 FNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGS 2694
F+ ++ ++ ++ +L + +V VVQ+ S P+ + FSL Y S
Sbjct: 257 FDVIRDFLVNVLERLSV------GNQQVQVGVVQY---------SEEPITM-FSLNSYPS 300
Query: 2695 KEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPR 2734
K ++D + +G++ + G A +G A+++ +EN F A R
Sbjct: 301 KAAVLDAV-KGLSLVGGESANIGQALDFVVENHFTRAGGSR 340
Score = 43.4 bits (100), Expect = 0.040
Identities = 41/147 (27%), Positives = 68/147 (45%), Gaps = 24/147 (16%)
Query: 2619 DMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNA 2678
D+ F+LD ++ F ++ ++ LV LD+ D RV +VQ + +
Sbjct: 638 DIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDN------IRVGLVQFSDT------ 685
Query: 2679 SMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPRDL 2736
PV EFSL Y +K +L+ L R QL+G L GSA+ Y N F A R
Sbjct: 686 ---PV-TEFSLDTYQTKSELLAHLRR--LQLKGGSGLNAGSALSYIHANHFTEAGGSRTR 739
Query: 2737 ----KIVVLMLTGEVPEQQLEEAQRVI 2759
++++L++ G + L+ A ++
Sbjct: 740 EHVPQLLLLLMAGPSEDAYLQAANALV 766
>sp|P15989|CA36_CHICK COLLAGEN ALPHA 3(VI) CHAIN PRECURSOR
pir||A37797 collagen alpha 3(VI) chain precursor - chicken
gb|AAA03201.1| (M24282) alpha-3 collagen type VI [Gallus gallus]
Length = 3137
Score = 2606 bits (6681), Expect = 0.0
Identities = 1332/2188 (60%), Positives = 1650/2188 (74%), Gaps = 19/2188 (0%)
Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
MRKHRHLPL A+ L LSGF + AQQQ A V+N A ADIIFLVDSSW+IG+EHFQLVRE
Sbjct: 1 MRKHRHLPLAAILGLLLSGFCSVGAQQQAA-VRNVAVADIIFLVDSSWSIGKEHFQLVRE 59
Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTNQTGK 120
FLYDVVK+L VG NDF FALVQF+GNPHTEF LNTY + Q+VLSHI+NM Y+GG ++TGK
Sbjct: 60 FLYDVVKALDVGGNDFRFALVQFSGNPHTEFQLNTYPSNQDVLSHIANMPYMGGGSKTGK 119
Query: 121 GLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDA 180
GLEY++++HLTKAAGSRA +GVPQVI+VLTDG S+D +ALPS+ LKSA VN+ A+GV+DA
Sbjct: 120 GLEYLIENHLTKAAGSRASEGVPQVIIVLTDGQSQDDVALPSSVLKSAHVNMIAVGVQDA 179
Query: 181 DEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQDS 240
EG LKEIAS P + H+FNLENFT+LH IVG+LV+ V +S++PE+AG +KDITAQ+S
Sbjct: 180 VEGELKEIASRPFDTHLFNLENFTALHGIVGDLVASVRTSMTPEQAGAKGLVKDITAQES 239
Query: 241 ADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYS 300
AD+IFLIDGS+N GSVNF I DFLVNL+E L +G QQI +GVVQ+SD+PRT F+L++YS
Sbjct: 240 ADLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIGVVQYSDQPRTEFALNSYS 299
Query: 301 TKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSD 360
TKA VL AVKAL F GG+ AN G AL++VVEN FT+AGGSR+EE VPQ+LVLIS G SSD
Sbjct: 300 TKADVLDAVKALSFRGGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGGESSD 359
Query: 361 EIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIV 420
+IR G++A+KQAS+FSF +G A AELQ IATD + FT + R+ L+E LLP IV
Sbjct: 360 DIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLLPNIV 419
Query: 421 GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQD 480
GVAQR I+L+ PTIVT+VIEVNK+DIVFL+DGS+ALG FN+IRDF+AK++QRLE+G D
Sbjct: 420 GVAQRLILLEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVGPD 479
Query: 481 LIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSS 540
LIQVAVAQYADTVRPEFYFNTH +++V+ V+KMK + G+AL TGSALDFVRNN FTS+
Sbjct: 480 LIQVAVAQYADTVRPEFYFNTHQNRKDVMANVKKMKLMGGTALNTGSALDFVRNNFFTSA 539
Query: 541 AGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSS 600
AG R EG+ +LVLITGGKS+D + Q A E+KR+ I+ A+G++ AD AEL+EIA +
Sbjct: 540 AGCRMEEGVLPMLVLITGGKSMDAVEQAAAEMKRNRIVILAVGSRNADVAELQEIAHERD 599
Query: 601 LVFIPAEFRAAPLQGMLPGLLAPLRTLSG------TPEVHSNKRDIIFLLDGSANVGKTN 654
VF P +FR +Q +LP +L+P+RTLSG TP V KRDIIFLLDGS NVG N
Sbjct: 600 FVFQPNDFRLQFMQAILPEVLSPIRTLSGGMVIHETPSVQVTKRDIIFLLDGSLNVGNAN 659
Query: 655 FPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXX 714
FP+VRDFV+ LVN LD+G D IRVGLVQFSDTP TEFSL +YQTKSDI
Sbjct: 660 FPFVRDFVVTLVNYLDVGTDKIRVGLVQFSDTPKTEFSLYSYQTKSDIIQRLGQLRPKGG 719
Query: 715 XXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTF 774
SAL++V +NHFTEAGGSRI E VPQ+L+L+TAG+S +LQ +N L RAG+LTF
Sbjct: 720 SVLNTGSALNFVLSNHFTEAGGSRINEQVPQVLVLVTAGRSAVPFLQVSNDLARAGVLTF 779
Query: 775 CVGASQANKAELEQIAFNPSLVYLMDDFSSXXXXXXXXXXXXTTYVSGGVEEVPLAQPES 834
VG A+KAELEQIAFNP +VY MDDFS TT VSGGVEEVPLA ES
Sbjct: 780 AVGVRNADKAELEQIAFNPKMVYFMDDFSDLTTLPQELKKPITTIVSGGVEEVPLAPTES 839
Query: 835 KRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ 894
K+DILFL DGSANL+G FP VRDF++K+I +LNV P+ TR+AVAQ+SD++++E F E
Sbjct: 840 KKDILFLIDGSANLLGSFPAVRDFIHKVISDLNVGPDATRVAVAQFSDNIQIEFDFAELP 899
Query: 895 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSD 954
SK ++L VKRM++KTGK LN+G ALD R +FVK AGSRIE+G+ QFLVLL AGRS+D
Sbjct: 900 SKQDMLLKVKRMRLKTGKQLNIGVALDEVMRRLFVKEAGSRIEEGIPQFLVLLAAGRSTD 959
Query: 955 RVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLK 1014
V+ P+ LK++GVV F +AKNAD +ELE+I +P FIL ESLP+I +L IVNLLK
Sbjct: 960 EVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNVESLPRISELQANIVNLLK 1019
Query: 1015 SVHNGAPAPVSGE-KDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYS 1073
++ GE KDVVFL+DGS+GVR GFPLLK FV+RVVESLD+G+D+VRVA+VQYS
Sbjct: 1020 TIQFQPTVVERGEKKDVVFLIDGSDGVRRGFPLLKTFVERVVESLDIGRDKVRVAIVQYS 1079
Query: 1074 DRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVP 1133
+ +PEF L++Y +K D+V+A++ LT++GG NTGAAL+++++N+ S+GSRI EGVP
Sbjct: 1080 NAIQPEFLLDAYEDKADLVSAIQALTIMGGSPLNTGAALDYLIKNVFTVSSGSRIAEGVP 1139
Query: 1134 QLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQ 1193
Q LI+LTADRS DDVR PSVV+K G VP GIGIGNAD+TE+QTISF+PDFA+++P F Q
Sbjct: 1140 QFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIGNADLTELQTISFLPDFAISVPDFSQ 1199
Query: 1194 LGTVQQVISERVTQLTREELSRLQP-VLQPLPSPGVGGKRDVVFLIDGSQSAGPEFQYVR 1252
L +VQQ +S RV +LT++E+ L P ++ PSP VG KRDVVFL+DGS+ A EF +R
Sbjct: 1200 LDSVQQAVSNRVIRLTKKEIESLAPDLVFTSPSP-VGVKRDVVFLVDGSRYAAQEFYLIR 1258
Query: 1253 TLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINV 1312
LIER+V+ LDVGFDTTR++V+QFS+ P EFLLNAHS+KDEVQ AV+RLRP+GG+Q+NV
Sbjct: 1259 DLIERIVNNLDVGFDTTRISVVQFSEHPHVEFLLNAHSTKDEVQGAVRRLRPRGGQQVNV 1318
Query: 1313 GNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTIARN 1372
G ALE+V++ IF RP GSRIEEGVPQFLV++SS KSDD++ P+V++KQ GVAP IA+N
Sbjct: 1319 GEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSRKSDDDLEFPSVQVKQVGVAPMVIAKN 1378
Query: 1373 ADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVES 1432
D EE+V+ISLSP+YVF VS+F+ELPSLEQKLL PI TLT++QI++LL P V
Sbjct: 1379 MDPEEMVQISLSPDYVFQVSSFQELPSLEQKLLAPIETLTADQIRQLLGDVT-TIPDVSG 1437
Query: 1433 DAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKT 1492
+ D+VFLIDSS+ VR DG AHIRDF+SRIV++L++GP+KVR+GVVQFSN+VFPEFYL+T
Sbjct: 1438 EEKDVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVGPNKVRIGVVQFSNNVFPEFYLRT 1497
Query: 1493 YRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKS 1552
++S+ VL AIRRLRLRGG P+N GKAL++V +N F+KSAGSRIEDGVPQHLV++LG +S
Sbjct: 1498 HKSKNAVLQAIRRLRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQS 1557
Query: 1553 QDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNS 1612
QDDV+R A VI S+ I LGVG RN+DR +LQ ITNDP V V++F LP +E ++ N
Sbjct: 1558 QDDVNRPANVISSTSIQPLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNI 1617
Query: 1613 FGPSXXXXXXXXXXXXXXSRPE-KKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYE 1671
PE KK+ADIVFLLDGSIN RD+FQEVL+FV IVD +YE
Sbjct: 1618 L----EELTVPTTEGPVYPGPEGKKQADIVFLLDGSINLGRDNFQEVLQFVYSIVDAIYE 1673
Query: 1672 DGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHF 1731
DGDSIQVGL QYNSD TDEFFLKD+S+K +I+DAINKV+YKGGR ANT ++HL+ HF
Sbjct: 1674 DGDSIQVGLAQYNSDVTDEFFLKDYSSKPEILDAINKVIYKGGRVANTGAAIKHLQAKHF 1733
Query: 1732 VPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIAS 1791
V EAGSR+DQRVPQIAF+ITGGKS +D Q S+ + Q+GVKVFAVGVRNID EEV K+AS
Sbjct: 1734 VKEAGSRIDQRVPQIAFIITGGKSSDDGQGASMEVAQKGVKVFAVGVRNIDLEEVSKLAS 1793
Query: 1792 NSATAFRVGNXXXXXXXXXXXXXXXHDAMHETLCPGVTDAAKACNLDVILGFDGS---RD 1848
SAT+FRV AM E LCPG TD + C+LDVILGFD S
Sbjct: 1794 ESATSFRVSTAQELSELNEQVLVTLAAAMKEKLCPGTTDVTRDCDLDVILGFDVSDVGAG 1853
Query: 1849 QNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQP 1908
QN+F +Q+G ES+V+A+LNRI+QM ++SC+G R+P+VRV+++A + GPVE DF EYQP
Sbjct: 1854 QNIFNSQRGLESRVEAVLNRITQMQKISCTGSRAPSVRVAIMAQSRGGPVEGLDFSEYQP 1913
Query: 1909 EMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASEN 1968
E+ E+F+ MR++ PY LT +TLK Y NKFR + S KVVIHFTDG D L + AS +
Sbjct: 1914 ELFERFQGMRTRGPYFLTAETLKSYQNKFRSAPSGSTKVVIHFTDGTDDYLDQMKTASAD 1973
Query: 1969 LRQEGVRALILVGLERVVNLERLMHLEFGRGFMXXXXXXXXXXXXXXXXAEQLDNIAEKA 2028
LR++GV AL+ VGL+RV N E +M LEFGRGF AEQLDNIAE+
Sbjct: 1974 LRRQGVHALLFVGLDRVKNFEEVMQLEFGRGFTYNRPLRVNLLDLDFELAEQLDNIAERT 2033
Query: 2029 CCGVPCKCSGQRGDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXVNGTQGFQGCP 2088
CCGVPCKCSGQRGDR VNGTQGFQGCP
Sbjct: 2034 CCGVPCKCSGQRGDRGLPGPIGPKGATGEIGYGGYPGDEGGPGERGPPGVNGTQGFQGCP 2093
Query: 2089 GQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDKGPRGEKGER 2148
G RG KGSRGFPGEK SGEKG GRRG KG +GE+GER
Sbjct: 2094 GHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGFSGEKGFSGRRGSKGAKGERGER 2153
Query: 2149 GDVGIRGDPGNPGQDSQERGPKGETGDL 2176
GD G+RGDPG G D+ +RG +G+ G++
Sbjct: 2154 GDRGLRGDPGESGADNTQRGTRGQKGEI 2181
Score = 730 bits (1865), Expect = 0.0
Identities = 356/561 (63%), Positives = 431/561 (76%), Gaps = 1/561 (0%)
Query: 2295 DDGRDXXXXXXXXXXXXXXXFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
DDGRD F GYPGPKG PG+ G G GPKG RGRRGN+G PG GQ
Sbjct: 2300 DDGRDGIGGPGPKGRKGERGFVGYPGPKGGPGDRGGAGGPGPKGNRGRRGNAGNPGTPGQ 2359
Query: 2355 KXXXXXXXXXXXXXXXXDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVN 2414
K SI QCAL+Q+IKDKCPCCYGP ECPVFPTELAFA+DTS GV
Sbjct: 2360 KGEIGYPGPSGLKGDKGPSISQCALVQNIKDKCPCCYGPKECPVFPTELAFAIDTSSGVG 2419
Query: 2415 QDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIK 2474
+D F RM+ VL +V+ LTIAESNCP GARVA+VTYNNEVTTEIRFAD+++KS LL +I+
Sbjct: 2420 RDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFADARKKSSLLQQIQ 2479
Query: 2475 NLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLS 2534
N Q LT+K +SLETAMSFVARNTFKR R+GFLMRKVAVFFSN TRASPQL +AVLKL
Sbjct: 2480 NFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRKVAVFFSNGETRASPQLNDAVLKLY 2539
Query: 2535 DAGITPLFLTRQEDRQLINALQINNTAVGHALVLP-AGRDLTDFLENVLTCHVCLDICNI 2593
DAG+TP+FLT ++D L AL+INNTAVGHA+VLP +G L D + +LTCHVCLD+C
Sbjct: 2540 DAGVTPVFLTSRQDAVLERALEINNTAVGHAIVLPTSGSQLNDTIRRLLTCHVCLDVCEP 2599
Query: 2594 DPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSP 2653
DP CG+GS RP FRDRRAA +DVD D+AFI+DS+ +TT QFNEMKKYI++LV +++S
Sbjct: 2600 DPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSASTTPLQFNEMKKYISHLVSNMEISS 2659
Query: 2654 DPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTR 2713
+PK SQH ARVAV+Q AP + N+S PPVK EFSLTDYGSKEK++++L MTQL GT
Sbjct: 2660 EPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGSKEKIINYLHNQMTQLYGTM 2719
Query: 2714 ALGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLG 2773
A+GSA+E+T+ +VFESAPNPRDLK++VLM+TG++ +Q+LE + ++ AKCKGY FV+LG
Sbjct: 2720 AMGSAVEHTVAHVFESAPNPRDLKVIVLMITGKMEKQELEYLREAVIDAKCKGYLFVILG 2779
Query: 2774 IGRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIR 2833
IG+ V++K +Y+ ASEPNDVFFKLV K EL+EEPL+RFGRLLPSF+ S+ AFYLSP+IR
Sbjct: 2780 IGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPLLRFGRLLPSFIRSDFAFYLSPEIR 2839
Query: 2834 KQCDWFQGDQPTKNLVKFGHK 2854
KQC W Q DQ K+ G K
Sbjct: 2840 KQCKWLQADQTPKSPGHTGQK 2860
Score = 211 bits (532), Expect = 9e-53
Identities = 99/188 (52%), Positives = 127/188 (66%), Gaps = 10/188 (5%)
Query: 2991 LREVQVFEITENSAKLHWERPEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGGLLAG 3050
+ ++Q+ ++TENSA+L W PEP Y +DL +T AHD SLVLKQN+T T+RVIGGL +G
Sbjct: 2958 MNDIQITDVTENSARLRWASPEPHNAYVFDLAITLAHDHSLVLKQNVTGTERVIGGLRSG 3017
Query: 3051 QTYHVAVVCYLRSQVRATYHGSFXXXXXXXXXXXXXXXXXXXXINLMVSTEPLALTET-- 3108
Q Y V + YL+SQ + TY G+F N+M++ EPL E
Sbjct: 3018 QKYLVFITGYLKSQPKVTYTGTFSTKTPAQPKVALA--------NMMLNAEPLEGPENVM 3069
Query: 3109 DICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVLAKP 3168
DIC L K+EGTCRDF+LKW+YD TKSCARFWYGGCGGNEN+F +QKECEK C+P P
Sbjct: 3070 DICLLQKEEGTCRDFVLKWHYDLKTKSCARFWYGGCGGNENRFNTQKECEKACSPGNISP 3129
Query: 3169 GVISVMGT 3176
GV++ +GT
Sbjct: 3130 GVVTTIGT 3137
Score = 68.3 bits (164), Expect = 1e-09
Identities = 87/412 (21%), Positives = 171/412 (41%), Gaps = 69/412 (16%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
+L F +D S+ + F +RD +++++ L + G VV Y+++ TE
Sbjct: 241 DLIFLIDGSDNIGSVNFQAIRDFLVNLIESLRVGAQQIHIG----VVQYSDQPRTEFALN 296
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVA-VFFSNTPT 2520
K+ +LD +K L K+ + A+ +V N F + + V + +
Sbjct: 297 SYSTKADVLDAVKALSFR-GGKEANTGAALEYVVENLFTQAGGSRIEEAVPQILVLISGG 355
Query: 2521 RASPQLREAVLKLSDAGITPLFL-----TRQEDRQL-------INALQINNTAVGHALVL 2568
+S +RE +L + A I + E +Q+ AL I N A L+L
Sbjct: 356 ESSDDIREGLLAVKQASIFSFSIGVLNADSAELQQIATDGSFAFTALDIRNLAALRELLL 415
Query: 2569 PAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAE 2628
P + L + + ++ ++ D+ F++D +
Sbjct: 416 PNIVGVAQRLILLEAPTIVTEVIEVNKK----------------------DIVFLIDGST 453
Query: 2629 TTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFS 2688
FN ++ ++A +V++L++ PD +VAV Q+A + V+ EF
Sbjct: 454 ALGTGPFNSIRDFVAKIVQRLEVGPD------LIQVAVAQYADT----------VRPEFY 497
Query: 2689 LTDYGSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR---DLKIVVLML 2743
+ +++ ++ + + +L G AL GSA+++ N F SA R + +++++
Sbjct: 498 FNTHQNRKDVMANVKK--MKLMGGTALNTGSALDFVRNNFFTSAAGCRMEEGVLPMLVLI 555
Query: 2744 TGEVPEQQLEEAQRVILQAKCKGYFFVVLGIG-RKVNIKEVYTFASEPNDVF 2794
TG +E+A A+ K V+L +G R ++ E+ A E + VF
Sbjct: 556 TGGKSMDAVEQA-----AAEMKRNRIVILAVGSRNADVAELQEIAHERDFVF 602
Score = 66.7 bits (160), Expect = 4e-09
Identities = 86/408 (21%), Positives = 169/408 (41%), Gaps = 60/408 (14%)
Query: 828 PLAQPESKRDILFLFDGSANLVGQ--FPVVRDFLYKIIDELNVK----PEGTRIAVAQYS 881
P P ++ F D S+ VG+ F ++ + +++ L + P G R+A+ Y+
Sbjct: 2398 PKECPVFPTELAFAIDTSSG-VGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYN 2456
Query: 882 DDVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGV 940
++V E RF + + K +L ++ + T K +L A+ + R F R G
Sbjct: 2457 NEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTF-----KRARSGF 2511
Query: 941 LQFLVLLVAG----RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAA 996
L V + R+S +++ L +GV P +F D + ++ + A
Sbjct: 2512 LMRKVAVFFSNGETRASPQLNDAVLKLYDAGVTP-VFLTSRQDAVLERALEINNTAVGHA 2570
Query: 997 ESLPKIGDLHPQIVNLLKSVH----------------------NGAPAPVSGEKDVVFLL 1034
LP G + L + H + AP + D+ F++
Sbjct: 2571 IVLPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIM 2630
Query: 1035 DGSEGVRS-GFPLLKEFVQRVVESLD------VGQDRVRVAVVQ---YSDRT-------R 1077
D S F +K+++ +V +++ + Q RVAV+Q Y T +
Sbjct: 2631 DSSASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVK 2690
Query: 1078 PEFYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLL 1136
EF L Y +K+ ++N + Q+T L G T G+A+E + ++ S+ R + + ++
Sbjct: 2691 TEFSLTDYGSKEKIINYLHNQMTQLYG-TMAMGSAVEHTVAHVFESAPNPRDLKVIVLMI 2749
Query: 1137 IVLTADRSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 1183
+ + +R + K G + + +GIG N D+ + +++ P+
Sbjct: 2750 TGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPN 2797
Score = 65.2 bits (156), Expect = 1e-08
Identities = 95/446 (21%), Positives = 176/446 (39%), Gaps = 58/446 (13%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D+S+ V D +RD + IV L + P R+ VV ++N V E
Sbjct: 1441 DVVFLIDSSDSVRSDGLAHIRDFISRIVQQLDVG----PNKVRIGVVQFSNNVFPEFYLR 1496
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFLMRKVAVFFS 2516
K K+ +L I+ L++ + A+ +V +N F R+ +G V +
Sbjct: 1497 THKSKNAVLQAIRRLRLR-GGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGD 1555
Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFL-TRQEDRQLINALQINNTAVGHALVLPAGRDLT 2575
++ + +S I PL + R DR N LQ+ G LV+ L
Sbjct: 1556 ----QSQDDVNRPANVISSTSIQPLGVGARNVDR---NQLQVITNDPGRVLVVQDFTGLP 1608
Query: 2576 DFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQF 2635
V L + + G P ++ A D+ F+LD + F
Sbjct: 1609 TLERKVQNILEELTVPTTE-----GPVYPGPEGKKQA------DIVFLLDGSINLGRDNF 1657
Query: 2636 NEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSK 2695
E+ +++ +V + D +V + Q+ V EF L DY SK
Sbjct: 1658 QEVLQFVYSIVDAIYEDGDS------IQVGLAQYNSD----------VTDEFFLKDYSSK 1701
Query: 2696 EKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR-DLKI--VVLMLTGEVPEQQL 2752
+++D +++ + + G+AI++ F R D ++ + ++TG +
Sbjct: 1702 PEILDAINKVIYKGGRVANTGAAIKHLQAKHFVKEAGSRIDQRVPQIAFIITG---GKSS 1758
Query: 2753 EEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVF-FKLVDKSTELNEEPLMR 2811
++ Q ++ KG +G+ R ++++EV ASE F + +ELNE+ L+
Sbjct: 1759 DDGQGASMEVAQKGVKVFAVGV-RNIDLEEVSKLASESATSFRVSTAQELSELNEQVLVT 1817
Query: 2812 FGRLLPSFVSSENAFYLSPDIRKQCD 2837
+ E + D+ + CD
Sbjct: 1818 LAAAM-----KEKLCPGTTDVTRDCD 1838
Score = 65.2 bits (156), Expect = 1e-08
Identities = 99/426 (23%), Positives = 178/426 (41%), Gaps = 90/426 (21%)
Query: 2392 GPLECPVFPTE----LAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAV 2447
G E P+ PTE + F +D S + +F +RD + +++ L + P RVAV
Sbjct: 828 GVEEVPLAPTESKKDILFLIDGSANL-LGSFPAVRDFIHKVISDLNVG----PDATRVAV 882
Query: 2448 VTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRV 2502
+++ + E FA+ K +L K+K +++ T KQ ++ A+ V R F R+
Sbjct: 883 AQFSDNIQIEFDFAELPSKQDMLLKVKRMRLK-TGKQLNIGVALDEVMRRLFVKEAGSRI 941
Query: 2503 RNG---FLMRKVAVFFSNTPTRASPQLREA-----VLKLSDAGIT--------PLFLTRQ 2546
G FL+ A ++ R S L+EA +K +A ++ P F+
Sbjct: 942 EEGIPQFLVLLAAGRSTDEVERPSGALKEAGVVTFAIKAKNADLSELERIAYAPQFILNV 1001
Query: 2547 EDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSF 2606
E I+ LQ N + + L+ + ++P+
Sbjct: 1002 ESLPRISELQAN---------------IVNLLKTI-------------------QFQPTV 1027
Query: 2607 RDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAV 2666
+R D+ F++D ++ F +K ++ +V LD+ D RVA+
Sbjct: 1028 VERGEKK-----DVVFLIDGSDGVRR-GFPLLKTFVERVVESLDIGRDK------VRVAI 1075
Query: 2667 VQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIEN 2725
VQ++ NA P EF L Y K LV + + +T + G+ G+A++Y I+N
Sbjct: 1076 VQYS------NAIQP----EFLLDAYEDKADLVSAI-QALTIMGGSPLNTGAALDYLIKN 1124
Query: 2726 VFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYT 2785
VF + R + V L ++ ++ +R + K G +GIG ++ E+ T
Sbjct: 1125 VFTVSSGSRIAEGVPQFLILLTADRSQDDVRRPSVVLKTSGTVPFGIGIG-NADLTELQT 1183
Query: 2786 FASEPN 2791
+ P+
Sbjct: 1184 ISFLPD 1189
Score = 56.2 bits (133), Expect = 5e-06
Identities = 37/103 (35%), Positives = 48/103 (45%), Gaps = 20/103 (19%)
Query: 2078 VNGTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRR- 2136
V GT+G G PG G +G RG G GE+G PG R
Sbjct: 2213 VKGTKGALGQPGPAGEQGMRGPQGPPGQIGTPGI---------------RGEQGIPGPRA 2257
Query: 2137 --GDKGPRGEKGERGDVGIRGDPGNPGQ--DSQERGPKGETGD 2175
G G GE+G G +G +G+PGNPG + ++GP+GE GD
Sbjct: 2258 GGGQPGAPGERGRIGPLGRKGEPGNPGPRGPNGQQGPRGEMGD 2300
Score = 55.4 bits (131), Expect = 9e-06
Identities = 88/411 (21%), Positives = 168/411 (40%), Gaps = 67/411 (16%)
Query: 1029 DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDR----VRVAVVQYSDRTRPEFYLN 1083
++ F +D S GV R F +K+ V RVV +L + + RVA+V Y++ E
Sbjct: 2407 ELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFA 2466
Query: 1084 SYMNKQDVVNAVR--QLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTA 1141
K ++ ++ Q TL P + A+ FV RN + + V +
Sbjct: 2467 DARKKSSLLQQIQNFQATLTTKPR-SLETAMSFVARNTFKRARSGFLMRKVA-VFFSNGE 2524
Query: 1142 DRSGDDVRNPSVVVKRGGAVPIGIGIGNADITE--MQTISFIPDFAVAIPTF-RQLG-TV 1197
R+ + + + + G P+ + + E ++ + A+ +PT QL T+
Sbjct: 2525 TRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIVLPTSGSQLNDTI 2584
Query: 1198 QQVISERVTQLTREELSRLQPVLQPLPSPGVGGKR---------------DVVFLIDGSQ 1242
+++++ V V +P P G G +R D+ F++D S
Sbjct: 2585 RRLLTCHVCL----------DVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDSSA 2634
Query: 1243 SAGP-EFQYVRTLIERLVDYLDVGFDT------TRVAVIQFSD----------DPKAEFL 1285
S P +F ++ I LV +++ + RVAV+Q + K EF
Sbjct: 2635 STTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFS 2694
Query: 1286 LNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISS 1345
L + SK+++ N + + + +G+A+E+ ++F+ R + +VL+ +
Sbjct: 2695 LTDYGSKEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPR----DLKVIVLMIT 2750
Query: 1346 GKSDD-------EVVVPAVELKQFGVAPFTIARNADQEELVKISLSPEYVF 1389
GK + E V+ A + K + I +N D + + ++ P VF
Sbjct: 2751 GKMEKQELEYLREAVIDA-KCKGYLFVILGIGKNVDVKNIYSLASEPNDVF 2800
Score = 53.5 bits (126), Expect = 4e-05
Identities = 37/99 (37%), Positives = 41/99 (41%), Gaps = 27/99 (27%)
Query: 2079 NGTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGD 2138
+G G G PG +G KG RGF G G KG PG RG
Sbjct: 2301 DGRDGIGG-PGPKGRKGERGFVGYP------------------------GPKGGPGDRGG 2335
Query: 2139 KGPRGEKGERGDVGIRGDPGNPGQDSQ--ERGPKGETGD 2175
G G KG RG G G+PG PGQ + GP G GD
Sbjct: 2336 AGGPGPKGNRGRRGNAGNPGTPGQKGEIGYPGPSGLKGD 2374
Score = 53.1 bits (125), Expect = 5e-05
Identities = 87/443 (19%), Positives = 180/443 (39%), Gaps = 47/443 (10%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D S Q+ F +RD++ IVN L + R++VV ++ E
Sbjct: 1239 DVVFLVDGSRYAAQE-FYLIRDLIERIVNNLDVGFDT----TRISVVQFSEHPHVEFLLN 1293
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTR 2521
K + ++ L+ +Q ++ A+ FVA+ F R + V F +R
Sbjct: 1294 AHSTKDEVQGAVRRLRPR-GGQQVNVGEALEFVAKTIFTRPSGSRIEEGVPQFLVILSSR 1352
Query: 2522 ASPQ-LREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLEN 2580
S L +++ G+ P+ + + D + + + ++ V + + ++L +
Sbjct: 1353 KSDDDLEFPSVQVKQVGVAPMVIAKNMDPEEMVQISLSPDYV---FQVSSFQELPSLEQK 1409
Query: 2581 VLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKK 2640
+L L I G + P S + D+ F++DS+++ ++
Sbjct: 1410 LLAPIETLTADQIRQLLGDVTTIPDV-------SGEEKDVVFLIDSSDSVRSDGLAHIRD 1462
Query: 2641 YIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVD 2700
+I+ +V+QLD+ P+ R+ VVQ + + V EF L + SK ++
Sbjct: 1463 FISRIVQQLDVGPNK------VRIGVVQFSNN----------VFPEFYLRTHKSKNAVLQ 1506
Query: 2701 FLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPR---DLKIVVLMLTGEVPEQQLEEA 2755
+ R +L+G + G A++Y ++N F + R + ++++ G+ + +
Sbjct: 1507 AIRR--LRLRGGYPVNAGKALDYVVKNYFIKSAGSRIEDGVPQHLVVILGDQSQDDVNRP 1564
Query: 2756 QRVILQAKCKGYFFVVLGIG-RKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGR 2814
VI + LG+G R V+ ++ ++P V E +
Sbjct: 1565 ANVISSTSIQ-----PLGVGARNVDRNQLQVITNDPGRVLVVQDFTGLPTLERKVQNILE 1619
Query: 2815 LLPSFVSSENAFYLSPDIRKQCD 2837
L + ++E Y P+ +KQ D
Sbjct: 1620 EL-TVPTTEGPVYPGPEGKKQAD 1641
Score = 52.7 bits (124), Expect = 6e-05
Identities = 33/96 (34%), Positives = 41/96 (42%), Gaps = 23/96 (23%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
G +G QG PG R G G PGE+ G KG PG G +
Sbjct: 2245 GIRGEQGIPGPRAGGGQPGAPGERGRIGPL------------------GRKGEPGNPGPR 2286
Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
GP G++G RG++G G G G GPKG G+
Sbjct: 2287 GPNGQQGPRGEMGDDGRDGIGGP-----GPKGRKGE 2317
Score = 51.5 bits (121), Expect = 1e-04
Identities = 86/412 (20%), Positives = 162/412 (38%), Gaps = 46/412 (11%)
Query: 1425 YPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIG----PSKVRVGVVQF 1480
Y P ++ F ID+S GV D F ++ V R+V L I P RV +V +
Sbjct: 2396 YGPKECPVFPTELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTY 2455
Query: 1481 SNDVFPEFYLKTYRSQAPVLDAIRRLRLR-GGSPLNTGKALEFVARNLFVKSAGSRIEDG 1539
+N+V E R ++ +L I+ + P + A+ FVARN F ++ +
Sbjct: 2456 NNEVTTEIRFADARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFLMRK 2515
Query: 1540 VPQHLVLVLGGKSQDDVSRFAQVIR--SSGIVSLGVGDRN---IDRTELQTITNDPRLVF 1594
V V G+++ V++ +G+ + + R ++R T +
Sbjct: 2516 V---AVFFSNGETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIV 2572
Query: 1595 TVREFRELPNIEERIMNSF--------GPSXXXXXXXXXXXXXXSRPEKKKADIVFLLDG 1646
+L + R++ P + P DI F++D
Sbjct: 2573 LPTSGSQLNDTIRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDTDIAFIMDS 2632
Query: 1647 SINFRRDSFQEVLRFVSEIVDTVYEDGD------SIQVGLVQ---YNSDPTD-------E 1690
S + F E+ +++S +V + + +V ++Q Y+ + E
Sbjct: 2633 SASTTPLQFNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTE 2692
Query: 1691 FFLKDFSTKRQIIDAI-NKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFV 1749
F L D+ +K +II+ + N++ G A +EH V H A + D +V I +
Sbjct: 2693 FSLTDYGSKEKIINYLHNQMTQLYGTMAMGS-AVEH-TVAHVFESAPNPRDLKV--IVLM 2748
Query: 1750 ITGGKSVEDAQDVSLALTQ---RGVKVFAVGV-RNIDSEEVGKIASNSATAF 1797
ITG ++ + + A+ +G +G+ +N+D + + +AS F
Sbjct: 2749 ITGKMEKQELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVF 2800
Score = 47.3 bits (110), Expect = 0.003
Identities = 22/44 (50%), Positives = 27/44 (61%), Gaps = 3/44 (6%)
Query: 2315 FPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
+ GYPG +G PGE PG+NGT G +G G RG G G G+K
Sbjct: 2065 YGGYPGDEGGPGERGPPGVNGTQGFQGCPGHRGTKGSRGFPGEK 2108
Score = 46.1 bits (107), Expect = 0.006
Identities = 30/97 (30%), Positives = 41/97 (41%), Gaps = 2/97 (2%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
GT+G +G GQ G G G G+ + G+ G G +G +
Sbjct: 2173 GTRGQKGEIGQMGEPGPAGQRGQDGGVGRKGMAGRRGPIGVKGTKGALGQPGPAGEQGMR 2232
Query: 2140 GPRGEKGERGDVGIRGDPGNPG--QDSQERGPKGETG 2174
GP+G G+ G GIRG+ G PG + G GE G
Sbjct: 2233 GPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGERG 2269
Score = 45.7 bits (106), Expect = 0.008
Identities = 94/442 (21%), Positives = 165/442 (37%), Gaps = 82/442 (18%)
Query: 2394 LECPVFPTE--------LAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARV 2445
LE P TE + F +D S + F +RD V IV L + P +V
Sbjct: 428 LEAPTIVTEVIEVNKKDIVFLIDGSTALGTGPFNSIRDFVAKIVQRLEVG----PDLIQV 483
Query: 2446 AVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTFK----- 2500
AV Y + V E F + + ++ +K +++ + + +A+ FV N F
Sbjct: 484 AVAQYADTVRPEFYFNTHQNRKDVMANVKKMKL-MGGTALNTGSALDFVRNNFFTSAAGC 542
Query: 2501 RVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNT 2560
R+ G L V + T ++ + +A ++ + +R +I A+ N
Sbjct: 543 RMEEGVLPMLVLI----TGGKSMDAVEQAAAEM------------KRNRIVILAVGSRNA 586
Query: 2561 AVGHALVLPAGRDLT--------DFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAA 2612
V + RD F++ +L V I + PS + +
Sbjct: 587 DVAELQEIAHERDFVFQPNDFRLQFMQAILP-EVLSPIRTLSGGMVIHE-TPSVQVTKR- 643
Query: 2613 GSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPS 2672
D+ F+LD + F ++ ++ LV LD+ D RV +VQ + +
Sbjct: 644 ------DIIFLLDGSLNVGNANFPFVRDFVVTLVNYLDVGTDK------IRVGLVQFSDT 691
Query: 2673 ESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAP- 2731
K EFSL Y +K ++ L + + GSA+ + + N F A
Sbjct: 692 P----------KTEFSLYSYQTKSDIIQRLGQLRPKGGSVLNTGSALNFVLSNHFTEAGG 741
Query: 2732 ---NPRDLKIVVLMLTGE--VPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTF 2786
N + +++VL+ G VP Q+ G +G+ R + E+
Sbjct: 742 SRINEQVPQVLVLVTAGRSAVPFLQVSN------DLARAGVLTFAVGV-RNADKAELEQI 794
Query: 2787 ASEPNDVFFKLVDKSTELNEEP 2808
A P V+F +D ++L P
Sbjct: 795 AFNPKMVYF--MDDFSDLTTLP 814
Score = 43.0 bits (99), Expect = 0.053
Identities = 21/42 (50%), Positives = 24/42 (57%), Gaps = 3/42 (7%)
Query: 2317 GYPGPK---GNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G PGP+ G PG PG G GP G +G GN GP G GQ+
Sbjct: 2251 GIPGPRAGGGQPGAPGERGRIGPLGRKGEPGNPGPRGPNGQQ 2292
Score = 43.0 bits (99), Expect = 0.053
Identities = 85/419 (20%), Positives = 162/419 (38%), Gaps = 57/419 (13%)
Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 297
++ F ID S+ G F + ++ ++ L I RV +V +++E T
Sbjct: 2407 ELAFAIDTSSGVGRDVFNRMKQTVLRVVSNLTIAESNCPRGARVALVTYNNEVTTEIRFA 2466
Query: 298 TYSTKAQVLGAVKAL-GFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAG 356
K+ +L ++ + ++ A+ FV N F RA + + +V V S G
Sbjct: 2467 DARKKSSLLQQIQNFQATLTTKPRSLETAMSFVARNTFKRARSGFL---MRKVAVFFSNG 2523
Query: 357 PS--SDEIRYGVVALKQASVFSFGLGAQ---AASRA-ELQHIATDDNLVFTVPEFRSFGD 410
+ S ++ V+ L A V L ++ RA E+ + A +V +
Sbjct: 2524 ETRASPQLNDAVLKLYDAGVTPVFLTSRQDAVLERALEINNTAVGHAIVLPTSGSQLNDT 2583
Query: 411 LQEKLLPY----------IVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLAN 460
++ L + I G + V + ++ DI F++D S++
Sbjct: 2584 IRRLLTCHVCLDVCEPDPICGYGSQRPVFRDRRAAPTDVDT---DIAFIMDSSASTTPLQ 2640
Query: 461 FNAIRDFIAKVIQRLE------IGQDLIQVAVAQYA----------DTVRPEFYFNTHPT 504
FN ++ +I+ ++ +E I Q +VAV Q A V+ EF + +
Sbjct: 2641 FNEMKKYISHLVSNMEISSEPKISQHHARVAVLQQAPYDHETNSSFPPVKTEFSLTDYGS 2700
Query: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGK---- 560
K ++I + + GSA++ ++F S+ R K++VL+ GK
Sbjct: 2701 KEKIINYLHNQMTQLYGTMAMGSAVEHTVAHVFESAPNPRDL----KVIVLMITGKMEKQ 2756
Query: 561 SLDEISQPAQELKRSSIMAFAIG-NKGADQAELEEIAFDSSLVFI-----PAEFRAAPL 613
L+ + + + K + +G K D + +A + + VF P E PL
Sbjct: 2757 ELEYLREAVIDAKCKGYLFVILGIGKNVDVKNIYSLASEPNDVFFKLVSKPGELHEEPL 2815
Score = 41.0 bits (94), Expect = 0.20
Identities = 27/82 (32%), Positives = 34/82 (40%), Gaps = 24/82 (29%)
Query: 2080 GTQGFQGCPGQRGVKGSRGF---PGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRR 2136
G +GF G PG +G G RG PG K + G +GN G
Sbjct: 2316 GERGFVGYPGPKGGPGDRGGAGGPGPKG---------------------NRGRRGNAGNP 2354
Query: 2137 GDKGPRGEKGERGDVGIRGDPG 2158
G G +GE G G G++GD G
Sbjct: 2355 GTPGQKGEIGYPGPSGLKGDKG 2376
Score = 39.5 bits (90), Expect = 0.60
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G+PG KG GE GL+G G +G +G G SG G G++
Sbjct: 2103 GFPGEKGELGEMGLDGIDGEEGDKGLPGFSGEKGFSGRR 2141
Score = 38.7 bits (88), Expect = 1.0
Identities = 17/39 (43%), Positives = 22/39 (55%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G GP+G PG+ G G G +GI G R G PG G++
Sbjct: 2230 GMRGPQGPPGQIGTPGIRGEQGIPGPRAGGGQPGAPGER 2268
Score = 38.3 bits (87), Expect = 1.3
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 3/43 (6%)
Query: 2316 PGYPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
PG+ G KG+ PGE G G G GI G G+ G PG G+K
Sbjct: 2093 PGHRGTKGSRGFPGEKGELGEMGLDGIDGEEGDKGLPGFSGEK 2135
Score = 37.9 bits (86), Expect = 1.8
Identities = 18/37 (48%), Positives = 20/37 (53%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353
G GP G G G G GP G +G RG GPPG +G
Sbjct: 2206 GRRGPIGVKGTKGALGQPGPAGEQGMRGPQGPPGQIG 2242
Score = 37.5 bits (85), Expect = 2.3
Identities = 18/38 (47%), Positives = 20/38 (52%)
Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353
PG+ G KG G G G G +G RG RG G PG G
Sbjct: 2129 PGFSGEKGFSGRRGSKGAKGERGERGDRGLRGDPGESG 2166
Score = 36.0 bits (81), Expect = 6.8
Identities = 17/45 (37%), Positives = 24/45 (52%), Gaps = 6/45 (13%)
Query: 2317 GYPGPKGNPGEPG------LNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G PGP G G+ G + G GP G++G +G G PG G++
Sbjct: 2185 GEPGPAGQRGQDGGVGRKGMAGRRGPIGVKGTKGALGQPGPAGEQ 2229
>gb|AAC23667.1| (AF064749) type VI collagen alpha 3 subunit [Mus musculus]
Length = 2657
Score = 2197 bits (5631), Expect = 0.0
Identities = 1127/1541 (73%), Positives = 1257/1541 (81%), Gaps = 8/1541 (0%)
Query: 636 NKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNT 695
NKRDI+FL+DGS+++G +NF +RDFV ++ L+IG D ++V + Q++DT EF LN+
Sbjct: 34 NKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVSPEFYLNS 93
Query: 696 YQTKSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQS 755
Y K D S+L +V N FT + G R E VP+LL+L+T G+S
Sbjct: 94 YTNKRDAVTAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKS 153
Query: 756 EDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSXXXXXXXXXXX 815
D Q A L R I+ VG+ A++ EL++IAF+ SLV++ +F
Sbjct: 154 LDEVSQPARELKRGSIMALAVGSKAADEDELKEIAFDSSLVFIPAEFRPAPLQNMLPSLM 213
Query: 816 XTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRI 875
G E SKRDILFLFDGS N++GQFP VRDFLY+ I+EL+VKP+GTR+
Sbjct: 214 APLRTLTGTTE------GSKRDILFLFDGSVNVLGQFPAVRDFLYRFIEELDVKPDGTRV 267
Query: 876 AVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSR 935
A+AQ+SDDV++ESRF EHQ+K EILNLVK+MK+KTGKALNLGYALDYA R IFV+SAGSR
Sbjct: 268 AIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSAGSR 327
Query: 936 IEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILA 995
IED V QFLVLLVAGRSSD V GPAS+LKQ GVVPFIFQAKNA+P+ELEQIVLSPAFILA
Sbjct: 328 IEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILA 387
Query: 996 AESLPKIGDLHPQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVRSGFPLLKEFVQRVV 1055
AESLPKIGDL QIV+LLK+ P VSGEKDVVFL+DGSEGVRSGFPLLK+FVQRVV
Sbjct: 388 AESLPKIGDLQSQIVSLLKAEQGSGP--VSGEKDVVFLIDGSEGVRSGFPLLKDFVQRVV 445
Query: 1056 ESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFV 1115
ESLDVG DRVRVA+VQYSDRTRPEFYLNS+M++Q V++A+R+LTLLGG TPNTGAALEFV
Sbjct: 446 ESLDVGPDRVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGTTPNTGAALEFV 505
Query: 1116 LRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEM 1175
LRNIL SS GSRI EGVPQLLIVLTA+ SGDDVR PSVV+K+GGAVPIGIGIGNADI+EM
Sbjct: 506 LRNILTSSTGSRIAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIGNADISEM 565
Query: 1176 QTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVV 1235
QTISFIPDFAVAIPTFR+LGT+Q+VISERV QL REELS L+P+L P GVG K+DVV
Sbjct: 566 QTISFIPDFAVAIPTFRELGTIQRVISERVIQLNREELSSLKPILTPSTGAGVGSKKDVV 625
Query: 1236 FLIDGSQSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEV 1295
FLIDGS++AGPEFQY+RT IER+V+YLD+GFDTTRVAVIQFS+D K EF LNAH SKDEV
Sbjct: 626 FLIDGSRNAGPEFQYIRTQIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAHFSKDEV 685
Query: 1296 QNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVP 1355
QN V+RLRPKGG Q+ +GNALEYV +NIF+RPLGSRIEEGVPQFLVLISSGK DDEV
Sbjct: 686 QNTVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKYDDEVDDS 745
Query: 1356 AVELKQFGVAPFTIARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPITTLTSEQ 1415
AVELKQFGVAP TIAR+ DQEELVKISLSPEYV+SVSTFRELP LEQKLLTPITTLTS+Q
Sbjct: 746 AVELKQFGVAPLTIARHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPITTLTSQQ 805
Query: 1416 IQKLLASTRYPPPAVESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRV 1475
I ++LASTRYPP VESDAADIVFLIDSS+ V+PDG AHIRDFVSRIVRRLNIGPSKVR+
Sbjct: 806 IHQILASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRI 865
Query: 1476 GVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSR 1535
GVVQFSNDVFPEFYLKT++SQ+ VL+AIRRLR +GGSPLNTG+ALEFVARNLFVKSAGSR
Sbjct: 866 GVVQFSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSR 925
Query: 1536 IEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFT 1595
IEDGVPQHLVL LGGKSQDDV+R AQVI SSGIVSLG+GDRNIDRT+LQTITNDPRLVFT
Sbjct: 926 IEDGVPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLVFT 985
Query: 1596 VREFRELPNIEERIMNSFGPSXXXXXXXXXXXXXXSRPEKKKADIVFLLDGSINFRRDSF 1655
VREFRELPNIEER+M SFGPS SRPEKKKADIVFLLDGSINFRRDSF
Sbjct: 986 VREFRELPNIEERVMLSFGPSGATPQPPGVDLPSPSRPEKKKADIVFLLDGSINFRRDSF 1045
Query: 1656 QEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGR 1715
QEVLRF S IVDTVYEDGDSI+VGLVQYNSDPTDEFFL+DFSTKRQIIDAINKVVYKGGR
Sbjct: 1046 QEVLRFASVIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAINKVVYKGGR 1105
Query: 1716 HANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFA 1775
HANT+VG+EHL NHFVPEAGSRLD RVPQIAFVITGGKSVEDAQDVSLALTQ+GVKVFA
Sbjct: 1106 HANTRVGIEHLLRNHFVPEAGSRLDVRVPQIAFVITGGKSVEDAQDVSLALTQKGVKVFA 1165
Query: 1776 VGVRNIDSEEVGKIASNSATAFRVGNXXXXXXXXXXXXXXXHDAMHETLCPGVTDAAKAC 1835
VGVRNIDSEEVGKIASNSATAFRVG+ HDAMHETLCPGVTD +KAC
Sbjct: 1166 VGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMHETLCPGVTDVSKAC 1225
Query: 1836 NLDVILGFDGSRDQNVFVAQKGFESKVDAILNRISQMHRVSCSGGRSPTVRVSVVANTPS 1895
NL+VILGFDGSRDQNVFV+QKG ESKVD ILNR SQ+ R+SCSG + PTVRVSV+ANTPS
Sbjct: 1226 NLEVILGFDGSRDQNVFVSQKGLESKVDIILNRTSQIQRISCSGNQLPTVRVSVMANTPS 1285
Query: 1896 GPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTLKVYLNKFRQSSPDSVKVVIHFTDGA 1955
GPVEAFDF EYQPE+ EKFRNMRSQ PYVLT DTLK+Y NKFRQSSPD+VKVVIHFTDGA
Sbjct: 1286 GPVEAFDFAEYQPELFEKFRNMRSQRPYVLTADTLKLYQNKFRQSSPDTVKVVIHFTDGA 1345
Query: 1956 DGDLADLHRASENLRQEGVRALILVGLERVVNLERLMHLEFGRGFMXXXXXXXXXXXXXX 2015
DGD+ADL+RASE LRQ G +ALILVGLERV NLERLMHLEFGRGFM
Sbjct: 1346 DGDMADLYRASEELRQAGAQALILVGLERVANLERLMHLEFGRGFMYDRPLRLNLLDLDY 1405
Query: 2016 XXAEQLDNIAEKACCGVPCKCSGQRGDRXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 2075
AEQLDNIAEKACCGVPCKCSG+RGDR
Sbjct: 1406 ELAEQLDNIAEKACCGVPCKCSGERGDRGPIGSIGPKGISGEDGYRGYPGDEGDPGERGP 1465
Query: 2076 XXVNGTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGR 2135
VNGTQGFQGCPGQRGVKGSRGFPGEK SSGEKG+PGR
Sbjct: 1466 PGVNGTQGFQGCPGQRGVKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGR 1525
Query: 2136 RGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGDL 2176
RGDKGP+G+KGERGDVGIRGDPG+ G+DSQ+RGPKGETGD+
Sbjct: 1526 RGDKGPKGDKGERGDVGIRGDPGDSGRDSQQRGPKGETGDI 1566
Score = 950 bits (2429), Expect = 0.0
Identities = 469/561 (83%), Positives = 493/561 (87%)
Query: 2295 DDGRDXXXXXXXXXXXXXXXFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
DDGRD FPGYPGPKG PGEPG +G GPKGIRGRRGNSGPPG GQ
Sbjct: 1685 DDGRDGVGSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGATGQ 1744
Query: 2355 KXXXXXXXXXXXXXXXXDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVN 2414
K DS+DQCALIQSI+DKCPCCYGPLECPV PTELAFALDTSEGV
Sbjct: 1745 KGDPGYPGPSGHKGNRGDSVDQCALIQSIRDKCPCCYGPLECPVLPTELAFALDTSEGVT 1804
Query: 2415 QDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIK 2474
QDTF RMR+V+L IV LTIAESNCP GARVAVVTYNNEVTTEIRFA SK+KS LLD I+
Sbjct: 1805 QDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFASSKKKSALLDSIQ 1864
Query: 2475 NLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLS 2534
NLQVALTSKQQSLETAMSFVARNTFKRVR+GF MRKVAVFFSN PTRASPQLREAVLKLS
Sbjct: 1865 NLQVALTSKQQSLETAMSFVARNTFKRVRSGFPMRKVAVFFSNKPTRASPQLREAVLKLS 1924
Query: 2535 DAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNID 2594
DAGITPLFLT QEDRQLINALQINNTAVGHALVLPA RDLTDFL+NVLTCHVCLDICNID
Sbjct: 1925 DAGITPLFLTSQEDRQLINALQINNTAVGHALVLPARRDLTDFLKNVLTCHVCLDICNID 1984
Query: 2595 PSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPD 2654
PSCGFGSWRPSFRDRRAAGSDVDID+AFILDS+E TTLFQFNEMKKYI Y++RQLD+SPD
Sbjct: 1985 PSCGFGSWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFNEMKKYIGYVIRQLDLSPD 2044
Query: 2655 PKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA 2714
PKASQHFARVAVVQ + ESVDNAS+PPVKVEFSLTDYG+KEKL+DFLSR MTQLQGT
Sbjct: 2045 PKASQHFARVAVVQQSTYESVDNASVPPVKVEFSLTDYGAKEKLLDFLSRRMTQLQGTMG 2104
Query: 2715 LGSAIEYTIENVFESAPNPRDLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGI 2774
LG+AIEYTIEN+FESAPNPRDLKI+VLMLTG++ QQLEEAQR ILQAKCKGYF VVLGI
Sbjct: 2105 LGNAIEYTIENIFESAPNPRDLKIMVLMLTGDMQRQQLEEAQRAILQAKCKGYFLVVLGI 2164
Query: 2775 GRKVNIKEVYTFASEPNDVFFKLVDKSTELNEEPLMRFGRLLPSFVSSENAFYLSPDIRK 2834
GRKVNIKEVY+FASEPNDVFFK VDKSTELNEEPLMRFGRLLPSFVSSENAFYL PD RK
Sbjct: 2165 GRKVNIKEVYSFASEPNDVFFKFVDKSTELNEEPLMRFGRLLPSFVSSENAFYLPPDFRK 2224
Query: 2835 QCDWFQGDQPTKNLVKFGHKQ 2855
QCDWFQGDQP KN VKFGHKQ
Sbjct: 2225 QCDWFQGDQPVKNGVKFGHKQ 2245
Score = 892 bits (2281), Expect = 0.0
Identities = 500/1191 (41%), Positives = 718/1191 (59%), Gaps = 31/1191 (2%)
Query: 438 VIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEF 497
V+EVNKRDIVFLVDGSS+LG +NFNAIRDF+ +VIQRLEIGQDL+QV+VAQYADTV PEF
Sbjct: 30 VMEVNKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVSPEF 89
Query: 498 YFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLIT 557
Y N++ KR+ +TAVRKM+ L+GSALYTGS+LDFVRNNLFTSSAG+RAAEG+PKLLVLIT
Sbjct: 90 YLNSYTNKRDAVTAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLIT 149
Query: 558 GGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGML 617
GGKSLDE+SQPA+ELKR SIMA A+G+K AD+ EL+EIAFDSSLVFIPAEFR APLQ ML
Sbjct: 150 GGKSLDEVSQPARELKRGSIMALAVGSKAADEDELKEIAFDSSLVFIPAEFRPAPLQNML 209
Query: 618 PGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIR 677
P L+APLRTL+GT E +KRDI+FL DGS NV FP VRDF+ + LD+ D R
Sbjct: 210 PSLMAPLRTLTGTTE--GSKRDILFLFDGSVNV-LGQFPAVRDFLYRFIEELDVKPDGTR 266
Query: 678 VGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGS 737
V + QFSD E + +QTK++I AL Y N F + GS
Sbjct: 267 VAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSAGS 326
Query: 738 RIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 797
RI ++V Q L+LL AG+S D+ A++L + G++ F A AN +ELEQI +P+ +
Sbjct: 327 RIEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVLSPAFIL 386
Query: 798 LMDDFSSXXXXXXXXXXXXTTYVSGGVEEVPLAQPESKRDILFLFDGSANLVGQFPVVRD 857
+ G P++ ++D++FL DGS + FP+++D
Sbjct: 387 AAESLPKIGDLQSQIVSLLKAEQGSG----PVS---GEKDVVFLIDGSEGVRSGFPLLKD 439
Query: 858 FLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLG 917
F+ ++++ L+V P+ R+A+ QYSD + E + H + +++ ++R+ + G N G
Sbjct: 440 FVQRVVESLDVGPDRVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGTTPNTG 499
Query: 918 YALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKN 977
AL++ R I S GSRI +GV Q L++L A S D V GP+ LKQ G VP N
Sbjct: 500 AALEFVLRNILTSSTGSRIAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIGN 559
Query: 978 ADPAELEQIVLSPAFILAAESLPKIGDL------------HPQIVNLLKSVHNGAPAPVS 1025
AD +E++ I P F +A + ++G + ++ +L + A V
Sbjct: 560 ADISEMQTISFIPDFAVAIPTFRELGTIQRVISERVIQLNREELSSLKPILTPSTGAGVG 619
Query: 1026 GEKDVVFLLDGSEGVRSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSY 1085
+KDVVFL+DGS F ++ ++R+VE LD+G D RVAV+Q+S+ ++ EF LN++
Sbjct: 620 SKKDVVFLIDGSRNAGPEFQYIRTQIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAH 679
Query: 1086 MNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSG 1145
+K +V N VR+L GG G ALE+VL+NI GSRI EGVPQ L+++++ +
Sbjct: 680 FSKDEVQNTVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKYD 739
Query: 1146 DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERV 1205
D+V + +V +K+ G P+ I + D E+ IS P++ ++ TFR+L ++Q + +
Sbjct: 740 DEVDDSAVELKQFGVAPLTIA-RHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPI 798
Query: 1206 TQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDV 1264
T LT +++ ++ + PS D+VFLID S + P+ ++R + R+V L++
Sbjct: 799 TTLTSQQIHQILASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNI 858
Query: 1265 GFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIF 1324
G R+ V+QFS+D EF L H S+ V A++RLR KGG +N G ALE+V+RN+F
Sbjct: 859 GPSKVRIGVVQFSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLF 918
Query: 1325 KRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTIA-RNADQEELVKISL 1383
+ GSRIE+GVPQ LVL GKS D+V A + G+ I RN D+ +L I+
Sbjct: 919 VKSAGSRIEDGVPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITN 978
Query: 1384 SPEYVFSVSTFRELPSLEQKLLTPI--TTLTSEQIQKLLASTRYPPPAVESDAADIVFLI 1441
P VF+V FRELP++E++++ + T + L S P E ADIVFL+
Sbjct: 979 DPRLVFTVREFRELPNIEERVMLSFGPSGATPQPPGVDLPS----PSRPEKKKADIVFLL 1034
Query: 1442 DSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLD 1501
D S R D F + F S IV + +RVG+VQ+++D EF+L+ + ++ ++D
Sbjct: 1035 DGSINFRRDSFQEVLRFASVIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIID 1094
Query: 1502 AIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQ 1561
AI ++ +GG NT +E + RN FV AGSR++ VPQ ++ GGKS +D +
Sbjct: 1095 AINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDVRVPQIAFVITGGKSVEDAQDVSL 1154
Query: 1562 VIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEERIMNS 1612
+ G+ VG RNID E+ I ++ F V +EL + E ++ +
Sbjct: 1155 ALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLET 1205
Score = 681 bits (1737), Expect = 0.0
Identities = 424/1188 (35%), Positives = 648/1188 (53%), Gaps = 45/1188 (3%)
Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
DI+FL+DGS++ G NF I DF+ ++++L IG ++V V Q++D F L++Y+
Sbjct: 37 DIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVSPEFYLNSYTN 96
Query: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 361
K + AV+ + G G +LDFV N FT + G R EGVP++LVLI+ G S DE
Sbjct: 97 KRDAVTAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDE 156
Query: 362 IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVG 421
+ LK+ S+ + +G++AA EL+ IA D +LVF EFR LQ +LP +
Sbjct: 157 VSQPARELKRGSIMALAVGSKAADEDELKEIAFDSSLVFIPAEFRP-APLQ-NMLPSL-- 212
Query: 422 VAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDL 481
+ P +T E +KRDI+FL DGS + L F A+RDF+ + I+ L++ D
Sbjct: 213 -------MAPLRTLTGTTEGSKRDILFLFDGSVNV-LGQFPAVRDFLYRFIEELDVKPDG 264
Query: 482 IQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSA 541
+VA+AQ++D VR E F+ H TK E++ V+KMK G AL G ALD+ N+F SA
Sbjct: 265 TRVAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSA 324
Query: 542 GYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSL 601
G R + + + LVL+ G+S D ++ PA LK+ ++ F K A+ +ELE+I S
Sbjct: 325 GSRIEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVL--SP 382
Query: 602 VFIPAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDF 661
FI A + + +++ L+ G+ V S ++D++FL+DGS V ++ FP ++DF
Sbjct: 383 AFILAAESLPKIGDLQSQIVSLLKAEQGSGPV-SGEKDVVFLIDGSEGV-RSGFPLLKDF 440
Query: 662 VMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXXXXXXXXS 721
V +V SLD+G D +RV LVQ+SD EF LN++ + + +
Sbjct: 441 VQRVVESLDVGPDRVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGTTPNTGA 500
Query: 722 ALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQA 781
AL +V N T + GSRI E VPQLL++LTA S D + L + G + +G A
Sbjct: 501 ALEFVLRNILTSSTGSRIAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIGNA 560
Query: 782 NKAELEQIAFNPSLVYLMDDFSSXXXXXXXXXXXXTTYVSGGVEEV-PLAQPE------S 834
+ +E++ I+F P + F + + P+ P S
Sbjct: 561 DISEMQTISFIPDFAVAIPTFRELGTIQRVISERVIQLNREELSSLKPILTPSTGAGVGS 620
Query: 835 KRDILFLFDGSANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQ 894
K+D++FL DGS N +F +R + +I++ L++ + TR+AV Q+S+D K+E + H
Sbjct: 621 KKDVVFLIDGSRNAGPEFQYIRTQIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAHF 680
Query: 895 SKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSD 954
SK E+ N V+R++ K G + +G AL+Y + IF + GSRIE+GV QFLVL+ +G+ D
Sbjct: 681 SKDEVQNTVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKYDD 740
Query: 955 RVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLH-------- 1006
VD A LKQ GV P A++ D EL +I LSP ++ + + ++ L
Sbjct: 741 EVDDSAVELKQFGVAPLTI-ARHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPIT 799
Query: 1007 ----PQIVNLLKSVHNGAPAPVSGEKDVVFLLDGSEGVR-SGFPLLKEFVQRVVESLDVG 1061
QI +L S S D+VFL+D S+ V+ G +++FV R+V L++G
Sbjct: 800 TLTSQQIHQILASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIG 859
Query: 1062 QDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILV 1121
+VR+ VVQ+S+ PEFYL ++ ++ V+ A+R+L GG NTG ALEFV RN+ V
Sbjct: 860 PSKVRIGVVQFSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFV 919
Query: 1122 SSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFI 1181
SAGSRI +GVPQ L++ +S DDV + V+ G V +GIG N D T++QTI+
Sbjct: 920 KSAGSRIEDGVPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITND 979
Query: 1182 PDFAVAIPTFRQLGTVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKR--DVVFLID 1239
P + FR+L ++ ERV + QP LPSP K+ D+VFL+D
Sbjct: 980 PRLVFTVREFRELPNIE----ERVMLSFGPSGATPQPPGVDLPSPSRPEKKKADIVFLLD 1035
Query: 1240 GS-QSAGPEFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNA 1298
GS FQ V +VD + D+ RV ++Q++ DP EF L S+K ++ +A
Sbjct: 1036 GSINFRRDSFQEVLRFASVIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDA 1095
Query: 1299 VQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVE 1358
+ ++ KGGR N +E++ RN F GSR++ VPQ +I+ GKS ++ ++
Sbjct: 1096 INKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDVRVPQIAFVITGGKSVEDAQDVSLA 1155
Query: 1359 LKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLL 1405
L Q GV F + RN D EE+ KI+ + F V + +EL L + +L
Sbjct: 1156 LTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVL 1203
Score = 641 bits (1636), Expect = 0.0
Identities = 408/1247 (32%), Positives = 640/1247 (50%), Gaps = 67/1247 (5%)
Query: 1 MRKHRHLPLVAVFCLFLSGFPTTHAQQQQADVKNGAAADIIFLVDSSWTIGEEHFQLVRE 60
MRKHRHLPLVAVF L SG T AQQ N DI+FLVD S ++G +F +R+
Sbjct: 1 MRKHRHLPLVAVFSLLFSGIAMTRAQQHGVMEVN--KRDIVFLVDGSSSLGPSNFNAIRD 58
Query: 61 FLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRTKQEVLSHISNMSYIGGTN-QTG 119
F+ V++ L +G++ ++ Q+ EF LN+Y K++ ++ + M + G+ TG
Sbjct: 59 FVTRVIQRLEIGQDLVQVSVAQYADTVSPEFYLNSYTNKRDAVTAVRKMRALNGSALYTG 118
Query: 120 KGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGLALPSAELKSADVNVFAIGVED 179
L+++ + T +AG RA +GVP+++V++T G S D ++ P+ ELK + A+G +
Sbjct: 119 SSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGGKSLDEVSQPARELKRGSIMALAVGSKA 178
Query: 180 ADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLVSCVHSSVSPERAGDTETLKDITAQD 239
ADE LKEIA + +SL I ++ P TL T
Sbjct: 179 ADEDELKEIAFD------------SSLVFIPAEFRPAPLQNMLPSLMAPLRTLTGTTEGS 226
Query: 240 SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTY 299
DI+FL DGS N F + DFL +E+L + RV + QFSD+ R +
Sbjct: 227 KRDILFLFDGSVNVLG-QFPAVRDFLYRFIEELDVKPDGTRVAIAQFSDDVRLESRFSEH 285
Query: 300 STKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSS 359
TKA++L VK + G+ N+G ALD+ + N F R+ GSR+E+ V Q LVL+ AG SS
Sbjct: 286 QTKAEILNLVKKMKLKTGKALNLGYALDYALRNIFVRSAGSRIEDNVQQFLVLLVAGRSS 345
Query: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYI 419
D + +LKQ V F A+ A+ +EL+ I + GDLQ + I
Sbjct: 346 DAVAGPASSLKQRGVVPFIFQAKNANPSELEQIVLSPAFILAAESLPKIGDLQSQ----I 401
Query: 420 VGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQ 479
V + + P + ++D+VFL+DGS + + F ++DF+ +V++ L++G
Sbjct: 402 VSLLKAEQGSGPVS--------GEKDVVFLIDGSEGV-RSGFPLLKDFVQRVVESLDVGP 452
Query: 480 DLIQVAVAQYADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTS 539
D ++VA+ QY+D RPEFY N+H ++ VI+A+R++ L G+ TG+AL+FV N+ TS
Sbjct: 453 DRVRVALVQYSDRTRPEFYLNSHMDQQGVISAIRRLTLLGGTTPNTGAALEFVLRNILTS 512
Query: 540 SAGYRAAEGIPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAF-D 598
S G R AEG+P+LL+++T S D++ P+ LK+ + IG AD +E++ I+F
Sbjct: 513 STGSRIAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIGNADISEMQTISFIP 572
Query: 599 SSLVFIPAEFRAAPLQGMLP-----------GLLAPLRTLSGTPEVHSNKRDIIFLLDGS 647
V IP +Q ++ L P+ T S V S K+D++FL+DGS
Sbjct: 573 DFAVAIPTFRELGTIQRVISERVIQLNREELSSLKPILTPSTGAGVGS-KKDVVFLIDGS 631
Query: 648 ANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXX 707
N G F Y+R + +V LDIG D RV ++QFS+ EF LN + +K ++
Sbjct: 632 RNAG-PEFQYIRTQIERIVEYLDIGFDTTRVAVIQFSEDSKMEFPLNAHFSKDEVQNTVR 690
Query: 708 XXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALT 767
+AL YV N F GSRI E VPQ L+L+++G+ +D +A L
Sbjct: 691 RLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKYDDEVDDSAVELK 750
Query: 768 RAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSXXXXXXXXXXXXTTYVSGGVEEV 827
+ G+ + A ++ EL +I+ +P VY + F TT S + ++
Sbjct: 751 QFGVAPLTI-ARHTDQEELVKISLSPEYVYSVSTFRELPRLEQKLLTPITTLTSQQIHQI 809
Query: 828 -------PLAQPESKRDILFLFDGS-ANLVGQFPVVRDFLYKIIDELNVKPEGTRIAVAQ 879
P DI+FL D S A +RDF+ +I+ LN+ P RI V Q
Sbjct: 810 LASTRYPPSVVESDAADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGVVQ 869
Query: 880 YSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDG 939
+S+DV E H+S+ +L ++R++ K G LN G AL++ R +FVKSAGSRIEDG
Sbjct: 870 FSNDVFPEFYLKTHKSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDG 929
Query: 940 VLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESL 999
V Q LVL + G+S D V A + SG+V +N D +L+ I P +
Sbjct: 930 VPQHLVLFLGGKSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLVFTVREF 989
Query: 1000 PKIGDLHPQIVNLLKSVHNGA---------PAPVSGEK---DVVFLLDGSEGV-RSGFPL 1046
++ ++ ++ +L +GA P+P EK D+VFLLDGS R F
Sbjct: 990 RELPNIEERV--MLSFGPSGATPQPPGVDLPSPSRPEKKKADIVFLLDGSINFRRDSFQE 1047
Query: 1047 LKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTP 1106
+ F +V+++ D +RV +VQY+ EF+L + K+ +++A+ ++ GG
Sbjct: 1048 VLRFASVIVDTVYEDGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAINKVVYKGGRHA 1107
Query: 1107 NTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIG 1166
NT +E +LRN V AGSR+ VPQ+ V+T +S +D ++ S+ + + G +G
Sbjct: 1108 NTRVGIEHLLRNHFVPEAGSRLDVRVPQIAFVITGGKSVEDAQDVSLALTQKGVKVFAVG 1167
Query: 1167 IGNADITEMQTISFIPDFAVAIPTFRQLGTVQQVISERVTQLTREEL 1213
+ N D E+ I+ A + + ++L + + + E + E L
Sbjct: 1168 VRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLETLHDAMHETL 1214
Score = 254 bits (642), Expect = 1e-65
Identities = 120/179 (67%), Positives = 137/179 (76%)
Query: 2987 VVKMLREVQVFEITENSAKLHWERPEPPGPYFYDLTVTSAHDQSLVLKQNLTVTDRVIGG 3046
+ ++ REVQV E+TENSA+LHWERPEP +FYDLTVTSAHDQSLVL+QNLTVTDRVIGG
Sbjct: 2477 LARVSREVQVSEVTENSARLHWERPEPSSSFFYDLTVTSAHDQSLVLRQNLTVTDRVIGG 2536
Query: 3047 LLAGQTYHVAVVCYLRSQVRATYHGSFXXXXXXXXXXXXXXXXXXXXINLMVSTEPLALT 3106
LLAGQ YHV VV YL+SQVRA Y GSF INLMV+TEPL LT
Sbjct: 2537 LLAGQLYHVVVVSYLQSQVRAIYQGSFNTKKTQPPPLQAAHRASSSTINLMVNTEPLFLT 2596
Query: 3107 ETDICKLPKDEGTCRDFILKWYYDPNTKSCARFWYGGCGGNENKFGSQKECEKVCAPVL 3165
+TDICKL +D GTC DF L W+YD +KSC RFWYGGCGGNEN+F SQ+ECEK+C+P L
Sbjct: 2597 KTDICKLSRDAGTCVDFKLLWHYDLESKSCKRFWYGGCGGNENRFHSQEECEKMCSPEL 2655
Score = 194 bits (487), Expect = 2e-47
Identities = 156/559 (27%), Positives = 269/559 (47%), Gaps = 26/559 (4%)
Query: 37 AADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTY 96
AADI+FL+DSS + + +R+F+ +V+ L +G + +VQF+ + EF L T+
Sbjct: 824 AADIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIGPSKVRIGVVQFSNDVFPEFYLKTH 883
Query: 97 RTKQEVLSHISNMSYIGGTN-QTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSK 155
+++ VL I + + GG+ TG+ LE++ ++ K+AGSR DGVPQ +V+ G S+
Sbjct: 884 KSQSSVLEAIRRLRFKGGSPLNTGRALEFVARNLFVKSAGSRIEDGVPQHLVLFLGGKSQ 943
Query: 156 DGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGN-LV 214
D +A + + S+ + IG + D L+ I ++P +F + F L +I ++
Sbjct: 944 DDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDP--RLVFTVREFRELPNIEERVML 1001
Query: 215 SCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPI 274
S S +P+ G + ADI+FL+DGS N +F +L F +++ +
Sbjct: 1002 SFGPSGATPQPPGVDLPSPSRPEKKKADIVFLLDGSINFRRDSFQEVLRFASVIVDTVYE 1061
Query: 275 GTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHF 334
IRVG+VQ++ +P F L +STK Q++ A+ + + GG AN + ++ ++ NHF
Sbjct: 1062 DGDSIRVGLVQYNSDPTDEFFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHF 1121
Query: 335 TRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIAT 394
GSR++ VPQ+ +I+ G S ++ + +AL Q V F +G + E+ IA+
Sbjct: 1122 VPEAGSRLDVRVPQIAFVITGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIAS 1181
Query: 395 DDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGS- 453
+ F V + +L E +L + H L P VT V + +++ DGS
Sbjct: 1182 NSATAFRVGSVQELSELSETVLETLHDA--MHETLCPG--VTDVSKACNLEVILGFDGSR 1237
Query: 454 ------SALGLANFNAIRDFIAKVIQRLEI-GQDLIQVAVAQYADTVR-PEFYFNTHPTK 505
S GL + I IQR+ G L V V+ A+T P F+ +
Sbjct: 1238 DQNVFVSQKGLESKVDIILNRTSQIQRISCSGNQLPTVRVSVMANTPSGPVEAFDFAEYQ 1297
Query: 506 REVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD-- 563
E+ R M+ L T L +N SS K+++ T G D
Sbjct: 1298 PELFEKFRNMRSQRPYVL-TADTLKLYQNKFRQSS------PDTVKVVIHFTDGADGDMA 1350
Query: 564 EISQPAQELKRSSIMAFAI 582
++ + ++EL+++ A +
Sbjct: 1351 DLYRASEELRQAGAQALIL 1369
Score = 96.7 bits (237), Expect = 3e-18
Identities = 52/164 (31%), Positives = 87/164 (52%)
Query: 1634 EKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFL 1693
E K DIVFL+DGS + +F + FV+ ++ + D +QV + QY + EF+L
Sbjct: 32 EVNKRDIVFLVDGSSSLGPSNFNAIRDFVTRVIQRLEIGQDLVQVSVAQYADTVSPEFYL 91
Query: 1694 KDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGG 1753
++ KR + A+ K+ G T L+ +R N F AG R + VP++ +ITGG
Sbjct: 92 NSYTNKRDAVTAVRKMRALNGSALYTGSSLDFVRNNLFTSSAGHRAAEGVPKLLVLITGG 151
Query: 1754 KSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAF 1797
KS+++ + L + + AVG + D +E+ +IA +S+ F
Sbjct: 152 KSLDEVSQPARELKRGSIMALAVGSKAADEDELKEIAFDSSLVF 195
Score = 72.6 bits (175), Expect = 6e-11
Identities = 86/403 (21%), Positives = 171/403 (42%), Gaps = 51/403 (12%)
Query: 1233 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKAEFLLN 1287
++ F +D S+ + F +R ++ +V L + RVAV+ ++++ E
Sbjct: 1792 ELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 1851
Query: 1288 AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLI--- 1343
+ K + +++Q L+ +Q ++ A+ +V+RN FKR + G P V +
Sbjct: 1852 SSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTFKR-----VRSGFPMRKVAVFFS 1906
Query: 1344 -SSGKSDDEVVVPAVELKQFGVAPFTIARNADQEELVKISLSPEYV---FSVSTFRELPS 1399
++ ++ ++L G+ P + D++ + + ++ V + R+L
Sbjct: 1907 NKPTRASPQLREAVLKLSDAGITPLFLTSQEDRQLINALQINNTAVGHALVLPARRDLTD 1966
Query: 1400 LEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAA------DIVFLIDSSEGVRPDGFA 1453
+ +LT L I + P + AA D+ F++DSSE F
Sbjct: 1967 FLKNVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFN 2026
Query: 1454 HIRDFVSRIVRRLNIGPSK------VRVGVVQFSN----------DVFPEFYLKTYRSQA 1497
++ ++ ++R+L++ P RV VVQ S V EF L Y ++
Sbjct: 2027 EMKKYIGYVIRQLDLSPDPKASQHFARVAVVQQSTYESVDNASVPPVKVEFSLTDYGAKE 2086
Query: 1498 PVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ---- 1553
+LD + R + + G A+E+ N+F + R + +VL+L G Q
Sbjct: 2087 KLLDFLSRRMTQLQGTMGLGNAIEYTIENIFESAPNPR----DLKIMVLMLTGDMQRQQL 2142
Query: 1554 DDVSRFAQVIRSSG--IVSLGVGDRNIDRTELQTITNDPRLVF 1594
++ R + G +V LG+G R ++ E+ + ++P VF
Sbjct: 2143 EEAQRAILQAKCKGYFLVVLGIG-RKVNIKEVYSFASEPNDVF 2184
Score = 72.2 bits (174), Expect = 8e-11
Identities = 95/409 (23%), Positives = 172/409 (41%), Gaps = 63/409 (15%)
Query: 828 PLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 882
PL P ++ F D S + F +R+ L I+ +L + P G R+AV Y++
Sbjct: 1783 PLECPVLPTELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNN 1842
Query: 883 DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 941
+V E RF + K +L+ ++ +++ T K +L A+ + R F R+ G
Sbjct: 1843 EVTTEIRFASSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTF-----KRVRSGFP 1897
Query: 942 QFLVLLVAG----RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 997
V + R+S ++ L +G+ P +F D + + ++ + A
Sbjct: 1898 MRKVAVFFSNKPTRASPQLREAVLKLSDAGITP-LFLTSQEDRQLINALQINNTAVGHAL 1956
Query: 998 SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 1036
LP DL + N+L S + A + D+ F+LD
Sbjct: 1957 VLPARRDLTDFLKNVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDLAFILDS 2016
Query: 1037 SEGVR-SGFPLLKEFVQRVVESLDVGQDR------VRVAVVQYS----------DRTRPE 1079
SE F +K+++ V+ LD+ D RVAVVQ S + E
Sbjct: 2017 SEATTLFQFNEMKKYIGYVIRQLDLSPDPKASQHFARVAVVQQSTYESVDNASVPPVKVE 2076
Query: 1080 FYLNSYMNKQDVVNAV-RQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIV 1138
F L Y K+ +++ + R++T L G T G A+E+ + NI S+ R + ++++
Sbjct: 2077 FSLTDYGAKEKLLDFLSRRMTQLQG-TMGLGNAIEYTIENIFESAPNPR---DLKIMVLM 2132
Query: 1139 LTAD---RSGDDVRNPSVVVKRGGAVPIGIGIG-NADITEMQTISFIPD 1183
LT D + ++ + + K G + +GIG +I E+ + + P+
Sbjct: 2133 LTGDMQRQQLEEAQRAILQAKCKGYFLVVLGIGRKVNIKEVYSFASEPN 2181
Score = 67.5 bits (162), Expect = 2e-09
Identities = 99/418 (23%), Positives = 180/418 (42%), Gaps = 50/418 (11%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D+S+ V D +RD V IV L I P+ R+ VV ++N+V E
Sbjct: 826 DIVFLIDSSDAVKPDGIAHIRDFVSRIVRRLNIG----PSKVRIGVVQFSNDVFPEFYLK 881
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF-----KRVRNGFLMRKVAVFFS 2516
K +S +L+ I+ L+ S + A+ FVARN F R+ +G + + + +F
Sbjct: 882 THKSQSSVLEAIRRLRFKGGSPLNT-GRALEFVARNLFVKSAGSRIEDG-VPQHLVLFLG 939
Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFL-TRQEDRQLINALQINNTAVGHALVLPAGRDLT 2575
++ + +S +GI L + R DR + + + V + R+L
Sbjct: 940 G---KSQDDVARHAQVISSSGIVSLGIGDRNIDRTDLQTITNDPRLV---FTVREFRELP 993
Query: 2576 DFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQF 2635
+ E V+ P S PS +++ A D+ F+LD + F
Sbjct: 994 NIEERVMLSFGPSGATPQPPGVDLPS--PSRPEKKKA------DIVFLLDGSINFRRDSF 1045
Query: 2636 NEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSK 2695
E+ ++ + +V + D RV +VQ+ S+ D EF L D+ +K
Sbjct: 1046 QEVLRFASVIVDTVYEDGDS------IRVGLVQY-NSDPTD---------EFFLRDFSTK 1089
Query: 2696 EKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR-DLKI--VVLMLTGEVPEQQL 2752
+++D +++ + + IE+ + N F R D+++ + ++TG + +
Sbjct: 1090 RQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDVRVPQIAFVITG---GKSV 1146
Query: 2753 EEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVF-FKLVDKSTELNEEPL 2809
E+AQ V L KG +G+ R ++ +EV AS F V + +EL+E L
Sbjct: 1147 EDAQDVSLALTQKGVKVFAVGV-RNIDSEEVGKIASNSATAFRVGSVQELSELSETVL 1203
Score = 67.1 bits (161), Expect = 3e-09
Identities = 89/417 (21%), Positives = 172/417 (40%), Gaps = 56/417 (13%)
Query: 2383 IKDKCPCCYGPLECPVFPTE-----LAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAES 2437
+++ P PL TE + F D S V F +RD + + L +
Sbjct: 205 LQNMLPSLMAPLRTLTGTTEGSKRDILFLFDGSVNV-LGQFPAVRDFLYRFIEELDVK-- 261
Query: 2438 NCPTGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARN 2497
P G RVA+ ++++V E RF++ + K+ +L+ +K +++ T K +L A+ + RN
Sbjct: 262 --PDGTRVAIAQFSDDVRLESRFSEHQTKAEILNLVKKMKLK-TGKALNLGYALDYALRN 318
Query: 2498 TFKRVRNGFLMRKVAVFF-SNTPTRASPQLREAVLKLSDAGITP-LFLTRQEDRQLINAL 2555
F R + V F R+S + L G+ P +F + + + +
Sbjct: 319 IFVRSAGSRIEDNVQQFLVLLVAGRSSDAVAGPASSLKQRGVVPFIFQAKNANPSELEQI 378
Query: 2556 QINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSD 2615
++ + A LP DL + ++L ++ +
Sbjct: 379 VLSPAFILAAESLPKIGDLQSQIVSLLKA-----------------------EQGSGPVS 415
Query: 2616 VDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESV 2675
+ D+ F++D +E F +K ++ +V LD+ PD RVA+VQ++
Sbjct: 416 GEKDVVFLIDGSEGVR-SGFPLLKDFVQRVVESLDVGPDR------VRVALVQYSDR--- 465
Query: 2676 DNASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRA-LGSAIEYTIENVFESAPNPR 2734
+ EF L + ++ ++ + R +T L GT G+A+E+ + N+ S+ R
Sbjct: 466 -------TRPEFYLNSHMDQQGVISAIRR-LTLLGGTTPNTGAALEFVLRNILTSSTGSR 517
Query: 2735 DLKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
+ V +L E ++ + + K G + +GIG +I E+ T + P+
Sbjct: 518 IAEGVPQLLIVLTAEPSGDDVRGPSVVLKQGGAVPIGIGIG-NADISEMQTISFIPD 573
Score = 60.5 bits (144), Expect = 3e-07
Identities = 86/379 (22%), Positives = 160/379 (41%), Gaps = 59/379 (15%)
Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI----RVGVVQFSDEPRTMFSLD 297
++ F +D S F+ + + L+ ++ L I RV VV +++E T
Sbjct: 1792 ELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 1851
Query: 298 TYSTKAQVLGAVKALGFA-GGELANIGLALDFVVENHFTRAGGSRVEEGVP--QVLVLIS 354
+ K+ +L +++ L A + ++ A+ FV N F RV G P +V V S
Sbjct: 1852 SSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTF-----KRVRSGFPMRKVAVFFS 1906
Query: 355 AGPS--SDEIRYGVVALKQASVFSFGLGAQA----ASRAELQHIATDDNLVFTVPEFRSF 408
P+ S ++R V+ L A + L +Q + ++ + A LV +P R
Sbjct: 1907 NKPTRASPQLREAVLKLSDAGITPLFLTSQEDRQLINALQINNTAVGHALV--LPARRDL 1964
Query: 409 GDLQEKLLPYIV-----------GVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGSSALG 457
D + +L V G + +++ D+ F++D S A
Sbjct: 1965 TDFLKNVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDI---DLAFILDSSEATT 2021
Query: 458 LANFNAIRDFIAKVIQRLEIGQD------LIQVAVAQYAD----------TVRPEFYFNT 501
L FN ++ +I VI++L++ D +VAV Q + V+ EF
Sbjct: 2022 LFQFNEMKKYIGYVIRQLDLSPDPKASQHFARVAVVQQSTYESVDNASVPPVKVEFSLTD 2081
Query: 502 HPTKREVITAV-RKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGK 560
+ K +++ + R+M L G+ + G+A+++ N+F S+ R K++VL+ G
Sbjct: 2082 YGAKEKLLDFLSRRMTQLQGT-MGLGNAIEYTIENIFESAPNPRDL----KIMVLMLTG- 2135
Query: 561 SLDEISQPAQELKRSSIMA 579
D Q +E +R+ + A
Sbjct: 2136 --DMQRQQLEEAQRAILQA 2152
Score = 58.9 bits (140), Expect = 8e-07
Identities = 38/99 (38%), Positives = 45/99 (45%), Gaps = 31/99 (31%)
Query: 2080 GTQGFQGCPGQ---RGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRR 2136
GT+G QG PG G+ G +GFPG + G G PG R
Sbjct: 1615 GTRGSQGPPGPIGPPGLIGEQGFPGPRG---------------------GGGTAGAPGER 1653
Query: 2137 GDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
G GP G KGE G+ G +G GN RGP+GETGD
Sbjct: 1654 GRTGPLGRKGEPGEPGPKGSIGN-------RGPRGETGD 1685
Score = 55.0 bits (130), Expect = 1e-05
Identities = 86/402 (21%), Positives = 166/402 (40%), Gaps = 50/402 (12%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F +D SEGV F ++D V +V L + P RVA+V Y++ E
Sbjct: 419 DVVFLIDGSEGVRSG-FPLLKDFVQRVVESLDVG----PDRVRVALVQYSDRTRPEFYLN 473
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARN-----TFKRVRNGFLMRKVAVFFS 2516
+ ++ I+ L + L + A+ FV RN T R+ G + +
Sbjct: 474 SHMDQQGVISAIRRLTL-LGGTTPNTGAALEFVLRNILTSSTGSRIAEGVPQLLIVL--- 529
Query: 2517 NTPTRASPQLREAVLKLSDAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTD 2576
T + +R + L G P+ + I+ +Q + A+ +P R+L
Sbjct: 530 -TAEPSGDDVRGPSVVLKQGGAVPIGIGIGNAD--ISEMQTISFIPDFAVAIPTFRELGT 586
Query: 2577 FLENVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFN 2636
++ V++ V + + + S S +P AG D+ F++D + +F
Sbjct: 587 -IQRVISERV-IQLNREELS----SLKPILTPSTGAGVGSKKDVVFLIDGSRNAGP-EFQ 639
Query: 2637 EMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNASMPPVKVEFSLTDYGSKE 2696
++ I +V LD+ D RVAV+Q + K+EF L + SK+
Sbjct: 640 YIRTQIERIVEYLDIGFDT------TRVAVIQFSEDS----------KMEFPLNAHFSKD 683
Query: 2697 KLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPR----DLKIVVLMLTGEVPEQQL 2752
++ + + R + +G+A+EY ++N+F+ R + +VL+ +G+ ++
Sbjct: 684 EVQNTVRRLRPKGGSQVYIGNALEYVLKNIFQRPLGSRIEEGVPQFLVLISSGKYDDEVD 743
Query: 2753 EEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPNDVF 2794
+ A + K + L I R + +E+ + P V+
Sbjct: 744 DSA------VELKQFGVAPLTIARHTDQEELVKISLSPEYVY 779
Score = 51.9 bits (122), Expect = 1e-04
Identities = 33/90 (36%), Positives = 37/90 (40%), Gaps = 19/90 (21%)
Query: 2086 GCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDKGPRGEK 2145
G G+RG KG RGFPG G G PG +G +G RG
Sbjct: 1692 GSEGRRGKKGERGFPGYPGPKGTPG---------------EPGADGPPGPKGIRGRRGNS 1736
Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
G G G +GDPG PG G KG GD
Sbjct: 1737 GPPGATGQKGDPGYPGPS----GHKGNRGD 1762
Score = 50.4 bits (118), Expect = 3e-04
Identities = 90/402 (22%), Positives = 163/402 (40%), Gaps = 49/402 (12%)
Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGEND----FHFALVQFNGNPHTEFLLN 94
++ F +D+S + ++ F +RE L +V L + E++ A+V +N TE
Sbjct: 1792 ELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 1851
Query: 95 TYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP--QVIVVLTDG 152
+ + K +L I N+ + Q + LE M S + + R G P +V V ++
Sbjct: 1852 SSKKKSALLDSIQNLQVALTSKQ--QSLETAM-SFVARNTFKRVRSGFPMRKVAVFFSNK 1908
Query: 153 HSKDGLALPSAELKSADVNV---FAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDI 209
++ L A LK +D + F ED +I + + H L L D
Sbjct: 1909 PTRASPQLREAVLKLSDAGITPLFLTSQEDRQLINALQINNTAVG-HALVLPARRDLTDF 1967
Query: 210 VGNLVSCVH-----SSVSPERAGDT--ETLKDITAQDS---ADIIFLIDGSNNTGSVNFA 259
+ N+++C H ++ P + + +D A S D+ F++D S T F
Sbjct: 1968 LKNVLTC-HVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFN 2026
Query: 260 VILDFLVNLLEKL-----PIGTQQI-RVGVVQFS----------DEPRTMFSLDTYSTKA 303
+ ++ ++ +L P +Q RV VVQ S + FSL Y K
Sbjct: 2027 EMKKYIGYVIRQLDLSPDPKASQHFARVAVVQQSTYESVDNASVPPVKVEFSLTDYGAKE 2086
Query: 304 QVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSS---- 359
++L + +G A+++ +EN F A R +++VL+ G
Sbjct: 2087 KLLDFLSRRMTQLQGTMGLGNAIEYTIENIFESAPNPR----DLKIMVLMLTGDMQRQQL 2142
Query: 360 DEIRYGVVALKQASVFSFGLG-AQAASRAELQHIATDDNLVF 400
+E + ++ K F LG + + E+ A++ N VF
Sbjct: 2143 EEAQRAILQAKCKGYFLVVLGIGRKVNIKEVYSFASEPNDVF 2184
Score = 46.9 bits (109), Expect = 0.004
Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 3/44 (6%)
Query: 2315 FPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
+ GYPG +G+PGE PG+NGT G +G G+RG G G G+K
Sbjct: 1450 YRGYPGDEGDPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEK 1493
Score = 44.9 bits (104), Expect = 0.014
Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 25/96 (26%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
G G G PG+ G+ GS G PG+ SG +G G +G++
Sbjct: 1564 GDIGPMGLPGRDGIPGSPGDPGKDG---------------------GSGRRGPAGAKGNR 1602
Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
G G+ G G+ G RG G PG GP G G+
Sbjct: 1603 GGPGQPGFEGEQGTRGSQGPPG----PIGPPGLIGE 1634
Score = 44.5 bits (103), Expect = 0.018
Identities = 17/39 (43%), Positives = 25/39 (63%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G G +G PG+PG G G +G +G G GPPG++G++
Sbjct: 1597 GAKGNRGGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQ 1635
Score = 44.5 bits (103), Expect = 0.018
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G PG G+PG+ G +G GP G +G RG G PG G++
Sbjct: 1576 GIPGSPGDPGKDGGSGRRGPAGAKGNRGGPGQPGFEGEQ 1614
Score = 43.0 bits (99), Expect = 0.053
Identities = 19/42 (45%), Positives = 24/42 (56%), Gaps = 3/42 (7%)
Query: 2317 GYPGPKGN---PGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G+PGP+G G PG G TGP G +G G GP G +G +
Sbjct: 1636 GFPGPRGGGGTAGAPGERGRTGPLGRKGEPGEPGPKGSIGNR 1677
Score = 40.2 bits (92), Expect = 0.35
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G G G G+ GL G++G KG GRRG+ GP G G++
Sbjct: 1500 GLDGLDGEEGDKGLPGSSGEKGSPGRRGDKGPKGDKGER 1538
Score = 39.9 bits (91), Expect = 0.46
Identities = 18/39 (46%), Positives = 25/39 (63%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G+PG KG GE GL+G G +G +G G+SG G G++
Sbjct: 1488 GFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGRR 1526
Score = 39.5 bits (90), Expect = 0.60
Identities = 18/37 (48%), Positives = 20/37 (53%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353
G PG G G PG G GPKG +G RG+ G G G
Sbjct: 1512 GLPGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPG 1548
Score = 37.5 bits (85), Expect = 2.3
Identities = 19/39 (48%), Positives = 21/39 (53%)
Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
PG G KG+PG G G G KG RG G G PG G+
Sbjct: 1514 PGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPGDSGR 1552
Score = 37.5 bits (85), Expect = 2.3
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 6/74 (8%)
Query: 2080 GTQGFQGCPGQRGVKG---SRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRR 2136
G++G +G G+RG G +G PGE ++G+KG+PG
Sbjct: 1692 GSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGATGQKGDPGY- 1750
Query: 2137 GDKGPRGEKGERGD 2150
GP G KG RGD
Sbjct: 1751 --PGPSGHKGNRGD 1762
Score = 36.0 bits (81), Expect = 6.8
Identities = 17/39 (43%), Positives = 21/39 (53%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G G +G PGE G G G G+ G G+ G PG G+K
Sbjct: 1482 GVKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEK 1520
>pir||S32605 collagen alpha 3(VI) chain - mouse (fragment)
emb|CAA79156.1| (Z18279) collagen alpha 3 chain type VI [Mus musculus]
Length = 959
Score = 704 bits (1796), Expect = 0.0
Identities = 354/486 (72%), Positives = 381/486 (77%)
Query: 1691 FFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVI 1750
FFL+DFSTKRQIIDAINKVVYKGGRHANT+VG+EHL NHFVPEAGSRLD+RVPQIAFVI
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 1751 TGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNXXXXXXXXX 1810
TGGKSVEDAQDVSLALTQ+GVKVFAVGVRNIDSEEVGKIASNSATAFRVG+
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSE 120
Query: 1811 XXXXXXHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNRIS 1870
HDAMHETLCPGVTD +KACNL+VILGFDGSRDQNVFV+QKG ESKVD ILNRIS
Sbjct: 121 TVLETLHDAMHETLCPGVTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDIILNRIS 180
Query: 1871 QMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTEDTL 1930
Q+ R+SCSG + PTVRVSV+ANTPSGPVEAFDF EYQPE+ EKFRNMRSQ PYVLT DTL
Sbjct: 181 QIQRISCSGNQLPTVRVSVMANTPSGPVEAFDFAEYQPELFEKFRNMRSQRPYVLTADTL 240
Query: 1931 KVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNLER 1990
K+Y NKFRQSSPD+VKVVIHFTDGADGD+ADL+RASE LRQ G +ALILVGLERV NLER
Sbjct: 241 KLYQNKFRQSSPDTVKVVIHFTDGADGDMADLYRASEELRQAGAQALILVGLERVANLER 300
Query: 1991 LMHLEFGRGFMXXXXXXXXXXXXXXXXAEQLDNIAEKACCGVPCKCSGQRGDRXXXXXXX 2050
LMHLEFGRGFM AEQLDNIAEKACCGVPCKCSG+RGDR
Sbjct: 301 LMHLEFGRGFMYDRPLRLNQLDLDYELAEQLDNIAEKACCGVPCKCSGERGDRGPIGSIG 360
Query: 2051 XXXXXXXXXXXXXXXXXXXXXXXXXXXVNGTQGFQGCPGQRGVKGSRGFPGEKXXXXXXX 2110
VNGTQGFQGCPGQRGVKGSRGFPGEK
Sbjct: 361 PKGISGEDGYRGYPGDEGDPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEKGELGEIG 420
Query: 2111 XXXXXXXXXXXXXXXSSGEKGNPGRRGDKGPRGEKGERGDVGIRGDPGNPGQDSQERGPK 2170
SSGEKG+PGRRGDKGP+G+KGERGDVGIRGDPG+ G+DSQ+RGPK
Sbjct: 421 LDGLDGEEGDKGLPGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPGDSGRDSQQRGPK 480
Query: 2171 GETGDL 2176
GETGD+
Sbjct: 481 GETGDI 486
Score = 585 bits (1491), Expect = e-165
Identities = 289/355 (81%), Positives = 302/355 (84%)
Query: 2295 DDGRDXXXXXXXXXXXXXXXFPGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
DDGRD FPGYPGPKG PGEPG +G GPKGIRGRRGNSGPPG GQ
Sbjct: 605 DDGRDGVGSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGATGQ 664
Query: 2355 KXXXXXXXXXXXXXXXXDSIDQCALIQSIKDKCPCCYGPLECPVFPTELAFALDTSEGVN 2414
K DS+DQCALIQSI+DKCPCCYGPLECPV PTELAFALDTSEGV
Sbjct: 665 KGDPGYPGPSGHKGNRGDSVDQCALIQSIRDKCPCCYGPLECPVLPTELAFALDTSEGVT 724
Query: 2415 QDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFADSKRKSVLLDKIK 2474
QDTF RMR+V+L IV LTIAESNCP GARVAVVTYNNEVTTEIRFA SK+KS LLD I+
Sbjct: 725 QDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFASSKKKSALLDSIQ 784
Query: 2475 NLQVALTSKQQSLETAMSFVARNTFKRVRNGFLMRKVAVFFSNTPTRASPQLREAVLKLS 2534
NLQVALTSKQQSLETAMSFVARNTFKRVR+GF MRKVAVFFSN PTRASPQLREAVLKLS
Sbjct: 785 NLQVALTSKQQSLETAMSFVARNTFKRVRSGFPMRKVAVFFSNKPTRASPQLREAVLKLS 844
Query: 2535 DAGITPLFLTRQEDRQLINALQINNTAVGHALVLPAGRDLTDFLENVLTCHVCLDICNID 2594
DAGITPLFLT QEDRQLINALQINNTAVGHALVLPA RDLTDFL+NVLTCHVCLDICNID
Sbjct: 845 DAGITPLFLTSQEDRQLINALQINNTAVGHALVLPARRDLTDFLKNVLTCHVCLDICNID 904
Query: 2595 PSCGFGSWRPSFRDRRAAGSDVDIDMAFILDSAETTTLFQFNEMKKYIAYLVRQL 2649
PSCGFGSWRPSFRDRRAAGSDVDID+AFILDS+E TTLFQFNEMKKYI Y++RQL
Sbjct: 905 PSCGFGSWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFNEMKKYIGYVIRQL 959
Score = 81.9 bits (199), Expect = 1e-13
Identities = 40/125 (32%), Positives = 69/125 (55%)
Query: 1488 FYLKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLV 1547
F+L+ + ++ ++DAI ++ +GG NT +E + RN FV AGSR+++ VPQ ++
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 1548 LGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEE 1607
GGKS +D + + G+ VG RNID E+ I ++ F V +EL + E
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSE 120
Query: 1608 RIMNS 1612
++ +
Sbjct: 121 TVLET 125
Score = 75.7 bits (183), Expect = 7e-12
Identities = 79/301 (26%), Positives = 137/301 (45%), Gaps = 24/301 (7%)
Query: 294 FSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLI 353
F L +STK Q++ A+ + + GG AN + ++ ++ NHF GSR++E VPQ+ +I
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 354 SAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQE 413
+ G S ++ + +AL Q V F +G + E+ IA++ F V + +L E
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSE 120
Query: 414 KLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLVDGS-------SALGL-ANFNAIR 465
+L + H L P VT V + +++ DGS S GL + + I
Sbjct: 121 TVLETLHDA--MHETLCPG--VTDVSKACNLEVILGFDGSRDQNVFVSQKGLESKVDIIL 176
Query: 466 DFIAKVIQRLEI-GQDLIQVAVAQYADTVR-PEFYFNTHPTKREVITAVRKMKPLDGSAL 523
+ I++ IQR+ G L V V+ A+T P F+ + E+ R M+ L
Sbjct: 177 NRISQ-IQRISCSGNQLPTVRVSVMANTPSGPVEAFDFAEYQPELFEKFRNMRSQRPYVL 235
Query: 524 YTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLD--EISQPAQELKRSSIMAFA 581
T L +N SS K+++ T G D ++ + ++EL+++ A
Sbjct: 236 -TADTLKLYQNKFRQSS------PDTVKVVIHFTDGADGDMADLYRASEELRQAGAQALI 288
Query: 582 I 582
+
Sbjct: 289 L 289
Score = 73.7 bits (178), Expect = 3e-11
Identities = 43/123 (34%), Positives = 69/123 (55%), Gaps = 1/123 (0%)
Query: 1284 FLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLI 1343
F L S+K ++ +A+ ++ KGGR N +E++ RN F GSR++E VPQ +I
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 1344 SSGKSDDEVVVPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQ 1402
+ GKS ++ ++ L Q GV F + RN D EE+ KI+ + F V + +EL L +
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSE 120
Query: 1403 KLL 1405
+L
Sbjct: 121 TVL 123
Score = 73.4 bits (177), Expect = 4e-11
Identities = 37/134 (27%), Positives = 70/134 (51%)
Query: 1080 FYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVL 1139
F+L + K+ +++A+ ++ GG NT +E +LRN V AGSR+ E VPQ+ V+
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 1140 TADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQ 1199
T +S +D ++ S+ + + G +G+ N D E+ I+ A + + ++L + +
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSE 120
Query: 1200 VISERVTQLTREEL 1213
+ E + E L
Sbjct: 121 TVLETLHDAMHETL 134
Score = 68.7 bits (165), Expect = 1e-09
Identities = 44/165 (26%), Positives = 84/165 (50%), Gaps = 10/165 (6%)
Query: 91 FLLNTYRTKQEVLSHISNMSYIGGTN-QTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVL 149
F L + TK++++ I+ + Y GG + T G+E+++++H AGSR + VPQ+ V+
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 150 TDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLN-MHMFNLENFTSLHD 208
T G S + S L V VFA+GV + D + +IAS + +++ + L +
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSE 120
Query: 209 -IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNN 252
++ L +H ++ P + D++ + ++I DGS +
Sbjct: 121 TVLETLHDAMHETLCP-------GVTDVSKACNLEVILGFDGSRD 158
Score = 62.8 bits (150), Expect = 6e-08
Identities = 32/107 (29%), Positives = 56/107 (51%)
Query: 497 FYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLI 556
F+ TKR++I A+ K+ G T ++ + N F AG R E +P++ +I
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 557 TGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF 603
TGGKS+++ + L + + FA+G + D E+ +IA +S+ F
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAF 107
Score = 58.9 bits (140), Expect = 8e-07
Identities = 38/96 (39%), Positives = 46/96 (47%), Gaps = 7/96 (7%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
G +G +G PGQ G +G +G G + G G PG RG
Sbjct: 517 GAKGNRGGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQXXXGPRGGGGTAGAPGERGRT 576
Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
GP G KGE G+ G +G GN RGP+GETGD
Sbjct: 577 GPLGRKGEPGEPGPKGSIGN-------RGPRGETGD 605
Score = 55.8 bits (132), Expect = 7e-06
Identities = 38/117 (32%), Positives = 61/117 (51%), Gaps = 10/117 (8%)
Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIG----PSKVRVGVVQFSNDVFPEFYLK 1491
++ F +D+SEGV D F+ +R+ + IV L I P RV VV ++N+V E
Sbjct: 712 ELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 771
Query: 1492 TYRSQAPVLDAIRRLRLRGGSPLNT-GKALEFVARNLFVKSAGSRIEDGVPQHLVLV 1547
+ + ++ +LD+I+ L++ S + A+ FVARN F R+ G P V V
Sbjct: 772 SSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTF-----KRVRSGFPMRKVAV 823
Score = 55.0 bits (130), Expect = 1e-05
Identities = 29/107 (27%), Positives = 47/107 (43%)
Query: 691 FSLNTYQTKSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLL 750
F L + TK I + ++ NHF GSR+ E VPQ+ ++
Sbjct: 1 FFLRDFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVI 60
Query: 751 TAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVY 797
T G+S + + ALT+ G+ F VG + E+ +IA N + +
Sbjct: 61 TGGKSVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAF 107
Score = 53.5 bits (126), Expect = 4e-05
Identities = 36/102 (35%), Positives = 46/102 (44%), Gaps = 7/102 (6%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
G G G G++G +GS+G PG + GE+G G G K
Sbjct: 523 GGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQXXXGPRGGGGTAGAPGERGRTGPLGRK 582
Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQE-------RGPKGETG 2174
G GE G +G +G RG G G D ++ RG KGE G
Sbjct: 583 GEPGEPGPKGSIGNRGPRGETGDDGRDGVGSEGRRGKKGERG 624
Score = 51.9 bits (122), Expect = 1e-04
Identities = 33/90 (36%), Positives = 37/90 (40%), Gaps = 19/90 (21%)
Query: 2086 GCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDKGPRGEK 2145
G G+RG KG RGFPG G G PG +G +G RG
Sbjct: 612 GSEGRRGKKGERGFPGYPGPKGTPG---------------EPGADGPPGPKGIRGRRGNS 656
Query: 2146 GERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
G G G +GDPG PG G KG GD
Sbjct: 657 GPPGATGQKGDPGYPGPS----GHKGNRGD 682
Score = 51.5 bits (121), Expect = 1e-04
Identities = 29/122 (23%), Positives = 59/122 (47%)
Query: 892 EHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGR 951
+ +K +I++ + ++ K G+ N +++ R FV AGSR+++ V Q ++ G+
Sbjct: 5 DFSTKRQIIDAINKVVYKGGRHANTRVGIEHLLRNHFVPEAGSRLDERVPQIAFVITGGK 64
Query: 952 SSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVN 1011
S + + L Q GV F +N D E+ +I + A S+ ++ +L ++
Sbjct: 65 SVEDAQDVSLALTQKGVKVFAVGVRNIDSEEVGKIASNSATAFRVGSVQELSELSETVLE 124
Query: 1012 LL 1013
L
Sbjct: 125 TL 126
Score = 48.4 bits (113), Expect = 0.001
Identities = 58/263 (22%), Positives = 105/263 (39%), Gaps = 38/263 (14%)
Query: 828 PLAQPESKRDILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVK----PEGTRIAVAQYSD 882
PL P ++ F D S + F +R+ L I+ +L + P G R+AV Y++
Sbjct: 703 PLECPVLPTELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNN 762
Query: 883 DVKVESRFDEHQSKPEILNLVKRMKIK-TGKALNLGYALDYAQRYIFVKSAGSRIEDGVL 941
+V E RF + K +L+ ++ +++ T K +L A+ + R F R+ G
Sbjct: 763 EVTTEIRFASSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTF-----KRVRSGFP 817
Query: 942 QFLVLLVAG----RSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE 997
V + R+S ++ L +G+ P +F D + + ++ + A
Sbjct: 818 MRKVAVFFSNKPTRASPQLREAVLKLSDAGITP-LFLTSQEDRQLINALQINNTAVGHAL 876
Query: 998 SLPKIGDLHPQIVNLL---------------------KSVHNGAPAPVSGEKDVVFLLDG 1036
LP DL + N+L S + A + D+ F+LD
Sbjct: 877 VLPARRDLTDFLKNVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDLAFILDS 936
Query: 1037 SEGVR-SGFPLLKEFVQRVVESL 1058
SE F +K+++ V+ L
Sbjct: 937 SEATTLFQFNEMKKYIGYVIRQL 959
Score = 46.9 bits (109), Expect = 0.004
Identities = 49/253 (19%), Positives = 108/253 (42%), Gaps = 24/253 (9%)
Query: 1233 DVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT----TRVAVIQFSDDPKAEFLLN 1287
++ F +D S+ + F +R ++ +V L + RVAV+ ++++ E
Sbjct: 712 ELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 771
Query: 1288 AHSSKDEVQNAVQRLRPK-GGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLI--- 1343
+ K + +++Q L+ +Q ++ A+ +V+RN FKR + G P V +
Sbjct: 772 SSKKKSALLDSIQNLQVALTSKQQSLETAMSFVARNTFKR-----VRSGFPMRKVAVFFS 826
Query: 1344 -SSGKSDDEVVVPAVELKQFGVAPFTIARNADQEELVKISLSPEYV---FSVSTFRELPS 1399
++ ++ ++L G+ P + D++ + + ++ V + R+L
Sbjct: 827 NKPTRASPQLREAVLKLSDAGITPLFLTSQEDRQLINALQINNTAVGHALVLPARRDLTD 886
Query: 1400 LEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAA------DIVFLIDSSEGVRPDGFA 1453
+ +LT L I + P + AA D+ F++DSSE F
Sbjct: 887 FLKNVLTCHVCLDICNIDPSCGFGSWRPSFRDRRAAGSDVDIDLAFILDSSEATTLFQFN 946
Query: 1454 HIRDFVSRIVRRL 1466
++ ++ ++R+L
Sbjct: 947 EMKKYIGYVIRQL 959
Score = 46.9 bits (109), Expect = 0.004
Identities = 22/44 (50%), Positives = 29/44 (65%), Gaps = 3/44 (6%)
Query: 2315 FPGYPGPKGNPGE---PGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
+ GYPG +G+PGE PG+NGT G +G G+RG G G G+K
Sbjct: 370 YRGYPGDEGDPGERGPPGVNGTQGFQGCPGQRGVKGSRGFPGEK 413
Score = 44.9 bits (104), Expect = 0.014
Identities = 30/96 (31%), Positives = 40/96 (41%), Gaps = 25/96 (26%)
Query: 2080 GTQGFQGCPGQRGVKGSRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRRGDK 2139
G G G PG+ G+ GS G PG+ SG +G G +G++
Sbjct: 484 GDIGPMGLPGRDGIPGSPGDPGKDG---------------------GSGRRGPAGAKGNR 522
Query: 2140 GPRGEKGERGDVGIRGDPGNPGQDSQERGPKGETGD 2175
G G+ G G+ G RG G PG GP G G+
Sbjct: 523 GGPGQPGFEGEQGTRGSQGPPG----PIGPPGLIGE 554
Score = 44.5 bits (103), Expect = 0.018
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G PG G+PG+ G +G GP G +G RG G PG G++
Sbjct: 496 GIPGSPGDPGKDGGSGRRGPAGAKGNRGGPGQPGFEGEQ 534
Score = 44.5 bits (103), Expect = 0.018
Identities = 17/39 (43%), Positives = 25/39 (63%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G G +G PG+PG G G +G +G G GPPG++G++
Sbjct: 517 GAKGNRGGPGQPGFEGEQGTRGSQGPPGPIGPPGLIGEQ 555
Score = 40.2 bits (92), Expect = 0.35
Identities = 18/39 (46%), Positives = 24/39 (61%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G G G G+ GL G++G KG GRRG+ GP G G++
Sbjct: 420 GLDGLDGEEGDKGLPGSSGEKGSPGRRGDKGPKGDKGER 458
Score = 39.9 bits (91), Expect = 0.46
Identities = 18/39 (46%), Positives = 25/39 (63%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G+PG KG GE GL+G G +G +G G+SG G G++
Sbjct: 408 GFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEKGSPGRR 446
Score = 39.5 bits (90), Expect = 0.60
Identities = 18/37 (48%), Positives = 20/37 (53%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVG 2353
G PG G G PG G GPKG +G RG+ G G G
Sbjct: 432 GLPGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPG 468
Score = 39.1 bits (89), Expect = 0.78
Identities = 44/187 (23%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGEND----FHFALVQFNGNPHTEFLLN 94
++ F +D+S + ++ F +RE L +V L + E++ A+V +N TE
Sbjct: 712 ELAFALDTSEGVTQDTFSRMREVLLGIVGDLTIAESNCPRGARVAVVTYNNEVTTEIRFA 771
Query: 95 TYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP--QVIVVLTDG 152
+ + K +L I N+ + Q + LE M S + + R G P +V V ++
Sbjct: 772 SSKKKSALLDSIQNLQVALTSKQ--QSLETAM-SFVARNTFKRVRSGFPMRKVAVFFSNK 828
Query: 153 HSKDGLALPSAELKSADVNV---FAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDI 209
++ L A LK +D + F ED +I + + H L L D
Sbjct: 829 PTRASPQLREAVLKLSDAGITPLFLTSQEDRQLINALQINNTAVG-HALVLPARRDLTDF 887
Query: 210 VGNLVSC 216
+ N+++C
Sbjct: 888 LKNVLTC 894
Score = 37.5 bits (85), Expect = 2.3
Identities = 17/39 (43%), Positives = 20/39 (50%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G G G G PG G TGP G +G G GP G +G +
Sbjct: 559 GPRGGGGTAGAPGERGRTGPLGRKGEPGEPGPKGSIGNR 597
Score = 37.5 bits (85), Expect = 2.3
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 6/74 (8%)
Query: 2080 GTQGFQGCPGQRGVKG---SRGFPGEKXXXXXXXXXXXXXXXXXXXXXXSSGEKGNPGRR 2136
G++G +G G+RG G +G PGE ++G+KG+PG
Sbjct: 612 GSEGRRGKKGERGFPGYPGPKGTPGEPGADGPPGPKGIRGRRGNSGPPGATGQKGDPGY- 670
Query: 2137 GDKGPRGEKGERGD 2150
GP G KG RGD
Sbjct: 671 --PGPSGHKGNRGD 682
Score = 37.5 bits (85), Expect = 2.3
Identities = 19/39 (48%), Positives = 21/39 (53%)
Query: 2316 PGYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQ 2354
PG G KG+PG G G G KG RG G G PG G+
Sbjct: 434 PGSSGEKGSPGRRGDKGPKGDKGERGDVGIRGDPGDSGR 472
Score = 36.0 bits (81), Expect = 6.8
Identities = 17/39 (43%), Positives = 21/39 (53%)
Query: 2317 GYPGPKGNPGEPGLNGTTGPKGIRGRRGNSGPPGIVGQK 2355
G G +G PGE G G G G+ G G+ G PG G+K
Sbjct: 402 GVKGSRGFPGEKGELGEIGLDGLDGEEGDKGLPGSSGEK 440
>pir||S28776 collagen alpha 3(VI) chain - human (fragment)
gb|AAB24261.1| (S49432) type VI collagen alpha 3 chain [human, Peptide Partial,
205 aa] [Homo sapiens]
Length = 205
Score = 406 bits (1032), Expect = e-111
Identities = 202/205 (98%), Positives = 202/205 (98%)
Query: 32 VKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEF 91
VKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEF
Sbjct: 1 VKNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEF 60
Query: 92 LLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTD 151
LLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIM HLTKAAGS AGDGVPQVIVVLTD
Sbjct: 61 LLNTYRTKQEVLSHISNMSYIGGTNQTGKGLEYIMAKHLTKAAGSLAGDGVPQVIVVLTD 120
Query: 152 GHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVG 211
GHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVG
Sbjct: 121 GHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVG 180
Query: 212 NLVSCVHSSVSPERAGDTETLKDIT 236
NLVSCVHSSVSPERAGDTETLKDIT
Sbjct: 181 NLVSCVHSSVSPERAGDTETLKDIT 205
Score = 110 bits (273), Expect = 2e-22
Identities = 60/179 (33%), Positives = 99/179 (54%), Gaps = 3/179 (1%)
Query: 240 SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTY 299
+ADIIFL+D S G +F ++ +FL ++++ L +G +VQF+ P T F L+TY
Sbjct: 6 AADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTY 65
Query: 300 STKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSS 359
TK +VL + + + GG G L++++ H T+A GS +GVPQV+V+++ G S
Sbjct: 66 RTKQEVLSHISNMSYIGG-TNQTGKGLEYIMAKHLTKAAGSLAGDGVPQVIVVLTDGHSK 124
Query: 360 DEIRYGVVALKQASVFSFGLGAQAASRAELQHIATD--DNLVFTVPEFRSFGDLQEKLL 416
D + LK A V F +G + A L+ IA++ + +F + F S D+ L+
Sbjct: 125 DGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLV 183
Score = 108 bits (268), Expect = 8e-22
Identities = 54/152 (35%), Positives = 93/152 (60%), Gaps = 1/152 (0%)
Query: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPT 504
DI+FLVD S +G +F +R+F+ V++ L +G++ A+ Q+ EF NT+ T
Sbjct: 8 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 67
Query: 505 KREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDE 564
K+EV++ + M + G+ TG L+++ T +AG A +G+P+++V++T G S D
Sbjct: 68 KQEVLSHISNMSYIGGTN-QTGKGLEYIMAKHLTKAAGSLAGDGVPQVIVVLTDGHSKDG 126
Query: 565 ISQPAQELKRSSIMAFAIGNKGADQAELEEIA 596
++ P+ ELK + + FAIG + AD+ L+EIA
Sbjct: 127 LALPSAELKSADVNVFAIGVEDADEGALKEIA 158
Score = 106 bits (262), Expect = 4e-21
Identities = 57/168 (33%), Positives = 94/168 (55%), Gaps = 3/168 (1%)
Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698
DIIFL+D S +G+ +F VR+F+ ++V SL +G ++ LVQF+ P TEF LNTY+T
Sbjct: 8 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 67
Query: 699 KSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDS 758
K ++ L Y+ A H T+A GS + VPQ++++LT G S+D
Sbjct: 68 KQEV-LSHISNMSYIGGTNQTGKGLEYIMAKHLTKAAGSLAGDGVPQVIVVLTDGHSKDG 126
Query: 759 YLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYL--MDDFSS 804
+ L A + F +G A++ L++IA P +++ +++F+S
Sbjct: 127 LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTS 174
Score = 101 bits (248), Expect = 2e-19
Identities = 60/168 (35%), Positives = 96/168 (56%), Gaps = 8/168 (4%)
Query: 1016 VHNGAPAPVSGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSD 1074
V NGA A D++FL+D S + F L++EF+ VV+SL VG++ A+VQ++
Sbjct: 1 VKNGAAA------DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNG 54
Query: 1075 RTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQ 1134
EF LN+Y KQ+V++ + ++ +GG T TG LE+++ L +AGS +GVPQ
Sbjct: 55 NPHTEFLLNTYRTKQEVLSHISNMSYIGG-TNQTGKGLEYIMAKHLTKAAGSLAGDGVPQ 113
Query: 1135 LLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIP 1182
+++VLT S D + PS +K IG+ +AD ++ I+ P
Sbjct: 114 VIVVLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEP 161
Score = 98.3 bits (241), Expect = 1e-18
Identities = 57/174 (32%), Positives = 97/174 (54%), Gaps = 3/174 (1%)
Query: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTY 1493
AADI+FL+DSS + + F +R+F+ +V+ L +G + +VQF+ + EF L TY
Sbjct: 6 AADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTY 65
Query: 1494 RSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQ 1553
R++ VL I + GG+ TGK LE++ K+AGS DGVPQ +V++ G S+
Sbjct: 66 RTKQEVLSHISNMSYIGGTN-QTGKGLEYIMAKHLTKAAGSLAGDGVPQVIVVLTDGHSK 124
Query: 1554 DDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP--RLVFTVREFRELPNI 1605
D ++ + ++S+ + +G + D L+ I ++P +F + F L +I
Sbjct: 125 DGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDI 178
Score = 97.9 bits (240), Expect = 2e-18
Identities = 61/191 (31%), Positives = 101/191 (51%), Gaps = 5/191 (2%)
Query: 1229 GGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLN 1287
G D++FL+D S + G E FQ VR + +V L VG + A++QF+ +P EFLLN
Sbjct: 4 GAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLN 63
Query: 1288 AHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGK 1347
+ +K EV + + + GG G LEY+ + GS +GVPQ +V+++ G
Sbjct: 64 TYRTKQEVLSHISNMSYIGGTN-QTGKGLEYIMAKHLTKAAGSLAGDGVPQVIVVLTDGH 122
Query: 1348 SDDEVVVPAVELKQFGVAPFTI-ARNADQEELVKISLSP--EYVFSVSTFRELPSLEQKL 1404
S D + +P+ ELK V F I +AD+ L +I+ P ++F++ F L + L
Sbjct: 123 SKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNL 182
Query: 1405 LTPITTLTSEQ 1415
++ + + S +
Sbjct: 183 VSCVHSSVSPE 193
Score = 93.6 bits (229), Expect = 3e-17
Identities = 53/154 (34%), Positives = 81/154 (52%), Gaps = 1/154 (0%)
Query: 1638 ADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDFS 1697
ADI+FL+D S + FQ V F+ ++V ++ + LVQ+N +P EF L +
Sbjct: 7 ADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYR 66
Query: 1698 TKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSVE 1757
TK++++ I+ + Y GG + K GLE++ H AGS VPQ+ V+T G S +
Sbjct: 67 TKQEVLSHISNMSYIGGTNQTGK-GLEYIMAKHLTKAAGSLAGDGVPQVIVVLTDGHSKD 125
Query: 1758 DAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIAS 1791
S L V VFA+GV + D + +IAS
Sbjct: 126 GLALPSAELKSADVNVFAIGVEDADEGALKEIAS 159
Score = 83.1 bits (202), Expect = 4e-14
Identities = 56/196 (28%), Positives = 95/196 (47%), Gaps = 3/196 (1%)
Query: 837 DILFLFDGSANLVGQ-FPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQS 895
DI+FL D S + + F +VR+FLY ++ L V A+ Q++ + E + +++
Sbjct: 8 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 67
Query: 896 KPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRSSDR 955
K E+L+ + M G G L+Y K+AGS DGV Q +V+L G S D
Sbjct: 68 KQEVLSHISNMSY-IGGTNQTGKGLEYIMAKHLTKAAGSLAGDGVPQVIVVLTDGHSKDG 126
Query: 956 VDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNLLKS 1015
+ P++ LK + V F ++AD L++I P + +L LH + NL+
Sbjct: 127 LALPSAELKSADVNVFAIGVEDADEGALKEIASEP-LNMHMFNLENFTSLHDIVGNLVSC 185
Query: 1016 VHNGAPAPVSGEKDVV 1031
VH+ +G+ + +
Sbjct: 186 VHSSVSPERAGDTETL 201
>gb|AAG28506.1|AF197573_1 (AF197573) type VI collagen alpha 3 chain [Canis familiaris]
Length = 246
Score = 397 bits (1009), Expect = e-108
Identities = 199/246 (80%), Positives = 213/246 (85%)
Query: 1749 VITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNXXXXXXX 1808
VITGGKSVEDAQ+ SLALTQ+GVKVFAVGV+NIDSEEVGKIASNSATAFRVGN
Sbjct: 1 VITGGKSVEDAQEASLALTQKGVKVFAVGVKNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 1809 XXXXXXXXHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNR 1868
HDAMHETLCPGVTD +K CNLDVILGFDGSRDQNVFV QKG ESK+DAILNR
Sbjct: 61 SEQVLETLHDAMHETLCPGVTDISKVCNLDVILGFDGSRDQNVFVTQKGLESKMDAILNR 120
Query: 1869 ISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTED 1928
ISQM R+SCSG + PTVRVSVVANTPSGPVEAFDF EYQPE+ EKFRNMR+QHPYVLT D
Sbjct: 121 ISQMQRISCSGSQMPTVRVSVVANTPSGPVEAFDFAEYQPELFEKFRNMRNQHPYVLTAD 180
Query: 1929 TLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988
TLKVY NKFRQSS D+VKVVIHFTDG DG+LADL +ASE LRQEGV+ALILVGLERV NL
Sbjct: 181 TLKVYQNKFRQSSADNVKVVIHFTDGVDGNLADLQKASEELRQEGVQALILVGLERVANL 240
Query: 1989 ERLMHL 1994
E+LM L
Sbjct: 241 EQLMQL 246
Score = 39.9 bits (91), Expect = 0.46
Identities = 18/67 (26%), Positives = 34/67 (49%)
Query: 1546 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNI 1605
++ GGKS +D + + G+ VG +NID E+ I ++ F V +EL +
Sbjct: 1 VITGGKSVEDAQEASLALTQKGVKVFAVGVKNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 1606 EERIMNS 1612
E+++ +
Sbjct: 61 SEQVLET 67
Score = 38.3 bits (87), Expect = 1.3
Identities = 17/49 (34%), Positives = 30/49 (60%)
Query: 555 LITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF 603
+ITGGKS+++ + + L + + FA+G K D E+ +IA +S+ F
Sbjct: 1 VITGGKSVEDAQEASLALTQKGVKVFAVGVKNIDSEEVGKIASNSATAF 49
Score = 36.4 bits (82), Expect = 5.2
Identities = 21/65 (32%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Query: 1342 LISSGKSDDEVVVPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSL 1400
+I+ GKS ++ ++ L Q GV F + +N D EE+ KI+ + F V +EL L
Sbjct: 1 VITGGKSVEDAQEASLALTQKGVKVFAVGVKNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 1401 EQKLL 1405
+++L
Sbjct: 61 SEQVL 65
Score = 35.6 bits (80), Expect = 8.9
Identities = 28/107 (26%), Positives = 50/107 (46%), Gaps = 9/107 (8%)
Query: 148 VLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLN-MHMFNLENFTSL 206
V+T G S + S L V VFA+GV++ D + +IAS + N++ + L
Sbjct: 1 VITGGKSVEDAQEASLALTQKGVKVFAVGVKNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 207 HD-IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNN 252
+ ++ L +H ++ P + DI+ + D+I DGS +
Sbjct: 61 SEQVLETLHDAMHETLCP-------GVTDISKVCNLDVILGFDGSRD 100
>gb|AAF79924.1|AF129288_1 (AF129288) type VI collagen alpha 3 chain [Ovis aries]
Length = 246
Score = 387 bits (984), Expect = e-106
Identities = 194/246 (78%), Positives = 212/246 (85%)
Query: 1749 VITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNXXXXXXX 1808
VITGGKSVEDAQ+ S+ALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGN
Sbjct: 1 VITGGKSVEDAQEASMALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 1809 XXXXXXXXHDAMHETLCPGVTDAAKACNLDVILGFDGSRDQNVFVAQKGFESKVDAILNR 1868
HDAMHETLCPG+TD +KACNLDVILGFDGSRDQNVFVAQKG ESK+DAIL R
Sbjct: 61 SEQVLETLHDAMHETLCPGMTDVSKACNLDVILGFDGSRDQNVFVAQKGLESKMDAILRR 120
Query: 1869 ISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEYQPEMLEKFRNMRSQHPYVLTED 1928
ISQM ++SCSG + PTVRVSVVA TPSGPVEAFDF EYQ E+ EKF+NMR+QHPYVLT D
Sbjct: 121 ISQMQKISCSGSQLPTVRVSVVALTPSGPVEAFDFAEYQSELFEKFQNMRAQHPYVLTAD 180
Query: 1929 TLKVYLNKFRQSSPDSVKVVIHFTDGADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988
TLK+Y NKF+Q+S D+VKVVIHFTDG DGDLAD+ RASE LRQ+GVRALILVGLERV NL
Sbjct: 181 TLKLYQNKFQQASSDNVKVVIHFTDGVDGDLADVQRASEELRQDGVRALILVGLERVANL 240
Query: 1989 ERLMHL 1994
E+LM L
Sbjct: 241 EQLMQL 246
Score = 41.4 bits (95), Expect = 0.16
Identities = 19/67 (28%), Positives = 34/67 (50%)
Query: 1546 LVLGGKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNI 1605
++ GGKS +D + + G+ VG RNID E+ I ++ F V +EL +
Sbjct: 1 VITGGKSVEDAQEASMALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 1606 EERIMNS 1612
E+++ +
Sbjct: 61 SEQVLET 67
Score = 37.5 bits (85), Expect = 2.3
Identities = 22/65 (33%), Positives = 36/65 (54%), Gaps = 1/65 (1%)
Query: 1342 LISSGKSDDEVVVPAVELKQFGVAPFTIA-RNADQEELVKISLSPEYVFSVSTFRELPSL 1400
+I+ GKS ++ ++ L Q GV F + RN D EE+ KI+ + F V +EL L
Sbjct: 1 VITGGKSVEDAQEASMALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 1401 EQKLL 1405
+++L
Sbjct: 61 SEQVL 65
Score = 37.5 bits (85), Expect = 2.3
Identities = 16/49 (32%), Positives = 30/49 (60%)
Query: 555 LITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVF 603
+ITGGKS+++ + + L + + FA+G + D E+ +IA +S+ F
Sbjct: 1 VITGGKSVEDAQEASMALTQRGVKVFAVGVRNIDSEEVGKIASNSATAF 49
Score = 35.6 bits (80), Expect = 8.9
Identities = 27/107 (25%), Positives = 49/107 (45%), Gaps = 9/107 (8%)
Query: 148 VLTDGHSKDGLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLN-MHMFNLENFTSL 206
V+T G S + S L V VFA+GV + D + +IAS + N++ + L
Sbjct: 1 VITGGKSVEDAQEASMALTQRGVKVFAVGVRNIDSEEVGKIASNSATAFRVGNVQELSEL 60
Query: 207 HD-IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNN 252
+ ++ L +H ++ P + D++ + D+I DGS +
Sbjct: 61 SEQVLETLHDAMHETLCP-------GMTDVSKACNLDVILGFDGSRD 100
>gb|AAC23668.1| (AF064750) type VI collagen alpha 3 subunit N7 domain [Mus
musculus]
Length = 200
Score = 274 bits (693), Expect = 1e-71
Identities = 138/200 (69%), Positives = 156/200 (78%)
Query: 633 VHSNKRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFS 692
VH NKRDIIFLLDGS NVGK NFPYVRDFV NLVNSLD+G+DNIRVGLVQFSDTPVTEFS
Sbjct: 1 VHVNKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFS 60
Query: 693 LNTYQTKSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTA 752
L+TYQTKS++ SALSY++ANHFTEAGGSR R HVPQLLLLL A
Sbjct: 61 LDTYQTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMA 120
Query: 753 GQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAFNPSLVYLMDDFSSXXXXXXXX 812
G SED+YLQAA+A+ R+G+LT CVG ++A+KAE E IAFNPSLVY+MDDF S
Sbjct: 121 GPSEDAYLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYVMDDFRSLPYLPQQP 180
Query: 813 XXXXTTYVSGGVEEVPLAQP 832
TTYVSGGV+EVPL+QP
Sbjct: 181 IQPLTTYVSGGVQEVPLSQP 200
Score = 159 bits (397), Expect = 6e-37
Identities = 84/194 (43%), Positives = 119/194 (61%), Gaps = 4/194 (2%)
Query: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYST 301
DIIFL+DGS+N G NF + DF+ NL+ L +G+ IRVG+VQFSD P T FSLDTY T
Sbjct: 7 DIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTYQT 66
Query: 302 KAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDE 361
K+++L ++ L GG N G AL ++ NHFT AGGSR VPQ+L+L+ AGPS D
Sbjct: 67 KSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMAGPSEDA 126
Query: 362 IRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEK----LLP 417
A+ ++ V + +G A +AE +HIA + +LV+ + +FRS L ++ L
Sbjct: 127 YLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYVMDDFRSLPYLPQQPIQPLTT 186
Query: 418 YIVGVAQRHIVLKP 431
Y+ G Q + +P
Sbjct: 187 YVSGGVQEVPLSQP 200
Score = 146 bits (364), Expect = 4e-33
Identities = 74/188 (39%), Positives = 114/188 (60%), Gaps = 2/188 (1%)
Query: 439 IEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFY 498
+ VNKRDI+FL+DGS +G NF +RDF+ ++ L++G D I+V + Q++DT EF
Sbjct: 1 VHVNKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFS 60
Query: 499 FNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITG 558
+T+ TK E++ +R+++ GS L GSAL ++ N FT + G R +P+LL+L+
Sbjct: 61 LDTYQTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMA 120
Query: 559 GKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFIPAEFRAAPLQGMLP 618
G S D Q A + RS ++ +G AD+AE E IAF+ SLV++ +FR+ P P
Sbjct: 121 GPSEDAYLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYVMDDFRSLPYLPQQP 180
Query: 619 GLLAPLRT 626
+ PL T
Sbjct: 181 --IQPLTT 186
Score = 141 bits (352), Expect = 1e-31
Identities = 70/179 (39%), Positives = 114/179 (63%)
Query: 1430 VESDAADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFY 1489
V + DI+FL+D S+ V + F ++RDFV+ +V L++G +RVG+VQFS+ EF
Sbjct: 1 VHVNKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFS 60
Query: 1490 LKTYRSQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLG 1549
L TY++++ +L +RRL+L+GGS LN G AL ++ N F ++ GSR VPQ L+L++
Sbjct: 61 LDTYQTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMA 120
Query: 1550 GKSQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDPRLVFTVREFRELPNIEER 1608
G S+D + A + SG+++L VG D+ E + I +P LV+ + +FR LP + ++
Sbjct: 121 GPSEDAYLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYVMDDFRSLPYLPQQ 179
Score = 137 bits (342), Expect = 2e-30
Identities = 75/191 (39%), Positives = 112/191 (58%), Gaps = 2/191 (1%)
Query: 1231 KRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAH 1289
KRD++FL+DGS + G F YVR + LV+ LDVG D RV ++QFSD P EF L+ +
Sbjct: 5 KRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTY 64
Query: 1290 SSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSD 1349
+K E+ ++RL+ KGG +N G+AL Y+ N F GSR VPQ L+L+ +G S+
Sbjct: 65 QTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMAGPSE 124
Query: 1350 DEVVVPAVELKQFGVAPFTI-ARNADQEELVKISLSPEYVFSVSTFRELPSLEQKLLTPI 1408
D + A + + GV + AD+ E I+ +P V+ + FR LP L Q+ + P+
Sbjct: 125 DAYLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYVMDDFRSLPYLPQQPIQPL 184
Query: 1409 TTLTSEQIQKL 1419
TT S +Q++
Sbjct: 185 TTYVSGGVQEV 195
Score = 121 bits (300), Expect = 1e-25
Identities = 65/174 (37%), Positives = 101/174 (57%), Gaps = 1/174 (0%)
Query: 1027 EKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSY 1085
++D++FLLDGS+ V ++ FP +++FV +V SLDVG D +RV +VQ+SD EF L++Y
Sbjct: 5 KRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTY 64
Query: 1086 MNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSG 1145
K +++ +R+L L GG N G+AL ++ N + GSR VPQLL++L A S
Sbjct: 65 QTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMAGPSE 124
Query: 1146 DDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQLGTVQQ 1199
D + + R G + + +G AD E + I+F P + FR L + Q
Sbjct: 125 DAYLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYVMDDFRSLPYLPQ 178
Score = 112 bits (277), Expect = 7e-23
Identities = 62/169 (36%), Positives = 99/169 (57%), Gaps = 3/169 (1%)
Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
DIIFL+D S +G+ +F VR+F+ ++V SL VG ++ LVQF+ P TEF L+TY+T
Sbjct: 7 DIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTYQT 66
Query: 99 KQEVLSHISNMSYIGGTN-QTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDG 157
K E+L+H+ + GG+ G L YI +H T+A GSR VPQ++++L G S+D
Sbjct: 67 KSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMAGPSEDA 126
Query: 158 LALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSL 206
+ + + V +G AD+ + IA P +++ +++F SL
Sbjct: 127 YLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYV--MDDFRSL 173
Score = 111 bits (276), Expect = 9e-23
Identities = 65/187 (34%), Positives = 100/187 (52%), Gaps = 1/187 (0%)
Query: 834 SKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDE 892
+KRDI+FL DGS N+ FP VRDF+ +++ L+V + R+ + Q+SD E D
Sbjct: 4 NKRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDT 63
Query: 893 HQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGRS 952
+Q+K E+L ++R+++K G LN G AL Y F ++ GSR V Q L+LL+AG S
Sbjct: 64 YQTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMAGPS 123
Query: 953 SDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAESLPKIGDLHPQIVNL 1012
D A + +SGV+ AD AE E I +P+ + + + L Q +
Sbjct: 124 EDAYLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVYVMDDFRSLPYLPQQPIQP 183
Query: 1013 LKSVHNG 1019
L + +G
Sbjct: 184 LTTYVSG 190
Score = 102 bits (251), Expect = 8e-20
Identities = 54/161 (33%), Positives = 85/161 (52%)
Query: 1637 KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDF 1696
K DI+FLLDGS N +++F V FV+ +V+++ D+I+VGLVQ++ P EF L +
Sbjct: 5 KRDIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDNIRVGLVQFSDTPVTEFSLDTY 64
Query: 1697 STKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSV 1756
TK +++ + ++ KGG N L ++ NHF GSR VPQ+ ++ G S
Sbjct: 65 QTKSELLAHLRRLQLKGGSGLNAGSALSYIHANHFTEAGGSRTRAHVPQLLLLLMAGPSE 124
Query: 1757 EDAQDVSLALTQRGVKVFAVGVRNIDSEEVGKIASNSATAF 1797
+ + A+ + GV VG D E IA N + +
Sbjct: 125 DAYLQAADAMVRSGVLTLCVGTTRADKAESEHIAFNPSLVY 165
Score = 43.4 bits (100), Expect = 0.040
Identities = 41/147 (27%), Positives = 68/147 (45%), Gaps = 24/147 (16%)
Query: 2619 DMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDNA 2678
D+ F+LD ++ F ++ ++ LV LD+ D RV +VQ + +
Sbjct: 7 DIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDN------IRVGLVQFSDT------ 54
Query: 2679 SMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRAL--GSAIEYTIENVFESAPNPRDL 2736
PV EFSL Y +K +L+ L R QL+G L GSA+ Y N F A R
Sbjct: 55 ---PV-TEFSLDTYQTKSELLAHLRR--LQLKGGSGLNAGSALSYIHANHFTEAGGSRTR 108
Query: 2737 ----KIVVLMLTGEVPEQQLEEAQRVI 2759
++++L++ G + L+ A ++
Sbjct: 109 AHVPQLLLLLMAGPSEDAYLQAADAMV 135
Score = 43.4 bits (100), Expect = 0.040
Identities = 29/98 (29%), Positives = 51/98 (51%), Gaps = 5/98 (5%)
Query: 2402 ELAFALDTSEGVNQDTFGRMRDVVLSIVNVLTIAESNCPTGARVAVVTYNNEVTTEIRFA 2461
++ F LD S+ V ++ F +RD V ++VN L + N RV +V +++ TE
Sbjct: 7 DIIFLLDGSDNVGKNNFPYVRDFVTNLVNSLDVGSDN----IRVGLVQFSDTPVTEFSLD 62
Query: 2462 DSKRKSVLLDKIKNLQVALTSKQQSLETAMSFVARNTF 2499
+ KS LL ++ LQ+ S + +A+S++ N F
Sbjct: 63 TYQTKSELLAHLRRLQLKGGSGLNA-GSALSYIHANHF 99
>gb|AAF19243.1|AC007363_1 (AC007363) similar to Coch-5B2 [Homo sapiens]
Length = 678
Score = 179 bits (450), Expect = 4e-43
Identities = 113/361 (31%), Positives = 198/361 (54%), Gaps = 17/361 (4%)
Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
D+ FL+D S +IG+ F++ ++ L DV ++L +G +VQ+ NP T F L T+
Sbjct: 293 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 352
Query: 99 KQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDGL 158
+++ + I ++ GG + G+ + ++ ++ +KA G+R+G P V+VV+ DG D +
Sbjct: 353 SRDLKTAIEKITQRGGLSNVGRAISFVTKNFFSKANGNRSG--APNVVVVMVDGWPTDKV 410
Query: 159 ALPSAELKSADVNVFAIGVEDADEGALKEIASEP--LNMHMFNLENFTSLHDIVGNLVSC 216
S + + +N+F I +E A E K+ EP N + F SLH V +
Sbjct: 411 EEASRLARESGINIFFITIEGAAENE-KQYVVEPNFANKAVCRTNGFYSLH--VQSWFG- 466
Query: 217 VHSSVSP--ERAGDTETLK-DITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLP 273
+H ++ P +R DT+ L T +SADI F+IDGS++ G+ NF +L F+ NL ++
Sbjct: 467 LHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFE 526
Query: 274 IGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENH 333
I R+G VQ++ E R F D YS+K +L A+K +G+ G + G A++F +E
Sbjct: 527 ISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGG-TSTGAAINFALEQL 585
Query: 334 FTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIA 393
F ++ ++ ++++LI+ G S D++R +A V ++ +G A++ EL+ IA
Sbjct: 586 FKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIA 640
Query: 394 T 394
T
Sbjct: 641 T 641
Score = 159 bits (397), Expect = 6e-37
Identities = 109/386 (28%), Positives = 191/386 (49%), Gaps = 28/386 (7%)
Query: 223 PERAGDTETLKDITAQD---SADIIFLIDGSNNTGSVNFAVILDFLVNLLEKLPIGTQQI 279
P+ T++L+ ++ D D+ FLIDGS + G F + L ++ + L IG
Sbjct: 271 PKEELSTQSLEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGP 330
Query: 280 RVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFVVENHFTRAGG 339
+GVVQ+ D P T F+L T++ + A++ + GG L+N+G A+ FV +N F++A G
Sbjct: 331 LMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGG-LSNVGRAISFVTKNFFSKANG 389
Query: 340 SRVEEGVPQVLVLISAGPSSDEIRYGVVALKQASVFSFGLGAQAASRAELQHIATDDNLV 399
+R G P V+V++ G +D++ +++ + F + + A+ E Q++ + N
Sbjct: 390 NR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVV-EPNFA 446
Query: 400 ---------FTVPEFRSFGDLQEKLLPYIVGVAQRHIVLKPPTIVTQVIEVNKRDIVFLV 450
F +S+ L + L P + V + T + N DI F++
Sbjct: 447 NKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCL------NSADIGFVI 500
Query: 451 DGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTHPTKREVIT 510
DGSS++G NF + F+ + + EI ++ QY R EF F+ + +K +++
Sbjct: 501 DGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILN 560
Query: 511 AVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSLDEISQPAQ 570
A++++ G TG+A++F LF S + KL++LIT G+S D++ PA
Sbjct: 561 AIKRVGYWSGGT-STGAAINFALEQLFKKSKPNKR-----KLMILITDGRSYDDVRIPAM 614
Query: 571 ELKRSSIMAFAIGNKGADQAELEEIA 596
++ +AIG A Q ELE IA
Sbjct: 615 AAHLKGVITYAIGVAWAAQEELEVIA 640
Score = 139 bits (346), Expect = 6e-31
Identities = 108/407 (26%), Positives = 190/407 (46%), Gaps = 15/407 (3%)
Query: 1210 REELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGPE-FQYVRTLIERLVDYLDVGFDT 1268
+EELS L+P+ K D+ FLIDGS S G F+ + L+ + LD+G
Sbjct: 272 KEELSTQS--LEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAG 329
Query: 1269 TRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPL 1328
+ V+Q+ D+P F L H++ +++ A++++ +GG NVG A+ +V++N F +
Sbjct: 330 PLMGVVQYGDNPATHFNLKTHTNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKAN 388
Query: 1329 GSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTIARNADQEELVKISLSPEYV 1388
G+R G P +V++ G D+V + ++ G+ F I E + + P +
Sbjct: 389 GNR--SGAPNVVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFA 446
Query: 1389 F-SVSTFRELPSLEQKLLTPITTLTSEQIQKLLASTRYPPPAVESDAADIVFLIDSSEGV 1447
+V SL + + ++++ + R ++ADI F+ID S V
Sbjct: 447 NKAVCRTNGFYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSV 506
Query: 1448 RPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIRRLR 1507
F + FV+ + + I + R+G VQ++ + EF Y S+ +L+AI+R+
Sbjct: 507 GTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVG 566
Query: 1508 LRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIRSSG 1567
G +TG A+ F LF KS ++ + ++L+ G+S DDV A G
Sbjct: 567 YWSGG-TSTGAAINFALEQLFKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKG 620
Query: 1568 IVSLGVGDRNIDRTELQTITNDPRL--VFTVREFRELPNIEERIMNS 1612
+++ +G + EL+ I P F V EF L RI+ +
Sbjct: 621 VITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQN 667
Score = 136 bits (340), Expect = 3e-30
Identities = 105/375 (28%), Positives = 181/375 (48%), Gaps = 22/375 (5%)
Query: 443 KRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYADTVRPEFYFNTH 502
K D+ FL+DGS+++G F + +A V Q L+IG + V QY D F TH
Sbjct: 291 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 350
Query: 503 PTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPKLLVLITGGKSL 562
R++ TA+ K+ G + G A+ FV N F+ + G R+ G P ++V++ G
Sbjct: 351 TNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNRS--GAPNVVVVMVDGWPT 407
Query: 563 DEISQPAQELKRSSIMAFAIGNKGADQAELEEIA---FDSSLVFIPAEFRAAPLQGM--L 617
D++ + ++ + S I F I +GA + E + + F + V F + +Q L
Sbjct: 408 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 467
Query: 618 PGLLAPL-RTLSGTPEVHSNKR-----DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDI 671
L PL + + T + +K DI F++DGS++VG NF V FV NL +I
Sbjct: 468 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 527
Query: 672 GNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXXXXXXXXSALSYVYANHF 731
+ + R+G VQ++ EF + Y +K DI +A+++ F
Sbjct: 528 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDI-LNAIKRVGYWSGGTSTGAAINFALEQLF 586
Query: 732 TEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVGASQANKAELEQIAF 791
++ + + +L++L+T G+S D A A G++T+ +G + A + ELE IA
Sbjct: 587 KKS-----KPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 641
Query: 792 NPSL--VYLMDDFSS 804
+P+ + +D+F +
Sbjct: 642 HPARDHSFFVDEFDN 656
Score = 131 bits (327), Expect = 1e-28
Identities = 99/374 (26%), Positives = 179/374 (47%), Gaps = 25/374 (6%)
Query: 824 VEEVPLAQPESKRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSD 882
+E V L P K D+ FL DGS ++ +F + + L + L++ P G + V QY D
Sbjct: 280 LEPVSLGDPNCKIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGD 339
Query: 883 DVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQ 942
+ H + ++ ++++ + G + N+G A+ + + F K+ G+R G
Sbjct: 340 NPATHFNLKTHTNSRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPN 396
Query: 943 FLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVLSPAFILAAE----- 997
+V++V G +D+V+ + ++SG+ F + A E +Q V+ P F A
Sbjct: 397 VVVVMVDGWPTDKVEEASRLARESGINIFFITIEGAAENE-KQYVVEPNFANKAVCRTNG 455
Query: 998 ----SLPKIGDLHPQIVNLLKSVHNGAPAPVS----GEKDVVFLLDGSEGVRSG-FPLLK 1048
+ LH + L+K V + S D+ F++DGS V +G F +
Sbjct: 456 FYSLHVQSWFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVL 515
Query: 1049 EFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMNKQDVVNAVRQLTLLGGPTPNT 1108
+FV + + ++ R+ VQY+ R EF + Y +K D++NA++++ G T +T
Sbjct: 516 QFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSGGT-ST 574
Query: 1109 GAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDDVRNPSVVVKRGGAVPIGIGIG 1168
GAA+ F L + S ++ +L+I++T RS DDVR P++ G + IG+
Sbjct: 575 GAAINFALEQLFKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVA 629
Query: 1169 NADITEMQTISFIP 1182
A E++ I+ P
Sbjct: 630 WAAQEELEVIATHP 643
Score = 128 bits (318), Expect = 1e-27
Identities = 100/363 (27%), Positives = 167/363 (45%), Gaps = 17/363 (4%)
Query: 637 KRDIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTY 696
K D+ FL+DGS ++GK F + + ++ +LDIG +G+VQ+ D P T F+L T+
Sbjct: 291 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 350
Query: 697 QTKSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSE 756
D+ A+S+V N F++A G+R P +++++ G
Sbjct: 351 TNSRDLKTAIEKITQRGGLSNVGR-AISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 407
Query: 757 DSYLQAANALTRAGILTFCV---GASQANKAELEQIAFNPSLVYLMDDFSSXXXXX-XXX 812
D +A+ +GI F + GA++ K + + F V + F S
Sbjct: 408 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSLHVQSWFGL 467
Query: 813 XXXXTTYVSGGVEEVPLAQPES---KRDILFLFDGSANL-VGQFPVVRDFLYKIIDELNV 868
V + LA ++ DI F+ DGS+++ G F V F+ + E +
Sbjct: 468 HKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEI 527
Query: 869 KPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIF 928
TRI QY+ + ++E FD++ SKP+ILN +KR+ +G + G A+++A +F
Sbjct: 528 SDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGAAINFALEQLF 586
Query: 929 VKSAGSRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL 988
KS ++ + ++L+ GRS D V PA GV+ + A ELE I
Sbjct: 587 KKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEVIAT 641
Query: 989 SPA 991
PA
Sbjct: 642 HPA 644
Score = 122 bits (304), Expect = 5e-26
Identities = 106/404 (26%), Positives = 185/404 (45%), Gaps = 38/404 (9%)
Query: 1029 DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEFYLNSYMN 1087
D+ FL+DGS + + F + K+ + V ++LD+G + VVQY D F L ++ N
Sbjct: 293 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 352
Query: 1088 KQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLTADRSGDD 1147
+D+ A+ ++T GG N G A+ FV +N + G+R G P +++V+ D
Sbjct: 353 SRDLKTAIEKITQRGG-LSNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDK 409
Query: 1148 VRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFA------------VAIPTFRQLG 1195
V S + + G I I A E Q + P+FA + + ++ L
Sbjct: 410 VEEASRLARESGINIFFITIEGAAENEKQYV-VEPNFANKAVCRTNGFYSLHVQSWFGLH 468
Query: 1196 TVQQVISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQSAGP-EFQYVRTL 1254
Q + +RV R S+ D+ F+IDGS S G F+ V
Sbjct: 469 KTLQPLVKRVCDTDRLACSKT-----------CLNSADIGFVIDGSSSVGTGNFRTVLQF 517
Query: 1255 IERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGN 1314
+ L ++ TR+ +Q++ + + EF + +SSK ++ NA++R+ G + G
Sbjct: 518 VTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG-GTSTGA 576
Query: 1315 ALEYVSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTI-ARNA 1373
A+ + +FK+ ++ + ++LI+ G+S D+V +PA+ GV + I A
Sbjct: 577 AINFALEQLFKKSKPNK-----RKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWA 631
Query: 1374 DQEELVKISLSP--EYVFSVSTFRELPSLEQKLLTPITTLTSEQ 1415
QEEL I+ P ++ F V F L +++ I T + Q
Sbjct: 632 AQEELEVIATHPARDHSFFVDEFDNLHQYVPRIIQNICTEFNSQ 675
Score = 119 bits (295), Expect = 5e-25
Identities = 97/366 (26%), Positives = 167/366 (45%), Gaps = 21/366 (5%)
Query: 1436 DIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRS 1495
D+ FLID S + F + ++ + + L+IGP+ +GVVQ+ ++ F LKT+ +
Sbjct: 293 DLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTHTN 352
Query: 1496 QAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDD 1555
+ AI ++ RGG N G+A+ FV +N F K+ G+R G P +V+++ G D
Sbjct: 353 SRDLKTAIEKITQRGGLS-NVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPTDK 409
Query: 1556 VSRFAQVIRSSGIVSLGVGDRNIDRTELQTITNDP---RLVFTVREFRELPNIEERIMNS 1612
V +++ R SGI + E Q + + V F L + +
Sbjct: 410 VEEASRLARESGINIFFITIEGAAENEKQYVVEPNFANKAVCRTNGFYSL-----HVQSW 464
Query: 1613 FGPSXXXXXXXX----XXXXXXSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDT 1668
FG S+ ADI F++DGS + +F+ VL+FV+ +
Sbjct: 465 FGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSSVGTGNFRTVLQFVTNLTKE 524
Query: 1669 VYEDGDSIQVGLVQYNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRV 1728
++G VQY + EF +S+K I++AI +V Y G T G +
Sbjct: 525 FEISDTDTRIGAVQYTYEQRLEFGFDKYSSKPDILNAIKRVGYWSG---GTSTG---AAI 578
Query: 1729 NHFVPEAGSRLDQRVPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSEEVGK 1788
N + + + ++ +IT G+S +D + ++A +GV +A+GV EE+
Sbjct: 579 NFALEQLFKKSKPNKRKLMILITDGRSYDDVRIPAMAAHLKGVITYAIGVAWAAQEELEV 638
Query: 1789 IASNSA 1794
IA++ A
Sbjct: 639 IATHPA 644
Score = 89.7 bits (219), Expect = 4e-16
Identities = 47/178 (26%), Positives = 92/178 (51%), Gaps = 5/178 (2%)
Query: 37 AADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTY 96
+ADI F++D S ++G +F+ V +F+ ++ K + + D VQ+ EF + Y
Sbjct: 493 SADIGFVIDGSSSVGTGNFRTVLQFVTNLTKEFEISDTDTRIGAVQYTYEQRLEFGFDKY 552
Query: 97 RTKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKD 156
+K ++L+ I + Y G TG + + ++ K+ ++ ++++++TDG S D
Sbjct: 553 SSKPDILNAIKRVGYWSGGTSTGAAINFALEQLFKKSKPNKR-----KLMILITDGRSYD 607
Query: 157 GLALPSAELKSADVNVFAIGVEDADEGALKEIASEPLNMHMFNLENFTSLHDIVGNLV 214
+ +P+ V +AIGV A + L+ IA+ P H F ++ F +LH V ++
Sbjct: 608 DVRIPAMAAHLKGVITYAIGVAWAAQEELEVIATHPARDHSFFVDEFDNLHQYVPRII 665
Score = 64.0 bits (153), Expect = 2e-08
Identities = 75/336 (22%), Positives = 137/336 (40%), Gaps = 33/336 (9%)
Query: 1637 KADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQYNSDPTDEFFLKDF 1696
K D+ FL+DGS + + F+ + ++++ + +G+VQY +P F LK
Sbjct: 291 KIDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPLMGVVQYGDNPATHFNLKTH 350
Query: 1697 STKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQRVPQIAFVITGGKSV 1756
+ R + AI K+ +GG +N + + N F G+R P + V+ G
Sbjct: 351 TNSRDLKTAIEKITQRGGL-SNVGRAISFVTKNFFSKANGNR--SGAPNVVVVMVDGWPT 407
Query: 1757 EDAQDVSLALTQRGVKVFAVGVRN-IDSEEVGKIASNSATAFRVGNXXXXXXXXXXXXXX 1815
+ ++ S + G+ +F + + ++E+ + N A
Sbjct: 408 DKVEEASRLARESGINIFFITIEGAAENEKQYVVEPNFA-----NKAVCRTNGFYSLHVQ 462
Query: 1816 XHDAMHETLCPGV-----TD---AAKACNLDVILGF--DGSRDQNVFVAQKGFESKVDAI 1865
+H+TL P V TD +K C +GF DGS V F + + +
Sbjct: 463 SWFGLHKTLQPLVKRVCDTDRLACSKTCLNSADIGFVIDGSSS----VGTGNFRTVLQFV 518
Query: 1866 LNRISQMHRVSCSGGRSPTVRVSVVANTPSGPVEAFDFDEY--QPEMLEKFRNMRSQHPY 1923
N +++ +S R+ V T +E F FD+Y +P++L + +
Sbjct: 519 TN-LTKEFEIS-----DTDTRIGAVQYTYEQRLE-FGFDKYSSKPDILNAIKRVGYWSGG 571
Query: 1924 VLTEDTLKVYLNK-FRQSSPDSVKVVIHFTDGADGD 1958
T + L + F++S P+ K++I TDG D
Sbjct: 572 TSTGAAINFALEQLFKKSKPNKRKLMILITDGRSYD 607
Score = 42.2 bits (97), Expect = 0.090
Identities = 44/176 (25%), Positives = 80/176 (45%), Gaps = 25/176 (14%)
Query: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLDMSPDPKASQHFARVAVVQHAPSESVDN 2677
ID++F++D + + +F K+ +A + + LD+ P + VVQ+ DN
Sbjct: 292 IDLSFLIDGSTSIGKRRFRIQKQLLADVAQALDIGPAGPL------MGVVQYG-----DN 340
Query: 2678 ASMPPVKVEFSLTDYGSKEKLVDFLSRGMTQLQGTRALGSAIEYTIENVFESAPNPRD-- 2735
+ F+L + + L + + +TQ G +G AI + +N F A R
Sbjct: 341 PA-----THFNLKTHTNSRDLKTAIEK-ITQRGGLSNVGRAISFVTKNFFSKANGNRSGA 394
Query: 2736 LKIVVLMLTGEVPEQQLEEAQRVILQAKCKGYFFVVLGIGRKVNIKEVYTFASEPN 2791
+VV+M+ G P ++EEA R+ ++ +F + G N K+ + EPN
Sbjct: 395 PNVVVVMVDG-WPTDKVEEASRLARESGINIFFITIEGAAE--NEKQ---YVVEPN 444
>gb|AAD04919.1| (AF099154) von Willebrand factor [Canis familiaris]
Length = 2813
Score = 171 bits (428), Expect = 1e-40
Identities = 156/609 (25%), Positives = 280/609 (45%), Gaps = 48/609 (7%)
Query: 210 VGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLL 269
+G+ S V + P L D D++FL+DGS+ F V+ F+V ++
Sbjct: 1252 IGSTTSYVEDTPEPP-------LHDFHCSRLLDLVFLLDGSSKLSEDEFEVLKVFVVGMM 1304
Query: 270 EKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFV 329
E L I ++IRV VV++ D L +++ + +AG E+A+ L +
Sbjct: 1305 EHLHISQKRIRVAVVEYHDGSHAYIELKDRKRPSELRRITSQVKYAGSEVASTSEVLKYT 1364
Query: 330 VENHFTRAGGSRVEEGVPQVLVLISAGPSS---DEIRYGVVALKQASVFSF--GLGAQAA 384
+ F + R E +L++ S PS + +RY V LK+ V G+G A+
Sbjct: 1365 LFQIFGKI--DRPEASRIALLLMASQEPSRLARNLVRY-VQGLKKKKVIVIPVGIGPHAS 1421
Query: 385 -SRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQ------RHIVLKPPTIVTQ 437
+ L +N F +++++ Y+ +A +H + T+ ++
Sbjct: 1422 LKQIHLIEKQAPENKAFVFSGVDELEQRRDEIINYLCDLAPEAPAPTQHPPMAQVTVGSE 1481
Query: 438 VIEVN----KR-----DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQ 488
++ V+ KR D+VF+++GS +G ANFN R+F+ +VIQR+++GQD I V V Q
Sbjct: 1482 LLGVSSPGPKRNSMVLDVVFVLEGSDKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQ 1541
Query: 489 YADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEG 548
Y+ V E+ F+ +K EV+ VR ++ G+ TG AL ++ + F+ S G R E
Sbjct: 1542 YSYMVTVEYTFSEAQSKGEVLQQVRDIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQ 1599
Query: 549 IPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFI---- 604
+P L+ ++TG + DEI + +++ ++ +G A+ ELE+I + ++ + I
Sbjct: 1600 VPNLVYMVTGNPASDEIKRMPGDIQ---VVPIGVG-PHANVQELEKIGWPNAPILIHDFE 1655
Query: 605 --PAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFV 662
P E LQ G + TLS TP+ S D++ LLDGS+++ + F ++ F
Sbjct: 1656 MLPREAPDLVLQRCCSGEGLQIPTLSPTPDC-SQPLDVVLLLDGSSSIPASYFDEMKSFT 1714
Query: 663 MNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXXXXXXXXSA 722
++ +IG +V ++Q+ + N K + A
Sbjct: 1715 KAFISRANIGPRLTQVSVLQYGSITTIDVPWNVAYEKVHL-LSLVDLMQQEGGPSQIGDA 1773
Query: 723 LSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVG-ASQA 781
LS+ +E G+ R + +++L S DS AA A + F +G +
Sbjct: 1774 LSFAVRYVTSEVHGA--RPGASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIGDRY 1831
Query: 782 NKAELEQIA 790
++A+L +A
Sbjct: 1832 SEAQLSSLA 1840
Score = 145 bits (362), Expect = 8e-33
Identities = 144/591 (24%), Positives = 261/591 (43%), Gaps = 59/591 (9%)
Query: 817 TTYVSGGVEEVPLAQPESKR--DILFLFDGSANLV-GQFPVVRDFLYKIIDELNVKPEGT 873
T+YV E PL R D++FL DGS+ L +F V++ F+ +++ L++ +
Sbjct: 1256 TSYVED-TPEPPLHDFHCSRLLDLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRI 1314
Query: 874 RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 933
R+AV +Y D + + E+ + ++K + + L Y IF K
Sbjct: 1315 RVAVVEYHDGSHAYIELKDRKRPSELRRITSQVKYAGSEVASTSEVLKYTLFQIFGKIDR 1374
Query: 934 SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL----- 988
L + R + + LK+ V+ + A L+QI L
Sbjct: 1375 PEASRIALLLMASQEPSRLARNLVRYVQGLKKKKVI--VIPVGIGPHASLKQIHLIEKQA 1432
Query: 989 --SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS-------------------GE 1027
+ AF+ + + ++ +I+N L + APAP G
Sbjct: 1433 PENKAFVFSG--VDELEQRRDEIINYLCDLAPEAPAPTQHPPMAQVTVGSELLGVSSPGP 1490
Query: 1028 K------DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080
K DVVF+L+GS+ + + F +EF++ V++ +DVGQDR+ V V+QYS E+
Sbjct: 1491 KRNSMVLDVVFVLEGSDKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEY 1550
Query: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140
+ +K +V+ VR + GG NTG AL+++ + S G R E VP L+ ++T
Sbjct: 1551 TFSEAQSKGEVLQQVRDIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVT 1608
Query: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQL-GTVQQ 1199
+ + D+++ ++ VPIG+G +A++ E++ I + P+ + I F L
Sbjct: 1609 GNPASDEIKRMPGDIQ---VVPIGVG-PHANVQELEKIGW-PNAPILIHDFEMLPREAPD 1663
Query: 1200 VISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQS-AGPEFQYVRTLIERL 1258
++ +R ++ L P+P DVV L+DGS S F +++ +
Sbjct: 1664 LVLQRCCSGEGLQIPTLS------PTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAF 1717
Query: 1259 VDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEY 1318
+ ++G T+V+V+Q+ + N K + + V ++ +GG +G+AL +
Sbjct: 1718 ISRANIGPRLTQVSVLQYGSITTIDVPWNVAYEKVHLLSLVDLMQQEGGPS-QIGDALSF 1776
Query: 1319 VSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTI 1369
R + G+R G + +V++ + S D V A + V F I
Sbjct: 1777 AVRYVTSEVHGAR--PGASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPI 1825
Score = 136 bits (338), Expect = 5e-30
Identities = 132/587 (22%), Positives = 251/587 (42%), Gaps = 52/587 (8%)
Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
D++FL+D S + E+ F++++ F+ +++ L + + A+V+++ H L +
Sbjct: 1277 DLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRIRVAVVEYHDGSHAYIELKDRKR 1336
Query: 99 KQEVLSHISNMSYIGG-TNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDG 157
E+ S + Y G T + L+Y + K A ++ ++L
Sbjct: 1337 PSELRRITSQVKYAGSEVASTSEVLKYTLFQIFGKIDRPEAS----RIALLLMASQEPSR 1392
Query: 158 LALPSAE----LKSADVNVFAIGVEDADEGALKEI------ASEPLNMHMFNLENFTSLH 207
LA LK V V +G+ +LK+I A E ++
Sbjct: 1393 LARNLVRYVQGLKKKKVIVIPVGI--GPHASLKQIHLIEKQAPENKAFVFSGVDELEQRR 1450
Query: 208 DIVGNLVSCVHSSVSPERAGDTE--TLKDITAQDS---------------ADIIFLIDGS 250
D + N + ++PE T+ + +T D++F+++GS
Sbjct: 1451 DEIINYL----CDLAPEAPAPTQHPPMAQVTVGSELLGVSSPGPKRNSMVLDVVFVLEGS 1506
Query: 251 NNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVK 310
+ G NF +F+ +++++ +G +I V V+Q+S ++ +K +VL V+
Sbjct: 1507 DKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYTFSEAQSKGEVLQQVR 1566
Query: 311 ALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALK 370
+ + GG N GLAL ++ E+ F+ + G R E VP ++ +++ P+SDEI+
Sbjct: 1567 DIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVTGNPASDEIKR---MPG 1621
Query: 371 QASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLK 430
V G+G A+ EL+ I + + F L + ++ L+
Sbjct: 1622 DIQVVPIGVGPH-ANVQELEKIGWPNAPIL----IHDFEMLPREAPDLVLQRCCSGEGLQ 1676
Query: 431 PPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYA 490
PT+ D+V L+DGSS++ + F+ ++ F I R IG L QV+V QY
Sbjct: 1677 IPTLSPTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAFISRANIGPRLTQVSVLQYG 1736
Query: 491 DTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIP 550
+ +N K +++ V M+ +G G AL F + +S + A G
Sbjct: 1737 SITTIDVPWNVAYEKVHLLSLVDLMQQ-EGGPSQIGDALSFAVR--YVTSEVHGARPGAS 1793
Query: 551 KLLVLITGGKSLDEISQPAQELKRSSIMAFAIG-NKGADQAELEEIA 596
K +V++ S+D + A+ + + + F IG +A+L +A
Sbjct: 1794 KAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIGDRYSEAQLSSLA 1840
Score = 131 bits (326), Expect = 1e-28
Identities = 148/571 (25%), Positives = 239/571 (40%), Gaps = 62/571 (10%)
Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698
D++FLLDGS+ + + F ++ FV+ ++ L I IRV +V++ D L +
Sbjct: 1277 DLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRIRVAVVEYHDGSHAYIELKDRKR 1336
Query: 699 KSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED- 757
S++ L Y F G R ++ LLL A Q
Sbjct: 1337 PSELRRITSQVKYAGSEVASTSEVLKYTLFQIF----GKIDRPEASRIALLLMASQEPSR 1392
Query: 758 ---SYLQAANALTRAGILTFCVGASQANKAELEQIAF-------NPSLVYL--------M 799
+ ++ L + ++ VG A L+QI N + V+
Sbjct: 1393 LARNLVRYVQGLKKKKVIVIPVGIGP--HASLKQIHLIEKQAPENKAFVFSGVDELEQRR 1450
Query: 800 DDFSSXXXXXXXXXXXXTTY-----VSGGVEEVPLAQPESKR-----DILFLFDGSANL- 848
D+ + T + V+ G E + ++ P KR D++F+ +GS +
Sbjct: 1451 DEIINYLCDLAPEAPAPTQHPPMAQVTVGSELLGVSSPGPKRNSMVLDVVFVLEGSDKIG 1510
Query: 849 VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKI 908
F R+F+ ++I ++V + + V QYS V VE F E QSK E+L V+ ++
Sbjct: 1511 EANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYTFSEAQSKGEVLQQVRDIRY 1570
Query: 909 KTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGR-SSDRVDGPASNLKQSG 967
+ G N G AL Y + F S G R + + LV +V G +SD + +++
Sbjct: 1571 RGGNRTNTGLALQYLSEHSFSVSQGDREQ---VPNLVYMVTGNPASDEIKRMPGDIQ--- 1624
Query: 968 VVPFIFQAKNADPAELEQIVL--SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPV- 1024
VVP I +A+ ELE+I +P I E LP+ P +V G P
Sbjct: 1625 VVP-IGVGPHANVQELEKIGWPNAPILIHDFEMLPREA---PDLVLQRCCSGEGLQIPTL 1680
Query: 1025 ------SGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTR 1077
S DVV LLDGS + S F +K F + + ++G +V+V+QY T
Sbjct: 1681 SPTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAFISRANIGPRLTQVSVLQYGSITT 1740
Query: 1078 PEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLI 1137
+ N K +++ V + GGP+ G AL F +R + G+R G + ++
Sbjct: 1741 IDVPWNVAYEKVHLLSLVDLMQQEGGPS-QIGDALSFAVRYVTSEVHGAR--PGASKAVV 1797
Query: 1138 VLTADRSGDDVRNPSVVVK--RGGAVPIGIG 1166
+L D S D V + + R PIGIG
Sbjct: 1798 ILVTDVSVDSVDAAAEAARSNRVTVFPIGIG 1828
Score = 130 bits (324), Expect = 2e-28
Identities = 134/582 (23%), Positives = 241/582 (41%), Gaps = 55/582 (9%)
Query: 1233 DVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSS 1291
D+VFL+DGS EF+ ++ + ++++L + RVAV+++ D A L
Sbjct: 1277 DLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRIRVAVVEYHDGSHAYIELKDRKR 1336
Query: 1292 KDEVQNAVQRLRPKGGRQINVGNALEYVSRNIF---KRPLGSRIEEGVPQFLVLISSGKS 1348
E++ +++ G + L+Y IF RP SRI L+L++S +
Sbjct: 1337 PSELRRITSQVKYAGSEVASTSEVLKYTLFQIFGKIDRPEASRIA------LLLMASQEP 1390
Query: 1349 DDEV-----VVPAVELKQFGVAPFTIARNAD--QEELVKISLSPEYVFSVSTFRELPSLE 1401
V ++ K+ V P I +A Q L++ F S EL
Sbjct: 1391 SRLARNLVRYVQGLKKKKVIVIPVGIGPHASLKQIHLIEKQAPENKAFVFSGVDELEQRR 1450
Query: 1402 QKLLTPITTLTSEQIQKLLASTRYPP-----------------PAVESDAADIVFLIDSS 1444
+++ + L E A T++PP P S D+VF+++ S
Sbjct: 1451 DEIINYLCDLAPEAP----APTQHPPMAQVTVGSELLGVSSPGPKRNSMVLDVVFVLEGS 1506
Query: 1445 EGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIR 1504
+ + F R+F+ +++R+++G ++ V V+Q+S V E+ +S+ VL +R
Sbjct: 1507 DKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYTFSEAQSKGEVLQQVR 1566
Query: 1505 RLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIR 1564
+R RGG+ NTG AL++++ + F S G R + VP + +V G + D++ R I+
Sbjct: 1567 DIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVTGNPASDEIKRMPGDIQ 1624
Query: 1565 SSGIVSLGVGDR-NIDRTELQTITNDPRLVFTVREFRELP-NIEERIMNSFGPSXXXXXX 1622
+V +GVG N+ E N P L + +F LP + ++
Sbjct: 1625 ---VVPIGVGPHANVQELEKIGWPNAPIL---IHDFEMLPREAPDLVLQRCCSGEGLQIP 1678
Query: 1623 XXXXXXXXSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQ 1682
S+P D+V LLDGS + F E+ F + QV ++Q
Sbjct: 1679 TLSPTPDCSQP----LDVVLLLDGSSSIPASYFDEMKSFTKAFISRANIGPRLTQVSVLQ 1734
Query: 1683 YNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQR 1742
Y S T + K ++ ++ + +GG +++G +V
Sbjct: 1735 YGSITTIDVPWNVAYEKVHLLSLVDLMQQEGG---PSQIGDALSFAVRYVTSEVHGARPG 1791
Query: 1743 VPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSE 1784
+ ++ SV+ + A V VF +G+ + SE
Sbjct: 1792 ASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIGDRYSE 1833
Score = 94.0 bits (230), Expect = 2e-17
Identities = 88/367 (23%), Positives = 166/367 (44%), Gaps = 24/367 (6%)
Query: 33 KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFL 92
+N D++F+++ S IGE +F REF+ +V++ + VG++ H ++Q++ E+
Sbjct: 1492 RNSMVLDVVFVLEGSDKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYT 1551
Query: 93 LNTYRTKQEVLSHISNMSYIGGT-NQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTD 151
+ ++K EVL + ++ Y GG TG L+Y+ + + + G R + VP ++ ++T
Sbjct: 1552 FSEAQSKGEVLQQVRDIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVTG 1609
Query: 152 GHSKDGLALPSAELKSADVNVFAIGV-EDADEGALKEIA--SEPLNMHMFNLENFTSLHD 208
+ D + + D+ V IGV A+ L++I + P+ +H +F L
Sbjct: 1610 NPASDEI-----KRMPGDIQVVPIGVGPHANVQELEKIGWPNAPILIH-----DFEMLPR 1659
Query: 209 IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268
+LV + S E D++ L+DGS++ + F + F
Sbjct: 1660 EAPDLV--LQRCCSGEGLQIPTLSPTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAF 1717
Query: 269 LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328
+ + IG + +V V+Q+ + K +L V + GG + IG AL F
Sbjct: 1718 ISRANIGPRLTQVSVLQYGSITTIDVPWNVAYEKVHLLSLVDLMQQEGGP-SQIGDALSF 1776
Query: 329 VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALK--QASVFSFGLGAQAASR 386
V + G+R G + +V++ S D + A + + +VF G+G S
Sbjct: 1777 AVRYVTSEVHGAR--PGASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIG-DRYSE 1833
Query: 387 AELQHIA 393
A+L +A
Sbjct: 1834 AQLSSLA 1840
>gb|AAB93766.1| (U66246) von Willebrand factor [Canis familiaris]
Length = 2813
Score = 171 bits (428), Expect = 1e-40
Identities = 156/609 (25%), Positives = 280/609 (45%), Gaps = 48/609 (7%)
Query: 210 VGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNLL 269
+G+ S V + P L D D++FL+DGS+ F V+ F+V ++
Sbjct: 1252 IGSTTSYVEDTPEPP-------LHDFHCSRLLDLVFLLDGSSKLSEDEFEVLKVFVVGMM 1304
Query: 270 EKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDFV 329
E L I ++IRV VV++ D L +++ + +AG E+A+ L +
Sbjct: 1305 EHLHISQKRIRVAVVEYHDGSHAYIELKDRKRPSELRRITSQVKYAGSEVASTSEVLKYT 1364
Query: 330 VENHFTRAGGSRVEEGVPQVLVLISAGPSS---DEIRYGVVALKQASVFSF--GLGAQAA 384
+ F + R E +L++ S PS + +RY V LK+ V G+G A+
Sbjct: 1365 LFQIFGKI--DRPEASRIALLLMASQEPSRLARNLVRY-VQGLKKKKVIVIPVGIGPHAS 1421
Query: 385 -SRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQ------RHIVLKPPTIVTQ 437
+ L +N F +++++ Y+ +A +H + T+ ++
Sbjct: 1422 LKQIHLIEKQAPENKAFVFSGVDELEQRRDEIINYLCDLAPEAPAPTQHPPMAQVTVGSE 1481
Query: 438 VIEVN----KR-----DIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQ 488
++ V+ KR D+VF+++GS +G ANFN R+F+ +VIQR+++GQD I V V Q
Sbjct: 1482 LLGVSSPGPKRNSMVLDVVFVLEGSDKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQ 1541
Query: 489 YADTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEG 548
Y+ V E+ F+ +K EV+ VR ++ G+ TG AL ++ + F+ S G R E
Sbjct: 1542 YSYMVTVEYTFSEAQSKGEVLQQVRDIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQ 1599
Query: 549 IPKLLVLITGGKSLDEISQPAQELKRSSIMAFAIGNKGADQAELEEIAFDSSLVFI---- 604
+P L+ ++TG + DEI + +++ ++ +G A+ ELE+I + ++ + I
Sbjct: 1600 VPNLVYMVTGNPASDEIKRMPGDIQ---VVPIGVG-PHANVQELEKIGWPNAPILIHDFE 1655
Query: 605 --PAEFRAAPLQGMLPGLLAPLRTLSGTPEVHSNKRDIIFLLDGSANVGKTNFPYVRDFV 662
P E LQ G + TLS TP+ S D++ LLDGS+++ + F ++ F
Sbjct: 1656 MLPREAPDLVLQRCCSGEGLQIPTLSPTPDC-SQPLDVVLLLDGSSSIPASYFDEMKSFT 1714
Query: 663 MNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQTKSDIXXXXXXXXXXXXXXXXXXSA 722
++ +IG +V ++Q+ + N K + A
Sbjct: 1715 KAFISRANIGPRLTQVSVLQYGSITTIDVPWNVAYEKVHL-LSLVDLMQQEGGPSQIGDA 1773
Query: 723 LSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSEDSYLQAANALTRAGILTFCVG-ASQA 781
LS+ +E G+ R + +++L S DS AA A + F +G +
Sbjct: 1774 LSFAVRYVTSEVHGA--RPGASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIGDRY 1831
Query: 782 NKAELEQIA 790
++A+L +A
Sbjct: 1832 SEAQLSSLA 1840
Score = 145 bits (362), Expect = 8e-33
Identities = 144/591 (24%), Positives = 261/591 (43%), Gaps = 59/591 (9%)
Query: 817 TTYVSGGVEEVPLAQPESKR--DILFLFDGSANLV-GQFPVVRDFLYKIIDELNVKPEGT 873
T+YV E PL R D++FL DGS+ L +F V++ F+ +++ L++ +
Sbjct: 1256 TSYVED-TPEPPLHDFHCSRLLDLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRI 1314
Query: 874 RIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKIKTGKALNLGYALDYAQRYIFVKSAG 933
R+AV +Y D + + E+ + ++K + + L Y IF K
Sbjct: 1315 RVAVVEYHDGSHAYIELKDRKRPSELRRITSQVKYAGSEVASTSEVLKYTLFQIFGKIDR 1374
Query: 934 SRIEDGVLQFLVLLVAGRSSDRVDGPASNLKQSGVVPFIFQAKNADPAELEQIVL----- 988
L + R + + LK+ V+ + A L+QI L
Sbjct: 1375 PEASRIALLLMASQEPSRLARNLVRYVQGLKKKKVI--VIPVGIGPHASLKQIHLIEKQA 1432
Query: 989 --SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPVS-------------------GE 1027
+ AF+ + + ++ +I+N L + APAP G
Sbjct: 1433 PENKAFVFSG--VDELEQRRDEIINYLCDLAPEAPAPTQHPPMAQVTVGSELLGVSSPGP 1490
Query: 1028 K------DVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTRPEF 1080
K DVVF+L+GS+ + + F +EF++ V++ +DVGQDR+ V V+QYS E+
Sbjct: 1491 KRNSMVLDVVFVLEGSDKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEY 1550
Query: 1081 YLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLIVLT 1140
+ +K +V+ VR + GG NTG AL+++ + S G R E VP L+ ++T
Sbjct: 1551 TFSEAQSKGEVLQQVRDIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVT 1608
Query: 1141 ADRSGDDVRNPSVVVKRGGAVPIGIGIGNADITEMQTISFIPDFAVAIPTFRQL-GTVQQ 1199
+ + D+++ ++ VPIG+G +A++ E++ I + P+ + I F L
Sbjct: 1609 GNPASDEIKRMPGDIQ---VVPIGVG-PHANVQELEKIGW-PNAPILIHDFEMLPREAPD 1663
Query: 1200 VISERVTQLTREELSRLQPVLQPLPSPGVGGKRDVVFLIDGSQS-AGPEFQYVRTLIERL 1258
++ +R ++ L P+P DVV L+DGS S F +++ +
Sbjct: 1664 LVLQRCCSGEGLQIPTLS------PTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAF 1717
Query: 1259 VDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEY 1318
+ ++G T+V+V+Q+ + N K + + V ++ +GG +G+AL +
Sbjct: 1718 ISRANIGPRLTQVSVLQYGSITTIDVPWNVAYEKVHLLSLVDLMQQEGGPS-QIGDALSF 1776
Query: 1319 VSRNIFKRPLGSRIEEGVPQFLVLISSGKSDDEVVVPAVELKQFGVAPFTI 1369
R + G+R G + +V++ + S D V A + V F I
Sbjct: 1777 AVRYVTSEVHGAR--PGASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPI 1825
Score = 136 bits (338), Expect = 5e-30
Identities = 132/587 (22%), Positives = 251/587 (42%), Gaps = 52/587 (8%)
Query: 39 DIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFLLNTYRT 98
D++FL+D S + E+ F++++ F+ +++ L + + A+V+++ H L +
Sbjct: 1277 DLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRIRVAVVEYHDGSHAYIELKDRKR 1336
Query: 99 KQEVLSHISNMSYIGG-TNQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTDGHSKDG 157
E+ S + Y G T + L+Y + K A ++ ++L
Sbjct: 1337 PSELRRITSQVKYAGSEVASTSEVLKYTLFQIFGKIDRPEAS----RIALLLMASQEPSR 1392
Query: 158 LALPSAE----LKSADVNVFAIGVEDADEGALKEI------ASEPLNMHMFNLENFTSLH 207
LA LK V V +G+ +LK+I A E ++
Sbjct: 1393 LARNLVRYVQGLKKKKVIVIPVGI--GPHASLKQIHLIEKQAPENKAFVFSGVDELEQRR 1450
Query: 208 DIVGNLVSCVHSSVSPERAGDTE--TLKDITAQDS---------------ADIIFLIDGS 250
D + N + ++PE T+ + +T D++F+++GS
Sbjct: 1451 DEIINYL----CDLAPEAPAPTQHPPMAQVTVGSELLGVSSPGPKRNSMVLDVVFVLEGS 1506
Query: 251 NNTGSVNFAVILDFLVNLLEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVK 310
+ G NF +F+ +++++ +G +I V V+Q+S ++ +K +VL V+
Sbjct: 1507 DKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYTFSEAQSKGEVLQQVR 1566
Query: 311 ALGFAGGELANIGLALDFVVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALK 370
+ + GG N GLAL ++ E+ F+ + G R E VP ++ +++ P+SDEI+
Sbjct: 1567 DIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVTGNPASDEIKR---MPG 1621
Query: 371 QASVFSFGLGAQAASRAELQHIATDDNLVFTVPEFRSFGDLQEKLLPYIVGVAQRHIVLK 430
V G+G A+ EL+ I + + F L + ++ L+
Sbjct: 1622 DIQVVPIGVGPH-ANVQELEKIGWPNAPIL----IHDFEMLPREAPDLVLQRCCSGEGLQ 1676
Query: 431 PPTIVTQVIEVNKRDIVFLVDGSSALGLANFNAIRDFIAKVIQRLEIGQDLIQVAVAQYA 490
PT+ D+V L+DGSS++ + F+ ++ F I R IG L QV+V QY
Sbjct: 1677 IPTLSPTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAFISRANIGPRLTQVSVLQYG 1736
Query: 491 DTVRPEFYFNTHPTKREVITAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIP 550
+ +N K +++ V M+ +G G AL F + +S + A G
Sbjct: 1737 SITTIDVPWNVAYEKVHLLSLVDLMQQ-EGGPSQIGDALSFAVR--YVTSEVHGARPGAS 1793
Query: 551 KLLVLITGGKSLDEISQPAQELKRSSIMAFAIG-NKGADQAELEEIA 596
K +V++ S+D + A+ + + + F IG +A+L +A
Sbjct: 1794 KAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIGDRYSEAQLSSLA 1840
Score = 131 bits (326), Expect = 1e-28
Identities = 148/571 (25%), Positives = 239/571 (40%), Gaps = 62/571 (10%)
Query: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLDIGNDNIRVGLVQFSDTPVTEFSLNTYQT 698
D++FLLDGS+ + + F ++ FV+ ++ L I IRV +V++ D L +
Sbjct: 1277 DLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRIRVAVVEYHDGSHAYIELKDRKR 1336
Query: 699 KSDIXXXXXXXXXXXXXXXXXXSALSYVYANHFTEAGGSRIREHVPQLLLLLTAGQSED- 757
S++ L Y F G R ++ LLL A Q
Sbjct: 1337 PSELRRITSQVKYAGSEVASTSEVLKYTLFQIF----GKIDRPEASRIALLLMASQEPSR 1392
Query: 758 ---SYLQAANALTRAGILTFCVGASQANKAELEQIAF-------NPSLVYL--------M 799
+ ++ L + ++ VG A L+QI N + V+
Sbjct: 1393 LARNLVRYVQGLKKKKVIVIPVGIGP--HASLKQIHLIEKQAPENKAFVFSGVDELEQRR 1450
Query: 800 DDFSSXXXXXXXXXXXXTTY-----VSGGVEEVPLAQPESKR-----DILFLFDGSANL- 848
D+ + T + V+ G E + ++ P KR D++F+ +GS +
Sbjct: 1451 DEIINYLCDLAPEAPAPTQHPPMAQVTVGSELLGVSSPGPKRNSMVLDVVFVLEGSDKIG 1510
Query: 849 VGQFPVVRDFLYKIIDELNVKPEGTRIAVAQYSDDVKVESRFDEHQSKPEILNLVKRMKI 908
F R+F+ ++I ++V + + V QYS V VE F E QSK E+L V+ ++
Sbjct: 1511 EANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYTFSEAQSKGEVLQQVRDIRY 1570
Query: 909 KTGKALNLGYALDYAQRYIFVKSAGSRIEDGVLQFLVLLVAGR-SSDRVDGPASNLKQSG 967
+ G N G AL Y + F S G R + + LV +V G +SD + +++
Sbjct: 1571 RGGNRTNTGLALQYLSEHSFSVSQGDREQ---VPNLVYMVTGNPASDEIKRMPGDIQ--- 1624
Query: 968 VVPFIFQAKNADPAELEQIVL--SPAFILAAESLPKIGDLHPQIVNLLKSVHNGAPAPV- 1024
VVP I +A+ ELE+I +P I E LP+ P +V G P
Sbjct: 1625 VVP-IGVGPHANVQELEKIGWPNAPILIHDFEMLPREA---PDLVLQRCCSGEGLQIPTL 1680
Query: 1025 ------SGEKDVVFLLDGSEGV-RSGFPLLKEFVQRVVESLDVGQDRVRVAVVQYSDRTR 1077
S DVV LLDGS + S F +K F + + ++G +V+V+QY T
Sbjct: 1681 SPTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAFISRANIGPRLTQVSVLQYGSITT 1740
Query: 1078 PEFYLNSYMNKQDVVNAVRQLTLLGGPTPNTGAALEFVLRNILVSSAGSRITEGVPQLLI 1137
+ N K +++ V + GGP+ G AL F +R + G+R G + ++
Sbjct: 1741 IDVPWNVAYEKVHLLSLVDLMQQEGGPS-QIGDALSFAVRYVTSEVHGAR--PGASKAVV 1797
Query: 1138 VLTADRSGDDVRNPSVVVK--RGGAVPIGIG 1166
+L D S D V + + R PIGIG
Sbjct: 1798 ILVTDVSVDSVDAAAEAARSNRVTVFPIGIG 1828
Score = 130 bits (324), Expect = 2e-28
Identities = 134/582 (23%), Positives = 241/582 (41%), Gaps = 55/582 (9%)
Query: 1233 DVVFLIDGSQSAGP-EFQYVRTLIERLVDYLDVGFDTTRVAVIQFSDDPKAEFLLNAHSS 1291
D+VFL+DGS EF+ ++ + ++++L + RVAV+++ D A L
Sbjct: 1277 DLVFLLDGSSKLSEDEFEVLKVFVVGMMEHLHISQKRIRVAVVEYHDGSHAYIELKDRKR 1336
Query: 1292 KDEVQNAVQRLRPKGGRQINVGNALEYVSRNIF---KRPLGSRIEEGVPQFLVLISSGKS 1348
E++ +++ G + L+Y IF RP SRI L+L++S +
Sbjct: 1337 PSELRRITSQVKYAGSEVASTSEVLKYTLFQIFGKIDRPEASRIA------LLLMASQEP 1390
Query: 1349 DDEV-----VVPAVELKQFGVAPFTIARNAD--QEELVKISLSPEYVFSVSTFRELPSLE 1401
V ++ K+ V P I +A Q L++ F S EL
Sbjct: 1391 SRLARNLVRYVQGLKKKKVIVIPVGIGPHASLKQIHLIEKQAPENKAFVFSGVDELEQRR 1450
Query: 1402 QKLLTPITTLTSEQIQKLLASTRYPP-----------------PAVESDAADIVFLIDSS 1444
+++ + L E A T++PP P S D+VF+++ S
Sbjct: 1451 DEIINYLCDLAPEAP----APTQHPPMAQVTVGSELLGVSSPGPKRNSMVLDVVFVLEGS 1506
Query: 1445 EGVRPDGFAHIRDFVSRIVRRLNIGPSKVRVGVVQFSNDVFPEFYLKTYRSQAPVLDAIR 1504
+ + F R+F+ +++R+++G ++ V V+Q+S V E+ +S+ VL +R
Sbjct: 1507 DKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYTFSEAQSKGEVLQQVR 1566
Query: 1505 RLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHLVLVLGGKSQDDVSRFAQVIR 1564
+R RGG+ NTG AL++++ + F S G R + VP + +V G + D++ R I+
Sbjct: 1567 DIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVTGNPASDEIKRMPGDIQ 1624
Query: 1565 SSGIVSLGVGDR-NIDRTELQTITNDPRLVFTVREFRELP-NIEERIMNSFGPSXXXXXX 1622
+V +GVG N+ E N P L + +F LP + ++
Sbjct: 1625 ---VVPIGVGPHANVQELEKIGWPNAPIL---IHDFEMLPREAPDLVLQRCCSGEGLQIP 1678
Query: 1623 XXXXXXXXSRPEKKKADIVFLLDGSINFRRDSFQEVLRFVSEIVDTVYEDGDSIQVGLVQ 1682
S+P D+V LLDGS + F E+ F + QV ++Q
Sbjct: 1679 TLSPTPDCSQP----LDVVLLLDGSSSIPASYFDEMKSFTKAFISRANIGPRLTQVSVLQ 1734
Query: 1683 YNSDPTDEFFLKDFSTKRQIIDAINKVVYKGGRHANTKVGLEHLRVNHFVPEAGSRLDQR 1742
Y S T + K ++ ++ + +GG +++G +V
Sbjct: 1735 YGSITTIDVPWNVAYEKVHLLSLVDLMQQEGG---PSQIGDALSFAVRYVTSEVHGARPG 1791
Query: 1743 VPQIAFVITGGKSVEDAQDVSLALTQRGVKVFAVGVRNIDSE 1784
+ ++ SV+ + A V VF +G+ + SE
Sbjct: 1792 ASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIGDRYSE 1833
Score = 94.0 bits (230), Expect = 2e-17
Identities = 88/367 (23%), Positives = 166/367 (44%), Gaps = 24/367 (6%)
Query: 33 KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAVGENDFHFALVQFNGNPHTEFL 92
+N D++F+++ S IGE +F REF+ +V++ + VG++ H ++Q++ E+
Sbjct: 1492 RNSMVLDVVFVLEGSDKIGEANFNKSREFMEEVIQRMDVGQDRIHVTVLQYSYMVTVEYT 1551
Query: 93 LNTYRTKQEVLSHISNMSYIGGT-NQTGKGLEYIMQSHLTKAAGSRAGDGVPQVIVVLTD 151
+ ++K EVL + ++ Y GG TG L+Y+ + + + G R + VP ++ ++T
Sbjct: 1552 FSEAQSKGEVLQQVRDIRYRGGNRTNTGLALQYLSEHSFSVSQGDR--EQVPNLVYMVTG 1609
Query: 152 GHSKDGLALPSAELKSADVNVFAIGV-EDADEGALKEIA--SEPLNMHMFNLENFTSLHD 208
+ D + + D+ V IGV A+ L++I + P+ +H +F L
Sbjct: 1610 NPASDEI-----KRMPGDIQVVPIGVGPHANVQELEKIGWPNAPILIH-----DFEMLPR 1659
Query: 209 IVGNLVSCVHSSVSPERAGDTETLKDITAQDSADIIFLIDGSNNTGSVNFAVILDFLVNL 268
+LV + S E D++ L+DGS++ + F + F
Sbjct: 1660 EAPDLV--LQRCCSGEGLQIPTLSPTPDCSQPLDVVLLLDGSSSIPASYFDEMKSFTKAF 1717
Query: 269 LEKLPIGTQQIRVGVVQFSDEPRTMFSLDTYSTKAQVLGAVKALGFAGGELANIGLALDF 328
+ + IG + +V V+Q+ + K +L V + GG + IG AL F
Sbjct: 1718 ISRANIGPRLTQVSVLQYGSITTIDVPWNVAYEKVHLLSLVDLMQQEGGP-SQIGDALSF 1776
Query: 329 VVENHFTRAGGSRVEEGVPQVLVLISAGPSSDEIRYGVVALK--QASVFSFGLGAQAASR 386
V + G+R G + +V++ S D + A + + +VF G+G S
Sbjct: 1777 AVRYVTSEVHGAR--PGASKAVVILVTDVSVDSVDAAAEAARSNRVTVFPIGIG-DRYSE 1833
Query: 387 AELQHIA 393
A+L +A
Sbjct: 1834 AQLSSLA 1840
