Score E
Sequences producing significant alignments: (bits) Value
ref|NP_065137.1| tumor endothelial marker 1 precursor [Homo... 1426 0.0
pir||THHUB thrombomodulin precursor - human >gi|220127|dbj|... 201 3e-50
ref|NP_000352.1| thrombomodulin [Homo sapiens] >gi|136170|s... 201 3e-50
gb|AAB27209.1| thrombomodulin [human, urine, Peptide, 468 aa] 197 5e-49
ref|NP_034870.1| lymphocyte antigen 68 [Mus musculus] >gi|3... 182 2e-44
gb|AAG01572.1|AF136537_1 (AF136537) C1q/MBL/SPA receptor C1... 181 2e-44
gb|AAF80402.1|AF160978_1 (AF160978) C1qRp [Rattus norvegicus] 181 2e-44
ref|NP_033404.1| thrombomodulin [Mus musculus] >gi|136171|s... 181 2e-44
emb|CAC00597.1| (AL118508) dJ737E23.1 (EGF-like domains con... 179 1e-43
ref|NP_036204.1| complement component C1q receptor [Homo sa... 178 1e-43
gb|AAB80760.1| (AF022743) thrombomodulin [Rattus norvegicus] 178 2e-43
sp|P06579|TRBM_BOVIN THROMBOMODULIN (FETOMODULIN) (TM) >gi|... 102 1e-20
gb|AAB49723.1| (U90121) thrombomdulin [artificial sequence] 99 2e-19
pir||T27283 hypothetical protein Y64G10A.f - Caenorhabditis... 98 5e-19
emb|CAB57911.1| (AL110498) contains similarity to Pfam doma... 98 5e-19
pir||S78040 fibulin, splice form C precursor - mouse 94 4e-18
pir||S34968 fibulin, splice form D precursor - mouse 94 4e-18
ref|NP_034310.1| fibulin 1; BM-90/fibulin extracellular mat... 94 4e-18
ref|XP_001220.1| fibulin 1 isoform D [Homo sapiens] 93 9e-18
ref|XP_001221.1| fibulin 1 isoform B precursor [Homo sapiens] 93 9e-18
ref|XP_001224.1| fibulin 1 isoform C precursor [Homo sapiens] 93 9e-18
ref|XP_001222.1| fibulin 1 [Homo sapiens] 93 9e-18
gb|AAG17241.1|AF217999_1 (AF217999) unknown [Homo sapiens] 93 9e-18
ref|NP_006477.1| fibulin 1 isoform A precursor [Homo sapien... 93 9e-18
ref|NP_001987.1| fibulin 1 isoform A precursor [Homo sapien... 93 9e-18
ref|NP_006476.1| fibulin 1 isoform A precursor [Homo sapien... 93 9e-18
ref|NP_006478.1| fibulin 1 isoform A precursor [Homo sapien... 93 9e-18
emb|CAB46380.1| (AL021578) dJ453C12.3 (matrilin-4) [Homo sa... 93 1e-17
pir||T13954 MEGF6 protein - rat >gi|3449294|dbj|BAA32462.1|... 92 2e-17
sp|O73775|FBL1_CHICK FIBULIN-1 PRECURSOR >gi|2947316|gb|AAC... 92 2e-17
gb|AAC05387.1| (AF051399) fibulin-1, isoform D precursor [G... 92 2e-17
gb|AAG25939.1|AF276425_1 (AF276425) EGF-related protein SCU... 91 4e-17
gb|AAD34456.1| (AF135253) fibulin-2 [Mus musculus] 91 4e-17
ref|NP_032018.1| fibulin 2 [Mus musculus] >gi|585122|sp|P37... 91 4e-17
emb|CAB43267.1| (AL050095) hypothetical protein [Homo sapiens] 90 1e-16
ref|NP_001989.1| fibulin 2 precursor; Fibulin-2 [Homo sapie... 90 1e-16
emb|CAB62995.1| (Z98047) dJ162H14.1 (Fibulin 1) [Homo sapiens] 89 2e-16
ref|NP_058042.1| matrilin 2 [Mus musculus] >gi|7387906|sp|O... 89 2e-16
gb|AAB80944.1| (AF013751) fibulin-1 D [Danio rerio] 87 9e-16
gb|AAD41769.1|AF112153_1 (AF112153) developmental arteries ... 85 3e-15
ref|NP_035942.1| fibulin 5 [Mus musculus] >gi|9973193|sp|Q9... 85 3e-15
ref|NP_066025.1| CEGP1 protein [Homo sapiens] >gi|8052237|e... 83 1e-14
emb|CAB70853.1| (AL137638) hypothetical protein [Homo sapiens] 82 2e-14
ref|NP_062026.1| fibulin 5 [Rattus norvegicus] >gi|4583509|... 82 2e-14
emb|CAB38568.1| (AJ133490) fibulin-5 [Homo sapiens] >gi|530... 82 2e-14
pir||T22793 hypothetical protein F56H11.1 - Caenorhabditis ... 82 3e-14
gb|AAC28322.1| (AF051402) fibulin-1 isoform C precursor [Ca... 82 3e-14
gb|AAC28321.1| (AF051401) fibulin-1 isoform D precursor [Ca... 82 3e-14
gb|AAC24035.1| (AF070477) fibulin-1D precursor [Caenorhabdi... 82 3e-14
ref|NP_006320.1| fibulin 5; urine p50 protein; developmenta... 81 4e-14
>ref|NP_065137.1| tumor endothelial marker 1 precursor [Homo sapiens]
gb|AAG00867.1|AF279142_1 (AF279142) tumor endothelial marker 1 precursor [Homo sapiens]
Length = 757
Score = 1426 bits (3652), Expect = 0.0
Identities = 669/745 (89%), Positives = 669/745 (89%)
Query: 13 GPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDS 72
GPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDS
Sbjct: 13 GPTLGQDPWAAEPRAACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDS 72
Query: 73 LVGAGPASRLLWIGXXXXXXXXXXXXXXXGFTWTTGDQDTAFTNWAQPASGGPCPAQRCV 132
LVGAGPASRLLWIG GFTWTTGDQDTAFTNWAQPASGGPCPAQRCV
Sbjct: 73 LVGAGPASRLLWIGLQRQARQCQLQRPLRGFTWTTGDQDTAFTNWAQPASGGPCPAQRCV 132
Query: 133 ALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEW 192
ALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEW
Sbjct: 133 ALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEW 192
Query: 193 LPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDG 252
LPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDG
Sbjct: 193 LPFGSVAAVQCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDG 252
Query: 253 HVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVD 312
HVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVD
Sbjct: 253 HVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVD 312
Query: 313 TDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQXXXXXXXXXX 372
TDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQ
Sbjct: 313 TDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAGAMGAQASQDLGDELLDDG 372
Query: 373 XXXXXXXXAWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPP 432
AWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPP
Sbjct: 373 EDEEDEDEAWKAFNGGWTEMPGILWMEPTQPPDFALAYRPSFPEDREPQIPYPEPTWPPP 432
Query: 433 LSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDL 492
LSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDL
Sbjct: 433 LSAPRVPYHSSVLSVTRPVVVSATHPTLPSAHQPPVIPATHPALSRDHQIPVIAANYPDL 492
Query: 493 PSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPP 552
PSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPP
Sbjct: 493 PSAYQPGILSVSHSAQPPAHQPPMISTKYPELFPAHQSPMFPDTRVAGTQTTTHLPGIPP 552
Query: 553 NHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISVXXXX 612
NHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISV
Sbjct: 553 NHAPLVTTLGAQLPPQAPDALVLRTQATQLPIIPTAQPSLTTTSRSPVSPAHQISVPAAT 612
Query: 613 XXXXXXXXXXXXXXXNQTSPISPTHPHSKAPQIPREDGPSPKXXXXXXXXXXXXXXXXXX 672
NQTSPISPTHPHSKAPQIPREDGPSPK
Sbjct: 613 QPAALPTLLPSQSPTNQTSPISPTHPHSKAPQIPREDGPSPKLALWLPSPAPTAAPTALG 672
Query: 673 XXXXXXHSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNKRITDCYRWVIHA 732
HSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNKRITDCYRWVIHA
Sbjct: 673 EAGLAEHSQRDDRWLLVALLVPTCVFLVVLLALGIVYCTRCGPHAPNKRITDCYRWVIHA 732
Query: 733 GSKSPTEPMPPRGSLTGVQTCRTSV 757
GSKSPTEPMPPRGSLTGVQTCRTSV
Sbjct: 733 GSKSPTEPMPPRGSLTGVQTCRTSV 757
>pir||THHUB thrombomodulin precursor - human
dbj|BAA00149.1| (D00210) thrombomodulin precursor [Homo sapiens]
emb|CAA29045.1| (X05495) thrombomodulin [Homo sapiens]
prf||1403353A thrombomodulin [Homo sapiens]
Length = 575
Score = 201 bits (505), Expect = 3e-50
Identities = 135/357 (37%), Positives = 168/357 (46%), Gaps = 33/357 (9%)
Query: 20 PWAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGA 76
P AEP+ + C C+AL+P TFL A + C L G L T R+ A + L+
Sbjct: 18 PAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNG 77
Query: 77 --GPASRLLWIGXXX--XXXXXXXXXXXXGFTWTTGDQDTAFTNWAQ-PASGGPCPAQRC 131
G R LWIG GF W TGD +T+++ WA+ +G P C
Sbjct: 78 DGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLC 137
Query: 132 VALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAV---YTTPF 183
VA+ A+ E W E C + DG+LC+F F C L E G A AV Y TPF
Sbjct: 138 VAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITYGTPF 197
Query: 184 HLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVG-WSRAGPLCLGTGCSPDNGGC 242
+F+ LP GS AAV A G L+C P G W+R P CS +NGGC
Sbjct: 198 AARGADFQALPVGSSAAV---APLGLQLMCTAPPGAVQGHWAREAP--GAWDCSVENGGC 252
Query: 243 EHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGGPQGYSCHC 296
EH C + G C+C G L ADGRSC Q+ C CE P P YSC C
Sbjct: 253 EHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQPGSYSCMC 310
Query: 297 RLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGISCSP 352
G+R A D HRC D D+C + C Q CVN GGFEC+C ++L DG P
Sbjct: 311 ETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGECVEP 365
>ref|NP_000352.1| thrombomodulin [Homo sapiens]
sp|P07204|TRBM_HUMAN THROMBOMODULIN PRECURSOR (FETOMODULIN) (TM) (CD141 ANTIGEN)
gb|AAB59508.1| (M16552) thrombomodulin [Homo sapiens]
gb|AAA61175.1| (J02973) thrombomodulin precursor [Homo sapiens]
emb|CAB51954.1| (AL049651) dJ753D10.2 (thrombomodulin) [Homo sapiens]
gb|AAD49735.1|AF169484_1 (AF169484) thrombomodulin precursor [Saimiri sciureus]
Length = 575
Score = 201 bits (505), Expect = 3e-50
Identities = 135/357 (37%), Positives = 168/357 (46%), Gaps = 33/357 (9%)
Query: 20 PWAAEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGA 76
P AEP+ + C C+AL+P TFL A + C L G L T R+ A + L+
Sbjct: 18 PAPAEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNG 77
Query: 77 --GPASRLLWIGXXX--XXXXXXXXXXXXGFTWTTGDQDTAFTNWAQ-PASGGPCPAQRC 131
G R LWIG GF W TGD +T+++ WA+ +G P C
Sbjct: 78 DGGVGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLC 137
Query: 132 VALEAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAV---YTTPF 183
VA+ A+ E W E C + DG+LC+F F C L E G A AV Y TPF
Sbjct: 138 VAVSAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITYGTPF 197
Query: 184 HLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVG-WSRAGPLCLGTGCSPDNGGC 242
+F+ LP GS AAV A G L+C P G W+R P CS +NGGC
Sbjct: 198 AARGADFQALPVGSSAAV---APLGLQLMCTAPPGAVQGHWAREAP--GAWDCSVENGGC 252
Query: 243 EHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGGPQGYSCHC 296
EH C + G C+C G L ADGRSC Q+ C CE P P YSC C
Sbjct: 253 EHAC-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQPGSYSCMC 310
Query: 297 RLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGISCSP 352
G+R A D HRC D D+C + C Q CVN GGFEC+C ++L DG P
Sbjct: 311 ETGYRLAADQ-HRCEDVDDCILEPSPCPQRCVNTQGGFECHCYPNYDL-VDGECVEP 365
>gb|AAB27209.1| thrombomodulin [human, urine, Peptide, 468 aa]
Length = 468
Score = 197 bits (495), Expect = 5e-49
Identities = 133/354 (37%), Positives = 166/354 (46%), Gaps = 33/354 (9%)
Query: 23 AEPR---AACGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGA--G 77
AEP+ + C C+AL+P TFL A + C L G L T R+ A + L+ G
Sbjct: 3 AEPQPGGSQCVEHDCFALYPGPATFLNASQICDGLRGHLMTVRSSVAADVISLLLNGDGG 62
Query: 78 PASRLLWIGXXX--XXXXXXXXXXXXGFTWTTGDQDTAFTNWAQ-PASGGPCPAQRCVAL 134
R LWIG GF W TGD +T+++ WA+ +G P CVA+
Sbjct: 63 VGRRRLWIGLQLPPGCGDPKRLGPLRGFQWVTGDNNTSYSRWARLDLNGAPLCGPLCVAV 122
Query: 135 EAS-----GEHRWLEGSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAV---YTTPFHLV 186
A+ E W E C + DG+LC+F F C L E G A AV Y TPF
Sbjct: 123 SAAEATVPSEPIWEEQQCEVKADGFLCEFHFPATCRPLAVEPGAAAAAVSITYGTPFAAR 182
Query: 187 STEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVG-WSRAGPLCLGTGCSPDNGGCEHE 245
+F+ LP GS AAV A G L+C P G W+R P CS +NGGCEH
Sbjct: 183 GADFQALPVGSSAAV---APLGLQLMCTAPPGAVQGHWAREAP--GAWDCSVENGGCEHA 237
Query: 246 CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGGPQGYSCHCRLG 299
C + G C+C G L ADGRSC Q+ C CE P P YSC C G
Sbjct: 238 C-NAIPGAPRCQCPAGAALQADGRSCTASATQS-CNDLCEHFCVPNPDQPGSYSCMCETG 295
Query: 300 FRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGISCSP 352
+R A D HRC D D+C + C Q CV GGFEC+C ++L DG P
Sbjct: 296 YRLAADQ-HRCEDVDDCILEPSPCPQRCVXTQGGFECHCYPNYDL-VDGECVEP 347
>ref|NP_034870.1| lymphocyte antigen 68 [Mus musculus]
gb|AAC62649.1| (AF081789) cell surface antigen AA4 [Mus musculus]
gb|AAC63274.1| (AF074856) C1q/MBL/SPA receptor C1qRp [Mus musculus]
gb|AAD47906.1| (AF099939) C1q/MBL/SP-A phagocytic receptor C1qRp [Mus musculus]
Length = 644
Score = 182 bits (456), Expect = 2e-44
Identities = 127/369 (34%), Positives = 173/369 (46%), Gaps = 53/369 (14%)
Query: 16 LGQDPWA---AEPRAA-CGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVD 71
LGQ PWA A+ +A C ++CY + + EA C E GG+LAT ++ EEA+ V
Sbjct: 14 LGQ-PWAGAAADSQAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQ 72
Query: 72 S-----LVGAGPASRLL---WIGXXXXXXXXXXXXX-XXGFTWTTGDQDTAFTNWAQPAS 122
L P + WIG GF+W G +DTA++NW + AS
Sbjct: 73 QALTQLLKTKAPLEAKMGKFWIGLQREKGNCTYHDLPMRGFSWVGGGEDTAYSNWYK-AS 131
Query: 123 GGPCPAQRCVAL--------EASGEHRWLEGSCTL------AVDGYLCQFGFEGACPALQ 168
C +RCV+L S +W E C +++G+LC+F F+G C L
Sbjct: 132 KSSCIFKRCVSLILDLSLTPHPSHLPKWHESPCGTPEAPGNSIEGFLCKFNFKGMCRPLA 191
Query: 169 DEAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGAS---LLCVKQPEGGVGWSR 225
G G YTTPF ++ E +PF SVA V C + LC ++ G W
Sbjct: 192 --LGGPGRVTYTTPFQATTSSLEAVPFASVANVACGDEAKSETHYFLCNEKTPGIFHWGS 249
Query: 226 AGPLCLGT--GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCE 281
+GPLC+ GCS +NGGC+ +C E DG C C GFRL D +C +PC+ PC
Sbjct: 250 SGPLCVSPKFGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPC- 308
Query: 282 QQCEPGG--------PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGF 333
GG + Y+C C G++ H CVD DECQ C Q CVN +G F
Sbjct: 309 ----TGGGMCHSVPLSENYTCRCPSGYQLDSSQVH-CVDIDECQ-DSPCAQDCVNTLGSF 362
Query: 334 ECYCSEGHE 342
C C G++
Sbjct: 363 HCECWVGYQ 371
>gb|AAG01572.1|AF136537_1 (AF136537) C1q/MBL/SPA receptor C1qRp precursor [Rattus norvegicus]
Length = 643
Score = 181 bits (455), Expect = 2e-44
Identities = 119/360 (33%), Positives = 168/360 (46%), Gaps = 49/360 (13%)
Query: 22 AAEPRAA-CGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGA---- 76
AA+ A C ++CY + + EA C E GG+LAT ++ EEA+ V +
Sbjct: 22 AADSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLKT 81
Query: 77 -GPASRLL---WIGXXXXXXXXXXXXX-XXGFTWTTGDQDTAFTNWAQPASGGPCPAQRC 131
P+ + WIG GF+W G +DT ++NW + AS C ++RC
Sbjct: 82 KAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYK-ASKSSCISKRC 140
Query: 132 VAL--------EASGEHRWLEGSCTL------AVDGYLCQFGFEGACPALQDEAGQAGPA 177
V+L S +W E C +++G+LC+F F+G C L G G
Sbjct: 141 VSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLA--LGGPGQL 198
Query: 178 VYTTPFHLVSTEFEWLPFGSVAAVQC---QAGRGASLLCVKQPEGGVGWSRAGPLCLGT- 233
YTTPF ++ + +PF SVA V C + LC + G W +GPLC+
Sbjct: 199 TYTTPFQATTSSLKAVPFASVANVVCGDEAESKTNYYLCKETTAGVFHWGSSGPLCVSPK 258
Query: 234 -GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCEQQCEPGG-- 288
GCS +NGGC+ +C E DG C C GFRL D +C +PC+ PC GG
Sbjct: 259 FGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPC-----TGGGM 313
Query: 289 ------PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 342
+ Y+CHC G++ H CVD DEC+ C Q C+N GGF C C G++
Sbjct: 314 CHSVPLSENYTCHCPRGYQLDSSQVH-CVDIDECE-DSPCDQECINTPGGFHCECWVGYQ 371
>gb|AAF80402.1|AF160978_1 (AF160978) C1qRp [Rattus norvegicus]
Length = 643
Score = 181 bits (455), Expect = 2e-44
Identities = 119/360 (33%), Positives = 168/360 (46%), Gaps = 49/360 (13%)
Query: 22 AAEPRAA-CGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGA---- 76
AA+ A C ++CY + + EA C E GG+LAT ++ EEA+ V +
Sbjct: 22 AADSEAVVCEGTACYTAHWGKLSAAEAQHRCNENGGNLATVKSEEEARHVQEALAQLLKT 81
Query: 77 -GPASRLL---WIGXXXXXXXXXXXXX-XXGFTWTTGDQDTAFTNWAQPASGGPCPAQRC 131
P+ + WIG GF+W G +DT ++NW + AS C ++RC
Sbjct: 82 KAPSETKIGKFWIGLQREKGKCTYHDLPMKGFSWVGGGEDTTYSNWYK-ASKSSCISKRC 140
Query: 132 VAL--------EASGEHRWLEGSCTL------AVDGYLCQFGFEGACPALQDEAGQAGPA 177
V+L S +W E C +++G+LC+F F+G C L G G
Sbjct: 141 VSLILDLSLKPHPSHLPKWHESPCGTPDAPGNSIEGFLCKFNFKGMCSPLA--LGGPGQL 198
Query: 178 VYTTPFHLVSTEFEWLPFGSVAAVQC---QAGRGASLLCVKQPEGGVGWSRAGPLCLGT- 233
YTTPF ++ + +PF SVA V C + LC + G W +GPLC+
Sbjct: 199 TYTTPFQATTSSLKAVPFASVANVVCGDEAESKTNYYLCKETTAGVFHWGSSGPLCVSPK 258
Query: 234 -GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCEQQCEPGG-- 288
GCS +NGGC+ +C E DG C C GFRL D +C +PC+ PC GG
Sbjct: 259 FGCSFNNGGCQQDCFEGGDGSFRCGCRPGFRLLDDLVTCASRNPCSSNPC-----TGGGM 313
Query: 289 ------PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 342
+ Y+CHC G++ H CVD DEC+ C Q C+N GGF C C G++
Sbjct: 314 CHSVPLSENYTCHCPRGYQLDSSQVH-CVDIDECE-DSPCDQECINTPGGFHCECWVGYQ 371
>ref|NP_033404.1| thrombomodulin [Mus musculus]
sp|P15306|TRBM_MOUSE THROMBOMODULIN PRECURSOR (FETOMODULIN) (TM)
pir||A60501 thrombomodulin precursor - mouse
emb|CAA32597.1| (X14432) thrombomodulin [Mus musculus]
Length = 577
Score = 181 bits (455), Expect = 2e-44
Identities = 119/337 (35%), Positives = 153/337 (45%), Gaps = 32/337 (9%)
Query: 29 CGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGXX 88
C C+ALF TFL+A +AC+ L G L T R+ A + L+ WIG
Sbjct: 30 CVEHECFALFQGPATFLDASQACQRLQGHLMTVRSSVAADVISLLLSQSSMDLGPWIGLQ 89
Query: 89 --XXXXXXXXXXXXXGFTWTTGDQDTAFTNWAQP-ASGGPCPAQRCVALE-----ASGEH 140
GF W TGD T+++ WA+P P CV + A GE
Sbjct: 90 LPQGCDDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQTAPLCGPLCVTVSTATEAAPGEP 149
Query: 141 RWLEGSCTLAVDGYLCQFGFEGACPAL----QDEAGQAGPAVYTTPFHLVSTEFEWLPFG 196
W E C G+LC+F F +C L +D + Y TPF + +F+ LP G
Sbjct: 150 AWEEKPCETETQGFLCEFYFTASCRPLTVNTRDPEAAHISSTYNTPFGVSGADFQTLPVG 209
Query: 197 SVAAVQCQAGRGASLLCVKQP---EGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGH 253
S AAV+ G L+C P EG W G CS +NGGCE+ C +
Sbjct: 210 SSAAVE---PLGLELVCRAPPGTSEGHWAWEATG----AWNCSVENGGCEYLCNRSTN-E 261
Query: 254 VSCRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGGPQGYSCHCRLGFRPAEDDP 307
C C L ADGRSC P Q+ C + CE P YSC C G++ A D
Sbjct: 262 PRCLCPRDMDLQADGRSCARPVVQS-CNELCEHFCVSNAEVPGSYSCMCETGYQLAADG- 319
Query: 308 HRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHEL 343
HRC D D+C Q C Q+CVN GGFEC+C +G+EL
Sbjct: 320 HRCEDVDDCKQGPNPCPQLCVNTKGGFECFCYDGYEL 356
>emb|CAC00597.1| (AL118508) dJ737E23.1 (EGF-like domains containing C1q/MBL/SPA
receptor (C1QR)) [Homo sapiens]
Length = 652
Score = 179 bits (449), Expect = 1e-43
Identities = 117/349 (33%), Positives = 163/349 (46%), Gaps = 40/349 (11%)
Query: 29 CGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG------AGPASRL 82
C ++CY + + EA C + GG+LAT ++ EEAQ V ++ A +R+
Sbjct: 31 CVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARM 90
Query: 83 --LWIGXXXXXXXXXXXXX-XXGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEA--- 136
WIG GF+W G +DT ++NW + C ++RCV+L
Sbjct: 91 SKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNS-CISKRCVSLLLDLS 149
Query: 137 -----SGEHRWLEGSCTLA------VDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHL 185
S +W EG C ++G++C+F F+G C L G G YTTPF
Sbjct: 150 QPLLPSRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLA--LGGPGQVTYTTPFQT 207
Query: 186 VSTEFEWLPFGSVAAVQCQAG-----RGASLLCVKQPEGGVGWSRAGPLCLGT--GCSPD 238
S+ E +PF S A V C G + LC ++ W +GPLC+ GC+ +
Sbjct: 208 TSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFN 267
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCEQQCE-PGGPQG--YS 293
NGGC +C E DG C C GFRL D +C +PC+ +PC GP G Y+
Sbjct: 268 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYT 327
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 342
C C G++ + CVD DECQ C Q CVN GGF C C G+E
Sbjct: 328 CRCPQGYQ-LDSSQLDCVDVDECQ-DSPCAQECVNTPGGFRCECWVGYE 374
>ref|NP_036204.1| complement component C1q receptor [Homo sapiens]
gb|AAB53110.1| (U94333) C1qR(p) [Homo sapiens]
Length = 652
Score = 178 bits (448), Expect = 1e-43
Identities = 116/349 (33%), Positives = 162/349 (46%), Gaps = 40/349 (11%)
Query: 29 CGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVG------AGPASRL 82
C ++CY + + EA C + GG+LAT ++ EEAQ V ++ A +R+
Sbjct: 31 CVGTACYTAHSGKLSAAEAQNHCNQNGGNLATVKSKEEAQHVQRVLAQLLRREAALTARM 90
Query: 83 --LWIGXXXXXXXXXXXXX-XXGFTWTTGDQDTAFTNWAQPASGGPCPAQRCVALEASGE 139
WIG GF+W G +DT ++NW + C ++RCV+L
Sbjct: 91 SKFWIGLQREKGKCLDPSLPLKGFSWVGGGEDTPYSNWHKELRNS-CISKRCVSLLLDLS 149
Query: 140 H--------RWLEGSCTLA------VDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHL 185
+W EG C ++G++C+F F+G C L G G YTTPF
Sbjct: 150 QPLLPNRLPKWSEGPCGSPGSPGSNIEGFVCKFSFKGMCRPLA--LGGPGQVTYTTPFQT 207
Query: 186 VSTEFEWLPFGSVAAVQCQAG-----RGASLLCVKQPEGGVGWSRAGPLCLGT--GCSPD 238
S+ E +PF S A V C G + LC ++ W +GPLC+ GC+ +
Sbjct: 208 TSSSLEAVPFASAANVACGEGDKDETQSHYFLCKEKAPDVFDWGSSGPLCVSPKYGCNFN 267
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAPCEQQCE-PGGPQG--YS 293
NGGC +C E DG C C GFRL D +C +PC+ +PC GP G Y+
Sbjct: 268 NGGCHQDCFEGGDGSFLCGCRPGFRLLDDLVTCASRNPCSSSPCRGGATCVLGPHGKNYT 327
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 342
C C G++ + CVD DECQ C Q CVN GGF C C G+E
Sbjct: 328 CRCPQGYQ-LDSSQLDCVDVDECQ-DSPCAQECVNTPGGFRCECWVGYE 374
>gb|AAB80760.1| (AF022743) thrombomodulin [Rattus norvegicus]
Length = 577
Score = 178 bits (447), Expect = 2e-43
Identities = 119/335 (35%), Positives = 151/335 (44%), Gaps = 28/335 (8%)
Query: 29 CGPSSCYALFPRRRTFLEAWRACRELGGDLATPRTPEEAQRVDSLVGAGPASRLLWIGXX 88
C + C+ALF TFL+A +AC+ L G L T R+ A + LV WIG
Sbjct: 30 CVGNECFALFQDPVTFLDASQACQRLQGHLMTVRSSVAADVISLLVSDSSMDSRPWIGLQ 89
Query: 89 --XXXXXXXXXXXXXGFTWTTGDQDTAFTNWAQPASGGP------CPAQRCVALEASGEH 140
GF W TGD T+++ WA+P P C A GE
Sbjct: 90 LPQGCGDPVHLGPLRGFQWVTGDNHTSYSRWARPNDQSPPLCGPLCVTVSTATEAAPGEP 149
Query: 141 RWLEGSCTLAVDGYLCQFGFEGACPAL----QDEAGQAGPAVYTTPFHLVSTEFEWLPFG 196
W E C G+LC+F F C L +D G + Y TP + +F+ LP G
Sbjct: 150 AWEEKPCENETKGFLCEFYFAAFCRPLRVNTRDPEGAHISSTYNTPLGVSGADFQTLPIG 209
Query: 197 SVAAVQCQAGRGASLLCVKQPEGGVG-WSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVS 255
S A V A G L+C P G W+R + CS +NGGCE+ C +G
Sbjct: 210 SSATV---APFGLELVCRALPGTSEGHWTR--EVTGAWNCSVENGGCEYMCNRSANG-PR 263
Query: 256 CRCTEGFRLAADGRSCEDPCAQAPCEQQCE------PGGPQGYSCHCRLGFRPAEDDPHR 309
C C G L ADGRSC P AQ C + C+ P YSC C G++ A D HR
Sbjct: 264 CVCPSGGDLQADGRSCAKPVAQL-CNELCQHFCVNNSDVPGSYSCMCETGYQLAADG-HR 321
Query: 310 CVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHEL 343
C D D+C Q C Q+C N GGFEC C +G+EL
Sbjct: 322 CEDVDDCKQGPNPCPQLCSNTEGGFECRCYDGYEL 356
Score = 35.2 bits (79), Expect = 2.8
Identities = 14/32 (43%), Positives = 18/32 (55%)
Query: 320 GVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
G C+ MC G C C G +L+ADG SC+
Sbjct: 249 GGCEYMCNRSANGPRCVCPSGGDLQADGRSCA 280
>sp|P06579|TRBM_BOVIN THROMBOMODULIN (FETOMODULIN) (TM)
pir||A25918 thrombomodulin - bovine (fragment)
gb|AAA30785.1| (M14657) thrombomodulin [Bos taurus]
Length = 356
Score = 102 bits (252), Expect = 1e-20
Identities = 58/135 (42%), Positives = 69/135 (50%), Gaps = 11/135 (8%)
Query: 223 WSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC----EDPCAQA 278
WSR P C + GGC+HEC G +C C L ADGRSC E PC Q
Sbjct: 11 WSREAPGAWA--CGVERGGCQHECKGSA-GASNCLCPADAALQADGRSCGLPAEHPCHQL 67
Query: 279 PCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYC 337
CE C G Y+C C G++ A D HRC D D+C Q+ C Q CVN GGF+C+C
Sbjct: 68 -CEHFCHLHGLGNYTCICEAGYQLAADQ-HRCEDVDDCAQLPSPCPQRCVNTEGGFQCHC 125
Query: 338 SEGHELEADGISCSP 352
G+EL DG P
Sbjct: 126 DTGYEL-VDGECVDP 139
Score = 66.0 bits (158), Expect = 2e-09
Identities = 43/156 (27%), Positives = 53/156 (33%), Gaps = 41/156 (26%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAPCEQQCEPGGPQGY 292
C+ C CV +G C C G+ L DG + DPC CE QC+P G +
Sbjct: 103 CAQLPSPCPQRCVN-TEGGFQCHCDTGYELV-DGECVDPVDPCFDNNCEYQCQPVGRSEH 160
Query: 293 SCHCRLGFRPAEDDPHRC-----------------------------------VDTDECQ 317
C C GF P PH+C D +EC
Sbjct: 161 KCICAEGFAPVPGAPHKCQMFCNQTSCPADCDPHYPTICRCPEGYIIDEGSTCTDINECD 220
Query: 318 IAGVCQQMCVNYVGGFECYCSEGHELEAD-GISCSP 352
+C C N G +EC C L GI C P
Sbjct: 221 -TNICPGQCHNLPGTYECICGPDSALSGQIGIDCDP 255
>gb|AAB49723.1| (U90121) thrombomdulin [artificial sequence]
Length = 461
Score = 99.1 bits (243), Expect = 2e-19
Identities = 88/348 (25%), Positives = 109/348 (31%), Gaps = 130/348 (37%)
Query: 115 TNWAQPASGGPCPAQRCVALEASGEHRWLEGSCTLAVDGYLCQFGFEGACPA-----LQD 169
T+ + P G C A GE W E C G+LC+F F C +D
Sbjct: 7 TDQSPPLCGPLCVTVSTATEAAPGEPAWEEKPCENETKGFLCEFYFAAFCSRPLRVNTRD 66
Query: 170 EAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQAGRGASLLCVKQPEGGVG-WSRAGP 228
G + Y TP + +F+ LP GS A V A G L+C P G W+R
Sbjct: 67 PEGAHISSTYNTPLGVSGADFQTLPIGSSATV---APFGLELVCRALPGTSEGHWTRE-- 121
Query: 229 LCLGTGCSPDNGGCE----------------------------------------HECVE 248
+ CS +NGGCE H CV
Sbjct: 122 VTGAWNCSVENGGCEYMCNRSANGPRCVCPSGGDLQADGRSCAKPVGQLCNELCQHFCVN 181
Query: 249 --EVDGHVSCRCTEGFRLAADGRSCED--------------------------------- 273
+V G SC C G++LAADG CED
Sbjct: 182 NSDVPGSYSCMCETGYQLAADGHRCEDVDDCKQGPNPCPQLCSNTEGGFECRCYDGYELV 241
Query: 274 ---------PCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHR--------------- 309
PC ++ CE QC+P Y+C C GF P DDP R
Sbjct: 242 DGECVEQLDPCFRSKCEYQCQPVNSTHYNCICAEGFAPKLDDPDRCEMFCNETSCPADCD 301
Query: 310 --------------------CVDTDECQIAGVCQQMCVNYVGGFECYC 337
C D DEC C N G +EC C
Sbjct: 302 PNSPSFCQCPEGFILDEGSICTDIDECSQGECLTNECRNLPGSYECIC 349
Score = 36.0 bits (81), Expect = 1.6
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Query: 320 GVCQQMCVNYVGGFECYCSEGHELEADGISCS-PAGAM 356
G C+ MC G C C G +L+ADG SC+ P G +
Sbjct: 133 GGCEYMCNRSANGPRCVCPSGGDLQADGRSCAKPVGQL 170
>pir||T27283 hypothetical protein Y64G10A.f - Caenorhabditis elegans
Length = 1620
Score = 97.5 bits (239), Expect = 5e-19
Identities = 50/123 (40%), Positives = 65/123 (52%), Gaps = 7/123 (5%)
Query: 233 TGCSPDNGGCEHECVEEVDGHV-SCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPG 287
T CS DNGGCEHEC + +G CRC GF+L+ + RSC+ DPC + C+ C
Sbjct: 200 TSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNN 259
Query: 288 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADG 347
+ C C GF + D CVD DEC C+ C N G + C C EG++L DG
Sbjct: 260 HGRA-QCQCYPGFHLSYDR-RSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDG 317
Query: 348 ISC 350
+C
Sbjct: 318 RTC 320
Score = 84.7 bits (206), Expect = 4e-15
Identities = 51/124 (41%), Positives = 61/124 (49%), Gaps = 8/124 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGPQ 290
C +NG C CV + G V C+C GFRL D ++CED C+ CEQ C
Sbjct: 429 CHENNGDCSQICVN-LAGSVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICS-NQEG 486
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGIS 349
GY C C GF +ED H C D +EC I G C Q+C N G C C G+ L D S
Sbjct: 487 GYMCSCEPGFELSEDG-HSCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKS 545
Query: 350 CSPA 353
C A
Sbjct: 546 CVAA 549
Score = 74.9 bits (181), Expect = 3e-12
Identities = 45/141 (31%), Positives = 59/141 (40%), Gaps = 26/141 (18%)
Query: 234 GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPC-----AQAP--------- 279
GC NGGC+H+C ++ DG C+C G+ LA D + C D A+AP
Sbjct: 326 GCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDNISTVIHARAPRLWDSYETV 385
Query: 280 ---------CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNY 329
C + C C C G+ D C D +EC + G C Q+CVN
Sbjct: 386 TCVTPTDLTCHKLCMHLDSGHVQCFCDDGYELI--DSKFCQDINECHENNGDCSQICVNL 443
Query: 330 VGGFECYCSEGHELEADGISC 350
G EC C G L D +C
Sbjct: 444 AGSVECQCKPGFRLMKDRKTC 464
Score = 72.2 bits (174), Expect = 2e-11
Identities = 44/125 (35%), Positives = 54/125 (43%), Gaps = 10/125 (8%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA--QAPCEQQCEPGGPQ 290
C +NGGCEHECV + G CRC GF L+ DG +C D CA C +C P
Sbjct: 120 CMANNGGCEHECVNTI-GTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSDRCV-NSPG 177
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGG--FECYCSEGHELEADG 347
G+ C C D C C G C+ C N G + C C G +L +
Sbjct: 178 GFRCDCPSDLY-LHADGRTCGKVTSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENK 236
Query: 348 ISCSP 352
SC P
Sbjct: 237 RSCQP 241
Score = 71.4 bits (172), Expect = 3e-11
Identities = 44/123 (35%), Positives = 57/123 (45%), Gaps = 8/123 (6%)
Query: 233 TGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGG 288
T +P + C C+ GHV C C +G+ L D + C+D C + C Q C
Sbjct: 386 TCVTPTDLTCHKLCMHLDSGHVQCFCDDGYELI-DSKFCQDINECHENNGDCSQICV-NL 443
Query: 289 PQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADG 347
C C+ GFR +D C D EC G C+Q+C N GG+ C C G EL DG
Sbjct: 444 AGSVECQCKPGFRLMKDRK-TCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDG 502
Query: 348 ISC 350
SC
Sbjct: 503 HSC 505
Score = 60.9 bits (145), Expect = 5e-08
Identities = 49/138 (35%), Positives = 56/138 (40%), Gaps = 16/138 (11%)
Query: 222 GWSRAGPLCLGTGCSPD---NGGCEHECV--EEVDGHVSCRCTEGFRLAA---DGRSCED 273
G S+ L + CS D NGG CV E D C C GF A D C
Sbjct: 66 GCSKCCLLRVQANCSADLCHNGGT---CVPSEHNDNEQVCECPVGFTGAKCQYDANECM- 121
Query: 274 PCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGG 332
CE +C Y C C GF D + C D DEC ++ G C CVN GG
Sbjct: 122 -ANNGGCEHECV-NTIGTYYCRCWPGFE-LSGDGNTCSDIDECAVSNGGCSDRCVNSPGG 178
Query: 333 FECYCSEGHELEADGISC 350
F C C L ADG +C
Sbjct: 179 FRCDCPSDLYLHADGRTC 196
Score = 46.9 bits (109), Expect = 8e-04
Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 17/96 (17%)
Query: 269 RSCEDPC---AQAPCEQQ-CEPGG---PQGYS-----CHCRLGFRPAEDDPHRCVDTDEC 316
R C C QA C C GG P ++ C C +GF A+ D +EC
Sbjct: 65 RGCSKCCLLRVQANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQ----YDANEC 120
Query: 317 QIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
G C+ CVN +G + C C G EL DG +CS
Sbjct: 121 MANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCS 156
Score = 39.5 bits (90), Expect = 0.14
Identities = 45/166 (27%), Positives = 59/166 (35%), Gaps = 44/166 (26%)
Query: 225 RAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGF------RLAADGR---SCEDPC 275
R GP C C+ +NGG + + G CRC GF ++ +GR C++ C
Sbjct: 1441 RFGPTCEKI-CNCENGGT----CDRLTGQ--CRCLPGFTGMTCNQVCPEGRFGAGCKEKC 1493
Query: 276 AQA--------------------PCEQQCEPGGPQGYSC--HCRLGFRPAEDDPHRCVDT 313
A CEQ C P G G +C C + D C D
Sbjct: 1494 RCANGHCNASSGECKCNLGFTGPSCEQSC-PSGKYGLNCTLDCECYGQARCDPVQGCCDC 1552
Query: 314 DECQIAGVCQQMCVNYVGGF----ECYCSEGHELE-ADGISCSPAG 354
+ CQ C N G+ C C G + ADG PAG
Sbjct: 1553 PPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAG 1598
>emb|CAB57911.1| (AL110498) contains similarity to Pfam domain: PF00008 (EGF-like
domain), Score=380.3, E-value=6.1e-111, N=34~cDNA EST
yk14g6.3 comes from this gene~cDNA EST yk14g6.5 comes
from this gene~cDNA EST yk172f7.5 comes from this
gene~cDNA EST yk145h2.5 comes>
emb|CAB60454.1| (AL117206) contains similarity to Pfam domain: PF00008 (EGF-like
domain), Score=380.3, E-value=6.1e-111, N=34~cDNA EST
yk14g6.3 comes from this gene~cDNA EST yk14g6.5 comes
from this gene~cDNA EST yk172f7.5 comes from this
gene~cDNA EST yk145h2.5 comes>
Length = 1664
Score = 97.5 bits (239), Expect = 5e-19
Identities = 50/123 (40%), Positives = 65/123 (52%), Gaps = 7/123 (5%)
Query: 233 TGCSPDNGGCEHECVEEVDGHV-SCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPG 287
T CS DNGGCEHEC + +G CRC GF+L+ + RSC+ DPC + C+ C
Sbjct: 212 TSCSTDNGGCEHECENDSNGEFYRCRCRVGFKLSENKRSCQPVDPCFDNKGGCQHHCTNN 271
Query: 288 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADG 347
+ C C GF + D CVD DEC C+ C N G + C C EG++L DG
Sbjct: 272 HGRA-QCQCYPGFHLSYDR-RSCVDIDECAKNNGCEHFCENVKGTYRCKCREGYQLGRDG 329
Query: 348 ISC 350
+C
Sbjct: 330 RTC 332
Score = 89.7 bits (219), Expect = 1e-16
Identities = 48/122 (39%), Positives = 61/122 (49%), Gaps = 7/122 (5%)
Query: 234 GCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGP 289
GC NGGC+H+C ++ DG C+C G+ LA D + C D C + C Q C
Sbjct: 338 GCQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQIC-VNLA 396
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGI 348
C C+ GFR + D C D EC G C+Q+C N GG+ C C G EL DG
Sbjct: 397 GSVECQCKPGFRLMK-DRKTCEDISECSSNNGGCEQICSNQEGGYMCSCEPGFELSEDGH 455
Query: 349 SC 350
SC
Sbjct: 456 SC 457
Score = 89.3 bits (218), Expect = 1e-16
Identities = 65/166 (39%), Positives = 76/166 (45%), Gaps = 18/166 (10%)
Query: 203 CQAGRGASLL-CVKQPEGG-VGWSRAG-------PLCLGTG-CSPDNGGCEHECVEEVDG 252
CQ G G C QP+GG V R G LC C +NG C CV + G
Sbjct: 339 CQVGNGGCQHDCYDQPDGGHVCKCRNGYILANDQKLCHDINECHENNGDCSQICVN-LAG 397
Query: 253 HVSCRCTEGFRLAADGRSCED--PCA--QAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPH 308
V C+C GFRL D ++CED C+ CEQ C GY C C GF +ED H
Sbjct: 398 SVECQCKPGFRLMKDRKTCEDISECSSNNGGCEQICS-NQEGGYMCSCEPGFELSEDG-H 455
Query: 309 RCVDTDECQI-AGVCQQMCVNYVGGFECYCSEGHELEADGISCSPA 353
C D +EC I G C Q+C N G C C G+ L D SC A
Sbjct: 456 SCHDMNECLINNGGCAQLCKNRKGSRRCQCFAGYILAHDEKSCVAA 501
Score = 87.0 bits (212), Expect = 7e-16
Identities = 46/118 (38%), Positives = 59/118 (49%), Gaps = 8/118 (6%)
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED-----PCAQAPCEQQCEPGGPQGYS 293
N GCEH C E V G C+C EG++L DGR+CE+ C+ C G+
Sbjct: 301 NNGCEHFC-ENVKGTYRCKCREGYQLGRDGRTCEEMLGGCQVGNGGCQHDCYDQPDGGHV 359
Query: 294 CHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C CR G+ A +D C D +EC + G C Q+CVN G EC C G L D +C
Sbjct: 360 CKCRNGYILA-NDQKLCHDINECHENNGDCSQICVNLAGSVECQCKPGFRLMKDRKTC 416
Score = 63.6 bits (152), Expect = 8e-09
Identities = 44/137 (32%), Positives = 54/137 (39%), Gaps = 22/137 (16%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA--QAPCEQQCEPGGPQ 290
C +NGGCEHECV + G CRC GF L+ DG +C D CA C +C P
Sbjct: 120 CMANNGGCEHECVNTI-GTYYCRCWPGFELSGDGNTCSDIDECAVSNGGCSDRCV-NSPG 177
Query: 291 GYSCHCRLGFRPAEDDPHRCVD-------------TDECQIAGVCQQMCVNYVGG--FEC 335
G+ C C D C T G C+ C N G + C
Sbjct: 178 GFRCDCPSDLY-LHADGRTCGSGFHFENLILIKKVTSCSTDNGGCEHECENDSNGEFYRC 236
Query: 336 YCSEGHELEADGISCSP 352
C G +L + SC P
Sbjct: 237 RCRVGFKLSENKRSCQP 253
Score = 60.9 bits (145), Expect = 5e-08
Identities = 49/138 (35%), Positives = 56/138 (40%), Gaps = 16/138 (11%)
Query: 222 GWSRAGPLCLGTGCSPD---NGGCEHECV--EEVDGHVSCRCTEGFRLAA---DGRSCED 273
G S+ L + CS D NGG CV E D C C GF A D C
Sbjct: 66 GCSKCCLLRVQANCSADLCHNGGT---CVPSEHNDNEQVCECPVGFTGAKCQYDANECM- 121
Query: 274 PCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGG 332
CE +C Y C C GF D + C D DEC ++ G C CVN GG
Sbjct: 122 -ANNGGCEHECV-NTIGTYYCRCWPGFE-LSGDGNTCSDIDECAVSNGGCSDRCVNSPGG 178
Query: 333 FECYCSEGHELEADGISC 350
F C C L ADG +C
Sbjct: 179 FRCDCPSDLYLHADGRTC 196
Score = 46.9 bits (109), Expect = 8e-04
Identities = 33/96 (34%), Positives = 42/96 (43%), Gaps = 17/96 (17%)
Query: 269 RSCEDPC---AQAPCEQQ-CEPGG---PQGYS-----CHCRLGFRPAEDDPHRCVDTDEC 316
R C C QA C C GG P ++ C C +GF A+ D +EC
Sbjct: 65 RGCSKCCLLRVQANCSADLCHNGGTCVPSEHNDNEQVCECPVGFTGAKCQ----YDANEC 120
Query: 317 QIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
G C+ CVN +G + C C G EL DG +CS
Sbjct: 121 MANNGGCEHECVNTIGTYYCRCWPGFELSGDGNTCS 156
Score = 39.5 bits (90), Expect = 0.14
Identities = 45/166 (27%), Positives = 59/166 (35%), Gaps = 44/166 (26%)
Query: 225 RAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGF------RLAADGR---SCEDPC 275
R GP C C+ +NGG + + G CRC GF ++ +GR C++ C
Sbjct: 1377 RFGPTCEKI-CNCENGGT----CDRLTGQ--CRCLPGFTGMTCNQVCPEGRFGAGCKEKC 1429
Query: 276 AQA--------------------PCEQQCEPGGPQGYSC--HCRLGFRPAEDDPHRCVDT 313
A CEQ C P G G +C C + D C D
Sbjct: 1430 RCANGHCNASSGECKCNLGFTGPSCEQSC-PSGKYGLNCTLDCECYGQARCDPVQGCCDC 1488
Query: 314 DECQIAGVCQQMCVNYVGGF----ECYCSEGHELE-ADGISCSPAG 354
+ CQ C N G+ C C G + ADG PAG
Sbjct: 1489 PPGRYGSRCQFSCPNGFYGWYCSQSCSCQNGAHCDGADGRCLCPAG 1534
Score = 38.3 bits (87), Expect = 0.32
Identities = 42/153 (27%), Positives = 58/153 (37%), Gaps = 31/153 (20%)
Query: 225 RAGPLCLGTGCSPDNGG--CEHEC-------VEEVDGHVSCRCTEGFRLAADGRSCEDPC 275
+ GPLC C+P+ G C H C +E DG SC CT GF A C
Sbjct: 838 KTGPLC-DQSCAPNTYGPNCAHTCSCVNGAKCDESDG--SCHCTPGFYGATCSEVCPTGR 894
Query: 276 AQAPCEQ--QCEPGG---PQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYV 330
C Q +C+ G SC C G+ +C D+ G + C
Sbjct: 895 FGIDCMQLCKCQNGAICDTSNGSCECAPGW-----SGKKC---DKACAPGTFGKDCSK-- 944
Query: 331 GGFECYCSEG-HELEADGISCSPAGAMGAQASQ 362
+C C++G H +DG P G G + +
Sbjct: 945 ---KCDCADGMHCDPSDGECICPPGKKGHKCDE 974
Score = 37.1 bits (84), Expect = 0.72
Identities = 45/163 (27%), Positives = 57/163 (34%), Gaps = 32/163 (19%)
Query: 203 CQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGF 262
C GR S P G GW CS NG C + DG C C GF
Sbjct: 1488 CPPGRYGSRCQFSCPNGFYGWY------CSQSCSCQNGA---HC-DGADGR--CLCPAGF 1535
Query: 263 RLAADGRSCEDPCAQAPCEQQCEPG--GPQGYSCHCRLGFRPAEDDPHRCV--------- 311
++ + D CEQ+C G GP S C G + +C+
Sbjct: 1536 QVKLANKKKNDLELGDKCEQKCSEGSFGP-ACSQQCNCGKYKCDATDGKCICPVGRHGPL 1594
Query: 312 DTDECQIAGVCQQMCVNYVGGFECYCSEGHELEA--DGISCSP 352
+EC+ G Q C N +C C G +A SCSP
Sbjct: 1595 CEEECR-PGRYGQSCQN-----KCQCFNGATCDARTGQCSCSP 1631
>pir||S78040 fibulin, splice form C precursor - mouse
Length = 685
Score = 94.4 bits (231), Expect = 4e-18
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C +PC Q+C Y C+CR G
Sbjct: 413 CGHKC-ENTPGSFHCSCSAGFRLSVDGRSCEDVNECLNSPCSQEC-ANVYGSYQCYCRRG 470
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 471 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 525
Score = 62.5 bits (149), Expect = 2e-08
Identities = 42/134 (31%), Positives = 54/134 (39%), Gaps = 15/134 (11%)
Query: 224 SRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQ 283
S + P +G C G + C + V C G+ L +G C D AP +
Sbjct: 316 SISAPCPVGQTCINTEGS--YTCQKNVPN-----CGRGYHLNEEGTRCVDVDECAPPAEP 368
Query: 284 CEPG-----GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECY 336
C G P + C C+ GF + CVD +ECQ +C C N G F C
Sbjct: 369 CGKGHHCLNSPGSFRCECKAGFY-FDGISRTCVDINECQRYPGRLCGHKCENTPGSFHCS 427
Query: 337 CSEGHELEADGISC 350
CS G L DG SC
Sbjct: 428 CSAGFRLSVDGRSC 441
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 186 GPCKQQCRDTGD-EVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRC 244
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--CQQ--MCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ G+ C +C N +G F C C G
Sbjct: 245 QRDSSCGTGYELTED--NNCKDIDECE-TGIHNCPPDFICQNTLGSFRCRPKLQCKSGFI 301
Query: 343 LEADG 347
+A G
Sbjct: 302 QDALG 306
Score = 39.5 bits (90), Expect = 0.14
Identities = 17/49 (34%), Positives = 26/49 (52%)
Query: 302 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
P E+D D C+ G C+Q C + C C G++L++DG+SC
Sbjct: 168 PDEEDQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSC 216
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 487 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 527
>pir||S34968 fibulin, splice form D precursor - mouse
Length = 705
Score = 94.4 bits (231), Expect = 4e-18
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C +PC Q+C Y C+CR G
Sbjct: 413 CGHKC-ENTPGSFHCSCSAGFRLSVDGRSCEDVNECLNSPCSQEC-ANVYGSYQCYCRRG 470
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 471 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 525
Score = 62.5 bits (149), Expect = 2e-08
Identities = 42/134 (31%), Positives = 54/134 (39%), Gaps = 15/134 (11%)
Query: 224 SRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQ 283
S + P +G C G + C + V C G+ L +G C D AP +
Sbjct: 316 SISAPCPVGQTCINTEGS--YTCQKNVPN-----CGRGYHLNEEGTRCVDVDECAPPAEP 368
Query: 284 CEPG-----GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECY 336
C G P + C C+ GF + CVD +ECQ +C C N G F C
Sbjct: 369 CGKGHHCLNSPGSFRCECKAGFY-FDGISRTCVDINECQRYPGRLCGHKCENTPGSFHCS 427
Query: 337 CSEGHELEADGISC 350
CS G L DG SC
Sbjct: 428 CSAGFRLSVDGRSC 441
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 186 GPCKQQCRDTGD-EVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRC 244
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--CQQ--MCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ G+ C +C N +G F C C G
Sbjct: 245 QRDSSCGTGYELTED--NNCKDIDECE-TGIHNCPPDFICQNTLGSFRCRPKLQCKSGFI 301
Query: 343 LEADG 347
+A G
Sbjct: 302 QDALG 306
Score = 39.5 bits (90), Expect = 0.14
Identities = 17/49 (34%), Positives = 26/49 (52%)
Query: 302 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
P E+D D C+ G C+Q C + C C G++L++DG+SC
Sbjct: 168 PDEEDQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSC 216
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 487 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 527
>ref|NP_034310.1| fibulin 1; BM-90/fibulin extracellular matrix glyroprotein [Mus
musculus]
sp|Q08879|FBL1_MOUSE FIBULIN-1 PRECURSOR (BASEMENT-MEMBRANE PROTEIN 90) (BM-90)
pir||S36441 fibulin - mouse
emb|CAA50207.1| (X70854) BM-90/fibulin [Mus musculus]
Length = 705
Score = 94.4 bits (231), Expect = 4e-18
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C +PC Q+C Y C+CR G
Sbjct: 413 CGHKC-ENTPGSFHCSCSAGFRLSVDGRSCEDVNECLNSPCSQEC-ANVYGSYQCYCRRG 470
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 471 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 525
Score = 62.5 bits (149), Expect = 2e-08
Identities = 42/134 (31%), Positives = 54/134 (39%), Gaps = 15/134 (11%)
Query: 224 SRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQ 283
S + P +G C G + C + V C G+ L +G C D AP +
Sbjct: 316 SISAPCPVGQTCINTEGS--YTCQKNVPN-----CGRGYHLNEEGTRCVDVDECAPPAEP 368
Query: 284 CEPG-----GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECY 336
C G P + C C+ GF + CVD +ECQ +C C N G F C
Sbjct: 369 CGKGHHCLNSPGSFRCECKAGFY-FDGISRTCVDINECQRYPGRLCGHKCENTPGSFHCS 427
Query: 337 CSEGHELEADGISC 350
CS G L DG SC
Sbjct: 428 CSAGFRLSVDGRSC 441
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 52/125 (41%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 186 GPCKQQCRDTGD-EVICSCFVGYQLQSDGVSCEDINECITGSHNCRLGESCINTVGSFRC 244
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--CQQ--MCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ G+ C +C N +G F C C G
Sbjct: 245 QRDSSCGTGYELTED--NNCKDIDECE-TGIHNCPPDFICQNTLGSFRCRPKLQCKSGFI 301
Query: 343 LEADG 347
+A G
Sbjct: 302 QDALG 306
Score = 39.5 bits (90), Expect = 0.14
Identities = 17/49 (34%), Positives = 26/49 (52%)
Query: 302 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
P E+D D C+ G C+Q C + C C G++L++DG+SC
Sbjct: 168 PDEEDQEDPYLNDRCRGGGPCKQQCRDTGDEVICSCFVGYQLQSDGVSC 216
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 487 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 527
>ref|XP_001220.1| fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|XP_001221.1| fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|XP_001224.1| fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|XP_001222.1| fibulin 1 [Homo sapiens]
Length = 717
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>gb|AAG17241.1|AF217999_1 (AF217999) unknown [Homo sapiens]
Length = 495
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 281 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 338
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 339 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 393
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 193 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 251
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 252 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 309
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 54 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 112
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 113 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 169
Query: 343 LEADG 347
+A G
Sbjct: 170 QDALG 174
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 41 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 84
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 355 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 395
>ref|NP_006477.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P37888|FBLD_HUMAN FIBULIN-1, ISOFORM D PRECURSOR
gb|AAB17099.1| (U01244) fibulin-1D [Homo sapiens]
Length = 703
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|NP_001987.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P23144|FBLC_HUMAN FIBULIN-1, ISOFORM C PRECURSOR
pir||C36346 fibulin 1 precursor, splice form C - human
emb|CAA37772.1| (X53743) fibulin-1 C [Homo sapiens]
prf||1704259B fibulin C [Homo sapiens]
Length = 683
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|NP_006476.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P23143|FBLB_HUMAN FIBULIN-1, ISOFORM B PRECURSOR
pir||B36346 fibulin 1 precursor, splice form B - human
emb|CAA37771.1| (X53742) fibulin-1 B [Homo sapiens]
prf||1704259A fibulin B [Homo sapiens]
Length = 601
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>ref|NP_006478.1| fibulin 1 isoform A precursor [Homo sapiens]
sp|P23142|FBLA_HUMAN FIBULIN-1, ISOFORM A PRECURSOR
emb|CAA37770.1| (X53741) fibulin-1 A [Homo sapiens]
Length = 566
Score = 93.2 bits (228), Expect = 9e-18
Identities = 46/115 (40%), Positives = 64/115 (55%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCED C+ +PC Q+C Y C+CR G
Sbjct: 411 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEDINECSSSPCSQEC-ANVYGSYQCYCRRG 468
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 469 YQLSDVDGVTCEDIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 523
Score = 62.5 bits (149), Expect = 2e-08
Identities = 37/119 (31%), Positives = 52/119 (43%), Gaps = 14/119 (11%)
Query: 244 HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYS 293
H C+ +G +C+ C G+ L +G C D AP + C G P +
Sbjct: 323 HTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVDVDECAPPAEPCGKGHRCVNSPGSFR 381
Query: 294 CHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C C+ G+ + CVD +ECQ +C C N +G + C CS G L DG SC
Sbjct: 382 CECKTGYY-FDGISRMCVDVNECQRYPGRLCGHKCENTLGSYLCSCSVGFRLSVDGRSC 439
Score = 45.7 bits (106), Expect = 0.002
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCED C G + C
Sbjct: 184 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEDVNECITGSHSCRLGESCINTVGSFRC 242
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C D DEC+ +G+ C +C N +G F C C G
Sbjct: 243 QRDSSCGTGYELTED--NSCKDIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 299
Query: 343 LEADG 347
+A G
Sbjct: 300 QDALG 304
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 171 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 214
Score = 35.2 bits (79), Expect = 2.8
Identities = 16/42 (38%), Positives = 25/42 (59%), Gaps = 4/42 (9%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCED 273
C+ GG C + C+ + G C C + G+RLA +GR+C+D
Sbjct: 485 CALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQD 525
>emb|CAB46380.1| (AL021578) dJ453C12.3 (matrilin-4) [Homo sapiens]
Length = 622
Score = 92.8 bits (227), Expect = 1e-17
Identities = 50/127 (39%), Positives = 64/127 (50%), Gaps = 8/127 (6%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQC 284
LC C+ GC+H+CV C C G++LAAD +SC D CA+ CE C
Sbjct: 213 LCGKDQCAEGGHGCQHQCVNAW-AMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHC 271
Query: 285 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHEL 343
P Y CHC++GF + D C D C CQ CV+ GG C+C EGH+L
Sbjct: 272 V-NSPGSYFCHCQVGF-VLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDL 329
Query: 344 EADGISC 350
+ DG SC
Sbjct: 330 QPDGRSC 336
Score = 78.4 bits (190), Expect = 3e-13
Identities = 47/124 (37%), Positives = 60/124 (47%), Gaps = 12/124 (9%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQC--EPGG 288
C+ GCEH CV G C C GF L D RSC D C+ C+ +C PGG
Sbjct: 260 CAEGTHGCEHHCVNS-PGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGG 318
Query: 289 PQGYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADG 347
P+ CHCR G + D C D C + C+ CV+ + C C EG +L+ADG
Sbjct: 319 PR---CHCREG-HDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADG 374
Query: 348 ISCS 351
SC+
Sbjct: 375 KSCN 378
>pir||T13954 MEGF6 protein - rat
dbj|BAA32462.1| (AB011532) MEGF6 [Rattus norvegicus]
Length = 1574
Score = 92.4 bits (226), Expect = 2e-17
Identities = 46/120 (38%), Positives = 58/120 (48%), Gaps = 5/120 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGY 292
C NGGC H C G + C C G+ L D ++C D CA +PC QQ P GY
Sbjct: 338 CEAGNGGCSHGCSHTSTGPL-CTCPRGYELDEDQKTCIDIDDCANSPCCQQACANTPGGY 396
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
C C G+R D C D DEC G C+ C N G F+C+C G+ L+ D C+
Sbjct: 397 ECSCFAGYR-LNTDGCGCEDVDECASGHGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCT 455
Score = 84.3 bits (205), Expect = 5e-15
Identities = 52/147 (35%), Positives = 70/147 (47%), Gaps = 10/147 (6%)
Query: 210 SLLCVKQPEGGVGWSRAGPLCLG-TGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADG 268
S LC +P G G CL + C+ NGGC+H+CV+ C+C ++L DG
Sbjct: 185 SYLCECKP--GFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDG 242
Query: 269 RSC--EDPCAQ--APCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQ 323
R C PCA+ C C+ + C C G++ A D C D DEC + C
Sbjct: 243 RRCVRRSPCAEGNGGCMHICQELRGLAH-CGCHPGYQLAA-DRKTCEDVDECALGLAQCA 300
Query: 324 QMCVNYVGGFECYCSEGHELEADGISC 350
C+N G F+C C G+EL ADG C
Sbjct: 301 HGCLNTQGSFKCVCHAGYELGADGRQC 327
Score = 78.4 bits (190), Expect = 3e-13
Identities = 49/165 (29%), Positives = 64/165 (38%), Gaps = 51/165 (30%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED---------PCAQAPCEQQ-- 283
C+ NGGC H C +E+ G C C G++LAAD ++CED CA Q
Sbjct: 251 CAEGNGGCMHIC-QELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCAHGCLNTQGS 309
Query: 284 ----------------------------CEPGG----------PQGYSCHCRLGFRPAED 305
CE G G C C G+ ++
Sbjct: 310 FKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYE-LDE 368
Query: 306 DPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
D C+D D+C + CQQ C N GG+EC C G+ L DG C
Sbjct: 369 DQKTCIDIDDCANSPCCQQACANTPGGYECSCFAGYRLNTDGCGC 413
Score = 55.4 bits (131), Expect = 2e-06
Identities = 39/122 (31%), Positives = 48/122 (38%), Gaps = 27/122 (22%)
Query: 230 CLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP 289
C G P GC + +VD C G CE PC C G
Sbjct: 108 CPGWSQKPGQEGC----LSDVD---ECASANG--------GCEGPC--------CNTVG- 143
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGI 348
G+ C C G++ + D C D DEC+ G CQ CVN G + C C G L DG
Sbjct: 144 -GFYCRCPPGYQ-LQGDGKTCQDVDECRAHNGGCQHRCVNTPGSYLCECKPGFRLHTDGR 201
Query: 349 SC 350
+C
Sbjct: 202 TC 203
Score = 41.8 bits (96), Expect = 0.028
Identities = 47/149 (31%), Positives = 52/149 (34%), Gaps = 33/149 (22%)
Query: 222 GWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCE 281
GW G C P N C H E CRC GF G SCE C
Sbjct: 1169 GWF--GEACAQRCLCPTNASCHHVTGE-------CRCPPGF----TGLSCEQACQPGTFG 1215
Query: 282 QQCEPGGPQGYSCHCRLGFRPAED---DPHRCVDTDECQIAGV-CQQMCVN--YVGGFE- 334
+ CE + C C P E DP V T G C Q C + Y G E
Sbjct: 1216 KDCE------HLCQC-----PGETWACDPASGVCTCAAGYHGTGCLQRCPSGRYGPGCEH 1264
Query: 335 -CYCSEGHELE-ADGISCSPAGAMGAQAS 361
C C G + A G PAG +GA S
Sbjct: 1265 ICKCLNGGTCDPATGACYCPAGFLGADCS 1293
Score = 38.3 bits (87), Expect = 0.32
Identities = 50/196 (25%), Positives = 67/196 (33%), Gaps = 46/196 (23%)
Query: 196 GSVAAVQCQAG---RGASLLCVKQPEGG----VGWSRAGPLCLGTGCSP--DNGGCEHEC 246
GS C AG G + C +G G P G C D+G +C
Sbjct: 814 GSRCQDTCSAGWYGTGCQIRCACANDGHCDPTTGRCSCAPGWTGLSCQRACDSGHWGPDC 873
Query: 247 VEEVD---GHVSCRCTEGFRLAA---DGRSCEDPCAQA----PCEQ--QCEPGGPQGY-- 292
+ + GH +C G L +G CE C Q CEQ +CE G +
Sbjct: 874 IHPCNCSAGHGNCDAVSGLCLCEAGYEGPRCEQSCRQGYYGPSCEQKCRCEHGAACDHVS 933
Query: 293 -SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFE----CYCSEGHELEADG 347
+C C G+R C+ C G + C CS G +A
Sbjct: 934 GACTCPAGWR-----------------GSFCEHACPAGFFGLDCDSACNCSAGAPCDAVT 976
Query: 348 ISC-SPAGAMGAQASQ 362
SC PAG G + +Q
Sbjct: 977 GSCICPAGRWGPRCAQ 992
Score = 36.7 bits (83), Expect = 0.94
Identities = 43/157 (27%), Positives = 54/157 (34%), Gaps = 44/157 (28%)
Query: 145 GSCTLAVDGYLCQFGFEGACPALQDEAGQAGPAVYTTPFHLVSTEFEWLPFGSVAAVQCQ 204
G+C A C GF GA +L G+ GP+ A C
Sbjct: 1272 GTCDPATGACYCPAGFLGADCSLACPQGRFGPS---------------------CAHVCA 1310
Query: 205 AGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGG--CEHECVEEVDG---HVSCRCT 259
+GA+ P G C+ CSP G CEH C ++ G + C C
Sbjct: 1311 CRQGAAC----DPVSGA--------CI---CSPGKTGVRCEHGCPQDRFGKGCELKCACR 1355
Query: 260 EGFRLAADGRSCEDPCA-QAP-CEQQCEPGGPQGYSC 294
G A SC P P CE C P G G +C
Sbjct: 1356 NGGLCHATNGSCSCPLGWMGPHCEHAC-PAGRYGAAC 1391
Score = 34.4 bits (77), Expect = 4.8
Identities = 44/144 (30%), Positives = 51/144 (34%), Gaps = 21/144 (14%)
Query: 228 PLCLGTGCSPDNGGCEHECVEEV---DGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQ- 283
P G GCS D CE DG SC C GF+ CE C +
Sbjct: 647 PWAFGPGCSEDCL-CEQSHTRSCNPKDG--SCSCKAGFQGERCQAECESGFFGPGCRHRC 703
Query: 284 -CEPG---GPQGYSC--HCRLGFRPAEDDPHRC-VDTDECQIAGVCQQM---CVNYVGGF 333
C+PG P C C G++ ED C V T +G C + C G
Sbjct: 704 TCQPGVACDPVSGECRTQCPPGYQ-GEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTG-- 760
Query: 334 ECYCSEGHELEADGISCSPAGAMG 357
EC C G E G C P G G
Sbjct: 761 ECLCPPGKTGEDCGADC-PEGRWG 783
>sp|O73775|FBL1_CHICK FIBULIN-1 PRECURSOR
gb|AAC05388.1| (AF051400) fibulin-1, isoform C precursor [Gallus gallus]
Length = 684
Score = 92.4 bits (226), Expect = 2e-17
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C CT GF+L++DGRSCED C +PC Q+C Y C+CR G
Sbjct: 412 CAHKC-ENTPGSYYCTCTMGFKLSSDGRSCEDLNECESSPCSQEC-ANVYGSYQCYCRRG 469
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
F+ ++ D C D DEC + +C C+N G F+C C S G+ L + +C
Sbjct: 470 FQLSDIDGISCEDIDECALPTGGHICSFRCINIPGSFQCTCPSTGYRLAPNARNC 524
Score = 61.7 bits (147), Expect = 3e-08
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 13/112 (11%)
Query: 251 DGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYSCHCRLGF 300
DG +C+ C G+ L DG C D + +Q C G GP Y C C+ G+
Sbjct: 330 DGSYTCQRISPSCGRGYHLNEDGTRCVDVDECSSSDQPCGEGHVCINGPGNYRCECKSGY 389
Query: 301 RPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ C+D +EC+ +C C N G + C C+ G +L +DG SC
Sbjct: 390 S-FDVISRTCIDINECRRYPGRLCAHKCENTPGSYYCTCTMGFKLSSDGRSC 440
Score = 40.2 bits (92), Expect = 0.083
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 26/122 (21%)
Query: 231 LGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ 290
L GC G C +C + +V C C G++L DG +CED +C G
Sbjct: 177 LHDGCR-GGGPCSQQCRDTGSSYV-CSCFVGYQLQPDGVNCED-------INECITGTHS 227
Query: 291 ---GYSCHCRLG-FRPAED----------DPHRCVDTDECQI-AGVCQQ--MCVNYVGGF 333
G +C LG FR D D RC D DEC+ C +C N G F
Sbjct: 228 CGIGQTCVNTLGSFRCQRDTSCGTGYELTDDSRCKDIDECETGTHNCPPDFICQNTPGSF 287
Query: 334 EC 335
C
Sbjct: 288 RC 289
Score = 38.7 bits (88), Expect = 0.24
Identities = 40/200 (20%), Positives = 67/200 (33%), Gaps = 64/200 (32%)
Query: 207 RGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHE----CVEEVDGHVSCRCTEGF 262
RG L + + GV W+ +C ++ C C +++ H C++G
Sbjct: 24 RGQDLSMEECCDKGVEWANKNRICTSLPLISESRECSMTQVQCCRSKLEEHY---CSDGI 80
Query: 263 RLAADGRSCEDPCAQ-APCE---------------------QQCEPGGPQGYSCHCRLGF 300
A+ C+ + + CE Q CEP GY C + F
Sbjct: 81 EFASVHEECDSHNGENSTCEAEYFKKCCYCCLLGKTAQVQGQSCEPNLKIGYQCG--IVF 138
Query: 301 RPA------------------------------EDDPHRCVDTDECQIAGVCQQMCVNYV 330
R ++DP+ D C+ G C Q C +
Sbjct: 139 RACCVKGQEGTDVSISDDAPKKEQVEISKEELDQEDPYL---HDGCRGGGPCSQQCRDTG 195
Query: 331 GGFECYCSEGHELEADGISC 350
+ C C G++L+ DG++C
Sbjct: 196 SSYVCSCFVGYQLQPDGVNC 215
>gb|AAC05387.1| (AF051399) fibulin-1, isoform D precursor [Gallus gallus]
Length = 704
Score = 92.4 bits (226), Expect = 2e-17
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C CT GF+L++DGRSCED C +PC Q+C Y C+CR G
Sbjct: 412 CAHKC-ENTPGSYYCTCTMGFKLSSDGRSCEDLNECESSPCSQEC-ANVYGSYQCYCRRG 469
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
F+ ++ D C D DEC + +C C+N G F+C C S G+ L + +C
Sbjct: 470 FQLSDIDGISCEDIDECALPTGGHICSFRCINIPGSFQCTCPSTGYRLAPNARNC 524
Score = 61.7 bits (147), Expect = 3e-08
Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 13/112 (11%)
Query: 251 DGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCEQQCEPG-----GPQGYSCHCRLGF 300
DG +C+ C G+ L DG C D + +Q C G GP Y C C+ G+
Sbjct: 330 DGSYTCQRISPSCGRGYHLNEDGTRCVDVDECSSSDQPCGEGHVCINGPGNYRCECKSGY 389
Query: 301 RPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ C+D +EC+ +C C N G + C C+ G +L +DG SC
Sbjct: 390 S-FDVISRTCIDINECRRYPGRLCAHKCENTPGSYYCTCTMGFKLSSDGRSC 440
Score = 40.2 bits (92), Expect = 0.083
Identities = 38/122 (31%), Positives = 48/122 (39%), Gaps = 26/122 (21%)
Query: 231 LGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQ 290
L GC G C +C + +V C C G++L DG +CED +C G
Sbjct: 177 LHDGCR-GGGPCSQQCRDTGSSYV-CSCFVGYQLQPDGVNCED-------INECITGTHS 227
Query: 291 ---GYSCHCRLG-FRPAED----------DPHRCVDTDECQI-AGVCQQ--MCVNYVGGF 333
G +C LG FR D D RC D DEC+ C +C N G F
Sbjct: 228 CGIGQTCVNTLGSFRCQRDTSCGTGYELTDDSRCKDIDECETGTHNCPPDFICQNTPGSF 287
Query: 334 EC 335
C
Sbjct: 288 RC 289
Score = 38.7 bits (88), Expect = 0.24
Identities = 40/200 (20%), Positives = 67/200 (33%), Gaps = 64/200 (32%)
Query: 207 RGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEHE----CVEEVDGHVSCRCTEGF 262
RG L + + GV W+ +C ++ C C +++ H C++G
Sbjct: 24 RGQDLSMEECCDKGVEWANKNRICTSLPLISESRECSMTQVQCCRSKLEEHY---CSDGI 80
Query: 263 RLAADGRSCEDPCAQ-APCE---------------------QQCEPGGPQGYSCHCRLGF 300
A+ C+ + + CE Q CEP GY C + F
Sbjct: 81 EFASVHEECDSHNGENSTCEAEYFKKCCYCCLLGKTAQVQGQSCEPNLKIGYQCG--IVF 138
Query: 301 RPA------------------------------EDDPHRCVDTDECQIAGVCQQMCVNYV 330
R ++DP+ D C+ G C Q C +
Sbjct: 139 RACCVKGQEGTDVSISDDAPKKEQVEISKEELDQEDPYL---HDGCRGGGPCSQQCRDTG 195
Query: 331 GGFECYCSEGHELEADGISC 350
+ C C G++L+ DG++C
Sbjct: 196 SSYVCSCFVGYQLQPDGVNC 215
>gb|AAG25939.1|AF276425_1 (AF276425) EGF-related protein SCUBE1 [Mus musculus]
Length = 961
Score = 91.3 bits (223), Expect = 4e-17
Identities = 53/153 (34%), Positives = 74/153 (47%), Gaps = 13/153 (8%)
Query: 208 GASLLCVKQPEGGVGWSRAGPLCLGTG-------CSPDNGGCEHECVEEVDGHVSCRCTE 260
G + +C + P+GGV L C+ NGGC+H C E+ D C C +
Sbjct: 172 GCAHICRETPKGGVACDCRPGFDLAQNQKDCTLTCNYGNGGCQHSC-EDTDTGPMCGCHQ 230
Query: 261 GFRLAADGRSCEDPCA--QAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQI 318
+ L ADGR+C + CA C++ C+ G C C +GF + D C D +EC +
Sbjct: 231 KYALHADGRTCIETCAVNNGGCDRTCKDTAT-GVRCSCPVGFT-LQPDGKTCKDINECLM 288
Query: 319 A-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
G C C N VG FEC C +GH+L D +C
Sbjct: 289 NNGGCDHFCRNTVGSFECGCQKGHKLLTDERTC 321
Score = 78.8 bits (191), Expect = 2e-13
Identities = 41/121 (33%), Positives = 58/121 (47%), Gaps = 8/121 (6%)
Query: 227 GPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQ 282
G C+ T C+ +NGGC+ C + G V C C GF L DG++C+D C C+
Sbjct: 238 GRTCIET-CAVNNGGCDRTCKDTATG-VRCSCPVGFTLQPDGKTCKDINECLMNNGGCDH 295
Query: 283 QCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHE 342
C + C C+ G + D+ C D DEC C +C+N G F+C C G+
Sbjct: 296 FCR-NTVGSFECGCQKGHKLLTDE-RTCQDIDECSFERTCDHICINSPGSFQCLCRRGYT 353
Query: 343 L 343
L
Sbjct: 354 L 354
Score = 75.7 bits (183), Expect = 2e-12
Identities = 43/120 (35%), Positives = 58/120 (47%), Gaps = 8/120 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 291
C +NGGC+H C V G C C +G +L D R+C+D C+ + C+ C P
Sbjct: 286 CLMNNGGCDHFCRNTV-GSFECGCQKGHKLLTDERTCQDIDECSFERTCDHICI-NSPGS 343
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ C CR G+ C D DEC + G C+Q CVN G +EC C G L + C
Sbjct: 344 FQCLCRRGYTLYGTT--HCGDVDECSMNNGSCEQGCVNTRGSYECVCPPGRRLHWNQKDC 401
Score = 70.2 bits (169), Expect = 8e-11
Identities = 44/126 (34%), Positives = 56/126 (43%), Gaps = 16/126 (12%)
Query: 235 CSPDNGGCEHECV-EEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGG----- 288
CS C + + + C C G++ +GR CED CE GG
Sbjct: 37 CSEGTDDCHIDAICQNTPKSYKCLCKPGYK--GEGRQCEDI---DECENDYYNGGCVHDC 91
Query: 289 ---PQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELE 344
P Y C C GF A D H C+D DECQ G CQQ+CVN +G +EC C G L
Sbjct: 92 INIPGNYRCTCFDGFMLAHDG-HNCLDVDECQDNNGGCQQICVNAMGSYECQCHSGFFLS 150
Query: 345 ADGISC 350
+ +C
Sbjct: 151 DNQHTC 156
Score = 56.2 bits (133), Expect = 1e-06
Identities = 38/125 (30%), Positives = 53/125 (42%), Gaps = 13/125 (10%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--------PCEQQCEP 286
C +NGGC+ CV + G C+C GF L+ + +C + C C
Sbjct: 121 CQDNNGGCQQICVNAM-GSYECQCHSGFFLSDNQHTCIHRSNEGMNCMNKDHGCAHICRE 179
Query: 287 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 345
G +C CR GF A++ C T C G CQ C + G C C + + L A
Sbjct: 180 TPKGGVACDCRPGFDLAQNQKD-CTLT--CNYGNGGCQHSCEDTDTGPMCGCHQKYALHA 236
Query: 346 DGISC 350
DG +C
Sbjct: 237 DGRTC 241
>gb|AAD34456.1| (AF135253) fibulin-2 [Mus musculus]
Length = 1221
Score = 91.3 bits (223), Expect = 4e-17
Identities = 51/114 (44%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 950 CQHTC-ENTPGSYRCSCAAGFLLAADGKHCEDVNECETRRCSQECA-NIYGSYQCYCRQG 1007
Query: 300 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 350
++ AED H C D DEC Q AG+ C CVN G ++C C E G+ + A+G SC
Sbjct: 1008 YQLAEDG-HTCTDIDECAQGAGILCTFRCVNVPGSYQCACPEQGYTMMANGRSC 1060
Score = 80.4 bits (195), Expect = 7e-14
Identities = 50/145 (34%), Positives = 65/145 (44%), Gaps = 24/145 (16%)
Query: 228 PLCLGTGCSPDNGGCE-----------HECVE-----EVDGHVSCRCTEGFRLAADGRSC 271
PL G G + G E H C E + G C C GF+ A GR+C
Sbjct: 877 PLVCGRGYHANEEGSECVDVNECETGVHRCGEGQLCYNLPGSYRCDCKPGFQRDAFGRTC 936
Query: 272 ED--PCAQAP---CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMC 326
D C +P C+ CE P Y C C GF A D H C D +EC+ C Q C
Sbjct: 937 IDVNECWVSPGRLCQHTCE-NTPGSYRCSCAAGFLLAADGKH-CEDVNECETRR-CSQEC 993
Query: 327 VNYVGGFECYCSEGHELEADGISCS 351
N G ++CYC +G++L DG +C+
Sbjct: 994 ANIYGSYQCYCRQGYQLAEDGHTCT 1018
Score = 54.7 bits (129), Expect = 4e-06
Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 301
C+H C+ V G C C GF L DGR+C P AP P+ S
Sbjct: 606 CQHLCINTV-GSYRCACFPGFELQGDGRTCR-PDRGAPQLDTARESAPRSESAQVSPNTI 663
Query: 302 PAE-DDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
P P+ C D G C+Q+C C C G+ + ADG+SC
Sbjct: 664 PLPVPQPNTCKDN------GPCRQVCRVVGDTAMCSCFPGYAIMADGVSC 707
Score = 48.8 bits (114), Expect = 2e-04
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 296
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 989 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-VNVPGSYQCAC 1046
Query: 297 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 335
+ C D DEC + C + C N G F C
Sbjct: 1047 PEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRC 1088
Score = 46.9 bits (109), Expect = 8e-04
Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 312 DTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSP 352
D DEC + +CQ +C+N VG + C C G EL+ DG +C P
Sbjct: 594 DQDECLMLPGELCQHLCINTVGSYRCACFPGFELQGDGRTCRP 636
Score = 41.8 bits (96), Expect = 0.028
Identities = 39/126 (30%), Positives = 50/126 (38%), Gaps = 26/126 (20%)
Query: 238 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPC---------EQQCEPGG 288
DNG C C V C C G+ + ADG SCED Q C +Q C
Sbjct: 675 DNGPCRQVC-RVVGDTAMCSCFPGYAIMADGVSCED---QDECLMGTHDCSWKQFCVNTL 730
Query: 289 PQGYSCH----CRLGFRPAEDDPHRCVDTDECQI-AGVC--QQMCVNYVGGFECY----C 337
Y + C G+ + +CVD +EC C + CVN G F+CY C
Sbjct: 731 GSFYCVNHTVLCAEGY--ILNAHRKCVDINECVTDLHTCTRAEHCVNTPGSFQCYKALTC 788
Query: 338 SEGHEL 343
G+ L
Sbjct: 789 EPGYVL 794
>ref|NP_032018.1| fibulin 2 [Mus musculus]
sp|P37889|FBL2_MOUSE FIBULIN-2 PRECURSOR
pir||A49457 fibulin-2 precursor - mouse
emb|CAA53040.1| (X75285) fibulin-2 [Mus musculus]
Length = 1221
Score = 91.3 bits (223), Expect = 4e-17
Identities = 51/114 (44%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 950 CQHTC-ENTPGSYRCSCAAGFLLAADGKHCEDVNECETRRCSQECA-NIYGSYQCYCRQG 1007
Query: 300 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 350
++ AED H C D DEC Q AG+ C CVN G ++C C E G+ + A+G SC
Sbjct: 1008 YQLAEDG-HTCTDIDECAQGAGILCTFRCVNVPGSYQCACPEQGYTMMANGRSC 1060
Score = 80.4 bits (195), Expect = 7e-14
Identities = 50/145 (34%), Positives = 65/145 (44%), Gaps = 24/145 (16%)
Query: 228 PLCLGTGCSPDNGGCE-----------HECVE-----EVDGHVSCRCTEGFRLAADGRSC 271
PL G G + G E H C E + G C C GF+ A GR+C
Sbjct: 877 PLVCGRGYHANEEGSECVDVNECETGVHRCGEGQLCYNLPGSYRCDCKPGFQRDAFGRTC 936
Query: 272 ED--PCAQAP---CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMC 326
D C +P C+ CE P Y C C GF A D H C D +EC+ C Q C
Sbjct: 937 IDVNECWVSPGRLCQHTCE-NTPGSYRCSCAAGFLLAADGKH-CEDVNECETRR-CSQEC 993
Query: 327 VNYVGGFECYCSEGHELEADGISCS 351
N G ++CYC +G++L DG +C+
Sbjct: 994 ANIYGSYQCYCRQGYQLAEDGHTCT 1018
Score = 54.7 bits (129), Expect = 4e-06
Identities = 35/110 (31%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 301
C+H C+ V G C C GF L DGR+C P AP P+ S
Sbjct: 606 CQHLCINTV-GSYRCACFPGFELQGDGRTCR-PDRGAPQLDTARESAPRSESAQVSPNTI 663
Query: 302 PAE-DDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
P P+ C D G C+Q+C C C G+ + ADG+SC
Sbjct: 664 PLPVPQPNTCKDN------GPCRQVCRVVGDTAMCSCFPGYAIMADGVSC 707
Score = 48.8 bits (114), Expect = 2e-04
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 296
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 989 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-VNVPGSYQCAC 1046
Query: 297 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 335
+ C D DEC + C + C N G F C
Sbjct: 1047 PEQGYTMMANGRSCKDLDECALGTHNCSEAETCHNIQGSFRC 1088
Score = 46.9 bits (109), Expect = 8e-04
Identities = 19/43 (44%), Positives = 26/43 (60%), Gaps = 2/43 (4%)
Query: 312 DTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSP 352
D DEC + +CQ +C+N VG + C C G EL+ DG +C P
Sbjct: 594 DQDECLMLPGELCQHLCINTVGSYRCACFPGFELQGDGRTCRP 636
Score = 41.8 bits (96), Expect = 0.028
Identities = 39/126 (30%), Positives = 50/126 (38%), Gaps = 26/126 (20%)
Query: 238 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPC---------EQQCEPGG 288
DNG C C V C C G+ + ADG SCED Q C +Q C
Sbjct: 675 DNGPCRQVC-RVVGDTAMCSCFPGYAIMADGVSCED---QDECLMGTHDCSWKQFCVNTL 730
Query: 289 PQGYSCH----CRLGFRPAEDDPHRCVDTDECQI-AGVC--QQMCVNYVGGFECY----C 337
Y + C G+ + +CVD +EC C + CVN G F+CY C
Sbjct: 731 GSFYCVNHTVLCAEGY--ILNAHRKCVDINECVTDLHTCTRAEHCVNTPGSFQCYKALTC 788
Query: 338 SEGHEL 343
G+ L
Sbjct: 789 EPGYVL 794
>emb|CAB43267.1| (AL050095) hypothetical protein [Homo sapiens]
Length = 576
Score = 89.7 bits (219), Expect = 1e-16
Identities = 50/114 (43%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 305 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECA-NIYGSYQCYCRQG 362
Query: 300 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 350
++ AED H C D DEC Q AG+ C C+N G ++C C E G+ + A+G SC
Sbjct: 363 YQLAEDG-HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 415
Score = 76.9 bits (186), Expect = 8e-13
Identities = 50/133 (37%), Positives = 63/133 (46%), Gaps = 17/133 (12%)
Query: 232 GTGCSPDNGGCE---HECVE-----EVDGHVSCRCTEGFRLAADGRSCED--PCAQAP-- 279
GT C D CE H C E + G C C GF+ A GR C D C +P
Sbjct: 245 GTKCV-DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGR 303
Query: 280 -CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCS 338
C+ CE Y C C GF A D RC D +EC+ A C Q C N G ++CYC
Sbjct: 304 LCQHTCE-NTLGSYRCSCASGFLLAADGK-RCEDVNECE-AQRCSQECANIYGSYQCYCR 360
Query: 339 EGHELEADGISCS 351
+G++L DG +C+
Sbjct: 361 QGYQLAEDGHTCT 373
Score = 59.3 bits (141), Expect = 1e-07
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 246 CVEEVDGHVSCR----CTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----PQGYSCHC 296
C+ V + R C G+ + DG C D +C G P Y C C
Sbjct: 219 CINTVGSYTCQRNPLICARGYHASDDGTKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 278
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG--VCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 354
+ GF+ + C+D +EC + +CQ C N +G + C C+ G L ADG C
Sbjct: 279 KAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 337
Query: 355 AMGAQ 359
AQ
Sbjct: 338 ECEAQ 342
Score = 49.2 bits (115), Expect = 2e-04
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 296
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 344 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-LNVPGSYQCAC 401
Query: 297 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 335
+ C D DEC + C + C N G F C
Sbjct: 402 PEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 443
Score = 48.0 bits (112), Expect = 4e-04
Identities = 41/142 (28%), Positives = 56/142 (38%), Gaps = 20/142 (14%)
Query: 238 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDP---------CAQAP-CEQQCEPG 287
DNG C+ C V G C C G+ + ADG SCED C++ C
Sbjct: 30 DNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVNTLGSF 88
Query: 288 GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECY----CSEG 340
++ C G+ + +CVD +EC C + CVN +G F CY C G
Sbjct: 89 YCVNHTVLCADGY--ILNAHRKCVDINECVTDLHTCSRGEHCVNTLGSFHCYKALTCEPG 146
Query: 341 HELEADGISCSPAGAMGAQASQ 362
+ L+ AMG Q
Sbjct: 147 YALKDGECEDVDECAMGTHTCQ 168
Score = 36.0 bits (81), Expect = 1.6
Identities = 14/35 (40%), Positives = 20/35 (57%)
Query: 316 CQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
C+ G C+Q+C G C C G+ + ADG+SC
Sbjct: 28 CKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 62
>ref|NP_001989.1| fibulin 2 precursor; Fibulin-2 [Homo sapiens]
sp|P98095|FBL2_HUMAN FIBULIN-2 PRECURSOR
pir||A55184 fibulin-2 precursor - human
emb|CAA57876.1| (X82494) fibulin-2 [Homo sapiens]
Length = 1184
Score = 89.7 bits (219), Expect = 1e-16
Identities = 50/114 (43%), Positives = 63/114 (54%), Gaps = 8/114 (7%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C+H C E G C C GF LAADG+ CED C C Q+C Y C+CR G
Sbjct: 913 CQHTC-ENTLGSYRCSCASGFLLAADGKRCEDVNECEAQRCSQECA-NIYGSYQCYCRQG 970
Query: 300 FRPAEDDPHRCVDTDEC-QIAGV-CQQMCVNYVGGFECYCSE-GHELEADGISC 350
++ AED H C D DEC Q AG+ C C+N G ++C C E G+ + A+G SC
Sbjct: 971 YQLAEDG-HTCTDIDECAQGAGILCTFRCLNVPGSYQCACPEQGYTMTANGRSC 1023
Score = 75.3 bits (182), Expect = 2e-12
Identities = 47/127 (37%), Positives = 60/127 (47%), Gaps = 16/127 (12%)
Query: 238 DNGGCE---HECVE-----EVDGHVSCRCTEGFRLAADGRSCED--PCAQAP---CEQQC 284
D CE H C E + G C C GF+ A GR C D C +P C+ C
Sbjct: 858 DVNECETGVHRCGEGQVCHNLPGSYRCDCKAGFQRDAFGRGCIDVNECWASPGRLCQHTC 917
Query: 285 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELE 344
E Y C C GF A D RC D +EC+ A C Q C N G ++CYC +G++L
Sbjct: 918 E-NTLGSYRCSCASGFLLAADGK-RCEDVNECE-AQRCSQECANIYGSYQCYCRQGYQLA 974
Query: 345 ADGISCS 351
DG +C+
Sbjct: 975 EDGHTCT 981
Score = 59.3 bits (141), Expect = 1e-07
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 12/125 (9%)
Query: 246 CVEEVDGHVSCR----CTEGFRLAADGRSCEDPCAQAPCEQQCEPGG-----PQGYSCHC 296
C+ V + R C G+ + DG C D +C G P Y C C
Sbjct: 827 CINTVGSYTCQRNPLICARGYHASDDGAKCVDVNECETGVHRCGEGQVCHNLPGSYRCDC 886
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG--VCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 354
+ GF+ + C+D +EC + +CQ C N +G + C C+ G L ADG C
Sbjct: 887 KAGFQ-RDAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCASGFLLAADGKRCEDVN 945
Query: 355 AMGAQ 359
AQ
Sbjct: 946 ECEAQ 950
Score = 57.8 bits (137), Expect = 4e-07
Identities = 34/109 (31%), Positives = 47/109 (42%), Gaps = 7/109 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFR 301
C+H C+ V G C C GF L DGR+C P P +P PQ +
Sbjct: 616 CQHLCINTV-GSYHCACFPGFSLQDDGRTCR-PEGHPP-----QPEAPQEPALKSEFSQV 668
Query: 302 PAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ P + C+ G C+Q+C G C C G+ + ADG+SC
Sbjct: 669 ASNTIPLPLPQPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSC 717
Score = 49.2 bits (115), Expect = 2e-04
Identities = 33/102 (32%), Positives = 42/102 (40%), Gaps = 10/102 (9%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQGYSCHC 296
C EC + G C C +G++LA DG +C D CAQ C +C P Y C C
Sbjct: 952 CSQECAN-IYGSYQCYCRQGYQLAEDGHTCTDIDECAQGAGILCTFRC-LNVPGSYQCAC 1009
Query: 297 RLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFEC 335
+ C D DEC + C + C N G F C
Sbjct: 1010 PEQGYTMTANGRSCKDVDECALGTHNCSEAETCHNIQGSFRC 1051
Score = 48.8 bits (114), Expect = 2e-04
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 8/106 (7%)
Query: 253 HVSCRCTEGFR--LAADGRSCEDPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 310
HV C EG + + R +P A + E G + S LG +
Sbjct: 547 HVMLSCCEGEEPLIVPEVRRPPEPAAAPRRVSEAEMAGREALS----LGTEAELPNSLPG 602
Query: 311 VDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISCSPAG 354
D DEC + +CQ +C+N VG + C C G L+ DG +C P G
Sbjct: 603 DDQDECLLLPGELCQHLCINTVGSYHCACFPGFSLQDDGRTCRPEG 648
Score = 46.5 bits (108), Expect = 0.001
Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 20/126 (15%)
Query: 238 DNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGY 292
DNG C+ C V G C C G+ + ADG SCED C G +
Sbjct: 685 DNGPCKQVC-STVGGSAICSCFPGYAIMADGVSCEDINECVTDLHTCSRGEHCVNTLGSF 743
Query: 293 SCH----CRLGFRPAEDDPHRCVDTDECQI-AGVCQQ--MCVNYVGGFECY----CSEGH 341
C+ C G+ + + C D DEC + CQ +C N G F C C +G
Sbjct: 744 HCYKALTCEPGYALKDGE---CEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDGF 800
Query: 342 ELEADG 347
+ +G
Sbjct: 801 LQDPEG 806
>emb|CAB62995.1| (Z98047) dJ162H14.1 (Fibulin 1) [Homo sapiens]
Length = 554
Score = 88.5 bits (216), Expect = 2e-16
Identities = 44/115 (38%), Positives = 63/115 (54%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E G C C+ GFRL+ DGRSCE + C+ +PC Q+C Y C+CR G
Sbjct: 384 CGHKC-ENTLGSYLCSCSVGFRLSVDGRSCEGINECSSSPCSQEC-ANVYGSYQCYCRRG 441
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C DEC + +C C+N G F+C C S G+ L +G +C
Sbjct: 442 YQLSDVDGVTCEGIDECALPTGGHICSYRCINIPGSFQCSCPSSGYRLAPNGRNC 496
Score = 57.4 bits (136), Expect = 6e-07
Identities = 39/136 (28%), Positives = 56/136 (40%), Gaps = 17/136 (12%)
Query: 230 CLGTG-CSPDNGGCE--HECVEEVDGHVSCR-----CTEGFRLAADGRSCEDPCAQAPCE 281
C+G C + C H C+ +G +C+ C G+ L +G C AP
Sbjct: 279 CIGINECLSISAPCPIGHTCIN-TEGSYTCQKNVPNCGRGYHLNEEGTRCVGVDECAPPA 337
Query: 282 QQCEPG-----GPQGYSCHCRLGFRPAEDDPHRCVDTDECQI--AGVCQQMCVNYVGGFE 334
+ C G P + C C+ G+ + CV +ECQ +C C N +G +
Sbjct: 338 EPCGKGHRCVNSPGSFRCECKTGYY-FDGISRMCVGVNECQRYPGRLCGHKCENTLGSYL 396
Query: 335 CYCSEGHELEADGISC 350
C CS G L DG SC
Sbjct: 397 CSCSVGFRLSVDGRSC 412
Score = 40.2 bits (92), Expect = 0.083
Identities = 36/125 (28%), Positives = 51/125 (40%), Gaps = 21/125 (16%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGP-----QGYSC 294
G C+ +C + D V C C G++L +DG SCE C G + C
Sbjct: 157 GPCKQQCRDTGD-EVVCSCFVGYQLLSDGVSCEGVNECITGSHSCRLGESCINTVGSFRC 215
Query: 295 H----CRLGFRPAEDDPHRCVDTDECQIAGV--C--QQMCVNYVGGFEC----YCSEGHE 342
C G+ ED + C DEC+ +G+ C +C N +G F C C G
Sbjct: 216 QRDSSCGTGYELTED--NSCKGIDECE-SGIHNCLPDFICQNTLGSFRCRPKLQCKSGFI 272
Query: 343 LEADG 347
+A G
Sbjct: 273 QDALG 277
Score = 36.4 bits (82), Expect = 1.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 304 EDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++DP+ D C+ G C+Q C + C C G++L +DG+SC
Sbjct: 144 QEDPYL---NDRCRGGGPCKQQCRDTGDEVVCSCFVGYQLLSDGVSC 187
Score = 33.6 bits (75), Expect = 8.2
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 7/55 (12%)
Query: 227 GPLCLGTG-CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCE--DPC 275
G C G C+ GG C + C+ + G C C + G+RLA +GR+C+ D C
Sbjct: 449 GVTCEGIDECALPTGGHICSYRCIN-IPGSFQCSCPSSGYRLAPNGRNCQGIDEC 502
>ref|NP_058042.1| matrilin 2 [Mus musculus]
sp|O08746|MTN2_MOUSE MATRILIN-2 PRECURSOR
gb|AAC53163.1| (U69262) matrilin-2 precursor [Mus musculus]
Length = 956
Score = 88.5 bits (216), Expect = 2e-16
Identities = 48/122 (39%), Positives = 64/122 (52%), Gaps = 8/122 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C+ + GCEHECV +GH CRC +G+ L +G++C D CAQ CEQ C +
Sbjct: 406 CALNKPGCEHECVNTEEGHY-CRCRQGYNLDPNGKTCSRVDHCAQQDHGCEQLCL-NTEE 463
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C GF DD C D C ++ C+ CVN F C C EGH L +DG +
Sbjct: 464 SFVCQCSEGFL-INDDLKTCSRADYCLLSNHGCEYSCVNTDKSFACQCPEGHVLRSDGKT 522
Query: 350 CS 351
C+
Sbjct: 523 CA 524
Score = 83.5 bits (203), Expect = 8e-15
Identities = 54/139 (38%), Positives = 66/139 (46%), Gaps = 8/139 (5%)
Query: 217 PEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDP 274
PEG V S C+ + GCEH CV D V C+C EG+ L DG++C +D
Sbjct: 511 PEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFV-CQCFEGYILRDDGKTCRRKDV 569
Query: 275 CAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVG 331
C CE C G + Y C C GFR AED RC + C+ C+ MCVN
Sbjct: 570 CQDVNHGCEHLCVNSG-ESYVCKCLEGFRLAEDGK-RCRRKNVCKSTQHGCEHMCVNNGN 627
Query: 332 GFECYCSEGHELEADGISC 350
+ C CSEG L DG C
Sbjct: 628 SYLCRCSEGFVLAEDGKHC 646
Score = 75.3 bits (182), Expect = 2e-12
Identities = 44/124 (35%), Positives = 63/124 (50%), Gaps = 8/124 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCA--QAPCEQQCEPGGPQ 290
C+ N GC+HECV + CRC +GF L D ++C + CA + CE +C +
Sbjct: 365 CASSNHGCQHECVNAQTSAL-CRCLKGFMLNPDRKTCRRINYCALNKPGCEHECV-NTEE 422
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGIS 349
G+ C CR G+ + + C D C Q C+Q+C+N F C CSEG + D +
Sbjct: 423 GHYCRCRQGYN-LDPNGKTCSRVDHCAQQDHGCEQLCLNTEESFVCQCSEGFLINDDLKT 481
Query: 350 CSPA 353
CS A
Sbjct: 482 CSRA 485
Score = 71.0 bits (171), Expect = 5e-11
Identities = 43/121 (35%), Positives = 55/121 (44%), Gaps = 8/121 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C N GCE+ CV D +C+C EG L +DG++C D CA CE C
Sbjct: 488 CLLSNHGCEYSCVN-TDKSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSC-VSSED 545
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C G+ DD C D CQ + C+ +CVN + C C EG L DG
Sbjct: 546 SFVCQCFEGY-ILRDDGKTCRRKDVCQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKR 604
Query: 350 C 350
C
Sbjct: 605 C 605
Score = 65.2 bits (156), Expect = 3e-09
Identities = 42/128 (32%), Positives = 58/128 (44%), Gaps = 8/128 (6%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQC 284
LC CS C H C+ ++ C+C +G+ L+ D ++C +D CA CEQ C
Sbjct: 236 LCTVHMCSVLEHNCAHFCLNTPGSYI-CKCKQGYILSTDQKTCRIQDLCATEDHGCEQLC 294
Query: 285 EPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHEL 343
+ C C G+ AED RC D C C+ CVN + C C EG L
Sbjct: 295 V-NMLGSFVCQCYSGYTLAEDGK-RCTAMDYCASENHGCEHECVNAESSYLCRCHEGFAL 352
Query: 344 EADGISCS 351
+D +CS
Sbjct: 353 NSDKKTCS 360
Score = 46.5 bits (108), Expect = 0.001
Identities = 30/88 (34%), Positives = 39/88 (44%), Gaps = 11/88 (12%)
Query: 203 CQ-AGRGASLLCVKQPEG-------GVGWSRAGPLCLGTG-CSPDNGGCEHECVEEVDGH 253
CQ G LCV E G + G C C GCEH CV + +
Sbjct: 570 CQDVNHGCEHLCVNSGESYVCKCLEGFRLAEDGKRCRRKNVCKSTQHGCEHMCVNNGNSY 629
Query: 254 VSCRCTEGFRLAADGRSCEDPCAQAPCE 281
+ CRC+EGF LA DG+ C+ C + P +
Sbjct: 630 L-CRCSEGFVLAEDGKHCK-RCTEGPID 655
>gb|AAB80944.1| (AF013751) fibulin-1 D [Danio rerio]
Length = 681
Score = 86.6 bits (211), Expect = 9e-16
Identities = 45/115 (39%), Positives = 61/115 (52%), Gaps = 8/115 (6%)
Query: 242 CEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGPQGYSCHCRLG 299
C H+C E + G C CT GF+LA DGR+C+D C +PC Q C Y +CR G
Sbjct: 386 CAHKC-ENILGSYKCSCTAGFKLADDGRNCDDVNECESSPCSQGC-ANVYGSYQSYCRRG 443
Query: 300 FRPAEDDPHRCVDTDECQI---AGVCQQMCVNYVGGFECYC-SEGHELEADGISC 350
++ ++ D C D DEC + +C C N G F C C + G+ L A+G SC
Sbjct: 444 YQLSDADGITCEDIDECALPTGGHICSYRCHNTPGSFHCTCPASGYTLAANGRSC 498
Score = 79.2 bits (192), Expect = 2e-13
Identities = 47/120 (39%), Positives = 60/120 (49%), Gaps = 10/120 (8%)
Query: 237 PDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQCEPGGPQG 291
PDN H C+ V G C C GF + RSCE D C P C +CE
Sbjct: 339 PDNSCDGHGCINLV-GSYRCECRTGFIFNSISRSCEDIDECRNYPGRLCAHKCE-NILGS 396
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHEL-EADGISC 350
Y C C GF+ A DD C D +EC+ + C Q C N G ++ YC G++L +ADGI+C
Sbjct: 397 YKCSCTAGFKLA-DDGRNCDDVNECE-SSPCSQGCANVYGSYQSYCRRGYQLSDADGITC 454
Score = 56.6 bits (134), Expect = 1e-06
Identities = 33/102 (32%), Positives = 45/102 (43%), Gaps = 7/102 (6%)
Query: 255 SCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGG----PQGYSCHCRLGFRPAEDDPHRC 310
S C G+ L A+G C D A + C+ G Y C CR GF C
Sbjct: 314 SVTCGRGYHLNAEGTRCVDIDECAGPDNSCDGHGCINLVGSYRCECRTGFI-FNSISRSC 372
Query: 311 VDTDECQI--AGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
D DEC+ +C C N +G ++C C+ G +L DG +C
Sbjct: 373 EDIDECRNYPGRLCAHKCENILGSYKCSCTAGFKLADDGRNC 414
Score = 54.7 bits (129), Expect = 4e-06
Identities = 52/176 (29%), Positives = 65/176 (36%), Gaps = 31/176 (17%)
Query: 194 PFGSVAAVQCQAGRGASLLCV-KQPEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDG 252
P SV G G CV KQP GV S+ C GC C+
Sbjct: 120 PVSSVCRWSISRGPGVRSCCVDKQPAHGVQPSKGDAQNTEDQCRA--AGCAQRCLNG--- 174
Query: 253 HVSCRCTEGFRLAADGRSCED--PCAQAPCEQQCEPGGP-----QGYSCH----CRLGFR 301
+C C +GF+L DG+ CED C P C G Y C C G+
Sbjct: 175 --TCSCLDGFKLKTDGKHCEDINECLLGP--HHCVTGERCINTLGSYRCQREISCGTGYE 230
Query: 302 PAEDDPHRCVDTDECQIAG---VCQQMCVNYVGGFEC----YCSEGHELEADGISC 350
D ++C D DEC + + C N G F C C+ G +A G SC
Sbjct: 231 LT--DNNKCKDIDECDLGTHNCAAEMECQNTAGSFRCRPRMQCAAGFIQDALG-SC 283
Score = 34.0 bits (76), Expect = 6.2
Identities = 29/107 (27%), Positives = 40/107 (37%), Gaps = 12/107 (11%)
Query: 235 CSPDNGG--CEHECVEEVDGHVSCRC-TEGFRLAADGRSCEDPCAQAPCEQQCE------ 285
C+ GG C + C G C C G+ LAA+GRSC+D C
Sbjct: 460 CALPTGGHICSYRC-HNTPGSFHCTCPASGYTLAANGRSCQDIDECLTGTHSCSESESCF 518
Query: 286 --PGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYV 330
GG + S C +R + D R D + CQ ++ V
Sbjct: 519 NIQGGFRCLSFDCPANYRRSGDTRPRVDRADIIRCVKSCQHNDISCV 565
>gb|AAD41769.1|AF112153_1 (AF112153) developmental arteries and neural crest EGF-like protein
[Rattus norvegicus]
Length = 448
Score = 85.0 bits (207), Expect = 3e-15
Identities = 46/119 (38%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 235 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 292
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
SC C GF DD C D +EC+ C Q CVN G F C C G+ELE DGI CS
Sbjct: 189 SCTCNPGFT-LNDDGRSCQDVNECETENPCVQTCVNTYGSFICRCDPGYELEEDGIHCS 246
Score = 76.5 bits (185), Expect = 1e-12
Identities = 46/115 (40%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQAPCEQQCEPGGPQGYSCHC 296
G C+ C V G SC C GF L DGRSC+D C + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNDDGRSCQDVNECETENPCVQTCV-NTYGSFICRC 232
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 350
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGIH-CSDMDECSFSEFLCQHECVNQPGSYFCSCPPGYVLLEDNRSC 286
Score = 42.2 bits (97), Expect = 0.021
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 296 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 343
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DEGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
Score = 40.2 bits (92), Expect = 0.083
Identities = 34/129 (26%), Positives = 41/129 (31%), Gaps = 41/129 (31%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 294
CS C+HECV + G C C G+ L D RSC+D
Sbjct: 251 CSFSEFLCQHECVNQ-PGSYFCSCPPGYVLLEDNRSCQD--------------------- 288
Query: 295 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFEC----YCSEGHELEADGISC 350
E H C Q C N GGF+C C E + L D
Sbjct: 289 -----INECEHRNHTCTPL----------QTCYNLQGGFKCIDPIVCEEPYLLIGDNRCM 333
Query: 351 SPAGAMGAQ 359
PA G +
Sbjct: 334 CPAENTGCR 342
>ref|NP_035942.1| fibulin 5 [Mus musculus]
sp|Q9WVH9|FBL5_MOUSE FIBULIN-5 PRECURSOR (FIBL-5) (DEVELOPMENTAL ARTERIES AND NEURAL
CREST EGF-LIKE PROTEIN) (DANCE)
gb|AAD41767.1|AF112151_1 (AF112151) developmental arteries and neural crest EGF-like protein
[Mus musculus]
Length = 448
Score = 85.0 bits (207), Expect = 3e-15
Identities = 46/119 (38%), Positives = 57/119 (47%), Gaps = 5/119 (4%)
Query: 235 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 292
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
SC C GF DD C D +EC+ C Q CVN G F C C G+ELE DGI CS
Sbjct: 189 SCTCNPGFT-LNDDGRSCQDVNECETENPCVQTCVNTYGSFICRCDPGYELEEDGIHCS 246
Score = 76.1 bits (184), Expect = 1e-12
Identities = 46/115 (40%), Positives = 55/115 (47%), Gaps = 7/115 (6%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQAPCEQQCEPGGPQGYSCHC 296
G C+ C V G SC C GF L DGRSC+D C + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNDDGRSCQDVNECETENPCVQTCV-NTYGSFICRC 232
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 350
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGIH-CSDMDECSFSEFLCQHECVNQPGSYFCSCPPGYVLLDDNRSC 286
Score = 53.5 bits (126), Expect = 9e-06
Identities = 40/130 (30%), Positives = 52/130 (39%), Gaps = 15/130 (11%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 290
C +N C CV G CRC G+ L DG C D ++ C+ +C P
Sbjct: 211 CETENP-CVQTCVNTY-GSFICRCDPGYELEEDGIHCSDMDECSFSEFLCQHECV-NQPG 267
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAG---VCQQMCVNYVGGFECY----CSEGHEL 343
Y C C G+ DD C D +EC+ Q C N GGF+C C E + L
Sbjct: 268 SYFCSCPPGY-VLLDDNRSCQDINECEHRNHTCTSLQTCYNLQGGFKCIDPISCEEPYLL 326
Query: 344 EADGISCSPA 353
+ PA
Sbjct: 327 IGENRCMCPA 336
Score = 42.2 bits (97), Expect = 0.021
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 296 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 343
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DEGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
>ref|NP_066025.1| CEGP1 protein [Homo sapiens]
emb|CAB92285.1| (AJ400877) CEGP1 protein [Homo sapiens]
Length = 999
Score = 83.1 bits (202), Expect = 1e-14
Identities = 45/120 (37%), Positives = 63/120 (52%), Gaps = 8/120 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQG 291
C NGGC+H C + + G C C +GF+L D +SC+D C+ C+ C P
Sbjct: 327 CQTRNGGCDHFC-KNIVGSFDCGCKKGFKLLTDEKSCQDVDECSLDRTCDHSCI-NHPGT 384
Query: 292 YSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
++C C G+ C DT+EC I G CQQ+CVN VG +EC C G++L + C
Sbjct: 385 FACACNRGYTLYGFT--HCGDTNECSINNGGCQQVCVNTVGSYECQCHPGYKLHWNKKDC 442
Score = 78.8 bits (191), Expect = 2e-13
Identities = 38/113 (33%), Positives = 56/113 (48%), Gaps = 7/113 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED----PCAQAPCEQQCEPGGPQ 290
C+ +NGGC+ C + G V C C GF L DG++C+D C+ C+
Sbjct: 286 CAVNNGGCDRTCKDTSTG-VHCSCPVGFTLQLDGKTCKDIDECQTRNGGCDHFCK-NIVG 343
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHEL 343
+ C C+ GF+ D+ C D DEC + C C+N+ G F C C+ G+ L
Sbjct: 344 SFDCGCKKGFKLLTDEKS-CQDVDECSLDRTCDHSCINHPGTFACACNRGYTL 395
Score = 64.8 bits (155), Expect = 3e-09
Identities = 39/101 (38%), Positives = 48/101 (46%), Gaps = 10/101 (9%)
Query: 256 CRCTEGFRLAADGRSCED--PCAQ---APCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRC 310
C C G++ +GR CED C C C P Y C C GF A D H C
Sbjct: 71 CSCKPGYQ--GEGRQCEDIDECGNELNGGCVHDCL-NIPGNYRCTCFDGFMLAHDG-HNC 126
Query: 311 VDTDEC-QIAGVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+D DEC + G CQ CVN +G +EC C EG L + +C
Sbjct: 127 LDVDECLENNGGCQHTCVNVMGSYECCCKEGFFLSDNQHTC 167
Score = 63.6 bits (152), Expect = 8e-09
Identities = 40/125 (32%), Positives = 55/125 (44%), Gaps = 13/125 (10%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQA--------PCEQQCEP 286
C +NGGC+H CV V G C C EGF L+ + +C + C C+
Sbjct: 132 CLENNGGCQHTCV-NVMGSYECCCKEGFFLSDNQHTCIHRSEEGLSCMNKDHGCSHICKE 190
Query: 287 GGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEA 345
+C CR GF A++ C+ T C G CQ C + G EC C +++
Sbjct: 191 APRGSVACECRPGFELAKNQ-RDCILT--CNHGNGGCQHSCDDTADGPECSCHPQYKMHT 247
Query: 346 DGISC 350
DG SC
Sbjct: 248 DGRSC 252
Score = 58.6 bits (139), Expect = 3e-07
Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 13/122 (10%)
Query: 239 NGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDPCAQ--APCEQQCEPGGPQGYSC 294
NGGC H+C+ + G+ C C +GF LA DG +C D C + C+ C Y C
Sbjct: 95 NGGCVHDCLN-IPGNYRCTCFDGFMLAHDGHNCLDVDECLENNGGCQHTC-VNVMGSYEC 152
Query: 295 HCRLGFRPAEDDPHRCVDTDECQIAGV-----CQQMCVNYV-GGFECYCSEGHELEADGI 348
C+ GF D+ H C+ E ++ + C +C G C C G EL +
Sbjct: 153 CCKEGFF-LSDNQHTCIHRSEEGLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQR 211
Query: 349 SC 350
C
Sbjct: 212 DC 213
Score = 54.7 bits (129), Expect = 4e-06
Identities = 37/150 (24%), Positives = 53/150 (34%), Gaps = 33/150 (22%)
Query: 232 GTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPC--AQAPCEQQCEPGGP 289
G C + GC H C E G V+C C GF LA + R C C C+ C+
Sbjct: 174 GLSCMNKDHGCSHICKEAPRGSVACECRPGFELAKNQRDCILTCNHGNGGCQHSCDDTA- 232
Query: 290 QGYSCHCRLGFRPAEDDPHRCVDTDE----------------------------CQI-AG 320
G C C ++ D C++ ++ C + G
Sbjct: 233 DGPECSCHPQYK-MHTDGRSCLEREDTVLEVTESNTTSVVDGDKRVKRRLLMETCAVNNG 291
Query: 321 VCQQMCVNYVGGFECYCSEGHELEADGISC 350
C + C + G C C G L+ DG +C
Sbjct: 292 GCDRTCKDTSTGVHCSCPVGFTLQLDGKTC 321
>emb|CAB70853.1| (AL137638) hypothetical protein [Homo sapiens]
Length = 741
Score = 82.3 bits (200), Expect = 2e-14
Identities = 53/139 (38%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
Query: 217 PEGGVGWSRAGPLCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSC--EDP 274
PEG V S C+ + GCEH CV D V C+C EG+ L DG++C +D
Sbjct: 296 PEGHVLRSDGKTCAKLDSCALGDHGCEHSCVSSEDSFV-CQCFEGYILREDGKTCRRKDV 354
Query: 275 CAQAP--CEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVG 331
C CE C Y+C C GFR AED RC D C+ C+ +CVN
Sbjct: 355 CQAIDHGCEHICV-NSDDSYTCECLEGFRLAEDGK-RCRRKDVCKSTHHGCEHICVNNGN 412
Query: 332 GFECYCSEGHELEADGISC 350
+ C CSEG L DG C
Sbjct: 413 SYICKCSEGFVLAEDGRRC 431
Score = 79.6 bits (193), Expect = 1e-13
Identities = 45/122 (36%), Positives = 61/122 (49%), Gaps = 8/122 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C+ + GCEHECV + + CRC G+ L +G++C D CAQ CEQ C
Sbjct: 191 CALNKPGCEHECVNMEESYY-CRCHRGYTLDPNGKTCSRVDHCAQQDHGCEQLCL-NTED 248
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C GF +D C D C ++ C+ CVN F C C EGH L +DG +
Sbjct: 249 SFVCQCSEGFL-INEDLKTCSRVDYCLLSDHGCEYSCVNMDRSFACQCPEGHVLRSDGKT 307
Query: 350 CS 351
C+
Sbjct: 308 CA 309
Score = 69.9 bits (168), Expect = 1e-10
Identities = 45/129 (34%), Positives = 57/129 (43%), Gaps = 10/129 (7%)
Query: 231 LGTGCSPDNGGCEHECVE---EVDGHVSCRCTEGFRLAADGRSC--EDPCAQAP--CEQQ 283
LG P EH C + G CRC +G+ L +D +C +D CA CEQ
Sbjct: 19 LGEAKRPTRKTLEHNCAHFCINIPGSYVCRCKQGYILNSDQTTCRIQDLCAMEDHNCEQL 78
Query: 284 CEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHE 342
C P + C C G+ AED RCV D C C+ CVN G + C C EG
Sbjct: 79 CV-NVPGSFVCQCYSGYALAEDGK-RCVAVDYCASENHGCEHECVNADGSYLCQCHEGFA 136
Query: 343 LEADGISCS 351
L D +C+
Sbjct: 137 LNPDEKTCT 145
Score = 69.1 bits (166), Expect = 2e-10
Identities = 43/121 (35%), Positives = 56/121 (45%), Gaps = 8/121 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C + GCE+ CV +D +C+C EG L +DG++C D CA CE C
Sbjct: 273 CLLSDHGCEYSCVN-MDRSFACQCPEGHVLRSDGKTCAKLDSCALGDHGCEHSC-VSSED 330
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQ-IAGVCQQMCVNYVGGFECYCSEGHELEADGIS 349
+ C C G+ ED C D CQ I C+ +CVN + C C EG L DG
Sbjct: 331 SFVCQCFEGYILREDG-KTCRRKDVCQAIDHGCEHICVNSDDSYTCECLEGFRLAEDGKR 389
Query: 350 C 350
C
Sbjct: 390 C 390
Score = 67.1 bits (161), Expect = 7e-10
Identities = 41/121 (33%), Positives = 53/121 (42%), Gaps = 8/121 (6%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP--CEQQCEPGGPQ 290
C+ ++ CE CV V G C+C G+ LA DG+ C D CA CE +C
Sbjct: 68 CAMEDHNCEQLCVN-VPGSFVCQCYSGYALAEDGKRCVAVDYCASENHGCEHECV-NADG 125
Query: 291 GYSCHCRLGFRPAEDDPHRCVDTDECQIAGV-CQQMCVNYVGGFECYCSEGHELEADGIS 349
Y C C GF D C D C + CQ CVN + C+C +G L D +
Sbjct: 126 SYLCQCHEGFA-LNPDEKTCTKIDYCASSNHGCQHECVNTDDSYSCHCLKGFTLNPDKKT 184
Query: 350 C 350
C
Sbjct: 185 C 185
Score = 46.9 bits (109), Expect = 8e-04
Identities = 20/47 (42%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCE 281
C + GCEH CV + ++ C+C+EGF LA DGR C+ C + P +
Sbjct: 396 CKSTHHGCEHICVNNGNSYI-CKCSEGFVLAEDGRRCK-KCTEGPID 440
>ref|NP_062026.1| fibulin 5 [Rattus norvegicus]
gb|AAD25101.1|AF137350_1 (AF137350) embryonic vascular EGF repeat-containing protein EVEC
[Rattus norvegicus]
Length = 448
Score = 82.3 bits (200), Expect = 2e-14
Identities = 45/119 (37%), Positives = 56/119 (46%), Gaps = 5/119 (4%)
Query: 235 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 292
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
SC C GF DD C D +EC+ C Q CVN G F C C G+E E DGI CS
Sbjct: 189 SCTCNPGFT-LNDDGRSCQDVNECETENPCVQTCVNTYGSFICRCDPGYEPEEDGIHCS 246
Score = 80.4 bits (195), Expect = 7e-14
Identities = 47/115 (40%), Positives = 56/115 (47%), Gaps = 7/115 (6%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PC-AQAPCEQQCEPGGPQGYSCHC 296
G C+ C V G SC C GF L DGRSC+D C + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNDDGRSCQDVNECETENPCVQTCV-NTYGSFICRC 232
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 350
G+ P ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYEPEEDGIH-CSDMDECSFSEFLCQHECVNQPGSYFCSCPPGYVLLEDNRSC 286
Score = 42.2 bits (97), Expect = 0.021
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 296 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 343
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DEGNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
Score = 40.2 bits (92), Expect = 0.083
Identities = 34/129 (26%), Positives = 41/129 (31%), Gaps = 41/129 (31%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 294
CS C+HECV + G C C G+ L D RSC+D
Sbjct: 251 CSFSEFLCQHECVNQ-PGSYFCSCPPGYVLLEDNRSCQD--------------------- 288
Query: 295 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFEC----YCSEGHELEADGISC 350
E H C Q C N GGF+C C E + L D
Sbjct: 289 -----INECEHRNHTCTPL----------QTCYNLQGGFKCIDPIVCEEPYLLIGDNRCM 333
Query: 351 SPAGAMGAQ 359
PA G +
Sbjct: 334 CPAENTGCR 342
>emb|CAB38568.1| (AJ133490) fibulin-5 [Homo sapiens]
gb|AAD41768.1|AF112152_1 (AF112152) developmental arteries and neural crest EGF-like protein
[Homo sapiens]
Length = 448
Score = 81.9 bits (199), Expect = 2e-14
Identities = 45/119 (37%), Positives = 56/119 (46%), Gaps = 5/119 (4%)
Query: 235 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 292
C+ D+ C C+ +G +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICIN-TEGGYTCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
SC C GF ED C D +EC C Q CVN G F C C G+ELE DG+ CS
Sbjct: 189 SCTCNPGFTLNEDG-RSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCS 246
Score = 77.3 bits (187), Expect = 6e-13
Identities = 47/115 (40%), Positives = 56/115 (47%), Gaps = 7/115 (6%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQGYSCHC 296
G C+ C V G SC C GF L DGRSC+D CA + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCV-NTYGSFICRC 232
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 350
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGVH-CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 42.6 bits (98), Expect = 0.016
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 296 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 343
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DESNQCVDVDECATDSHQCNPTQICINTEGGYTCSCTDGYWL 161
Score = 39.1 bits (89), Expect = 0.19
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 41/129 (31%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 294
CS C+HECV + G C C G+ L D RSC+D +CE + ++C
Sbjct: 251 CSFSEFLCQHECVNQ-PGTYFCSCPPGYILLDDNRSCQD-------INECE---HRNHTC 299
Query: 295 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECY----CSEGHELEADGISC 350
+ QQ C N GGF+C C E + +D
Sbjct: 300 N--------------------------LQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Query: 351 SPAGAMGAQ 359
PA G +
Sbjct: 334 CPAENPGCR 342
>pir||T22793 hypothetical protein F56H11.1 - Caenorhabditis elegans
emb|CAA92962.1| (Z68749) Similarity to Mouse fibrilin-2 (SW:FBL2_MOUSE), contains
similarity to Pfam domain: PF00008 (EGF-like domain),
Score=107.0, E-value=1.2e-28, N=7; PF01821
(Anaphylotoxin-like domain), Score=6.5, E-value=0.3,
N=2~cDNA EST yk11b1.5 comes from thi>
emb|CAA92483.1| (Z68219) Similarity to Mouse fibrilin-2 (SW:FBL2_MOUSE), contains
similarity to Pfam domain: PF00008 (EGF-like domain),
Score=107.0, E-value=1.2e-28, N=7; PF01821
(Anaphylotoxin-like domain), Score=6.5, E-value=0.3,
N=2~cDNA EST yk11b1.5 comes from thi>
Length = 798
Score = 81.5 bits (198), Expect = 3e-14
Identities = 58/174 (33%), Positives = 78/174 (44%), Gaps = 33/174 (18%)
Query: 202 QCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEH----------------E 245
+CQ G S+ C+ P G + GP G + CE E
Sbjct: 440 ECQQGVCGSMECINLP--GTYKCKCGP---GYEFNDAKKRCEDVDECIKFAGHVCDLSAE 494
Query: 246 CVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGPQGYSCHCRLGFR 301
C+ + G C+C GF+LA+DGR CED C A CEQ+C P Y C C GF
Sbjct: 495 CINTI-GSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQKCV-NIPGSYQCICDRGFA 552
Query: 302 PAEDDPHRCVDTDECQI-AG----VCQQMCVNYVGGFECYCSEGHELEADGISC 350
D +C D DEC I AG +C C+N G + C C G++++ DG +C
Sbjct: 553 LGPDGT-KCEDIDECSIWAGSGNDLCMGGCINTKGSYLCQCPPGYKIQPDGRTC 605
Score = 69.1 bits (166), Expect = 2e-10
Identities = 52/171 (30%), Positives = 68/171 (39%), Gaps = 25/171 (14%)
Query: 202 QCQAGR--GASLLCVKQPEGGVGWSRAGPLCL-------GTGCSPDNGGCEH------EC 246
+C G GA CV P G + G LC TG D C+ EC
Sbjct: 393 ECVTGHNCGAGEECVNTP-GSFRCQQKGNLCAHGYEVNGATGFCEDVNECQQGVCGSMEC 451
Query: 247 VEEVDGHVSCRCTEGFRLAADGRSCED-----PCAQAPCEQQCEPGGPQG-YSCHCRLGF 300
+ + G C+C G+ + CED A C+ E G + C C+ GF
Sbjct: 452 IN-LPGTYKCKCGPGYEFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGF 510
Query: 301 RPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ A D RC D +EC C+Q CVN G ++C C G L DG C
Sbjct: 511 QLASDG-RRCEDVNECTTGIAACEQKCVNIPGSYQCICDRGFALGPDGTKC 560
Score = 48.4 bits (113), Expect = 3e-04
Identities = 46/172 (26%), Positives = 62/172 (35%), Gaps = 56/172 (32%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDP----CAQAPCEQQC 284
L LG C+ + CEH C + V C C GF LA DG +C D Q+PC Q
Sbjct: 153 LHLGDRCASSH--CEHLCHDRGGEKVECSCRSGFDLAPDGMACVDRNECLTRQSPCTQSE 210
Query: 285 E-PGGPQGYSCHCRLGF---------------RPAEDDPH-------------------- 308
+ GY C R+ R DDP+
Sbjct: 211 DCVNTIGGYICQRRISRLVPHRHRANRIGNAPRRMRDDPYSRAGEYREASQANTEFGCPM 270
Query: 309 -------RCVDTDEC-QIAGVC--QQMCVNYVGGFECY----CSEGHELEAD 346
CVD DEC + C Q C+N G F+C C G+ ++++
Sbjct: 271 GWLFQHGHCVDIDECATLMDDCLESQRCLNTPGSFKCIRTLSCGTGYAMDSE 322
Score = 48.0 bits (112), Expect = 4e-04
Identities = 26/66 (39%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 273 DPCAQAPCEQQCEPGGPQGYSCHCRLGFRPAEDDPHRCVDTDEC---QIAGVCQQMCVNY 329
D CA + CE C G + C CR GF A D CVD +EC Q + CVN
Sbjct: 157 DRCASSHCEHLCHDRGGEKVECSCRSGFDLAPDG-MACVDRNECLTRQSPCTQSEDCVNT 215
Query: 330 VGGFEC 335
+GG+ C
Sbjct: 216 IGGYIC 221
>gb|AAC28322.1| (AF051402) fibulin-1 isoform C precursor [Caenorhabditis elegans]
gb|AAC28323.1| (AF051403) fibulin-1 isoform C precursor [Caenorhabditis elegans]
Length = 712
Score = 81.5 bits (198), Expect = 3e-14
Identities = 58/174 (33%), Positives = 78/174 (44%), Gaps = 33/174 (18%)
Query: 202 QCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEH----------------E 245
+CQ G S+ C+ P G + GP G + CE E
Sbjct: 354 ECQQGVCGSMECINLP--GTYKCKCGP---GYEFNDAKKRCEDVDECIKFAGHVCDLSAE 408
Query: 246 CVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGPQGYSCHCRLGFR 301
C+ + G C+C GF+LA+DGR CED C A CEQ+C P Y C C GF
Sbjct: 409 CINTI-GSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQKCV-NIPGSYQCICDRGFA 466
Query: 302 PAEDDPHRCVDTDECQI-AG----VCQQMCVNYVGGFECYCSEGHELEADGISC 350
D +C D DEC I AG +C C+N G + C C G++++ DG +C
Sbjct: 467 LGPDGT-KCEDIDECSIWAGSGNDLCMGGCINTKGSYLCQCPPGYKIQPDGRTC 519
Score = 69.1 bits (166), Expect = 2e-10
Identities = 52/171 (30%), Positives = 68/171 (39%), Gaps = 25/171 (14%)
Query: 202 QCQAGR--GASLLCVKQPEGGVGWSRAGPLCL-------GTGCSPDNGGCEH------EC 246
+C G GA CV P G + G LC TG D C+ EC
Sbjct: 307 ECVTGHNCGAGEECVNTP-GSFRCQQKGNLCAHGYEVNGATGFCEDVNECQQGVCGSMEC 365
Query: 247 VEEVDGHVSCRCTEGFRLAADGRSCED-----PCAQAPCEQQCEPGGPQG-YSCHCRLGF 300
+ + G C+C G+ + CED A C+ E G + C C+ GF
Sbjct: 366 IN-LPGTYKCKCGPGYEFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGF 424
Query: 301 RPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ A D RC D +EC C+Q CVN G ++C C G L DG C
Sbjct: 425 QLASDG-RRCEDVNECTTGIAACEQKCVNIPGSYQCICDRGFALGPDGTKC 474
Score = 49.6 bits (116), Expect = 1e-04
Identities = 41/128 (32%), Positives = 52/128 (40%), Gaps = 20/128 (15%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQ 283
L LG C+ + CEH C + V C C GF LA DG +C D CA E Q
Sbjct: 153 LHLGDRCASSH--CEHLCHDRGGEKVECSCRSGFDLAPDGMACVDIDECATLMDDCLESQ 210
Query: 284 CEPGGPQGYSC----HCRLGFRPAEDDPHRCVDTDECQI----AGVCQQMCVNYVGGFEC 335
P + C C G+ + + RC D DEC + G Q C N G + C
Sbjct: 211 RCLNTPGSFKCIRTLSCGTGY-AMDSETERCRDVDECNLGSHDCGPLYQ-CRNTQGSYRC 268
Query: 336 ---YCSEG 340
C +G
Sbjct: 269 DAKKCGDG 276
>gb|AAC28321.1| (AF051401) fibulin-1 isoform D precursor [Caenorhabditis elegans]
gb|AAC28324.1| (AF051403) fibulin-1 isoform D precursor [Caenorhabditis elegans]
Length = 689
Score = 81.5 bits (198), Expect = 3e-14
Identities = 58/174 (33%), Positives = 78/174 (44%), Gaps = 33/174 (18%)
Query: 202 QCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEH----------------E 245
+CQ G S+ C+ P G + GP G + CE E
Sbjct: 354 ECQQGVCGSMECINLP--GTYKCKCGP---GYEFNDAKKRCEDVDECIKFAGHVCDLSAE 408
Query: 246 CVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGPQGYSCHCRLGFR 301
C+ + G C+C GF+LA+DGR CED C A CEQ+C P Y C C GF
Sbjct: 409 CINTI-GSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQKCV-NIPGSYQCICDRGFA 466
Query: 302 PAEDDPHRCVDTDECQI-AG----VCQQMCVNYVGGFECYCSEGHELEADGISC 350
D +C D DEC I AG +C C+N G + C C G++++ DG +C
Sbjct: 467 LGPDGT-KCEDIDECSIWAGSGNDLCMGGCINTKGSYLCQCPPGYKIQPDGRTC 519
Score = 69.1 bits (166), Expect = 2e-10
Identities = 52/171 (30%), Positives = 68/171 (39%), Gaps = 25/171 (14%)
Query: 202 QCQAGR--GASLLCVKQPEGGVGWSRAGPLCL-------GTGCSPDNGGCEH------EC 246
+C G GA CV P G + G LC TG D C+ EC
Sbjct: 307 ECVTGHNCGAGEECVNTP-GSFRCQQKGNLCAHGYEVNGATGFCEDVNECQQGVCGSMEC 365
Query: 247 VEEVDGHVSCRCTEGFRLAADGRSCED-----PCAQAPCEQQCEPGGPQG-YSCHCRLGF 300
+ + G C+C G+ + CED A C+ E G + C C+ GF
Sbjct: 366 IN-LPGTYKCKCGPGYEFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGF 424
Query: 301 RPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ A D RC D +EC C+Q CVN G ++C C G L DG C
Sbjct: 425 QLASDG-RRCEDVNECTTGIAACEQKCVNIPGSYQCICDRGFALGPDGTKC 474
Score = 49.6 bits (116), Expect = 1e-04
Identities = 41/128 (32%), Positives = 52/128 (40%), Gaps = 20/128 (15%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE--DPCAQAP---CEQQ 283
L LG C+ + CEH C + V C C GF LA DG +C D CA E Q
Sbjct: 153 LHLGDRCASSH--CEHLCHDRGGEKVECSCRSGFDLAPDGMACVDIDECATLMDDCLESQ 210
Query: 284 CEPGGPQGYSC----HCRLGFRPAEDDPHRCVDTDECQI----AGVCQQMCVNYVGGFEC 335
P + C C G+ + + RC D DEC + G Q C N G + C
Sbjct: 211 RCLNTPGSFKCIRTLSCGTGY-AMDSETERCRDVDECNLGSHDCGPLYQ-CRNTQGSYRC 268
Query: 336 ---YCSEG 340
C +G
Sbjct: 269 DAKKCGDG 276
>gb|AAC24035.1| (AF070477) fibulin-1D precursor [Caenorhabditis elegans]
Length = 589
Score = 81.5 bits (198), Expect = 3e-14
Identities = 58/174 (33%), Positives = 78/174 (44%), Gaps = 33/174 (18%)
Query: 202 QCQAGRGASLLCVKQPEGGVGWSRAGPLCLGTGCSPDNGGCEH----------------E 245
+CQ G S+ C+ P G + GP G + CE E
Sbjct: 254 ECQQGVCGSMECINLP--GTYKCKCGP---GYEFNDAKKRCEDVDECIKFAGHVCDLSAE 308
Query: 246 CVEEVDGHVSCRCTEGFRLAADGRSCED--PCAQ--APCEQQCEPGGPQGYSCHCRLGFR 301
C+ + G C+C GF+LA+DGR CED C A CEQ+C P Y C C GF
Sbjct: 309 CINTI-GSFECKCKPGFQLASDGRRCEDVNECTTGIAACEQKCV-NIPGSYQCICDRGFA 366
Query: 302 PAEDDPHRCVDTDECQI-AG----VCQQMCVNYVGGFECYCSEGHELEADGISC 350
D +C D DEC I AG +C C+N G + C C G++++ DG +C
Sbjct: 367 LGPDGT-KCEDIDECSIWAGSGNDLCMGGCINTKGSYLCQCPPGYKIQPDGRTC 419
Score = 69.1 bits (166), Expect = 2e-10
Identities = 52/171 (30%), Positives = 68/171 (39%), Gaps = 25/171 (14%)
Query: 202 QCQAGR--GASLLCVKQPEGGVGWSRAGPLCL-------GTGCSPDNGGCEH------EC 246
+C G GA CV P G + G LC TG D C+ EC
Sbjct: 207 ECVTGHNCGAGEECVNTP-GSFRCQQKGNLCAHGYEVNGATGFCEDVNECQQGVCGSMEC 265
Query: 247 VEEVDGHVSCRCTEGFRLAADGRSCED-----PCAQAPCEQQCEPGGPQG-YSCHCRLGF 300
+ + G C+C G+ + CED A C+ E G + C C+ GF
Sbjct: 266 IN-LPGTYKCKCGPGYEFNDAKKRCEDVDECIKFAGHVCDLSAECINTIGSFECKCKPGF 324
Query: 301 RPAEDDPHRCVDTDECQIA-GVCQQMCVNYVGGFECYCSEGHELEADGISC 350
+ A D RC D +EC C+Q CVN G ++C C G L DG C
Sbjct: 325 QLASDG-RRCEDVNECTTGIAACEQKCVNIPGSYQCICDRGFALGPDGTKC 374
Score = 49.2 bits (115), Expect = 2e-04
Identities = 41/129 (31%), Positives = 52/129 (39%), Gaps = 21/129 (16%)
Query: 229 LCLGTGCSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCE---DPCAQAP---CEQ 282
L LG C+ + CEH C + V C C GF LA DG +C D CA E
Sbjct: 52 LHLGDRCASSH--CEHLCHDRGGEKVECSCRSGFDLAPDGMACVDHIDECATLMDDCLES 109
Query: 283 QCEPGGPQGYSC----HCRLGFRPAEDDPHRCVDTDECQI----AGVCQQMCVNYVGGFE 334
Q P + C C G+ + + RC D DEC + G Q C N G +
Sbjct: 110 QRCLNTPGSFKCIRTLSCGTGY-AMDSETERCRDVDECNLGSHDCGPLYQ-CRNTQGSYR 167
Query: 335 C---YCSEG 340
C C +G
Sbjct: 168 CDAKKCGDG 176
>ref|NP_006320.1| fibulin 5; urine p50 protein; developmental arteries and neural
crest epidermal growth factor-like [Homo sapiens]
gb|AAC62107.1| (AF093118) UP50 [Homo sapiens]
Length = 448
Score = 81.1 bits (197), Expect = 4e-14
Identities = 45/119 (37%), Positives = 56/119 (46%), Gaps = 5/119 (4%)
Query: 235 CSPDNGGCEHE--CVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGY 292
C+ D+ C C+ G+ +C CT+G+ L D C C+Q C P Y
Sbjct: 131 CATDSHQCNPTQICINMKGGY-TCSCTDGYWLLEGQCLDIDECRYGYCQQLCA-NVPGSY 188
Query: 293 SCHCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECYCSEGHELEADGISCS 351
SC C GF ED C D +EC C Q CVN G F C C G+ELE DG+ CS
Sbjct: 189 SCTCNPGFTLNEDG-RSCQDVNECATENPCVQTCVNTYGSFICRCDPGYELEEDGVHCS 246
Score = 77.3 bits (187), Expect = 6e-13
Identities = 47/115 (40%), Positives = 56/115 (47%), Gaps = 7/115 (6%)
Query: 240 GGCEHECVEEVDGHVSCRCTEGFRLAADGRSCED--PCA-QAPCEQQCEPGGPQGYSCHC 296
G C+ C V G SC C GF L DGRSC+D CA + PC Q C + C C
Sbjct: 175 GYCQQLCAN-VPGSYSCTCNPGFTLNEDGRSCQDVNECATENPCVQTCV-NTYGSFICRC 232
Query: 297 RLGFRPAEDDPHRCVDTDECQIAG-VCQQMCVNYVGGFECYCSEGHELEADGISC 350
G+ ED H C D DEC + +CQ CVN G + C C G+ L D SC
Sbjct: 233 DPGYELEEDGVH-CSDMDECSFSEFLCQHECVNQPGTYFCSCPPGYILLDDNRSC 286
Score = 43.0 bits (99), Expect = 0.013
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 5/51 (9%)
Query: 296 CRLGFRPAEDDPHRCVDTDECQI-AGVCQ--QMCVNYVGGFECYCSEGHEL 343
CR G++ D+ ++CVD DEC + C Q+C+N GG+ C C++G+ L
Sbjct: 113 CRFGYQM--DESNQCVDVDECATDSHQCNPTQICINMKGGYTCSCTDGYWL 161
Score = 39.1 bits (89), Expect = 0.19
Identities = 34/129 (26%), Positives = 47/129 (36%), Gaps = 41/129 (31%)
Query: 235 CSPDNGGCEHECVEEVDGHVSCRCTEGFRLAADGRSCEDPCAQAPCEQQCEPGGPQGYSC 294
CS C+HECV + G C C G+ L D RSC+D +CE + ++C
Sbjct: 251 CSFSEFLCQHECVNQ-PGTYFCSCPPGYILLDDNRSCQD-------INECE---HRNHTC 299
Query: 295 HCRLGFRPAEDDPHRCVDTDECQIAGVCQQMCVNYVGGFECY----CSEGHELEADGISC 350
+ QQ C N GGF+C C E + +D
Sbjct: 300 N--------------------------LQQTCYNLQGGFKCIDPIRCEEPYLRISDNRCM 333
Query: 351 SPAGAMGAQ 359
PA G +
Sbjct: 334 CPAENPGCR 342
Database: nr
Number of letters in database: 182,691,300
Number of sequences in database: 580,189
Lambda K H
0.318 0.136 0.453
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 300805422
Number of Sequences: 580189
Number of extensions: 13751844
Number of successful extensions: 57643
Number of sequences better than 10.0: 1771
Number of HSP's better than 10.0 without gapping: 390
Number of HSP's successfully gapped in prelim test: 1423
Number of HSP's that attempted gapping in prelim test: 43926
Number of HSP's gapped (non-prelim): 7826
length of query: 757
length of database: 182,691,300
effective HSP length: 51
effective length of query: 706
effective length of database: 153,101,661
effective search space: 108089772666
effective search space used: 108089772666
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.7 bits)
S2: 75 (33.6 bits)
