ID   GBT2_BOVIN     STANDARD;      PRT;   353 AA.
AC   P04696;
DT   13-AUG-1987 (Rel. 05, Created)
DT   01-OCT-1994 (Rel. 30, Last sequence update)
DT   01-OCT-1996 (Rel. 34, Last annotation update)
DE   GUANINE NUCLEOTIDE-BINDING PROTEIN G(T), ALPHA-2 SUBUNIT (TRANSDUCIN
DE   ALPHA-2 CHAIN).
GN   GNAT2.
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Cetartiodactyla; Ruminantia; Pecora; Bovoidea;
OC   Bovidae; Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=85142187; PubMed=3856323;
RA   Lochrie M.A., Hurley J.B., Simon M.I.;
RT   "Sequence of the alpha subunit of photoreceptor G protein: homologies
RT   between transducin, ras, and elongation factors.";
RL   Science 228:96-99(1985).
RN   [2]
RP   IDENTIFICATION OF TOXIN-CATALYZED ADP-RIBOSYLATION SITE.
RX   MEDLINE=84212501; PubMed=6586721;
RA   Navon S., Fung B.K.-K.;
RT   "Characterization of transducin from bovine retinal rod outer
RT   segments. Mechanism and effects of cholera toxin-catalyzed ADP-
RT   ribosylation.";
RL   J. Biol. Chem. 259:6686-6693(1984).
CC   -!- FUNCTION: GUANINE NUCLEOTIDE-BINDING PROTEINS (G PROTEINS) ARE
CC       INVOLVED AS MODULATORS OR TRANSDUCERS IN VARIOUS TRANSMEMBRANE
CC       SIGNALING SYSTEMS.
CC   -!- FUNCTION: TRANSDUCIN IS AN AMPLIFIER AND ONE OF THE TRANSDUCERS OF
CC       A VISUAL IMPULSE THAT PERFORMS THE COUPLING BETWEEN RHODOPSIN AND
CC       CGMP-PHOSPHODIESTERASE.
CC   -!- SUBUNIT: G PROTEINS ARE COMPOSED OF 3 UNITS (ALPHA, BETA & GAMMA).
CC       THE ALPHA CHAIN CONTAINS THE GUANINE NUCLEOTIDE BINDING SITE.
CC   -!- TISSUE SPECIFICITY: OUTER SEGMENTS.
CC   -!- SIMILARITY: BELONGS TO THE G-ALPHA FAMILY. SUBFAMILY 1
CC       (G(I/O/T/Z)).
CC   --------------------------------------------------------------------------
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DR   EMBL; M11116; AAA30790.1; -.
DR   PIR; A94279; RGBOT2.
DR   HSSP; P04896; 1AZT.
DR   INTERPRO; IPR001019; -.
DR   INTERPRO; IPR001408; -.
DR   PFAM; PF00503; G-alpha; 1.
DR   PRINTS; PR00318; GPROTEINA.
DR   PRINTS; PR00441; GPROTEINAI.
KW   GTP-binding; Transducer; Vision; Multigene family; ADP-ribosylation;
KW   Myristate.
FT   INIT_MET      0      0       BY SIMILARITY.
FT   LIPID         1      1       MYRISTATE (BY SIMILARITY).
FT   NP_BIND      39     46       GTP (BY SIMILARITY).
FT   NP_BIND     199    202       GTP (BY SIMILARITY).
FT   NP_BIND     268    271       GTP (BY SIMILARITY).
FT   MOD_RES     177    177       ADP-RIBOSYL[1] (BY ACTION OF CTX).
FT   MOD_RES     350    350       ADP-RIBOSYL[1] (BY ACTION OF IAP).
SQ   SEQUENCE   353 AA;  40012 MW;  C5CD424F69D582BD CRC64;
     GSGASAEDKE LAKRSKELEK KLQEDADKEA KTVKLLLLGA GESGKSTIVK QMKIIHQDGY
     SPEECLEYKA IIYGNVLQSI LAIIRAMPTL GIDYAEVSCV DNGRQLNNLA DSIEEGTMPP
     ELVEVIRKLW KDGGVQACFD RAAEYQLNDS ASYYLNQLDR ITAPDYLPNE QDVLRSRVKT
     TGIIETKFSV KDLNFRMFDV GGQRSERKKW IHCFEGVTCI IFCAALSAYD MVLVEDDEVN
     RMHESLHLFN SICNHKFFAA TSIVLFLNKK DLFEEKIKKV HLSICFPEYD GNNSYEDAGN
     YIKSQFLDLN MRKDVKEIYS HMTCATDTQN VKFVFDAVTD IIIKENLKDC GLF
//