ID   GBAZ_RAT       STANDARD;      PRT;   354 AA.
AC   P19627;
DT   01-FEB-1991 (Rel. 17, Created)
DT   01-OCT-2000 (Rel. 40, Last sequence update)
DT   01-OCT-2000 (Rel. 40, Last annotation update)
DE   GUANINE NUCLEOTIDE-BINDING PROTEIN G(Z), ALPHA SUBUNIT (G(X) ALPHA
DE   CHAIN).
GN   GNAZ.
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Rodentia; Sciurognathi; Muridae; Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=88289726; PubMed=2456569;
RA   Matsuoka M., Itoh H., Kozasa T., Kaziro Y.;
RT   "Sequence analysis of cDNA and genomic DNA for a putative pertussis
RT   toxin-insensitive guanine nucleotide-binding regulatory protein alpha
RT   subunit.";
RL   Proc. Natl. Acad. Sci. U.S.A. 85:5384-5388(1988).
CC   -!- FUNCTION: GUANINE NUCLEOTIDE-BINDING PROTEINS (G PROTEINS) ARE
CC       INVOLVED AS MODULATORS OR TRANSDUCERS IN VARIOUS TRANSMEMBRANE
CC       SIGNALING SYSTEMS.
CC   -!- SUBUNIT: G PROTEINS ARE COMPOSED OF 3 UNITS (ALPHA, BETA & GAMMA).
CC       THE ALPHA CHAIN CONTAINS THE GUANINE NUCLEOTIDE BINDING SITE.
CC   -!- SUBCELLULAR LOCATION: MEMBRANE-BOUND.
CC   -!- SIMILARITY: BELONGS TO THE G-ALPHA FAMILY. SUBFAMILY 1
CC       (G(I/O/T/Z)).
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DR   EMBL; J03773; AAA41304.1; -.
DR   PIR; A31316; RGRTGX.
DR   HSSP; P10824; 1AS3.
DR   INTERPRO; IPR001019; -.
DR   INTERPRO; IPR001408; -.
DR   PFAM; PF00503; G-alpha; 1.
DR   PRINTS; PR00318; GPROTEINA.
DR   PRINTS; PR00441; GPROTEINAI.
KW   GTP-binding; Transducer; ADP-ribosylation; Multigene family;
KW   Lipoprotein; Palmitate; Myristate; Membrane.
FT   INIT_MET      0      0       PROBABLE.
FT   LIPID         1      1       MYRISTATE (BY SIMILARITY).
FT   LIPID         2      2       PALMITATE (BY SIMILARITY).
FT   NP_BIND      39     46       GTP (BY SIMILARITY).
FT   NP_BIND     200    203       GTP (BY SIMILARITY).
FT   NP_BIND     269    272       GTP (BY SIMILARITY).
FT   MOD_RES     178    178       ADP-RIBOSYL[1] (BY ACTION OF CTX).
SQ   SEQUENCE   354 AA;  40748 MW;  DC2D537FC7103411 CRC64;
     GCRQSSEEKE AARRSRRIDR HLRSESQRQR REIKLLLLGT SNSGKSTIVK QMKIIHSGGF
     NLEACKEYKP LIIYNAIDSL TRIIRALAAL KIDFHNPDRA YDAVQLFALT GPAESKGEIT
     PELLGVMRRL WADPGAQACF GRSSEYHLED NAAYYLNDLE RIAAPDYIPT VEDILRSRDM
     TTGIVENKFT FKELTFKMVD VGGQRSERKK WIHCFEGVTA IIFCVELSGY DLKLYEDNQT
     SRMAESLRLF DSICNNNWFI NTSLILFLNK KDLLSEKIRR IPLSVCFPEY KGQNTYEEAA
     VYIQRQFEDL NRNKETKEIY SHFTCATDTS NIQFVFDAVT DVIIQNNLKY IGLC
//