ID   GAG_HV1Z2      STANDARD;      PRT;   500 AA.
AC   P12495;
DT   01-OCT-1989 (Rel. 12, Created)
DT   01-FEB-1994 (Rel. 28, Last sequence update)
DT   15-JUL-1998 (Rel. 36, Last annotation update)
DE   GAG POLYPROTEIN [CONTAINS: CORE PROTEINS P17, P24, P2, P7, P1, P6].
GN   GAG.
OS   Human immunodeficiency virus type 1 (Z2/CDC-Z34 isolate) (HIV-1).
OC   Viruses; Retroid viruses; Retroviridae; Lentivirus.
OX   NCBI_TaxID=11683;
RN   [1]
RP   SEQUENCE FROM N.A.
RA   Theodore T., Buckler-White A.;
RL   Submitted (NOV-1988) to the HIV data bank.
CC   -!- FUNCTION: PERFORMS HIGHLY COMPLEX ORCHESTRATED TASKS DURING THE
CC       ASSEMBLY, BUDDING, MATURATION, AND INFECTION STAGES OF THE VIRAL
CC       REPLICATION CYCLE. DURING VIRAL ASSEMBLY, THE PROTEINS FORM
CC       MEMBRANE ASSOCIATIONS AND SELF-ASSOCIATIONS THAT ULTIMATELY
CC       RESULT IN BUDDING OF AN IMMATURE VIRION FROM THE INFECTED CELL.
CC       GAG PRECURSORS ALSO FUNCTION DURING VIRAL ASSEMBLY TO SELECTIVELY
CC       BIND AND PACKAGE TWO PLUS STRANDS OF GENOMIC RNA.
CC   -!- PTM: THE P24 PROTEIN IS PHOSPHORYLATED.
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DR   EMBL; M22639; AAA45365.1; -.
DR   HSSP; P05888; 1AAF.
DR   HIV; M22639; GAG$Z2Z6.
DR   INTERPRO; IPR000071; -.
DR   INTERPRO; IPR000721; -.
DR   INTERPRO; IPR001878; -.
DR   PFAM; PF00540; gag_p17; 1.
DR   PFAM; PF00607; gag_p24; 1.
DR   PFAM; PF00098; zf-CCHC; 2.
DR   PRINTS; PR00234; HIV1MATRIX.
DR   PRINTS; PR00939; C2HCZNFINGER.
KW   AIDS; Core protein; Polyprotein; Myristate; Phosphorylation;
KW   Zinc-finger.
FT   INIT_MET      0      0       BY SIMILARITY.
FT   CHAIN         1    132       CORE PROTEIN P17 (MATRIX PROTEIN).
FT   CHAIN       133    363       CORE PROTEIN P24 (CORE ANTIGEN).
FT   CHAIN       364    378       CORE PROTEIN P2.
FT   CHAIN       379    433       CORE PROTEIN P7 (NUCLEOCAPSID PROTEIN).
FT   CHAIN       434    449       CORE PROTEIN P1.
FT   CHAIN       450    500       CORE PROTEIN P6.
FT   LIPID         1      1       MYRISTATE (BY SIMILARITY).
FT   ZN_FING     393    406       C2HC-TYPE.
SQ   SEQUENCE   500 AA;  55546 MW;  B27C2609A992FB2A CRC64;
     GARASVLSGG KLDAWEKIRL RPGGKKKYRL KHLVWASREL ERFALNPGLL ETSDGCKQII
     GQLQPAIRTG SEELRSLFNT VATLYCVHER IEVKDTKEAL EKMEEEQNKS KNKKAQQAAA
     DAGNNSQVSQ NYPIVQNLQG QMVHQAISPR TLNAWVKVIE EKAFSPEVIP MFSALSEGAT
     PQDLNTMLNT VGGHQAAMQM LKETINEEAA EWDRLHPVHA GPIAPGQMRE PRGSDIAGTT
     STLQEQIAWM TSNPPIPVGE IYKRWIILGL NKIVRMYSPV SILDIRQGPK EPFRDYVDRF
     YKTLRAEQAS QEVKGWMTET LLVQNANPDC KTILKALGPQ ATLEEMMTAC QGVGGPSHKA
     RVLAEAMSQA TNSAAAVMMQ RGNFKGPRKT IKCFNCGKEG HIAKNCRAPR RKGCWKCGKE
     GHQLKDCTER QANFLGKIWP SHKGRPGNFL QSRPEPTAPP AESFGFGEEI TPSQKQEQKD
     KELYPSTALK SLFGNDPLLQ
//