ID   GAG_HV1OY      STANDARD;      PRT;   498 AA.
AC   P20889;
DT   01-FEB-1991 (Rel. 17, Created)
DT   01-FEB-1994 (Rel. 28, Last sequence update)
DT   15-JUL-1998 (Rel. 36, Last annotation update)
DE   GAG POLYPROTEIN [CONTAINS: CORE PROTEINS P17, P24, P2, P7, P1, P6].
GN   GAG.
OS   Human immunodeficiency virus type 1 (OYI isolate) (HIV-1).
OC   Viruses; Retroid viruses; Retroviridae; Lentivirus.
OX   NCBI_TaxID=11699;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=90148544; PubMed=2559749;
RA   Huet T., Dazza M.C., Brun-Vezinet F., Roelants G.E., Wain-Hobson S.;
RT   "A highly defective HIV-1 strain isolated from a healthy Gabonese
RT   individual presenting an atypical western blot.";
RL   AIDS 3:707-715(1989).
CC   -!- FUNCTION: PERFORMS HIGHLY COMPLEX ORCHESTRATED TASKS DURING THE
CC       ASSEMBLY, BUDDING, MATURATION, AND INFECTION STAGES OF THE VIRAL
CC       REPLICATION CYCLE. DURING VIRAL ASSEMBLY, THE PROTEINS FORM
CC       MEMBRANE ASSOCIATIONS AND SELF-ASSOCIATIONS THAT ULTIMATELY
CC       RESULT IN BUDDING OF AN IMMATURE VIRION FROM THE INFECTED CELL.
CC       GAG PRECURSORS ALSO FUNCTION DURING VIRAL ASSEMBLY TO SELECTIVELY
CC       BIND AND PACKAGE TWO PLUS STRANDS OF GENOMIC RNA.
CC   -!- PTM: THE P24 PROTEIN IS PHOSPHORYLATED.
CC   -!- MISCELLANEOUS: THE OYI ISOLATE WAS TAKEN FROM THE BLOOD OF A
CC       HEALTHY GABONESE INDIVIDUAL.
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DR   EMBL; M26727; AAA83391.1; -.
DR   HSSP; P05888; 1AAF.
DR   HIV; M26727; GAG$OYI.
DR   INTERPRO; IPR000071; -.
DR   INTERPRO; IPR000721; -.
DR   INTERPRO; IPR001878; -.
DR   PFAM; PF00540; gag_p17; 1.
DR   PFAM; PF00607; gag_p24; 1.
DR   PFAM; PF00098; zf-CCHC; 2.
DR   PRINTS; PR00234; HIV1MATRIX.
DR   PRINTS; PR00939; C2HCZNFINGER.
KW   AIDS; Core protein; Polyprotein; Myristate; Phosphorylation;
KW   Zinc-finger.
FT   INIT_MET      0      0       BY SIMILARITY.
FT   CHAIN         1    131       CORE PROTEIN P17 (MATRIX PROTEIN).
FT   CHAIN       132    362       CORE PROTEIN P24 (CORE ANTIGEN).
FT   CHAIN       363    376       CORE PROTEIN P2.
FT   CHAIN       377    430       CORE PROTEIN P7 (NUCLEOCAPSID PROTEIN).
FT   CHAIN       431    446       CORE PROTEIN P1.
FT   CHAIN       447    498       CORE PROTEIN P6.
FT   LIPID         1      1       MYRISTATE (BY SIMILARITY).
FT   ZN_FING     391    404       C2HC-TYPE.
SQ   SEQUENCE   498 AA;  55451 MW;  BDFF20658DEB20B1 CRC64;
     GARASVLSGG ELDKWEKIRL RPGGKKKYQL KHIVWASREL ERFAINPGLL ETSEGCRQIL
     GQLQPSLKTG SEEIRSLYNT VATLYCVHQK IEVKDTKEAL DKIEEEQNKS KKKAQQTAAD
     TGNSSQVSQN YPIVQNLQGQ MVHQPISPRT LNAWVKVVEE KAFSPEVIPM FSALAEGATP
     QDLNTMLNTV GGHQAAMQML KETINEEAAE WDRLHPVHAG PIAPGQMREP RGSDIAGTTS
     TLQEQIGWMT NNPPIPVGEI YKRWIILGLN KIVRMYSPTS ILDIRQGPKE PFRDYVDRFY
     KTLRAEQASQ DVKNWMTETL LVQNANPDCK TILKALGPAA TLEEMMTACQ GVGGPGHKAR
     VLAEAMSQVN SVTVMMQKGN FKNQRKTVKC FNCGKEGHIA KNCRAPRKKG CWKCGREGHQ
     MKDCTERQAN FLGKIWPSHK GRPGNFLQNR PEPTAPPAES FGFGEETTTP PQKQEPIDKG
     LYPLTSLRSL FGNDPSSQ
//