ID   GAG_HV1N5      STANDARD;      PRT;   499 AA.
AC   P12493;
DT   01-OCT-1989 (Rel. 12, Created)
DT   01-FEB-1994 (Rel. 28, Last sequence update)
DT   15-JUL-1998 (Rel. 36, Last annotation update)
DE   GAG POLYPROTEIN [CONTAINS: CORE PROTEINS P17, P24, P2, P7, P1, P6].
GN   GAG.
OS   Human immunodeficiency virus type 1 (New York-5 isolate) (HIV-1).
OC   Viruses; Retroid viruses; Retroviridae; Lentivirus.
OX   NCBI_TaxID=11698;
RN   [1]
RP   SEQUENCE FROM N.A. (CLONE PNL4-3).
RA   Buckler C.E., Buckler-White A.J., Willey R.L., McCoy J.;
RL   Submitted (JUN-1988) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: PERFORMS HIGHLY COMPLEX ORCHESTRATED TASKS DURING THE
CC       ASSEMBLY, BUDDING, MATURATION, AND INFECTION STAGES OF THE VIRAL
CC       REPLICATION CYCLE. DURING VIRAL ASSEMBLY, THE PROTEINS FORM
CC       MEMBRANE ASSOCIATIONS AND SELF-ASSOCIATIONS THAT ULTIMATELY
CC       RESULT IN BUDDING OF AN IMMATURE VIRION FROM THE INFECTED CELL.
CC       GAG PRECURSORS ALSO FUNCTION DURING VIRAL ASSEMBLY TO SELECTIVELY
CC       BIND AND PACKAGE TWO PLUS STRANDS OF GENOMIC RNA.
CC   -!- PTM: THE P24 PROTEIN IS PHOSPHORYLATED.
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DR   EMBL; M19921; AAA44987.1; -.
DR   HSSP; P05888; 1AAF.
DR   HIV; M19921; GAG$NL43.
DR   INTERPRO; IPR000071; -.
DR   INTERPRO; IPR000721; -.
DR   INTERPRO; IPR001878; -.
DR   PFAM; PF00540; gag_p17; 1.
DR   PFAM; PF00607; gag_p24; 1.
DR   PFAM; PF00098; zf-CCHC; 2.
DR   PRINTS; PR00234; HIV1MATRIX.
DR   PRINTS; PR00939; C2HCZNFINGER.
KW   AIDS; Core protein; Polyprotein; Myristate; Phosphorylation;
KW   Zinc-finger.
FT   INIT_MET      0      0       BY SIMILARITY.
FT   CHAIN         1    131       CORE PROTEIN P17 (MATRIX PROTEIN).
FT   CHAIN       132    362       CORE PROTEIN P24 (CORE ANTIGEN).
FT   CHAIN       363    376       CORE PROTEIN P2.
FT   CHAIN       377    431       CORE PROTEIN P7 (NUCLEOCAPSID PROTEIN).
FT   CHAIN       432    447       CORE PROTEIN P1.
FT   CHAIN       448    499       CORE PROTEIN P6.
FT   LIPID         1      1       MYRISTATE (BY SIMILARITY).
FT   ZN_FING     391    404       C2HC-TYPE.
SQ   SEQUENCE   499 AA;  55687 MW;  C8ECC1302FE2C1E2 CRC64;
     GARASVLSGG ELDKWEKIRL RPGGKKQYKL KHIVWASREL ERFAVNPGLL ETSEGCRQIL
     GQLQPSLQTG SEELRSLYNT IAVLYCVHQR IDVKDTKEAL DKIEEEQNKS KKKAQQAAAD
     TGNNSQVSQN YPIVQNLQGQ MVHQAISPRT LNAWVKVVEE KAFSPEVIPM FSALSEGATP
     QDLNTMLNTV GGHQAAMQML KETINEEAAE WDRLHPVHAG PIAPGQMREP RGSDIAGTTS
     TLQEQIGWMT HNPPIPVGEI YKRWIILGLN KIVRMYSPTS ILDIRQGPKE PFRDYVDRFY
     KTLRAEQASQ EVKNWMTETL LVQNANPDCK TILKALGPGA TLEEMMTACQ GVGGPGHKAR
     VLAEAMSQVT NPATIMIQKG NFRNQRKTVK CFNCGKEGHI AKNCRAPRKK GCWKCGKEGH
     QMKDCTERQA NFLGKIWPSH KGRPGNFLQS RPEPTAPPEE SFRFGEETTT PSQKQEPIDK
     ELYPLASLRS LFGSDPSSQ
//