ID   GAG_HV1MA      STANDARD;      PRT;   504 AA.
AC   P04594;
DT   13-AUG-1987 (Rel. 05, Created)
DT   01-FEB-1994 (Rel. 28, Last sequence update)
DT   15-JUL-1998 (Rel. 36, Last annotation update)
DE   GAG POLYPROTEIN [CONTAINS: CORE PROTEINS P17, P24, P2, P7, P1, P6].
GN   GAG.
OS   Human immunodeficiency virus type 1 (MAL isolate) (HIV-1).
OC   Viruses; Retroid viruses; Retroviridae; Lentivirus.
OX   NCBI_TaxID=11697;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=86245056; PubMed=2424612;
RA   Alizon M., Wain-Hobson S., Montagnier L., Sonigo P.;
RT   "Genetic variability of the AIDS virus: nucleotide sequence analysis
RT   of two isolates from African patients.";
RL   Cell 46:63-74(1986).
CC   -!- FUNCTION: PERFORMS HIGHLY COMPLEX ORCHESTRATED TASKS DURING THE
CC       ASSEMBLY, BUDDING, MATURATION, AND INFECTION STAGES OF THE VIRAL
CC       REPLICATION CYCLE. DURING VIRAL ASSEMBLY, THE PROTEINS FORM
CC       MEMBRANE ASSOCIATIONS AND SELF-ASSOCIATIONS THAT ULTIMATELY
CC       RESULT IN BUDDING OF AN IMMATURE VIRION FROM THE INFECTED CELL.
CC       GAG PRECURSORS ALSO FUNCTION DURING VIRAL ASSEMBLY TO SELECTIVELY
CC       BIND AND PACKAGE TWO PLUS STRANDS OF GENOMIC RNA.
CC   -!- PTM: THE P24 PROTEIN IS PHOSPHORYLATED.
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DR   EMBL; X04415; CAA28011.1; -.
DR   EMBL; A07116; CAA00618.1; -.
DR   HSSP; P05888; 1AAF.
DR   HIV; K03456; GAG$MAL.
DR   INTERPRO; IPR000071; -.
DR   INTERPRO; IPR000721; -.
DR   INTERPRO; IPR001878; -.
DR   PFAM; PF00540; gag_p17; 1.
DR   PFAM; PF00607; gag_p24; 1.
DR   PFAM; PF00098; zf-CCHC; 2.
DR   PRINTS; PR00234; HIV1MATRIX.
DR   PRINTS; PR00939; C2HCZNFINGER.
KW   AIDS; Core protein; Polyprotein; Myristate; Phosphorylation;
KW   Zinc-finger.
FT   INIT_MET      0      0       BY SIMILARITY.
FT   CHAIN         1    137       CORE PROTEIN P17 (MATRIX PROTEIN).
FT   CHAIN       138    368       CORE PROTEIN P24 (CORE ANTIGEN).
FT   CHAIN       369    383       CORE PROTEIN P2.
FT   CHAIN       384    437       CORE PROTEIN P7 (NUCLEOCAPSID PROTEIN).
FT   CHAIN       438    453       CORE PROTEIN P1.
FT   CHAIN       454    504       CORE PROTEIN P6.
FT   LIPID         1      1       MYRISTATE (BY SIMILARITY).
FT   ZN_FING     397    410       C2HC-TYPE.
SQ   SEQUENCE   504 AA;  56001 MW;  7F96785683D3B8B3 CRC64;
     GARASVLSGG KLDAWEKIRL RPGGKKKYRL KHLVWASREL ERFALNPGLL ETGEGCQQIM
     EQLQSTLKTG SEEIKSLYNT VATLYCVHQR IDVKDTKEAL DKIEEIQNKS RQKTQQAAAA
     QQAAAATKNS SSVSQNYPIV QNAQGQMIHQ AISPRTLNAW VKVIEEKAFS PEVIPMFSAL
     SEGATPQDLN MMLNIVGGHQ AAMQMLKDTI NEEAADWDRV HPVHAGPIPP GQMREPRGSD
     IAGTTSTLQE QIGWMTSNPP IPVGDIYKRW IILGLNKIVR MYSPVSILDI RQGPKEPFRD
     YVDRFFKTLR AEQATQEVKN WMTETLLVQN ANPDCKTILK ALGPGATLEE MMTACQGVGG
     PSHKARVLAE AMSQATNSTA AIMMQRGNFK GQKRIKCFNC GKEGHLARNC RAPRKKGCWK
     CGKEGHQMKD CTERQANFLG KIWPSHKGRP GNFLQSRPEP TAPPAESFGF GEEIKPSQKQ
     EQKDKELYPL ASLKSLFGND QLSQ
//