ID   GAG_HV1EL      STANDARD;      PRT;   499 AA.
AC   P04592;
DT   13-AUG-1987 (Rel. 05, Created)
DT   01-FEB-1994 (Rel. 28, Last sequence update)
DT   15-JUL-1998 (Rel. 36, Last annotation update)
DE   GAG POLYPROTEIN [CONTAINS: CORE PROTEINS P17, P24, P2, P7, P1, P6].
GN   GAG.
OS   Human immunodeficiency virus type 1 (ELI isolate) (HIV-1).
OC   Viruses; Retroid viruses; Retroviridae; Lentivirus.
OX   NCBI_TaxID=11689;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=86245056; PubMed=2424612;
RA   Alizon M., Wain-Hobson S., Montagnier L., Sonigo P.;
RT   "Genetic variability of the AIDS virus: nucleotide sequence analysis
RT   of two isolates from African patients.";
RL   Cell 46:63-74(1986).
CC   -!- FUNCTION: PERFORMS HIGHLY COMPLEX ORCHESTRATED TASKS DURING THE
CC       ASSEMBLY, BUDDING, MATURATION, AND INFECTION STAGES OF THE VIRAL
CC       REPLICATION CYCLE. DURING VIRAL ASSEMBLY, THE PROTEINS FORM
CC       MEMBRANE ASSOCIATIONS AND SELF-ASSOCIATIONS THAT ULTIMATELY
CC       RESULT IN BUDDING OF AN IMMATURE VIRION FROM THE INFECTED CELL.
CC       GAG PRECURSORS ALSO FUNCTION DURING VIRAL ASSEMBLY TO SELECTIVELY
CC       BIND AND PACKAGE TWO PLUS STRANDS OF GENOMIC RNA.
CC   -!- PTM: THE P24 PROTEIN IS PHOSPHORYLATED.
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DR   EMBL; K03454; AAA44324.1; -.
DR   EMBL; A07108; CAA00611.1; -.
DR   HSSP; P05888; 1AAF.
DR   HIV; K03454; GAG$ELI.
DR   INTERPRO; IPR000071; -.
DR   INTERPRO; IPR000721; -.
DR   INTERPRO; IPR001878; -.
DR   PFAM; PF00540; gag_p17; 1.
DR   PFAM; PF00607; gag_p24; 1.
DR   PFAM; PF00098; zf-CCHC; 2.
DR   PRINTS; PR00234; HIV1MATRIX.
DR   PRINTS; PR00939; C2HCZNFINGER.
KW   AIDS; Core protein; Polyprotein; Myristate; Phosphorylation;
KW   Zinc-finger.
FT   INIT_MET      0      0       BY SIMILARITY.
FT   CHAIN         1    131       CORE PROTEIN P17 (MATRIX PROTEIN).
FT   CHAIN       132    362       CORE PROTEIN P24 (CORE ANTIGEN).
FT   CHAIN       363    377       CORE PROTEIN P2.
FT   CHAIN       378    431       CORE PROTEIN P7 (NUCLEOCAPSID PROTEIN).
FT   CHAIN       432    447       CORE PROTEIN P1.
FT   CHAIN       448    499       CORE PROTEIN P6.
FT   LIPID         1      1       MYRISTATE (BY SIMILARITY).
FT   ZN_FING     392    405       C2HC-TYPE.
SQ   SEQUENCE   499 AA;  55582 MW;  8A1785A59EAED08D CRC64;
     GARASVLSGG KLDKWEKIRL RPGGKKKYRL KHIVWASREL ERYALNPGLL ETSEGCKQII
     GQLQPAIQTG TEELRSLYNT VATLYCVHKG IDVKDTKEAL EKMEEEQNKS KKKAQQAAAD
     TGNNSQVSQN YPIVQNLQGQ MVHQAISPRT LNAWVKVIEE KAFSPEVIPM FSALSEGATP
     QDLNTMLNTV GGHQAAMQML KETINEEAAE WDRLHPVHAG PIAPGQMREP RGSDIAGTTS
     TLQEQIAWMT SNPPIPVGEI YKRWIIVGLN KIVRMYSPVS ILDIRQGPKE PFRDYVDRFY
     KTLRAEQASQ DVKNWMTETL LVQNANPDCK TILKALGPQA TLEEMMTACQ GVGGPSHKAR
     VLAEAMSQAT NSVTTAMMQR GNFKGPRKII KCFNCGKEGH IAKNCRAPRK KGCWRCGKEG
     HQLKDCTERQ ANFLGRIWPS HKGRPGNFLQ SRPEPTAPPA ESFGFGEEIT PSQKQEQKDK
     ELYPLTSLKS LFGNDPLSQ
//