ID   ARF_GIALA      STANDARD;      PRT;   190 AA.
AC   P26991;
DT   01-AUG-1992 (Rel. 23, Created)
DT   01-JUN-1994 (Rel. 29, Last sequence update)
DT   15-JUL-1999 (Rel. 38, Last annotation update)
DE   ADP-RIBOSYLATION FACTOR.
OS   Giardia lamblia (Giardia intestinalis).
OC   Eukaryota; Diplomonadida; Hexamitidae; Giardiinae; Giardia.
OX   NCBI_TaxID=5741;
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE=92250616; PubMed=1577802;
RA   Murtagh J.J. Jr., Mowatt M.W., Lee C.-M., Lee F.-J.S., Mishima K.,
RA   Nash T.E., Moss J., Vaughan M.;
RT   "Guanine nucleotide-binding proteins in the intestinal parasite
RT   Giardia lamblia. Isolation of a gene encoding an approximately 20-kDa
RT   ADP-ribosylation factor.";
RL   J. Biol. Chem. 267:9654-9662(1992).
CC   -!- FUNCTION: GTP-BINDING PROTEIN THAT FUNCTIONS AS AN ALLOSTERIC
CC       ACTIVATOR OF THE CHOLERA TOXIN CATALYTIC SUBUNIT, AN ADP-
CC       RIBOSYLTRANSFERASE. INVOLVED IN PROTEIN TRAFFICKING; MAY MODULATE
CC       VESICLE BUDDING AND UNCOATING WITHIN THE GOLGI APPARATUS.
CC   -!- SIMILARITY: BELONGS TO THE ARF FAMILY OF GTP-BINDING PROTEINS.
CC   --------------------------------------------------------------------------
CC   This SWISS-PROT entry is copyright. It is produced through a collaboration
CC   between  the Swiss Institute of Bioinformatics  and the  EMBL outstation -
CC   the European Bioinformatics Institute.  There are no  restrictions on  its
CC   use  by  non-profit  institutions as long  as its content  is  in  no  way
CC   modified and this statement is not removed.  Usage  by  and for commercial
CC   entities requires a license agreement (See http://www.isb-sib.ch/announce/
CC   or send an email to license@isb-sib.ch).
CC   --------------------------------------------------------------------------
DR   EMBL; M86513; -; NOT_ANNOTATED_CDS.
DR   PIR; S29008; S29008.
DR   HSSP; P32889; 1RRF.
DR   INTERPRO; IPR000251; -.
DR   PFAM; PF00025; arf; 1.
DR   PROSITE; PS01019; ARF; 1.
KW   GTP-binding; Myristate; Protein transport; Golgi stack.
FT   INIT_MET      0      0       BY SIMILARITY.
FT   LIPID         1      1       MYRISTATE (POTENTIAL).
FT   NP_BIND      23     30       GTP (BY SIMILARITY).
FT   NP_BIND      66     70       GTP (BY SIMILARITY).
FT   NP_BIND     127    130       GTP (BY SIMILARITY).
SQ   SEQUENCE   190 AA;  21634 MW;  B05549FA0DA49036 CRC64;
     GQGASKIFGK LFSKKEVRIL MVGLDAAGKT TILYKLMLGE VVTTVPTIGF NVETVEYKNI
     NFTVWDVGGQ DSIRPLWRHY YQNTDALIYV IDSADLEPKR IEDAKNELHT LLGEDELRDA
     ALLVFANKQD LPKAMSTTDL TERLGLQELK KRDWYIQPTC ARSGDGLYQG LDWLSDYIFD
     KKNKKKGKKR
//