ID   APKB_ARATH     STANDARD;      PRT;   412 AA.
AC   P46573; Q9SLH5;
DT   01-NOV-1995 (Rel. 32, Created)
DT   01-OCT-2000 (Rel. 40, Last sequence update)
DT   01-OCT-2000 (Rel. 40, Last annotation update)
DE   PROTEIN KINASE APK1B (EC 2.7.1.-).
GN   APK1B OR AT2G28930 OR T9I4.1.
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Embryophyta; Tracheophyta; Spermatophyta;
OC   Magnoliophyta; eudicotyledons; core eudicots; Rosidae; eurosids II;
OC   Brassicales; Brassicaceae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   SEQUENCE FROM N.A.
RC   STRAIN=CV. COLUMBIA;
RX   MEDLINE=20083487; PubMed=10617197;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H., Moffat K.S.,
RA   Cronin L.A., Shen M., VanAken S.E., Umayam L., Tallon L.J., Gill J.E.,
RA   Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R.,
RA   Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A.,
RA   Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis
RT   thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   SEQUENCE OF 143-346 FROM N.A.
RC   STRAIN=CV. COLUMBIA;
RX   MEDLINE=93081726; PubMed=1450380;
RA   Hirayama T., Oka A.;
RT   "Novel protein kinase of Arabidopsis thaliana (APK1) that
RT   phosphorylates tyrosine, serine and threonine.";
RL   Plant Mol. Biol. 20:653-662(1992).
CC   -!- FUNCTION: POSSIBLE BI-FUNCTIONAL KINASE. IN VITRO, IT EXHIBITS
CC       SERINE/THREONINE ACTIVITY. IN VIVO, CAN PHOSPHORYLATE TYROSINE
CC       RESIDUES OF LIMITED SUBSTRATES (BY SIMILARITY).
CC   -!- SIMILARITY: BELONGS TO THE SER/THR FAMILY OF PROTEIN KINASES.
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DR   EMBL; AC005315; AAC33221.1; -.
DR   EMBL; D10152; BAA20968.1; -.
DR   HSSP; P08631; 2HCK.
DR   INTERPRO; IPR000719; -.
DR   INTERPRO; IPR001245; -.
DR   INTERPRO; IPR002290; -.
DR   PFAM; PF00069; pkinase; 1.
DR   PRINTS; PR00109; TYRKINASE.
DR   PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR   PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
DR   PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
KW   Transferase; Serine/threonine-protein kinase; Tyrosine-protein kinase;
KW   ATP-binding; Multigene family; Myristate.
FT   LIPID         2      2       MYRISTATE (BY SIMILARITY).
FT   DOMAIN       69    356       PROTEIN KINASE.
FT   NP_BIND      75     83       ATP (BY SIMILARITY).
FT   BINDING     107    107       ATP (BY SIMILARITY).
FT   ACT_SITE    204    204       BY SIMILARITY.
SQ   SEQUENCE   412 AA;  45746 MW;  EB1CA0B1A626A5DA CRC64;
     MGICLSAQIK AVSPGASPKY MSSEANDSLG SKSSSVSIRT NPRTEGEILQ SPNLKSFTFA
     ELKAATRNFR PDSVLGEGGF GSVFKGWIDE QTLTASKPGT GVVIAVKKLN QDGWQGHQEW
     LAEVNYLGQF SHPNLVKLIG YCLEDEHRLL VYEFMPRGSL ENHLFRRGSY FQPLSWTLRL
     KVALGAAKGL AFLHNAETSV IYRDFKTSNI LLDSEYNAKL SDFGLAKDGP TGDKSHVSTR
     IMGTYGYAAP EYLATGHLTT KSDVYSYGVV LLEVLSGRRA VDKNRPPGEQ KLVEWARPLL
     ANKRKLFRVI DNRLQDQYSM EEACKVATLA LRCLTFEIKL RPNMNEVVSH LEHIQTLNEA
     GGRNIDMVQR RMRRRSDSVA INQKPNAGFA RQTAVGVIAT AYPRPSDSPL FV
//