ID   VSA8_TRYBB     STANDARD;      PRT;   115 AA.
AC   P06017;
DT   13-AUG-1987 (REL. 05, CREATED)
DT   13-AUG-1987 (REL. 05, LAST SEQUENCE UPDATE)
DT   01-MAY-1992 (REL. 22, LAST ANNOTATION UPDATE)
DE   VARIANT SURFACE GLYCOPROTEIN ANTAT 1.8 (VSG) (FRAGMENT).
OS   TRYPANOSOMA BRUCEI BRUCEI.
OC   EUKARYOTA; PROTOZOA; SARCOMASTIGOPHORA; MASTIGOPHORA; KINETOPLASTIDA;
OC   TRYPANOSOMATIDAE.
RN   [1]
RP   SEQUENCE FROM N.A.
RX   MEDLINE; 82013622.
RA   MATTHYSSENS G., MICHIELS F., HAMERS R., PAYS E., STEINERT M.;
RL   NATURE 293:230-233(1981).
CC   -!- FUNCTION: VSG FORMS A COAT ON THE SURFACE OF THE PARASITE. THE
CC       TYPANOSOME EVADES THE IMMUNE RESPONSE OF THE HOST BY EXPRESSING
CC       A SERIES OF ANTIGENICALLY DISTINCT VSGS FROM AN ESTIMATED 1000
CC       VSG GENES.
CC   -!- SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A GPI-ANCHOR.
CC       A SOLUBLE FORM IS RELASED FROM RUPTURED CELLS BY THE ACTION OF A
CC       PI-PLC.
DR   EMBL; J01227; G162398; -.
DR   PIR; S07326; S07326.
KW   GLYCOPROTEIN; ANTIGEN; TRYPANOSOMIASIS; GPI-ANCHOR; MEMBRANE.
FT   NON_TER       1      1
FT   CHAIN        <1     92       VARIANT SURFACE GLYCOPROTEIN ANTAT 1.8.
FT   PROPEP       93    115       HYDROPHOBIC, REMOVED DURING MATURATION.
FT   LIPID        92     92       GPI-ANCHOR.
SQ   SEQUENCE   115 AA;  12530 MW;  81E5858D CRC32;
     DQKGKSPESE CNKISEEPKC NEDKICSWHK EVKAGEKHCK FNSTKAKEKG VAVTQTQTAG
     GTEATTDKCK GKLEDTCKKE SNCKWEGETC KDSSILVNKQ LALSVVSAAF AALLF
//