ID   CD59_SAISC     STANDARD;      PRT;   131 AA.
AC   P47777;
DT   01-FEB-1996 (REL. 33, CREATED)
DT   01-FEB-1996 (REL. 33, LAST SEQUENCE UPDATE)
DT   15-JUL-1998 (REL. 36, LAST ANNOTATION UPDATE)
DE   CD59 GLYCOPROTEIN PRECURSOR (MEMBRANE ATTACK COMPLEX INHIBITION
DE   FACTOR) (MACIF) (MAC-INHIBITORY PROTEIN) (MAC-IP) (PROTECTIN).
GN   CD59.
OS   SAIMIRI SCIUREUS (COMMON SQUIRREL MONKEY).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA;
OC   EUTHERIA; PRIMATES.
RN   [1]
RP   SEQUENCE FROM N.A.
RC   TISSUE=LUNG;
RX   MEDLINE; 94118421.
RA   ROTHER R.P., ROLLINS S.A., FODOR W.L., ALBRECHT J.-C., SETTER E.,
RA   FLECKENSTEIN B., SQUINTO S.P.;
RL   J. VIROL. 68:730-737(1994).
CC   -!- FUNCTION: POTENT INHIBITOR OF THE COMPLEMENT MEMBRANE ATTACK
CC       COMPLEX (MAC) ACTION. ACTS AT OR AFTER THE C5B-8 STAGE OF MAC
CC       ASSEMBLY.
CC   -!- SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A GPI-ANCHOR
CC       (BY SIMILARITY).
CC   -!- SIMILARITY: CONTAINS 1 UPAR/LY6 DOMAIN.
DR   EMBL; L22859; G404797; -.
DR   PROSITE; PS00983; LY6_UPAR; FALSE_NEG.
KW   ANTIGEN; GLYCOPROTEIN; GPI-ANCHOR; SIGNAL.
FT   SIGNAL        1     25       BY SIMILARITY.
FT   CHAIN        26    105       CD59 GLYCOPROTEIN.
FT   PROPEP      106    131       REMOVED IN MATURE FORM (BY SIMILARITY).
FT   LIPID       105    105       GPI-ANCHOR (BY SIMILARITY).
FT   DOMAIN       26    111       UPAR/LY6.
FT   DISULFID     28     54       BY SIMILARITY.
FT   DISULFID     31     41       BY SIMILARITY.
FT   DISULFID     47     67       BY SIMILARITY.
FT   DISULFID     73     91       BY SIMILARITY.
FT   DISULFID     92     97       BY SIMILARITY.
FT   CARBOHYD     46     46       POTENTIAL.
SQ   SEQUENCE   131 AA;  14355 MW;  09EDCB2E CRC32;
     MGIQGGSVLF GLLLVLAVFC HSGNSLQCYS CPLPTMESME CTASTNCTSN LDSCLIAKAG
     SGVYYRCWKF DDCSFKRISN QLSETQLKYH CCKKNLCNVK EVLENGGTTL SKKTILLLVT
     PFLAAAWSRH P
//