ID   5NTD_DISOM     STANDARD;      PRT;   577 AA.
AC   P29240;
DT   01-DEC-1992 (REL. 24, CREATED)
DT   01-DEC-1992 (REL. 24, LAST SEQUENCE UPDATE)
DT   15-JUL-1998 (REL. 36, LAST ANNOTATION UPDATE)
DE   5'-NUCLEOTIDASE PRECURSOR (EC 3.1.3.5) (ECTO-NUCLEOTIDASE).
OS   DISCOPYGE OMMATA (ELECTRIC RAY).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; PISCES; GNATHOSTOMATA;
OC   CHONDRICHTHYES.
RN   [1]
RP   SEQUENCE FROM N.A.
RC   TISSUE=ELECTRIC LOBE;
RX   MEDLINE; 92111535.
RA   VOLKNANDT W., VOGEL M., PEVSNER J., MISUMI Y., IKEHARA Y.,
RA   ZIMMERMANN H.;
RL   EUR. J. BIOCHEM. 202:855-861(1991).
CC   -!- FUNCTION: HYDROLYZES EXTRACELLULAR NUCLEOTIDES INTO MEMBRANE
CC       PERMEABLE NUCLEOSIDES.
CC   -!- CATALYTIC ACTIVITY: A 5'-RIBONUCLEOTIDE + H(2)O = A
CC       RIBONUCLEOSIDE + ORTHOPHOSPHATE.
CC   -!- COFACTOR: ZINC.
CC   -!- SUBUNIT: HOMODIMER, LINKED BY DISULFIDE BOND(S) (BY SIMILARITY).
CC   -!- SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A GPI-ANCHOR.
CC   -!- SIMILARITY: BELONGS TO THE 5'-NUCLEOTIDASE FAMILY.
DR   EMBL; X62278; G62772; -.
DR   PIR; S17356; S17356.
DR   PIR; S19564; S19564.
DR   PROSITE; PS00785; 5_NUCLEOTIDASE_1; 1.
DR   PROSITE; PS00786; 5_NUCLEOTIDASE_2; 1.
KW   HYDROLASE; SIGNAL; GPI-ANCHOR; GLYCOPROTEIN; ZINC.
FT   SIGNAL        1     30
FT   CHAIN        31    552       5'-NUCLEOTIDASE.
FT   PROPEP      553    577       REMOVED IN MATURE FORM.
FT   LIPID       552    552       GPI-ANCHOR (BY SIMILARITY).
FT   CARBOHYD    135    135       POTENTIAL.
FT   CARBOHYD    311    311       POTENTIAL.
FT   CARBOHYD    347    347       POTENTIAL.
FT   CARBOHYD    403    403       POTENTIAL.
SQ   SEQUENCE   577 AA;  63613 MW;  4C89B5B3 CRC32;
     MPRVPSASAT GSSALLSLLC AFSLGRAAPF QLTILHTNDV HARVEETNQD SGKCFTQSFA
     GVARRWTKIE ELRARDKNVL LLDAGDQYQG TIWFNYYKGA EAAHFIEAVG YNAMALGNHE
     FDNGAEGLLD PFLLNVSFPV LSANLEQGED QVPSLIGYYK PSTVLDVNGE KIGVVGYTSK
     ETPTLSSPGP HLIFKDEIQA VQHEVDILVS QGIDKIIALG HSGFETDKLI AQKVRGVDVV
     VGGHSNTFLY TGKAPSNDVP VGPYPFLVNS DDQRTIPVVQ AYAYGKYLGY LKLTFDKGEV
     IKREGNPILL NSSIIQDPVL LAEVNKWKES LANFGKEVIG RTVVYLNGTT EECRNRECNM
     GNLICDAMIQ QNIRNPDEKF WNHVSICIFQ GGGIRAPINE QNNGTIQVDS LLAVLPFGST
     IDLLEVYGST LRAAFDHSVR RYGQNTGEFL QVSGIQVQFN LKRPPGSRVV KIDVLCADCR
     VPHYQPLLDN KIYKIVTNSY IAEGGDGFTM LKNERLRYDT GSTDISVVSS YIKQMKVVYP
     AVEGRILFVE NSATLPIINL KIGLSLFAFL TWFLHCS
//