ID   5NTD_BOVIN     STANDARD;      PRT;   574 AA.
AC   Q05927;
DT   01-FEB-1994 (REL. 28, CREATED)
DT   01-FEB-1994 (REL. 28, LAST SEQUENCE UPDATE)
DT   15-JUL-1998 (REL. 36, LAST ANNOTATION UPDATE)
DE   5'-NUCLEOTIDASE PRECURSOR (EC 3.1.3.5) (ECTO-NUCLEOTIDASE) (5'-NT)
DE   (CD73 ANTIGEN).
GN   NT5.
OS   BOS TAURUS (BOVINE).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA;
OC   EUTHERIA; ARTIODACTYLA.
RN   [1]
RP   SEQUENCE FROM N.A., AND PARTIAL SEQUENCE.
RC   TISSUE=LIVER;
RX   MEDLINE; 93340109.
RA   SUZUKI K., FURUKAWA Y., TAMURA H., EJIRI N., SUEMATSU H.,
RA   TAGUCHI R., NAKAMURA S., SUZUKI Y., IKEZAWA H.;
RL   J. BIOCHEM. 113:607-613(1993).
CC   -!- FUNCTION: HYDROLYZES EXTRACELLULAR NUCLEOTIDES INTO MEMBRANE
CC       PERMEABLE NUCLEOSIDES.
CC   -!- CATALYTIC ACTIVITY: A 5'-RIBONUCLEOTIDE + H(2)O = A
CC       RIBONUCLEOSIDE + ORTHOPHOSPHATE.
CC   -!- COFACTOR: ZINC.
CC   -!- SUBUNIT: HOMODIMER, LINKED BY DISULFIDE BOND(S).
CC   -!- SUBCELLULAR LOCATION: ATTACHED TO THE MEMBRANE BY A GPI-ANCHOR.
CC   -!- SIMILARITY: BELONGS TO THE 5'-NUCLEOTIDASE FAMILY.
DR   EMBL; D14541; G285642; -.
DR   EMBL; S64302; G404502; -.
DR   PIR; JX0269; JX0269.
DR   PIR; JQ1980; JQ1980.
DR   PROSITE; PS00785; 5_NUCLEOTIDASE_1; 1.
DR   PROSITE; PS00786; 5_NUCLEOTIDASE_2; 1.
KW   HYDROLASE; SIGNAL; GPI-ANCHOR; GLYCOPROTEIN; ZINC.
FT   SIGNAL        1     26
FT   CHAIN        27    549       5'-NUCLEOTIDASE.
FT   PROPEP      550    574       REMOVED IN MATURE FORM (BY SIMILARITY).
FT   LIPID       549    549       GPI-ANCHOR.
FT   CARBOHYD     53     53       POTENTIAL.
FT   CARBOHYD    311    311       POTENTIAL.
FT   CARBOHYD    333    333       POTENTIAL.
FT   CARBOHYD    403    403       POTENTIAL.
SQ   SEQUENCE   574 AA;  63085 MW;  A37A15C1 CRC32;
     MNPGAARTPA LRILPLGALL WPAARPWELT ILHTNDVHSR LEQTSEDSSK CVNASRCVGG
     VARLATKVHQ IRRAEPHVLL LDAGDQYQGT IWFTVYKGTE VAHFMNALGY ESMALGNHEF
     DNGVEGLIDP LLKEVNFPIL SANIKAKGPL ASKISGLYSP YKILTVGDEV VGIVGYTSKE
     TPFLSNPGTN LVFEDEITAL QPEVDKLKTL NVNKIIALGH SGFEVDKLIA QKVKGVDVVV
     GGHSNTFLYT GNPPSKEVPA GQYPFIVTSD DGRKVPVVQA YAFGKYLGYL KVEFDEKGNV
     VTSHGNPILL NSSIPEDPNI KADINKWRVK LDNYSTQELG KTIVYLDGTA QSCRFRECNM
     GNLICDAMIN NNLRHPDEMS WNHVSMCILN GGGIRSPIDE RNNGTITWEN LAAVLPFGGT
     FDLVQLKGST LKKAFDDTVH RYGQRTGEFL QVGGIHVVYD ISRNPGDRVV KLEVLCTQCR
     VPSYEPLRMD KVYKVILPSF LVSGGDGFQM IKDEKIKHDS GDQDINVVSG YISKMKVLYP
     AVEGRIQFSA GSHCCGSFSL IFLSVLAVII ILYQ
//