
| YJR004C | 3.17 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 9.35 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.13 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.56 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.20 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.61 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -2.35 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.18 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.14 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YNR044W | 8.21 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.82 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.86 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.97 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.27 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.49 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YKL096W | 14.35 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.41 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.06 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YKL097W-A | 17.62 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.86 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.88 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YAL063C | 10.37 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.34 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.87 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.09 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YAR050W | 10.37 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.34 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.87 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.09 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YHR211W | 10.37 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.34 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.87 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -5.09 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YKR102W | -14.93 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 6.16 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.04 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.45 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.22 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.36 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | -8.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | -12.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YBR067C | 19.62 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.05 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.13 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YER011W | 16.92 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.71 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.41 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.01 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YIL011W | 18.47 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.43 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.82 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.08 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.06 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YJR150C | 19.49 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.43 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.05 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YOR010C | 15.32 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.50 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.19 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.24 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YCR089W | 10.23 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.61 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.71 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.14 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -2.24 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.29 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR390W-A | 14.64 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.59 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.24 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.50 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.13 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.08 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YNL322C | -2.39 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.30 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.12 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -4.41 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -3.39 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.78 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.97 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YMR307W | 13.74 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.09 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -2.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.31 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.08 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YFL067W | -8.34 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 5.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.12 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.24 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.22 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | -4.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | -8.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.38 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.61 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YDR349C | -4.65 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 5.62 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | -4.00 |
| Function 3 = Sum : volume function [-1..2] | -3.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.52 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.78 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.43 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.01 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.20 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YIR039C | 11.02 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.80 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.50 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.46 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.15 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.37 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR120C | 0.65 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.90 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -4.79 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -1.53 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.70 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.21 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.02 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YDR261C | -19.63 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 3.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -2.64 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -7.66 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -6.29 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -3.11 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -2.45 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.02 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.44 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.05 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.03 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YIR019C | 10.57 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.57 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.01 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.86 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.14 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YMR008C | 9.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 12.83 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.08 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.80 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.24 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.54 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YJL078C | 12.67 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.09 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.33 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.35 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.61 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YNL327W | 16.28 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.26 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.67 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.31 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YJR151C | 16.84 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.18 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.15 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.09 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YCR061W | -61.27 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | -19.44 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.03 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.45 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.27 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.60 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.21 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -6.62 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.11 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | -12.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -4.11 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -3.44 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | -12.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YDR055W | 14.38 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.03 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.95 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.37 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.50 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YDR077W | 17.48 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.28 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.45 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.26 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.05 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YDR134C | 17.25 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.52 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.27 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YDR534C | 18.55 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.84 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.29 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YEL040W | 15.97 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.55 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.13 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.15 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YER150W | 19.01 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 20.06 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.15 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YFR054C | -30.31 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 3.21 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.10 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.01 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | -16.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -1.63 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | -12.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.93 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -2.82 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YGR189C | 12.28 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.84 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -2.50 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YJL171C | -16.54 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 0.23 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -1.14 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -1.03 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.06 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.04 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.93 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | -12.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.90 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.24 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR040C | 13.28 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.67 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.50 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.49 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.26 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.09 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR042C | 5.39 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 8.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.08 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.21 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.15 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.03 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.52 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.68 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR110C | 17.75 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.02 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.26 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YLR121C | 14.79 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.01 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.52 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YLR194C | 17.30 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 17.55 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.08 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.06 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.06 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.01 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YMR172C-A | -43.01 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | -16.00 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -2.74 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | -4.00 |
| Function 3 = Sum : volume function [-1..2] | -4.65 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -3.23 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -1.53 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -1.06 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | -8.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.26 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.03 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.52 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YMR215W | 16.14 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 16.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.19 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YNL190W | 13.41 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 14.85 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.61 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.56 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YNL300W | 14.27 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.37 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.68 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.41 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.01 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YOL011W | 12.45 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 15.86 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.42 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.09 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.07 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.34 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.20 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -1.09 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.18 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YOR009W | 16.51 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 18.83 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.32 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.03 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.01 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -1.95 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YOR146W | -37.27 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 6.07 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.21 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | -28.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.67 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | -12.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | -0.93 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -1.45 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YOR214C | 12.77 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.19 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.15 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.14 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.04 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.04 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.06 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YOR382W | 21.12 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 21.12 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | 0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

| YOR383C | 19.29 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 19.65 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | -0.05 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | 0.00 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | 0.00 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | 0.00 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.00 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | -0.31 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | 0.00 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | 0.00 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | -0.00 |

| YPL130W | 11.69 |
|---|
| Functions | Score Components |
|---|---|
| Profile Score | 13.42 |
| N-terminal unstructured region [-11..-1] |   |
| Function 0 = Combi_contents_win_penalty : contents and windows of DE in N-terminal region | 0.00 |
| Function 1 = Lower_Average : hydrophilicity of N-terminal region [-11..-1] | 0.00 |
| omega-site region [-1..2] |   |
| Function 2 = PenaltyForBadProfile : penalty for bad Omega-Site | 0.00 |
| Function 3 = Sum : volume function [-1..2] | -0.46 |
| Function 4 = Sum3 : volume function for three positions (0, 1, 2) | -0.70 |
| Function 5 = Sum2 : volume function for two positions (0, 1) | -0.27 |
| Function 21 = Sum2 : volume function for two positions (1, 2) | -0.01 |
| Function 6 = Penalty_Mobility : penalty for more than one residue out of P, T, V, I | 0.00 |
| Function 7 = C_Position : penalty, if site is outside of interval[from..to] relative to C-terminal | 0.00 |
| spacer region [3..8] |   | Function 8 = Lower_Average : hydrophilicity of spacer region [3..8] | 0.00 |
| Function 9 = Lower_Average : function for spacer volume (mean for positions 3..8) | -0.26 |
| Function 10 = Charged_AA_Penalty_Spacer : penalty for charged AA (DEKRH) in spacer (H=2/3) | 0.00 |
| Function 11 = Flexibility_Spacer : contents of PVI in spacer | 0.00 |
| tail [9..C_End] |   |
| Function 12 = PenaltyForBadProfile : penalty for bad profile in hydrophobic tail | 0.00 |
| Function 13 = Higher_Average: function for hydrophobic region [10..C_end] (for at least the par4=8 last AAs) | 0.00 |
| Function 14 = Higher_Average : function for hydrophobic tail [26..C_end](for at least the par4=8 last AAs) | -0.04 |
| Function 15 = Sliding_Window : penalty for too short even hydrophobic section | 0.00 |
| Function 16 = Post_Sliding_Window_Polar_Penalty : penalty for polar windows in the hydrophobic tail | 0.00 |
| Function 17 = Post_Sliding_Window_SGC_Penalty : penalty for too long SGC - sections (len = par4) in hydrophobic tail | 0.00 |
| Function 18 = LVI_contents : contents of Leu, Val, Ile in the hydrophobic tail | 0.00 |
| Function 19 = Combi_FWHY_contents_2win : penalty if more than 40% WHFY and 2 disconnected windows (l=4) with > 2 aromats | 0.00 |
| Function 20 = Sliding_Window : penalty for small (according to volume) windows in tail | 0.00 |

Last modified: 25th September 2003