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Functional classification of Saccharomyces cerevisiae hits

Contact:
Birgit Eisenhaber (IMP/Austria)
Georg Schneider (IMP/Austria)
Michael Wildpaner (IMP/Austria)
Frank Eisenhaber (IMP/Austria)

Summary Table:

Protein Families Number of Proteins with predicted N-terminal Signal Peptide Number of Proteins without predicted N-terminal Signal Peptide
Agglutinin-like 2 -
Other Cell Wall Proteins 11 1
Factor-Induced Gene 2 (FIG2) 1 -
Flocculins 3 -
GAS1 5 -
Lysophospholipases 3 -
Peptidases 4 -
Receptor-like 1 -
SCP-like 1 -
Seripauperin and TIP1 family 7 -
SPS2-like 2 -
Sugar Hydrolases 5 1
Transporters 1 2
Yeast PIR protein repeats 3 -
Other Functions - 6
Hypothetical Proteins/Unknown Function 10 6

Agglutinin-like

YJR004C (SAG1_YEAST Alpha-agglutinin precursor)
YNR044W

Other Cell Wall Proteins

YDR077W (cell surface glycoprotein; Sed1p)
YER150W (cell surface glycoprotein; Sed1p homolog)
YDR134C (CW12_YEAST homolog, also Flocculin)
YLR110C (CW12_YEAST, also Flocculin)
YLR390W-A (CW14_YEAST)
YDR534C (FIT1, FIT2, and FIT3 homolog)
YOR214C (Hamada et al. 1998)
YOR383C (FIT1, FIT2, and FIT3 homolog)
YNL300W (Hamada et al. 1998)
YNL327W (EGT2_YEAST homolog)
YOL155C (cell wall protein Awa1p)
without predicted N-terminal signal peptide
YOR382W (FIT1, FIT2, and FIT3 homolog)

Factor-Induced Gene 2

YCR089W (FIG2)

Flocculins (PF00624, Flocculin repeat)

YAL063C 
YAR050W
YHR211W

GAS1 (PF03198, Glycolipid anchored surface protein (GAS1))

YMR215W
YMR307W
YOL030W 
YLR343W (S>0)
YOL132W (S>0)

Lysophospholipases (PLA2_B, PF01735)

YMR006C
YMR008C
YOL011W

Peptidases

Eukaryotic aspartyl protease (PF00026)
YDR144C
YIR039C
YLR121C 
YLR120C (S>0)

Recep_L_domain (PF01030, Receptor L domain)

YDR055W

SCP (PF00188, SCP-like extracellular protein)

YJL078C

Seripauperin and TIP1 family (SRP1_TIP1, PF00660)

YBR067C
YER011W 
YIL011W 
YJR150C 
YJR151C
YOR009W
YOR010C

SPS2-like

YCL048W (SPS2-LIKE, Ecm33p homolog)
YDR522C (SPS2-LIKE, Ecm33p homolog)

Sugar Hydrolases

glycosyl hydrolases (families 16 and 76; PF00722, PF03663)
YEL040W (Glyco_hydro_16)
YGR189C (Glyco_hydro_16)
YKL046C (Glyco_hydro_76)
YMR238W (Glyco_hydro_76)
Glucoamylase
YIR019C
without predicted N-terminal signal peptide
YMR317W 

Transportes

YKL175W (PF02535, ZIP Zinc transporter)
without predicted N-terminal signal peptide
YAL022C (PF01733, Nucleoside transporter)
YNR056C (S>0) (regulator of KAPA/DAPA transport)

Yeast PIR protein repeats (PF00399, yeast_PIR)

YHR126C 
YKL096W 
YKL096W-A

Other Functions

without predicted N-terminal signal peptide
YNL111C (S>0) (PF00173, Heme/Steroid binding domain)
YGR136W (PF00018, SH3 domain)
YOR075W (t_SNARE)
YER100W (PF00179, Ubiquitin-conjugating enzyme)
YDL195W (S>0) (PF00400, WD domain, G-beta repeat)
YDR263C (S>0) (PF00752, XPG N-terminal domain)

Hypothetical Proteins/Unknown Function

YLR040C
YLR042C
YLR194C 
YMR122W-A 
YMR200W
YMR251W-A
YNL190W 
YOL052C-A 
YPL130W (SPO19)
YGR228W (S>0)
without predicted N-terminal signal peptide
YLR220W (PF01988, DUF125)
YBL091C-A
YDL039C 
YGR259C
YKL006C-A (Required for transport of proteins between an early and a later golgi compartment)
YKR033C



Last modified: 17th September 2003