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The prediction of the GAS1 mutation set

(Nuoffer C. et al, J Biol Chem. 1993 May 15;268(14):10558-63.)

Contact:
Birgit Eisenhaber (IMP/Austria)
Georg Schneider (IMP/Austria)
Michael Wildpaner (IMP/Austria)
Frank Eisenhaber (IMP/Austria)

Summary Table:

  Mutations: GPI anchored no GPI anchor total number
    51 14 65
correct predictons: 48/51 8/14 56/65 (86.2%)
wrong predictons: 3/51 6/14 9/65 (13.8%)

N   Protein Length Quality Site Score PValue Alternative Site Score PValue Experiment
1 GAS1_YEAST 559 1:P 528 13.74 1.012428e-05 2:P 529 5.90 1.522516e-04 anchored
2 GAS1_N506S 559 1:P 528 15.96 4.084720e-06 2:P 529 7.57 9.083925e-05 anchored
3 GAS1_N506G 559 1:P 528 15.60 4.743625e-06 2:P 529 6.01 1.473822e-04 anchored
4 GAS1_N506A 559 1:P 528 13.47 1.126353e-05 2:P 529 5.98 1.486215e-04 anchored
5 GAS1_N506D 559 1:P 528 9.40 4.972283e-05 2:P 529 4.49 2.306970e-04 anchored
6 GAS1_N506C 559 1:P 528 10.36 3.574069e-05 -     anchored
7 GAS1_N506E 559 1:P 529 5.70 1.620366e-04 -     -
8 GAS1_N506F 559 1:S 529 -1.89 1.181587e-03 -     -
9 GAS1_N506H 559 1:P 529 2.13 4.409850e-04 -     -
10 GAS1_N506I 559 1:N 529 -3.10 1.548573e-03 -     -
11 GAS1_N506K 559 1:P 529 3.41 3.118482e-04 -     -
12 GAS1_N506L 559 1:N 529 -2.21 1.269822e-03 -     -
13 GAS1_N506M 559 1:N 529 -3.72 1.771691e-03 -     -
14 GAS1_N506P 559 1:S 529 0.46 6.753176e-04 -     -
15 GAS1_N506Q 559 1:P 529 2.64 3.848845e-04 -     -
16 GAS1_N506R 559 1:S 529 -0.55 8.637482e-04 -     -
17 GAS1_N506T 559 1:P 529 2.84 3.642562e-04 -     -
18 GAS1_N506V 559 1:S 529 -1.42 1.059623e-03 -     -
19 GAS1_N506W 559 1:N 530 -6.08 2.877705e-03 -     -
20 GAS1_N506Y 559 1:S 529 -1.71 1.134737e-03 -     -
N   Protein Length Quality Site Score PValue Alternative Site Score PValue Experiment
21 GAS1_del_N 558 1:P 528 3.69 2.884867e-04 2:P 523 2.96 3.525538e-04 anchored
22 GAS1_iT_G 560 1:P 528 12.56 1.599379e-05 2:P 529 9.05 5.608069e-05 anchored
23 GAS1_iT_S 560 1:P 528 12.92 1.397892e-05 2:P 529 10.61 3.274377e-05 anchored
24 GAS1_iT_N 560 1:P 528 10.70 3.164625e-05 2:P 529 8.94 5.814493e-05 anchored
25 GAS1_iTN_G 561 1:P 528 9.47 4.863512e-05 2:P 529 6.30 1.349533e-04 anchored
26 GAS1_dT_G 558 1:P 528 12.57 1.596536e-05 2:P 529 6.95 1.106172e-04 anchored
27 GAS1_dT_S 558 1:P 528 12.92 1.395377e-05 2:P 529 8.46 6.807738e-05 anchored
28 GAS1_dT_N 558 1:P 528 10.71 3.159352e-05 2:P 529 6.67 1.206730e-04 anchored
29 GAS1_dN_G 558 1:P 528 11.86 2.081267e-05 2:P 529 7.15 1.038989e-04 anchored
30 GAS1_dTN_G 557 1:P 528 13.70 1.028939e-05 2:P 522 3.55 3.006420e-04 anchored
31 GAS1_N510K 559 1:P 528 13.55 1.092765e-05 2:P 529 5.21 1.872418e-04 anchored
32 GAS1_N510T 559 1:P 528 13.49 1.119390e-05 2:P 529 5.20 1.878540e-04 anchored
33 GAS1_N512E 559 1:P 528 13.56 1.089167e-05 2:P 529 5.66 1.639660e-04 anchored
34 GAS1_N512A 559 1:P 528 13.86 9.659940e-06 2:P 529 4.36 2.390889e-04 anchored
35 GAS1_NGG 559 1:P 528 14.67 6.978759e-06 2:P 529 8.34 7.095431e-05 anchored
36 GAS1_NAG 559 1:P 528 13.95 9.326595e-06 2:P 529 6.70 1.195200e-04 anchored
37 GAS1_NGA 559 1:P 528 15.31 5.354713e-06 2:P 529 8.21 7.407293e-05 anchored
38 GAS1_NAS 559 1:P 528 11.93 2.027897e-05 2:P 529 5.26 1.843767e-04 anchored
39 GAS1_NSA 559 1:P 528 12.98 1.364079e-05 2:P 529 8.30 7.176315e-05 anchored
40 GAS1_NTG 559 1:P 528 7.06 1.066547e-04 -     anchored
N   Protein Length Quality Site Score PValue Alternative Site Score PValue Experiment
41 GAS1_NGT 559 1:P 528 8.44 6.863343e-05 -     anchored
42 GAS1_NTS 559 1:P 528 3.30 3.215912e-04 -     anchored
43 GAS1_NST 559 1:P 528 4.36 2.389986e-04 -     anchored
44 GAS1_NSG 559 1:P 528 13.35 1.180032e-05 2:P 529 9.25 5.233597e-05 anchored
45 GAS1_NGS 559 1:P 528 13.67 1.043991e-05 2:P 529 7.72 8.673494e-05 anchored
46 GAS1_NAT 559 1:P 528 5.39 1.774198e-04 -     anchored
47 GAS1_NTA 559 1:P 528 5.38 1.780625e-04 -     anchored
48 GAS1_NAL 559 1:I 536 -6.11 2.895295e-03 -     anchored
49 GAS1_NLA 559 1:I 536 -6.15 2.918009e-03 -     anchored
50 GAS1_NAV 559 1:I 536 -5.55 2.593406e-03 -     anchored
51 GAS1_NVA 559 1:S 528 1.55 5.127875e-04 -     anchored
52 GAS1_GAA 559 1:P 528 15.60 4.743625e-06 2:P 529 6.01 1.473822e-04 anchored
53 GAS1_GAS 559 1:P 528 14.06 8.923528e-06 2:P 529 5.46 1.738851e-04 anchored
54 GAS1_GSA 559 1:P 528 15.18 5.650171e-06 2:P 529 8.50 6.723530e-05 anchored
55 GAS1_GAT 559 1:P 528 9.61 4.643193e-05 -     anchored
56 GAS1_GTA 559 1:P 528 10.32 3.623604e-05 -     anchored
57 GAS1_GST 559 1:P 528 9.03 5.646978e-05 -     anchored
58 GAS1_GTS 559 1:P 528 8.62 6.465582e-05 -     anchored
59 GAS1_GGA 559 1:P 528 15.53 4.899064e-06 2:P 529 7.94 8.082538e-05 anchored
60 GAS1_GGS 559 1:P 528 14.05 8.958032e-06 2:P 529 7.48 9.344501e-05 anchored
N   Protein Length Quality Site Score PValue Alternative Site Score PValue Experiment
61 GAS1_GGT 559 1:P 528 10.28 3.680757e-05 -     anchored
62 GAS1_GGS_1 559 1:P 528 13.86 9.676772e-06 2:P 529 6.79 1.162810e-04 anchored
63 GAS1_GGS_2 559 1:P 528 13.80 9.915102e-06 2:P 529 6.78 1.166829e-04 anchored
64 GAS1_GGS_3 559 1:P 528 13.87 9.644570e-06 2:P 529 7.24 1.010599e-04 anchored
65 GAS1_GGS_4 559 1:P 528 14.17 8.542886e-06 2:P 529 5.94 1.505606e-04 anchored



Last modified: 12th September 2003