Sequences with E-value BETTER than threshold (0.002) 396 e-109
395 e-109
368 e-100
348 2e-94
345 8e-94
345 8e-94
343 4e-93
332 8e-90
314 3e-84
291 2e-77
291 2e-77
285 1e-75
282 1e-74
277 3e-73
277 3e-73
275 2e-72
272 8e-72
271 2e-71
266 7e-70
254 3e-66
231 3e-59
224 3e-57
218 2e-55
216 7e-55
214 2e-54
213 5e-54
208 2e-52
204 3e-51
191 2e-47
190 4e-47
176 6e-43
176 8e-43
172 2e-41
171 2e-41
165 1e-39
150 5e-35
140 8e-32
138 3e-31
132 1e-29
130 4e-29
105 2e-21
104 3e-21
101 2e-20
Alignments
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
most likely an alpha 1,2 mannosyltransferase utilized
for addition of the fourth, side-branching mannose onto
the GPI core structure.; Smp3p [Saccharomyces
cerevisiae]
sp|Q04174|SMP3_YEAST SMP3 PROTEIN
pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
Length = 516
Score = 396 bits (1007), Expect = e-109
Identities = 186/534 (34%), Positives = 284/534 (52%), Gaps = 62/534 (11%)
Query: 4 INFNWRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDD-PAR 62
+ + W + + I + L SYIHPDEHFQ +E+L + + IPWEF+ AR
Sbjct: 2 MRYQWWLYLVYAIGL--MLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAAR 59
Query: 63 SLAPLYFIYGPLLYFIKFF-KLNLTALQIWYIARLQISILSWIITDFCLYWMLPS--KPE 119
S PL +YGPL ++ F ++ I Y RLQ ++++ C ++++P + E
Sbjct: 60 SYGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQ----NYVMYLLCYHFLIPKLIRDE 115
Query: 120 RIKAIF----FTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLN 175
R F TSY+T YQ H FSNSIETL L+ T+ +++D+ ++++Q N
Sbjct: 116 RKAVQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDM-----VNEKNIQRSN 170
Query: 176 KNKNLFYTGVLISLGIFNRITFPAFLILPGWFVM-KYVLKHYVSGLYLVMGFFSTTALLI 234
KN G++ S G+FNR+TFPAF+ LP + K+ H+ S L++ F ++ L +
Sbjct: 171 F-KNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFV 229
Query: 235 LVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQIL 294
L+DT ++ N ++I PLNNL YN +NL HG+HP YTH+LVN+PQI+
Sbjct: 230 LIDTNIYNN----------GKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIV 279
Query: 295 GPGLIFFVSKSY-TKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDF---TLKW 350
GP L+ + Y +ISGLLFLS HQELRFL+PL+PL + ++ +
Sbjct: 280 GPVLLLAIFSGYKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTL 339
Query: 351 VQPWMLY-TWYIFNIFMSILMGKLHQGGVVPVLD---HIKSEA-SVQVWWRTYTPPSWIL 405
V + TW +FNI M+ +MG HQ G++ L H ++E V +WW+TY+PP+W+
Sbjct: 340 VNKKIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMY 399
Query: 406 GSNSTETTHLGEK------LNDNKFI----NIVDCMGADSKEVQQILQTISTN---KPVY 452
SN+ + L +++ F +++D G D + + ++ + N P+
Sbjct: 400 MSNNLTVSSLINTQDGIESIDEVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLT 459
Query: 453 LITP------IASFKHFDESRFSPVWNYTFHLDLDHLDFAD---IQPGLGVYQL 497
L+TP + K P NY FHLDLDHLDF D +PGL VY +
Sbjct: 460 LVTPNSMTSELKKLKRDGTINLIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSI 513
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
Length = 516
Score = 395 bits (1006), Expect = e-109
Identities = 187/534 (35%), Positives = 283/534 (52%), Gaps = 62/534 (11%)
Query: 4 INFNWRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDD-PAR 62
+ + W + + I + L SYIHPDEHFQ +E+L + + IPWEF+ AR
Sbjct: 2 MRYQWWLYLVYAIGL--MLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAAR 59
Query: 63 SLAPLYFIYGPLLYFIKFF-KLNLTALQIWYIARLQISILSWIITDFCLYWMLPS--KPE 119
S PL +YGPL ++ F ++ I Y RLQ ++++ C ++++P + E
Sbjct: 60 SYGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQ----NYVMYLLCYHFLIPKLIRDE 115
Query: 120 RIKAIF----FTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLN 175
R F TSY+T YQ H FSNSIETL L+ T+ +++D+ +++Q N
Sbjct: 116 RKAVQFIKKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDM-----VNGKNIQRRN 170
Query: 176 KNKNLFYTGVLISLGIFNRITFPAFLILPGWFVM-KYVLKHYVSGLYLVMGFFSTTALLI 234
KN G++ S G+FNR+TFPAF+ LP + K+ H+ S L++ F ++ L +
Sbjct: 171 F-KNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFV 229
Query: 235 LVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQIL 294
L+DT ++ N ++I PLNNL YN +NL HG+HP YTH+LVN+PQIL
Sbjct: 230 LIDTNIYNN----------GKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIL 279
Query: 295 GPGLIFFVSKSY-TKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDF---TLKW 350
GP L+ + Y +ISGLLFLS HQELRFL+PL+PL + ++ +
Sbjct: 280 GPVLLLAIFSGYKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTL 339
Query: 351 VQPWMLY-TWYIFNIFMSILMGKLHQGGVVPVLD---HIKSEA-SVQVWWRTYTPPSWIL 405
V + TW +FNI M+ +MG HQ G++ L H ++E V +WW+TY+PP+W+
Sbjct: 340 VNKKIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMY 399
Query: 406 GSNSTETTHLGEK------LNDNKFI----NIVDCMGADSKEVQQILQTISTN---KPVY 452
SN+ + L +++ F +++D G D + + ++ + N P+
Sbjct: 400 MSNNLTVSSLINTQDGIESIDEVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLT 459
Query: 453 LITP------IASFKHFDESRFSPVWNYTFHLDLDHLDFAD---IQPGLGVYQL 497
L+TP + K P NY FHLDLDHLDF D +PGL VY +
Sbjct: 460 LVTPNSMTSELKKLKRDGTINLIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSI 513
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase -like protein [Arabidopsis
thaliana]
gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
Length = 548
Score = 368 bits (936), Expect = e-100
Identities = 93/458 (20%), Positives = 165/458 (35%), Gaps = 72/458 (15%)
Query: 9 RTFYLLTIVFRFVFT-LSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPL 67
R +L + FR V L +Y +PDEH+QSLEV I Y + WE++ L P+
Sbjct: 39 RRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGY-MTWEWKRGIRSYLHPM 97
Query: 68 YFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWML---PSKPERIKAI 124
F + L ++ L+ + RL SI S I D LY + ++
Sbjct: 98 LFAF--LYKLLQVTGLDT-PYIMIKAPRLMQSIFS-AIGDLYLYKLSDALYGGNVATWSL 153
Query: 125 FFTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTG 184
F ++ N FSN +ET+L ++ + +R N +
Sbjct: 154 FCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPV---------NRKWGL 204
Query: 185 VLISLGIFNRITFPAFLILPGWFVMK--YVLKHYVSGLYLVMGFFSTTALLILVDTILFG 242
V+ +L R T + G + ++ + +G L+D +++G
Sbjct: 205 VIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIG-SLVLGFTCLLDRLMYG 263
Query: 243 NINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQI---LGPGLI 299
S++I PLN L +N +G HP++ + + P I
Sbjct: 264 -------------SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSI 310
Query: 300 FFVSKSYTKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTL----------- 348
+ KS + L ++ L S++ H+E RF++P+LP+A +
Sbjct: 311 AGIIKSKNQKLSAL-ILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSS 369
Query: 349 -----------KWVQPW------MLYTWYIFNIFMSILMGKLHQGGVVPVLDHIKSEA-- 389
+ W +Y NI M++ M HQ G ++++ EA
Sbjct: 370 SSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYK 429
Query: 390 ----SVQVWWRTYTPPSWILGSNSTETTHLGEKLNDNK 423
S+ ++ P + + L + K
Sbjct: 430 GRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEK 467
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
Length = 554
Score = 348 bits (884), Expect = 2e-94
Identities = 99/440 (22%), Positives = 181/440 (40%), Gaps = 54/440 (12%)
Query: 12 YLLTIVFRFVFT-LSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPLYFI 70
L T+ R + L + PDE++QSLEV + + NY + WE+ + PL I
Sbjct: 64 LLFTLALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGY-LTWEWTERLRSYTYPL--I 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPS--KPERIKAIFFT- 127
+ + + + L IW I RL ++LS + D LY ++ E + +FF
Sbjct: 121 FASIYKILHLLGKDSVQLLIW-IPRLAQALLSAVA-DVRLYSLMKQLENQEVARWVFFCQ 178
Query: 128 STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLI 187
S+ T +N++ET+L ++ + ++ SK + + L+
Sbjct: 179 LCSWFTWYCCTRTLTNTMETVLTIIALFYYP----LEGSKSMNSVKYSS---------LV 225
Query: 188 SLGIFNRITFPAFL--ILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNIN 245
+L R T +L F + + +L +GF T +L +++D I FG
Sbjct: 226 ALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFV-TLSLSLMIDRIFFGQ-- 282
Query: 246 NVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFFVSKS 305
+ + N L +N +G HP++ + P ILG L FF+
Sbjct: 283 -----------WTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGC 331
Query: 306 YTKTTPF----LTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPWM---LYT 358
Y + +TV+ LL S++ H+E RF+ P+LP ++L ++ W L
Sbjct: 332 YLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSF 391
Query: 359 WYIFNIFMSILMGKLHQGGVVPVLDHIKSE---------ASVQVWWRTYTPPSWILGSNS 409
++ N+F+++ G +HQ G + V+ HI+ AS+ + ++ P +
Sbjct: 392 LFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCP 451
Query: 410 TETTHLGEKLNDNKFINIVD 429
L + + +D
Sbjct: 452 LPMRFLQCPPDLTGKSHYLD 471
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
GPI-anchor biosynthesis [Mus musculus]
dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
Length = 542
Score = 345 bits (878), Expect = 8e-94
Identities = 97/439 (22%), Positives = 170/439 (38%), Gaps = 54/439 (12%)
Query: 13 LLTIVFRFVFT-LSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPLYFIY 71
L TI R + L + PDE++QSLEV + +Y + WE+ + PL I+
Sbjct: 54 LFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGY-LTWEWTERLRGYTYPL--IF 110
Query: 72 GPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPS--KPERIKAIFFT-S 128
+ + + IW I RL ++LS + D LY +L E + +F
Sbjct: 111 ASIYKVLHLLGKDSVQFLIW-IPRLGQALLSAVA-DIRLYSLLKQLENQEVAQWVFLCQL 168
Query: 129 TSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLIS 188
S+ T +N++ET L + + +++ N +L++
Sbjct: 169 CSWFTWYCCTRTLTNTMETSLTALALFYYP-------------LEGSRSVNSIKYSLLVA 215
Query: 189 LGIFNRITFPAFL--ILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNINN 246
L R T +L F + H +L +GF T +L +++D I FG
Sbjct: 216 LACVVRPTALIPWVPLLFRHFYQEQRKLHLTLHHFLPVGFI-TFSLSLIIDRIFFGQ--- 271
Query: 247 VVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFFVSKSY 306
+ + LN L +N +G HP++ ++ P +LG L FF+ +
Sbjct: 272 ----------WTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCF 321
Query: 307 TKTTPF----LTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPW---MLYTW 359
LTV+ LL S++ H+E RF+ P+LP ++L ++ W L
Sbjct: 322 LAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHLKTWRKAALSFL 381
Query: 360 YIFNIFMSILMGKLHQGGVVPVLDHIKSE-------ASVQVWWRTYTPPSWILGSNSTE- 411
+ N+ ++ G +HQ G + V++HI+ AS V+ +
Sbjct: 382 LLSNVPLAFYTGLVHQRGTLDVMNHIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCPL 441
Query: 412 -TTHLGEKLNDNKFINIVD 429
L + +D
Sbjct: 442 SMRFLQCPPDLTGKTQYLD 460
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
(EC 2.4.1.130) PIGB - human
dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
Length = 554
Score = 345 bits (878), Expect = 8e-94
Identities = 100/440 (22%), Positives = 181/440 (40%), Gaps = 54/440 (12%)
Query: 12 YLLTIVFRFVFT-LSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPLYFI 70
L TI R + L + PDE++QSLEV + + NY + WE+ + PL I
Sbjct: 64 LLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGY-LTWEWTERLRSYTYPL--I 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPS--KPERIKAIFFT- 127
+ + + + L IW I RL ++LS + D LY ++ E + +FF
Sbjct: 121 FASIYKILHLLGKDSVQLLIW-IPRLAQALLSAVA-DVRLYSLMKQLENQEVARWVFFCQ 178
Query: 128 STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLI 187
S+ T +N++ET+L ++ + ++ SK + + L+
Sbjct: 179 LCSWFTWYCCTRTLTNTMETVLTIIALFYYP----LEGSKSMNSVKYSS---------LV 225
Query: 188 SLGIFNRITFPAFL--ILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNIN 245
+L R T +L F + + +L +GF T +L +++D I FG
Sbjct: 226 ALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFV-TLSLSLMIDRIFFGQ-- 282
Query: 246 NVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFFVSKS 305
+ + N L +N +G HP++ + P ILG L FF+
Sbjct: 283 -----------WTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGC 331
Query: 306 YTKTTPF----LTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPWM---LYT 358
Y + +TV+ LL S++ H+E RF+ P+LP ++L ++ W L
Sbjct: 332 YLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSF 391
Query: 359 WYIFNIFMSILMGKLHQGGVVPVLDHIKSE---------ASVQVWWRTYTPPSWILGSNS 409
++ N+F+++ G +HQ G + V+ HI+ AS+ + ++ P +
Sbjct: 392 LFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCP 451
Query: 410 TETTHLGEKLNDNKFINIVD 429
L + + +D
Sbjct: 452 LPMRFLQCPPDLTGKSHYLD 471
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein - Arabidopsis
thaliana
emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein [Arabidopsis
thaliana]
Length = 498
Score = 343 bits (872), Expect = 4e-93
Identities = 90/455 (19%), Positives = 160/455 (34%), Gaps = 89/455 (19%)
Query: 9 RTFYLLTIVFRFVFT-LSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPL 67
R +L + FR V L +Y +PDEH+QSLEV I Y + WE++ L P+
Sbjct: 39 RRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGY-MTWEWKRGIRSYLHPM 97
Query: 68 YFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAIFFT 127
F + L ++ L+ + RL SI S I D LY + + A + T
Sbjct: 98 LFAF--LYKLLQVTGLDT-PYIMIKAPRLMQSIFS-AIGDLYLYKLSDALYGGNVATWST 153
Query: 128 STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLI 187
+ + L Y + +SI+ + N + V+
Sbjct: 154 VLTIMGLYYWPCIRDSSIDYPV-----------------------------NRKWGLVIA 184
Query: 188 SLGIFNRITFPAFLILPGWFVMK--YVLKHYVSGLYLVMGFFSTTALLILVDTILFGNIN 245
+L R T + G + ++ + +G L+D +++G
Sbjct: 185 ALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIG-SLVLGFTCLLDRLMYG--- 240
Query: 246 NVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQI---LGPGLIFFV 302
S++I PLN L +N +G HP++ + + P I +
Sbjct: 241 ----------SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGI 290
Query: 303 SKSYTKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTL-------------- 348
KS + L ++ L S++ H+E RF++P+LP+A +
Sbjct: 291 IKSKNQKLSAL-ILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSV 349
Query: 349 --------KWVQPW------MLYTWYIFNIFMSILMGKLHQGGVVPVLDHIKSEA----- 389
+ W +Y NI M++ M HQ G ++++ EA
Sbjct: 350 TKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRV 409
Query: 390 -SVQVWWRTYTPPSWILGSNSTETTHLGEKLNDNK 423
S+ ++ P + + L + K
Sbjct: 410 KSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEK 444
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
Length = 579
Score = 332 bits (844), Expect = 8e-90
Identities = 122/471 (25%), Positives = 193/471 (40%), Gaps = 53/471 (11%)
Query: 18 FRFVFTL--SDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPA-RSLAPLYFIYGPL 74
R ++ L Y+HPDE FQS EV+ IL PWEF + RS+ I G
Sbjct: 44 LRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGST 103
Query: 75 LYFIKFFKL------NLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAIFFTS 128
+ ++ ++ ++ + RL ++ LS+ + + P +R A+ S
Sbjct: 104 FWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADRWNALALLS 163
Query: 129 TSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLIS 188
SY+TLV+ FSN+IE LL ++L+ +V + + G +++
Sbjct: 164 GSYVTLVFYTRTFSNTIEGLLFTWLLVLVSS--HVTWGPTRKEPAPGPRWRSWLLGGIVA 221
Query: 189 LGIFNRITFPAFLILPGWF-----VMKYVLKHYVS-GLYLVMGFFSTTALLILVDTILFG 242
G FNR TF AF ++P + LK L L+ G T A+ + D+ F
Sbjct: 222 AGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVLLPGATLTAAVFVATDSWYF- 280
Query: 243 NINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPG----- 297
+ P + ++ P+N L YN +NLA+HG H TH+ VN + G
Sbjct: 281 ------SSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQAL 334
Query: 298 ------------------LIFFVSKSYTKTTP----FLTVISGLLFLSVIPHQELRFLIP 335
L+ + ++P L L LS HQE RFLIP
Sbjct: 335 QAAWQQLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIP 394
Query: 336 LLPLACCSFDFTLKWVQPWMLYTWYIFNIFMSILMGKLHQGGVVPVLDHIKSEASVQVWW 395
LL + V PW T +FN ++L G LHQGG+VP L++++ V
Sbjct: 395 LLVPLVLLCSPQTQPV-PWK-GTVVLFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVLP 452
Query: 396 RTYTPPSWILGSNSTETTHLGEKLNDNKFINIVDCMGADSKEVQQILQTIS 446
T T + + HL + +VD G + + Q L++ +
Sbjct: 453 STPTHYTLLFTHTYMPPRHLLHLPGLGAPVEVVDMGGTEDWALCQTLKSFT 503
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
Length = 506
Score = 314 bits (797), Expect = 3e-84
Identities = 81/446 (18%), Positives = 149/446 (33%), Gaps = 70/446 (15%)
Query: 9 RTF-YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPL 67
R L L +Y +PDEH+Q LEV + Y + WE++ L P
Sbjct: 46 RRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGH-LTWEWKRGLRSYLHP- 103
Query: 68 YFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAIFFT 127
FI+ L + L+ + + RL S+ + D LY +
Sbjct: 104 -FIFAALYKILSLLHLD-SPWFMAMAPRLLQSVFA-SFGDLYLYKLSK------------ 148
Query: 128 STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNK----NLFYT 183
L++ NH+ +ET+L + + + + +K +
Sbjct: 149 ------LIFNNHV--AHMETVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMA 200
Query: 184 GVLISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYL--VMGFFSTTALLILVDTILF 241
++ +L R T + G +K ++L V A+ +D ++
Sbjct: 201 LLIAALACAIRPTSAITWLYVGLLDFIQ-MKSKSRFIFLEVVPLGVFVLAVTTFLDCWMY 259
Query: 242 GNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFF 301
G S II PLN L +N +G H ++ + P ++ L F
Sbjct: 260 G-------------SRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFS 306
Query: 302 VSKSYTKT--TPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPWMLY-- 357
+S ++ L+ S++ H+E RF++P+LP L +
Sbjct: 307 ISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGH 366
Query: 358 --------------TWYIFNIFMSILMGKLHQGGVVPVLDHIKSEAS------VQVWWRT 397
+ N+ M++ M HQ G + ++ EA V
Sbjct: 367 NEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPC 426
Query: 398 YTPPSWILGSNSTETTHLGEKLNDNK 423
++ P + + L ++NK
Sbjct: 427 HSTPYYSTLHYNLPMRFLDCTPSENK 452
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
Length = 512
Score = 291 bits (738), Expect = 2e-77
Identities = 78/455 (17%), Positives = 147/455 (32%), Gaps = 93/455 (20%)
Query: 10 TFYLLTIVFRFVFT---LSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAP 66
Y+ ++ + +Y PDE++QSLEV Y + WE+ + P
Sbjct: 3 LIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGY-LTWEWVQGIRSYVYP 61
Query: 67 LYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAIFF 126
L L + +L+ L + + R+ R A+F
Sbjct: 62 LLIA--GLYKILALLQLDSAHLLV-VLPRI-----------------------RKWALFL 95
Query: 127 TSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVL 186
+ + +N++E L + + ++ +
Sbjct: 96 ILVPWFWFYTGSRTLANTLEASLTTIALSYFP--------------WYGESTAYLW---P 138
Query: 187 ISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYL---VMGFFSTTALLILVDTILFGN 243
++ F R T LP + V L L V+ L I +DT G
Sbjct: 139 AAICCFLRPTAAVIW-LPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQ 197
Query: 244 INNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFFVS 303
+ I+ P L YN + +G HP++ + V +P +LG + F+
Sbjct: 198 L-------------IVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIF 244
Query: 304 KS---------YTKTTPFL-TVISGLLFLSVIPHQELRFLIPLLPLAC-----CSFDFTL 348
Y + L T+ L+ LS + H+E RF+ PLLPL +++
Sbjct: 245 GVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSI 304
Query: 349 KWVQP--WMLYTWYIF-NIFMSILMGKLHQGGVVPVLDHIKSEAS-----------VQVW 394
+ W + N+ + + +HQ G + ++ ++ A +
Sbjct: 305 RASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFL 364
Query: 395 WRTYTPPSWILGSNSTETTHLGEKLNDNKFINIVD 429
++ P + + L + N K D
Sbjct: 365 MPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKD 399
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
(Schizosaccharomyces pombe)
emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
[Schizosaccharomyces pombe]
Length = 506
Score = 291 bits (738), Expect = 2e-77
Identities = 78/442 (17%), Positives = 158/442 (35%), Gaps = 36/442 (8%)
Query: 11 FYLLTIVFRFVFTLS-DSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPLYF 69
F+L +VFR+ L ++ PDE +QSLEV + I Y + WE+ +L PL
Sbjct: 5 FWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGF-LTWEWTSAIRSALHPL-- 61
Query: 70 IYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIIT-DFCLYWMLPSKPERIKAIFFTS 128
I+ L ++ KL+ + +L + I+ + ++ + S
Sbjct: 62 IFAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKTANWTLACS 121
Query: 129 T-SYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLI 187
S + FSNS+ET L + Y++ Q +L +
Sbjct: 122 LVSIMNAYVGVRTFSNSLETTLTSIGFYYFS--YYLKYENSSPEQRKKAYSSLLGFISVA 179
Query: 188 SLGIFNRITFPAFLILPGWF-----------VMKYVLKHYVSGLYLVMGFFSTTALLILV 236
+ F R T I P F ++ + +G+ + +L
Sbjct: 180 AFACFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLC 239
Query: 237 DTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGP 296
++ + N++A+ ++ ++ +N + +G++ ++ ++ +P I G
Sbjct: 240 VSLF---LVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGG 296
Query: 297 GLIFFVSKSYTKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPWM- 355
L F + +T T++ S+I H+ELRF+ P+ P+ W
Sbjct: 297 FLPFVLLTMDLQT--AGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFFSSFSSWKR 354
Query: 356 -LYTWYIFNIFMSI---LMGKLHQGGVVPVLDHIKSEASVQV--WWRTYTPPSWILGSNS 409
+++ + ++ + + HQ GV+ V+ I S A +
Sbjct: 355 AARFFFLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKNQTGLILAPCHTTPWQSHIH 414
Query: 410 TET-----THLGEKLNDNKFIN 426
+ L + + F
Sbjct: 415 SPFAENGWKFLTCEPFEKPFDE 436
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
Length = 558
Score = 285 bits (724), Expect = 1e-75
Identities = 85/466 (18%), Positives = 169/466 (36%), Gaps = 65/466 (13%)
Query: 8 WRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPL 67
W L I F+ + PDE +QS EV N + +PWE++ L P
Sbjct: 3 WWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGH-LPWEWRYGLRSVLFPA 61
Query: 68 YFIYGPLLYFIKFFKLNLTALQIWYIARLQISI------LSWIITDFCLYWMLPSK---- 117
Y +K + T +W+ R+ ++ +S L +L +
Sbjct: 62 VVALP--FYLLKLLGRDTT-WAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELEL 118
Query: 118 PERIKAIFFTSTSYITLVYQNHLFS---NSIETLLLLVTILLIDDLRYVQESKDQDVQNL 174
E + SY V + NSI LL+++ ++ L
Sbjct: 119 AEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEAL 178
Query: 175 -----NKNKNLFYTGVLISLGIFNRITFPAFL--ILPGWFVMKYVLKHYVSGLY--LVMG 225
+ + +L L R+T L ++ ++ GL+ ++ G
Sbjct: 179 LVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTG 238
Query: 226 FFSTTAL---LILVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPY 282
A+ ++++D +G +++ PL +N + G HP+
Sbjct: 239 LIVLVAVLGGVMVLDYCFYG-------------RWVLTPLAFFRFNVLHNLSRFFGEHPW 285
Query: 283 YTHILVNMPQILGPGLIFFV---------SKSYTKTTPFLTVI----SGLLFLSVIPHQE 329
Y ++ + I+GP ++F + + S + P L ++ L F S+I H+E
Sbjct: 286 YFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKE 345
Query: 330 LRFLIPLLPL-ACCSFDFTLKWVQP-----WMLYTWYIFNIFMSILMGKLHQGGVVPVLD 383
+RF+ ++PL + ++W + M + +FNI M LMG +++ G + V+
Sbjct: 346 MRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMA 405
Query: 384 HIKSEASVQ---VWWRTYTPPSWILGSNSTE-TTHLGEKLNDNKFI 425
++ + V YT P + + ++ ++
Sbjct: 406 EVRDGPRINRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKT 451
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
Length = 533
Score = 282 bits (716), Expect = 1e-74
Identities = 120/442 (27%), Positives = 203/442 (45%), Gaps = 49/442 (11%)
Query: 5 NFNWRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEF-QDDPARS 63
N + Y ++ RF F+ SYIHPDEH QS ++ N++ + +PWEF P RS
Sbjct: 4 NRKYAIIYTFLLILRFWFSQGSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRS 63
Query: 64 LAPLYFIYGPLLYFIK-FFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK 122
+ PL + P+ + K N + I RL + ++S +I D ++ ++P R
Sbjct: 64 VVPLNVMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLI-DLSIWNIVPLNA-RWS 121
Query: 123 AIFFTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFY 182
A+ S+S++ +Q H F+NSIET+ +TIL + L V F
Sbjct: 122 ALLLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPL------NKKISYLYTFL 175
Query: 183 TGVLISLGIFNRITFPAFLILPGWFVMKYVLKHYV---SGLYLVMGFFSTTALLILVDTI 239
++ LG F RITF AF+I P + K V ++L + F + + ++ I
Sbjct: 176 LAIVSVLGFFTRITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACI 235
Query: 240 LFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLI 299
L + ++I NNL YN++ ENL+QHG+H TH NMP + GP +
Sbjct: 236 L--------EDYKFYGVFVITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGPLI- 286
Query: 300 FFVSKSYTKTTPF-LTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPWMLYT 358
FV K + P + + LS+ PHQE RFL+P + + ++ W+ +
Sbjct: 287 -FVPKLWDVRKPATWLWLLPVFILSLFPHQEPRFLLPAASIFIVNSGCLVR--SYWIKFL 343
Query: 359 WYIFNIFMSILMGKLHQGGVVPVLDHIKS--------------------EASVQVWWRTY 398
+ ++ + +++ G +HQ GV+P + +K+ + +W+ Y
Sbjct: 344 FVMYAVVLAVFFGIMHQNGVIPAVLEVKNIIEQRNVTTMENCNLYFNPEMPTTIYFWKIY 403
Query: 399 TPPSWILGS---NSTETTHLGE 417
+ P+W+L + T+HL
Sbjct: 404 SAPTWMLARPKFSQINTSHLYN 425
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
Length = 611
Score = 277 bits (703), Expect = 3e-73
Identities = 73/440 (16%), Positives = 134/440 (29%), Gaps = 92/440 (20%)
Query: 12 YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPLYFI 70
+ + R L + DE F E I WE+ RS A L
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQ-TWEYSPAYAIRSYAYLLLH 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--AIFFTS 128
P + + L + ++Y R ++ +S I + + + + F
Sbjct: 121 AWPAAFHARI--LQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLV 178
Query: 129 TSYITLVYQNHLF---SNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGV 185
S + + F S + T L+ +T + D+ + G
Sbjct: 179 LS-TGMFCSSSAFLPSSFCMYTTLIAMTGWYM----------DKTSIAVLGVAAGAILGW 227
Query: 186 LISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNIN 245
S I VMK+ K + + +M ++++D+ +G +
Sbjct: 228 PFSAA-------LGLPIAFDLLVMKHRWKSF--FHWSLMALILFLVPVVVIDSYYYGKL- 277
Query: 246 NVVAEPFNISSYIIAPLNNLLYNAR-YENLAQHGIHPYYTHI---LVNMPQILGPGLIFF 301
+IAPLN +LYN +G P+Y ++ +N L+
Sbjct: 278 ------------VIAPLNIVLYNVFTPHGPDLYGTEPWYFYLIKGFLNFNVAFALALLVL 325
Query: 302 VSKSY-----------TKTTPFLTVISGL----LFLSVIPHQELRFLIPLLPLACCSFDF 346
S P+ ++ + + + PH+E RFL P+ PL C
Sbjct: 326 PLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAV 385
Query: 347 TLKWVQP--------------------WMLYTWYIFNIFM-----SILMGKLHQGGVVPV 381
L +Q L T ++F + ++ G H G + +
Sbjct: 386 ALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRG-YH--GPLDL 442
Query: 382 LDHIKSEASVQVWWRTYTPP 401
A+ +T P
Sbjct: 443 YPEFYRIATDP---TIHTVP 459
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
Length = 611
Score = 277 bits (703), Expect = 3e-73
Identities = 73/440 (16%), Positives = 134/440 (29%), Gaps = 92/440 (20%)
Query: 12 YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPLYFI 70
+ + R L + DE F E I WE+ RS A L
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQ-TWEYSPAYAIRSYAYLLLH 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--AIFFTS 128
P + + L + ++Y R ++ +S I + + + + F
Sbjct: 121 AWPAAFHARI--LQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLV 178
Query: 129 TSYITLVYQNHLF---SNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGV 185
S + + F S + T L+ +T + D+ + G
Sbjct: 179 LS-TGMFCSSSAFLPSSFCMYTTLIAMTGWYM----------DKTSIAVLGVAAGAILGW 227
Query: 186 LISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNIN 245
S I VMK+ K + + +M ++++D+ +G +
Sbjct: 228 PFSAA-------LGLPIAFDLLVMKHRWKSF--FHWSLMALILFLVPVVVIDSYYYGKL- 277
Query: 246 NVVAEPFNISSYIIAPLNNLLYNAR-YENLAQHGIHPYYTHI---LVNMPQILGPGLIFF 301
+IAPLN +LYN +G P+Y ++ +N L+
Sbjct: 278 ------------VIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALALLVL 325
Query: 302 VSKSY-----------TKTTPFLTVISGL----LFLSVIPHQELRFLIPLLPLACCSFDF 346
S P+ ++ + + + PH+E RFL P+ PL C
Sbjct: 326 PLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAV 385
Query: 347 TLKWVQP--------------------WMLYTWYIFNIFM-----SILMGKLHQGGVVPV 381
L +Q L T ++F + ++ G H G + +
Sbjct: 386 ALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRG-YH--GPLDL 442
Query: 382 LDHIKSEASVQVWWRTYTPP 401
A+ +T P
Sbjct: 443 YPEFYRIATDP---TIHTVP 459
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
musculus]
Length = 611
Score = 275 bits (697), Expect = 2e-72
Identities = 71/441 (16%), Positives = 134/441 (30%), Gaps = 94/441 (21%)
Query: 12 YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPLYFI 70
+ + R L + DE F E I WE+ RS A L
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQ-TWEYSPVYAIRSYAYLLLH 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--AIFFTS 128
P + + L + ++Y R ++ +S + + + + + F
Sbjct: 121 AWPAAFHARI--LQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLV 178
Query: 129 TSYITLVYQNHLF---SNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGV 185
S + + F S + T L+ +T +D
Sbjct: 179 LS-TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTPIAVLG------------------- 218
Query: 186 LISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYL-VMGFFSTTALLILVDTILFGNI 244
++ G F A L LP F + + S L ++ ++++D+ +G +
Sbjct: 219 -VAAGAILGWPFSAALGLPIAFDLLARKHRWKSFLLWSLVALALFLVPVVVIDSYYYGKL 277
Query: 245 NNVVAEPFNISSYIIAPLNNLLYNAR-YENLAQHGIHPYYTHI---LVNMPQILGPGLIF 300
++APLN +LYN +G P+Y ++ +N L+
Sbjct: 278 -------------VVAPLNIVLYNVFTSHGPDLYGTEPWYFYLINGFLNFNVAFALALLV 324
Query: 301 FVSK-----------SYTKTTPFLTVISGL----LFLSVIPHQELRFLIPLLPLACCSFD 345
P+ ++ + + + PH+E RFL P+ PL C
Sbjct: 325 LPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGA 384
Query: 346 FTLKWVQP--------------------WMLYTWYIFNIFM-----SILMGKLHQGGVVP 380
L +Q L T ++F + ++ G H G +
Sbjct: 385 VALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRG-YH--GPLD 441
Query: 381 VLDHIKSEASVQVWWRTYTPP 401
+ A+ +T P
Sbjct: 442 LYPEFYRIATDP---TIHTVP 459
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
Length = 618
Score = 272 bits (691), Expect = 8e-72
Identities = 73/447 (16%), Positives = 134/447 (29%), Gaps = 99/447 (22%)
Query: 12 YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPLYFI 70
+ + R L + DE F E I WE+ RS A L
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQ-TWEYSPAYAIRSYAYLLLH 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--AIFFTS 128
P + + L + ++Y R ++ +S I + + + + F
Sbjct: 121 AWPAAFHARI--LQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLV 178
Query: 129 TSYITLVYQNHLF---SNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGV 185
S + + F S + T L+ +T + D+ + G
Sbjct: 179 LS-TGMFCSSSAFLPSSFCMYTTLIAMTGWYM----------DKTSIAVLGVAAGAILGW 227
Query: 186 LISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNIN 245
S I VMK+ K + + +M ++++D+ +G +
Sbjct: 228 PFSAA-------LGLPIAFDLLVMKHRWKSF--FHWSLMALILFLVPVVVIDSYYYGKL- 277
Query: 246 NVVAEPFNISSYIIAPLNNLLYNAR-YENLAQHGIHPYYTHI---LVNMPQILGPGLIFF 301
+IAPLN +LYN +G P+Y ++ +N L+
Sbjct: 278 ------------VIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGFLNFNVAFALALLVL 325
Query: 302 VSKSY-----------TKTTPFLTVISGL----LFLSVIPHQELRFLIPLLPLACCSFDF 346
S P+ ++ + + + PH+E RFL P+ PL C
Sbjct: 326 PLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAV 385
Query: 347 TLKWVQPWMLYT---------------------------WYIFNIFM-----SILMGKLH 374
L +Q LY ++F + ++ G H
Sbjct: 386 ALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRG-YH 444
Query: 375 QGGVVPVLDHIKSEASVQVWWRTYTPP 401
G + + A+ +T P
Sbjct: 445 --GPLDLYPEFYRIATDP---TIHTVP 466
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
Length = 618
Score = 271 bits (687), Expect = 2e-71
Identities = 73/447 (16%), Positives = 134/447 (29%), Gaps = 99/447 (22%)
Query: 12 YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPLYFI 70
+ + R L + DE F E I WE+ RS A L
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQ-TWEYSPAYAIRSYAYLLLH 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--AIFFTS 128
P + + L + ++Y R ++ +S I + + + + F
Sbjct: 121 AWPAAFHARI--LQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLV 178
Query: 129 TSYITLVYQNHLF---SNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGV 185
S + + F S + T L+ +T + D+ + G
Sbjct: 179 LS-TGMFCSSSAFLPSSFCMYTTLIAMTGWYM----------DKTSIAVLGVAAGAILGW 227
Query: 186 LISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNIN 245
S I VMK+ K + + +M ++++D+ +G +
Sbjct: 228 PFSAA-------LGLPIAFDLLVMKHRWKSF--FHWSLMALILFLVPVVVIDSYYYGKL- 277
Query: 246 NVVAEPFNISSYIIAPLNNLLYNAR-YENLAQHGIHPYYTHI---LVNMPQILGPGLIFF 301
+IAPLN +LYN +G P+Y ++ +N L+
Sbjct: 278 ------------VIAPLNIVLYNIFTPHGPDLYGTEPWYFYLINGFLNFNVAFALALLVL 325
Query: 302 VSKSY-----------TKTTPFLTVISGL----LFLSVIPHQELRFLIPLLPLACCSFDF 346
S P+ ++ + + + PH+E RFL P+ PL C
Sbjct: 326 PLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICLCGAV 385
Query: 347 TLKWVQPWMLYT---------------------------WYIFNIFM-----SILMGKLH 374
L +Q LY ++F + ++ G H
Sbjct: 386 ALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRG-YH 444
Query: 375 QGGVVPVLDHIKSEASVQVWWRTYTPP 401
G + + A+ +T P
Sbjct: 445 --GPLDLYPEFYRIATDP---TIHTVP 466
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
Length = 457
Score = 266 bits (674), Expect = 7e-70
Identities = 100/400 (25%), Positives = 158/400 (39%), Gaps = 55/400 (13%)
Query: 80 FFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAIFFTSTSYITLVYQNH 139
++ L+ ++L + T C W +R A+ S SY+TLV+
Sbjct: 4 WWGLDSSSLPFP-----------LLWTGPCTTWPPAMGADRWNALALLSGSYVTLVFYTR 52
Query: 140 LFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLISLGIFNRITFPA 199
FSN+IE LL ++L+ +V + + G +++ G FNR TF A
Sbjct: 53 TFSNTIEGLLFTWLLVLVSS--HVTWGPTRKEPAPGPRWRSWLLGGIVAAGFFNRPTFLA 110
Query: 200 FLILPGWF-----VMKYVLKHYVS-GLYLVMGFFSTTALLILVDTILFGNINNVVAEPFN 253
F ++P + LK L L+ G T A+ + D+ F + P
Sbjct: 111 FAVVPLYLWGTRGATNPGLKSLTREALVLLPGATLTAAVFVATDSWYF-------SSPAT 163
Query: 254 ISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPG---------------- 297
+ ++ P+N L YN +NLA+HG H TH+ VN + G
Sbjct: 164 SRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGL 223
Query: 298 -------LIFFVSKSYTKTTP----FLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDF 346
L+ + ++P L L LS HQE RFLIPLL
Sbjct: 224 QASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSP 283
Query: 347 TLKWVQPWMLYTWYIFNIFMSILMGKLHQGGVVPVLDHIKSEASVQVWWRTYTPPSWILG 406
+ V PW T +FN ++L G LHQGG+VP L++++ V T T + +
Sbjct: 284 QTQPV-PWK-GTVALFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVLPSTPTHYTLLFT 341
Query: 407 SNSTETTHLGEKLNDNKFINIVDCMGADSKEVQQILQTIS 446
HL + +VD G + + Q L++ +
Sbjct: 342 HTYMPPRHLLHLPGLGAPVEVVDMGGTEDWALCQTLKSFT 381
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
Length = 830
Score = 254 bits (643), Expect = 3e-66
Identities = 112/509 (22%), Positives = 184/509 (36%), Gaps = 110/509 (21%)
Query: 11 FYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDP--ARSLAPLY 68
F + VF Y+HPDE FQS+EV+T WEF + + P
Sbjct: 21 FCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFA 80
Query: 69 FIYGPLLYFIKFFKLNLTALQIWY------------IARLQISILSWIITDFCLYWMLPS 116
+ P F++ L+ W+ RL +++S+ D+CL+ +
Sbjct: 81 LLRIPW----SFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISF-SNDYCLFRICRL 135
Query: 117 KPERIKA-IFFTSTSYITLVYQNHLFSNSIETLL-----------LLVTILLIDDLRYVQ 164
R + + +S+I LV+ FSNS+E + +L T ++ +++
Sbjct: 136 YGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLE 195
Query: 165 ESKDQDV-----------QNLNKNKNLFYTGVLI---SLGIFNRITFPAFLILPGWFVMK 210
E D+ +N NL + + G+FNR TF F V
Sbjct: 196 EKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLF---GAPMVFF 252
Query: 211 YVLKHY------VSGLYLVMGFFSTTA-----LLILVDTILFGNINN--VVAEPFNISSY 257
++L+ L + F A L I D++ + ++ + +I ++
Sbjct: 253 WLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNF 312
Query: 258 IIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQI-----------LGPGLIFFVSKSY 306
+ P N + N A HG+HP Y H++VNMP + L+ F Y
Sbjct: 313 VFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEY 372
Query: 307 TKTTPF--------LTVISGLLFLSVIPHQELRFLIPLL--------------------- 337
F + L FLS+I HQE RFL+P+
Sbjct: 373 QVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPF 432
Query: 338 ----PLACCSFDFTLK--WVQPWMLYTWYIFNIFMSILMGKLHQGGVVPVLDHIKSEASV 391
PL +D L P++L WY+ N+ +++ G +HQ GV P+ I V
Sbjct: 433 QKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADIS---HV 489
Query: 392 QVWWRTYTPPSWILGSNSTETTHLGEKLN 420
T I + HL +
Sbjct: 490 IATKPAATHVHLITSHIYSLPLHLINIPS 518
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
- fission yeast (Schizosaccharomyces pombe)
emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
[Schizosaccharomyces pombe]
Length = 577
Score = 231 bits (584), Expect = 3e-59
Identities = 60/378 (15%), Positives = 119/378 (30%), Gaps = 51/378 (13%)
Query: 9 RTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPL 67
TF +L + R DE + E L + Y WE+ RS +
Sbjct: 16 WTFSILAV-LRLTSASFRVIDDCDEVYNYWEPLHYLLYGYGLQ-TWEYSPEYAIRSWFYI 73
Query: 68 YFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAIFFT 127
P L L+ L ++Y R ++ S + L + R A+ T
Sbjct: 74 ALHAVPGFL---ARGLGLSRLHVFYFIRGVLACFS-AFCETNLILAVARNFNRAVALHLT 129
Query: 128 STSYIT---LVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTG 184
S ++ +S ++ + + + S + V+ ++ G
Sbjct: 130 SVLFVNSGMWSASTSFLPSSFAMNMVTLAL----SAQLSPPSTKRTVKVVSFITIGAVIG 185
Query: 185 VLISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNI 244
S + F ++ +++ + +++ + T + I VD++ + I
Sbjct: 186 WPFSAALSI--PFILLELVDLKGRFRHLFCRWFKAIFVAL---LITGICITVDSLFYHRI 240
Query: 245 NNVVAEPFNISSYIIAPLNNLLYNARYE---NLAQHGIHPYYTHILVN---------MPQ 292
N + YN + +G P++ +
Sbjct: 241 Q-------------FVAWNIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAM 287
Query: 293 ILGPGLIFFVSKSYTKTTPFL---TVISG----LLFLSVIPHQELRFLIPLLPLACCSFD 345
GP ++ ++ FL +VIS L + PH+E RF+ P+ P+ C +
Sbjct: 288 ACGPLVLLAAFTNWINLDSFLDLSSVISPFYIWLFIFIIQPHKEERFMYPIYPVLCLAAA 347
Query: 346 FTLKWVQPWMLYTWYIFN 363
L M+ N
Sbjct: 348 IGLDMSLKLMIQILSSIN 365
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
Length = 623
Score = 224 bits (567), Expect = 3e-57
Identities = 59/372 (15%), Positives = 104/372 (27%), Gaps = 61/372 (16%)
Query: 12 YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD--DPARSLAPLYF 69
+ + R + DE F E L I + WE+ L
Sbjct: 77 FKTFVSARLCSAIWAYIADCDETFNYWEPLHYIINGHGLQ-TWEYSPQFGLRSYTY-LLL 134
Query: 70 IYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--AIFFT 127
P ++ K F N + + I+Y+ R + ++ + + I + F
Sbjct: 135 QGVPGYFYQKLF--NPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQ 192
Query: 128 STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLI 187
S V L +S +N + L
Sbjct: 193 LFSVGMFVSSTALLPSSFSM--------YFGCAALAAWW----------QQNYCFAIFLT 234
Query: 188 SLGIFNRITFPAFLILPGWFVMKYVLKHYVSGL-YLVMGFFSTTALLILVDTILFGNINN 246
++ F A + +P M + + + + + ++ + +I +DT FG +
Sbjct: 235 AISALLGWPFAALIGIPLVLEMLLRQRDWKTFVQWTLISGATVAIPMIAIDTSYFGKL-- 292
Query: 247 VVAEPFNISSYIIAPLNNLLYNAR-YENLAQHGIHPYYTHILVNMP-----QILGPGLIF 300
APLN + YN G P +I+ +L L
Sbjct: 293 -----------TFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNFNIIWLLALQLPI 341
Query: 301 FVSKSYT--------------KTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDF 346
+ Y + + LL PH+E RFL P+ PL
Sbjct: 342 MLVIDYLIVPAKSKSTLNFPHYISLAPLYLW-LLVFFAQPHKEERFLFPIYPLISLCGAI 400
Query: 347 TLKWVQPWMLYT 358
T+ Q
Sbjct: 401 TVDVYQRIFFRM 412
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
Length = 919
Score = 218 bits (552), Expect = 2e-55
Identities = 58/358 (16%), Positives = 109/358 (30%), Gaps = 61/358 (17%)
Query: 8 WRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD--DPARSLA 65
W ++ R++ S+ DE F E L + WE+ L
Sbjct: 395 WFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPLHYILYKSGFQ-TWEYSSNFALRSYLY 453
Query: 66 PLYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--A 123
++ L + ++++Y RL + ++S + + + +RI A
Sbjct: 454 ---ILFHELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYA 510
Query: 124 IFFTSTSYITLVYQNHLFSNSIET--LLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLF 181
+ + +S + L +LL +
Sbjct: 511 VAMLCLTSGCFFASTSFLPSSFSMYAISLSSGLLLFEK--------------------YA 550
Query: 182 YTGVLISLGIFNRITFPAFLILP-GWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTIL 240
+ +G+ F LP + + K + + +LVD
Sbjct: 551 MAVAVSVVGVILGWPFSILAFLPVVIYSLVKRFKQAFIAG--AVTTIFLLGVSLLVDYYY 608
Query: 241 FGNINNVVAEPFNISSYIIAPLNNLLYNARYEN-LAQHGIHPYYTHI--------LVNMP 291
+ + + LN L+YN +G +I +
Sbjct: 609 Y-------------KRWTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNGFNNFNFCFIL 655
Query: 292 QILGPGLIFFVSKSYTKTTPFLTVISG----LLFLSVIPHQELRFLIPLLPLACCSFD 345
+L + + + Y + L VIS L F+S+ PH+E RFL P+ PL C S
Sbjct: 656 AMLFVAIYPVIRRKYDR--ALLVVISPMYIWLAFMSLQPHKEERFLYPIYPLICVSAS 711
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
could be the target of the GPI synthesis inhibitor,
YW3548; Most likely an alpha 1,2 mannosyltransferase
utilized for the addition of the third mannose onto the
GPI core structure.; Gpi1>
sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
cerevisiae)
emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
Length = 616
Score = 216 bits (546), Expect = 7e-55
Identities = 64/398 (16%), Positives = 133/398 (33%), Gaps = 70/398 (17%)
Query: 64 LAPLYFIYGPLLYFIKFFKLNLT----ALQIWYIARLQISILSWIITDFCLYWMLPSKPE 119
L P Y + + +K ++T + Y ++ +++L+ I ++ + +
Sbjct: 107 LLPKYELSWQVAEDLKRLPFDVTRSFEYYGVIYAPKIVMAVLA-SIGEYYIVRFVQKLYL 165
Query: 120 ---------------------RIKAIFFTSTSYITLVYQNHLFSNSIETLLLLVTILLID 158
A+ + T++ + F NS E +L + + D
Sbjct: 166 LTLDKRNEKEEEERRSGLSEITKFALLLSLTNFFNCFFITRTFINSFEMILTSIALYYWD 225
Query: 159 DLRYVQESKDQDVQNLNKNKNLFYTGVLISLGIFNRITFPAFLILPGWFVMKYVLKHYVS 218
+ Q ++ + K+L + L R + ++P + L
Sbjct: 226 ------WTGGQMIKESSFTKSLIF----AFLACLQRPSSGLIWVIP-SISLILNLVGKKQ 274
Query: 219 GLYLVMGFFSTTALLILVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHG 278
L + F + N + + + L +N +G
Sbjct: 275 YHLLFITFSKVL------RSFFLVFTANAIIDMYFYEKVTFPFFRFLKFNFTTPLSKFYG 328
Query: 279 IHPYYTHILVNMPQILGPGLIFFVSKSYTKTT----------PF----LTVISGLLFLSV 324
+ P++ H ++P +LG + F + + PF LT++ LL S
Sbjct: 329 VAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYST 388
Query: 325 IPHQELRFLIPLLPLACC--SFDFTLKWVQPWM--------LYTWYIFNIFMSILMGKLH 374
+PH+E RF+ PL PL SF W L+ ++F+++L+ H
Sbjct: 389 LPHKEFRFIFPLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFH 448
Query: 375 QGGVVPVLDHIKSEA---SVQVWWRTYTPPSWILGSNS 409
+ G + V+ + E S+ ++ P S
Sbjct: 449 ESGSIEVMKFLHEEPEIDSLGFIMPCHSTPGQSYLHRS 486
Score = 65.3 bits (158), Expect = 3e-09
Identities = 13/60 (21%), Positives = 27/60 (44%), Gaps = 2/60 (3%)
Query: 11 FYLLTIVFRFVFTLSD-SYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPLYF 69
+ + + FR + + ++ DE +Q+LE + Y + WE++ L P+ F
Sbjct: 17 IFWVFLAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYG-ELTWEWKFGVRSYLFPMIF 75
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
Length = 678
Score = 214 bits (542), Expect = 2e-54
Identities = 61/404 (15%), Positives = 121/404 (29%), Gaps = 85/404 (21%)
Query: 32 DEHFQSLEVLTNRIL------NYSTNIPWEFQDD--PARSLAPLYFIYGPLLYFIKFFKL 83
+E F L+ + + + Y + P + PL + + F L
Sbjct: 22 EESFN-LQAMHDILYLRNNFTQYDHHD----YPGVVPRTFIGPLVVSIISAPFVLLFETL 76
Query: 84 NLTALQIWYIARLQI-SILSWIITDFCLYWMLPSKP--ERIKAIFFTSTSYITLVYQNHL 140
++ Y+ RL + +S + R+ T T + + Y
Sbjct: 77 SINKFWAQYVVRLVLAGAISVAWNSLR-QAVTKIYGVEVRLWFTAITITQFHFMFYMTRP 135
Query: 141 FSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTGVLISLGIFNRITFPAF 200
N ++L I ++ + L +
Sbjct: 136 LPNIFALPIVLFAIAYWLRDQHKP---------------FIICSGISILVFRSE----LA 176
Query: 201 LILPGWFVMKYVLKHYVSGLYL---VMGFFSTTALLILVDTILFGNINNVVAEPFNISSY 257
L L V+ + + L + A +LVD+ + + E
Sbjct: 177 LFLGILLVVSLLRRKVSIDGLLKVALPAGVCILAATVLVDSFFWRRLLWPEGEV------ 230
Query: 258 IIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFFVSKSYTKTT---PFLT 314
L YN + G P+ + +P+ +G L+ + L+
Sbjct: 231 -------LWYNTVLNKSSNWGTSPFLWYFYSALPRAMGASLVLVPIGVALEPRIRPLVLS 283
Query: 315 VISGLLFLSVIPHQELRFLIPLLPLACC--SFDFTLKWVQPWMLYTW-----------YI 361
+ +L S++PH+ELRF+I + P+ + W+ TW +
Sbjct: 284 ALLFVLLYSILPHKELRFIIYVFPVLNIAAACACQRIWMNS-AKSTWHSFLALACGAHLL 342
Query: 362 FNIFMSIL--------------MGKLH--QGGVVPVLDHIKSEA 389
N+F+++ + +LH + G V HI + A
Sbjct: 343 LNVFITLFLLVISGTNYPGGAALSRLHRLEAGTSNVSVHISNLA 386
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
lipid-linked oligosaccharides; Alg9p [Saccharomyces
cerevisiae]
sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
cerevisiae)
emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
Length = 555
Score = 213 bits (539), Expect = 5e-54
Identities = 68/360 (18%), Positives = 116/360 (31%), Gaps = 42/360 (11%)
Query: 4 INFNWRTFYLLTIVFRFVFTLSDSY---IHPDEHFQSLEVLTNRILNYSTNIPWEFQD-D 59
+N T LL ++F + ++ DE F E L + + WE+
Sbjct: 1 MNCKAVTISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQ-TWEYSPEY 59
Query: 60 PARSLAPLYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPE 119
RS A L Y L KF +L + ++I R + S+I+ E
Sbjct: 60 SIRSWAFLLPFYCILYPVNKFT--DLESHWNFFITRACLGFFSFIME-------FKLHRE 110
Query: 120 RIKAIFFTSTSYITLV--YQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKN 177
++ + + + F S+E L V +LL N
Sbjct: 111 IAGSLALQIANIWIIFQLFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGSTSNFT 170
Query: 178 KNLFYTGVLISLGIFNRITFPAFLILP--GWFVMKYVLKHYVS-GLYLVMGFFSTTALLI 234
K+L Y L F L LP ++ + + + + F T +I
Sbjct: 171 KSLAY----NFLASILGWPFVLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVI 226
Query: 235 LVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARY----ENLAQHGIHPYYTHILVNM 290
+ D+I +G + N L YN G+ P+Y + L +
Sbjct: 227 VTDSIFYGKLAP-------------VSWNILFYNVINASEESGPNIFGVEPWYYYPLNLL 273
Query: 291 PQILGPGLIFFVSKSY-TKTTPFLTVISG-LLFLSVIPHQELRFLIPLLPLACCSFDFTL 348
P L+ + + + P + + + PH+E RFL P+ L S
Sbjct: 274 LNFPLPVLVLAILGIFHLRLWPLWASLFTWIAVFTQQPHKEERFLYPIYGLITLSASIAF 333
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
(Swiss Prot accession number P38376)~cDNA EST yk549e12.3
comes from this gene~cDNA EST yk618d6.3 comes from this
gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
yk618d6.5 comes from>
Length = 653
Score = 208 bits (526), Expect = 2e-52
Identities = 66/393 (16%), Positives = 118/393 (29%), Gaps = 66/393 (16%)
Query: 11 FYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPLYF 69
+ + + R + DE + E L + WE+ RS +Y
Sbjct: 56 VFKMLLSIRISGAIWGIINDCDEVYNYWEPLHLFLYGEGFQ-TWEYSPVYAIRSYFYIYL 114
Query: 70 IYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAIFFTST 129
Y P F F T + ++ + RL I FCL + K I +
Sbjct: 115 HYIPASLFANLFG--DTKIVVFTLIRLT-------IGLFCLLGEYYAFDAICKKINIATG 165
Query: 130 SYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNL--NKNKNLFYTGVLI 187
+ L +FS+ + + +V S + N +T +
Sbjct: 166 RFFILF---SIFSSGM----------FLASTAFVPSSFCMAITFYILGAYLNENWTAGIF 212
Query: 188 SLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTA---LLILVDTILFGNI 244
+ + +P +L V +L + +++ + ++ D+ FG
Sbjct: 213 CVAFSTMVGWPFSAVLGLPIVADMLLLKGLRIRFILTSLVIGLCIGGVQVITDSHYFGKT 272
Query: 245 NNVVAEPFNISSYIIAPLNNLLYNARYE-NLAQHGIHPYYTHI--------LVNMPQILG 295
++APLN LYN + +G P +I +V G
Sbjct: 273 -------------VLAPLNIFLYNVVSGPGPSLYGEEPLSFYIKNLFNNWNIVIFAAPFG 319
Query: 296 -PGLIFFVSKSY------------TKTTPFLTVISG--LLFLSVIPHQELRFLIPLLPLA 340
P + + +K + L V + LL H+E RFL P+ P
Sbjct: 320 FPLSLAYFTKVWMSQDRNVALYQRFAPIILLAVTTAAWLLIFGSQAHKEERFLFPIYPFI 379
Query: 341 CCSFDFTLKWVQPWMLYTWYIFNIFMSILMGKL 373
L L + NI + +
Sbjct: 380 AFFAALALDATNRLCLKKLGMDNILSILFILCF 412
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
Length = 570
Score = 204 bits (516), Expect = 3e-51
Identities = 58/358 (16%), Positives = 109/358 (30%), Gaps = 61/358 (17%)
Query: 8 WRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD--DPARSLA 65
W ++ R++ S+ DE F E L + WE+ L
Sbjct: 46 WFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPLHYILYKSGFQ-TWEYSSNFALRSYLY 104
Query: 66 PLYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--A 123
++ L + ++++Y RL + ++S + + + +RI A
Sbjct: 105 ---ILFHELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYA 161
Query: 124 IFFTSTSYITLVYQNHLFSNSIET--LLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLF 181
+ + +S + L +LL +
Sbjct: 162 VAMLCLTSGCFFASTSFLPSSFSMYAISLSSGLLLFEK--------------------YA 201
Query: 182 YTGVLISLGIFNRITFPAFLILP-GWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTIL 240
+ +G+ F LP + + K + + +LVD
Sbjct: 202 MAVAVSVVGVILGWPFSILAFLPVVIYSLVKRFKQAFIAG--AVTTIFLLGVSLLVDYYY 259
Query: 241 FGNINNVVAEPFNISSYIIAPLNNLLYNARYEN-LAQHGIHPYYTHI--------LVNMP 291
+ + + LN L+YN +G +I +
Sbjct: 260 Y-------------KRWTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNGFNNFNFCFIL 306
Query: 292 QILGPGLIFFVSKSYTKTTPFLTVISG----LLFLSVIPHQELRFLIPLLPLACCSFD 345
+L + + + Y + L VIS L F+S+ PH+E RFL P+ PL C S
Sbjct: 307 AMLFVAIYPVIRRKYDR--ALLVVISPMYIWLAFMSLQPHKEERFLYPIYPLICVSAS 362
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
Length = 483
Score = 191 bits (482), Expect = 2e-47
Identities = 55/357 (15%), Positives = 107/357 (29%), Gaps = 64/357 (17%)
Query: 12 YLLTIVFRFVFTLSDSYIHP----DEHFQSLEVLTNRIL------NYSTNIPWEFQD-DP 60
+ I P +E F L+ + + Y + EF P
Sbjct: 11 SWPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHH---EFPGVVP 66
Query: 61 ARSLAPLYFIY--GPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKP 118
L PL P++Y + + ++ I R + + I + L + +
Sbjct: 67 RTFLGPLVIAAFSSPVVYVLSLLE--VSKFYSQLIVRGVLGL-GVISGLWTLQKEVRQQF 123
Query: 119 ERIKAIFFT---STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLN 175
A+ F +T + + Y N + ++L + R+
Sbjct: 124 GATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRRWA------------ 171
Query: 176 KNKNLFYTGVLISLGI-----FNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTT 230
+ + +G + + VL+H + L +G
Sbjct: 172 ---LFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLG----- 223
Query: 231 ALLILVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNM 290
L + VD+ + + L YN + G P + +
Sbjct: 224 -LTVAVDSYFWRYLVWPEGVV-------------LGYNTVLNKSSNWGTSPLLWYFYSAL 269
Query: 291 PQILGPGLIFFVSKSYTKTTPFLT--VISGLLFLSVIPHQELRFLIPLLPLACCSFD 345
P+ LG L+F + + T L + + S++PH+ELRF+I P+
Sbjct: 270 PRGLGCSLLFIPLGAVDRRTYALALPSLGFVALYSLLPHKELRFIIYTFPVLNIMAA 326
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
Length = 509
Score = 190 bits (480), Expect = 4e-47
Identities = 59/350 (16%), Positives = 111/350 (30%), Gaps = 46/350 (13%)
Query: 10 TFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARSLAPLYF 69
LL + R Y HPDE FQ LE YS IPWE++ L P+
Sbjct: 25 LITLLALCLRMTAIFPIGYYHPDEIFQYLEQAHRLAFGYSV-IPWEYRYGMRGGLVPVLL 83
Query: 70 IYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPER-----IKAI 124
+ I +N + W + ++LS + ++ A+
Sbjct: 84 AAAMKMGDI----MNTQSFLYWVLPHAITALLSLGV----IWSAYKLGRLHSFFTGCLAM 135
Query: 125 FFTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFYTG 184
F +T Y +++ H S S+ + + + + + +
Sbjct: 136 FVAATWYEIVLFAAHPLSESLSFAAFMPAAYYL----------IAEEKKKSSLILSGFLM 185
Query: 185 VLISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNI 244
L +L F I F+ L F ++ ++ + + +G ++L I G
Sbjct: 186 GLSALLRFQYIPSILFITL---FTLRINVRQWGYFILGGLGAVFISSLS----DIFIGEY 238
Query: 245 NNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHIL---VNMPQILGPGLIFF 301
+ N+ N + +G P Y++ N I
Sbjct: 239 PLLWL------------FKNIQQNLIFHRAEDYGTAPIYSYFFDIWTNWKWFSLILPIPI 286
Query: 302 VSKSYTKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSFDFTLKWV 351
+ +Y F T + L+F ++ H+E RF+ + +
Sbjct: 287 LVAAYRYPALFGTALVNLIFHMLVSHKEYRFIFLSSGIFIILAAIGSALL 336
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
Length = 492
Score = 176 bits (444), Expect = 6e-43
Identities = 49/377 (12%), Positives = 113/377 (28%), Gaps = 63/377 (16%)
Query: 20 FVFTLSDSYIHP----DEHFQSLEVLTNRILNYSTNIPWEFQDD---------PARSLAP 66
+ T+ + P +E F ++ + + ++P + P + P
Sbjct: 9 IIVTIIHIILAPGTKVEESFN-VQATHDLMF----HLPTNLSNYDHSQFPGVVPRTFIGP 63
Query: 67 --LYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKAI 124
L + P+ + +F+ + + + R + +++ + + +
Sbjct: 64 ISLAILSSPMSFIFRFWA--IPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFGRETAMY 121
Query: 125 --FFTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNLFY 182
T + + Y + N+ +L+++ + + RY + + L
Sbjct: 122 LRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYESAVRYATASVILFRCELVL 181
Query: 183 TGVLISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMG---FFSTTALLILVDTI 239
I LG LK + + +G A+ I +D+
Sbjct: 182 LYGPIFLGYMI----------------SGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSY 225
Query: 240 LFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILGPGLI 299
+G E +N ++G P+ + +P+ L +
Sbjct: 226 FWGRPLWPEGEVMF-------------FNVVENRSHEYGTQPFLWYFYSALPRCLLTTTL 272
Query: 300 FFVSKS---YTKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACC----SFDFTLKWVQ 352
L + + S +PH+ELRF+I +LP+ C L
Sbjct: 273 LVPLGLLVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRH 332
Query: 353 PWMLYTWYIFNIFMSIL 369
F + + +L
Sbjct: 333 KSFFRMILFFGVILHLL 349
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
Length = 369
Score = 176 bits (443), Expect = 8e-43
Identities = 44/324 (13%), Positives = 97/324 (29%), Gaps = 45/324 (13%)
Query: 60 PARSLAP--LYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSK 117
P + P L + P+ + +F+ + + + R + +++ + + +
Sbjct: 15 PRTFIGPISLAILSSPMSFIFRFWA--IPKMWQLLLIRATLGLMNAMAFLYFARSVNRKF 72
Query: 118 PERIKAI--FFTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLN 175
T + + Y + N+ +L+++ + + RY + +
Sbjct: 73 GRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYESAVRYATASVIL 132
Query: 176 KNKNLFYTGVLISLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMG---FFSTTAL 232
L I LG LK + + +G A+
Sbjct: 133 FRCELVLLYGPIFLGYMI----------------SGRLKVFGFDGAIAIGVRIAAMCLAV 176
Query: 233 LILVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQ 292
I +D+ +G E +N ++G P+ + +P+
Sbjct: 177 SIPIDSYFWGRPLWPEGEVMF-------------FNVVENRSHEYGTQPFLWYFYSALPR 223
Query: 293 ILGPGLIFFVSKS---YTKTTPFLTVISGLLFLSVIPHQELRFLIPLLPLACC----SFD 345
L + L + + S +PH+ELRF+I +LP+ C
Sbjct: 224 CLLTTTLLVPLGLLVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCA 283
Query: 346 FTLKWVQPWMLYTWYIFNIFMSIL 369
L F + + +L
Sbjct: 284 RMLINRHKSFFRMILFFGVILHLL 307
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
Length = 488
Score = 172 bits (432), Expect = 2e-41
Identities = 52/367 (14%), Positives = 109/367 (29%), Gaps = 60/367 (16%)
Query: 14 LTIVFRFVFTLSDSYIHP----DEHFQSLEVLTNRILNYSTNIPW---EFQD-DPARSLA 65
L + I P +E F L+ + + ++ + EF P L
Sbjct: 12 LLLGLLVAVATVHLVICPYTKVEESFN-LQATHDLLYHWQDLEQYDHLEFPGVVPRTFLG 70
Query: 66 PLYFI--YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKA 123
P+ P +Y + ++ + I R + + I + L + + A
Sbjct: 71 PVVIAVFSSPAVYVLSLLEM--SKFYSQLIVRGVLGL-GVIFGLWTLQKEVRRHFGAMVA 127
Query: 124 IFFT---STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNL 180
F + + + Y N + ++L+ + +
Sbjct: 128 TMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWA---------------RF 172
Query: 181 FYTGVLISLGIFNRITFPAFLILP-----GWFVMKYVLKHYVSGLYLVMGFFSTTALLIL 235
+ + + L+L + L+H V L +G L +
Sbjct: 173 IWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLG------LTVA 226
Query: 236 VDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILG 295
VD+ + + + L YN + G P + +P+ LG
Sbjct: 227 VDSYFWRQLTWPEGKV-------------LWYNTVLNKSSNWGTSPLLWYFYSALPRGLG 273
Query: 296 PGLIFFVSKSYTKT--TPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSF--DFTLKWV 351
L+F + P + + + S++PH+ELRF+I P+ + +
Sbjct: 274 CSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLN 333
Query: 352 QPWMLYT 358
+
Sbjct: 334 NYKKSWL 340
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
mannosyltransferase [Homo sapiens]
Length = 488
Score = 171 bits (431), Expect = 2e-41
Identities = 53/367 (14%), Positives = 110/367 (29%), Gaps = 60/367 (16%)
Query: 14 LTIVFRFVFTLSDSYIHP----DEHFQSLEVLTNRILNYSTNIPW---EFQD-DPARSLA 65
L + I P +E F L+ + + ++ + EF P L
Sbjct: 12 LLLGLLVAVATVHLVICPYTKVEESFN-LQATHDLLYHWQDLEQYDHLEFPGVVPRTFLG 70
Query: 66 PLYFI--YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIKA 123
P+ P +Y + ++ + I R + + I + L + + A
Sbjct: 71 PVVIAVFSSPAVYVLSLLEM--SKFYSQLIVRGVLGL-GVIFGLWTLQKEVRRHFGAMVA 127
Query: 124 IFFT---STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNL 180
F + + +VY N + ++L+ + +
Sbjct: 128 TMFCWVTAMQFHLMVYCTRTLPNVLALPVVLLALAAWLRHEWA---------------RF 172
Query: 181 FYTGVLISLGIFNRITFPAFLILP-----GWFVMKYVLKHYVSGLYLVMGFFSTTALLIL 235
+ + + L+L + L+H V L +G L +
Sbjct: 173 IWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLG------LTVA 226
Query: 236 VDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQILG 295
VD+ + + + L YN + G P + +P+ LG
Sbjct: 227 VDSYFWRQLTWPEGKV-------------LWYNTVLNKSSNWGTSPLLWYFYSALPRGLG 273
Query: 296 PGLIFFVSKSYTKT--TPFLTVISGLLFLSVIPHQELRFLIPLLPLACCSF--DFTLKWV 351
L+F + P + + + S++PH+ELRF+I P+ + +
Sbjct: 274 CSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLN 333
Query: 352 QPWMLYT 358
+
Sbjct: 334 NYKKSWL 340
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
chromosome I precursor [Leishmania major]
Length = 822
Score = 165 bits (416), Expect = 1e-39
Identities = 41/348 (11%), Positives = 91/348 (25%), Gaps = 79/348 (22%)
Query: 9 RTFYLLTIVFRFVFTLSDSYI--------HPDEHFQSLEVLTNRILNYSTNIPWEF-QDD 59
R L + F+ Y DE F +E + + WE
Sbjct: 4 RITCYLKMAAAFLLLSLTHYFASSFLPISDCDETFNFIEPIHYLLYGSGKQ-TWEVCSRF 62
Query: 60 PARSLAPLYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWM------ 113
RS L+ P++ L +++++++ R+ + + F + +
Sbjct: 63 ALRSWLFLWIHAWPVVLIRGAASL--SSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSG 120
Query: 114 -------------LPSKPERIKAI---FFTSTSYITLVYQNHLFSNSIETLLLL-----V 152
P + + + F +++ L S + + LL
Sbjct: 121 KAAAVALLLLLANYPIQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLSRVGDRP 180
Query: 153 TILLIDDLRYVQESKDQDVQNLNK-----------------NKNLFYTGV---LISLGIF 192
T + V ++ G L +
Sbjct: 181 TQNTMPAAAAGTAQLSMMVPPSPSSAPTLHSSSASPPSAPPRHLCWFIGAALCFSVLAVV 240
Query: 193 NRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTILFGNINNVVAEPF 252
F A + + +L+ V L +G + V A+
Sbjct: 241 TGWPFAALISALVGLDL--LLRFPVRTLACTLGSLLVACAAVFV------------ADVR 286
Query: 253 NISSYIIAPLNNLLYNARYE---NLAQHGIHPYYTH---ILVNMPQIL 294
+ ++ N ++YN G+ P + +++N +
Sbjct: 287 YYCRWTLSSWNVVMYNGFGGSGRGPELFGVEPIFFFWKNLMLNFHLMF 334
Score = 38.8 bits (90), Expect = 0.21
Identities = 13/62 (20%), Positives = 18/62 (28%), Gaps = 4/62 (6%)
Query: 291 PQILGPGLIFFVSKSYTKTTPFLTVISGLLFLSVI----PHQELRFLIPLLPLACCSFDF 346
P+ P S L I + H+E RF+ P P +
Sbjct: 414 PRGPLPAATTAAVGSRLSRERELLHIMPFFVWFLFWMSIAHKEERFMSPAYPFMLLAATR 473
Query: 347 TL 348
TL
Sbjct: 474 TL 475
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
(Schizosaccharomyces pombe)
emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
architecture [Schizosaccharomyces pombe]
Length = 547
Score = 150 bits (377), Expect = 5e-35
Identities = 61/353 (17%), Positives = 110/353 (30%), Gaps = 56/353 (15%)
Query: 11 FYLLTIVFRFVFTLS-DSYIHP----DEHFQSLEVLTNR-ILNYSTNIPW---EFQDDPA 61
V + SY P +E F +++ + + + + + EF
Sbjct: 7 ICWYLANILLVTCIGYYSYKTPFTKVEESF-AMQAIHDIQTYRWDLSKVYDHLEFPGAVK 65
Query: 62 RSLAPLYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERI 121
RS P FI L Y +F + L AR I LSW + +
Sbjct: 66 RSFIPSLFIAV-LSYIPSWF---VNPLL---AARWTIGYLSWESMNSVSCSISKRFGTLS 118
Query: 122 KAIF--FTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKN 179
A+F F+ + + Y + SN + ++ L+ Y
Sbjct: 119 GALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKNNY-----------YGSISI 167
Query: 180 LFYTGVLI-SLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDT 238
L + ++ S + L+L + +L +S +G L+D+
Sbjct: 168 LVFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASF------LIDS 221
Query: 239 ILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQIL---G 295
+G E L+N + G P+Y + V +P +
Sbjct: 222 YFWGAWCWPELEA-------------FLFNVVEGKSSDWGTSPFYYYF-VRLPWLFLNPT 267
Query: 296 PGLIFFVSKSYTKTTPFLTV--ISGLLFLSVIPHQELRFLIPLLPLACCSFDF 346
L +S Y K L + + S + H+E RF+I +P +
Sbjct: 268 TLLFLLISFVYIKPARLLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAASAI 320
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
Length = 283
Score = 140 bits (350), Expect = 8e-32
Identities = 35/180 (19%), Positives = 71/180 (39%), Gaps = 28/180 (15%)
Query: 222 LVMGFFSTTALLI-LVDTIL----------------FGNINNVVAEPFNISSYIIAPLNN 264
L+ + + LV + +G + ++ S+ L
Sbjct: 71 LLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPAL-- 128
Query: 265 LLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFFVSKS------YTKTTPFLTVISG 318
+ +N A G+HP+Y +I+ +P +L +I + PF I+
Sbjct: 129 IAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITY 188
Query: 319 LLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPW---MLYTWYIFNIFMSILMGKLHQ 375
++ S++PH+E RFL+P++PL C + ++ W + NI +++ + HQ
Sbjct: 189 IIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRGSAMAVMIAINIGIALFTSRYHQ 248
Score = 97.2 bits (240), Expect = 5e-19
Identities = 19/105 (18%), Positives = 37/105 (35%), Gaps = 4/105 (3%)
Query: 1 MIKINFNWRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDP 60
++++ R L + L S+ PDE +QS EV + + + WE++
Sbjct: 62 VLRMRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGH-LSWEWRHSL 120
Query: 61 ARSLAPLYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWII 105
P + + F WYI ++L+ +
Sbjct: 121 RSFFHPALIAFNVVQGGSALFG---VHPWYWYIVSGIPAVLTVQM 162
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
Length = 198
Score = 138 bits (345), Expect = 3e-31
Identities = 21/135 (15%), Positives = 42/135 (30%), Gaps = 7/135 (5%)
Query: 12 YLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQD-DPARSLAPLYFI 70
+ + R L + DE F E I WE+ RS A L
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGEGFQ-TWEYSPAYAIRSYAYLLLH 120
Query: 71 YGPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKPERIK--AIFFTS 128
P + + L + ++Y R ++ +S I + + + + F
Sbjct: 121 AWPAAFHARI--LQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLV 178
Query: 129 TSYITLVYQNHLFSN 143
S + + ++ +
Sbjct: 179 LS-TGMFCSSSVYPS 192
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
[Caenorhabditis elegans]
Length = 232
Score = 132 bits (330), Expect = 1e-29
Identities = 35/180 (19%), Positives = 71/180 (39%), Gaps = 28/180 (15%)
Query: 222 LVMGFFSTTALLI-LVDTIL----------------FGNINNVVAEPFNISSYIIAPLNN 264
L+ + + LV + +G + ++ S+ L
Sbjct: 7 LLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPAL-- 64
Query: 265 LLYNARYENLAQHGIHPYYTHILVNMPQILGPGLIFFVSKS------YTKTTPFLTVISG 318
+ +N A G+HP+Y +I+ +P +L +I + PF I+
Sbjct: 65 IAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITY 124
Query: 319 LLFLSVIPHQELRFLIPLLPLACCSFDFTLKWVQPW---MLYTWYIFNIFMSILMGKLHQ 375
++ S++PH+E RFL+P++PL C + ++ W + NI +++ + HQ
Sbjct: 125 IIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRGSAMAVMIAINIGIALFTSRYHQ 184
Score = 88.7 bits (218), Expect = 2e-16
Identities = 19/102 (18%), Positives = 34/102 (32%), Gaps = 4/102 (3%)
Query: 4 INFNWRTFYLLTIVFRFVFTLSDSYIHPDEHFQSLEVLTNRILNYSTNIPWEFQDDPARS 63
+ R L + L S+ PDE +QS EV + + + WE++
Sbjct: 1 MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGH-LSWEWRHSLRSF 59
Query: 64 LAPLYFIYGPLLYFIKFFKLNLTALQIWYIARLQISILSWII 105
P + + F WYI ++L+ +
Sbjct: 60 FHPALIAFNVVQGGSALFG---VHPWYWYIVSGIPAVLTVQM 98
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
cerevisiae)
emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
Length = 551
Score = 130 bits (326), Expect = 4e-29
Identities = 36/317 (11%), Positives = 89/317 (27%), Gaps = 61/317 (19%)
Query: 60 PARSLAPLYFIYGP---LLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPS 116
P + + L T++ + + R + + + + + +
Sbjct: 59 PRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDM 118
Query: 117 KPER--------------------IKAIFFTSTSYITLVYQNHLFSN-SIETLLLLVTIL 155
E + F S+ + Y N + L V +
Sbjct: 119 FDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALG 178
Query: 156 LIDDLRYVQESKDQDVQNLNKNKNLFYTGVLISLGIFNRITFPAFLILPGWFVMKYVLKH 215
+ L + + L+++ ++ + I F + +
Sbjct: 179 WVL---------------LGRYNAAIFLSALVAIVFRLEVSALSAGIA--LFSVIFKKIS 221
Query: 216 YVSGL-YLVMGFFSTTALLILVDTILFGNINNVVAEPFNISSYIIAPLNNLLYNARYENL 274
+ + + G +A+ I VD+ + + + ++ L+N
Sbjct: 222 LFDAIKFGIFGLGLGSAISITVDSYFWQE-------------WCLPEVDGFLFNVVAGYA 268
Query: 275 AQHGIHPYYTHILVNMPQILGP--GLIFFVSKSYTKTTPF----LTVISGLLFLSVIPHQ 328
++ G+ P + + + P L+ L + ++ LS PH+
Sbjct: 269 SKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHK 328
Query: 329 ELRFLIPLLPLACCSFD 345
E RF+I +P
Sbjct: 329 EWRFIIYAVPSIMLLGA 345
>gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protein MGC3136 [Mus musculus]
Length = 385
Score = 105 bits (261), Expect = 2e-21
Identities = 33/246 (13%), Positives = 70/246 (28%), Gaps = 45/246 (18%)
Query: 12 YLLTIVFRFVFTLSDSYIHP----DEHFQSLEVLTNRIL------NYSTNIPWEFQD-DP 60
+ I P +E F L+ + + Y + EF P
Sbjct: 11 SWPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHH---EFPGVVP 66
Query: 61 ARSLAPLYFIY--GPLLYFIKFFKLNLTALQIWYIARLQISILSWIITDFCLYWMLPSKP 118
L PL P++Y + + ++ I R + + I + L + +
Sbjct: 67 RTFLGPLVIAAFSSPVVYVLSLLE--VSKFYSQLIVRGVLGL-GVISGLWTLQKEVRQQF 123
Query: 119 ERIKAIFFT---STSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLN 175
A+ F +T + + Y N + ++L + R+
Sbjct: 124 GATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRRWA------------ 171
Query: 176 KNKNLFYTGVLISLGI-----FNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTT 230
+ + +G + + VL+H + L +G
Sbjct: 172 ---LFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLG--KLA 226
Query: 231 ALLILV 236
+L+ L+
Sbjct: 227 SLVCLL 232
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
Length = 278
Score = 104 bits (259), Expect = 3e-21
Identities = 33/148 (22%), Positives = 57/148 (38%), Gaps = 27/148 (18%)
Query: 289 NMPQILGPGLIFFVSKSYTKTT----------PF----LTVISGLLFLSVIPHQELRFLI 334
+P +LG + F + + PF LT++ LL S +PH+E RF+
Sbjct: 1 ALPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIF 60
Query: 335 PLLPLACC--SFDFTLKWVQPWM--------LYTWYIFNIFMSILMGKLHQGGVVPVLDH 384
PL PL SF W L+ ++F+++L+ H+ G + V+
Sbjct: 61 PLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVMKF 120
Query: 385 IKSEA---SVQVWWRTYTPPSWILGSNS 409
+ E S+ ++ P S
Sbjct: 121 LHEEPEIDSLGFIMPCHSTPGQSYLHRS 148
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
Length = 197
Score = 101 bits (252), Expect = 2e-20
Identities = 36/223 (16%), Positives = 69/223 (30%), Gaps = 37/223 (16%)
Query: 121 IKAIFFTSTSYITLVYQNHLFSNSIETLLLLVTILLIDDLRYVQESKDQDVQNLNKNKNL 180
I F+ + + Y + SN + ++ L+ Y L
Sbjct: 6 ALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKNNY-----------YGSISIL 54
Query: 181 FYTGVLI-SLGIFNRITFPAFLILPGWFVMKYVLKHYVSGLYLVMGFFSTTALLILVDTI 239
+ ++ S + L+L + +L +S +G L+D+
Sbjct: 55 VFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASF------LIDSY 108
Query: 240 LFGNINNVVAEPFNISSYIIAPLNNLLYNARYENLAQHGIHPYYTHILVNMPQIL---GP 296
+G E L+N + G P+Y + V +P +
Sbjct: 109 FWGAWCWPELEA-------------FLFNVVEGKSSDWGTSPFYYYF-VRLPWLFLNPTT 154
Query: 297 GLIFFVSKSYTKTTPFLTV--ISGLLFLSVIPHQELRFLIPLL 337
L +S Y K L + + S + H+E RF+I +
Sbjct: 155 LLFLLISFVYIKPARLLIYVPLFFIFVYSFLGHKEWRFIIYSI 197
CPU time: 165.46 user secs. 2.72 sys. secs 168.18 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.317 0.177 0.503
Gapped
Lambda K H
0.270 0.0620 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 363389324
Number of Sequences: 887402
Number of extensions: 20597895
Number of successful extensions: 96743
Number of sequences better than 10.0: 1337
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 1328
Number of HSP's that attempted gapping in prelim test: 94704
Number of HSP's gapped (non-prelim): 2533
length of query: 498
length of database: 277,845,442
effective HSP length: 51
effective length of query: 447
effective length of database: 232,587,940
effective search space: 103966809180
effective search space used: 103966809180
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 76 (33.6 bits)
