Sequences with E-value BETTER than threshold (0.002)
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 594 e-168
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 592 e-168
ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 386 e-106
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 375 e-102
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 374 e-102
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 373 e-102
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 350 2e-95
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 318 2e-85
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 316 6e-85
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 315 1e-84
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 314 2e-84
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 314 3e-84
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 312 1e-83
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 311 3e-83
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 299 1e-79
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 293 3e-78
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 278 2e-73
emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus mus... 269 6e-71
gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melano... 267 3e-70
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 266 7e-70
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 265 1e-69
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 264 3e-69
ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo ... 253 7e-66
emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-... 252 1e-65
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 244 3e-63
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 244 3e-63
ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans] ... 241 2e-62
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 233 5e-60
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 230 5e-59
pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans 229 7e-59
gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 229 8e-59
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 229 1e-58
pir||T39659 cell wall biosynthesis protein N3265 homolog - fissi... 214 3e-54
ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Sacch... 202 1e-50
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 201 3e-50
gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan ... 201 3e-50
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 173 4e-42
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 148 3e-34
gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protei... 134 3e-30
dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharom... 130 5e-29
pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans 128 3e-28
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 123 7e-27
ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]... 121 2e-26
Sequences with E-value WORSE than threshold
ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. ... 45 0.004
ref|NP_069450.1| (NC_000917) conserved hypothetical protein [Arc... 35 4.3
Alignments
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
most likely an alpha 1,2 mannosyltransferase utilized
for addition of the fourth, side-branching mannose onto
the GPI core structure.; Smp3p [Saccharomyces
cerevisiae]
sp|Q04174|SMP3_YEAST SMP3 PROTEIN
pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
Length = 516
Score = 594 bits (1517), Expect = e-168
Identities = 516/516 (100%), Positives = 516/516 (100%)
Query: 1 MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS
Sbjct: 1 MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
Query: 61 YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120
YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ
Sbjct: 61 YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120
Query: 121 FMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLI 180
FMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLI
Sbjct: 121 FMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLI 180
Query: 181 FSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK 240
FSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK
Sbjct: 181 FSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK 240
Query: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYA 300
GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYA
Sbjct: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYA 300
Query: 301 IISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM 360
IISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM
Sbjct: 301 IISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM 360
Query: 361 GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDGIESID 420
GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDGIESID
Sbjct: 361 GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDGIESID 420
Query: 421 EVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPNSMTSELKKLKRDGTIN 480
EVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPNSMTSELKKLKRDGTIN
Sbjct: 421 EVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPNSMTSELKKLKRDGTIN 480
Query: 481 LIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSIELL 516
LIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSIELL
Sbjct: 481 LIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSIELL 516
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
Length = 516
Score = 592 bits (1512), Expect = e-168
Identities = 511/516 (99%), Positives = 514/516 (99%)
Query: 1 MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS
Sbjct: 1 MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
Query: 61 YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120
YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ
Sbjct: 61 YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120
Query: 121 FMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLI 180
F++KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVN KNIQR NFKNSVILGLI
Sbjct: 121 FIKKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNGKNIQRRNFKNSVILGLI 180
Query: 181 FSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK 240
FSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK
Sbjct: 181 FSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK 240
Query: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYA 300
GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQI+GPVLLLAIFSGYKLDKLSTYA
Sbjct: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQILGPVLLLAIFSGYKLDKLSTYA 300
Query: 301 IISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM 360
IISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM
Sbjct: 301 IISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM 360
Query: 361 GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDGIESID 420
GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDGIESID
Sbjct: 361 GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSLINTQDGIESID 420
Query: 421 EVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPNSMTSELKKLKRDGTIN 480
EVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPNSMTSELKKLKRDGTIN
Sbjct: 421 EVAFSVGNHHVIDLKGCDLPLLTETIRRLRLNGSITPLTLVTPNSMTSELKKLKRDGTIN 480
Query: 481 LIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSIELL 516
LIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSIELL
Sbjct: 481 LIPKRNYLFHLDLDHLDFNDFTTFKPGLTVYSIELL 516
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase -like protein [Arabidopsis
thaliana]
gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
Length = 548
Score = 386 bits (983), Expect = e-106
Identities = 87/437 (19%), Positives = 161/437 (35%), Gaps = 48/437 (10%)
Query: 5 QWWLYLVYAIGLMLCLGPS-YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
+ A ++ L Y +PDEH+Q +E+ A + + G + WE+ K RSY
Sbjct: 39 RRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEV-AHRTIFGYGYMTWEW--KRGIRSYLH 95
Query: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQ 123
+L + L+ +L+ D P +++ + RL + + +L V
Sbjct: 96 PML-FAFLYKLLQVTGL--DTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWS 152
Query: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSV--ILGL-I 180
+ ++ + TFSN +ET+ I L I+ S+ V GL I
Sbjct: 153 LFCQMANWFIFFCLNRTFSNCLETVLTIMGLYY------WPCIRDSSIDYPVNRKWGLVI 206
Query: 181 FSFGVFNRVT-FPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
+ R T ++++ L LF +V + ++ + S L+D +Y +
Sbjct: 207 AALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIG-SLVLGFTCLLDRLMYGS- 264
Query: 240 KGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKL-ST 298
+VI PLN LK+N +G HP + + ++ +I K +
Sbjct: 265 --WVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLS 322
Query: 299 YAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPL----------------------S 336
I+ L S H+E RF++P++P+ + + +
Sbjct: 323 ALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQN 382
Query: 337 STLVNKKIFKGTWLL--FNIIMAFIMGISHQAGIIQFLGDYFHFR--TEQMGVHIWWKTY 392
T + K+ + L NI MA M + HQ G + + +
Sbjct: 383 HTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCH 442
Query: 393 SPPTWMYMSNNLTVSSL 409
S P + + N+ + L
Sbjct: 443 STPYYSTLHRNIPMQFL 459
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
Length = 554
Score = 375 bits (954), Expect = e-102
Identities = 87/418 (20%), Positives = 165/418 (38%), Gaps = 34/418 (8%)
Query: 5 QWWLYLVYAIGLMLCLGPSY-IHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
+ L A+ ++ C PDE++Q +E+ + G + WE+ + RSY
Sbjct: 61 IYLLLFTLALRILNCFLVQTSFVPDEYWQSLEVS-HHMVFNYGYLTWEWTERL--RSYTY 117
Query: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQ 123
L++ ++ IL +D+ L+++ RL ++ + L + + E + V
Sbjct: 118 P-LIFASIYKILHLLG--KDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWV 174
Query: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSF 183
L S+ TW T T +N++ET+ I L ++ S NSV + +
Sbjct: 175 FFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYY-------PLEGSKSMNSVKYSSLVAL 227
Query: 184 GVFNRVTFPAFIFLPCLILFWKF----YRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
R T L +LF F ++ L + F + L ++ID +
Sbjct: 228 AFIIRPTAV---ILWTPLLFRHFCQEPRKLDLILHHFLPVGFV-TLSLSLMIDRIFF--- 280
Query: 240 KGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVG---PVLLLAIFSGYKLDKL 296
+ + N LK+N+ +G HP + + P I+G P + + K ++
Sbjct: 281 GQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRI 340
Query: 297 STYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIM 356
++ LL S H+E RF+ P++P + ++ L+ KK L N+ +
Sbjct: 341 LLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYS-LTHLKTWKKPALSFLFLSNLFL 399
Query: 357 AFIMGISHQAGIIQFLGD-----YFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSL 409
A G+ HQ G + + Y + + I +S P + ++ L + L
Sbjct: 400 ALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFL 457
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
GPI-anchor biosynthesis [Mus musculus]
dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
Length = 542
Score = 374 bits (952), Expect = e-102
Identities = 84/417 (20%), Positives = 164/417 (39%), Gaps = 34/417 (8%)
Query: 6 WWLYLVYAIGLMLCLGPSY-IHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPL 64
+ + A+ ++ C PDE++Q +E+ A + + G + WE+ + +Y
Sbjct: 51 YLVLFTIALRILNCFLVQTSFVPDEYWQSLEV-AHRMVFSYGYLTWEWTERLRGYTYP-- 107
Query: 65 LLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQK 124
L++ ++ +L +D+ +++ RL ++ + L L + E + V
Sbjct: 108 -LIFASIYKVLHLLG--KDSVQFLIWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVF 164
Query: 125 SLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFG 184
L S+ TW T T +N++ET L ++ S NS+ L+ +
Sbjct: 165 LCQLCSWFTWYCCTRTLTNTMETSLTALALFYY-------PLEGSRSVNSIKYSLLVALA 217
Query: 185 VFNRVTFPAFIFLPCLILFWKF----YRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGK 240
R T +LF F ++H L + F + L ++ID +
Sbjct: 218 CVVRPTAL---IPWVPLLFRHFYQEQRKLHLTLHHFLPVGF-ITFSLSLIIDRIFF---G 270
Query: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVG---PVLLLAIFSGYKLDKLS 297
+ + LN LK+N+ +G HP + +L P ++G P + F + +
Sbjct: 271 QWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLHIL 330
Query: 298 TYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMA 357
++ LL S H+E RF+ P++P + ++ +K LL N+ +A
Sbjct: 331 LLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLA-HLKTWRKAALSFLLLSNVPLA 389
Query: 358 FIMGISHQAGIIQFLGDY-----FHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSL 409
F G+ HQ G + + V I +S P + ++ L++ L
Sbjct: 390 FYTGLVHQRGTLDVMNHIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCPLSMRFL 446
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
(EC 2.4.1.130) PIGB - human
dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
Length = 554
Score = 373 bits (949), Expect = e-102
Identities = 87/418 (20%), Positives = 165/418 (38%), Gaps = 34/418 (8%)
Query: 5 QWWLYLVYAIGLMLCLGPSY-IHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
+ L A+ ++ C PDE++Q +E+ + G + WE+ + RSY
Sbjct: 61 IYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVS-HHMVFNYGYLTWEWTERL--RSYTY 117
Query: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQ 123
L++ ++ IL +D+ L+++ RL ++ + L + + E + V
Sbjct: 118 P-LIFASIYKILHLLG--KDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWV 174
Query: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSF 183
L S+ TW T T +N++ET+ I L ++ S NSV + +
Sbjct: 175 FFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYY-------PLEGSKSMNSVKYSSLVAL 227
Query: 184 GVFNRVTFPAFIFLPCLILFWKF----YRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
R T L +LF F ++ L + F + L ++ID +
Sbjct: 228 AFIIRPTAV---ILWTPLLFRHFCQEPRKLDLILHHFLPVGFV-TLSLSLMIDRIFF--- 280
Query: 240 KGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVG---PVLLLAIFSGYKLDKL 296
+ + N LK+N+ +G HP + + P I+G P + + K ++
Sbjct: 281 GQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRI 340
Query: 297 STYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIM 356
++ LL S H+E RF+ P++P + ++ L+ KK L N+ +
Sbjct: 341 LLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYS-LTHLKTWKKPALSFLFLSNLFL 399
Query: 357 AFIMGISHQAGIIQFLGD-----YFHFRTEQMGVHIWWKTYSPPTWMYMSNNLTVSSL 409
A G+ HQ G + + Y + + I +S P + ++ L + L
Sbjct: 400 ALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFL 457
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein - Arabidopsis
thaliana
emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein [Arabidopsis
thaliana]
Length = 498
Score = 350 bits (891), Expect = 2e-95
Identities = 80/437 (18%), Positives = 150/437 (34%), Gaps = 71/437 (16%)
Query: 5 QWWLYLVYAIGLMLCLGPS-YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
+ A ++ L Y +PDEH+Q +E+ A + + G + WE+ K RSY
Sbjct: 39 RRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEV-AHRTIFGYGYMTWEW--KRGIRSYLH 95
Query: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQ 123
+L + L+ +L+ D P +++ + RL + + +L V
Sbjct: 96 PML-FAFLYKLLQVTGL--DTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWS 152
Query: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSV--ILGL-I 180
L + + I+ S+ V GL I
Sbjct: 153 TVLTIM-----------------------------GLYYWPCIRDSSIDYPVNRKWGLVI 183
Query: 181 FSFGVFNRVT-FPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
+ R T ++++ L LF +V + ++ + S L+D +Y +
Sbjct: 184 AALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIG-SLVLGFTCLLDRLMYGS- 241
Query: 240 KGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKL-ST 298
+VI PLN LK+N +G HP + + ++ +I K +
Sbjct: 242 --WVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLS 299
Query: 299 YAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPL----------------------S 336
I+ L S H+E RF++P++P+ + + +
Sbjct: 300 ALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQN 359
Query: 337 STLVNKKIFKGTWLL--FNIIMAFIMGISHQAGIIQFLGDYFHFR--TEQMGVHIWWKTY 392
T + K+ + L NI MA M + HQ G + + +
Sbjct: 360 HTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCH 419
Query: 393 SPPTWMYMSNNLTVSSL 409
S P + + N+ + L
Sbjct: 420 STPYYSTLHRNIPMQFL 436
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
Length = 611
Score = 318 bits (807), Expect = 2e-85
Identities = 77/420 (18%), Positives = 132/420 (31%), Gaps = 66/420 (15%)
Query: 8 LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLV 67
+ + L L + DE F E + +G WE+ +A RSY LLL
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEP-THYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
P +Q N L+ Y +R + +C + + + V M + L
Sbjct: 121 AWPAAFHAR---ILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
+ S + + +S + M + S V G I +
Sbjct: 178 VLSTGMFCSSSAFLPSSFCMYTTLIA------MTGWYMDKTSIAVLGVAAGAILGWPFSA 231
Query: 188 RVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPL 247
+ P L + WK + F L++ V+ID+ Y VI PL
Sbjct: 232 ALGLPIAFDLLVMKHRWKSF------FHWSLMALILFLVPVVVIDSYYY---GKLVIAPL 282
Query: 248 NNLKYNLN-VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGY--------------- 291
N + YN+ ++G P Y +L +N LA+
Sbjct: 283 NIVLYNVFTPHGPDLYGTEPWYFYL-INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQ 341
Query: 292 ---KLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTL--------- 339
L+ + + H+E RFL P+ PL+ LS+
Sbjct: 342 NLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL-CGAVALSALQKCYHFVFQR 400
Query: 340 --------VNKKIFKGTWLLFNII-----MAFIMGISHQAGIIQFLGDYFHFRTEQMGVH 386
+ + GT LF ++ +A G G + +++ T+ +H
Sbjct: 401 YRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGY---HGPLDLYPEFYRIATD-PTIH 456
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
Length = 611
Score = 316 bits (803), Expect = 6e-85
Identities = 76/420 (18%), Positives = 131/420 (31%), Gaps = 66/420 (15%)
Query: 8 LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLV 67
+ + L L + DE F E + +G WE+ +A RSY LLL
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEP-THYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
P +Q N L+ Y +R + +C + + + V M + L
Sbjct: 121 AWPAAFHAR---ILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
+ S + + +S + M + S V G I +
Sbjct: 178 VLSTGMFCSSSAFLPSSFCMYTTLIA------MTGWYMDKTSIAVLGVAAGAILGWPFSA 231
Query: 188 RVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPL 247
+ P L + WK + F L++ V+ID+ Y VI PL
Sbjct: 232 ALGLPIAFDLLVMKHRWKSF------FHWSLMALILFLVPVVVIDSYYY---GKLVIAPL 282
Query: 248 NNLKYNLN-VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGY--------------- 291
N + YN+ ++G P Y +L+ LA+
Sbjct: 283 NIVLYNVFTPHGPDLYGTEPWYFYLIKGF-LNFNVAFALALLVLPLTSLMEYLLQRFHVQ 341
Query: 292 ---KLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTL--------- 339
L+ + + H+E RFL P+ PL+ LS+
Sbjct: 342 NLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL-CGAVALSALQKCYHFVFQR 400
Query: 340 --------VNKKIFKGTWLLFNII-----MAFIMGISHQAGIIQFLGDYFHFRTEQMGVH 386
+ + GT LF ++ +A G G + +++ T+ +H
Sbjct: 401 YRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGY---HGPLDLYPEFYRIATD-PTIH 456
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
musculus]
Length = 611
Score = 315 bits (800), Expect = 1e-84
Identities = 79/421 (18%), Positives = 136/421 (31%), Gaps = 68/421 (16%)
Query: 8 LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLV 67
+ + L L + DE F E + KG WE+ +A RSY LLL
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEP-THYLIYGKGFQTWEYSPVYAIRSYAYLLLH 120
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
P +Q N L+ Y +R + +C + + + V M + L
Sbjct: 121 AWPAAFHAR---ILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
+ S + + +S + +T + I L + G
Sbjct: 178 VLSTGMFCSSSAFLPSSFCMYTTLIAMTGW------------YMDKTPIAVLGVAAGAIL 225
Query: 188 RVTFPAFIFLPCLILFWKFYRVHWKSF-SLLLLSFSFSSCLFVLIDTNIYNNGKGFVITP 246
F A + LP + + WKSF L++ + V+ID+ Y V+ P
Sbjct: 226 GWPFSAALGLP-IAFDLLARKHRWKSFLLWSLVALALFLVPVVVIDSYYY---GKLVVAP 281
Query: 247 LNNLKYNLN-VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGY-------------- 291
LN + YN+ ++G P Y +L +N LA+
Sbjct: 282 LNIVLYNVFTSHGPDLYGTEPWYFYL-INGFLNFNVAFALALLVLPLTFLMEYLLQRFHV 340
Query: 292 ----KLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTL-------- 339
L+ + + H+E RFL P+ PL+ LS+
Sbjct: 341 QNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL-CGAVALSALQKCYHFVFQ 399
Query: 340 ---------VNKKIFKGTWLLFNII-----MAFIMGISHQAGIIQFLGDYFHFRTEQMGV 385
+ + GT LF ++ +A G G + +++ T+ +
Sbjct: 400 RYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGY---HGPLDLYPEFYRIATD-PTI 455
Query: 386 H 386
H
Sbjct: 456 H 456
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
Length = 506
Score = 314 bits (798), Expect = 2e-84
Identities = 83/424 (19%), Positives = 152/424 (35%), Gaps = 44/424 (10%)
Query: 5 QWW-LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
+ + L +Y +PDEH+QC+E+ A + + G + WE+ K RSY
Sbjct: 46 RRVLALALAFRAANALLVRTYFNPDEHWQCLEV-AHRIVFGYGHLTWEW--KRGLRSYLH 102
Query: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQ 123
++ L+ IL D+P + + RL V +L V M+
Sbjct: 103 P-FIFAALYKILSLLHL--DSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHME 159
Query: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSF 183
L +T W +IE++ S ++ ++ + + + + LI +
Sbjct: 160 TVLTVTGLYYWFV-------AIESVKGNSVVS------KQQAASKQSPPSRKMALLIAAL 206
Query: 184 GVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLL---LSFSFSSCLFVLIDTNIYNNGK 240
R T + F ++ KS + L F + +D +Y +
Sbjct: 207 ACAIRPTS---AITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSR- 262
Query: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYK-LDKLSTY 299
+I PLN LK+NL +G H + + P ++ L +I K +
Sbjct: 263 --IIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAG 320
Query: 300 AIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLV------------NKKIFKG 347
I+ L+ S H+E RF++P++P + + + K+
Sbjct: 321 LIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVI 380
Query: 348 TWLLFNIIMAFIMGISHQAGIIQFLGDYFHFRTE--QMGVHIWWKTYSPPTWMYMSNNLT 405
+L N+ MA M + HQ G + + V +S P + + NL
Sbjct: 381 LLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLP 440
Query: 406 VSSL 409
+ L
Sbjct: 441 MRFL 444
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
Length = 618
Score = 314 bits (797), Expect = 3e-84
Identities = 77/427 (18%), Positives = 132/427 (30%), Gaps = 73/427 (17%)
Query: 8 LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLV 67
+ + L L + DE F E + +G WE+ +A RSY LLL
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEP-THYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
P +Q N L+ Y +R + +C + + + V M + L
Sbjct: 121 AWPAAFHAR---ILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
+ S + + +S + M + S V G I +
Sbjct: 178 VLSTGMFCSSSAFLPSSFCMYTTLIA------MTGWYMDKTSIAVLGVAAGAILGWPFSA 231
Query: 188 RVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPL 247
+ P L + WK + F L++ V+ID+ Y VI PL
Sbjct: 232 ALGLPIAFDLLVMKHRWKSF------FHWSLMALILFLVPVVVIDSYYY---GKLVIAPL 282
Query: 248 NNLKYNLN-VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGY--------------- 291
N + YN+ ++G P Y +L +N LA+
Sbjct: 283 NIVLYNVFTPHGPDLYGTEPWYFYL-INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQ 341
Query: 292 ---KLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTL--------- 339
L+ + + H+E RFL P+ PL+ LS+
Sbjct: 342 NLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL-CGAVALSALQHSFLYFQKC 400
Query: 340 ---------------VNKKIFKGTWLLFNII-----MAFIMGISHQAGIIQFLGDYFHFR 379
+ + GT LF ++ +A G G + +++
Sbjct: 401 YHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGY---HGPLDLYPEFYRIA 457
Query: 380 TEQMGVH 386
T+ +H
Sbjct: 458 TD-PTIH 463
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
Length = 618
Score = 312 bits (792), Expect = 1e-83
Identities = 77/427 (18%), Positives = 132/427 (30%), Gaps = 73/427 (17%)
Query: 8 LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLV 67
+ + L L + DE F E + +G WE+ +A RSY LLL
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEP-THYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
P +Q N L+ Y +R + +C + + + V M + L
Sbjct: 121 AWPAAFHAR---ILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
+ S + + +S + M + S V G I +
Sbjct: 178 VLSTGMFCSSSAFLPSSFCMYTTLIA------MTGWYMDKTSIAVLGVAAGAILGWPFSA 231
Query: 188 RVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPL 247
+ P L + WK + F L++ V+ID+ Y VI PL
Sbjct: 232 ALGLPIAFDLLVMKHRWKSF------FHWSLMALILFLVPVVVIDSYYY---GKLVIAPL 282
Query: 248 NNLKYNLN-VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGY--------------- 291
N + YN+ ++G P Y +L +N LA+
Sbjct: 283 NIVLYNIFTPHGPDLYGTEPWYFYL-INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQ 341
Query: 292 ---KLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTL--------- 339
L+ + + H+E RFL P+ PL+ LS+
Sbjct: 342 NLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLICL-CGAVALSALQHSFLYFQKC 400
Query: 340 ---------------VNKKIFKGTWLLFNII-----MAFIMGISHQAGIIQFLGDYFHFR 379
+ + GT LF ++ +A G G + +++
Sbjct: 401 YHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGY---HGPLDLYPEFYRIA 457
Query: 380 TEQMGVH 386
T+ +H
Sbjct: 458 TD-PTIH 463
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
Length = 512
Score = 311 bits (789), Expect = 3e-83
Identities = 92/435 (21%), Positives = 160/435 (36%), Gaps = 77/435 (17%)
Query: 2 MRYQWWLYLVYAIGLMLCLGPS-YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
M+ + L+ A+ L Y PDE++Q +E+ A + G + WE+ RS
Sbjct: 1 MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEV-AHKLTFGYGYLTWEWVQG--IRS 57
Query: 61 YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120
Y LL+ G L+ IL D+ L++ R ++
Sbjct: 58 YVYPLLIAG-LYKILALLQL--DSAHLLVVLPR-------------------------IR 89
Query: 121 FMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLI 180
L+L + + + T +N++E L+ + +
Sbjct: 90 KWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWY-------GESTAYLWPAAIC 142
Query: 181 FSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFS----FSSCLFVLIDTNIY 236
F R T + + + R L+L F + L + IDT Y
Sbjct: 143 ----CFLRPTA---AVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDT--Y 193
Query: 237 NNGKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSG------ 290
+ ++TP LKYN+ +G HP + + V LP ++G L IF
Sbjct: 194 WH-GQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKK 252
Query: 291 ---YKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTP------LSSTLVN 341
Y + K I L+ LS +H+E RF+ PL+PL + + SST++
Sbjct: 253 SEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLW 312
Query: 342 KKIFKGTWLLFNIIMAFIMGISHQAGIIQFLG-------DYFHFRTEQMGVHIWWKTYSP 394
L+ N++ A+ + HQ G I+ + +Y R Q + +S
Sbjct: 313 TTAL--VILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHST 370
Query: 395 PTWMYMSNNLTVSSL 409
P + ++ N+T+ L
Sbjct: 371 PYYSHIHQNVTMRFL 385
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
Length = 533
Score = 299 bits (758), Expect = 1e-79
Identities = 118/416 (28%), Positives = 197/416 (46%), Gaps = 40/416 (9%)
Query: 9 YLVYAIGLMLCLG----PSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPL 64
++Y L+L SYIHPDEH Q +I A + K +PWEF +K RS PL
Sbjct: 8 AIIYTFLLILRFWFSQGSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSVVPL 67
Query: 65 LLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQK 124
++ P+F + + +P IL RL ++ LL + + + R +
Sbjct: 68 NVMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLIDLSIWNIVPLNARWS----AL 123
Query: 125 SLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFG 184
L +S++ T+QTHTF+NSIET+ T+ + + + ++ ++ + +L ++ G
Sbjct: 124 LLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIVSVLG 183
Query: 185 VFNRVTFPAFIFLPCLILFWKFYRVHWK------SFSLLLLSFSFSSCLFVLIDTNIYNN 238
F R+TF AF+ P + + ++ + + +S SF++ L +++ Y
Sbjct: 184 FFTRITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILED--YKF 241
Query: 239 GKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLST 298
FVIT NNLKYN ++NL HGLH R TH N+P + GP++ + + + K +T
Sbjct: 242 YGVFVITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGPLIFVPKL--WDVRKPAT 299
Query: 299 YAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAF 358
+ + + LS F HQE RFL+P + + N LV K ++++ +++A
Sbjct: 300 WLWLLPVFILSLFPHQEPRFLLPAASIFIVNSGC------LVRSYWIKFLFVMYAVVLAV 353
Query: 359 IMGISHQAGIIQFLGDY----------------FHFRTEQMGVHIWWKTYSPPTWM 398
GI HQ G+I + + +F E +WK YS PTWM
Sbjct: 354 FFGIMHQNGVIPAVLEVKNIIEQRNVTTMENCNLYFNPEMPTTIYFWKIYSAPTWM 409
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
(Schizosaccharomyces pombe)
emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
[Schizosaccharomyces pombe]
Length = 506
Score = 293 bits (745), Expect = 3e-78
Identities = 79/427 (18%), Positives = 152/427 (35%), Gaps = 43/427 (10%)
Query: 1 MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
++ ++WW L ++ PDE +Q +E+ A F+ G + WE+ S A RS
Sbjct: 9 ILVFRWWNAL---------WVKTFFQPDEFYQSLEV-AHHFIFRYGFLTWEWTS--AIRS 56
Query: 61 YGPLLLVYGPLFTILESFPEIQDNPALILY-SMRLQNYVMYLLCYHFLIPKLIRDERKAV 119
L++ L+ +L+ D+ + + +L + + +
Sbjct: 57 ALHP-LIFAALYRVLQVLKL--DSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKT 113
Query: 120 QFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDM--VNEKNIQRSNFKNSVIL 177
+ L S + TFSNS+ET + ++ S +L
Sbjct: 114 ANWTLACSLVSIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLL 173
Query: 178 GLIF--SFGVFNRVTFPAFIFLPC---------LILFWKFYRVHWKSFSLLLL------- 219
G I +F F R T P I + + F L
Sbjct: 174 GFISVAAFACFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLF 233
Query: 220 -SFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQI 278
F LF++ FV ++ ++N+ ++GL+ + +L LP I
Sbjct: 234 GIFVLCVSLFLVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLI 293
Query: 279 VGPVLLLAIFSGYKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSST 338
G L + + +D + I+ S H+ELRF+ P+ P+L+T SS
Sbjct: 294 CGGFLPFVLLT---MDLQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAG-KFFSSF 349
Query: 339 LVNKKIFKGTWL--LFNIIMAFIMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPT 396
K+ + +L L + ++ + HQ G+++ + + I ++ P
Sbjct: 350 SSWKRAARFFFLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKNQTGLILAPCHTTPW 409
Query: 397 WMYMSNN 403
++ +
Sbjct: 410 QSHIHSP 416
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
Length = 579
Score = 278 bits (705), Expect = 2e-73
Identities = 128/453 (28%), Positives = 182/453 (39%), Gaps = 73/453 (16%)
Query: 1 MMRYQWWLYLVYAIGLMLCLGPS--YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAA 58
M W L + ++ CL P Y+HPDE FQ E++A + V+ PWEF +
Sbjct: 32 MAVRVLWGGLSL-LRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSC 90
Query: 59 RSYGPLLLVYGPLFTILESFPEIQDNPALI-----LYSMRLQNYVMYLLCY---HFLIPK 110
RS LL+ G F +L + E+ P L+ L RL + + L P
Sbjct: 91 RSVLFPLLISGSTFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPP 150
Query: 111 LIRDERKAVQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSN 170
+ D +LL SYVT + T TFSN+IE L L ++ V ++
Sbjct: 151 MGADRWN-----ALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEP 205
Query: 171 FKN----SVILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVH---WKSFS----LLLL 219
S +LG I + G FNR TF AF +P W KS + +LL
Sbjct: 206 APGPRWRSWLLGGIVAAGFFNRPTFLAFAVVPL--YLWGTRGATNPGLKSLTREALVLLP 263
Query: 220 SFSFSSCLFVLIDTNIYNN---GKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLP 276
+ ++ +FV D+ +++ + V+TP+N L YNLN QNL HG H R THL VN
Sbjct: 264 GATLTAAVFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGF 323
Query: 277 QIVGPVLLLAIF--------------------------SGYKLDKLSTYAIISGLLFLSF 310
+ G + A+ L LS
Sbjct: 324 LLFGVLHAQALQAAWQQLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSA 383
Query: 311 FQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQAGIIQ 370
F HQE RFL+PL+ LV S +KGT +LFN + A + G HQ G++
Sbjct: 384 FSHQEARFLIPLLVPLVLLC------SPQTQPVPWKGTVVLFNALGALLFGCLHQGGLVP 437
Query: 371 FLGDYFHFRTEQMG--------VHIWWKTYSPP 395
L +Y ++ TY PP
Sbjct: 438 GL-EYLEQVVHAPVLPSTPTHYTLLFTHTYMPP 469
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
Length = 483
Score = 269 bits (683), Expect = 6e-71
Identities = 60/398 (15%), Positives = 114/398 (28%), Gaps = 41/398 (10%)
Query: 7 WLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVK----GTIPWEFKSKFAARSYG 62
L V I L++C Y +E F + + EF R++
Sbjct: 17 LLVTVATIHLVIC---PYTKVEESFNL--QATHDLLYHQLDIDKYDHHEF-PGVVPRTFL 70
Query: 63 PLLLVYG---PLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAV 119
L++ P+ +L + LI +R + + L ++ + V
Sbjct: 71 GPLVIAAFSSPVVYVLSLLEVSKFYSQLI---VRGVLGLGVISGLWTLQKEVRQQFGATV 127
Query: 120 QFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGL 179
M + T + Y T T N + ++ LT QR L
Sbjct: 128 AVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWL--------QRRWALFVW-LSA 178
Query: 180 IFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
G + I L + + + L V +D+ +
Sbjct: 179 FVIIGFRAELAMLLGIALLLTLYQRRLTVARV-LRHAIPAGL-LCLGLTVAVDSYFW--- 233
Query: 240 KGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLD-KLST 298
+ V L YN + G P + LP+ +G LL
Sbjct: 234 RYLVWPEGVVLGYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYALA 293
Query: 299 YAIISGLLFLSFFQHQELRFLVPLVPLLVTNL--NWTPLSSTLVNKKIFKGTWLLFNIIM 356
+ + S H+ELRF++ P+L T + + + + +I++
Sbjct: 294 LPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILNKKSWPYKVRAMLVTGHILV 353
Query: 357 -------AFIMGISHQAGIIQFLGDYFHFRTEQMGVHI 387
+ + + G + + Q V +
Sbjct: 354 NVAYTATSLYVSHFNYPGGV-AMQQLHELVPPQTDVLL 390
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
Length = 678
Score = 267 bits (677), Expect = 3e-70
Identities = 53/376 (14%), Positives = 106/376 (28%), Gaps = 47/376 (12%)
Query: 5 QWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMK----VKGTIPWEFKSKFAARS 60
A + +E F + ++ R+
Sbjct: 3 ILIFVTAAAHLVYTPFT----KVEESFNL--QAMHDILYLRNNFTQYDHHDY-PGVVPRT 55
Query: 61 YGPLLL---VYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERK 117
+ L+ + P + E+ + Y +RL + ++ L + +
Sbjct: 56 FIGPLVVSIISAPFVLLFETLSINKFWAQ---YVVRLVLAGAISVAWNSLRQAVTKIYGV 112
Query: 118 AVQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVIL 177
V+ ++ +T + Y T N ++ + Q F +I
Sbjct: 113 EVRLWFTAITITQFHFMFYMTRPLPNIFALPIVLFAIAYWLR------DQHKPF---IIC 163
Query: 178 GLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYN 237
I VF L + L + + L VL+D+ +
Sbjct: 164 SGISIL-VFRSELALFLGILLVVSLLRRKVSIDGLLKVALPAGVCI-LAATVLVDSFFW- 220
Query: 238 NGKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGY--KLDK 295
+ + L YN + G P + LP+ +G L+L +
Sbjct: 221 --RRLLWPEGEVLWYNTVLNKSSNWGTSPFLWYFYSALPRAMGASLVLVPIGVALEPRIR 278
Query: 296 LSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTW------ 349
+ + +L S H+ELRF++ + P+L + K TW
Sbjct: 279 PLVLSALLFVLLYSILPHKELRFIIYVFPVLNIAAACACQR---IWMNSAKSTWHSFLAL 335
Query: 350 -----LLFNIIMAFIM 360
LL N+ + +
Sbjct: 336 ACGAHLLLNVFITLFL 351
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
Length = 558
Score = 266 bits (674), Expect = 7e-70
Identities = 80/460 (17%), Positives = 159/460 (34%), Gaps = 89/460 (19%)
Query: 6 WWLYLVYAIGLMLCLGPSYIH-PDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPL 64
W + L + L LC + PDE +Q E+ A + KG +PWE+ ++ RS
Sbjct: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEV-AYNMVFGKGHLPWEW--RYGLRSVLFP 60
Query: 65 LLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIP--------------- 109
+V P + +L+ + ++ R+ ++ L +
Sbjct: 61 AVVALPFY-LLKLLGRDTTWA--VWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELE 117
Query: 110 -------------------KLIRDER---KAVQFMQKSLLLTSYVTWTYQTHTFSNSIET 147
+ R R ++ + L L+++ + N IE
Sbjct: 118 LAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEA 177
Query: 148 LALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFNRVTFPAFIFLPCLI------ 201
L ++ TL QR ++ GL + V + V +F
Sbjct: 178 LLVLLTL-----------QQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHG 226
Query: 202 LFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQNLQV 261
+R+ +L+ L Y +V+TPL ++N+ +
Sbjct: 227 FIRGLFRIVLTGLIVLVAVLGGVMVL-------DYCFYGRWVLTPLAFFRFNVLHNLSRF 279
Query: 262 HGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLD------------KLSTYAI---ISGLL 306
G HP Y ++ P +VG V +F+ + + L
Sbjct: 280 FGEHPWYFYV---GPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLG 336
Query: 307 FLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFK--GTWLLFNIIMAFIMGISH 364
F S H+E+RF+ ++PL + + + + + + K ++LFNI+M ++MG +
Sbjct: 337 FYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVY 396
Query: 365 QAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNL 404
+ G + + + + + Y+ P + YM +
Sbjct: 397 RRGPLDVMAEVRD-GPRINRLDVIATCYTVPGYSYMHKKV 435
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
Length = 623
Score = 265 bits (673), Expect = 1e-69
Identities = 71/413 (17%), Positives = 126/413 (30%), Gaps = 63/413 (15%)
Query: 8 LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLV 67
+ L + DE F E L + G WE+ +F RSY LLL
Sbjct: 77 FKTFVSARLCSAIWAYIADCDETFNYWEPL-HYIINGHGLQTWEYSPQFGLRSYTYLLLQ 135
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
P + + +P LI Y +R + ++ + ++ + +
Sbjct: 136 GVPGYFYQKL---FNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQ 192
Query: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
L S + T +S + L + +
Sbjct: 193 LFSVGMFVSSTALLPSSFSMYFGCAALAAWWQQNYC------------FAIFLTAISALL 240
Query: 188 RVTFPAFIFLPCLILFWKFYRVHWKSF-SLLLLSFSFSSCLFVLIDTNIYNNGKGFVITP 246
F A I +P ++ + WK+F L+S + + + IDT+ + P
Sbjct: 241 GWPFAALIGIPLVL-EMLLRQRDWKTFVQWTLISGATVAIPMIAIDTSYF---GKLTFAP 296
Query: 247 LNNLKYNLN-VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLD----------- 294
LN + YN+ + G P ++ +N + LLA+ L
Sbjct: 297 LNIVWYNVFTSHGPNIFGTEPLSYYI-INGFLNFNIIWLLALQLPIMLVIDYLIVPAKSK 355
Query: 295 -------KLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWT-------PLSSTLV 340
+S + LL H+E RFL P+ PL+ T V
Sbjct: 356 STLNFPHYISLAPLYLWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRMKSV 415
Query: 341 NKKIFKGTWLLFNIIMA--------FIMGIS-------HQAGIIQFLGDYFHF 378
KI G L + + ++G+S + + + + F
Sbjct: 416 VFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRVFALYRNYHAPMDLMLELNQF 468
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
- fission yeast (Schizosaccharomyces pombe)
emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
[Schizosaccharomyces pombe]
Length = 577
Score = 264 bits (669), Expect = 3e-69
Identities = 63/356 (17%), Positives = 123/356 (33%), Gaps = 32/356 (8%)
Query: 4 YQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
+ W ++ + L DE + E L + G WE+ ++A RS+
Sbjct: 14 FVWTFSILAVLRLTSASFRVIDDCDEVYNYWEPL-HYLLYGYGLQTWEYSPEYAIRSWFY 72
Query: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQ 123
+ L P F + + Y +R C LI + R+ +AV
Sbjct: 73 IALHAVPGFLARGL----GLSRLHVFYFIRGVLACFSAFCETNLILAVARNFNRAVALHL 128
Query: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSF 183
S+L + W+ T +S + L+ ++ + +R+ S I
Sbjct: 129 TSVLFVNSGMWSASTSFLPSSFAMNMVTLALSA---QLSPPSTKRTVKVVSFITIGAVIG 185
Query: 184 GVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFV 243
F+ FI L + L +F + + F + ++ + + +++ + FV
Sbjct: 186 WPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLIT--GICITVDSLFYHRIQFV 243
Query: 244 ITPLNNLKYNLNVQ---NLQVHGLHPRYTHLLVN---------LPQIVGPVLLLAIFSGY 291
N +KYN+ + ++G P + + GP++LLA F+ +
Sbjct: 244 --AWNIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLVLLAAFTNW 301
Query: 292 -------KLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLV 340
L + + L H+E RF+ P+ P+L S +
Sbjct: 302 INLDSFLDLSSVIS-PFYIWLFIFIIQPHKEERFMYPIYPVLCLAAAIGLDMSLKL 356
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
Length = 488
Score = 253 bits (640), Expect = 7e-66
Identities = 58/400 (14%), Positives = 111/400 (27%), Gaps = 43/400 (10%)
Query: 7 WLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKV----KGTIPWEFKSKFAARSYG 62
L V + L++C Y +E F + + EF R++
Sbjct: 16 LLVAVATVHLVIC---PYTKVEESFNL--QATHDLLYHWQDLEQYDHLEF-PGVVPRTFL 69
Query: 63 PLLLVYG---PLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAV 119
+++ P +L + LI +R + + L ++ R V
Sbjct: 70 GPVVIAVFSSPAVYVLSLLEMSKFYSQLI---VRGVLGLGVIFGLWTLQKEVRRHFGAMV 126
Query: 120 QFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGL 179
M + + Y T T N + ++ L I
Sbjct: 127 ATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWA----------RFIWLS 176
Query: 180 IFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
F+ VF L L L + V + L V +D+ +
Sbjct: 177 AFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGI-LCLGLTVAVDSYFW--- 232
Query: 240 KGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLD-KLST 298
+ L YN + G P + LP+ +G LL T
Sbjct: 233 RQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPT 292
Query: 299 YAIISGLLFLSFFQHQELRFLVPLVPLLVTNLN----WTPLSSTLVNKKIFKGTWLLFNI 354
+ + S H+ELRF++ P+L + + ++ ++
Sbjct: 293 VLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHL 352
Query: 355 IM-------AFIMGISHQAGIIQFLGDYFHFRTEQMGVHI 387
++ A + + G + + Q V +
Sbjct: 353 VVNAAYSATALYVSHFNYPGGV-AMQRLHQLVPPQTDVLL 391
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
mannosyltransferase [Homo sapiens]
Length = 488
Score = 252 bits (638), Expect = 1e-65
Identities = 58/400 (14%), Positives = 111/400 (27%), Gaps = 43/400 (10%)
Query: 7 WLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKV----KGTIPWEFKSKFAARSYG 62
L V + L++C Y +E F + + EF R++
Sbjct: 16 LLVAVATVHLVIC---PYTKVEESFNL--QATHDLLYHWQDLEQYDHLEF-PGVVPRTFL 69
Query: 63 PLLLVYG---PLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAV 119
+++ P +L + LI +R + + L ++ R V
Sbjct: 70 GPVVIAVFSSPAVYVLSLLEMSKFYSQLI---VRGVLGLGVIFGLWTLQKEVRRHFGAMV 126
Query: 120 QFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGL 179
M + + Y T T N + ++ L I
Sbjct: 127 ATMFCWVTAMQFHLMVYCTRTLPNVLALPVVLLALAAWLRHEWA----------RFIWLS 176
Query: 180 IFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
F+ VF L L L + V + L V +D+ +
Sbjct: 177 AFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGI-LCLGLTVAVDSYFW--- 232
Query: 240 KGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLD-KLST 298
+ L YN + G P + LP+ +G LL T
Sbjct: 233 RQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPT 292
Query: 299 YAIISGLLFLSFFQHQELRFLVPLVPLLVTNLN----WTPLSSTLVNKKIFKGTWLLFNI 354
+ + S H+ELRF++ P+L + + ++ ++
Sbjct: 293 VLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHL 352
Query: 355 IM-------AFIMGISHQAGIIQFLGDYFHFRTEQMGVHI 387
++ A + + G + + Q V +
Sbjct: 353 VVNAAYSATALYVSHFNYPGGV-AMQRLHQLVPPQTDVLL 391
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
could be the target of the GPI synthesis inhibitor,
YW3548; Most likely an alpha 1,2 mannosyltransferase
utilized for the addition of the third mannose onto the
GPI core structure.; Gpi1>
sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
cerevisiae)
emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
Length = 616
Score = 244 bits (618), Expect = 3e-63
Identities = 77/429 (17%), Positives = 143/429 (32%), Gaps = 58/429 (13%)
Query: 1 MMRYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
++ Y L L++ L P Y + +Q E + +P++ RS
Sbjct: 88 LLHYALLLLSTIGSDLLILLLPKY---ELSWQVAE----DLKR----LPFDVT-----RS 131
Query: 61 YGPLLLVYGP--LFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERK- 117
+ ++Y P + +L S E Y +R + L +
Sbjct: 132 FEYYGVIYAPKIVMAVLASIGE--------YYIVRFVQKLYLLTLDKRNEKEEEERRSGL 183
Query: 118 -AVQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVI 176
+ L LT++ + T TF NS E + L D + I+ S+F S+I
Sbjct: 184 SEITKFALLLSLTNFFNCFFITRTFINSFEMILTSIALYYW-DWTGGQMIKESSFTKSLI 242
Query: 177 LGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSS----CLFVLID 232
R + +P + L K + LL ++FS +F
Sbjct: 243 FAF---LACLQRPSSGLIWVIPSISLILNLVGK--KQYHLLFITFSKVLRSFFLVFTANA 297
Query: 233 TNIYNNGKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYK 292
+ LK+N + +G+ P + H +LP ++G + F +
Sbjct: 298 IIDMYFYEKVTFPFFRFLKFNFTTPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFF 357
Query: 293 LDK-------------LSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLS--- 336
I+ LL S H+E RF+ PL PL + ++ L
Sbjct: 358 PLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLDR 417
Query: 337 --STLVNK-KIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYS 393
++ K ++ +A ++ H++G I+ + + H E + +S
Sbjct: 418 DYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVM-KFLHEEPEIDSLGFIMPCHS 476
Query: 394 PPTWMYMSN 402
P Y+
Sbjct: 477 TPGQSYLHR 485
Score = 41.5 bits (97), Expect = 0.031
Identities = 16/61 (26%), Positives = 24/61 (39%), Gaps = 5/61 (8%)
Query: 6 WWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLL 65
W L L ++ DE +Q +E A G + WE+ KF RSY +
Sbjct: 19 WVFL--AFRVLNAVLTRTFFQADEFWQALEP-AHWKAFKYGELTWEW--KFGVRSYLFPM 73
Query: 66 L 66
+
Sbjct: 74 I 74
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
Length = 919
Score = 244 bits (617), Expect = 3e-63
Identities = 67/344 (19%), Positives = 119/344 (34%), Gaps = 37/344 (10%)
Query: 4 YQWWL-YLVYAIGLMLCLGPSYIH-PDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSY 61
+W+L ++ + + IH DE F E L + G WE+ S FA RSY
Sbjct: 393 LRWFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPL-HYILYKSGFQTWEYSSNFALRSY 451
Query: 62 GPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQF 121
+++ L S+ D+ + Y++RL ++ + L+ L R K +
Sbjct: 452 LY--ILFHELAGRPASWW-FGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIAT 508
Query: 122 MQKSLLLTSYVTWTYQTHTFSNSIETLA--LISTLTVMEDMVNEKNIQRSNFKNSVILGL 179
++L + + T +S A L S L + E +
Sbjct: 509 YAVAMLCLTSGCFFASTSFLPSSFSMYAISLSSGLLLFEKYA--------------MAVA 554
Query: 180 IFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNG 239
+ GV F FLP +I +K + + L+ Y
Sbjct: 555 VSVVGVILGWPFSILAFLPVVIYSLVKR---FKQAFIAGAVTTIFLLGVSLLVDYYY--Y 609
Query: 240 KGFVITPLNNLKYNLNVQN-LQVHGLHPRYTHL--------LVNLPQIVGPVLLLAIFSG 290
K + + LN L YN+ ++G ++ + ++ + I
Sbjct: 610 KRWTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIRRK 669
Query: 291 YKLDKLSTY-AIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWT 333
Y L + L F+S H+E RFL P+ PL+ + +
Sbjct: 670 YDRALLVVISPMYIWLAFMSLQPHKEERFLYPIYPLICVSASAV 713
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
Length = 492
Score = 241 bits (610), Expect = 2e-62
Identities = 44/363 (12%), Positives = 115/363 (31%), Gaps = 29/363 (7%)
Query: 7 WLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKV-----KGTIPWEFKSKFAARSY 61
W+ ++ I ++ + +E F M +F R++
Sbjct: 6 WIVIIVTIIHIILAPGT--KVEESFNV--QATHDLMFHLPTNLSNYDHSQF-PGVVPRTF 60
Query: 62 GPLL---LVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKA 118
+ ++ P+ I + + L++ R +M + + + + R +
Sbjct: 61 IGPISLAILSSPMSFIFRFWAIPKMWQLLLI---RATLGLMNAMAFLYFARSVNRKFGRE 117
Query: 119 VQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILG 178
+ ++ T + Y + N+ + ++ + + E + SVIL
Sbjct: 118 TAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYESAV--RYATASVIL- 174
Query: 179 LIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNN 238
F + + + K + ++ + + + + ID+ +
Sbjct: 175 ----FRCELVLLYGPIFLGYMISGRLKVFGFDGAI-AIGVRIAAMCLAVSIPIDSYFW-- 227
Query: 239 GKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQI--VGPVLLLAIFSGYKLDKL 296
+ + +N+ +G P + LP+ +L+ +
Sbjct: 228 -GRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQ 286
Query: 297 STYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIM 356
+ + SF H+ELRF++ ++P+ + + K F L F +I+
Sbjct: 287 IVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFFRMILFFGVIL 346
Query: 357 AFI 359
+
Sbjct: 347 HLL 349
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
lipid-linked oligosaccharides; Alg9p [Saccharomyces
cerevisiae]
sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
cerevisiae)
emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
Length = 555
Score = 233 bits (590), Expect = 5e-60
Identities = 60/342 (17%), Positives = 116/342 (33%), Gaps = 29/342 (8%)
Query: 9 YLVYAIGLMLCLGPSYI--------HPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
+ ++ L+L L YI DE F E L ++ G WE+ +++ RS
Sbjct: 5 AVTISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPL-NLLVRGFGKQTWEYSPEYSIRS 63
Query: 61 YGPLLLVYGPLFTILESFPEIQD-NPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAV 119
+ LL P + IL + D + R + L ++ +
Sbjct: 64 WAFLL----PFYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQI 119
Query: 120 QFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGL 179
+ L + + +++ L + ++ + SNF S+
Sbjct: 120 ANIWIIFQLFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGST--SNFTKSLAYNF 177
Query: 180 IFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLL--LLSFSFSSCLFVLIDTNIYN 237
F + LP + + +R+ + L FS ++ ++ D+ Y
Sbjct: 178 ---LASILGWPFVLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFY- 233
Query: 238 NGKGFVITPLNNLKYNLN----VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYK- 292
N L YN+ + G+ P Y + L L PVL+LAI +
Sbjct: 234 --GKLAPVSWNILFYNVINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHL 291
Query: 293 LDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTP 334
++ + + + H+E RFL P+ L+ + +
Sbjct: 292 RLWPLWASLFTWIAVFTQQPHKEERFLYPIYGLITLSASIAF 333
Score = 233 bits (590), Expect = 5e-60
Identities = 60/342 (17%), Positives = 116/342 (33%), Gaps = 29/342 (8%)
Query: 9 YLVYAIGLMLCLGPSYI--------HPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60
+ ++ L+L L YI DE F E L ++ G WE+ +++ RS
Sbjct: 5 AVTISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPL-NLLVRGFGKQTWEYSPEYSIRS 63
Query: 61 YGPLLLVYGPLFTILESFPEIQD-NPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAV 119
+ LL P + IL + D + R + L ++ +
Sbjct: 64 WAFLL----PFYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQI 119
Query: 120 QFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGL 179
+ L + + +++ L + ++ + SNF S+
Sbjct: 120 ANIWIIFQLFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGST--SNFTKSLAYNF 177
Query: 180 IFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLL--LLSFSFSSCLFVLIDTNIYN 237
F + LP + + +R+ + L FS ++ ++ D+ Y
Sbjct: 178 ---LASILGWPFVLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFY- 233
Query: 238 NGKGFVITPLNNLKYNLN----VQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYK- 292
N L YN+ + G+ P Y + L L PVL+LAI +
Sbjct: 234 --GKLAPVSWNILFYNVINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHL 291
Query: 293 LDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTP 334
++ + + + H+E RFL P+ L+ + +
Sbjct: 292 RLWPLWASLFTWIAVFTQQPHKEERFLYPIYGLITLSASIAF 333
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
Length = 570
Score = 230 bits (582), Expect = 5e-59
Identities = 63/342 (18%), Positives = 118/342 (34%), Gaps = 33/342 (9%)
Query: 4 YQWWL-YLVYAIGLMLCLGPSYIH-PDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSY 61
+W+L ++ + + IH DE F E L + G WE+ S FA RSY
Sbjct: 44 LRWFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPL-HYILYKSGFQTWEYSSNFALRSY 102
Query: 62 GPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQF 121
+++ L S+ D+ + Y++RL ++ + L+ L R K +
Sbjct: 103 LY--ILFHELAGRPASWW-FGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIAT 159
Query: 122 MQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIF 181
++L + + T +S A+ + ++ + +
Sbjct: 160 YAVAMLCLTSGCFFASTSFLPSSFSMYAISLSSGLLLFEKYA------------MAVAVS 207
Query: 182 SFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKG 241
GV F FLP +I +K + + L+ Y K
Sbjct: 208 VVGVILGWPFSILAFLPVVIYSLVKR---FKQAFIAGAVTTIFLLGVSLLVDYYY--YKR 262
Query: 242 FVITPLNNLKYNLNVQN-LQVHGLHPRYTHL--------LVNLPQIVGPVLLLAIFSGYK 292
+ + LN L YN+ ++G ++ + ++ + I Y
Sbjct: 263 WTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIRRKYD 322
Query: 293 LDKLSTY-AIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWT 333
L + L F+S H+E RFL P+ PL+ + +
Sbjct: 323 RALLVVISPMYIWLAFMSLQPHKEERFLYPIYPLICVSASAV 364
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
Length = 369
Score = 229 bits (580), Expect = 7e-59
Identities = 38/311 (12%), Positives = 101/311 (32%), Gaps = 19/311 (6%)
Query: 54 SKFAARSYGPLL---LVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPK 110
R++ + ++ P+ I + + L++ R +M + + +
Sbjct: 11 PGVVPRTFIGPISLAILSSPMSFIFRFWAIPKMWQLLLI---RATLGLMNAMAFLYFARS 67
Query: 111 LIRDERKAVQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSN 170
+ R + + ++ T + Y + N+ + ++ + + E +
Sbjct: 68 VNRKFGRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYESAV--RY 125
Query: 171 FKNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVL 230
SVIL F + + + K + ++ + + + +
Sbjct: 126 ATASVIL-----FRCELVLLYGPIFLGYMISGRLKVFGFDGAI-AIGVRIAAMCLAVSIP 179
Query: 231 IDTNIYNNGKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQI--VGPVLLLAIF 288
ID+ + + + +N+ +G P + LP+ +L+
Sbjct: 180 IDSYFW---GRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGL 236
Query: 289 SGYKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGT 348
+ + + SF H+ELRF++ ++P+ + + K F
Sbjct: 237 LVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFFRM 296
Query: 349 WLLFNIIMAFI 359
L F +I+ +
Sbjct: 297 ILFFGVILHLL 307
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
Length = 830
Score = 229 bits (580), Expect = 8e-59
Identities = 112/497 (22%), Positives = 181/497 (35%), Gaps = 123/497 (24%)
Query: 12 YAIGLMLCLGPS--YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLVYG 69
A+ L+L P Y+HPDE FQ +E++ +++ T WEF + RS +++
Sbjct: 24 AAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRS----IVLPF 79
Query: 70 PLFTILESFPEIQDNPALILY------------SMRLQNYVMYLLCYHFLIPKLIRDERK 117
L I SF E + RL ++ + L + R
Sbjct: 80 ALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGL 138
Query: 118 AVQFMQKSLLL-TSYVTWTYQTHTFSNSIETLALIS-------------TLTVMEDMVNE 163
+F + L + +S++ + T TFSNS+E T+ ++ + E
Sbjct: 139 --RFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEE 196
Query: 164 K------------------NIQRSNFKNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWK 205
K ++ N ++ + + I GVFNR TF F ++ FW
Sbjct: 197 KYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFG--APMVFFWL 254
Query: 206 FYR-----VHWKSFSLLLLSFSFS----SCLFVLIDTNIYNNGK------------GFVI 244
+ ++ F+L + F LF+ D+ Y + FV
Sbjct: 255 LRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVF 314
Query: 245 TPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYK------------ 292
TP N +K NL+ HG+HP Y HL+VN+P + L LA +
Sbjct: 315 TPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNV-LALASLGAFAQLLLRFFRAEYQ 373
Query: 293 -------LDKLSTYAIISGLLFLSFFQHQELRFLVPL-VPLLVTNLN------------- 331
+ L + AI L FLS HQE RFL+P+ PL++ +
Sbjct: 374 VLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQ 433
Query: 332 ---------WTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYFHF---R 379
+ L S+ + W + N+ + G HQAG+ D H +
Sbjct: 434 KDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATK 493
Query: 380 TEQMGVHIWW-KTYSPP 395
VH+ YS P
Sbjct: 494 PAATHVHLITSHIYSLP 510
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
(Swiss Prot accession number P38376)~cDNA EST yk549e12.3
comes from this gene~cDNA EST yk618d6.3 comes from this
gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
yk618d6.5 comes from>
Length = 653
Score = 229 bits (579), Expect = 1e-58
Identities = 57/344 (16%), Positives = 107/344 (30%), Gaps = 44/344 (12%)
Query: 7 WLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLL 66
++ +I + + DE + E L F+ +G WE+ +A RSY + L
Sbjct: 56 VFKMLLSIRISGAIWGIINDCDEVYNYWEPL-HLFLYGEGFQTWEYSPVYAIRSYFYIYL 114
Query: 67 VYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSL 126
Y P D ++ +RL + LL ++ + + A
Sbjct: 115 HYIPASL---FANLFGDTKIVVFTLIRLTIGLFCLLGEYYAFDAICKKINIATGRFFILF 171
Query: 127 LLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVF 186
+ S + T +S T ++ +NE V + +
Sbjct: 172 SIFSSGMFLASTAFVPSSFCMA---ITFYILGAYLNENWTAG---IFCVAFSTMVGWPFS 225
Query: 187 NRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITP 246
+ P + L + + L++ + V+ D++ + V+ P
Sbjct: 226 AVLGLPIVADMLLLKGLRIRF-----ILTSLVIGLCIG-GVQVITDSHYF---GKTVLAP 276
Query: 247 LNNLKYNLNVQ-NLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFS---------------- 289
LN YN+ ++G P ++ NL V+ A F
Sbjct: 277 LNIFLYNVVSGPGPSLYGEEPLSFYI-KNLFNNWNIVIFAAPFGFPLSLAYFTKVWMSQD 335
Query: 290 -------GYKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLL 326
+ L + LL H+E RFL P+ P +
Sbjct: 336 RNVALYQRFAPIILLAVTTAAWLLIFGSQAHKEERFLFPIYPFI 379
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
(Schizosaccharomyces pombe)
emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
architecture [Schizosaccharomyces pombe]
Length = 547
Score = 214 bits (542), Expect = 3e-54
Identities = 57/382 (14%), Positives = 115/382 (29%), Gaps = 46/382 (12%)
Query: 20 LGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLVYGPLFTILESFP 79
IH + ++ KV + + RS+ P L + +L P
Sbjct: 36 FAMQAIHDIQTYRW------DLSKVYDHLEF---PGAVKRSFIPSLFIA-----VLSYIP 81
Query: 80 EIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLLLTSYVTWTYQTH 139
NP L + R + + + + + + + Y +
Sbjct: 82 SWFVNPLL---AARWTIGYLSWESMNSVSCSISKRFGTLSGALFILFSCAQFHLVYYMSR 138
Query: 140 TFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFNRVTFPAFIFLPC 199
SN +A +L+++ +I I F + A + +
Sbjct: 139 PLSNIFGLIATNHSLSLLLKNNYYGSIS------------ILVFAAAIVRSEIALLLMCL 186
Query: 200 LILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQNL 259
++ R+ L+ +S S ++ + + + + L +N+
Sbjct: 187 ILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFW--GAWCWPELEAFLFNVVEGKS 244
Query: 260 QVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYAIISGLLF---LSFFQHQEL 316
G P Y + + + P LL + + K + I L F SF H+E
Sbjct: 245 SDWGTSPFYYYFVRLPWLFLNPTTLLFLLISFVYIKPARLLIYVPLFFIFVYSFLGHKEW 304
Query: 317 RFLVPLVPLLVTNLNWT---PLSSTLVNKKIFKGTWLLFNIIMA---------FIMGISH 364
RF++ +P +++ KKIF+ L+F + +
Sbjct: 305 RFIIYSIPWFNAASAIGASLCFNASKFGKKIFEILRLMFFSGIIFGFIGSSFLLYVFQYA 364
Query: 365 QAGIIQFLGDYFHFRTEQMGVH 386
G + Y Q+ VH
Sbjct: 365 YPGGLALTRLYEIENHPQVSVH 386
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
cerevisiae)
emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
Length = 551
Score = 202 bits (510), Expect = 1e-50
Identities = 61/419 (14%), Positives = 124/419 (29%), Gaps = 77/419 (18%)
Query: 4 YQW-----WLYLVYAIGLMLC--------LGPSYIHPDEHFQCIEILAMQFMKVKGTIPW 50
+W L V + L+ IH + +I +K
Sbjct: 1 MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKF------ 54
Query: 51 EFKSKFAARSYGPLLLVYG---PLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFL 107
R++ +++ P + + + +R + L + +L
Sbjct: 55 ---PGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYL 111
Query: 108 IPKLIRDE------------------RKAVQFMQKSLLLTSYVTWTYQTHTFSNSIETLA 149
L + L+ S+ Y T T N
Sbjct: 112 KNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPN------ 165
Query: 150 LISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRV 209
+ TL + + + R N + L + + V+ + + F ++
Sbjct: 166 FVMTLPLTNVALGWVLLGRYNAA--IFLSALVAIVFRLEVSALSAGI---ALFSVIFKKI 220
Query: 210 HWKS-FSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQNLQVHGLHPRY 268
+ S + + +D+ + + + ++ +N+ G+ P
Sbjct: 221 SLFDAIKFGIFGLGLGSAISITVDSYFWQE---WCLPEVDGFLFNVVAGYASKWGVEPVT 277
Query: 269 THLLVNLPQIVGP--VLLLAIFS---GYKLDKLSTYAIISGLLFLSFFQHQELRFLVPLV 323
+ L + P VLLL F K+ + A + ++ LSF H+E RF++ V
Sbjct: 278 AYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAV 337
Query: 324 PLLVTNLNWTPLSSTLVNKKIFKGTWLL------------FNIIMA-FIMGISHQAGII 369
P ++ T + N K+ K T +L F I MA + + G
Sbjct: 338 PSIMLL-GATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGE 395
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
Length = 457
Score = 201 bits (507), Expect = 3e-50
Identities = 94/335 (28%), Positives = 134/335 (39%), Gaps = 62/335 (18%)
Query: 109 PKLIRDERKAVQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQR 168
P + D +LL SYVT + T TFSN+IE L L ++ V ++
Sbjct: 27 PAMGADRWN-----ALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRK 81
Query: 169 SNFKN----SVILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVH---WKSFS----LL 217
S +LG I + G FNR TF AF +P W KS + +L
Sbjct: 82 EPAPGPRWRSWLLGGIVAAGFFNRPTFLAFAVVPL--YLWGTRGATNPGLKSLTREALVL 139
Query: 218 LLSFSFSSCLFVLIDTNIYNN---GKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVN 274
L + ++ +FV D+ +++ + V+TP+N L YNLN QNL HG H R THL VN
Sbjct: 140 LPGATLTAAVFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVN 199
Query: 275 LPQIVGPVLLLAIFSGYKL--------------------------DKLSTYAIISGLLFL 308
+ G + A+ + ++ L L
Sbjct: 200 GFLLFGVLHAQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALL 259
Query: 309 SFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQAGI 368
S F HQE RFL+PL+ LV S +KGT LFN + A + G HQ G+
Sbjct: 260 SAFSHQEARFLIPLLVPLVLLC------SPQTQPVPWKGTVALFNALGALLFGCLHQGGL 313
Query: 369 IQFLGDYFHFRTEQMG--------VHIWWKTYSPP 395
+ L +Y ++ TY PP
Sbjct: 314 VPGL-EYLEQVVHAPVLPSTPTHYTLLFTHTYMPP 347
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
Length = 509
Score = 201 bits (507), Expect = 3e-50
Identities = 47/328 (14%), Positives = 103/328 (31%), Gaps = 26/328 (7%)
Query: 9 YLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLVY 68
L + + Y HPDE FQ +E A + IPWE++ ++
Sbjct: 28 LLALCLRMTAIFPIGYYHPDEIFQYLEQ-AHRLAFGYSVIPWEYRYGMRGGLVP---VLL 83
Query: 69 GPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLLL 128
+ +I + + + + + + L + KL R + +
Sbjct: 84 AAAMKM----GDIMNTQSFLYWVLPHAITALLSLGVIWSAYKLGRLHSFFTGCLAMFVAA 139
Query: 129 TSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFNR 188
T Y + H S S+ A + + + ++S+ S L + +
Sbjct: 140 TWYEIVLFAAHPLSESLSFAAFMPAAYYL----IAEEKKKSSLILSGFLMGLSAL----- 190
Query: 189 VTFPAFIFLPCLILFWKFY-RVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPL 247
F ++P ++ F R++ + + +L + + +
Sbjct: 191 ---LRFQYIPSILFITLFTLRINVRQWGYFILG-GLGAVFISSLSDIFIGEYPLLWL--F 244
Query: 248 NNLKYNLNVQNLQVHGLHPRYTHLLVNL--PQIVGPVLLLAIFSGYKLDKLSTYAIISGL 305
N++ NL + +G P Y++ + +L + I + L
Sbjct: 245 KNIQQNLIFHRAEDYGTAPIYSYFFDIWTNWKWFSLILPIPILVAAYRYPALFGTALVNL 304
Query: 306 LFLSFFQHQELRFLVPLVPLLVTNLNWT 333
+F H+E RF+ + +
Sbjct: 305 IFHMLVSHKEYRFIFLSSGIFIILAAIG 332
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
chromosome I precursor [Leishmania major]
Length = 822
Score = 173 bits (437), Expect = 4e-42
Identities = 48/354 (13%), Positives = 92/354 (25%), Gaps = 67/354 (18%)
Query: 7 WLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLL 66
+L L P DE F IE + + G WE S+FA RS+ L +
Sbjct: 15 FLLLSLTHYFASSFLP-ISDCDETFNFIEPI-HYLLYGSGKQTWEVCSRFALRSWLFLWI 72
Query: 67 VYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSL 126
P+ I + + + + +R+ N L F + + + L
Sbjct: 73 HAWPVVLIRGAASL---SSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVALLL 129
Query: 127 LLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKN-------IQRSNFKNSVILGL 179
LL +Y S + L + + + +N++
Sbjct: 130 LLANYPIQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLSRVGDRPTQNTMPAAA 189
Query: 180 I--------------------------------------------FSFGVFNRVTFPAFI 195
V F A +
Sbjct: 190 AGTAQLSMMVPPSPSSAPTLHSSSASPPSAPPRHLCWFIGAALCFSVLAVVTGWPF-AAL 248
Query: 196 FLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLN 255
+ L ++ + L +C V + Y + ++ N + YN
Sbjct: 249 ISALVGLDLLLR-FPVRTLACTL-GSLLVACAAVFVADVRY--YCRWTLSSWNVVMYNGF 304
Query: 256 VQ---NLQVHGLHPRYTH---LLVNLPQIVGPVLLLAIFSGYKLDKLSTYAIIS 303
++ G+ P + L++N + VLL + +
Sbjct: 305 GGSGRGPELFGVEPIFFFWKNLMLNFHLMFVVVLLAPVVLLCAPRRELAATSAL 358
Score = 41.9 bits (98), Expect = 0.025
Identities = 9/35 (25%), Positives = 13/35 (36%)
Query: 300 AIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTP 334
LF H+E RF+ P P ++ T
Sbjct: 441 PFFVWFLFWMSIAHKEERFMSPAYPFMLLAATRTL 475
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
Length = 198
Score = 148 bits (371), Expect = 3e-34
Identities = 27/131 (20%), Positives = 46/131 (34%), Gaps = 4/131 (3%)
Query: 8 LYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLV 67
+ + L L + DE F E + +G WE+ +A RSY LLL
Sbjct: 62 FKCLLSARLCAALLSNISDCDETFNYWEP-THYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
P +Q N L+ Y +R + +C + + + V M + L
Sbjct: 121 AWPAAFHAR---ILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 128 LTSYVTWTYQT 138
+ S + +
Sbjct: 178 VLSTGMFCSSS 188
>gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protein MGC3136 [Mus musculus]
Length = 385
Score = 134 bits (336), Expect = 3e-30
Identities = 33/227 (14%), Positives = 60/227 (25%), Gaps = 27/227 (11%)
Query: 7 WLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVK----GTIPWEFKSKFAARSYG 62
L V I L++C Y +E F + + EF R++
Sbjct: 17 LLVTVATIHLVIC---PYTKVEESFNL--QATHDLLYHQLDIDKYDHHEF-PGVVPRTFL 70
Query: 63 PLLLVYG---PLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAV 119
L++ P+ +L + LI +R + + L ++ + V
Sbjct: 71 GPLVIAAFSSPVVYVLSLLEVSKFYSQLI---VRGVLGLGVISGLWTLQKEVRQQFGATV 127
Query: 120 QFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGL 179
M + T + Y T T N + ++ LT QR L
Sbjct: 128 AVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWL--------QRRWALFVW-LSA 178
Query: 180 IFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSC 226
G + I L + + +
Sbjct: 179 FVIIGFRAELAMLLGIALLLTLYQRRLTVARV-LRHAIPAGL-LCLG 223
Score = 44.3 bits (104), Expect = 0.006
Identities = 15/151 (9%), Positives = 40/151 (25%), Gaps = 36/151 (23%)
Query: 269 THLLVNLPQIVGPVLLLAIFSGYKLDKLSTYAIISGLLFLSFFQHQEL------------ 316
+ LP ++ ++L + + + +A+ L +
Sbjct: 143 FYCTRTLPNVLALAVVLPALTAWLQRR---WALFVWLSAFVIIGFRAELAMLLGIALLLT 199
Query: 317 ---------RFLVPLVP--LLVT--NLNWTPLSSTLVNKKIFKGTWLLFNIIM------- 356
R L +P LL + L + + + +I++
Sbjct: 200 LYQRRLTVARVLRHAIPAGLLCLGKLASLVCLLNKKSWPYKVRAMLVTGHILVNVAYTAT 259
Query: 357 AFIMGISHQAGIIQFLGDYFHFRTEQMGVHI 387
+ + + G + + Q V +
Sbjct: 260 SLYVSHFNYPGGV-AMQQLHELVPPQTDVLL 289
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
Length = 197
Score = 130 bits (326), Expect = 5e-29
Identities = 31/211 (14%), Positives = 66/211 (30%), Gaps = 17/211 (8%)
Query: 116 RKAVQFMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSV 175
+ + Y + SN +A +L+++ +I
Sbjct: 1 GTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKNNYYGSIS-------- 52
Query: 176 ILGLIFSFGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNI 235
I F + A + + ++ R+ L+ +S S ++ + +
Sbjct: 53 ----ILVFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSY 108
Query: 236 YNNGKGFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDK 295
+ + L +N+ G P Y + + + P LL + + K
Sbjct: 109 FW--GAWCWPELEAFLFNVVEGKSSDWGTSPFYYYFVRLPWLFLNPTTLLFLLISFVYIK 166
Query: 296 LSTYAIISGLLF---LSFFQHQELRFLVPLV 323
+ I L F SF H+E RF++ +
Sbjct: 167 PARLLIYVPLFFIFVYSFLGHKEWRFIIYSI 197
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
Length = 283
Score = 128 bits (319), Expect = 3e-28
Identities = 27/133 (20%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 252 YNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAI--FSGYKLDKLSTYAIISG---LL 306
+N+ + G+HP Y +++ +P ++ ++ I G + + S + ++
Sbjct: 131 FNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYII 190
Query: 307 FLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQ- 365
S H+E RFL+P++PLL + + + NI +A HQ
Sbjct: 191 VHSLLPHKEQRFLLPIIPLLCIYAG-GAFQNLKKWRGSAMAVMIAINIGIALFTSRYHQK 249
Query: 366 ---AGIIQFLGDY 375
G I +Y
Sbjct: 250 HSCNGTIVEHPEY 262
Score = 68.4 bits (166), Expect = 3e-10
Identities = 18/73 (24%), Positives = 33/73 (44%), Gaps = 7/73 (9%)
Query: 1 MMRYQWWLYLVYAIGLMLC----LGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKF 56
++R + L L+ + + C L S+ PDE +Q E+ A + G + WE++
Sbjct: 62 VLRMRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEV-AHHLVYGTGHLSWEWRHSL 120
Query: 57 AARSYGPLLLVYG 69
RS+ L+
Sbjct: 121 --RSFFHPALIAF 131
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
Length = 278
Score = 123 bits (308), Expect = 7e-27
Identities = 27/134 (20%), Positives = 49/134 (36%), Gaps = 11/134 (8%)
Query: 279 VGPVLLLAIFSGYKLDK----LSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNWTP 334
G L+ S K I+ LL S H+E RF+ PL PL + ++
Sbjct: 15 FGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGL 74
Query: 335 LS-----STLVNK-KIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYFHFRTEQMGVHIW 388
L ++ K ++ +A ++ H++G I+ + + H E +
Sbjct: 75 LRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVM-KFLHEEPEIDSLGFI 133
Query: 389 WKTYSPPTWMYMSN 402
+S P Y+
Sbjct: 134 MPCHSTPGQSYLHR 147
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
[Caenorhabditis elegans]
Length = 232
Score = 121 bits (303), Expect = 2e-26
Identities = 27/133 (20%), Positives = 53/133 (39%), Gaps = 10/133 (7%)
Query: 252 YNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAI--FSGYKLDKLSTYAIISG---LL 306
+N+ + G+HP Y +++ +P ++ ++ I G + + S + ++
Sbjct: 67 FNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYII 126
Query: 307 FLSFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQ- 365
S H+E RFL+P++PLL + + + NI +A HQ
Sbjct: 127 VHSLLPHKEQRFLLPIIPLLCIYAG-GAFQNLKKWRGSAMAVMIAINIGIALFTSRYHQK 185
Query: 366 ---AGIIQFLGDY 375
G I +Y
Sbjct: 186 HSCNGTIVEHPEY 198
Score = 61.4 bits (148), Expect = 3e-08
Identities = 17/70 (24%), Positives = 30/70 (42%), Gaps = 7/70 (10%)
Query: 4 YQWWLYLVYAIGLMLC----LGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAAR 59
+ L L+ + + C L S+ PDE +Q E+ A + G + WE++ R
Sbjct: 1 MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEV-AHHLVYGTGHLSWEWRHSL--R 57
Query: 60 SYGPLLLVYG 69
S+ L+
Sbjct: 58 SFFHPALIAF 67
>ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
pir||S75173 hypothetical protein sll1946 - Synechocystis sp. (strain PCC 6803)
dbj|BAA17087.1| (D90903) ORF_ID:sll1946~unknown protein [Synechocystis sp. PCC
6803]
Length = 825
Score = 44.6 bits (105), Expect = 0.004
Identities = 40/392 (10%), Positives = 104/392 (26%), Gaps = 66/392 (16%)
Query: 10 LVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPLLLVYG 69
L Y + + L E ++ W K+ +Y +V
Sbjct: 46 LSYGLEYLQALRSPEFLSGEWWRSF---------------WMLSPKYPPLTY----IVNA 86
Query: 70 PLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLLLT 129
P + ++ + + + + + + ++++
Sbjct: 87 PFQGLGGPGSDLALLSNWLW----------SGILILSVYGLGKKLFSREIGLWAVAIMVL 136
Query: 130 SYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFNRV 189
+ +++ L TL + K + + + G+
Sbjct: 137 IPRLIHSRLIVL---LDSPLLAFTLLSFTCLTYWKEAEGRRSQWLWAIAAGVGLGLGLLS 193
Query: 190 TFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNN 249
+L ++ + + K + L + + ++
Sbjct: 194 KQSIIFYLFFPLVGLGLWSIWTKQWQ-RLAQLLVGLLASIPL--WYPWYRTNWIYLFSTA 250
Query: 250 LKYNLNVQNLQVHGLHPR-----YTHLLVNLPQIV-GPVLLLAIFSGYK----------- 292
N N + G P +T+ +LP + L+ +
Sbjct: 251 --QNSNAIPATLEGDPPVNTLAAWTYYWQDLPNALSWVWLIPPLVGVILSLLNRFPASLQ 308
Query: 293 -LDKLSTYAIISGLLFL--------SFFQHQELRFLVPLVPLLVTNLNWTPLSSTLVNKK 343
+ L + S Q+++ R+++P +P++ L +
Sbjct: 309 IPSWREAKPGLLWLGYYYGGTYLICSAIQNKDDRYILPYLPIVAIFLAFGLTRWCGRWLW 368
Query: 344 IFKGTWLLFNIIMAF--IMGISHQAGIIQFLG 373
+ GT + I++ + I GI+Q L
Sbjct: 369 VRWGTLAIT-ILITLGNLFPIPGSNGIVQALN 399
>ref|NP_488731.1| (NC_003272) unknown protein [Nostoc sp. PCC 7120]
dbj|BAB76390.1| (AP003597) ORF_ID:alr4691~unknown protein [Nostoc sp. PCC 7120]
Length = 541
Score = 36.5 bits (84), Expect = 1.1
Identities = 43/276 (15%), Positives = 83/276 (29%), Gaps = 20/276 (7%)
Query: 68 YGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQKSLL 127
GP + I + N +S+RL + + +LC FL+ ++ + + +
Sbjct: 76 PGPYWLIASFYQLFGVNE----FSVRLPSMIFGVLC-LFLVYEIGKIMLGKTLAWLSAAI 130
Query: 128 LTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFN 187
L+ W + + + + L+ + R F S I+GL G
Sbjct: 131 LSVEFLWLQYSRLGNPDLPMIFLVLLAIYLLIQAELHPQYRDYF--SFIVGLSLGLGFLM 188
Query: 188 RVTFPAFI--FLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVIT 245
R +F F+ L + R + L L ++ + T
Sbjct: 189 R-SFVIFLPTVALLPYLITEHRRHRHLTNPWLYLGVVIGFIPILIWSWFNWQRDGNNTFT 247
Query: 246 PLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIV------GPVLLLAIFSGYKLDKLSTY 299
L N + + + + + L + LLL I + L
Sbjct: 248 HLVNF---VFLLGSEERDGNGILFYFWNTLLKAFPWPCFSLLGLLLIIRRPWHRYNLILI 304
Query: 300 AIISGLLF-LSFFQHQELRFLVPLVPLLVTNLNWTP 334
LL L+ F + + + L P +
Sbjct: 305 GFPIVLLAELTIFSTRLSHYALSLYPFIALLAAVGL 340
>ref|NP_069450.1| (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
pir||H69326 conserved hypothetical protein AF0616 - Archaeoglobus fulgidus
gb|AAB90624.1| (AE001062) conserved hypothetical protein [Archaeoglobus fulgidus]
Length = 533
Score = 34.5 bits (79), Expect = 4.3
Identities = 50/395 (12%), Positives = 118/395 (29%), Gaps = 63/395 (15%)
Query: 6 WWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQ---FMKVKGTIPWEFKSKFAARSYG 62
L L+ ++ +I D+ Q + F+ +F +Y
Sbjct: 12 LVLLLITTFVVIT--NVYFIAWDDSPQSWDPALHLTYSFVYFNLIKSLQFSEIVKVSNYY 69
Query: 63 PLLLVYG--PLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120
P PL+ + +I LI Y + + ++ + +
Sbjct: 70 PPFFYLSSTPLYFLFGFSEDIAILTNLIYYF-----------ILIYSVFQIAKIMKDRNA 118
Query: 121 FMQKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLI 180
+ +++++++ + L +LT ++ ++ N K SV+ G++
Sbjct: 119 GVISAVIISAFPALIKFQRVYMIDFALL----SLTAFAILLYLRSEDFRNLKYSVLFGIV 174
Query: 181 FSFGVFNRVTF-----PAFIFLPCLILFWK---FYRVHWKSFSLLLLSFS---------- 222
F + P+ L + F + +++ + + F
Sbjct: 175 FGIAELTKWNAFVYIIPSIFALFLVNYFMRCPYCHQIVKNGWKVGYRRFCSKKHLKLYEK 234
Query: 223 ----------FSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQN---LQVHGLHPRYT 269
F+ LFV + + + +
Sbjct: 235 SAKTNNTMLNFAISLFVAFLFAAWWYLPNLSTVIMRLTYFANIGGKEGDPAFLTIQGWIY 294
Query: 270 HLLVNLPQIVGPVLLLAIFSGYKLDKL-------STYAIISGLLFLSFFQHQELRFLVPL 322
+ L + L+L S Y L K I + L+ +++ R+++P+
Sbjct: 295 YANSILDAVGAVFLILFAVSIYYLYKNNRYLFLGLLTPIALIYIILTLLSNKDPRYIMPV 354
Query: 323 VPLLVTNLNWTPLSSTLVNKKI--FKGTWLLFNII 355
+P + ++ +SS K LLF ++
Sbjct: 355 LPFVAISIG-VFVSSLANRKYSTILTFIILLFGLL 388
CPU time: 154.34 user secs. 3.99 sys. secs 158.33 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.317 0.178 0.501
Gapped
Lambda K H
0.270 0.0623 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 370388278
Number of Sequences: 887402
Number of extensions: 20624271
Number of successful extensions: 93214
Number of sequences better than 10.0: 935
Number of HSP's better than 10.0 without gapping: 62
Number of HSP's successfully gapped in prelim test: 895
Number of HSP's that attempted gapping in prelim test: 91872
Number of HSP's gapped (non-prelim): 1705
length of query: 516
length of database: 277,845,442
effective HSP length: 52
effective length of query: 464
effective length of database: 231,700,538
effective search space: 107509049632
effective search space used: 107509049632
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 76 (33.6 bits)