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GPI Anchor Biosynthesis Report: AAF47201.1 (SMP3 family, Drosophila melanogaster)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (830 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 6

Distribution of 109 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 893 0.0
ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 409 e-113
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 368 e-100
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 366 e-100
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 336 1e-90
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 329 7e-89
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 328 2e-88
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 312 2e-83
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 312 2e-83
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 308 2e-82
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 304 3e-81
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 303 5e-81
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 302 1e-80
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 295 2e-78
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 293 1e-77
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 272 1e-71
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 269 2e-70
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 260 6e-68
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 245 3e-63
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 234 4e-60
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 233 7e-60
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 233 7e-60
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 232 1e-59
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 232 2e-59
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 225 2e-57
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 195 2e-48
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 186 1e-45
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 174 4e-42
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 145 3e-33
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 137 5e-31
gb|AAF55584.1| (AE003723) CG7709 gene product [Drosophila melano... 118 5e-25
gb|AAF48706.1| (AE003504) CG5095 gene product [Drosophila melano... 114 8e-24
gb|AAF48345.1| (AE003495) CG11584 gene product [Drosophila melan... 113 2e-23
gb|AAF49498.1| (AE003527) CG13043 gene product [Drosophila melan... 103 1e-20
ref|XP_082817.1| (XM_082817) CG5095 [Drosophila melanogaster] 103 1e-20
gb|AAL49309.1| (AY071687) RH10371p [Drosophila melanogaster] 102 3e-20
ref|XP_082690.1| (XM_082690) CG1368 [Drosophila melanogaster] >g... 97 1e-18
gb|AAF46806.1| (AE003456) CG13504 gene product [Drosophila melan... 94 7e-18
gb|AAF49497.1| (AE003527) CG13063 gene product [Drosophila melan... 85 4e-15
gb|AAF50552.1| (AE003559) CG8541 gene product [Drosophila melano... 81 7e-14
gb|AAF46963.1| (AE003459) CG13545 gene product [Drosophila melan... 74 9e-12
gb|AAF48347.1| (AE003495) CG11585 gene product [Drosophila melan... 69 2e-10
Alignments
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
          Length = 830

 Score =  893 bits (2284), Expect = 0.0
 Identities = 830/830 (100%), Positives = 830/830 (100%)

Query: 1   MRLTTLWQNRSPGDRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEH 60
           MRLTTLWQNRSPGDRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEH
Sbjct: 1   MRLTTLWQNRSPGDRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEH 60

Query: 61  TRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTL 120
           TRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTL
Sbjct: 61  TRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTL 120

Query: 121 ISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSEC 180
           ISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSEC
Sbjct: 121 ISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSEC 180

Query: 181 MLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRP 240
           MLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRP
Sbjct: 181 MLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRP 240

Query: 241 TFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLG 300
           TFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLG
Sbjct: 241 TFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLG 300

Query: 301 ELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAF 360
           ELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAF
Sbjct: 301 ELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAF 360

Query: 361 AQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAP 420
           AQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAP
Sbjct: 361 AQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAP 420

Query: 421 KLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVY 480
           KLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVY
Sbjct: 421 KLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVY 480

Query: 481 PLAADISHVIATKPAATHVHLITSHIYSLPLHLINIPSSRVLHFNRLTHQRYRRPRDFYM 540
           PLAADISHVIATKPAATHVHLITSHIYSLPLHLINIPSSRVLHFNRLTHQRYRRPRDFYM
Sbjct: 481 PLAADISHVIATKPAATHVHLITSHIYSLPLHLINIPSSRVLHFNRLTHQRYRRPRDFYM 540

Query: 541 YEYGGLPLDSLLQKVKLISGSCEVKKSGPSRRRYKLYLAIPASLSADLHEALVHSNASSY 600
           YEYGGLPLDSLLQKVKLISGSCEVKKSGPSRRRYKLYLAIPASLSADLHEALVHSNASSY
Sbjct: 541 YEYGGLPLDSLLQKVKLISGSCEVKKSGPSRRRYKLYLAIPASLSADLHEALVHSNASSY 600

Query: 601 LNFELLKVFYPHLSTEAFPHLQGRHPCDVDAPHWAHDDLRGTCSAEQLPAFSFAYLNKQF 660
           LNFELLKVFYPHLSTEAFPHLQGRHPCDVDAPHWAHDDLRGTCSAEQLPAFSFAYLNKQF
Sbjct: 601 LNFELLKVFYPHLSTEAFPHLQGRHPCDVDAPHWAHDDLRGTCSAEQLPAFSFAYLNKQF 660

Query: 661 SSFVHQLGLALYEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFI 720
           SSFVHQLGLALYEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFI
Sbjct: 661 SSFVHQLGLALYEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFI 720

Query: 721 ASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTY 780
           ASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTY
Sbjct: 721 ASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTY 780

Query: 781 AAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPILKKK 830
           AAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPILKKK
Sbjct: 781 AAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPILKKK 830
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase -like protein [Arabidopsis
           thaliana]
 gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
          Length = 548

 Score =  409 bits (1041), Expect = e-113
 Identities = 95/516 (18%), Positives = 152/516 (29%), Gaps = 108/516 (20%)

Query: 20  YFCF-AAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLP 78
            F F  A R++   + Q  Y +PDE +QS+EV     F      TWE+     +RS + P
Sbjct: 41  IFLFCLAFRVVNALLIQT-YFNPDEHWQSLEVAHRTIFGY-GYMTWEW--KRGIRSYLHP 96

Query: 79  FALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYG- 137
                         A   K      L   Y  +  PRL+ ++ S   D  L+++      
Sbjct: 97  M-----------LFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYG 145

Query: 138 --LRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLE 195
             +        M  +W +     RTFSN LE  +                       +  
Sbjct: 146 GNVATWSLFCQMA-NWFIFFCLNRTFSNCLETVLTI------------------MGLYYW 186

Query: 196 EKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLL 255
                +       R W L                 I       RPT  +         L 
Sbjct: 187 PCIRDSSIDYPVNRKWGLV----------------IAALACAIRPTSAVIW-------LY 223

Query: 256 RGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFT 315
            GM    +T       I          L      D L Y                  V  
Sbjct: 224 VGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSW---------------VIV 268

Query: 316 PWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVL 375
           P NF+K N  S+    +G HP + +      ++                  F  A   + 
Sbjct: 269 PLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVML------------FTFTPFSIAGI-IK 315

Query: 376 PRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKL----ITGFSAKYP 431
            + Q +    S  I   L   S++ H+E RF+LPV    ++          ++G S+   
Sbjct: 316 SKNQKL----SALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSS 371

Query: 432 FQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIA 491
             K   + R  + K         Y       +N+ + L+    HQ G       +S    
Sbjct: 372 VTKKKQVPRQNHTKWSPKLRLSVYF---LLATNIPMALYMSLFHQRGTEDAMNYLSDEAY 428

Query: 492 TKP-------AATHVHLITSHIY-SLPLHLINIPSS 519
                        H     S ++ ++P+  ++   S
Sbjct: 429 KGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPS 464
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
          Length = 558

 Score =  368 bits (936), Expect = e-100
 Identities = 77/500 (15%), Positives = 157/500 (31%), Gaps = 69/500 (13%)

Query: 18  STYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVL 77
                    RL L    +     PDE++QS EV     F  +    WE+     +RS++ 
Sbjct: 4   WLISLTFIYRLFLCATIRTVEA-PDEWWQSTEVAYNMVFG-KGHLPWEW--RYGLRSVL- 58

Query: 78  PFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYG 137
                     F   VA        L    T+A    PR++  L+    D  +F  C    
Sbjct: 59  ----------FPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVF--CMGAT 106

Query: 138 LRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEK 197
           L   +    +  +       T+ FS   E+++      + +        +     ++   
Sbjct: 107 LDELLAKRELELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYM--A 164

Query: 198 YDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRG 257
           Y         +    +  +L        + ++ +       R T  +  +          
Sbjct: 165 YCGVRLYGNVIEALLVLLTLQQRRYVPFLLLTGLAS---AIRVTSAVVLS-------PLV 214

Query: 258 MGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPW 317
               +   R+            +  L   +    +    +  G + + +     +V TP 
Sbjct: 215 FRHLANATREH---------GFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPL 265

Query: 318 NFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPR 377
            F + N+    +   G HP Y ++    P+L  ++    L   A  L   +R        
Sbjct: 266 AFFRFNVLHNLSRFFGEHPWYFYV---GPVLVGIVGPHVLFTIAAPL-VLWRDTASRAVS 321

Query: 378 FQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHP 437
              +  L  GA  +   F SLI+H+E RF+  V           LIT       + +   
Sbjct: 322 RPVLGMLGIGAWTLG--FYSLIDHKEMRFVFVVIPL-------SLITAAFVLVRWSRTSA 372

Query: 438 LLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATKP--- 494
           ++                + +++ + N+ +    G++++ G   + A++           
Sbjct: 373 VVVK--------------MNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDV 418

Query: 495 -AATHVHLITSHIYSLPLHL 513
            A  +     S+++    HL
Sbjct: 419 IATCYTVPGYSYMHKKVNHL 438
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
           GPI-anchor biosynthesis [Mus musculus]
 dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
          Length = 542

 Score =  366 bits (932), Expect = e-100
 Identities = 95/540 (17%), Positives = 162/540 (29%), Gaps = 139/540 (25%)

Query: 2   RLTTLW----QNRSP-----GDRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMT 52
           R +  +    + RSP     G+      F   A+R+L  F+ Q  +V PDE++QS+EV  
Sbjct: 27  RKSRQYVSAQEKRSPRRGLLGENTYLVLFTI-ALRILNCFLVQTSFV-PDEYWQSLEVAH 84

Query: 53  GDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVV 112
              F      TWE+     +R             ++    A   K    L        + 
Sbjct: 85  RMVFSY-GYLTWEWTER--LRGY-----------TYPLIFASIYKVLHLLGKDSVQFLIW 130

Query: 113 FPRL---IYTLISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAM 169
            PRL   + + ++    Y L +      +   + L  +  SW      TRT +N++E ++
Sbjct: 131 IPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQL-CSWFTWYCCTRTLTNTMETSL 189

Query: 170 CSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMS 229
            +  L                                          L      + +  S
Sbjct: 190 TALALF--------------------------------------YYPLEGSRSVNSIKYS 211

Query: 230 TICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFC 289
            +       RPT        +  W+           R  +L +  F         L +  
Sbjct: 212 LLVALACVVRPTA-------LIPWVPLLFRHFYQEQRKLHLTLHHFLPVGFITFSLSLII 264

Query: 290 DSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLF 349
           D +++   TL +                NF+K N+       +G HP + +L    P++ 
Sbjct: 265 DRIFFGQWTLVQ---------------LNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVL 309

Query: 350 NVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLP 409
                          L FF     + PR   I+ L        L   S++ H+E RF+ P
Sbjct: 310 G------------THLPFFIHGCFLAPRRLHILLLTVLWT---LLVYSMLGHKEFRFIYP 354

Query: 410 VTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTL 469
           V    ++     L    + +                           L    +SNV L  
Sbjct: 355 VLPFCMVFCGYSLAHLKTWRK------------------------AALSFLLLSNVPLAF 390

Query: 470 FFGFIHQAGVYPLAADISHVIATKP----------AATHVHLITSHIYSL-PLHLINIPS 518
           + G +HQ G   +   I  V    P             H     SH++    +  +  P 
Sbjct: 391 YTGLVHQRGTLDVMNHIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPP 450
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
           could be the target of the GPI synthesis inhibitor,
           YW3548; Most likely an alpha 1,2 mannosyltransferase
           utilized for the addition of the third mannose onto the
           GPI core structure.; Gpi1>
 sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
 pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
 emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
          Length = 616

 Score =  336 bits (853), Expect = 1e-90
 Identities = 89/570 (15%), Positives = 169/570 (29%), Gaps = 147/570 (25%)

Query: 19  TYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLP 78
            ++ F A R+L   + +  +   DEF+Q++E      F+     TWE+     VRS + P
Sbjct: 17  IFWVFLAFRVLNAVLTRT-FFQADEFWQALEPAHWKAFKY-GELTWEW--KFGVRSYLFP 72

Query: 79  F----------------------------ALLRIPWSFYEFVAECLKAWWQLELLG---- 106
                                         LL +    YE   +  +   +L        
Sbjct: 73  MIFELTYRLVSLSSILLHYALLLLSTIGSDLLILLLPKYELSWQVAEDLKRLPFDVTRSF 132

Query: 107 -TYAYVVFPRLIYTLISFSNDYCLFRICRLYGLRFEI--------------------RLL 145
             Y  +  P+++  +++   +Y + R  +   L                         LL
Sbjct: 133 EYYGVIYAPKIVMAVLASIGEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFALL 192

Query: 146 AMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESIS 205
              +++    F TRTF NS EM + S  L                               
Sbjct: 193 LSLTNFFNCFFITRTFINSFEMILTSIALY------------------------------ 222

Query: 206 ERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITF 265
                W     +   +    +  +         RP+  L         +L  +G     +
Sbjct: 223 --YWDWTGGQMIKESSFTKSLIFAF---LACLQRPSSGLIWVIPSISLILNLVGK--KQY 275

Query: 266 RDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLD 325
               +  +                D  +Y+ +T               F  + F+K N  
Sbjct: 276 HLLFITFSKVLRSFFLVFTANAIIDMYFYEKVT---------------FPFFRFLKFNFT 320

Query: 326 SAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLM 385
           +  +  +GV P + H   ++P++      A        L +    +  + P FQ  +   
Sbjct: 321 TPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKL--- 377

Query: 386 SGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDK 445
              I + L   S + H+E RF+ P+    IL+ +  L+              L R ++ +
Sbjct: 378 --TILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLR-------------LDRDYWKR 422

Query: 446 LLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATKP----AATHVHL 501
           L   K+    +       +V + L     H++G   +   +               H   
Sbjct: 423 LSGLKSLLWLVPF----VSVFIALLLDTFHESGSIEVMKFLHEEPEIDSLGFIMPCHSTP 478

Query: 502 ------------ITSHIYSLPLHLINIPSS 519
                       + S   + PLHL+  P +
Sbjct: 479 GQSYLHRSDIQDLWSITCNPPLHLLGDPEA 508
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
 dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
          Length = 579

 Score =  329 bits (837), Expect = 7e-89
 Identities = 152/508 (29%), Positives = 214/508 (41%), Gaps = 89/508 (17%)

Query: 25  AVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRI 84
            +R+L   +PQ GYVHPDEFFQS EVM  D   ++  R WEF  S   RS++ P  LL  
Sbjct: 43  LLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFP--LLIS 100

Query: 85  PWSFYEFVAECLKAWWQL----ELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGLRF 140
             +F+       + W +L     L+  YA +V PRL+ T +SF+ D  ++ +    G   
Sbjct: 101 GSTFWLL-----RLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADR 155

Query: 141 EIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDK 200
              L  +  S++ LVF TRTFSN++E  + +WLL LVS  +    T             K
Sbjct: 156 WNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPT------------RK 203

Query: 201 AESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGT 260
             +   R R W                +  I  AG FNRPTFL F    ++ W  RG   
Sbjct: 204 EPAPGPRWRSWL---------------LGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATN 248

Query: 261 RSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFI 320
             +          +    A     +F+  DS Y+                N V TP NF+
Sbjct: 249 PGLKS--LTREALVLLPGATLTAAVFVATDSWYFSSPATSR---------NLVLTPVNFL 297

Query: 321 KANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQV-LPRFQ 379
             NL+    A HG H    HL VN  +LF VL   +L A  Q L    +A  Q+ L R  
Sbjct: 298 HYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQQLQVGLQASAQMGLLRAL 357

Query: 380 SIVSLMSGA-------IFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPF 432
              SL+S          F+PL  LS  +HQE RFL+P+  PL+LL +P+     +   P+
Sbjct: 358 GARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSPQ-----TQPVPW 412

Query: 433 QKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGV---YPLAADISHV 489
           +                            + N    L FG +HQ G+         + H 
Sbjct: 413 KGTV------------------------VLFNALGALLFGCLHQGGLVPGLEYLEQVVHA 448

Query: 490 IATKPAATHVHLITSHIYSLPLHLINIP 517
                  TH  L+ +H Y  P HL+++P
Sbjct: 449 PVLPSTPTHYTLLFTHTYMPPRHLLHLP 476
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
           [Schizosaccharomyces pombe]
          Length = 506

 Score =  328 bits (833), Expect = 2e-88
 Identities = 99/517 (19%), Positives = 167/517 (32%), Gaps = 108/517 (20%)

Query: 19  TYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLP 78
            ++    V      +    +  PDEF+QS+EV     FR     TWE+ +   +RS +  
Sbjct: 4   WFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRY-GFLTWEWTS--AIRSALH- 59

Query: 79  FALLRIPWSFYEFVAECLKAWWQLELLGTYAYVV-FPRLIYTLISFSNDYCLFRICRL-Y 136
                         A   +    L+L  +Y      P+L+    +   DY  ++   + Y
Sbjct: 60  ----------PLIFAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRY 109

Query: 137 GLRFEIRLLAMGSSWILLVF-GTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLE 195
           G +     LA     I+  + G RTFSNSLE  + S                     +  
Sbjct: 110 GSKTANWTLACSLVSIMNAYVGVRTFSNSLETTLTSI------------------GFYYF 151

Query: 196 EKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTI--CVAGVFNRPTFLLFGAPMVFFW 253
             Y K E+ S   R              +   +  I       F RPT +L     + FW
Sbjct: 152 SYYLKYENSSPEQRKK-----------AYSSLLGFISVAAFACFIRPTNILVWIFPLLFW 200

Query: 254 LLRGMG--TRSITFRDFNLRI-ALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSID 310
                      ++F +   R   L+ L       +F+ C SL+  ++         +   
Sbjct: 201 NKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVSLFLVNIIADR-----ILYG 255

Query: 311 NFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRA 370
            FVF   +F + N+ S  ++ +G++  + +L   +P++        L             
Sbjct: 256 RFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPFVLLT----------- 304

Query: 371 EYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKY 430
                     +    +G I    F  SLI H+E RF+ P++  L+ L             
Sbjct: 305 ----------MDLQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAG----------- 343

Query: 431 PFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVI 490
                      F+    S K +  +   I     + +T      HQ GV  +   I  + 
Sbjct: 344 ----------KFFSSFSSWKRAARFFFLIGLGHALVITFLCR-FHQFGVMEVMPLIHSLA 392

Query: 491 ATKP-----AATHVHLITSHIYSLPL----HLINIPS 518
                    A  H     SHI+S         +    
Sbjct: 393 EKNQTGLILAPCHTTPWQSHIHSPFAENGWKFLTCEP 429
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
 gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
 gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
          Length = 623

 Score =  312 bits (792), Expect = 2e-83
 Identities = 56/466 (12%), Positives = 119/466 (25%), Gaps = 88/466 (18%)

Query: 30  LVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFY 89
           L           DE F   E +          +TWE++    +RS            ++ 
Sbjct: 85  LCSAIWAYIADCDETFNYWEPLHYIINGH-GLQTWEYSPQFGLRSY-----------TYL 132

Query: 90  EFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMG 148
                    + +L            R +        +  +++ IC+ +G+        +G
Sbjct: 133 LLQGVPGYFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIH-------IG 185

Query: 149 SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESISERV 208
             W++                 S    L S   +          +               
Sbjct: 186 RLWLIFQL-------FSVGMFVSSTALLPSSFSMYFGCAALAAWW--------------- 223

Query: 209 RIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDF 268
                       N    + ++ I            L         +        +  RD 
Sbjct: 224 ----------QQNYCFAIFLTAISAL---------LGWPFAALIGIPLV-LEMLLRQRD- 262

Query: 269 NLRIALFCLCALPALVL-FIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSA 327
                 + L +   + +  I  D+ Y+  LT               F P N +  N+ ++
Sbjct: 263 WKTFVQWTLISGATVAIPMIAIDTSYFGKLT---------------FAPLNIVWYNVFTS 307

Query: 328 -QTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMS 386
                 G  P   +++    + FN++ L +L     L++ +     +          +  
Sbjct: 308 HGPNIFGTEPLSYYIINGF-LNFNIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISL 366

Query: 387 GAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAP---KLITGFSAKYPFQKDHPLLRLFY 443
             +++ L       H+E RFL P+   + L  A         F              + Y
Sbjct: 367 APLYLWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRMKSVVFKIK-AGVHY 425

Query: 444 DKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHV 489
                  A    +       +    L+  +        L  +++  
Sbjct: 426 LDHSMFIAILVMVTSTLLGLSRVFALYRNY---HAPMDLMLELNQF 468
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
 pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
          Length = 533

 Score =  312 bits (792), Expect = 2e-83
 Identities = 109/516 (21%), Positives = 178/516 (34%), Gaps = 118/516 (22%)

Query: 14  DRHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVR 73
           +R  +  + F  +     F     Y+HPDE  QS ++     F  +    WEF    P+R
Sbjct: 4   NRKYAIIYTFLLILRFW-FSQGSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIR 62

Query: 74  SIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRIC 133
           S+ +P  ++ +P         C            Y  ++F RL   LIS   D  ++ I 
Sbjct: 63  SV-VPLNVMLLP-----IFLLCRCICKSN--CSPYPILLFTRLYMCLISLLIDLSIWNIV 114

Query: 134 RLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEF 193
            L        LL   SS++   F T TF+NS+E       +  +S+              
Sbjct: 115 PLN--ARWSALLLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKL------------- 159

Query: 194 LEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFW 253
                    +     +           +  +   ++ + V G F R TFL F      ++
Sbjct: 160 ---------NSVPLNKKI---------SYLYTFLLAIVSVLGFFTRITFLAFVIAPYIYF 201

Query: 254 LLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFV 313
            +R         +D  L + +F   +   ++  I  D  +Y                 FV
Sbjct: 202 SVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDYKFYG---------------VFV 246

Query: 314 FTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQ 373
            T WN +K N      + HG+H    H   NMP+L   L                     
Sbjct: 247 ITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGPLIF------------------- 287

Query: 374 VLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQ 433
            +P+   +    +    +P+F LSL  HQEPRFLLP     I+                 
Sbjct: 288 -VPKLWDVRKPATWLWLLPVFILSLFPHQEPRFLLPAASIFIVNSG-------------- 332

Query: 434 KDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATK 493
               L+R ++ K             ++ +  V L +FFG +HQ GV P   ++ ++I  +
Sbjct: 333 ---CLVRSYWIK------------FLFVMYAVVLAVFFGIMHQNGVIPAVLEVKNIIEQR 377

Query: 494 PAATH------------VHLITSHIYSLPLHLINIP 517
              T               +    IYS P  ++  P
Sbjct: 378 NVTTMENCNLYFNPEMPTTIYFWKIYSAPTWMLARP 413
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
 dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
          Length = 506

 Score =  308 bits (783), Expect = 2e-82
 Identities = 84/527 (15%), Positives = 148/527 (27%), Gaps = 129/527 (24%)

Query: 12  PGDRHLSTYF--------CFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRT 63
             D   +              A R     + +  Y +PDE +Q +EV     F      T
Sbjct: 33  RPDLPWAWALGSERRVLALALAFRAANALLVRT-YFNPDEHWQCLEVAHRIVFGY-GHLT 90

Query: 64  WEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISF 123
           WE+     +RS + PF             A   K    L L   +   + PRL+ ++ + 
Sbjct: 91  WEW--KRGLRSYLHPF-----------IFAALYKILSLLHLDSPWFMAMAPRLLQSVFAS 137

Query: 124 SNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSN---SLEMAMCSWLLCLVSEC 180
             D  L+++ +L                         F+N    +E  +    L      
Sbjct: 138 FGDLYLYKLSKLI------------------------FNNHVAHMETVLTVTGLY----- 168

Query: 181 MLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRP 240
                    K   +  K   A   S   R                     I       RP
Sbjct: 169 YWFVAIESVKGNSVVSKQQAASKQSPPSRK----------------MALLIAALACAIRP 212

Query: 241 TFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLG 300
           T  +       +  L          R   L +          L +F+   + +       
Sbjct: 213 TSAITW----LYVGLLDFIQMKSKSRFIFLEV--------VPLGVFVLAVTTFLDCW--- 257

Query: 301 ELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAF 360
                     + +  P NF+K NL S+    +G H  + +     P +            
Sbjct: 258 -------MYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLP------ 304

Query: 361 AQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAP 420
                  F     +  R   +  L+       L   S++ H+E RF+LPV   + +    
Sbjct: 305 -------FSISGILKSREWRLAGLIVW----VLVVYSILGHKEFRFVLPVLPFMFMFSG- 352

Query: 421 KLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVY 480
                 +A    +      +    +L          + +  ++NV + L+    HQ G  
Sbjct: 353 ---HNLAAMAQLKGKGHNEKGRLSRL-------KLSVILLILTNVPMALYMSLYHQRGTE 402

Query: 481 PLAADIS---HVIATKP----AATHVHLITSHIY-SLPLHLINIPSS 519
                +S   H    K        H     S ++ +LP+  ++   S
Sbjct: 403 DAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLPMRFLDCTPS 449
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
           - fission yeast (Schizosaccharomyces pombe)
 emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
           [Schizosaccharomyces pombe]
          Length = 577

 Score =  304 bits (772), Expect = 3e-81
 Identities = 60/456 (13%), Positives = 111/456 (24%), Gaps = 82/456 (17%)

Query: 19  TYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLP 78
             F   AV  L     +      DE +   E +    +     +TWE++    +RS    
Sbjct: 16  WTFSILAVLRLTSASFR-VIDDCDEVYNYWEPLHYLLYGY-GLQTWEYSPEYAIRSWF-- 71

Query: 79  FALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGL 138
                   +         +      L   Y      R +    S   +  L  +      
Sbjct: 72  ---YIALHAVP---GFLARGLGLSRLHVFYFI----RGVLACFSAFCETNLI-LAVARNF 120

Query: 139 RFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKY 198
              + L      ++                  +    L S   +   T+           
Sbjct: 121 NRAVALHLTSVLFVN------------SGMWSASTSFLPSSFAMNMVTLALS-------- 160

Query: 199 DKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGM 258
                +S       +K                      F     ++         +   +
Sbjct: 161 ---AQLSPPSTKRTVKVVS-------------------FITIGAVIGWPFSAALSIPFIL 198

Query: 259 GTRSI---TFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFT 315
                    FR    R       AL    + I  DSL+Y                   F 
Sbjct: 199 LELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFY---------------HRIQFV 243

Query: 316 PWNFIKANLDSA---QTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEY 372
            WN +K N+ +        +G  P   +   N+ +  N++   ++     +LL  F    
Sbjct: 244 AWNIVKYNVLAKDGRGPDIYGTEPW-WYYFANLSLQHNIVLWFAMACGPLVLLAAFTNWI 302

Query: 373 QVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPF 432
            +       +S +    ++ LF   +  H+E RF+ P+   L L  A  L          
Sbjct: 303 NLDSFLD--LSSVISPFYIWLFIFIIQPHKEERFMYPIYPVLCLAAAIGLDMSLKLMIQI 360

Query: 433 QKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALT 468
                   +     +       Y +         L 
Sbjct: 361 LSSI-NETVRSKFPVRFVVLCVYAIIGCLSIARILA 395
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
           most likely an alpha 1,2 mannosyltransferase utilized
           for addition of the fourth, side-branching mannose onto
           the GPI core structure.; Smp3p [Saccharomyces
           cerevisiae]
 sp|Q04174|SMP3_YEAST SMP3 PROTEIN
 pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
 gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
 emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
          Length = 516

 Score =  303 bits (770), Expect = 5e-81
 Identities = 115/506 (22%), Positives = 183/506 (35%), Gaps = 117/506 (23%)

Query: 15  RHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRS 74
           R+    +   A+ L+L   P   Y+HPDE FQ +E++     +++ T  WEF +    RS
Sbjct: 3   RYQWWLYLVYAIGLMLCLGP--SYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60

Query: 75  I----VLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVV-FPRLIYTLISFSNDYCL 129
                ++   L  I  SF E         + + L     Y++ +  LI  LI        
Sbjct: 61  YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120

Query: 130 FRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVY 189
           F           ++   + +S++   + T TFSNS+E       L L+S   +  + V  
Sbjct: 121 F-----------MQKSLLLTSYVTWTYQTHTFSNSIET------LALISTLTVMEDMVNE 163

Query: 190 KKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTF--LLFGA 247
           K                          +   N ++ + +  I   GVFNR TF   +F  
Sbjct: 164 KN-------------------------IQRSNFKNSVILGLIFSFGVFNRVTFPAFIFLP 198

Query: 248 PMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHL 307
            ++ FW           +R      +L  L    +  LF+  D+  Y +           
Sbjct: 199 CLILFWKF---------YRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKG-------- 241

Query: 308 SIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRF 367
               FV TP N +K NL+      HG+HP Y HL+VN+P +   + L ++ +        
Sbjct: 242 ----FVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSG------- 290

Query: 368 FRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFS 427
                        +  L + AI   L FLS   HQE RFL+P+   L+            
Sbjct: 291 -----------YKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTN---------- 329

Query: 428 AKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADIS 487
                        L +  L S+  +       W + N+ +    G  HQAG+     D  
Sbjct: 330 -------------LNWTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYF 376

Query: 488 HVIATKPAATHVHLITSHIYSLPLHL 513
           H   T+    H   I    YS P  +
Sbjct: 377 HF-RTEQMGVH---IWWKTYSPPTWM 398
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
          Length = 516

 Score =  302 bits (767), Expect = 1e-80
 Identities = 116/506 (22%), Positives = 183/506 (35%), Gaps = 117/506 (23%)

Query: 15  RHLSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRS 74
           R+    +   A+ L+L   P   Y+HPDE FQ +E++     +++ T  WEF +    RS
Sbjct: 3   RYQWWLYLVYAIGLMLCLGP--SYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARS 60

Query: 75  I----VLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVV-FPRLIYTLISFSNDYCL 129
                ++   L  I  SF E         + + L     Y++ +  LI  LI        
Sbjct: 61  YGPLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQ 120

Query: 130 FRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVY 189
           F           I+   + +S++   + T TFSNS+E       L L+S   +  + V  
Sbjct: 121 F-----------IKKSLLLTSYVTWTYQTHTFSNSIET------LALISTLTVMEDMVNG 163

Query: 190 KKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTF--LLFGA 247
           K                          +   N ++ + +  I   GVFNR TF   +F  
Sbjct: 164 KN-------------------------IQRRNFKNSVILGLIFSFGVFNRVTFPAFIFLP 198

Query: 248 PMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHL 307
            ++ FW           +R      +L  L    +  LF+  D+  Y +           
Sbjct: 199 CLILFWKF---------YRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKG-------- 241

Query: 308 SIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRF 367
               FV TP N +K NL+      HG+HP Y HL+VN+P +   + L ++ +        
Sbjct: 242 ----FVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQILGPVLLLAIFSG------- 290

Query: 368 FRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFS 427
                        +  L + AI   L FLS   HQE RFL+P+   L+            
Sbjct: 291 -----------YKLDKLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTN---------- 329

Query: 428 AKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADIS 487
                        L +  L S+  +       W + N+ +    G  HQAG+     D  
Sbjct: 330 -------------LNWTPLSSTLVNKKIFKGTWLLFNIIMAFIMGISHQAGIIQFLGDYF 376

Query: 488 HVIATKPAATHVHLITSHIYSLPLHL 513
           H   T+    H   I    YS P  +
Sbjct: 377 HF-RTEQMGVH---IWWKTYSPPTWM 398
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
          Length = 554

 Score =  295 bits (748), Expect = 2e-78
 Identities = 73/509 (14%), Positives = 135/509 (26%), Gaps = 163/509 (32%)

Query: 73  RSIVLPFALLRIP----------------------------------------------- 85
           R  +L   +  +                                                
Sbjct: 53  RGDLLGENIYLLLFTLALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERL 112

Query: 86  --WSFYEFVAECLKAWWQLELLGTYAYVVFPRL---IYTLISFSNDYCLFRICRLYGLRF 140
             +++    A   K    L        +  PRL   + + ++    Y L +      +  
Sbjct: 113 RSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVAR 172

Query: 141 EIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDK 200
            +    +  SW      TRT +N++E  +    L                          
Sbjct: 173 WVFFCQL-CSWFTWYCCTRTLTNTMETVLTIIALF------------------------- 206

Query: 201 AESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGT 260
                           L      + +  S++       RPT +         W       
Sbjct: 207 -------------YYPLEGSKSMNSVKYSSLVALAFIIRPTAV-------ILWTPLLFRH 246

Query: 261 RSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFI 320
                R  +L +  F       L L +  D +++   TL +               +NF+
Sbjct: 247 FCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQ---------------FNFL 291

Query: 321 KANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQS 380
           K N+       +G HP + +     P++                L FF     + P+   
Sbjct: 292 KFNVLQNLGTFYGSHPWHWYFSQGFPVILG------------THLPFFIHGCYLAPKRYR 339

Query: 381 IVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLR 440
           I+ +        L   S+++H+E RF+ PV    ++     L    + K P         
Sbjct: 340 ILLVTVLWT---LLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKP--------- 387

Query: 441 LFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATKP------ 494
                           L   ++SN+ L L+ G +HQ G   + + I  V    P      
Sbjct: 388 ---------------ALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSAS 432

Query: 495 ----AATHVHLITSHIYSL-PLHLINIPS 518
                  H     SH++   P+  +  P 
Sbjct: 433 IFIMMPCHSTPYYSHVHCPLPMRFLQCPP 461
 Score =  161 bits (404), Expect = 4e-38
 Identities = 42/186 (22%), Positives = 69/186 (36%), Gaps = 28/186 (15%)

Query: 2   RLTTLWQN------RSPGDRHLSTYFC---FAAVRLLLVFVPQLGYVHPDEFFQSVEVMT 52
           R +TL+ N      R  GD      +      A+R+L  F+ Q  +V PDE++QS+EV  
Sbjct: 37  RKSTLYFNTQEKSARRRGDLLGENIYLLLFTLALRILNCFLVQTSFV-PDEYWQSLEVSH 95

Query: 53  GDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVV 112
              F      TWE+     +RS            ++    A   K    L        + 
Sbjct: 96  HMVFNY-GYLTWEWTER--LRSY-----------TYPLIFASIYKILHLLGKDSVQLLIW 141

Query: 113 FPRL---IYTLISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAM 169
            PRL   + + ++    Y L +      +   +    +  SW      TRT +N++E  +
Sbjct: 142 IPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQL-CSWFTWYCCTRTLTNTMETVL 200

Query: 170 CSWLLC 175
               L 
Sbjct: 201 TIIALF 206
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
 pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
           (EC 2.4.1.130) PIGB - human
 dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
          Length = 554

 Score =  293 bits (743), Expect = 1e-77
 Identities = 73/509 (14%), Positives = 135/509 (26%), Gaps = 163/509 (32%)

Query: 73  RSIVLPFALLRIP----------------------------------------------- 85
           R  +L   +  +                                                
Sbjct: 53  RGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERL 112

Query: 86  --WSFYEFVAECLKAWWQLELLGTYAYVVFPRL---IYTLISFSNDYCLFRICRLYGLRF 140
             +++    A   K    L        +  PRL   + + ++    Y L +      +  
Sbjct: 113 RSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVAR 172

Query: 141 EIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDK 200
            +    +  SW      TRT +N++E  +    L                          
Sbjct: 173 WVFFCQL-CSWFTWYCCTRTLTNTMETVLTIIALF------------------------- 206

Query: 201 AESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGT 260
                           L      + +  S++       RPT +         W       
Sbjct: 207 -------------YYPLEGSKSMNSVKYSSLVALAFIIRPTAV-------ILWTPLLFRH 246

Query: 261 RSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFI 320
                R  +L +  F       L L +  D +++   TL +               +NF+
Sbjct: 247 FCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQ---------------FNFL 291

Query: 321 KANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQS 380
           K N+       +G HP + +     P++                L FF     + P+   
Sbjct: 292 KFNVLQNWGTFYGSHPWHWYFSQGFPVILG------------THLPFFIHGCYLAPKRYR 339

Query: 381 IVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLR 440
           I+ +        L   S+++H+E RF+ PV    ++     L    + K P         
Sbjct: 340 ILLVTVLWT---LLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKP--------- 387

Query: 441 LFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATKP------ 494
                           L   ++SN+ L L+ G +HQ G   + + I  V    P      
Sbjct: 388 ---------------ALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSAS 432

Query: 495 ----AATHVHLITSHIYSL-PLHLINIPS 518
                  H     SH++   P+  +  P 
Sbjct: 433 IFIMMPCHSTPYYSHVHCPLPMRFLQCPP 461
 Score =  160 bits (403), Expect = 6e-38
 Identities = 42/186 (22%), Positives = 69/186 (36%), Gaps = 28/186 (15%)

Query: 2   RLTTLWQN------RSPGDRHLSTYFC---FAAVRLLLVFVPQLGYVHPDEFFQSVEVMT 52
           R +TL+ N      R  GD      +      A+R+L  F+ Q  +V PDE++QS+EV  
Sbjct: 37  RKSTLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFV-PDEYWQSLEVSH 95

Query: 53  GDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVV 112
              F      TWE+     +RS            ++    A   K    L        + 
Sbjct: 96  HMVFNY-GYLTWEWTER--LRSY-----------TYPLIFASIYKILHLLGKDSVQLLIW 141

Query: 113 FPRL---IYTLISFSNDYCLFRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAM 169
            PRL   + + ++    Y L +      +   +    +  SW      TRT +N++E  +
Sbjct: 142 IPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQL-CSWFTWYCCTRTLTNTMETVL 200

Query: 170 CSWLLC 175
               L 
Sbjct: 201 TIIALF 206
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
 sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
 pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
 emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
           (Swiss Prot accession number P38376)~cDNA EST yk549e12.3
           comes from this gene~cDNA EST yk618d6.3 comes from this
           gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
           yk618d6.5 comes from>
          Length = 653

 Score =  272 bits (690), Expect = 1e-71
 Identities = 59/428 (13%), Positives = 108/428 (24%), Gaps = 95/428 (22%)

Query: 1   MRLTTLWQNRSPGDRHLSTYFCFAAVRLLLVF-----VPQLGYVHPDEFFQSVEVMTGDH 55
           +++  L+   +  D      F F +V  +L+               DE +   E +    
Sbjct: 33  IKVEKLYHKANNPDN--DWPFSFGSVFKMLLSIRISGAIWGIINDCDEVYNYWEPLHLFL 90

Query: 56  FRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFYE-FVAECLKAWWQLELLGTYAYVVFP 114
           +  E  +TWE++    +RS                   A        L            
Sbjct: 91  YG-EGFQTWEYSPVYAIRSYF-----YIYLHYIPASLFAN-------LFGDTKIVVFTLI 137

Query: 115 RLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWL 173
           RL   L     +Y  F  IC+   +      +               FS        +  
Sbjct: 138 RLTIGLFCLLGEYYAFDAICKKINIATGRFFIL--------------FSIFSSGMFLAST 183

Query: 174 LCLVSECMLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICV 233
             + S   +          ++   Y            W                 + I  
Sbjct: 184 AFVPSSFCM------AITFYILGAYL--------NENWT----------------AGIFC 213

Query: 234 AGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLY 293
                  + ++         L        +        +       L    + +  DS Y
Sbjct: 214 VAF----STMVGWPFSAVLGLPIVADMLLLKGLRIRFILTSLV-IGLCIGGVQVITDSHY 268

Query: 294 YQHLTLGELHMMHLSIDNFVFTPWNFIKANLDS-AQTASHGVHPCYVHLMVNMPMLFNVL 352
           +                  V  P N    N+ S    + +G  P   + + N+   +N++
Sbjct: 269 FGKT---------------VLAPLNIFLYNVVSGPGPSLYGEEPLSFY-IKNLFNNWNIV 312

Query: 353 ALASLGAFAQLLLRFFRAEYQ------VLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRF 406
             A+   F   L  F +          +  RF  I+ L        L       H+E RF
Sbjct: 313 IFAAPFGFPLSLAYFTKVWMSQDRNVALYQRFAPIILLAV-TTAAWLLIFGSQAHKEERF 371

Query: 407 LLPVTFPL 414
           L P+   +
Sbjct: 372 LFPIYPFI 379
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein - Arabidopsis
           thaliana
 emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein [Arabidopsis
           thaliana]
          Length = 498

 Score =  269 bits (681), Expect = 2e-70
 Identities = 56/351 (15%), Positives = 95/351 (26%), Gaps = 70/351 (19%)

Query: 181 MLRTNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRP 240
              +  +     +       +       R W L                 I       RP
Sbjct: 149 ATWSTVLTIMGLYYWPCIRDSSIDYPVNRKWGLV----------------IAALACAIRP 192

Query: 241 TFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLG 300
           T  +         L  GM    +T       I          L      D L Y      
Sbjct: 193 TSAVIW-------LYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSW--- 242

Query: 301 ELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAF 360
                       V  P NF+K N  S+    +G HP + +      ++            
Sbjct: 243 ------------VIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVML----------- 279

Query: 361 AQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAP 420
                 F  A   +  + Q +    S  I   L   S++ H+E RF+LPV    ++    
Sbjct: 280 -FTFTPFSIAGI-IKSKNQKL----SALILWVLAIYSILGHKEFRFVLPVLPIALIFSGY 333

Query: 421 KL----ITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQ 476
                 ++G S+     K   + R  + K         Y       +N+ + L+    HQ
Sbjct: 334 AFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYF---LLATNIPMALYMSLFHQ 390

Query: 477 AGVYPLAADISHVIATKP-------AATHVHLITSHIY-SLPLHLINIPSS 519
            G       +S                 H     S ++ ++P+  ++   S
Sbjct: 391 RGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPS 441
 Score =  136 bits (341), Expect = 1e-30
 Identities = 31/136 (22%), Positives = 51/136 (36%), Gaps = 19/136 (13%)

Query: 20  YFCF-AAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLP 78
            F F  A R++   + Q  Y +PDE +QS+EV     F      TWE+     +RS + P
Sbjct: 41  IFLFCLAFRVVNALLIQT-YFNPDEHWQSLEVAHRTIFGY-GYMTWEW--KRGIRSYLHP 96

Query: 79  FALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYG- 137
                         A   K      L   Y  +  PRL+ ++ S   D  L+++      
Sbjct: 97  M-----------LFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYG 145

Query: 138 --LRFEIRLLAMGSSW 151
             +     +L +   +
Sbjct: 146 GNVATWSTVLTIMGLY 161
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
          Length = 512

 Score =  260 bits (659), Expect = 6e-68
 Identities = 66/450 (14%), Positives = 130/450 (28%), Gaps = 94/450 (20%)

Query: 102 LELLGTYAYVVFPRLIYTLISFSNDYCL-----------FRICRLYGLRFEIRL------ 144
           ++L+  +  ++  RL    +     Y +            ++   YG      +      
Sbjct: 1   MKLIYVFLLILAVRLASVFV--VQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSY 58

Query: 145 ---LAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKA 201
              L +   + +L          L+ A    +L  + +  L    V +   +   +    
Sbjct: 59  VYPLLIAGLYKILALLQ------LDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLAN 112

Query: 202 ESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTR 261
              +    I          +  +L   +       F RPT  +     +  + LR     
Sbjct: 113 TLEASLTTIALSYFPWYGESTAYLWPAAIC----CFLRPTAAVIWL-PLSLYHLRRSRQN 167

Query: 262 SITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIK 321
            +      L +  F L  L    L I  D+ ++                  + TP+ F+K
Sbjct: 168 VLE-----LILKRFVLIGLLVAGLGIAIDTYWHGQ---------------LIVTPYEFLK 207

Query: 322 ANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSI 381
            N+ +   + +G HP + +  V +P +  +           L   F   E         +
Sbjct: 208 YNIFNNIGSFYGSHPWHWYFSVGLPTVLGI---------NTLPFIFGVMETVKKSEKYPV 258

Query: 382 VSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRL 441
              +   IF+ L  LS + H+E RF+ P+    + +    L                   
Sbjct: 259 SKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDAL------------------S 300

Query: 442 FYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATKP------- 494
            +    SS       L I    NV    +   +HQ G   L   +  +            
Sbjct: 301 RWSIRASSTMLWTTALVILVG-NVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQA 359

Query: 495 -----AATHVHLITSHIY-SLPLHLINIPS 518
                   H     SHI+ ++ +  +    
Sbjct: 360 NILFLMPCHSTPYYSHIHQNVTMRFLTCEP 389
 Score =  100 bits (247), Expect = 1e-19
 Identities = 43/173 (24%), Positives = 63/173 (35%), Gaps = 41/173 (23%)

Query: 19  TYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLP 78
            +    AVRL  VFV Q  YV PDE++QS+EV     F      TWE+     +RS V  
Sbjct: 6   VFLLILAVRLASVFVVQTYYV-PDEYWQSLEVAHKLTFGY-GYLTWEWVQ--GIRSYV-- 59

Query: 79  FALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGL 138
                    +   +A   K    L+L   +  VV PR+                      
Sbjct: 60  ---------YPLLIAGLYKILALLQLDSAHLLVVLPRI---------------------- 88

Query: 139 RFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKK 191
             +  L  +   W     G+RT +N+LE ++ +  L   S       +  Y  
Sbjct: 89  -RKWALFLILVPWFWFYTGSRTLANTLEASLTTIAL---SYFPWYGESTAYLW 137
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
          Length = 457

 Score =  245 bits (619), Expect = 3e-63
 Identities = 109/395 (27%), Positives = 152/395 (37%), Gaps = 78/395 (19%)

Query: 134 RLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEF 193
              G      L  +  S++ LVF TRTFSN++E  + +WLL LVS  +    T       
Sbjct: 27  PAMGADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPT------- 79

Query: 194 LEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFW 253
                 K  +   R R W                +  I  AG FNRPTFL F    ++ W
Sbjct: 80  -----RKEPAPGPRWRSWL---------------LGGIVAAGFFNRPTFLAFAVVPLYLW 119

Query: 254 LLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFV 313
             RG     +          +    A     +F+  DS Y+                N V
Sbjct: 120 GTRGATNPGLKS--LTREALVLLPGATLTAAVFVATDSWYFSSPATSR---------NLV 168

Query: 314 FTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQ 373
            TP NF+  NL+    A HG H    HL VN  +LF VL   +L A  Q L    +A  Q
Sbjct: 169 LTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGLQASAQ 228

Query: 374 V-LPRFQSIVSLMSGA-------IFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITG 425
           + L R     SL+S          F+PL  LS  +HQE RFL+P+  PL+LL +P+    
Sbjct: 229 MGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSPQ---- 284

Query: 426 FSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGV---YPL 482
            +   P++                            + N    L FG +HQ G+      
Sbjct: 285 -TQPVPWKGTV------------------------ALFNALGALLFGCLHQGGLVPGLEY 319

Query: 483 AADISHVIATKPAATHVHLITSHIYSLPLHLINIP 517
              + H        TH  L+ +H Y  P HL+++P
Sbjct: 320 LEQVVHAPVLPSTPTHYTLLFTHTYMPPRHLLHLP 354
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
          Length = 611

 Score =  234 bits (592), Expect = 4e-60
 Identities = 55/281 (19%), Positives = 81/281 (28%), Gaps = 41/281 (14%)

Query: 229 STICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-DFNLRIALFCLCALPALVLFI 287
           ++I V GV      +L         L        +  R       +L  L      V  +
Sbjct: 212 TSIAVLGVA--AGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALILFLVPV--V 267

Query: 288 FCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSA-QTASHGVHPCYVHLMVNMP 346
             DS YY                  V  P N +  N+ +      +G  P Y +L+    
Sbjct: 268 VIDSYYYGK---------------LVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGF- 311

Query: 347 MLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVS-----LMSGAIFVPLFFLSLINH 401
                L      A A L+L        +L RF          L    +++      +  H
Sbjct: 312 -----LNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPH 366

Query: 402 QEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWY 461
           +E RFL PV   + L  A  L +     Y F      L   Y    +  A G   L    
Sbjct: 367 KEERFLFPVYPLICLCGAVAL-SALQKCYHFVFQRYRL-EHYTVTSNWLALGTVFLFGLL 424

Query: 462 VSNVALTLFFGFIHQAGVYPLAADISHVIATKPAAT-HVHL 501
             + ++ LF G+    G   L              T H   
Sbjct: 425 SFSRSVALFRGY---HGPLDL---YPEFYRIATDPTIHTVP 459
 Score =  197 bits (496), Expect = 7e-49
 Identities = 41/270 (15%), Positives = 78/270 (28%), Gaps = 64/270 (23%)

Query: 30  LVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFY 89
           L           DE F   E      +  E  +TWE++ +  +RS         +  ++ 
Sbjct: 70  LCAALLSNISDCDETFNYWEPTHYLIYG-EGFQTWEYSPAYAIRSY-----AYLLLHAWP 123

Query: 90  EFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMG 148
              A   +     ++L  Y      R +   +S   +   ++ +C+ +GL     +  M 
Sbjct: 124 A--AFHARILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLH----VSRMM 173

Query: 149 SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESISERV 208
            ++++L               CS    L S   + T  +     ++++            
Sbjct: 174 LAFLVLST----------GMFCSSSAFLPSSFCMYTTLIAMTGWYMDK------------ 211

Query: 209 RIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-D 267
                               ++I V GV      +L         L        +  R  
Sbjct: 212 --------------------TSIAVLGVA--AGAILGWPFSAALGLPIAFDLLVMKHRWK 249

Query: 268 FNLRIALFCLCALPALVLFIFCDSLYYQHL 297
                +L  L      V  +  DS YY  L
Sbjct: 250 SFFHWSLMALILFLVPV--VVIDSYYYGKL 277
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
          Length = 618

 Score =  233 bits (590), Expect = 7e-60
 Identities = 55/286 (19%), Positives = 83/286 (28%), Gaps = 44/286 (15%)

Query: 229 STICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-DFNLRIALFCLCALPALVLFI 287
           ++I V GV      +L         L        +  R       +L  L      V  +
Sbjct: 212 TSIAVLGVA--AGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALILFLVPV--V 267

Query: 288 FCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSA-QTASHGVHPCYVHLMVNMP 346
             DS YY                  V  P N +  N+ +      +G  P Y +L+    
Sbjct: 268 VIDSYYYGK---------------LVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLINGF- 311

Query: 347 MLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVS-----LMSGAIFVPLFFLSLINH 401
                L      A A L+L        +L RF          L    +++      +  H
Sbjct: 312 -----LNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPH 366

Query: 402 QEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRL-----FYDKLLSSKASGPYL 456
           +E RFL PV   + L  A  L     +   FQK +  +        Y    +  A G   
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVF 426

Query: 457 LKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATKPAAT-HVHL 501
           L      + ++ LF G+    G   L              T H   
Sbjct: 427 LFGLLSFSRSVALFRGY---HGPLDL---YPEFYRIATDPTIHTVP 466
 Score =  196 bits (494), Expect = 1e-48
 Identities = 41/270 (15%), Positives = 78/270 (28%), Gaps = 64/270 (23%)

Query: 30  LVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFY 89
           L           DE F   E      +  E  +TWE++ +  +RS         +  ++ 
Sbjct: 70  LCAALLSNISDCDETFNYWEPTHYLIYG-EGFQTWEYSPAYAIRSY-----AYLLLHAWP 123

Query: 90  EFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMG 148
              A   +     ++L  Y      R +   +S   +   ++ +C+ +GL     +  M 
Sbjct: 124 A--AFHARILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLH----VSRMM 173

Query: 149 SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESISERV 208
            ++++L               CS    L S   + T  +     ++++            
Sbjct: 174 LAFLVLST----------GMFCSSSAFLPSSFCMYTTLIAMTGWYMDK------------ 211

Query: 209 RIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-D 267
                               ++I V GV      +L         L        +  R  
Sbjct: 212 --------------------TSIAVLGVA--AGAILGWPFSAALGLPIAFDLLVMKHRWK 249

Query: 268 FNLRIALFCLCALPALVLFIFCDSLYYQHL 297
                +L  L      V  +  DS YY  L
Sbjct: 250 SFFHWSLMALILFLVPV--VVIDSYYYGKL 277
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
          Length = 611

 Score =  233 bits (590), Expect = 7e-60
 Identities = 55/281 (19%), Positives = 81/281 (28%), Gaps = 41/281 (14%)

Query: 229 STICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-DFNLRIALFCLCALPALVLFI 287
           ++I V GV      +L         L        +  R       +L  L      V  +
Sbjct: 212 TSIAVLGVA--AGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALILFLVPV--V 267

Query: 288 FCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSA-QTASHGVHPCYVHLMVNMP 346
             DS YY                  V  P N +  N+ +      +G  P Y +L+    
Sbjct: 268 VIDSYYYGK---------------LVIAPLNIVLYNVFTPHGPDLYGTEPWYFYLIKGF- 311

Query: 347 MLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVS-----LMSGAIFVPLFFLSLINH 401
                L      A A L+L        +L RF          L    +++      +  H
Sbjct: 312 -----LNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPH 366

Query: 402 QEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWY 461
           +E RFL PV   + L  A  L +     Y F      L   Y    +  A G   L    
Sbjct: 367 KEERFLFPVYPLICLCGAVAL-SALQKCYHFVFQRYRL-EHYTVTSNWLALGTVFLFGLL 424

Query: 462 VSNVALTLFFGFIHQAGVYPLAADISHVIATKPAAT-HVHL 501
             + ++ LF G+    G   L              T H   
Sbjct: 425 SFSRSVALFRGY---HGPLDL---YPEFYRIATDPTIHTVP 459
 Score =  155 bits (390), Expect = 2e-36
 Identities = 26/168 (15%), Positives = 57/168 (33%), Gaps = 27/168 (16%)

Query: 30  LVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFY 89
           L           DE F   E      +  E  +TWE++ +  +RS         +  ++ 
Sbjct: 70  LCAALLSNISDCDETFNYWEPTHYLIYG-EGFQTWEYSPAYAIRSY-----AYLLLHAWP 123

Query: 90  EFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMG 148
              A   +     ++L  Y      R +   +S   +   ++ +C+ +GL     +  M 
Sbjct: 124 A--AFHARILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLH----VSRMM 173

Query: 149 SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEE 196
            ++++L               CS    L S   + T  +     ++++
Sbjct: 174 LAFLVLST----------GMFCSSSAFLPSSFCMYTTLIAMTGWYMDK 211
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
           lipid-linked oligosaccharides; Alg9p [Saccharomyces
           cerevisiae]
 sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
 pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
 emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
          Length = 555

 Score =  232 bits (588), Expect = 1e-59
 Identities = 73/478 (15%), Positives = 128/478 (26%), Gaps = 121/478 (25%)

Query: 27  RLLLVFVPQLG-------YVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPF 79
            LLL+F+ ++            DE F   E +          +TWE++    +RS     
Sbjct: 10  LLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGF-GKQTWEYSPEYSIRSWAFLL 68

Query: 80  ALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGLR 139
               I +   +F            L   +      R      SF  +         + L 
Sbjct: 69  PFYCILYPVNKFTD----------LESHWN-FFITRACLGFFSFIME---------FKLH 108

Query: 140 FEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYD 199
            EI                               L L    +     +     F      
Sbjct: 109 REIA----------------------------GSLALQIANIWIIFQLFNPGWFHASVEL 140

Query: 200 KAES-----ISERVRIWKLKNSL-PAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFW 253
              +          R      S     N    +A + +           +L    ++   
Sbjct: 141 LPSAVAMLLYVGATRHSLRYLSTGSTSNFTKSLAYNFLA---------SILGWPFVLILS 191

Query: 254 LLRGMGTRSITFRDFNLRIALF--CLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDN 311
           L           R  +     F  CL         I  DS++Y  L              
Sbjct: 192 LPLC-LHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAP------------ 238

Query: 312 FVFTPWNFIKANLDS----AQTASHGVHPCYVH-LMVNMPMLFNVLALASLGAFAQLLLR 366
                WN +  N+ +    +     GV P Y + L + +     VL LA LG F   L  
Sbjct: 239 ---VSWNILFYNVINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHLRLWP 295

Query: 367 FFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGF 426
            +                   ++F  +   +   H+E RFL P+   + L  +       
Sbjct: 296 LW------------------ASLFTWIAVFTQQPHKEERFLYPIYGLITLSASIAFYKVL 337

Query: 427 SAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSN---VALTLF--FGFIHQAGV 479
           +         P+L+      +    +G  + +I  + N     + ++  F  ++Q GV
Sbjct: 338 NLF----NRKPILKKGIKLSVLLIVAGQAMSRIVALVNNYTAPIAVYEQFSSLNQGGV 391
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
           mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
 dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
          Length = 618

 Score =  232 bits (587), Expect = 2e-59
 Identities = 55/286 (19%), Positives = 83/286 (28%), Gaps = 44/286 (15%)

Query: 229 STICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-DFNLRIALFCLCALPALVLFI 287
           ++I V GV      +L         L        +  R       +L  L      V  +
Sbjct: 212 TSIAVLGVA--AGAILGWPFSAALGLPIAFDLLVMKHRWKSFFHWSLMALILFLVPV--V 267

Query: 288 FCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSA-QTASHGVHPCYVHLMVNMP 346
             DS YY                  V  P N +  N+ +      +G  P Y +L+    
Sbjct: 268 VIDSYYYGK---------------LVIAPLNIVLYNIFTPHGPDLYGTEPWYFYLINGF- 311

Query: 347 MLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVS-----LMSGAIFVPLFFLSLINH 401
                L      A A L+L        +L RF          L    +++      +  H
Sbjct: 312 -----LNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPH 366

Query: 402 QEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRL-----FYDKLLSSKASGPYL 456
           +E RFL PV   + L  A  L     +   FQK +  +        Y    +  A G   
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVF 426

Query: 457 LKIWYVSNVALTLFFGFIHQAGVYPLAADISHVIATKPAAT-HVHL 501
           L      + ++ LF G+    G   L              T H   
Sbjct: 427 LFGLLSFSRSVALFRGY---HGPLDL---YPEFYRIATDPTIHTVP 466
 Score =  155 bits (388), Expect = 3e-36
 Identities = 26/168 (15%), Positives = 57/168 (33%), Gaps = 27/168 (16%)

Query: 30  LVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFY 89
           L           DE F   E      +  E  +TWE++ +  +RS         +  ++ 
Sbjct: 70  LCAALLSNISDCDETFNYWEPTHYLIYG-EGFQTWEYSPAYAIRSY-----AYLLLHAWP 123

Query: 90  EFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMG 148
              A   +     ++L  Y      R +   +S   +   ++ +C+ +GL     +  M 
Sbjct: 124 A--AFHARILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLH----VSRMM 173

Query: 149 SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEE 196
            ++++L               CS    L S   + T  +     ++++
Sbjct: 174 LAFLVLST----------GMFCSSSAFLPSSFCMYTTLIAMTGWYMDK 211
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
           musculus]
          Length = 611

 Score =  225 bits (569), Expect = 2e-57
 Identities = 56/281 (19%), Positives = 82/281 (28%), Gaps = 41/281 (14%)

Query: 229 STICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-DFNLRIALFCLCALPALVLFI 287
           + I V GV      +L         L       +   R    L  +L  L      V  +
Sbjct: 212 TPIAVLGVA--AGAILGWPFSAALGLPIAFDLLARKHRWKSFLLWSLVALALFLVPV--V 267

Query: 288 FCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSA-QTASHGVHPCYVHLMVNMP 346
             DS YY                  V  P N +  N+ ++     +G  P Y +L+    
Sbjct: 268 VIDSYYYGK---------------LVVAPLNIVLYNVFTSHGPDLYGTEPWYFYLINGF- 311

Query: 347 MLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVS-----LMSGAIFVPLFFLSLINH 401
                L      A A L+L        +L RF          L    +++      +  H
Sbjct: 312 -----LNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPH 366

Query: 402 QEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWY 461
           +E RFL PV   + L  A  L +     Y F      L   Y    +  A G   L    
Sbjct: 367 KEERFLFPVYPLICLCGAVAL-SALQKCYHFVFQRYRL-EHYTVTSNWLALGTVFLFGLL 424

Query: 462 VSNVALTLFFGFIHQAGVYPLAADISHVIATKPAAT-HVHL 501
             + ++ LF G+    G   L              T H   
Sbjct: 425 SFSRSVALFRGY---HGPLDL---YPEFYRIATDPTIHTVP 459
 Score =  188 bits (475), Expect = 3e-46
 Identities = 41/270 (15%), Positives = 77/270 (28%), Gaps = 64/270 (23%)

Query: 30  LVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFY 89
           L           DE F   E      +  +  +TWE++    +RS         +  ++ 
Sbjct: 70  LCAALLSNISDCDETFNYWEPTHYLIYG-KGFQTWEYSPVYAIRSY-----AYLLLHAWP 123

Query: 90  EFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMG 148
              A   +     ++L  Y      R +   +S   +   ++ +C+ +GL     +  M 
Sbjct: 124 A--AFHARILQTNKILVFYFL----RCLLAFVSCVCELYFYKAVCKKFGLH----VSRMM 173

Query: 149 SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESISERV 208
            ++++L               CS    L S   + T  +     ++++            
Sbjct: 174 LAFLVLST----------GMFCSSSAFLPSSFCMYTTLIAMTGWYMDK------------ 211

Query: 209 RIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR-D 267
                               + I V GV      +L         L       +   R  
Sbjct: 212 --------------------TPIAVLGVA--AGAILGWPFSAALGLPIAFDLLARKHRWK 249

Query: 268 FNLRIALFCLCALPALVLFIFCDSLYYQHL 297
             L  +L  L      V  +  DS YY  L
Sbjct: 250 SFLLWSLVALALFLVPV--VVIDSYYYGKL 277
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
           chromosome I precursor [Leishmania major]
          Length = 822

 Score =  195 bits (492), Expect = 2e-48
 Identities = 45/340 (13%), Positives = 92/340 (26%), Gaps = 64/340 (18%)

Query: 38  YVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFYEFVAECLK 97
               DE F  +E +    +     +TWE  +   +RS +          ++       ++
Sbjct: 31  ISDCDETFNFIEPIHYLLYG-SGKQTWEVCSRFALRSWLF-----LWIHAWPVV---LIR 81

Query: 98  AWWQLELLGTYAYVVFPRLIYTLISFSNDYCL-----FRICRLYGL-------------R 139
               L  +  Y Y+   R++    +   +        F +                    
Sbjct: 82  GAASLSSVRVYFYL---RMLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLLANYPIQH 138

Query: 140 FEIRLL----AMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLE 195
             + +L    AM  ++++L    RT S +   A+ S +    ++  +        +  + 
Sbjct: 139 AAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLSRVGDRPTQNTMPAAAAGTAQLSMM 198

Query: 196 EKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLL 255
                    S         +S    +         I  A  F+    +           L
Sbjct: 199 VP------PSPSSAPTLHSSSASPPSAPPRHLCWFIGAALCFSVLAVVTGWPFAALISAL 252

Query: 256 RGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFT 315
            G+         F +R     L +L      +F                       +  +
Sbjct: 253 VGLDLLL----RFPVRTLACTLGSLLVACAAVF--------------VADVRYYCRWTLS 294

Query: 316 PWNFIKANLDSA---QTASHGVHPCYVH---LMVNMPMLF 349
            WN +  N            GV P +     LM+N  ++F
Sbjct: 295 SWNVVMYNGFGGSGRGPELFGVEPIFFFWKNLMLNFHLMF 334
 Score = 42.5 bits (99), Expect = 0.027
 Identities = 12/40 (30%), Positives = 16/40 (40%)

Query: 383 SLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKL 422
            L     FV   F   I H+E RF+ P    ++L     L
Sbjct: 436 LLHIMPFFVWFLFWMSIAHKEERFMSPAYPFMLLAATRTL 475
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
          Length = 919

 Score =  186 bits (469), Expect = 1e-45
 Identities = 32/283 (11%), Positives = 77/283 (26%), Gaps = 39/283 (13%)

Query: 212 KLKNSLPAHNLQHLMAMSTI-----CVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR 266
                         ++   +      +A   +    +L     +  +L   + +    F+
Sbjct: 525 TSFLPSSFSMYAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSLVKRFK 584

Query: 267 DFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDS 326
                        L    + +  D  YY+  T                   N +  N+  
Sbjct: 585 QAF-IAGAVTTIFLL--GVSLLVDYYYYKRWTSSV---------------LNLLIYNVLG 626

Query: 327 AQ-TASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLM 385
              +  +G      ++            LA L      ++R          ++   + ++
Sbjct: 627 GGESHLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIR---------RKYDRALLVV 677

Query: 386 SGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDK 445
              +++ L F+SL  H+E RFL P+   + +  +  +                L +   K
Sbjct: 678 ISPMYIWLAFMSLQPHKEERFLYPIYPLICVSASAVIENIPELFREKYSSRESLLVTITK 737

Query: 446 LLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISH 488
            +     G     +    +    L  G+   +    +   + H
Sbjct: 738 YMRPVILGCI---LCASHSRTFALINGY---SAPLEVYKLLEH 774
 Score =  147 bits (368), Expect = 7e-34
 Identities = 46/237 (19%), Positives = 74/237 (30%), Gaps = 39/237 (16%)

Query: 10  RSPG----DRHLSTYFCFAAVRLLLVFVPQLGYVH-PDEFFQSVEVMTGDHFRLEHTRTW 64
           RS G    D  L  +  F A+  L         +H  DE F   E +    ++    +TW
Sbjct: 382 RSNGGDAEDGGLRWFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPLHYILYK-SGFQTW 440

Query: 65  EFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFS 124
           E++++  +RS +       +     E        W               RL   L+S  
Sbjct: 441 EYSSNFALRSYL-----YILFH---ELAGRPASWW---FGDDKVRVFYAVRLFLGLVSAV 489

Query: 125 NDYCL-FRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLR 183
           +D  L   + R YG R     +AM                       +    L S   + 
Sbjct: 490 SDTVLVVALSRKYGKRIATYAVAMLCL--------------TSGCFFASTSFLPSSFSMY 535

Query: 184 TNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPA------HNLQHLMAMSTICVA 234
             ++      L EKY  A ++S    I     S+ A      ++L      + I  A
Sbjct: 536 AISLS-SGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSLVKRFKQAFIAGA 591
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
          Length = 570

 Score =  174 bits (439), Expect = 4e-42
 Identities = 32/283 (11%), Positives = 77/283 (26%), Gaps = 39/283 (13%)

Query: 212 KLKNSLPAHNLQHLMAMSTI-----CVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFR 266
                         ++   +      +A   +    +L     +  +L   + +    F+
Sbjct: 176 TSFLPSSFSMYAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSLVKRFK 235

Query: 267 DFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDS 326
                        L    + +  D  YY+  T                   N +  N+  
Sbjct: 236 QAF-IAGAVTTIFLL--GVSLLVDYYYYKRWTSSV---------------LNLLIYNVLG 277

Query: 327 AQ-TASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLM 385
              +  +G      ++            LA L      ++R          ++   + ++
Sbjct: 278 GGESHLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIR---------RKYDRALLVV 328

Query: 386 SGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDK 445
              +++ L F+SL  H+E RFL P+   + +  +  +                L +   K
Sbjct: 329 ISPMYIWLAFMSLQPHKEERFLYPIYPLICVSASAVIENIPELFREKYSSRESLLVTITK 388

Query: 446 LLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLAADISH 488
            +     G     +    +    L  G+   +    +   + H
Sbjct: 389 YMRPVILGCI---LCASHSRTFALINGY---SAPLEVYKLLEH 425
 Score =  137 bits (342), Expect = 9e-31
 Identities = 46/237 (19%), Positives = 74/237 (30%), Gaps = 39/237 (16%)

Query: 10  RSPG----DRHLSTYFCFAAVRLLLVFVPQLGYVH-PDEFFQSVEVMTGDHFRLEHTRTW 64
           RS G    D  L  +  F A+  L         +H  DE F   E +    ++    +TW
Sbjct: 33  RSNGGDAEDGGLRWFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPLHYILYK-SGFQTW 91

Query: 65  EFNNSLPVRSIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFS 124
           E++++  +RS +       +     E        W               RL   L+S  
Sbjct: 92  EYSSNFALRSYL-----YILFH---ELAGRPASWW---FGDDKVRVFYAVRLFLGLVSAV 140

Query: 125 NDYCL-FRICRLYGLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLR 183
           +D  L   + R YG R     +AM                       +    L S   + 
Sbjct: 141 SDTVLVVALSRKYGKRIATYAVAMLCL--------------TSGCFFASTSFLPSSFSMY 186

Query: 184 TNTVVYKKEFLEEKYDKAESISERVRIWKLKNSLPA------HNLQHLMAMSTICVA 234
             ++      L EKY  A ++S    I     S+ A      ++L      + I  A
Sbjct: 187 AISLS-SGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSLVKRFKQAFIAGA 242
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
          Length = 278

 Score =  145 bits (364), Expect = 3e-33
 Identities = 32/191 (16%), Positives = 62/191 (31%), Gaps = 38/191 (19%)

Query: 345 MPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEP 404
           +P++      A        L +    +  + P FQ  +      I + L   S + H+E 
Sbjct: 2   LPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKL-----TILLNLLVYSTLPHKEF 56

Query: 405 RFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSN 464
           RF+ P+    IL+ +  L+              L R ++ +L   K+    +       +
Sbjct: 57  RFIFPLQPLFILISSFGLLR-------------LDRDYWKRLSGLKSLLWLVPF----VS 99

Query: 465 VALTLFFGFIHQAGVYPLAADISHVIATKP----AATHVHL------------ITSHIYS 508
           V + L     H++G   +   +               H               + S   +
Sbjct: 100 VFIALLLDTFHESGSIEVMKFLHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCN 159

Query: 509 LPLHLINIPSS 519
            PLHL+  P +
Sbjct: 160 PPLHLLGDPEA 170
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
          Length = 198

 Score =  137 bits (344), Expect = 5e-31
 Identities = 23/154 (14%), Positives = 49/154 (30%), Gaps = 27/154 (17%)

Query: 30  LVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRIPWSFY 89
           L           DE F   E      +  E  +TWE++ +  +RS         +  ++ 
Sbjct: 70  LCAALLSNISDCDETFNYWEPTHYLIYG-EGFQTWEYSPAYAIRSY-----AYLLLHAWP 123

Query: 90  EFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFEIRLLAMG 148
              A   +     ++L  Y      R +   +S   +   ++ +C+ +GL     +  M 
Sbjct: 124 A--AFHARILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLH----VSRMM 173

Query: 149 SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECML 182
            ++++L               CS  +        
Sbjct: 174 LAFLVLST----------GMFCSSSVYPSPLICW 197
>gb|AAF55584.1| (AE003723) CG7709 gene product [Drosophila melanogaster]
          Length = 950

 Score =  118 bits (293), Expect = 5e-25
 Identities = 47/159 (29%), Positives = 66/159 (40%), Gaps = 11/159 (6%)

Query: 678 RNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAG-FIASPVTTYAAAPAYAAS 736
             +P   S +Y   +P    +              A + +    A+P ++Y A    + S
Sbjct: 283 APRPAAPSSSYGAPAPPSSSYGAPAAPSSSYGAPAAPSSSYGAPAAPSSSYGAPAPPSKS 342

Query: 737 YAAPVAYS-------APVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPA--- 786
           Y AP   S       AP  +Y A AP  S+Y A AP  S+Y A AP   +Y A AP    
Sbjct: 343 YGAPAPPSSSYGAPAAPSKSYGAPAPPSSSYGAPAPPSSSYGAPAPPSPSYGAPAPPSKS 402

Query: 787 YTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSP 825
           Y A    + +Y AP     +  A A P ++Y APA  S 
Sbjct: 403 YGAPAPPSSSYGAPAAPSKSYGAPAPPSSSYGAPAPPSS 441
 Score =  103 bits (256), Expect = 1e-20
 Identities = 44/154 (28%), Positives = 62/154 (39%), Gaps = 8/154 (5%)

Query: 679 NKPRYVSLAYSGCSPTKGYFLLFIQFLICL--ALCIAAAQAGFIASPVTTYAAAP--AYA 734
              R  S +Y    P                       +Q+    +P ++    P  A +
Sbjct: 219 PHHRRPSSSYGAPRPAPPSQSYGAPPSASYGPPKSAPPSQSYGAPAPPSSKYGPPKSAPS 278

Query: 735 ASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPA---YTASV 791
           +SY AP    AP ++Y A AP  S+Y A A   S+Y A A   S+Y A A     Y A  
Sbjct: 279 SSYGAPRPA-APSSSYGAPAPPSSSYGAPAAPSSSYGAPAAPSSSYGAPAAPSSSYGAPA 337

Query: 792 YSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSP 825
             + +Y AP    ++  A AAP  +Y APA  S 
Sbjct: 338 PPSKSYGAPAPPSSSYGAPAAPSKSYGAPAPPSS 371
>gb|AAF48706.1| (AE003504) CG5095 gene product [Drosophila melanogaster]
          Length = 576

 Score =  114 bits (283), Expect = 8e-24
 Identities = 43/149 (28%), Positives = 60/149 (39%), Gaps = 13/149 (8%)

Query: 685 SLAYSGCSPTKGYFLLFIQFLICLALCIA-AAQAGFIASPVTTYAAA---PAYAASYAAP 740
           + + +  +      + +      +       A +    +P  TY+A    PA   S  AP
Sbjct: 148 ASSSASANSYSAPSVSYSAPAPAVTYSAPAPAVSYSAPAPAVTYSAPAPAPAVTYSAPAP 207

Query: 741 V--AYSAPVATYAAAAP-AYSTYAAAAPAY---STYAAAAPAYSTYAAAAPAYTASVYSA 794
           V    +AP  TY+A AP    TY+A APA     +  A AP     AA A  Y+A   + 
Sbjct: 208 VVRVQAAPAVTYSAPAPAPAVTYSAPAPAPAVTYSAPAPAPVVRVQAAPAVTYSAPAPAV 267

Query: 795 PAYTAPVTTYAAGAAYAAPVTTYSAPAIV 823
              T      A   +  AP  TYSAPA V
Sbjct: 268 ---TYSAPAPAVTYSGPAPAVTYSAPAPV 293
 Score =  109 bits (272), Expect = 2e-22
 Identities = 47/161 (29%), Positives = 60/161 (37%), Gaps = 40/161 (24%)

Query: 672 YEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA- 730
           Y            ++ YS  +P                     A +    +P  TY+A  
Sbjct: 164 YSAPA-------PAVTYSAPAP---------------------AVSYSAPAPAVTYSAPA 195

Query: 731 --PAYAASYAAPV--AYSAPVATYAAAAP-AYSTYAAAAPAY---STYAAAAPAYSTYAA 782
             PA   S  APV    +AP  TY+A AP    TY+A APA     +  A AP     AA
Sbjct: 196 PAPAVTYSAPAPVVRVQAAPAVTYSAPAPAPAVTYSAPAPAPAVTYSAPAPAPVVRVQAA 255

Query: 783 AAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIV 823
            A  Y+A   +    T      A   +  AP  TYSAPA V
Sbjct: 256 PAVTYSAPAPAV---TYSAPAPAVTYSGPAPAVTYSAPAPV 293
 Score =  101 bits (250), Expect = 6e-20
 Identities = 44/153 (28%), Positives = 56/153 (35%), Gaps = 33/153 (21%)

Query: 672 YEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAP 731
           Y            +++YS  +P     + +           A A      +PV    AAP
Sbjct: 173 YSAPA-------PAVSYSAPAP----AVTYSAPAP------APAVTYSAPAPVVRVQAAP 215

Query: 732 AYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTAS 790
           A   S  AP    AP  TY+A AP    TY+A A         AP     AA A  Y+A 
Sbjct: 216 AVTYSAPAP----APAVTYSAPAPAPAVTYSAPA--------PAPVVRVQAAPAVTYSAP 263

Query: 791 VYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIV 823
             +    T      A   +  AP  TYSAPA V
Sbjct: 264 APAV---TYSAPAPAVTYSGPAPAVTYSAPAPV 293
 Score = 94.7 bits (233), Expect = 5e-18
 Identities = 42/141 (29%), Positives = 54/141 (37%), Gaps = 8/141 (5%)

Query: 688 YSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA-PAYAASYAAPVAYSAP 746
           YS  + +      +    +      A A      +P  +Y+A  PA   S  AP    AP
Sbjct: 144 YSSSASSSASANSYSAPSVSY-SAPAPAVTYSAPAPAVSYSAPAPAVTYSAPAP----AP 198

Query: 747 VATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYA-AAAPAYTASVYSAPAYTAPVTTYA 805
             TY+A AP     AA A    +  A APA +  A A APA T S  +           A
Sbjct: 199 AVTYSAPAPVVRVQAAPAV-TYSAPAPAPAVTYSAPAPAPAVTYSAPAPAPVVRVQAAPA 257

Query: 806 AGAAYAAPVTTYSAPAIVSPI 826
              +  AP  TYSAPA     
Sbjct: 258 VTYSAPAPAVTYSAPAPAVTY 278
 Score = 81.1 bits (198), Expect = 7e-14
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 10/109 (9%)

Query: 675 DVTRNKPRYV-SLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA-PA 732
            VT + P    ++ YS  +P              + +  A A      +P  TY+A  PA
Sbjct: 216 AVTYSAPAPAPAVTYSAPAPAPAVTYSAPAPAPVVRVQAAPAVTYSAPAPAVTYSAPAPA 275

Query: 733 YAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTY 780
              S  AP        TY+A AP     Y+A APA  +Y A AP     
Sbjct: 276 VTYSGPAPAV------TYSAPAPVPVVRYSAPAPAPISY-APAPVSYAP 317
 Score = 79.5 bits (194), Expect = 2e-13
 Identities = 45/156 (28%), Positives = 54/156 (33%), Gaps = 26/156 (16%)

Query: 684 VSLAY------------SGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA- 730
            S +Y               S +                  A A      +P  +Y+A  
Sbjct: 127 PSYSYGRSSGYGGNYGGYSSSASSSASANSYSAPSVSYSAPAPAVTYSAPAPAVSYSAPA 186

Query: 731 PAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTAS 790
           PA   S  AP    AP  TY+A AP     AA A    TY+A APA +   +A     A 
Sbjct: 187 PAVTYSAPAP----APAVTYSAPAPVVRVQAAPAV---TYSAPAPAPAVTYSAPAPAPAV 239

Query: 791 VYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPI 826
            YSAPA              AAP  TYSAPA     
Sbjct: 240 TYSAPAPA------PVVRVQAAPAVTYSAPAPAVTY 269
 Score = 34.3 bits (78), Expect = 7.3
 Identities = 12/80 (15%), Positives = 17/80 (21%), Gaps = 4/80 (5%)

Query: 672 YEID---VTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYA 728
           Y      VT + P   ++ YS  +P                     + A    S      
Sbjct: 269 YSAPAPAVTYSGPAP-AVTYSAPAPVPVVRYSAPAPAPISYAPAPVSYAPQPQSQQVVKT 327

Query: 729 AAPAYAASYAAPVAYSAPVA 748
                    A    Y  P  
Sbjct: 328 IKLIVDEDRAPAQVYGPPAV 347
>gb|AAF48345.1| (AE003495) CG11584 gene product [Drosophila melanogaster]
          Length = 1015

 Score =  113 bits (280), Expect = 2e-23
 Identities = 47/173 (27%), Positives = 60/173 (34%), Gaps = 22/173 (12%)

Query: 675 DVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA-PAY 733
            V +         YS  +   GY   +    +       A           TY A   A 
Sbjct: 811 AVVKTYSAPAVSTYSAPA-VSGYSQTYTAPAVVKTYSAPAVSTYTAPVVTKTYTAPVVAK 869

Query: 734 AASYAAPVAYSAPVA--TYAAA-------APAYSTYAAAAPAYSTYA------AAAPAYS 778
             +  A   Y+APV   TY A        APA STY+A A +  T         A     
Sbjct: 870 TYTAPAVSTYTAPVVAKTYTAPAVVKTYSAPAVSTYSAPAVSTYTAPVVTKTYTAPVVTK 929

Query: 779 TYAAAAPAYTASVYSAPAYTAP----VTTYAAGAAYAAP-VTTYSAPAIVSPI 826
           TY A A   T S  +   YTAP     T       Y+AP V+TY+AP +    
Sbjct: 930 TYTAPAVVKTYSAPAVSTYTAPAVSTYTAPVVAKTYSAPAVSTYTAPVVTKTY 982
 Score = 68.6 bits (166), Expect = 4e-10
 Identities = 39/165 (23%), Positives = 49/165 (29%), Gaps = 18/165 (10%)

Query: 677 TRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAAS 736
                    L YS  +P            +      A A A          A APA   +
Sbjct: 273 AAPVQAVQQLTYSAPAPVTQEQYYSAPASVVQQTSSAPAPAPAPVQEQFYSAPAPAIQQT 332

Query: 737 YAAPVAYSAPVATYAAAAP-AYSTYAAAAPA---------YSTYAAAAPAYSTYAAAAPA 786
           Y+AP        TY+A AP    TY+A APA           +  A AP      +    
Sbjct: 333 YSAPAPAPVVQQTYSAPAPAPQQTYSAPAPAVQEQTQVVQSYSAPAPAPVAQQTYSYPAP 392

Query: 787 YTASVYSAPAYTAPVTTYAAGAAYAAPV------TTYSAPAIVSP 825
                    A            +Y+AP        TYSAPA V  
Sbjct: 393 VVQQAPVVQAVAQ--QAPVVQQSYSAPAPAPVVQQTYSAPAPVVQ 435
 Score = 36.3 bits (83), Expect = 1.9
 Identities = 32/156 (20%), Positives = 50/156 (31%), Gaps = 7/156 (4%)

Query: 674 IDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPA- 732
             + ++ P    +  S  +P      + +Q     A   A  Q    A P+  Y+     
Sbjct: 591 APIQQSLPAPAPVVISAPAPAPAPAPVQLQQSFVPAP-PAPIQIQQPAQPIVQYSPPVVQ 649

Query: 733 --YAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTAS 790
                +  AP       A   A   A  + A  A A +  +     Y    +AA + +  
Sbjct: 650 QQVTYTQPAPAPIQVAAAAPVAKFFAILSLALLAVASADVSHLTNTYLPPKSAAASTSYE 709

Query: 791 VYSAPAYTAPVTTYAAGAAYAAPVT---TYSAPAIV 823
            Y A    A  +      A AA      +YSAPA  
Sbjct: 710 SYQAAPVEAAASETYVAPAAAASTYESESYSAPAAS 745
>gb|AAF49498.1| (AE003527) CG13043 gene product [Drosophila melanogaster]
          Length = 148

 Score =  103 bits (256), Expect = 1e-20
 Identities = 43/141 (30%), Positives = 65/141 (45%), Gaps = 6/141 (4%)

Query: 670 ALYEIDVTRNKPRYVS--LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTY 727
           AL  +   R      S  L Y+  + T       +  +  +   +  A +    S V ++
Sbjct: 9   ALLAVAAARPGHLLESSPLVYAAPAATTIVQEPVLAKVGAVVKSVPTAVSHQSQSVVHSH 68

Query: 728 AAAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPA 786
           A          APV  S PV +YAAAAP  +++YAAA   +++YAA AP   T  AAA  
Sbjct: 69  AHV---VEDVVAPVVKSTPVVSYAAAAPVVHTSYAAAPVVHTSYAAPAPVVHTSYAAAAP 125

Query: 787 YTASVYSAPAYTAPVTTYAAG 807
             A+ Y+  A ++P+T  A G
Sbjct: 126 VLATSYAQVAASSPLTYTATG 146
 Score =  103 bits (256), Expect = 1e-20
 Identities = 43/141 (30%), Positives = 65/141 (45%), Gaps = 6/141 (4%)

Query: 670 ALYEIDVTRNKPRYVS--LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTY 727
           AL  +   R      S  L Y+  + T       +  +  +   +  A +    S V ++
Sbjct: 9   ALLAVAAARPGHLLESSPLVYAAPAATTIVQEPVLAKVGAVVKSVPTAVSHQSQSVVHSH 68

Query: 728 AAAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPA 786
           A          APV  S PV +YAAAAP  +++YAAA   +++YAA AP   T  AAA  
Sbjct: 69  AHV---VEDVVAPVVKSTPVVSYAAAAPVVHTSYAAAPVVHTSYAAPAPVVHTSYAAAAP 125

Query: 787 YTASVYSAPAYTAPVTTYAAG 807
             A+ Y+  A ++P+T  A G
Sbjct: 126 VLATSYAQVAASSPLTYTATG 146
 Score = 45.6 bits (107), Expect = 0.003
 Identities = 30/123 (24%), Positives = 42/123 (33%), Gaps = 43/123 (34%)

Query: 705 L---------------------------------------ICLALCIAAAQAGFIASPVT 725
           L                                         +   +  A +    S V 
Sbjct: 7   LSALLAVAAARPGHLLESSPLVYAAPAATTIVQEPVLAKVGAVVKSVPTAVSHQSQSVVH 66

Query: 726 TYAAAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAA 784
           ++A          APV  S PV +YAAAAP  +++YAAA   +++YAA AP   T  AAA
Sbjct: 67  SHAHV---VEDVVAPVVKSTPVVSYAAAAPVVHTSYAAAPVVHTSYAAPAPVVHTSYAAA 123

Query: 785 PAY 787
              
Sbjct: 124 APV 126
>ref|XP_082817.1| (XM_082817) CG5095 [Drosophila melanogaster]
          Length = 409

 Score =  103 bits (255), Expect = 1e-20
 Identities = 43/149 (28%), Positives = 60/149 (39%), Gaps = 13/149 (8%)

Query: 685 SLAYSGCSPTKGYFLLFIQFLICLALCIA-AAQAGFIASPVTTYAAA---PAYAASYAAP 740
           + + +  +      + +      +       A +    +P  TY+A    PA   S  AP
Sbjct: 148 ASSSASANSYSAPSVSYSAPAPAVTYSAPAPAVSYSAPAPAVTYSAPAPAPAVTYSAPAP 207

Query: 741 V--AYSAPVATYAAAAP-AYSTYAAAAPAY---STYAAAAPAYSTYAAAAPAYTASVYSA 794
           V    +AP  TY+A AP    TY+A APA     +  A AP     AA A  Y+A   + 
Sbjct: 208 VVRVQAAPAVTYSAPAPAPAVTYSAPAPAPAVTYSAPAPAPVVRVQAAPAVTYSAPAPAV 267

Query: 795 PAYTAPVTTYAAGAAYAAPVTTYSAPAIV 823
              T      A   +  AP  TYSAPA V
Sbjct: 268 ---TYSAPAPAVTYSGPAPAVTYSAPAPV 293
 Score = 98.6 bits (243), Expect = 4e-19
 Identities = 41/155 (26%), Positives = 53/155 (33%), Gaps = 28/155 (18%)

Query: 672 YEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIA---AAQAGFIASPVTTYA 728
           Y            ++ YS  +P     + +      +         A      +PV    
Sbjct: 164 YSAPA-------PAVTYSAPAP----AVSYSAPAPAVTYSAPAPAPAVTYSAPAPVVRVQ 212

Query: 729 AAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYT 788
           AAPA   S  AP    AP  TY+A APA            +  A AP     AA A  Y+
Sbjct: 213 AAPAVTYSAPAP----APAVTYSAPAPA-------PAVTYSAPAPAPVVRVQAAPAVTYS 261

Query: 789 ASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIV 823
           A   +    T      A   +  AP  TYSAPA V
Sbjct: 262 APAPAV---TYSAPAPAVTYSGPAPAVTYSAPAPV 293
 Score = 90.8 bits (223), Expect = 8e-17
 Identities = 44/153 (28%), Positives = 56/153 (35%), Gaps = 33/153 (21%)

Query: 672 YEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAP 731
           Y            +++YS  +P     + +           A A      +PV    AAP
Sbjct: 173 YSAPA-------PAVSYSAPAP----AVTYSAPAP------APAVTYSAPAPVVRVQAAP 215

Query: 732 AYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTAS 790
           A   S  AP    AP  TY+A AP    TY+A         A AP     AA A  Y+A 
Sbjct: 216 AVTYSAPAP----APAVTYSAPAPAPAVTYSAP--------APAPVVRVQAAPAVTYSAP 263

Query: 791 VYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIV 823
             +    T      A   +  AP  TYSAPA V
Sbjct: 264 APAV---TYSAPAPAVTYSGPAPAVTYSAPAPV 293
 Score = 86.1 bits (211), Expect = 2e-15
 Identities = 41/140 (29%), Positives = 52/140 (36%), Gaps = 6/140 (4%)

Query: 688 YSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA-PAYAASYAAPVAYSAP 746
           YS  + +      +    +      A A      +P  +Y+A  PA   S  AP    AP
Sbjct: 144 YSSSASSSASANSYSAPSVSY-SAPAPAVTYSAPAPAVSYSAPAPAVTYSAPAP----AP 198

Query: 747 VATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAA 806
             TY+A AP     AA A  YS  A A     +  A APA T S  +           A 
Sbjct: 199 AVTYSAPAPVVRVQAAPAVTYSAPAPAPAVTYSAPAPAPAVTYSAPAPAPVVRVQAAPAV 258

Query: 807 GAAYAAPVTTYSAPAIVSPI 826
             +  AP  TYSAPA     
Sbjct: 259 TYSAPAPAVTYSAPAPAVTY 278
 Score = 74.8 bits (182), Expect = 5e-12
 Identities = 48/150 (32%), Positives = 60/150 (40%), Gaps = 14/150 (9%)

Query: 684 VSLAY---SGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA-PAYAASYAA 739
            S +Y   SG     G +              A + +    +P  TY+A  PA + S  A
Sbjct: 127 PSYSYGRSSGYGGNYGGYSSSASSSASANSYSAPSVSYSAPAPAVTYSAPAPAVSYSAPA 186

Query: 740 PVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYA-AAAPAYTASVYS-APA 796
           P        TY+A AP    TY+A AP     AA A  YS  A A A  Y+A   + A  
Sbjct: 187 PAV------TYSAPAPAPAVTYSAPAPVVRVQAAPAVTYSAPAPAPAVTYSAPAPAPAVT 240

Query: 797 YTAPVTTYAAGAAYAAPVTTYSAPAIVSPI 826
           Y+AP          AAP  TYSAPA     
Sbjct: 241 YSAPAPAP-VVRVQAAPAVTYSAPAPAVTY 269
 Score = 73.3 bits (178), Expect = 2e-11
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 10/109 (9%)

Query: 675 DVTRNKPRYV-SLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA-PA 732
            VT + P    ++ YS  +P              + +  A A      +P  TY+A  PA
Sbjct: 216 AVTYSAPAPAPAVTYSAPAPAPAVTYSAPAPAPVVRVQAAPAVTYSAPAPAVTYSAPAPA 275

Query: 733 YAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTY 780
              S  AP        TY+A AP     Y+A APA  +Y A AP     
Sbjct: 276 VTYSGPAPAV------TYSAPAPVPVVRYSAPAPAPISY-APAPVSYAP 317
>gb|AAL49309.1| (AY071687) RH10371p [Drosophila melanogaster]
          Length = 148

 Score =  102 bits (253), Expect = 3e-20
 Identities = 43/141 (30%), Positives = 65/141 (45%), Gaps = 6/141 (4%)

Query: 670 ALYEIDVTRNKPRYVS--LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTY 727
           AL  +   R      S  L Y+  + T       +  +  +   +  A +    S V ++
Sbjct: 9   ALLAVAAARPGHLLESSPLVYAAPAATTIVQEPVLAKVGAVVKSVRTAVSHQSQSVVHSH 68

Query: 728 AAAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPA 786
           A          APV  S PV +YAAAAP  +++YAAA   +++YAA AP   T  AAA  
Sbjct: 69  AHV---VEDVVAPVVKSTPVVSYAAAAPVVHTSYAAAPVVHTSYAAPAPVVHTSYAAAAP 125

Query: 787 YTASVYSAPAYTAPVTTYAAG 807
             A+ Y+  A ++P+T  A G
Sbjct: 126 VLATSYAQVAASSPLTYTATG 146
 Score =  102 bits (253), Expect = 3e-20
 Identities = 43/141 (30%), Positives = 65/141 (45%), Gaps = 6/141 (4%)

Query: 670 ALYEIDVTRNKPRYVS--LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTY 727
           AL  +   R      S  L Y+  + T       +  +  +   +  A +    S V ++
Sbjct: 9   ALLAVAAARPGHLLESSPLVYAAPAATTIVQEPVLAKVGAVVKSVRTAVSHQSQSVVHSH 68

Query: 728 AAAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPA 786
           A          APV  S PV +YAAAAP  +++YAAA   +++YAA AP   T  AAA  
Sbjct: 69  AHV---VEDVVAPVVKSTPVVSYAAAAPVVHTSYAAAPVVHTSYAAPAPVVHTSYAAAAP 125

Query: 787 YTASVYSAPAYTAPVTTYAAG 807
             A+ Y+  A ++P+T  A G
Sbjct: 126 VLATSYAQVAASSPLTYTATG 146
 Score = 44.1 bits (103), Expect = 0.010
 Identities = 30/123 (24%), Positives = 42/123 (33%), Gaps = 43/123 (34%)

Query: 705 L---------------------------------------ICLALCIAAAQAGFIASPVT 725
           L                                         +   +  A +    S V 
Sbjct: 7   LSALLAVAAARPGHLLESSPLVYAAPAATTIVQEPVLAKVGAVVKSVRTAVSHQSQSVVH 66

Query: 726 TYAAAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAA 784
           ++A          APV  S PV +YAAAAP  +++YAAA   +++YAA AP   T  AAA
Sbjct: 67  SHAHV---VEDVVAPVVKSTPVVSYAAAAPVVHTSYAAAPVVHTSYAAPAPVVHTSYAAA 123

Query: 785 PAY 787
              
Sbjct: 124 APV 126
>ref|XP_082690.1| (XM_082690) CG1368 [Drosophila melanogaster]
 gb|AAF48343.1| (AE003495) CG1368 gene product [Drosophila melanogaster]
          Length = 186

 Score = 97.0 bits (239), Expect = 1e-18
 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 4/116 (3%)

Query: 711 CIAAAQAGFIASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTY 770
            +   Q+   A+P  +Y+A  A   +YAAP    + VA      P   TY+A A   +  
Sbjct: 24  YLPPVQS-SYAAPSVSYSAP-AVQQTYAAPAIQQSYVAPSNEYLPPVQTYSAPAVQRT-- 79

Query: 771 AAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPI 826
            +A     TY+A + +Y+A   S  A +   +  A   +Y+AP  +YSAPA+    
Sbjct: 80  YSAPAVQRTYSAPSVSYSAPSVSYSAPSVSYSAPAVQQSYSAPSVSYSAPAVQQSY 135
 Score = 97.0 bits (239), Expect = 1e-18
 Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 4/116 (3%)

Query: 711 CIAAAQAGFIASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTY 770
            +   Q+   A+P  +Y+A  A   +YAAP    + VA      P   TY+A A   +  
Sbjct: 24  YLPPVQS-SYAAPSVSYSAP-AVQQTYAAPAIQQSYVAPSNEYLPPVQTYSAPAVQRT-- 79

Query: 771 AAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPI 826
            +A     TY+A + +Y+A   S  A +   +  A   +Y+AP  +YSAPA+    
Sbjct: 80  YSAPAVQRTYSAPSVSYSAPSVSYSAPSVSYSAPAVQQSYSAPSVSYSAPAVQQSY 135
 Score = 94.3 bits (232), Expect = 7e-18
 Identities = 37/133 (27%), Positives = 57/133 (42%), Gaps = 14/133 (10%)

Query: 705 LICLALCIAAAQAG-----------FIASPVTTYAAAPAYAASYAAPVAYSAPVATYAAA 753
              L  C+AA  +              A+P  +Y+A  A   +YAAP    + VA     
Sbjct: 6   AFALFACVAADVSHLSNEYLPPVQSSYAAPSVSYSAP-AVQQTYAAPAIQQSYVAPSNEY 64

Query: 754 APAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAP 813
            P   TY+A A   +   +A     TY+A + +Y+A   S  A +   +  A   +Y+AP
Sbjct: 65  LPPVQTYSAPAVQRT--YSAPAVQRTYSAPSVSYSAPSVSYSAPSVSYSAPAVQQSYSAP 122

Query: 814 VTTYSAPAIVSPI 826
             +YSAPA+    
Sbjct: 123 SVSYSAPAVQQSY 135
 Score = 92.0 bits (226), Expect = 4e-17
 Identities = 34/137 (24%), Positives = 53/137 (37%), Gaps = 12/137 (8%)

Query: 690 GCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPVAYSAPVAT 749
            C       L         +   A + +           +APA   +YAAP    + VA 
Sbjct: 11  ACVAADVSHLSNEYLPPVQSSYAAPSVSY----------SAPAVQQTYAAPAIQQSYVAP 60

Query: 750 YAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAA 809
                P   TY+A A   +   +A     TY+A + +Y+A   S  A +   +  A   +
Sbjct: 61  SNEYLPPVQTYSAPAVQRT--YSAPAVQRTYSAPSVSYSAPSVSYSAPSVSYSAPAVQQS 118

Query: 810 YAAPVTTYSAPAIVSPI 826
           Y+AP  +YSAPA+    
Sbjct: 119 YSAPSVSYSAPAVQQSY 135
 Score = 81.1 bits (198), Expect = 8e-14
 Identities = 33/144 (22%), Positives = 62/144 (42%), Gaps = 14/144 (9%)

Query: 684 VSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPVAY 743
            S++YS  +        +    I  +    + +      PV TY+A  A   +Y+AP   
Sbjct: 35  PSVSYSAPA----VQQTYAAPAIQQSYVAPSNEYLP---PVQTYSAP-AVQRTYSAPAVQ 86

Query: 744 SAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVY--SAPAYTAPV 801
               A   + +    +Y+A +    +Y+A A    +Y+A + +Y+A     S  A +   
Sbjct: 87  RTYSAPSVSYSAPSVSYSAPSV---SYSAPA-VQQSYSAPSVSYSAPAVQQSYSAPSVSY 142

Query: 802 TTYAAGAAYAAPVTTYSAPAIVSP 825
           +  A   +Y+AP  +YSAP++   
Sbjct: 143 SAPAVQQSYSAPAVSYSAPSVSYS 166
 Score = 81.1 bits (198), Expect = 8e-14
 Identities = 33/144 (22%), Positives = 62/144 (42%), Gaps = 14/144 (9%)

Query: 684 VSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPVAY 743
            S++YS  +        +    I  +    + +      PV TY+A  A   +Y+AP   
Sbjct: 35  PSVSYSAPA----VQQTYAAPAIQQSYVAPSNEYLP---PVQTYSAP-AVQRTYSAPAVQ 86

Query: 744 SAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVY--SAPAYTAPV 801
               A   + +    +Y+A +    +Y+A A    +Y+A + +Y+A     S  A +   
Sbjct: 87  RTYSAPSVSYSAPSVSYSAPSV---SYSAPA-VQQSYSAPSVSYSAPAVQQSYSAPSVSY 142

Query: 802 TTYAAGAAYAAPVTTYSAPAIVSP 825
           +  A   +Y+AP  +YSAP++   
Sbjct: 143 SAPAVQQSYSAPAVSYSAPSVSYS 166
 Score = 81.1 bits (198), Expect = 8e-14
 Identities = 33/144 (22%), Positives = 62/144 (42%), Gaps = 14/144 (9%)

Query: 684 VSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPVAY 743
            S++YS  +        +    I  +    + +      PV TY+A  A   +Y+AP   
Sbjct: 35  PSVSYSAPA----VQQTYAAPAIQQSYVAPSNEYLP---PVQTYSAP-AVQRTYSAPAVQ 86

Query: 744 SAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVY--SAPAYTAPV 801
               A   + +    +Y+A +    +Y+A A    +Y+A + +Y+A     S  A +   
Sbjct: 87  RTYSAPSVSYSAPSVSYSAPSV---SYSAPA-VQQSYSAPSVSYSAPAVQQSYSAPSVSY 142

Query: 802 TTYAAGAAYAAPVTTYSAPAIVSP 825
           +  A   +Y+AP  +YSAP++   
Sbjct: 143 SAPAVQQSYSAPAVSYSAPSVSYS 166
 Score = 69.0 bits (167), Expect = 3e-10
 Identities = 30/135 (22%), Positives = 51/135 (37%), Gaps = 12/135 (8%)

Query: 684 VSLAYSGCSPTKGYFLLFIQFLICLAL--CIAAAQAGFIASPVTTYAAAPAYAASYAAPV 741
            S++YS  +  + Y    IQ          +   Q     +   TY+A        A  V
Sbjct: 35  PSVSYSAPAVQQTYAAPAIQQSYVAPSNEYLPPVQTYSAPAVQRTYSAPAVQRTYSAPSV 94

Query: 742 AYSAPVATYAAAAPAYSTYAAAAP-----AYSTYAAAAPAYSTYAAAAPAYTASVY--SA 794
           +YSAP  +Y+A      +Y+A A      A S   +A     +Y+A + +Y+A     S 
Sbjct: 95  SYSAPSVSYSA---PSVSYSAPAVQQSYSAPSVSYSAPAVQQSYSAPSVSYSAPAVQQSY 151

Query: 795 PAYTAPVTTYAAGAA 809
            A     +  +   +
Sbjct: 152 SAPAVSYSAPSVSYS 166
 Score = 65.5 bits (158), Expect = 3e-09
 Identities = 31/147 (21%), Positives = 52/147 (35%), Gaps = 21/147 (14%)

Query: 672 YEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLAL--CIAAAQAGFIASPVTTYAA 729
           Y            S++YS  +  + Y    IQ          +   Q     +   TY+A
Sbjct: 32  YAAP---------SVSYSAPAVQQTYAAPAIQQSYVAPSNEYLPPVQTYSAPAVQRTYSA 82

Query: 730 APAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAP-----AYSTYAAAAPAYSTYAAAA 784
                   A  V+YSAP  +Y+A      +Y+A A      A S   +A     +Y+A +
Sbjct: 83  PAVQRTYSAPSVSYSAPSVSYSA---PSVSYSAPAVQQSYSAPSVSYSAPAVQQSYSAPS 139

Query: 785 PAYTASVY--SAPAYTAPVTTYAAGAA 809
            +Y+A     S  A     +  +   +
Sbjct: 140 VSYSAPAVQQSYSAPAVSYSAPSVSYS 166
 Score = 61.6 bits (148), Expect = 5e-08
 Identities = 31/133 (23%), Positives = 56/133 (41%), Gaps = 13/133 (9%)

Query: 679 NKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYA 738
           N+       YS  +        +    +       +      ++P  +Y+A     ++ A
Sbjct: 62  NEYLPPVQTYSAPA----VQRTYSAPAVQRTYSAPSVSY---SAPSVSYSAPSVSYSAPA 114

Query: 739 APVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYT 798
              +YSAP  +Y+A A    +Y+A +    +Y+A A    +Y+A A +Y+A   S  A +
Sbjct: 115 VQQSYSAPSVSYSAPA-VQQSYSAPSV---SYSAPA-VQQSYSAPAVSYSAPSVSYSAPS 169

Query: 799 APV-TTYAAGAAY 810
             V T YA+   Y
Sbjct: 170 VDVGTQYASNGGY 182
 Score = 55.4 bits (132), Expect = 4e-06
 Identities = 27/122 (22%), Positives = 48/122 (39%), Gaps = 5/122 (4%)

Query: 672 YEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAP 731
           Y   V       V   YS  +  + Y    + +        A + +    +   +Y+A  
Sbjct: 64  YLPPVQTYSAPAVQRTYSAPAVQRTYSAPSVSYSAPSVSYSAPSVSYSAPAVQQSYSAPS 123

Query: 732 AYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYS----TYAAAAPAYSTYAAAAPAY 787
              ++ A   +YSAP  +Y+A A    +Y+A A +YS    +Y+A +    T  A+   Y
Sbjct: 124 VSYSAPAVQQSYSAPSVSYSAPA-VQQSYSAPAVSYSAPSVSYSAPSVDVGTQYASNGGY 182

Query: 788 TA 789
             
Sbjct: 183 VY 184
 Score = 48.0 bits (113), Expect = 7e-04
 Identities = 15/95 (15%), Positives = 32/95 (32%), Gaps = 5/95 (5%)

Query: 672 YEIDVTRNKPRYVSLAYSGCS-PTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA 730
           Y     +      S++YS  S       + +           A + +    +   +Y+A 
Sbjct: 80  YSAPAVQRTYSAPSVSYSAPSVSYSAPSVSYSAPA-VQQSYSAPSVSYSAPAVQQSYSAP 138

Query: 731 PAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAP 765
                SY+AP    +  A   + +    +Y+A + 
Sbjct: 139 SV---SYSAPAVQQSYSAPAVSYSAPSVSYSAPSV 170
 Score = 48.0 bits (113), Expect = 7e-04
 Identities = 15/95 (15%), Positives = 32/95 (32%), Gaps = 5/95 (5%)

Query: 672 YEIDVTRNKPRYVSLAYSGCS-PTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAA 730
           Y     +      S++YS  S       + +           A + +    +   +Y+A 
Sbjct: 80  YSAPAVQRTYSAPSVSYSAPSVSYSAPSVSYSAPA-VQQSYSAPSVSYSAPAVQQSYSAP 138

Query: 731 PAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAP 765
                SY+AP    +  A   + +    +Y+A + 
Sbjct: 139 SV---SYSAPAVQQSYSAPAVSYSAPSVSYSAPSV 170
 Score = 41.7 bits (97), Expect = 0.049
 Identities = 22/69 (31%), Positives = 32/69 (45%), Gaps = 6/69 (8%)

Query: 762 AAAPAYSTYAAAAPAYSTYAAAAPAYTASV----YSAPAYTAPVTTYAAGAAYAAPVTTY 817
           AA  ++ +     P  S+YAA + +Y+A      Y+APA        +    Y  PV TY
Sbjct: 14  AADVSHLSNEYLPPVQSSYAAPSVSYSAPAVQQTYAAPAIQQSYVAPS--NEYLPPVQTY 71

Query: 818 SAPAIVSPI 826
           SAPA+    
Sbjct: 72  SAPAVQRTY 80
>gb|AAF46806.1| (AE003456) CG13504 gene product [Drosophila melanogaster]
          Length = 195

 Score = 94.3 bits (232), Expect = 7e-18
 Identities = 31/174 (17%), Positives = 51/174 (28%), Gaps = 18/174 (10%)

Query: 671 LYEIDVTRNKPR---YVSLAYSGC---------------SPTKGYFLLFIQFLICLALCI 712
           L  +           + +  YS                        + +      +    
Sbjct: 9   LLAVATAAPGLLDYGHSAPDYSYAHAAPAITYAAAAPVIKSYAAPAITYAAPAPVIKSYA 68

Query: 713 AAAQAGFIASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAA 772
           A A +   A+P  +YAA     +  A      A  AT  +   +  ++A          A
Sbjct: 69  APAISYAHAAPAISYAAPTVVKSYAAPVAVKVAAPATSYSHFSSVVSHATPIVKSYAAPA 128

Query: 773 AAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPI 826
            A A       + A  A  Y+  A            +YAAP  +Y+APA+V   
Sbjct: 129 IAYAAPAPVIKSYAAPAISYAHAAPAISYAAPTVVKSYAAPAISYAAPALVKSY 182
 Score = 94.3 bits (232), Expect = 7e-18
 Identities = 31/174 (17%), Positives = 51/174 (28%), Gaps = 18/174 (10%)

Query: 671 LYEIDVTRNKPR---YVSLAYSGC---------------SPTKGYFLLFIQFLICLALCI 712
           L  +           + +  YS                        + +      +    
Sbjct: 9   LLAVATAAPGLLDYGHSAPDYSYAHAAPAITYAAAAPVIKSYAAPAITYAAPAPVIKSYA 68

Query: 713 AAAQAGFIASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAA 772
           A A +   A+P  +YAA     +  A      A  AT  +   +  ++A          A
Sbjct: 69  APAISYAHAAPAISYAAPTVVKSYAAPVAVKVAAPATSYSHFSSVVSHATPIVKSYAAPA 128

Query: 773 AAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAIVSPI 826
            A A       + A  A  Y+  A            +YAAP  +Y+APA+V   
Sbjct: 129 IAYAAPAPVIKSYAAPAISYAHAAPAISYAAPTVVKSYAAPAISYAAPALVKSY 182
>gb|AAF49497.1| (AE003527) CG13063 gene product [Drosophila melanogaster]
          Length = 129

 Score = 85.4 bits (209), Expect = 4e-15
 Identities = 33/124 (26%), Positives = 50/124 (39%), Gaps = 7/124 (5%)

Query: 670 ALYEIDVTRNKPRYVS-LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYA 728
           AL  + V R    Y S L Y+  + T       +  +  +   I  + +       +   
Sbjct: 9   ALLAVAVARPGHLYESPLVYAAPAATTVVQERSLAKVGSVVSSIPTSVS---HQSQSVVH 65

Query: 729 AAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAY 787
           +         APV  S PV +YAAAAP  ++ YAAA   +++YAA      T  AAA   
Sbjct: 66  SHSHVVEDIVAPVVKSTPVVSYAAAAPVVHTAYAAAPVVHTSYAAP--VVHTSYAAASPV 123

Query: 788 TASV 791
             + 
Sbjct: 124 VYNS 127
 Score = 82.6 bits (202), Expect = 3e-14
 Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 7/121 (5%)

Query: 670 ALYEIDVTRNKPRYVS-LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYA 728
           AL  + V R    Y S L Y+  + T       +  +  +   I  + +       +   
Sbjct: 9   ALLAVAVARPGHLYESPLVYAAPAATTVVQERSLAKVGSVVSSIPTSVS---HQSQSVVH 65

Query: 729 AAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAY 787
           +         APV  S PV +YAAAAP  ++ YAAA   +++YAA      T  AAA   
Sbjct: 66  SHSHVVEDIVAPVVKSTPVVSYAAAAPVVHTAYAAAPVVHTSYAAP--VVHTSYAAASPV 123

Query: 788 T 788
            
Sbjct: 124 V 124
 Score = 75.6 bits (184), Expect = 3e-12
 Identities = 29/108 (26%), Positives = 45/108 (40%), Gaps = 5/108 (4%)

Query: 670 ALYEIDVTRNKPRYVS-LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYA 728
           AL  + V R    Y S L Y+  + T       +  +  +   I  + +       +   
Sbjct: 9   ALLAVAVARPGHLYESPLVYAAPAATTVVQERSLAKVGSVVSSIPTSVS---HQSQSVVH 65

Query: 729 AAPAYAASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAP 775
           +         APV  S PV +YAAAAP  ++ YAAA   +++YAA   
Sbjct: 66  SHSHVVEDIVAPVVKSTPVVSYAAAAPVVHTAYAAAPVVHTSYAAPVV 113
 Score = 42.9 bits (100), Expect = 0.023
 Identities = 32/125 (25%), Positives = 42/125 (33%), Gaps = 41/125 (32%)

Query: 702 IQFLICLALCIAAAQAGFIA--SPVTTYAAAPAYA------------------------- 734
           +  L+ L+  +A A A           YAA  A                           
Sbjct: 1   MFKLVVLSALLAVAVARPGHLYESPLVYAAPAATTVVQERSLAKVGSVVSSIPTSVSHQS 60

Query: 735 -----------ASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAA 782
                          APV  S PV +YAAAAP  ++ YAAA   +++YAA      T  A
Sbjct: 61  QSVVHSHSHVVEDIVAPVVKSTPVVSYAAAAPVVHTAYAAAPVVHTSYAAP--VVHTSYA 118

Query: 783 AAPAY 787
           AA   
Sbjct: 119 AASPV 123
 Score = 42.9 bits (100), Expect = 0.023
 Identities = 32/125 (25%), Positives = 42/125 (33%), Gaps = 41/125 (32%)

Query: 702 IQFLICLALCIAAAQAGFIA--SPVTTYAAAPAYA------------------------- 734
           +  L+ L+  +A A A           YAA  A                           
Sbjct: 1   MFKLVVLSALLAVAVARPGHLYESPLVYAAPAATTVVQERSLAKVGSVVSSIPTSVSHQS 60

Query: 735 -----------ASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYAA 782
                          APV  S PV +YAAAAP  ++ YAAA   +++YAA      T  A
Sbjct: 61  QSVVHSHSHVVEDIVAPVVKSTPVVSYAAAAPVVHTAYAAAPVVHTSYAAP--VVHTSYA 118

Query: 783 AAPAY 787
           AA   
Sbjct: 119 AASPV 123
 Score = 37.1 bits (85), Expect = 1.3
 Identities = 29/119 (24%), Positives = 39/119 (32%), Gaps = 41/119 (34%)

Query: 702 IQFLICLALCIAAAQAGFIA--SPVTTYAAAPAYA------------------------- 734
           +  L+ L+  +A A A           YAA  A                           
Sbjct: 1   MFKLVVLSALLAVAVARPGHLYESPLVYAAPAATTVVQERSLAKVGSVVSSIPTSVSHQS 60

Query: 735 -----------ASYAAPVAYSAPVATYAAAAP-AYSTYAAAAPAYSTYAAAAPAYSTYA 781
                          APV  S PV +YAAAAP  ++ YAAA   +++YAA      T  
Sbjct: 61  QSVVHSHSHVVEDIVAPVVKSTPVVSYAAAAPVVHTAYAAAPVVHTSYAAP--VVHTSY 117
>gb|AAF50552.1| (AE003559) CG8541 gene product [Drosophila melanogaster]
          Length = 275

 Score = 81.1 bits (198), Expect = 7e-14
 Identities = 40/159 (25%), Positives = 56/159 (35%), Gaps = 12/159 (7%)

Query: 677 TRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAAS 736
           T+  P          +P     +        LA       +           +APA   +
Sbjct: 92  TQATPIVSKTLVHAPAPVVEKTVYAAAPAPVLAK---TVYSAPAPVVAKHVYSAPAQVYA 148

Query: 737 YAAPVAYSA---PVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYST--YAAAAPAYTASV 791
            AAPV         A   AA        A   A + Y+A AP  +   Y+A AP Y AS 
Sbjct: 149 PAAPVVAKTVYSAPAPVYAAPAPVYAAPAPVVAKTVYSAPAPVLAKTVYSAPAPVYAASA 208

Query: 792 YSA---PAYTAPVTTYAAGAAYAAPVTTYSAPAI-VSPI 826
            +     +Y AP+ T       AA   T++APA+ VS  
Sbjct: 209 PAVAKTVSYAAPLATTNVNHGPAATTYTHNAPALGVSSY 247
 Score = 81.1 bits (198), Expect = 7e-14
 Identities = 40/159 (25%), Positives = 56/159 (35%), Gaps = 12/159 (7%)

Query: 677 TRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAAS 736
           T+  P          +P     +        LA       +           +APA   +
Sbjct: 92  TQATPIVSKTLVHAPAPVVEKTVYAAAPAPVLAK---TVYSAPAPVVAKHVYSAPAQVYA 148

Query: 737 YAAPVAYSA---PVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYST--YAAAAPAYTASV 791
            AAPV         A   AA        A   A + Y+A AP  +   Y+A AP Y AS 
Sbjct: 149 PAAPVVAKTVYSAPAPVYAAPAPVYAAPAPVVAKTVYSAPAPVLAKTVYSAPAPVYAASA 208

Query: 792 YSA---PAYTAPVTTYAAGAAYAAPVTTYSAPAI-VSPI 826
            +     +Y AP+ T       AA   T++APA+ VS  
Sbjct: 209 PAVAKTVSYAAPLATTNVNHGPAATTYTHNAPALGVSSY 247
 Score = 81.1 bits (198), Expect = 7e-14
 Identities = 40/159 (25%), Positives = 56/159 (35%), Gaps = 12/159 (7%)

Query: 677 TRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAAS 736
           T+  P          +P     +        LA       +           +APA   +
Sbjct: 92  TQATPIVSKTLVHAPAPVVEKTVYAAAPAPVLAK---TVYSAPAPVVAKHVYSAPAQVYA 148

Query: 737 YAAPVAYSA---PVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYST--YAAAAPAYTASV 791
            AAPV         A   AA        A   A + Y+A AP  +   Y+A AP Y AS 
Sbjct: 149 PAAPVVAKTVYSAPAPVYAAPAPVYAAPAPVVAKTVYSAPAPVLAKTVYSAPAPVYAASA 208

Query: 792 YSA---PAYTAPVTTYAAGAAYAAPVTTYSAPAI-VSPI 826
            +     +Y AP+ T       AA   T++APA+ VS  
Sbjct: 209 PAVAKTVSYAAPLATTNVNHGPAATTYTHNAPALGVSSY 247
 Score = 81.1 bits (198), Expect = 7e-14
 Identities = 40/159 (25%), Positives = 56/159 (35%), Gaps = 12/159 (7%)

Query: 677 TRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAAS 736
           T+  P          +P     +        LA       +           +APA   +
Sbjct: 92  TQATPIVSKTLVHAPAPVVEKTVYAAAPAPVLAK---TVYSAPAPVVAKHVYSAPAQVYA 148

Query: 737 YAAPVAYSA---PVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYST--YAAAAPAYTASV 791
            AAPV         A   AA        A   A + Y+A AP  +   Y+A AP Y AS 
Sbjct: 149 PAAPVVAKTVYSAPAPVYAAPAPVYAAPAPVVAKTVYSAPAPVLAKTVYSAPAPVYAASA 208

Query: 792 YSA---PAYTAPVTTYAAGAAYAAPVTTYSAPAI-VSPI 826
            +     +Y AP+ T       AA   T++APA+ VS  
Sbjct: 209 PAVAKTVSYAAPLATTNVNHGPAATTYTHNAPALGVSSY 247
 Score = 70.6 bits (171), Expect = 1e-10
 Identities = 41/171 (23%), Positives = 54/171 (30%), Gaps = 38/171 (22%)

Query: 694 TKGYFLLFIQFLICLALCIAAAQAGFIASPV-----TTYAAAPAY-----AASYAAPVAY 743
           T                         + +P      T YAAAPA        S  APV  
Sbjct: 77  TPAIKTTTYGAAPLYTQATPIVSKTLVHAPAPVVEKTVYAAAPAPVLAKTVYSAPAPVVA 136

Query: 744 S---APVATYAAAAPAYST-------------------YAAAAPAYSTYAAAAPAYST-- 779
               +  A   A A                          A   A + Y+A AP  +   
Sbjct: 137 KHVYSAPAQVYAPAAPVVAKTVYSAPAPVYAAPAPVYAAPAPVVAKTVYSAPAPVLAKTV 196

Query: 780 YAAAAPAYTASVYSA---PAYTAPVTTYAAGAAYAAPVTTYSAPAI-VSPI 826
           Y+A AP Y AS  +     +Y AP+ T       AA   T++APA+ VS  
Sbjct: 197 YSAPAPVYAASAPAVAKTVSYAAPLATTNVNHGPAATTYTHNAPALGVSSY 247
 Score = 64.7 bits (156), Expect = 6e-09
 Identities = 34/148 (22%), Positives = 45/148 (29%), Gaps = 23/148 (15%)

Query: 676 VTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAA 735
           V    P      Y+                  LA       +           +APA   
Sbjct: 103 VHAPAPVVEKTVYAA------------APAPVLAK---TVYSAPAPVVAKHVYSAPAQVY 147

Query: 736 SYAAPVAYSA---PVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYST--YAAAAPAYTAS 790
           + AAPV         A   AA        A   A + Y+A AP  +   Y+A AP Y AS
Sbjct: 148 APAAPVVAKTVYSAPAPVYAAPAPVYAAPAPVVAKTVYSAPAPVLAKTVYSAPAPVYAAS 207

Query: 791 VYSA---PAYTAPVTTYAAGAAYAAPVT 815
             +     +Y AP+ T       AA   
Sbjct: 208 APAVAKTVSYAAPLATTNVNHGPAATTY 235
 Score = 61.2 bits (147), Expect = 7e-08
 Identities = 33/147 (22%), Positives = 44/147 (29%), Gaps = 36/147 (24%)

Query: 677 TRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAAS 736
               P      YS  +P     +                             +APA   +
Sbjct: 117 AAPAPVLAKTVYSAPAPVVAKHVY----------------------------SAPAQVYA 148

Query: 737 YAAPVAYSA---PVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYST--YAAAAPAYTASV 791
            AAPV         A   AA        A   A + Y+A AP  +   Y+A AP Y AS 
Sbjct: 149 PAAPVVAKTVYSAPAPVYAAPAPVYAAPAPVVAKTVYSAPAPVLAKTVYSAPAPVYAASA 208

Query: 792 YSA---PAYTAPVTTYAAGAAYAAPVT 815
            +     +Y AP+ T       AA   
Sbjct: 209 PAVAKTVSYAAPLATTNVNHGPAATTY 235
 Score = 43.3 bits (101), Expect = 0.016
 Identities = 29/144 (20%), Positives = 42/144 (29%), Gaps = 13/144 (9%)

Query: 685 SLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPV--- 741
           +L     +      +      +              A  V++Y+ A     S        
Sbjct: 11  ALVACANAGLLASHVAIANPSVDAVASTQQNVVRSFAGTVSSYSKAVDTPYSSVRKSDTR 70

Query: 742 ----AYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYA---AAAPAYTASVYSA 794
                Y+  + T    A    T A    + +   A AP         A AP    +VYSA
Sbjct: 71  IQNNVYTPAIKTTTYGAAPLYTQATPIVSKTLVHAPAPVVEKTVYAAAPAPVLAKTVYSA 130

Query: 795 PAYTAP---VTTYAAGAAYAAPVT 815
           PA        +  A   A AAPV 
Sbjct: 131 PAPVVAKHVYSAPAQVYAPAAPVV 154
 Score = 43.3 bits (101), Expect = 0.016
 Identities = 29/144 (20%), Positives = 42/144 (29%), Gaps = 13/144 (9%)

Query: 685 SLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPV--- 741
           +L     +      +      +              A  V++Y+ A     S        
Sbjct: 11  ALVACANAGLLASHVAIANPSVDAVASTQQNVVRSFAGTVSSYSKAVDTPYSSVRKSDTR 70

Query: 742 ----AYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYA---AAAPAYTASVYSA 794
                Y+  + T    A    T A    + +   A AP         A AP    +VYSA
Sbjct: 71  IQNNVYTPAIKTTTYGAAPLYTQATPIVSKTLVHAPAPVVEKTVYAAAPAPVLAKTVYSA 130

Query: 795 PAYTAP---VTTYAAGAAYAAPVT 815
           PA        +  A   A AAPV 
Sbjct: 131 PAPVVAKHVYSAPAQVYAPAAPVV 154
>gb|AAF46963.1| (AE003459) CG13545 gene product [Drosophila melanogaster]
          Length = 114

 Score = 74.1 bits (180), Expect = 9e-12
 Identities = 53/119 (44%), Positives = 66/119 (54%), Gaps = 11/119 (9%)

Query: 686 LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPVAYSA 745
           +  SG S         +QFL+CLAL IAAAQA  +A  V TY+A PA   + AAP     
Sbjct: 1   MKVSGVSFGPINPYYHLQFLVCLALFIAAAQAHVVAPAVATYSAVPALTYAAAAP----- 55

Query: 746 PVATYAAAAP-AYSTYAAAAP--AYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPV 801
            V TY+AA P AYS YAA +   A S YAA +   S+Y AA   Y  S Y+APA  + +
Sbjct: 56  -VTTYSAAIPRAYSAYAAPSVYAAPSVYAAPSVYSSSYVAAPSVY--SAYAAPAVVSTL 111
 Score = 74.1 bits (180), Expect = 9e-12
 Identities = 53/119 (44%), Positives = 66/119 (54%), Gaps = 11/119 (9%)

Query: 686 LAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPVAYSA 745
           +  SG S         +QFL+CLAL IAAAQA  +A  V TY+A PA   + AAP     
Sbjct: 1   MKVSGVSFGPINPYYHLQFLVCLALFIAAAQAHVVAPAVATYSAVPALTYAAAAP----- 55

Query: 746 PVATYAAAAP-AYSTYAAAAP--AYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPV 801
            V TY+AA P AYS YAA +   A S YAA +   S+Y AA   Y  S Y+APA  + +
Sbjct: 56  -VTTYSAAIPRAYSAYAAPSVYAAPSVYAAPSVYSSSYVAAPSVY--SAYAAPAVVSTL 111
 Score = 39.4 bits (91), Expect = 0.24
 Identities = 26/100 (26%), Positives = 35/100 (35%), Gaps = 12/100 (12%)

Query: 669 LALYEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYA 728
           LAL+      +        YS         L +           A  +A    +  + YA
Sbjct: 23  LALFIAAAQAHVVAPAVATYSA-----VPALTYAAAAPVTTYSAAIPRAYSAYAAPSVYA 77

Query: 729 AAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYS 768
           A       YAAP  YS+   +Y AA   YS YAA A   +
Sbjct: 78  APSV----YAAPSVYSS---SYVAAPSVYSAYAAPAVVST 110
 Score = 34.7 bits (79), Expect = 6.2
 Identities = 23/95 (24%), Positives = 32/95 (33%), Gaps = 20/95 (21%)

Query: 674 IDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAY 733
                      +L Y+  +P                   A  +A    +  + YAA    
Sbjct: 36  APAVATYSAVPALTYAAAAPVT-------------TYSAAIPRAYSAYAAPSVYAAPSV- 81

Query: 734 AASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYS 768
              YAAP  YS+   +Y AA   YS YAA A   +
Sbjct: 82  ---YAAPSVYSS---SYVAAPSVYSAYAAPAVVST 110
>gb|AAF48347.1| (AE003495) CG11585 gene product [Drosophila melanogaster]
          Length = 273

 Score = 69.4 bits (168), Expect = 2e-10
 Identities = 40/171 (23%), Positives = 72/171 (41%), Gaps = 28/171 (16%)

Query: 672 YEIDVTRNKPRYVSLAYSGCS--PTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAA 729
           Y          +VS +    +        +         +     + +  +A+P   Y A
Sbjct: 25  YSAPAASASASHVSYSAPAAAHSSYAAPSVSH----GSYSSASRTSYSAPVAAPSRKYLA 80

Query: 730 APAYA-ASYAAPVA----YSAPVATY-------------AAAAPAYSTYAAAAPAYSTYA 771
             A + +SY+APV     YSAP  ++             +A   +YS+Y+A A ++++Y+
Sbjct: 81  PAAVSHSSYSAPVVSRKSYSAPAVSHGSYSSSGGSSGSYSAPVASYSSYSAPAASHTSYS 140

Query: 772 AAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAI 822
           A   A S    A  A + S  +  +Y+AP  +  +    A  V++YSAPA+
Sbjct: 141 APVAAPSRQYLAPAASSYSAPAVSSYSAPAVSSYS----APAVSSYSAPAV 187
 Score = 69.4 bits (168), Expect = 2e-10
 Identities = 40/171 (23%), Positives = 72/171 (41%), Gaps = 28/171 (16%)

Query: 672 YEIDVTRNKPRYVSLAYSGCS--PTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAA 729
           Y          +VS +    +        +         +     + +  +A+P   Y A
Sbjct: 25  YSAPAASASASHVSYSAPAAAHSSYAAPSVSH----GSYSSASRTSYSAPVAAPSRKYLA 80

Query: 730 APAYA-ASYAAPVA----YSAPVATY-------------AAAAPAYSTYAAAAPAYSTYA 771
             A + +SY+APV     YSAP  ++             +A   +YS+Y+A A ++++Y+
Sbjct: 81  PAAVSHSSYSAPVVSRKSYSAPAVSHGSYSSSGGSSGSYSAPVASYSSYSAPAASHTSYS 140

Query: 772 AAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAPVTTYSAPAI 822
           A   A S    A  A + S  +  +Y+AP  +  +    A  V++YSAPA+
Sbjct: 141 APVAAPSRQYLAPAASSYSAPAVSSYSAPAVSSYS----APAVSSYSAPAV 187
 Score = 67.1 bits (162), Expect = 1e-09
 Identities = 42/190 (22%), Positives = 72/190 (37%), Gaps = 52/190 (27%)

Query: 681 PRYVSLAYSGCSPTKGYFLLF-----------------IQFLICLALCIAAAQAG----- 718
           P   +   SG S      +                          +   A + +      
Sbjct: 2   PAGPTPYSSGGSSYAAPSVSHVSYSAPAASASASHVSYSAPAAAHSSYAAPSVSHGSYSS 61

Query: 719 --------FIASPVTTYAAAPAYA-ASYAAPVA----YSAPVATY-------------AA 752
                    +A+P   Y A  A + +SY+APV     YSAP  ++             +A
Sbjct: 62  ASRTSYSAPVAAPSRKYLAPAAVSHSSYSAPVVSRKSYSAPAVSHGSYSSSGGSSGSYSA 121

Query: 753 AAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAA 812
              +YS+Y+A A ++++Y+A   A S    A  A + S  +  +Y+AP  +  +    A 
Sbjct: 122 PVASYSSYSAPAASHTSYSAPVAAPSRQYLAPAASSYSAPAVSSYSAPAVSSYS----AP 177

Query: 813 PVTTYSAPAI 822
            V++YSAPA+
Sbjct: 178 AVSSYSAPAV 187
 Score = 63.9 bits (154), Expect = 1e-08
 Identities = 35/151 (23%), Positives = 65/151 (42%), Gaps = 30/151 (19%)

Query: 672 YEIDVTRNKPRYVSLAYSGCSPTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAP 731
           Y   V     +Y+       +P       +   ++      A A +              
Sbjct: 67  YSAPVAAPSRKYL-------APAAVSHSSYSAPVVSRKSYSAPAVSHG------------ 107

Query: 732 AYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASV 791
           +Y++S  +  +YSAPVA+Y+       +Y+A A ++++Y+A   A S    A  A + S 
Sbjct: 108 SYSSSGGSSGSYSAPVASYS-------SYSAPAASHTSYSAPVAAPSRQYLAPAASSYSA 160

Query: 792 YSAPAYTAPVTTYAAGAAYAAPVTTYSAPAI 822
            +  +Y+AP  +  +    A  V++YSAPA+
Sbjct: 161 PAVSSYSAPAVSSYS----APAVSSYSAPAV 187
 Score = 63.2 bits (152), Expect = 2e-08
 Identities = 40/189 (21%), Positives = 71/189 (37%), Gaps = 59/189 (31%)

Query: 689 SGCSPTKGYFLLFIQFLICLALCIA----------------------------------- 713
           +G +P       +    +      A                                   
Sbjct: 3   AGPTPYSSGGSSYAAPSVSHVSYSAPAASASASHVSYSAPAAAHSSYAAPSVSHGSYSSA 62

Query: 714 --AAQAGFIASPVTTYAAAPAYA-ASYAAPVA----YSAPVATY-------------AAA 753
              + +  +A+P   Y A  A + +SY+APV     YSAP  ++             +A 
Sbjct: 63  SRTSYSAPVAAPSRKYLAPAAVSHSSYSAPVVSRKSYSAPAVSHGSYSSSGGSSGSYSAP 122

Query: 754 APAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTYAAGAAYAAP 813
             +YS+Y+A A ++++Y+A   A S    A  A + S  +  +Y+AP  +  +    A  
Sbjct: 123 VASYSSYSAPAASHTSYSAPVAAPSRQYLAPAASSYSAPAVSSYSAPAVSSYS----APA 178

Query: 814 VTTYSAPAI 822
           V++YSAPA+
Sbjct: 179 VSSYSAPAV 187
 Score = 53.8 bits (128), Expect = 1e-05
 Identities = 33/171 (19%), Positives = 60/171 (34%), Gaps = 55/171 (32%)

Query: 689 SGCSPTKGYFLLFIQFLICLALCIA----------------------------------- 713
           +G +P       +    +      A                                   
Sbjct: 3   AGPTPYSSGGSSYAAPSVSHVSYSAPAASASASHVSYSAPAAAHSSYAAPSVSHGSYSSA 62

Query: 714 --AAQAGFIASPVTTYAAAPAYA-ASYAAPVA----YSAPVATY-------------AAA 753
              + +  +A+P   Y A  A + +SY+APV     YSAP  ++             +A 
Sbjct: 63  SRTSYSAPVAAPSRKYLAPAAVSHSSYSAPVVSRKSYSAPAVSHGSYSSSGGSSGSYSAP 122

Query: 754 APAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAPVTTY 804
             +YS+Y+A A ++++Y+A   A S    A  A + S  +  +Y+AP  + 
Sbjct: 123 VASYSSYSAPAASHTSYSAPVAAPSRQYLAPAASSYSAPAVSSYSAPAVSS 173
>gb|AAB34025.1| Tm-E1a=cuticular protein [Tenebrio molitor=yellow meal worms,
           pharate larval and pupal abdominal cuticle, Peptide, 243
           aa]
          Length = 243

 Score = 42.1 bits (98), Expect = 0.033
 Identities = 41/169 (24%), Positives = 58/169 (34%), Gaps = 19/169 (11%)

Query: 672 YEIDVTRNKPRYVSLAYSGCS---PTKGYFLLFIQFLICLALCIAAAQAGFIASPVTTYA 728
           Y            +++Y+  +                +  A  +A + +    +      
Sbjct: 11  YAAAPAIASYAAPAVSYAAPAVSYAAPAVSYAAPAVAVAKAAPVATSYSYTAQATPAVSY 70

Query: 729 AAPAYAASYAAPVAYSAPVATYAAAAPAYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYT 788
           AAPA AA   A    +  VA+   AAPA   YAA A A   YAA A  Y+  A A+  Y 
Sbjct: 71  AAPAVAAVAPAVRYAAPAVASVGYAAPAVR-YAAPAVASVGYAAPALRYAAPAVASVGYA 129

Query: 789 ASVYSAPAYTAPVTTYAA---------------GAAYAAPVTTYSAPAI 822
           A      A    V + A                G A+AAP   Y+  A 
Sbjct: 130 APAVRYAAPAVRVASPAVSVHPAPAVRVAAPAIGYAHAAPAIGYAHAAP 178
 Score = 39.4 bits (91), Expect = 0.24
 Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 13/137 (9%)

Query: 697 YFLLFIQFLICLALCIAAAQAGFIASPVTTYAAAPAYAASYAAPVAYSAPVATYAAAAP- 755
             +        +A   A A +   A+P  +YAA     A+ A  VA +APVAT  +    
Sbjct: 6   PAISSYAAAPAIASYAAPAVSY--AAPAVSYAAPAVSYAAPAVAVAKAAPVATSYSYTAQ 63

Query: 756 ------AYSTYAAAAPAYSTYAAAAPAYSTYAAAAPAYTASVYSAPAYTAP---VTTYAA 806
                   +   AA      YAA A A   YAA A  Y A   ++  Y AP       A 
Sbjct: 64  ATPAVSYAAPAVAAVAPAVRYAAPAVASVGYAAPAVRYAAPAVASVGYAAPALRYAAPAV 123

Query: 807 GA-AYAAPVTTYSAPAI 822
            +  YAAP   Y+APA+
Sbjct: 124 ASVGYAAPAVRYAAPAV 140
CPU time:   331.81 user secs.	    3.48 sys. secs	  335.29 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.314    0.154    0.429 

Gapped
Lambda     K      H
   0.270   0.0539    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 461786246
Number of Sequences: 887402
Number of extensions: 22266027
Number of successful extensions: 473053
Number of sequences better than 10.0: 7602
Number of HSP's better than 10.0 without gapping: 3073
Number of HSP's successfully gapped in prelim test: 4923
Number of HSP's that attempted gapping in prelim test: 212673
Number of HSP's gapped (non-prelim): 72268
length of query: 830
length of database: 277,845,442
effective HSP length: 54
effective length of query: 776
effective length of database: 229,925,734
effective search space: 178422369584
effective search space used: 178422369584
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 77 (34.2 bits)