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GPI Anchor Biosynthesis Report: AAF46367.1 (PIG-T family, Drosophila melanogaster)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (633 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 2

Distribution of 17 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

ref|NP_572475.1| (NM_132247) CG11190 gene product [Drosophila me... 960 0.0
dbj|BAB60854.1| (AB057724) phosphatidyl inositol glycan class T ... 901 0.0
emb|CAC34729.1| (AJ308886) neuronal development-associated prote... 894 0.0
ref|XP_029858.3| (XM_029858) CGI-06 protein [Homo sapiens] >gi|6... 892 0.0
ref|NP_057021.1| (NM_015937) CGI-06 protein [Homo sapiens] >gi|4... 889 0.0
ref|NP_566299.1| (NM_111594) expressed protein [Arabidopsis thal... 702 0.0
gb|AAF20232.1|AC012395_19 (AC012395) unknown protein [Arabidopsi... 697 0.0
ref|NP_012058.1| (NC_001140) Glycosyl Phosphatidyl Inositol 16; ... 547 e-154
sp|P38875|YHY8_YEAST HYPOTHETICAL 67.8 KDA PROTEIN IN IKI1-ERG9 ... 547 e-154
ref|NP_505797.1| (NM_073396) F17C11.7.p [Caenorhabditis elegans]... 329 1e-88
pir||T39499 conserved hypothetical protein SPBC1604.15 - fission... 310 5e-83
emb|CAC36338.1| (AL021578) dJ453C12.7.3 (CGI-06 protein (LOC5160... 303 4e-81
emb|CAC36339.1| (AL021578) dJ453C12.7.2 (CGI-06 protein (LOC5160... 97 6e-19
Alignments
>ref|NP_572475.1| (NM_132247) CG11190 gene product [Drosophila melanogaster]
 gb|AAF46367.1| (AE003443) CG11190 gene product [Drosophila melanogaster]
 gb|AAL49059.1| (AY071437) RE52151p [Drosophila melanogaster]
          Length = 633

 Score =  960 bits (2457), Expect = 0.0
 Identities = 633/633 (100%), Positives = 633/633 (100%)

Query: 1   MYPVAFVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYGEKDNLY 60
           MYPVAFVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYGEKDNLY
Sbjct: 1   MYPVAFVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYGEKDNLY 60

Query: 61  HTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYPIVEATSGAEMWAWFSGANLTNR 120
           HTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYPIVEATSGAEMWAWFSGANLTNR
Sbjct: 61  HTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYPIVEATSGAEMWAWFSGANLTNR 120

Query: 121 DVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQRFVRYATLPREIVC 180
           DVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQRFVRYATLPREIVC
Sbjct: 121 DVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQRFVRYATLPREIVC 180

Query: 181 TENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTA 240
           TENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTA
Sbjct: 181 TENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTA 240

Query: 241 NLVYDLRLFELSNNDFSLRRLFGMGLNGYCELAESSKIYVQRNELGERYQLVPEPVHEVK 300
           NLVYDLRLFELSNNDFSLRRLFGMGLNGYCELAESSKIYVQRNELGERYQLVPEPVHEVK
Sbjct: 241 NLVYDLRLFELSNNDFSLRRLFGMGLNGYCELAESSKIYVQRNELGERYQLVPEPVHEVK 300

Query: 301 TTRGGHSVVYSVYDMHEQFKEAGERLFNVAWLAPKSANRRRNLAKPSLPPVTVHRYLLGH 360
           TTRGGHSVVYSVYDMHEQFKEAGERLFNVAWLAPKSANRRRNLAKPSLPPVTVHRYLLGH
Sbjct: 301 TTRGGHSVVYSVYDMHEQFKEAGERLFNVAWLAPKSANRRRNLAKPSLPPVTVHRYLLGH 360

Query: 361 GQERGRIVTEVTNSHYDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFKLL 420
           GQERGRIVTEVTNSHYDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFKLL
Sbjct: 361 GQERGRIVTEVTNSHYDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFKLL 420

Query: 421 HYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQ 480
           HYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQ
Sbjct: 421 HYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQ 480

Query: 481 LPMGRNYTALPPEGHLFEHSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVV 540
           LPMGRNYTALPPEGHLFEHSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVV
Sbjct: 481 LPMGRNYTALPPEGHLFEHSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVV 540

Query: 541 ALAFGPIHSVATKMIIVGRQTSAPKNFVKKIFNQLFRRGKATDETAAEGEGLPAAGAAAT 600
           ALAFGPIHSVATKMIIVGRQTSAPKNFVKKIFNQLFRRGKATDETAAEGEGLPAAGAAAT
Sbjct: 541 ALAFGPIHSVATKMIIVGRQTSAPKNFVKKIFNQLFRRGKATDETAAEGEGLPAAGAAAT 600

Query: 601 GVASGRAAISPGSPSGDQPLLEDLDEEEEEEQD 633
           GVASGRAAISPGSPSGDQPLLEDLDEEEEEEQD
Sbjct: 601 GVASGRAAISPGSPSGDQPLLEDLDEEEEEEQD 633
>dbj|BAB60854.1| (AB057724) phosphatidyl inositol glycan class T [Homo sapiens]
 gb|AAH15022.1|AAH15022 (BC015022) Unknown (protein for MGC:8909) [Homo sapiens]
          Length = 578

 Score =  901 bits (2305), Expect = 0.0
 Identities = 215/588 (36%), Positives = 324/588 (54%), Gaps = 30/588 (5%)

Query: 3   PVAFVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYG-EKDNLYH 61
           P+A ++LLL+ P          +   EELV+ PL    V   FQF TRW    +++ + H
Sbjct: 6   PLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQREGVSH 65

Query: 62  TQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYPIVEATSGAEMWAWFSGANLTNRD 121
            +L P+ + +L+ +++++ELH+  TQG WR   WG P ++A SGAE+W WF     T  D
Sbjct: 66  YRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQD---TVTD 122

Query: 122 VDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQR-FVRYATLPREIVC 180
           VD+ WKEL+NV SG+ CASLNF+D+TN++ P    +P  +  +    F+RYA LPRE+VC
Sbjct: 123 VDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREVVC 182

Query: 181 TENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTA 240
           TENLTPWKKLLPC S +G + LL +  + +T YHS  + +R +C +    +   EL QT 
Sbjct: 183 TENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQTL 242

Query: 241 NLVYDLRLFELSNNDFSLRRLFGMGLNGYCELAESSKIYVQ---RNELGERYQLVPEPVH 297
           ++V+D  +      D+SL R+F   L   C LA  S++YV     N+  E  ++ P P  
Sbjct: 243 SVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPPTT 302

Query: 298 EVKTTRGGHSVVYSVYDMHEQFKEAGERLFNV--AWLAPKSANRRRNLAKPSLPPVTVHR 355
             +    G    Y++YD+ +       R  N+   W  P           P +P +   R
Sbjct: 303 TYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPPENE------APPVPFLHAQR 356

Query: 356 YLLGHGQERGRIVTEVTNSH-YDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQR 414
           Y+ G+G ++G + T + N+H Y A P++L + +PWY+  Y+HTL+I  K        G+ 
Sbjct: 357 YVSGYGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSK--------GKE 408

Query: 415 LTFKLLHYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGS 474
                +HY P + R  P  LE+   LP  +   +SI  +  LLKW EY PD NHG Y+  
Sbjct: 409 NKPSYIHYQPAQDRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSP 468

Query: 475 AIVSSQLPMGRNYTALPP-EGHLFEHSFNATRPS-YVLSLHTEALIVSLPTPDFSMPYNV 532
           +++S+ +P       +   E  LF   F  +  S Y + L+TE L+V+LPTPDFSMPYNV
Sbjct: 469 SVLSALVPSMVAAKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNV 528

Query: 533 ICLACTVVALAFGPIHSVATKMIIVGRQTSAPKNFVKKIFNQLFRRGK 580
           ICL CTVVA+ +G  +++ T+   +    +      K++ N L RR +
Sbjct: 529 ICLTCTVVAVCYGSFYNLLTRTFHIEEPRTG--GLAKRLAN-LIRRAR 573
>emb|CAC34729.1| (AJ308886) neuronal development-associated protein [Mus musculus]
 dbj|BAB39711.1| (AB057593) Neuronal development-associated protein [Mus musculus]
 gb|AAK32809.1|AF361435_1 (AF361435) neuronal development-associated protein 7 [Mus musculus]
          Length = 578

 Score =  894 bits (2286), Expect = 0.0
 Identities = 216/588 (36%), Positives = 322/588 (54%), Gaps = 30/588 (5%)

Query: 3   PVAFVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYG-EKDNLYH 61
           P+  ++LLLV            +   EELV+ PL    V   FQF TRW    +++ + H
Sbjct: 6   PLRLLVLLLVGRGCCGCAEGPRDSLREELVITPLPSGDVAATFQFRTRWDSDLQREGVSH 65

Query: 62  TQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYPIVEATSGAEMWAWFSGANLTNRD 121
            +L P+ + +L+ +++++ELH+  TQG WR   WG P ++A SGAE+W WF     T  D
Sbjct: 66  YRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQD---TVTD 122

Query: 122 VDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQR-FVRYATLPREIVC 180
           VD+ W+EL+NV SG+ CASLNF+D TN++ P    +P  +  +    F+RYA LPRE+VC
Sbjct: 123 VDKSWRELSNVLSGIFCASLNFIDATNTVTPTASFKPLGLANDTDDYFLRYAVLPREVVC 182

Query: 181 TENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTA 240
           TENLTPWKKLLPC S +G + LL +  + +T YHS  + +R +C +    +   EL QT 
Sbjct: 183 TENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPICRNAHCTSISWELRQTL 242

Query: 241 NLVYDLRLFELSNNDFSLRRLFGMGLNGYCELAESSKIYVQ---RNELGERYQLVPEPVH 297
           ++V+D  +      D+SL R+F   L   C LA  S +YV     ++  E  ++ P P  
Sbjct: 243 SVVFDAFITGQGKKDWSLFRMFSRTLTEACPLASQSLVYVDITGYSQDNETLEVSPPPTS 302

Query: 298 EVKTTRGGHSVVYSVYDMHEQFKEAGERLFNV--AWLAPKSANRRRNLAKPSLPPVTVHR 355
             +    G    Y+VYD+ +       R  N+   W  P             +P +   R
Sbjct: 303 TYQDVILGTRKTYAVYDLFDTAMINNSRNLNIQLKWKRPPDNE------ALPVPFLHAQR 356

Query: 356 YLLGHGQERGRIVTEVTNSH-YDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQR 414
           Y+ G+G ++G + T + NSH Y A P++L +V+PWY+  Y+HTL+I  K        G+ 
Sbjct: 357 YVSGYGLQKGELSTLLYNSHPYRAFPVLLLDVVPWYLRLYVHTLTITSK--------GKE 408

Query: 415 LTFKLLHYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGS 474
                +HY P + R+ P  LE+   LP  +   +SI  +  LLKW EY PD NHG Y+  
Sbjct: 409 NKPSYIHYQPAQDRQQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSP 468

Query: 475 AIVSSQLPMGRNYTALPPEG-HLFEHSFNATR-PSYVLSLHTEALIVSLPTPDFSMPYNV 532
           +++S+ +P       +  EG  LF   F  +   SY + L+TE L+V+LPTPDFSMPYNV
Sbjct: 469 SVLSALVPSVVAAKPVDWEGSPLFNTLFPVSDGSSYFVRLYTEPLLVNLPTPDFSMPYNV 528

Query: 533 ICLACTVVALAFGPIHSVATKMIIVGRQTSAPKNFVKKIFNQLFRRGK 580
           ICL CTVVA+ +G  +++ T+   +    S      K++ N L RR +
Sbjct: 529 ICLTCTVVAVCYGSFYNLLTRTFHIEEPKSG--GLAKRLAN-LIRRAR 573
>ref|XP_029858.3| (XM_029858) CGI-06 protein [Homo sapiens]
 emb|CAB57341.1| (AL121742) hypothetical protein [Homo sapiens]
 emb|CAC18110.1| (AL021578) dJ453C12.7.1 (CGI-06 protein (LOC51604), isoform 1)
           [Homo sapiens]
          Length = 574

 Score =  892 bits (2282), Expect = 0.0
 Identities = 215/588 (36%), Positives = 324/588 (54%), Gaps = 30/588 (5%)

Query: 3   PVAFVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYG-EKDNLYH 61
           P+A ++LLL+ P          +   EELV+ PL    V   FQF TRW    +++ + H
Sbjct: 2   PLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQREGVSH 61

Query: 62  TQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYPIVEATSGAEMWAWFSGANLTNRD 121
            +L P+ + +L+ +++++ELH+  TQG WR   WG P ++A SGAE+W WF     T  D
Sbjct: 62  YRLFPKALGQLISKYSLRELHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQD---TVTD 118

Query: 122 VDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQR-FVRYATLPREIVC 180
           VD+ WKEL+NV SG+ CASLNF+D+TN++ P    +P  +  +    F+RYA LPRE+VC
Sbjct: 119 VDKSWKELSNVLSGIFCASLNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREVVC 178

Query: 181 TENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTA 240
           TENLTPWKKLLPC S +G + LL +  + +T YHS  + +R +C +    +   EL QT 
Sbjct: 179 TENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQTL 238

Query: 241 NLVYDLRLFELSNNDFSLRRLFGMGLNGYCELAESSKIYVQ---RNELGERYQLVPEPVH 297
           ++V+D  +      D+SL R+F   L   C LA  S++YV     N+  E  ++ P P  
Sbjct: 239 SVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPPTT 298

Query: 298 EVKTTRGGHSVVYSVYDMHEQFKEAGERLFNV--AWLAPKSANRRRNLAKPSLPPVTVHR 355
             +    G    Y++YD+ +       R  N+   W  P           P +P +   R
Sbjct: 299 TYQDVILGTRKTYAIYDLLDTAMINNSRNLNIQLKWKRPPENE------APPVPFLHAQR 352

Query: 356 YLLGHGQERGRIVTEVTNSH-YDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQR 414
           Y+ G+G ++G + T + N+H Y A P++L + +PWY+  Y+HTL+I  K        G+ 
Sbjct: 353 YVSGYGLQKGELSTLLYNTHPYRAFPVLLLDTVPWYLRLYVHTLTITSK--------GKE 404

Query: 415 LTFKLLHYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGS 474
                +HY P + R  P  LE+   LP  +   +SI  +  LLKW EY PD NHG Y+  
Sbjct: 405 NKPSYIHYQPAQDRLQPHLLEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSP 464

Query: 475 AIVSSQLPMGRNYTALPP-EGHLFEHSFNATRPS-YVLSLHTEALIVSLPTPDFSMPYNV 532
           +++S+ +P       +   E  LF   F  +  S Y + L+TE L+V+LPTPDFSMPYNV
Sbjct: 465 SVLSALVPSMVAAKPVDWEESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNV 524

Query: 533 ICLACTVVALAFGPIHSVATKMIIVGRQTSAPKNFVKKIFNQLFRRGK 580
           ICL CTVVA+ +G  +++ T+   +    +      K++ N L RR +
Sbjct: 525 ICLTCTVVAVCYGSFYNLLTRTFHIEEPRTG--GLAKRLAN-LIRRAR 569
>ref|NP_057021.1| (NM_015937) CGI-06 protein [Homo sapiens]
 gb|AAD27715.1|AF132940_1 (AF132940) CGI-06 protein [Homo sapiens]
          Length = 574

 Score =  889 bits (2273), Expect = 0.0
 Identities = 209/569 (36%), Positives = 313/569 (54%), Gaps = 30/569 (5%)

Query: 22  RDDERFHEELVVRPLSGDHVNTYFQFTTRWHYG-EKDNLYHTQLTPRVIAELLQQFAVKE 80
                  EELV+ PL    V   FQF TRW    +++ + H +L P+ + +L+ +++++E
Sbjct: 21  TPTRHLREELVITPLPSGDVAATFQFRTRWDSELQREGVSHYRLFPKALGQLISKYSLRE 80

Query: 81  LHIGLTQGLWRYETWGYPIVEATSGAEMWAWFSGANLTNRDVDRQWKELANVFSGVLCAS 140
           LH+  TQG WR   WG P ++A SGAE+W WF     T  DVD+ WKEL+NV SG+ CAS
Sbjct: 81  LHLSFTQGFWRTRYWGPPFLQAPSGAELWVWFQD---TVTDVDKSWKELSNVLSGIFCAS 137

Query: 141 LNFVDNTNSIAPRHLIRPQFMPANGQR-FVRYATLPREIVCTENLTPWKKLLPCGSASGF 199
           LNF+D+TN++ P    +P  +  +    F+RYA LPRE+VCTENLTPWKKLLPC S +G 
Sbjct: 138 LNFIDSTNTVTPTASFKPLGLANDTDHYFLRYAVLPREVVCTENLTPWKKLLPCSSKAGL 197

Query: 200 ASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTANLVYDLRLFELSNNDFSLR 259
           + LL +  + +T YHS  + +R +C +    +   EL QT ++V+D  +      D+SL 
Sbjct: 198 SVLLKADRLFHTSYHSQAVHIRPVCRNARCTSISWELRQTLSVVFDAFITGQGKKDWSLF 257

Query: 260 RLFGMGLNGYCELAESSKIYVQ---RNELGERYQLVPEPVHEVKTTRGGHSVVYSVYDMH 316
           R+F   L   C LA  S++YV     N+  E  ++ P P    +    G    Y++YD+ 
Sbjct: 258 RMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPPTTTYQDVILGTRKTYAIYDLL 317

Query: 317 EQFKEAGERLFNV--AWLAPKSANRRRNLAKPSLPPVTVHRYLLGHGQERGRIVTEVTNS 374
           +       R  N+   W  P           P +P +   RY+ G+G ++G + T + N+
Sbjct: 318 DTAMINNSRNLNIQLKWKRPPENE------APPVPFLHAQRYVSGYGLQKGELSTLLYNT 371

Query: 375 H-YDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFKLLHYTPGKQRELPSH 433
           H Y A P++L + +PWY+  Y+HTL+I  K        G+      +HY P + R  P  
Sbjct: 372 HPYRAFPVLLLDTVPWYLRLYVHTLTITSK--------GKENKPSYIHYQPAQDRLQPHL 423

Query: 434 LEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLPMGRNYTALPP- 492
           LE+   LP  +   +SI  +  LLKW EY PD NHG Y+  +++S+ +P       +   
Sbjct: 424 LEMLIQLPANSVTKVSIQFERALLKWTEYTPDPNHGFYVSPSVLSALVPSMVAAKPVDWE 483

Query: 493 EGHLFEHSFNATRPS-YVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFGPIHSVA 551
           E  LF   F  +  S Y + L+TE L+V+LPTPDFSMPYNVICL CTVVA+ +G  +++ 
Sbjct: 484 ESPLFNSLFPVSDGSNYFVRLYTEPLLVNLPTPDFSMPYNVICLTCTVVAVCYGSFYNLL 543

Query: 552 TKMIIVGRQTSAPKNFVKKIFNQLFRRGK 580
           T+   +    +      K++ N L RR +
Sbjct: 544 TRTFHIEEPRTG--GLAKRLAN-LIRRAR 569
>ref|NP_566299.1| (NM_111594) expressed protein [Arabidopsis thaliana]
 gb|AAK92821.1| (AY050884) unknown protein [Arabidopsis thaliana]
          Length = 644

 Score =  702 bits (1794), Expect = 0.0
 Identities = 184/631 (29%), Positives = 286/631 (45%), Gaps = 85/631 (13%)

Query: 4   VAFVLLLLVAPN---ADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYGEKDNLY 60
           +  ++LLL+  +   A A   ++ E F E L+++PL    V  +F F  R         +
Sbjct: 5   LRSLILLLIVQSFLVAIAFGSKEVEEFSEALLLKPLPDRKVLAHFHFENRAPPSNSHGRH 64

Query: 61  HTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGY--PIVEA---TSGAEMWAWFSGA 115
           H  L P+ I++L+Q+F VKE+ +  TQG W +E WG   P+        G E+WA F   
Sbjct: 65  H-HLFPKAISQLVQKFRVKEMELSFTQGRWNHEHWGGFDPLSSMNAKPVGVELWAVF--- 120

Query: 116 NLTNRDVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQRFVRYATLP 175
           ++    VD  WK L +  SG+ CAS+NF++++ S A      P +        +RY +LP
Sbjct: 121 DVPQSQVDTSWKNLTHALSGLFCASINFLESSTSYAA-----PTWGFGPNSDKLRYGSLP 175

Query: 176 REIVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVE 235
           RE VCTENLTPW KLLPC    G ++L+N   V+   YHS  L +  +    +     + 
Sbjct: 176 REAVCTENLTPWLKLLPCRDKDGISALMNRPSVYRGFYHSQRLHLSTVESGQEGLGSGIV 235

Query: 236 LTQTANLVYDLRLFELSNN---DFSLRRLFGMGLNGYCELAESSKIYVQ---------RN 283
           L QT  +V       + +N    +SL  LFG  + G C LA+SS +Y+Q         +N
Sbjct: 236 LEQTLTVVLQPETTSVESNMQPSWSLSSLFGRQVVGRCVLAKSSNVYLQLEGLLGYESKN 295

Query: 284 ELGE----------RYQLVPEPVHEVKTTRGGHSVVYSVYDMHEQFKEAGERLFNVAWLA 333
              E           ++L  +P    +           ++D+ ++  ++      + W  
Sbjct: 296 VDTEIEAHQLWKNAEFELSLKP----ERVIRESCSFLFIFDI-DKSSDSEPFDLGLTWKR 350

Query: 334 PKSANRRRNLAKPSLPPVTVHRYLLGHGQERGRIVT--------------EVTNSHYDAL 379
           P   + ++        P+   R+L+G G ERG I                ++TN      
Sbjct: 351 PSKWSCQQA-------PLHSSRFLMGSGNERGAIAILLKATESQEKLSGRDLTNGQCTIK 403

Query: 380 PIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFKLLHYTPGKQRELPSHLEIGFM 439
             +  ++ PWY+  Y HTL I    Q+  +        K ++ +P   +     +E+   
Sbjct: 404 ANI-FQIFPWYIKVYYHTLQIFVDQQQKTD----SEVLKKINVSPSTDKVSSGMMEMMLE 458

Query: 440 LPGQT-SALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLPMGRNYTALPPEGHLFE 498
           LP +  S  ISI+ D   L   EYPPDAN G  I SA++S   P          E     
Sbjct: 459 LPCEVKSVAISIEYDKGFLHIDEYPPDANQGFDIPSALIS--FPDHHASLDFQEELSNSP 516

Query: 499 HSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFGPIHSVATKMI--- 555
              +    S V S +TE L+V L TPDFSMPYNVI + CT+ AL FG + +V  + I   
Sbjct: 517 LLSSLKEKSLVRS-YTEVLLVPLTTPDFSMPYNVITITCTIFALYFGSLLNVLRRRIGEE 575

Query: 556 ------IVGRQTSAPKNFVKKIFNQLFRRGK 580
                   G++T   K  + +I  ++  RG+
Sbjct: 576 ERFLKSQAGKKTGGLKQLLSRITAKI--RGR 604
>gb|AAF20232.1|AC012395_19 (AC012395) unknown protein [Arabidopsis thaliana]
          Length = 639

 Score =  697 bits (1780), Expect = 0.0
 Identities = 182/626 (29%), Positives = 283/626 (45%), Gaps = 80/626 (12%)

Query: 4   VAFVLLLLVAPN---ADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYGEKDNLY 60
           +  ++LLL+  +   A A   ++ E F E L+++PL    V  +F F  R         +
Sbjct: 5   LRSLILLLIVQSFLVAIAFGSKEVEEFSEALLLKPLPDRKVLAHFHFENRAPPSNSHGRH 64

Query: 61  HTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGY--PIVEA---TSGAEMWAWFSGA 115
           H  L P+ I++L+Q+F VKE+ +  TQG W +E WG   P+        G E+WA F   
Sbjct: 65  H-HLFPKAISQLVQKFRVKEMELSFTQGRWNHEHWGGFDPLSSMNAKPVGVELWAVF--- 120

Query: 116 NLTNRDVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQRFVRYATLP 175
           ++    VD  WK L +  SG+ CAS+NF++++ S A      P +        +RY +LP
Sbjct: 121 DVPQSQVDTSWKNLTHALSGLFCASINFLESSTSYAA-----PTWGFGPNSDKLRYGSLP 175

Query: 176 REIVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVE 235
           RE VCTENLTPW KLLPC    G ++L+N   V+   YHS  L +  +    +     + 
Sbjct: 176 REAVCTENLTPWLKLLPCRDKDGISALMNRPSVYRGFYHSQRLHLSTVESGQEGLGSGIV 235

Query: 236 LTQTANLVYDLRLFELSNN---DFSLRRLFGMGLNGYCELAESSKIYVQ---------RN 283
           L QT  +V       + +N    +SL  LFG  + G C LA+SS +Y+Q         +N
Sbjct: 236 LEQTLTVVLQPETTSVESNMQPSWSLSSLFGRQVVGRCVLAKSSNVYLQLEGLLGYESKN 295

Query: 284 ELGE----------RYQLVPEPVHEVKTTRGGHSVVYSVYDMHEQFKEAGERLFNVAWLA 333
              E           ++L  +P    +           ++D+ ++  ++      + W  
Sbjct: 296 VDTEIEAHQLWKNAEFELSLKP----ERVIRESCSFLFIFDI-DKSSDSEPFDLGLTWKR 350

Query: 334 PKSANRRRNLAKPSLPPVTVHRYLLGHGQERGRIVT--------------EVTNSHYDAL 379
           P   + ++        P+   R+L+G G ERG I                ++TN      
Sbjct: 351 PSKWSCQQA-------PLHSSRFLMGSGNERGAIAILLKATESQEKLSGRDLTNGQCTIK 403

Query: 380 PIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFKLLHYTPGKQRELPSHLEIGFM 439
             +  ++ PWY+  Y HTL I    Q+  +        K ++ +P   +     +E+   
Sbjct: 404 ANI-FQIFPWYIKVYYHTLQIFVDQQQKTD----SEVLKKINVSPSTDKVSSGMMEMMLE 458

Query: 440 LPGQT-SALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLPMGRNYTALPPEGHLFE 498
           LP +  S  ISI+ D   L   EYPPDAN G  I SA++S   P          E     
Sbjct: 459 LPCEVKSVAISIEYDKGFLHIDEYPPDANQGFDIPSALIS--FPDHHASLDFQEELSNSP 516

Query: 499 HSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFGPIHSVATKMIIVG 558
              +    S V S +TE L+V L TPDFSMPYNVI + CT+ AL FG + +V  + I   
Sbjct: 517 LLSSLKEKSLVRS-YTEVLLVPLTTPDFSMPYNVITITCTIFALYFGSLLNVLRRRIGEE 575

Query: 559 RQ----TSAPKNFVKKIFNQLFRRGK 580
            +        K  + +I  ++  RG+
Sbjct: 576 ERFLKSQGGLKQLLSRITAKI--RGR 599
>ref|NP_012058.1| (NC_001140) Glycosyl Phosphatidyl Inositol 16; Gpi16p
           [Saccharomyces cerevisiae]
          Length = 610

 Score =  547 bits (1395), Expect = e-154
 Identities = 153/611 (25%), Positives = 258/611 (42%), Gaps = 102/611 (16%)

Query: 4   VAFVLLLLVAPNADANLGRDDERF---HEELVVRPLSGDHVNTYFQFTTRWHYGEK---- 56
           +  +LL + A +  + +G +D  +    E LV++PL  + +   F F  +    +     
Sbjct: 10  LGTLLLGVFAEDTVSQIGINDSLWYPYDEALVLKPLPNNDLLLSFAFQLQSEPFDPAVSS 69

Query: 57  ---DNLYHTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWG---YPIVEAT-SGAEMW 109
              D   H    PR I  LL+  A ++ H+  T+G W   +WG   +   EA  SG E+W
Sbjct: 70  MSYDAYEHYTTFPRAIPPLLESTATRQFHLRFTRGFWDALSWGQLPHAGKEAGASGVELW 129

Query: 110 AWFSGANLTNRDVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLI----RPQFMPANG 165
           +      +        WK+L+N  SG+ C+SLNF+D + +  PR             +  
Sbjct: 130 SQVQA--MDQEQAFHNWKKLSNSLSGLFCSSLNFIDESRTTFPRRSYASDIGAPLFNSTE 187

Query: 166 QRFVRYATLPREIVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCE 225
           + ++  A+LP E +CTENLTP+ KLLP    SG  SLL+   + ++ ++S+ L +  +C 
Sbjct: 188 KLYLMRASLPNEPICTENLTPFIKLLPTRGKSGLTSLLDGHKLFDSLWNSISLDIATICS 247

Query: 226 DHDEDNCIVELTQTANLV---------------------------------YDLRLF-EL 251
           + ++  C  E+     +V                                 Y      E 
Sbjct: 248 EDEDALCHYEMDARIEMVTHVPSALARGERPIPKPLDGNTLRCDTDKPFDSYQCFPLPEP 307

Query: 252 SNNDFSLRRLFGMGLNGYCELA-ESSKIYVQRNELGERYQLVPEPVHEVKTTRGGHSVVY 310
           S   F L +LF   +N     A   ++I  + +       L       V  T        
Sbjct: 308 SQTHFKLSQLFARPINNGNLFANRPTRICAEVDRSTWTAFLS------VDDTIFSTHD-- 359

Query: 311 SVYDMHEQFKEAGE-RLFNVAWLAPKSANRRRNLAKPSLP-PVTVHRYLLGHGQERGRIV 368
           + +D+     E G    F +        +       P +P P+ V R L G+GQ+RG + 
Sbjct: 360 NCFDLSNDQNEGGSGYDFILE-------STDTTKVTPIVPVPIHVSRSLTGNGQDRGGMR 412

Query: 369 TEVTNSHYDALPIMLQEVIPWYVHAYLHTLSIRRK---PQRVNEYGGQRLTFKLLHYTPG 425
               N +   + ++  E +PW++  YL +L I        + N+    +      +Y   
Sbjct: 413 IVFHNDNDTPVKLIYFESLPWFMRVYLSSLQITSTTSPQLQENDIILDK------YYLQA 466

Query: 426 KQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLPMGR 485
             R+ P HLE   ++P  T  +++   D  LL++ EYPPDANHG  I +A+++       
Sbjct: 467 ADRKRPGHLEFTMLIPANTDIVMTYQFDKALLQFAEYPPDANHGFEIDAAVITV------ 520

Query: 486 NYTALPPEGHLFEHSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFG 545
                           +    S +  + T  L++SL TPDFSMPYNVI L  T++ L FG
Sbjct: 521 ---------------LSLESSSSLYEMRTSTLLLSLSTPDFSMPYNVIILTSTIMGLIFG 565

Query: 546 PIHSVATKMII 556
            ++++  K ++
Sbjct: 566 MLYNLMVKRMV 576
>sp|P38875|YHY8_YEAST HYPOTHETICAL 67.8 KDA PROTEIN IN IKI1-ERG9 INTERGENIC REGION
 pir||S46687 hypothetical protein YHR188c - yeast (Saccharomyces cerevisiae)
 gb|AAB68365.1| (U00030) Yhr188cp [Saccharomyces cerevisiae]
          Length = 602

 Score =  547 bits (1395), Expect = e-154
 Identities = 153/611 (25%), Positives = 258/611 (42%), Gaps = 102/611 (16%)

Query: 4   VAFVLLLLVAPNADANLGRDDERF---HEELVVRPLSGDHVNTYFQFTTRWHYGEK---- 56
           +  +LL + A +  + +G +D  +    E LV++PL  + +   F F  +    +     
Sbjct: 2   LGTLLLGVFAEDTVSQIGINDSLWYPYDEALVLKPLPNNDLLLSFAFQLQSEPFDPAVSS 61

Query: 57  ---DNLYHTQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWG---YPIVEAT-SGAEMW 109
              D   H    PR I  LL+  A ++ H+  T+G W   +WG   +   EA  SG E+W
Sbjct: 62  MSYDAYEHYTTFPRAIPPLLESTATRQFHLRFTRGFWDALSWGQLPHAGKEAGASGVELW 121

Query: 110 AWFSGANLTNRDVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLI----RPQFMPANG 165
           +      +        WK+L+N  SG+ C+SLNF+D + +  PR             +  
Sbjct: 122 SQVQA--MDQEQAFHNWKKLSNSLSGLFCSSLNFIDESRTTFPRRSYASDIGAPLFNSTE 179

Query: 166 QRFVRYATLPREIVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCE 225
           + ++  A+LP E +CTENLTP+ KLLP    SG  SLL+   + ++ ++S+ L +  +C 
Sbjct: 180 KLYLMRASLPNEPICTENLTPFIKLLPTRGKSGLTSLLDGHKLFDSLWNSISLDIATICS 239

Query: 226 DHDEDNCIVELTQTANLV---------------------------------YDLRLF-EL 251
           + ++  C  E+     +V                                 Y      E 
Sbjct: 240 EDEDALCHYEMDARIEMVTHVPSALARGERPIPKPLDGNTLRCDTDKPFDSYQCFPLPEP 299

Query: 252 SNNDFSLRRLFGMGLNGYCELA-ESSKIYVQRNELGERYQLVPEPVHEVKTTRGGHSVVY 310
           S   F L +LF   +N     A   ++I  + +       L       V  T        
Sbjct: 300 SQTHFKLSQLFARPINNGNLFANRPTRICAEVDRSTWTAFLS------VDDTIFSTHD-- 351

Query: 311 SVYDMHEQFKEAGE-RLFNVAWLAPKSANRRRNLAKPSLP-PVTVHRYLLGHGQERGRIV 368
           + +D+     E G    F +        +       P +P P+ V R L G+GQ+RG + 
Sbjct: 352 NCFDLSNDQNEGGSGYDFILE-------STDTTKVTPIVPVPIHVSRSLTGNGQDRGGMR 404

Query: 369 TEVTNSHYDALPIMLQEVIPWYVHAYLHTLSIRRK---PQRVNEYGGQRLTFKLLHYTPG 425
               N +   + ++  E +PW++  YL +L I        + N+    +      +Y   
Sbjct: 405 IVFHNDNDTPVKLIYFESLPWFMRVYLSSLQITSTTSPQLQENDIILDK------YYLQA 458

Query: 426 KQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLPMGR 485
             R+ P HLE   ++P  T  +++   D  LL++ EYPPDANHG  I +A+++       
Sbjct: 459 ADRKRPGHLEFTMLIPANTDIVMTYQFDKALLQFAEYPPDANHGFEIDAAVITV------ 512

Query: 486 NYTALPPEGHLFEHSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFG 545
                           +    S +  + T  L++SL TPDFSMPYNVI L  T++ L FG
Sbjct: 513 ---------------LSLESSSSLYEMRTSTLLLSLSTPDFSMPYNVIILTSTIMGLIFG 557

Query: 546 PIHSVATKMII 556
            ++++  K ++
Sbjct: 558 MLYNLMVKRMV 568
>ref|NP_505797.1| (NM_073396) F17C11.7.p [Caenorhabditis elegans]
 pir||T21059 hypothetical protein F17C11.7 - Caenorhabditis elegans
 emb|CAA96629.1| (Z72507) Similarity with yeast hypothetical protein Swiss Prot
           accession number P38875 [Caenorhabditis elegans]
          Length = 531

 Score =  329 bits (835), Expect = 1e-88
 Identities = 78/262 (29%), Positives = 128/262 (48%), Gaps = 21/262 (8%)

Query: 25  ERFHEELVVRPLSGDHVNTYFQFTTRWHYGEKDNLYHTQLTPRVIAELLQQFAVKELHIG 84
           E F E+L + P+S + +   F+F +   +  K         PR+I ELL +++V++L + 
Sbjct: 21  ENFDEKLTLSPVSKNELRVDFRFNSEREFNRKTESGDYLTFPRIIQELLSRYSVRKLTVT 80

Query: 85  LTQGLWRYETWGYPIVE-ATSGAEMWAWFSGANLTNRDVDRQWKELANVFSGVLCASLNF 143
           +  G W    WG P    + +GA+++A F        D D + K L    +GVLC S++ 
Sbjct: 81  MAHGRWNLIGWGLPPQPSSPTGAQVFAEFEADQ--QEDADERMKFLVEALNGVLCTSISH 138

Query: 144 VDNTNSIAPRHLIRPQFMPANG---QRFV--RYATLPREIVCTENLTPWKKLLPCGSASG 198
           ++   S        P+F+       +  V  RY  L  E  CTENLT  +KLL C   +G
Sbjct: 139 INVITS--------PEFIVLKNHGGETSVHKRYGVLSGETTCTENLTRLRKLLACK-ENG 189

Query: 199 FASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELTQTANLVYDLRLFELSNNDFSL 258
            ++LL+   ++N+ YHS  L V   C   D+D C  ++    ++V      + +   +SL
Sbjct: 190 ISTLLHPSKLYNSVYHSSHLVVEQQC---DKDQCNSKMEVGVSVVMR-NPSQKTQRHWSL 245

Query: 259 RRLFGMGLNGYCELAESSKIYV 280
             +F   L   C++A SSKI+V
Sbjct: 246 ADVFERKLGSQCKVARSSKIHV 267
 Score =  223 bits (564), Expect = 6e-57
 Identities = 59/194 (30%), Positives = 91/194 (46%), Gaps = 33/194 (17%)

Query: 359 GHGQERGRIVTEVTNSHYDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFK 418
           G  Q+ G +   +TN    A  I + ++IP+YVH     L   +   + ++ G  R+   
Sbjct: 315 GFEQKHGVLTVHITNDE-SASEIHVSQIIPYYVH-----LRYSKINWKCDKNGVPRIE-- 366

Query: 419 LLHYTPGKQRELPSHLEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVS 478
            + +   K  E P+ L+    L    +  ++I  D  LL+  +YPPDANHG +I +A V 
Sbjct: 367 KI-FKNSKSLEAPTLLQYKMKLSAGQTCELTIPFDKQLLRLEQYPPDANHGMHIPAASVY 425

Query: 479 SQLPMGRNYTALPPEGHLFEHSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACT 538
            Q                        + +   ++H+ A++V LP PDFSMP+NVIC   T
Sbjct: 426 IQ------------------------KSTSTYTIHSNAILVLLPVPDFSMPFNVICFVAT 461

Query: 539 VVALAFGPIHSVAT 552
             AL FGPI   +T
Sbjct: 462 AFALVFGPIQLYST 475
>pir||T39499 conserved hypothetical protein SPBC1604.15 - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA22348.1| (AL034433) conserved hypothetical protein [Schizosaccharomyces
           pombe]
          Length = 545

 Score =  310 bits (787), Expect = 5e-83
 Identities = 79/267 (29%), Positives = 122/267 (45%), Gaps = 43/267 (16%)

Query: 314 DMHEQFKEAGERLFNVAWLAPKSANRRRNLAKPSLPPVTVHRYLLGHGQERGRIVTEVTN 373
           D  + F         +   +    +            VTV R L   G   G + + + N
Sbjct: 313 DKIDTFSLDEAANIQIPIQSTSDNHT-----------VTVDRSLSNDGNHWGSLSSTIYN 361

Query: 374 SHYDALPIMLQEVIPWYVHAYLHTLSIRRKPQRVNEYGGQRLTFKLLHYTPGKQRELPSH 433
                  I+  E  PW+V  YLHTL+I     R+N     +   + L+Y P + R+  + 
Sbjct: 362 PSSSPRTIVYFEKFPWFVRVYLHTLTITLNGTRIN----TKDFIEKLYYQPLRDRKAGTM 417

Query: 434 LEIGFMLPGQTSALISIDVDYLLLKWLEYPPDANHGHYIGSAIVSSQLPMGRNYTALPPE 493
           +EI F +P  T+ ++  +V+   L+  EYPPDAN G+ +  AI+S               
Sbjct: 418 MEIQFSIPPHTNLIVHFNVEKTPLRLDEYPPDANRGYNLPPAIISV-------------- 463

Query: 494 GHLFEHSFNATRPSYVLSLHTEALIVSLPTPDFSMPYNVICLACTVVALAFGPIHSVATK 553
              F+   N T+   + SL T AL++ +PTPDFSMPYNVI    TV+AL FG I ++ T+
Sbjct: 464 ---FDE--NNTK---LCSLRTAALLMFIPTPDFSMPYNVIIFTSTVIALTFGGIFNLLTR 515

Query: 554 MII------VGRQTSAPKNFVKKIFNQ 574
             +        RQ S  +   +KIF++
Sbjct: 516 RFVPQQSKFQNRQPSMLQRLKEKIFHK 542
 Score =  310 bits (786), Expect = 7e-83
 Identities = 77/256 (30%), Positives = 118/256 (46%), Gaps = 21/256 (8%)

Query: 9   LLLVAPNADAN---LGRDDERFHEELVVRPLSGDHVNTYFQFT----TRWHYGEKDNLYH 61
           LLL A +  +        DE + E L ++  S  +    F F     T   +    +   
Sbjct: 7   LLLFAYSLLSFSLTAATIDETYDESLFIKSFSSRYSYVSFAFEIGASTDSTHSSVFSESS 66

Query: 62  TQLTPRVIAELLQQFAVKELHIGLTQGLWRYETWGYP----IVEATSGAEMWAWFSGANL 117
             L P  IA ++ +  V ELHI  T+G W YE W             G E+WA+     +
Sbjct: 67  FSLFPLSIARVMDECQVSELHIRATRGRWDYENWKESPDNGFYSGGLGFEVWAF-----M 121

Query: 118 TNRDVDRQWKELANVFSGVLCASLNFVDNTNSIAPRHLIRPQFMPANGQRFVRYATLPRE 177
            N    + W +L N  SG+LCASLN++D++N+  P+      F  +N  ++  +A+LP+E
Sbjct: 122 ANDPSMKYWLKLTNQLSGLLCASLNYIDSSNTYQPQLSYPGSFSFSNNTQY--FASLPQE 179

Query: 178 IVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVLCEDHDEDNCIVELT 237
            VCTENL+P  KLLPC   +G ASLL+S    +T +HS  + V       ++    V++ 
Sbjct: 180 DVCTENLSPLFKLLPCKRKAGIASLLDSHLFFDTDWHSFSIDVYP---SENQSLASVKMG 236

Query: 238 QTANLVYDLRLFELSN 253
                V D+       
Sbjct: 237 IIIQAVVDVERNGRRK 252
>emb|CAC36338.1| (AL021578) dJ453C12.7.3 (CGI-06 protein (LOC51604), isoform 3)
           [Homo sapiens]
          Length = 238

 Score =  303 bits (770), Expect = 4e-81
 Identities = 61/169 (36%), Positives = 90/169 (53%), Gaps = 3/169 (1%)

Query: 164 NGQRFVRYATLPREIVCTENLTPWKKLLPCGSASGFASLLNSGHVHNTKYHSLGLKVRVL 223
               F+RYA LPRE+VCTENLTPWKKLLPC S +G + LL +  + +T YHS  + +R +
Sbjct: 68  TDHYFLRYAVLPREVVCTENLTPWKKLLPCSSKAGLSVLLKADRLFHTSYHSQAVHIRPV 127

Query: 224 CEDHDEDNCIVELTQTANLVYDLRLFELSNNDFSLRRLFGMGLNGYCELAESSKIYVQ-- 281
           C +    +   EL QT ++V+D  +      D+SL R+F   L   C LA  S++YV   
Sbjct: 128 CRNARCTSISWELRQTLSVVFDAFITGQGKKDWSLFRMFSRTLTEPCPLASESRVYVDIT 187

Query: 282 -RNELGERYQLVPEPVHEVKTTRGGHSVVYSVYDMHEQFKEAGERLFNV 329
             N+  E  ++ P P    +    G    Y++YD+ +       R  N+
Sbjct: 188 TYNQDNETLEVHPPPTTTYQDVILGTRKTYAIYDLLDTAMINNSRNLNI 236
 Score = 74.8 bits (182), Expect = 4e-12
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)

Query: 3  PVAFVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYG-EKDNL-Y 60
          P+A ++LLL+ P          +   EELV+ PL    V   FQF TRW    +++    
Sbjct: 10 PLALLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQREGDTD 69

Query: 61 HTQL 64
          H  L
Sbjct: 70 HYFL 73
>emb|CAC36339.1| (AL021578) dJ453C12.7.2 (CGI-06 protein (LOC51604), isoform 2)
           [Homo sapiens]
          Length = 107

 Score = 97.4 bits (240), Expect = 6e-19
 Identities = 16/57 (28%), Positives = 24/57 (42%), Gaps = 3/57 (5%)

Query: 251 LSNNDFSLRRLFGMGLNGYCELAESSKIYVQ---RNELGERYQLVPEPVHEVKTTRG 304
               D+SL R+F   L   C LA  S++YV     N+  E  ++ P P    +    
Sbjct: 51  QREGDWSLFRMFSRTLTEPCPLASESRVYVDITTYNQDNETLEVHPPPTTTYQDVIL 107
 Score = 69.7 bits (169), Expect = 1e-10
 Identities = 19/68 (27%), Positives = 30/68 (43%), Gaps = 2/68 (2%)

Query: 6  FVLLLLVAPNADANLGRDDERFHEELVVRPLSGDHVNTYFQFTTRWHYG-EKDNL-YHTQ 63
           ++LLL+ P          +   EELV+ PL    V   FQF TRW    +++      +
Sbjct: 1  LLVLLLLGPGGWCLAEPPRDSLREELVITPLPSGDVAATFQFRTRWDSELQREGDWSLFR 60

Query: 64 LTPRVIAE 71
          +  R + E
Sbjct: 61 MFSRTLTE 68
CPU time:   128.77 user secs.	    2.39 sys. secs	  131.16 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.310    0.162    0.477 

Gapped
Lambda     K      H
   0.270   0.0568    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 362498996
Number of Sequences: 887402
Number of extensions: 15987150
Number of successful extensions: 55367
Number of sequences better than 10.0: 35
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 55212
Number of HSP's gapped (non-prelim): 61
length of query: 633
length of database: 277,845,442
effective HSP length: 56
effective length of query: 577
effective length of database: 228,150,930
effective search space: 131643086610
effective search space used: 131643086610
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.0 bits)
S2: 76 (33.7 bits)