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GPI Biosynthesis Report< | |
| GPI Biosynthesis Main Page | GPI Site Motif | GPI Site Prediction | Home Page B.E. |
| Molecular Function: | part of the transamidase complex |
|---|---|
| Complex: | GPAA1/GAA1, PIG-K/GPI8, PIG-S/GPI17, PIG-T/GPI16 |
| Cellular Localization: | ER membrane |
| Domain Architecture: | (cytosol) N --|TM|-----lumenal part-----|TM|-- C (cytosol) |
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Orthologues |  |
|---|
| Protein | Organism | Sequence Length | GenBank Entry |
| EAA07616.1 | Anopheles gambiae | 590 | gi|21295471| |
| NP_187374.1 | Arabidopsis thaliana | 605 | gi|15231410| |
| AN5150.1 | Aspergillus nidulans | 551 | |
| T24913 | Caenorhabditis elegans | 544 | gi|7507837| |
| orf19.6379.prot | Candida albicans | 152 | |
| AAL27645.1 | Drosophila melanogaster | 536 | gi|16902036| |
| NP_149975.1 | Homo sapiens | 555 | gi|15088795| |
| XP_203412.1 | Mus musculus | 555 | gi|25025833| |
| XP_325888.1 | Neurospora crassa | 568 | gi|32410815| |
| BAB92563.1 | Oryza sativa (japonica cultivar-group) | 557 | gi|20804882| |
| NP_010722.1 | Saccharomyces cerevisiae | 534 | gi|6320642| |
| Q10351 | Schizosaccharomyces pombe | 554 | gi|1723513| |
Fasta-File of the Family-Members
| Alignments PIG-S: |
- MView - Clustal |
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Literature | |
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| PubMed: 11483512 | PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8. EMBO J 2001 Aug 1;20(15):4088-98 |
Author: Birgit.Eisenhaber@nt.imp.univie.ac.at on internet.