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GPI Anchor Biosynthesis Report: PIG-S family

Molecular Function: part of the transamidase complex
Cellular Localization:ER membrane
Domain Architecture: (cytosol) N --|TM|-----lumenal part-----|TM|-- C (cytosol)

Protein Organism Sequence Length GenBank Entry
EAA07616.1 Anopheles gambiae 590 gi|21295471|
NP_187374.1 Arabidopsis thaliana 605 gi|15231410|
AN5150.1 Aspergillus nidulans 551  
T24913 Caenorhabditis elegans 544 gi|7507837|
orf19.6379.prot Candida albicans 152  
AAL27645.1 Drosophila melanogaster 536 gi|16902036|
NP_149975.1 Homo sapiens 555 gi|15088795|
XP_203412.1 Mus musculus 555 gi|25025833|
XP_325888.1 Neurospora crassa 568 gi|32410815|
BAB92563.1 Oryza sativa (japonica cultivar-group) 557 gi|20804882|
NP_010722.1 Saccharomyces cerevisiae 534 gi|6320642|
Q10351 Schizosaccharomyces pombe 554 gi|1723513|

Fasta-File of the Family-Members

Alignments PIG-S: - MView
- Clustal

PubMed: 11483512 PIG-S and PIG-T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8.
EMBO J 2001 Aug 1;20(15):4088-98

Author: on internet.
Last modified: 26th November 2003