Sequences with E-value BETTER than threshold (0.002) 262 3e-69
195 2e-49
147 1e-34
146 1e-34
146 2e-34
146 2e-34
145 4e-34
126 2e-28
115 4e-25
114 6e-25
109 3e-23
99 6e-20
97 2e-19
64 1e-09
Sequences with E-value WORSE than threshold gb|AAF56563.1| (AE003754) CG14550 gene product [Drosophila melan... 39 0.060
Alignments
>pir||T38153 hypothetical protein SPAC22A12.13 - fission yeast
(Schizosaccharomyces pombe)
Length = 157
Score = 262 bits (663), Expect = 3e-69
Identities = 157/157 (100%), Positives = 157/157 (100%)
Query: 1 MLVPPSPSLTTMFRTRSTTPDEEGTAIAEIDQQDWDIMVKVPTYEYYGFVMYLVSMLGFG 60
MLVPPSPSLTTMFRTRSTTPDEEGTAIAEIDQQDWDIMVKVPTYEYYGFVMYLVSMLGFG
Sbjct: 1 MLVPPSPSLTTMFRTRSTTPDEEGTAIAEIDQQDWDIMVKVPTYEYYGFVMYLVSMLGFG 60
Query: 61 VYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSSL 120
VYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSSL
Sbjct: 61 VYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSSL 120
Query: 121 ECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET 157
ECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET
Sbjct: 121 ECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET 157
>emb|CAB16583.2| (Z99295) human downs syndrome critical region-like
[Schizosaccharomyces pombe]
Length = 120
Score = 195 bits (493), Expect = 2e-49
Identities = 120/120 (100%), Positives = 120/120 (100%)
Query: 38 MVKVPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVL 97
MVKVPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVL
Sbjct: 1 MVKVPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVL 60
Query: 98 VIYIHVVLNAYNTEVLTKPFSSLECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET 157
VIYIHVVLNAYNTEVLTKPFSSLECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET
Sbjct: 61 VIYIHVVLNAYNTEVLTKPFSSLECIVDQYALVGEEDGAAHGRVVDLRLCDVNKQQLEET 120
>ref|NP_062416.1| (NM_019543) Down syndrome critical region protein c [Mus musculus]
gb|AAF32294.1|AF216306_1 (AF216306) DCRC-1 [Mus musculus]
gb|AAF32295.1|AF216307_1 (AF216307) DCRC-2 [Mus musculus]
gb|AAF32296.1|AF216308_1 (AF216308) DCRC-3 [Mus musculus]
gb|AAF32297.1|AF216309_1 (AF216309) DCRC-4 [Mus musculus]
dbj|BAB23204.1| (AK004169) Down syndrome critical region gene c~data source:MGD,
source key:MGI:1860433, evidence:ISS~putative [Mus
musculus]
Length = 132
Score = 147 bits (369), Expect = 1e-34
Identities = 32/88 (36%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 41 VPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIY 100
+P YGFV++L S GF +Y+VWA P L + Y+ ++WA+A+P +L + V+
Sbjct: 9 LPERAIYGFVLFLSSQFGFILYLVWAFVPESWLNSLGLTYWPQKYWAVALPVYLLITVVI 68
Query: 101 IHVVLNAYNTEVLTKPFSSLECIVDQYA 128
+V+L N + T P S+ I D YA
Sbjct: 69 GYVLLFGINM-MSTSPLDSIHTITDNYA 95
>sp|P57054|DSR5_HUMAN Down syndrome critical region protein 5 (Down syndrome critical
region protein C)
dbj|BAA96872.1| (AB037163) DSCR5b [Homo sapiens]
Length = 158
Score = 146 bits (367), Expect = 1e-34
Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 41 VPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIY 100
+P YGFV++L S GF +Y+VWA P L + Y+ ++WA+A+P +L + ++
Sbjct: 33 LPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVI 92
Query: 101 IHVVLNAYNTEVLTKPFSSLECIVDQYA 128
+V+L N + T P S+ I D YA
Sbjct: 93 GYVLLFGINM-MSTSPLDSIHTITDNYA 119
>dbj|BAA95636.1| (AB035745) DSCR5b [Homo sapiens]
gb|AAG09757.1|AF237812_1 (AF237812) NPD010 [Homo sapiens]
Length = 158
Score = 146 bits (367), Expect = 2e-34
Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 41 VPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIY 100
+P YGFV++L S GF +Y+VWA P L + Y+ ++WA+A+P +L + ++
Sbjct: 33 LPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVI 92
Query: 101 IHVVLNAYNTEVLTKPFSSLECIVDQYA 128
+V+L N + T P S+ I D YA
Sbjct: 93 GYVLLFGINM-MSTSPLDSIHTITDNYA 119
>pir||JC7302 Down syndrome critical region protein 5 beta - human
Length = 158
Score = 146 bits (367), Expect = 2e-34
Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 41 VPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIY 100
+P YGFV++L S GF +Y+VWA P L + Y+ ++WA+A+P +L + ++
Sbjct: 33 LPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVI 92
Query: 101 IHVVLNAYNTEVLTKPFSSLECIVDQYA 128
+V+L N + T P S+ I D YA
Sbjct: 93 GYVLLFGLNM-MSTSPLDSIHTITDNYA 119
>pir||JC7301 Down syndrome critical region protein 5 alpha - human
dbj|BAA95633.1| (AB035742) DSCR5a1 [Homo sapiens]
dbj|BAA95634.1| (AB035743) DSCR5a2 [Homo sapiens]
dbj|BAA95635.1| (AB035744) DSCR5a3 [Homo sapiens]
dbj|BAA96871.1| (AB037162) DSCR5a [Homo sapiens]
dbj|BAB12395.1| (AB039659) PIG-P [Homo sapiens]
gb|AAH05180.1|AAH05180 (BC005180) Unknown (protein for MGC:12168) [Homo sapiens]
gb|AAH11007.1|AAH11007 (BC011007) Unknown (protein for MGC:13327) [Homo sapiens]
Length = 134
Score = 145 bits (364), Expect = 4e-34
Identities = 31/88 (35%), Positives = 50/88 (56%), Gaps = 1/88 (1%)
Query: 41 VPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIY 100
+P YGFV++L S GF +Y+VWA P L + Y+ ++WA+A+P +L + ++
Sbjct: 9 LPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVI 68
Query: 101 IHVVLNAYNTEVLTKPFSSLECIVDQYA 128
+V+L N + T P S+ I D YA
Sbjct: 69 GYVLLFGINM-MSTSPLDSIHTITDNYA 95
>ref|NP_176323.1| (NM_104809) hypothetical protein [Arabidopsis thaliana]
sp|O64792|DSR5_ARATH Down syndrome critical region protein 5 homolog
gb|AAC13913.1|AAC13913 (AC004255) T1F9.23 [Arabidopsis thaliana]
Length = 137
Score = 126 bits (315), Expect = 2e-28
Identities = 26/86 (30%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 43 TYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIH 102
T E YGFV + ++ ++++W P L+ I+YY S++WA+A+P + V ++
Sbjct: 13 TSEVYGFVGSISIVVATVIFLIWGYVPDKFLESIGIYYYPSKYWAMAMPMYSMVTLLVAL 72
Query: 103 VVLNAYNTEVLTKPFSSLECIVDQYA 128
V N +KP +SL + D Y+
Sbjct: 73 VFYIGLNFMSTSKP-TSLNTLFDDYS 97
>ref|NP_057514.1| (NM_016430) Down syndrome critical region protein 5; Down syndrome
critical region protein C short form; Down syndrome
critical region protein C [Homo sapiens]
gb|AAF32289.1|AF216305_1 (AF216305) Down syndrome critical region protein C short form [Homo
sapiens]
dbj|BAA96873.1| (AB037164) DSCR5c [Homo sapiens]
Length = 108
Score = 115 bits (287), Expect = 4e-25
Identities = 23/69 (33%), Positives = 38/69 (54%), Gaps = 1/69 (1%)
Query: 60 GVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSS 119
+Y+VWA P L + Y+ ++WA+A+P +L + V+ +V+L N + T P S
Sbjct: 2 VLYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAVVIGYVLLFGINM-MSTSPLDS 60
Query: 120 LECIVDQYA 128
+ I D YA
Sbjct: 61 IHTITDNYA 69
>dbj|BAA95512.1| (AP001727) Down syndrome critical region protein C [Homo sapiens]
Length = 108
Score = 114 bits (285), Expect = 6e-25
Identities = 22/69 (31%), Positives = 38/69 (54%), Gaps = 1/69 (1%)
Query: 60 GVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSS 119
+Y+VWA P L + Y+ ++WA+A+P +L + ++ +V+L N + T P S
Sbjct: 2 VLYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYVLLFGINM-MSTSPLDS 60
Query: 120 LECIVDQYA 128
+ I D YA
Sbjct: 61 IHTITDNYA 69
>ref|NP_010725.1| (NC_001136) Protein required for cell viability; Ydr437wp
[Saccharomyces cerevisiae]
pir||S69717 hypothetical protein YDR437w - yeast (Saccharomyces cerevisiae)
gb|AAB64854.1| (U33007) Ydr437wp; CAI: 0.10 [Saccharomyces cerevisiae]
Length = 140
Score = 109 bits (271), Expect = 3e-23
Identities = 20/91 (21%), Positives = 41/91 (44%), Gaps = 9/91 (9%)
Query: 43 TYEYYGFVMYLVSMLGFGVYIVWALTPAP--------VLKFFEIHYYLSRWWALAIPTWL 94
T EYY F Y++ + I+W++ P+ + + + R W + + + +
Sbjct: 3 TKEYYWFSQYMIITSTLVLTIIWSILPSSLGEAAPKQFINTL-LDIFPQRRWIITLESIM 61
Query: 95 FVLVIYIHVVLNAYNTEVLTKPFSSLECIVD 125
+ ++ ++ L YN + LT P SL + D
Sbjct: 62 LMGMLCTYIGLLMYNEDTLTPPLDSLSTVTD 92
>ref|NP_496845.1| (NM_064444) BR-1 protein-like [Caenorhabditis elegans]
emb|CAB07689.2| (Z93393) contains similarity to Pfam domain: PF01926 (GTPase of
unknown function), E-value=0.00012,~cDNA EST
EMBL:AU111138 comes from this gene~cDNA EST
EMBL:AU114976 comes from this gene [Caenorhabditis
elegans]
Length = 890
Score = 98.6 bits (243), Expect = 6e-20
Identities = 25/62 (40%), Positives = 36/62 (57%), Gaps = 1/62 (1%)
Query: 42 PTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYI 101
P YGF +Y+VS F +Y++WA+TP P+L I Y S+ WALAI + F +
Sbjct: 30 PARGIYGFALYIVSWTLFVIYLIWAITPVPILYRLGITYIPSKLWALAIGIF-FPTAACL 88
Query: 102 HV 103
+V
Sbjct: 89 YV 90
>pir||T27023 hypothetical protein Y48E1B.2a - Caenorhabditis elegans
Length = 1768
Score = 96.6 bits (238), Expect = 2e-19
Identities = 25/62 (40%), Positives = 36/62 (57%), Gaps = 1/62 (1%)
Query: 42 PTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYLSRWWALAIPTWLFVLVIYI 101
P YGF +Y+VS F +Y++WA+TP P+L I Y S+ WALAI + F +
Sbjct: 30 PARGIYGFALYIVSWTLFVIYLIWAITPVPILYRLGITYIPSKLWALAIGIF-FPTAACL 88
Query: 102 HV 103
+V
Sbjct: 89 YV 90
>ref|NP_181476.1| (NM_129502) hypothetical protein [Arabidopsis thaliana]
pir||T00554 hypothetical protein F12L6.10 - Arabidopsis thaliana
gb|AAC27835.1| (AC004218) hypothetical protein [Arabidopsis thaliana]
Length = 773
Score = 64.3 bits (155), Expect = 1e-09
Identities = 11/39 (28%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 90 IPTWLFVLVIYIHVVLNAYNTEVLTKPFSSLECIVDQYA 128
+PT+L V ++ N + T P +SL + D+Y+
Sbjct: 1 MPTYLMVTLMLALAFYIGLNF-IATPPPTSLNTLFDEYS 38
>gb|AAF56563.1| (AE003754) CG14550 gene product [Drosophila melanogaster]
Length = 138
Score = 38.6 bits (89), Expect = 0.060
Identities = 18/75 (24%), Positives = 35/75 (46%), Gaps = 7/75 (9%)
Query: 53 LVSMLGFGVYIVWALTPAPVLKFFEIH-YYLSRWWALAIPTWLFV-LVIYIHVVLNAYNT 110
++ + F VY+ WAL P +H Y +++A+ +P + V + ++ A N
Sbjct: 1 MLFTVLFLVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINL 56
Query: 111 EVLTKPFSSLECIVD 125
+ T S+ +VD
Sbjct: 57 SM-TVDVDSIASVVD 70
CPU time: 44.37 user secs. 1.73 sys. secs 46.10 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.319 0.160 0.492
Gapped
Lambda K H
0.270 0.0560 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106723385
Number of Sequences: 887402
Number of extensions: 5100822
Number of successful extensions: 18670
Number of sequences better than 10.0: 49
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 18637
Number of HSP's gapped (non-prelim): 53
length of query: 157
length of database: 277,845,442
effective HSP length: 49
effective length of query: 108
effective length of database: 234,362,744
effective search space: 25311176352
effective search space used: 25311176352
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.1 bits)
S2: 70 (31.4 bits)
