Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments:
gb|AAF56563.1| (AE003754) CG14550 gene product [Drosophila melan... 247 4e-65
Sequences with E-value WORSE than threshold
dbj|BAB56104.1| (AB028932) GLP1 [Homo sapiens] 36 0.25
gb|AAH11608.1|AAH11608 (BC011608) Unknown (protein for IMAGE:316... 36 0.29
dbj|BAB47505.1| (AB058779) KIAA1876 protein [Homo sapiens] 36 0.29
sp|P57054|DSR5_HUMAN Down syndrome critical region protein 5 (Do... 34 0.83
pir||JC7301 Down syndrome critical region protein 5 alpha - huma... 34 0.90
dbj|BAA95636.1| (AB035745) DSCR5b [Homo sapiens] >gi|9963906|gb|... 34 0.95
pir||JC7302 Down syndrome critical region protein 5 beta - human 33 1.9
ref|NP_062416.1| (NM_019543) Down syndrome critical region prote... 33 2.9
ref|NP_347063.1| (NC_003030) Fusion: PTS system, beta-glucosides... 33 3.2
dbj|BAA95512.1| (AP001727) Down syndrome critical region protein... 33 3.4
ref|NP_057514.1| (NM_016430) Down syndrome critical region prote... 33 3.7
Alignments
>gb|AAF56563.1| (AE003754) CG14550 gene product [Drosophila melanogaster]
Length = 138
Score = 247 bits (626), Expect = 4e-65
Identities = 138/138 (100%), Positives = 138/138 (100%)
Query: 1 MLFTVLFLVYVTWALLPVEFGLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTV 60
MLFTVLFLVYVTWALLPVEFGLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTV
Sbjct: 1 MLFTVLFLVYVTWALLPVEFGLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTV 60
Query: 61 DVDSIASVVDPKLALPKGTEFTSWSQLQKGKVSQDSASKKASPVNCNLCRTFHQPVTRAP 120
DVDSIASVVDPKLALPKGTEFTSWSQLQKGKVSQDSASKKASPVNCNLCRTFHQPVTRAP
Sbjct: 61 DVDSIASVVDPKLALPKGTEFTSWSQLQKGKVSQDSASKKASPVNCNLCRTFHQPVTRAP 120
Query: 121 IPPLRFLDLQEVNTAYYN 138
IPPLRFLDLQEVNTAYYN
Sbjct: 121 IPPLRFLDLQEVNTAYYN 138
>dbj|BAB56104.1| (AB028932) GLP1 [Homo sapiens]
Length = 917
Score = 36.4 bits (83), Expect = 0.25
Identities = 19/53 (35%), Positives = 26/53 (48%)
Query: 84 WSQLQKGKVSQDSASKKASPVNCNLCRTFHQPVTRAPIPPLRFLDLQEVNTAY 136
WS LQ K QDSA + SPV + R + R PIP + +D + + Y
Sbjct: 605 WSALQMSKALQDSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNY 657
>gb|AAH11608.1|AAH11608 (BC011608) Unknown (protein for IMAGE:3161748) [Homo sapiens]
Length = 719
Score = 36.0 bits (82), Expect = 0.29
Identities = 19/53 (35%), Positives = 26/53 (48%)
Query: 84 WSQLQKGKVSQDSASKKASPVNCNLCRTFHQPVTRAPIPPLRFLDLQEVNTAY 136
WS LQ K QDSA + SPV + R + R PIP + +D + + Y
Sbjct: 407 WSALQMSKALQDSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNY 459
>dbj|BAB47505.1| (AB058779) KIAA1876 protein [Homo sapiens]
Length = 552
Score = 36.0 bits (82), Expect = 0.29
Identities = 19/53 (35%), Positives = 26/53 (48%)
Query: 84 WSQLQKGKVSQDSASKKASPVNCNLCRTFHQPVTRAPIPPLRFLDLQEVNTAY 136
WS LQ K QDSA + SPV + R + R PIP + +D + + Y
Sbjct: 354 WSALQMSKALQDSAPDRPSPVERIVSRDIARGYERIPIPCVNAVDSEPCPSNY 406
>sp|P57054|DSR5_HUMAN Down syndrome critical region protein 5 (Down syndrome critical
region protein C)
dbj|BAA96872.1| (AB037163) DSCR5b [Homo sapiens]
Length = 158
Score = 34.5 bits (78), Expect = 0.83
Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 6/68 (8%)
Query: 7 FLVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTVDV 62
F++Y+ WA +P + GL +Y P KY+AV +P +L+ A +++ IN+ T +
Sbjct: 51 FILYLVWAFIPESWLNSLGL-TYWPQKYWAVALPVYLLI-AIVIGYVLLFGINMMSTSPL 108
Query: 63 DSIASVVD 70
DSI ++ D
Sbjct: 109 DSIHTITD 116
>pir||JC7301 Down syndrome critical region protein 5 alpha - human
dbj|BAA95633.1| (AB035742) DSCR5a1 [Homo sapiens]
dbj|BAA95634.1| (AB035743) DSCR5a2 [Homo sapiens]
dbj|BAA95635.1| (AB035744) DSCR5a3 [Homo sapiens]
dbj|BAA96871.1| (AB037162) DSCR5a [Homo sapiens]
dbj|BAB12395.1| (AB039659) PIG-P [Homo sapiens]
gb|AAH05180.1|AAH05180 (BC005180) Unknown (protein for MGC:12168) [Homo sapiens]
gb|AAH11007.1|AAH11007 (BC011007) Unknown (protein for MGC:13327) [Homo sapiens]
Length = 134
Score = 34.5 bits (78), Expect = 0.90
Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 6/68 (8%)
Query: 7 FLVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTVDV 62
F++Y+ WA +P + GL +Y P KY+AV +P +L+ A +++ IN+ T +
Sbjct: 27 FILYLVWAFIPESWLNSLGL-TYWPQKYWAVALPVYLLI-AIVIGYVLLFGINMMSTSPL 84
Query: 63 DSIASVVD 70
DSI ++ D
Sbjct: 85 DSIHTITD 92
>dbj|BAA95636.1| (AB035745) DSCR5b [Homo sapiens]
gb|AAG09757.1|AF237812_1 (AF237812) NPD010 [Homo sapiens]
Length = 158
Score = 34.5 bits (78), Expect = 0.95
Identities = 23/68 (33%), Positives = 40/68 (58%), Gaps = 6/68 (8%)
Query: 7 FLVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTVDV 62
F++Y+ WA +P + GL +Y P KY+AV +P +L+ A +++ IN+ T +
Sbjct: 51 FILYLVWAFIPESWLNSLGL-TYWPQKYWAVALPVYLLI-AIVIGYVLLFGINMMSTSPL 108
Query: 63 DSIASVVD 70
DSI ++ D
Sbjct: 109 DSIHTITD 116
>pir||JC7302 Down syndrome critical region protein 5 beta - human
Length = 158
Score = 33.3 bits (75), Expect = 1.9
Identities = 22/68 (32%), Positives = 40/68 (58%), Gaps = 6/68 (8%)
Query: 7 FLVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTVDV 62
F++Y+ WA +P + GL +Y P KY+AV +P +L+ A +++ +N+ T +
Sbjct: 51 FILYLVWAFIPESWLNSLGL-TYWPQKYWAVALPVYLLI-AIVIGYVLLFGLNMMSTSPL 108
Query: 63 DSIASVVD 70
DSI ++ D
Sbjct: 109 DSIHTITD 116
>ref|NP_062416.1| (NM_019543) Down syndrome critical region protein c [Mus
musculus]
gb|AAF32294.1|AF216306_1 (AF216306) DCRC-1 [Mus musculus]
gb|AAF32295.1|AF216307_1 (AF216307) DCRC-2 [Mus musculus]
gb|AAF32296.1|AF216308_1 (AF216308) DCRC-3 [Mus musculus]
gb|AAF32297.1|AF216309_1 (AF216309) DCRC-4 [Mus musculus]
dbj|BAB23204.1| (AK004169) Down syndrome critical region gene c~data source:MGD,
source key:MGI:1860433, evidence:ISS~putative [Mus
musculus]
Length = 132
Score = 32.9 bits (74), Expect = 2.9
Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 6/68 (8%)
Query: 7 FLVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTVDV 62
F++Y+ WA +P + GL +Y P KY+AV +P +L+ +++ IN+ T +
Sbjct: 27 FILYLVWAFVPESWLNSLGL-TYWPQKYWAVALPVYLLITV-VIGYVLLFGINMMSTSPL 84
Query: 63 DSIASVVD 70
DSI ++ D
Sbjct: 85 DSIHTITD 92
>ref|NP_347063.1| (NC_003030) Fusion: PTS system, beta-glucosides specific IIABC
component [Clostridium acetobutylicum]
gb|AAF35839.1|AF205034_2 (AF205034) ScrA [Clostridium acetobutylicum]
gb|AAK78403.1|AE007557_2 (AE007557) Fusion: PTS system, beta-glucosides specific IIABC
component [Clostridium acetobutylicum]
Length = 627
Score = 32.5 bits (73), Expect = 3.2
Identities = 15/47 (31%), Positives = 25/47 (52%)
Query: 4 TVLFLVYVTWALLPVEFGLHSYLPDKYFAVFVPFLVLVFAWFFAFLI 50
TVL ++ W + +E GL +P+ + PFL L+ FFA ++
Sbjct: 220 TVLPILISVWVMSYIEKGLRKIVPEALDILLTPFLTLMITGFFAMVV 266
>dbj|BAA95512.1| (AP001727) Down syndrome critical region protein C [Homo sapiens]
Length = 108
Score = 32.5 bits (73), Expect = 3.4
Identities = 22/67 (32%), Positives = 39/67 (57%), Gaps = 6/67 (8%)
Query: 8 LVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTVDVD 63
++Y+ WA +P + GL +Y P KY+AV +P +L+ A +++ IN+ T +D
Sbjct: 2 VLYLVWAFIPESWLNSLGL-TYWPQKYWAVALPVYLLI-AIVIGYVLLFGINMMSTSPLD 59
Query: 64 SIASVVD 70
SI ++ D
Sbjct: 60 SIHTITD 66
>ref|NP_057514.1| (NM_016430) Down syndrome critical region protein 5; Down
syndrome critical region protein C short form; Down
syndrome critical region protein C [Homo sapiens]
gb|AAF32289.1|AF216305_1 (AF216305) Down syndrome critical region protein C short form
[Homo sapiens]
dbj|BAA96873.1| (AB037164) DSCR5c [Homo sapiens]
Length = 108
Score = 32.5 bits (73), Expect = 3.7
Identities = 22/67 (32%), Positives = 39/67 (57%), Gaps = 6/67 (8%)
Query: 8 LVYVTWALLPVEF----GLHSYLPDKYFAVFVPFLVLVFAWFFAFLIYPAINLSMTVDVD 63
++Y+ WA +P + GL +Y P KY+AV +P +L+ A +++ IN+ T +D
Sbjct: 2 VLYLVWAFIPESWLNSLGL-TYWPQKYWAVALPVYLLI-AVVIGYVLLFGINMMSTSPLD 59
Query: 64 SIASVVD 70
SI ++ D
Sbjct: 60 SIHTITD 66
CPU time: 36.03 user secs. 1.65 sys. secs 37.68 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.327 0.140 0.441
Gapped
Lambda K H
0.270 0.0491 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83502506
Number of Sequences: 887402
Number of extensions: 3101918
Number of successful extensions: 12204
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 12194
Number of HSP's gapped (non-prelim): 23
length of query: 138
length of database: 277,845,442
effective HSP length: 49
effective length of query: 89
effective length of database: 234,362,744
effective search space: 20858284216
effective search space used: 20858284216
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (21.7 bits)
S2: 69 (31.2 bits)