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GPI Anchor Biosynthesis Report: T40030 (PIG-O family, Schizosaccharomyces pombe)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (918 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 5

Distribution of 61 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments: (bits) Value
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 1116 0.0
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 873 0.0
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 806 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 531 e-149
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 528 e-148
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 521 e-146
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 512 e-143
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 478 e-133
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 472 e-131
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 436 e-120
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 417 e-115
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 415 e-114
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 396 e-108
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 392 e-107
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 355 3e-96
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 338 2e-91
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 338 4e-91
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 309 2e-82
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 308 3e-82
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 305 2e-81
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 300 6e-80
ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus ... 292 1e-77
dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus] 292 1e-77
gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norve... 292 2e-77
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 288 3e-76
pir||A57080 cell surface antigen RB13-6 - rat >gi|806379|emb|CAA... 288 4e-76
ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phos... 286 1e-75
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 274 4e-72
dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located... 274 7e-72
pir||A39216 plasma cell membrane glycoprotein PC-1 - human >gi|7... 273 8e-72
ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phos... 271 4e-71
emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucle... 270 9e-71
ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phos... 267 4e-70
gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattu... 267 5e-70
gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphat... 266 1e-69
pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse 265 2e-69
ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyro... 265 2e-69
gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphata... 265 2e-69
sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodieste... 263 8e-69
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 259 1e-67
ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo ... 252 2e-65
pir||T33724 hypothetical protein - Zymomonas mobilis >gi|3089614... 241 5e-62
gb|AAD05192.1| (AC005587) phosphodiesterase I beta [Homo sapiens] 220 8e-56
ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campyl... 211 3e-53
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 196 2e-48
sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CH... 181 4e-44
Alignments
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score = 1116 bits (2857), Expect = 0.0
 Identities = 918/918 (100%), Positives = 918/918 (100%)

Query: 1   MEEKRVKCKKKLTSTIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCE 60
           MEEKRVKCKKKLTSTIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCE
Sbjct: 1   MEEKRVKCKKKLTSTIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCE 60

Query: 61  NPPADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLH 120
           NPPADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLH
Sbjct: 61  NPPADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLH 120

Query: 121 PENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQI 180
           PENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQI
Sbjct: 121 PENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQI 180

Query: 181 VLLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYL 240
           VLLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYL
Sbjct: 181 VLLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYL 240

Query: 241 GVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFD 300
           GVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFD
Sbjct: 241 GVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFD 300

Query: 301 EINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYY 360
           EINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYY
Sbjct: 301 EINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYY 360

Query: 361 GDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYF 420
           GDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYF
Sbjct: 361 GDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYF 420

Query: 421 KAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILA 480
           KAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILA
Sbjct: 421 KAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILA 480

Query: 481 NNELHSPFPAEFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSF 540
           NNELHSPFPAEFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSF
Sbjct: 481 NNELHSPFPAEFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSF 540

Query: 541 TVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREEQGA 600
           TVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREEQGA
Sbjct: 541 TVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAFILLQVISSYVTNCREEQGA 600

Query: 601 FCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELI 660
           FCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELI
Sbjct: 601 FCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELI 660

Query: 661 SSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVIER 720
           SSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVIER
Sbjct: 661 SSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVIER 720

Query: 721 SYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGLSH 780
           SYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGLSH
Sbjct: 721 SYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGLSH 780

Query: 781 FFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLFSFEPLSK 840
           FFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLFSFEPLSK
Sbjct: 781 FFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLFSFEPLSK 840

Query: 841 KNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVTHQLF 900
           KNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVTHQLF
Sbjct: 841 KNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVTHQLF 900

Query: 901 VLIQCFGSSVVKFPEDAE 918
           VLIQCFGSSVVKFPEDAE
Sbjct: 901 VLIQCFGSSVVKFPEDAE 918
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  873 bits (2234), Expect = 0.0
 Identities = 316/1014 (31%), Positives = 471/1014 (46%), Gaps = 149/1014 (14%)

Query: 3   EKRVKCKKKLTSTIGTWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENP 62
           ++++  K ++       K+    I    I I  F  +  FT GFLL R VL+  S     
Sbjct: 16  DEKIIYKSRIKKFQKNHKFYI--ILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNE- 72

Query: 63  PADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYND-----SNYYHNAFTTPYETS 117
                          P  F +AVI++IDALR+DF IP N+     +  YHN   + Y++ 
Sbjct: 73  -----------TSKLPPRFNKAVILVIDALRFDFAIPVNESHSNYNLNYHNNILSLYDSF 121

Query: 118 VLHPE-NSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSL 176
               + +S L +FIAD PTTT QRLKGLTTGSLPTFID GSNF GT I+EDN L Q    
Sbjct: 122 ASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLA 181

Query: 177 DKQIVLLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYI-KDANFDVL 235
           +K +   GDDTW  LFH +L+   S P  S NV DL  VDN V  Y  D++ +D  +DV+
Sbjct: 182 NKTVKFAGDDTWMALFHPFLS-NDSFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVM 240

Query: 236 IAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHG 295
           I H LG+DHVGH+ GPDH TMR+K  Q+D+ +  ++  +DD TLL+++GDHGMD+ GNHG
Sbjct: 241 IGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILKSIDDDTLLVILGDHGMDHTGNHG 300

Query: 296 GDSFDEINSVLWMYSKKPTFGYLKQPG---------KVLSANQVDLVPTLSLLLGNPIPY 346
           GDS DE+ S L++YSKKP    LK+              S  Q+DLV +L+LL+G PIP+
Sbjct: 301 GDSIDELESTLFLYSKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPF 360

Query: 347 GNLGTLIPEPFYYYGDEYLSKAQKINIGQLNRFFSEYDLDASDF---LSSSVHKNNNSYL 403
            NLG  I E      +        I+  QL +   +      +    L+ ++     +  
Sbjct: 361 NNLGWPIDEIARNDREWSQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSD 420

Query: 404 DQYF--LDFDYARDAFSYFKAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSA 461
            + F  L   Y +      + +WA+F  + +  G  LL      L LL+    +I  +  
Sbjct: 421 PEKFVKLGHKYQKVFLQTCEELWAKFDYYSIATGITLLATS---LVLLISITKLIPSIVV 477

Query: 462 NMAPSVMKCLPVCLILILANN---------ELHSPFPAEFY---------VLLPSFYILL 503
           N    V + +P  +I++L  N              F  +F+         +++  +  + 
Sbjct: 478 NQM--VPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIF 535

Query: 504 NSFNQKLMEYFKGFVKLDYFSI---FITFLHVCSFGSNSFTVWEDRLCHFLIITIGLV-- 558
           + +N   +    G    DY+S        +H   F SNSFT+WEDR+  FL+ T G++  
Sbjct: 536 DRYNFIWIAMRLGETLADYWSRIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTL 595

Query: 559 ---MFCKCFSEMS------------------PLFACSTY----------------SALAF 581
              +F       +                  P  A S Y                  + F
Sbjct: 596 YEFVFLPKRQSTTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGGYHSAVLIIF 655

Query: 582 ILLQVISSYVTNCREEQGAFCVSTYISTPDNSLRTLIVLALMALSSIIL----------- 630
             L   +S +T CREEQG +C+ T+ +  +NS  +  VL L  L   IL           
Sbjct: 656 TRL---ASMITICREEQGEYCIPTF-NNQNNS--SWWVLGLCFLMIFILPACITGYYNLT 709

Query: 631 -------PLILQLHLRRVLGLSLKLYHLS-------ILYFFELIS-SIFWIA-HHVFAND 674
                  P+ + + L+ +LGL+   + L+       ++    L   +IF      + A  
Sbjct: 710 SSYQAAAPIWINVFLKGILGLNFVYWSLTSLENNSAVIAIPFLRDVTIFKFTLARIIAGF 769

Query: 675 ALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRSKFAKINVIERSYFVFALLYSFLSF 734
           +L+      ++  L     I    V   +  +L    +  I   E    V  +L S L F
Sbjct: 770 SLIASNVGWLMGPLCIKLNIHNTDVKSHEATIL---GYTNIYGSEFFLLVINVLISILLF 826

Query: 735 LQRPLGHLSLFSC---FLQILLLIQLKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAAIS 791
             +PL  LS F      L IL +I L + + ++      + LGLL   HFFTTG+QA I 
Sbjct: 827 -NKPLAQLSYFLMCNQLLSILEIIDLLKLKENI---IGPIALGLLSYQHFFTTGHQATIP 882

Query: 792 SLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLF---SFEPLSKKNRFLINL 848
           S+ W+  F+ S+       + I + L+T G  IL  +S+ L    S  P   K + L+  
Sbjct: 883 SVQWDIGFMLSEKVTF-PFTQIAIILNTFGPHILVSLSVALLTLWSQPPDVLKPQTLLGR 941

Query: 849 FRFSFSFIL-YNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVTHQLFV 901
              +   +L YN ++  S+  +   FRRHLMVWK+F PRF+ + + L+  QL V
Sbjct: 942 IVSNCGILLTYNTILCLSSFIWVTHFRRHLMVWKIFCPRFIFASLSLIVTQLVV 995
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  806 bits (2060), Expect = 0.0
 Identities = 240/950 (25%), Positives = 408/950 (42%), Gaps = 158/950 (16%)

Query: 26  IFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAV 85
           I   ++ I+    L  F +GFLL+R  +   S C +  A          CW  + ++R +
Sbjct: 5   IRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQP-----GQTCWMKQQYQRVI 59

Query: 86  IVIIDALRYDFLIPYNDSN------YYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQ 139
           ++++DALRYDFLIP +++       +Y+       E  ++   N  +   +AD PTTT Q
Sbjct: 60  LILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEK-LVKSGNVSIGTLLADPPTTTLQ 118

Query: 140 RLKGLTTGSLPTFIDLGSNFAGT-NIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNE 198
           RLK LTTG+LPTFID G NF+    I ED+ + Q   L K + LLGDDTW  LF +  ++
Sbjct: 119 RLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSK 178

Query: 199 TLSQPAFSFNVPDLHGVDNKVNQYVF------------------DYIKDANFDVLIAHYL 240
           T +  +F  N  DL+ VD+K+ + +F                  D + ++N  ++IAH+L
Sbjct: 179 TAAYDSFDIN--DLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFL 236

Query: 241 GVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFD 300
           GVDH GH+ GP HP M D L +MDR + + ++ +          DHGM + G+HGG+S +
Sbjct: 237 GVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DHGMTSTGDHGGESEN 289

Query: 301 EINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFY-- 358
           EI + + ++SKK      ++P      +Q+D+VPT+SLL+G PIP+ NLGT+I + F   
Sbjct: 290 EIRAGILVHSKKHQIILPERP-----IHQIDIVPTISLLMGLPIPFSNLGTVITQLFTRD 344

Query: 359 -----------YYGDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYF 407
                       + D     A+     +       + +  S+ +     + +     Q  
Sbjct: 345 LWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDSNTMEE---QLDTMSRIQTL 401

Query: 408 LDFDYARDAFSYFKAIWAEFSLFPMIIGFLLLIIGGFNLALLMQDKSVIFRMSANMAPSV 467
           L     R +++ F   +    +F ++   + LI        +M  + +I+R    +    
Sbjct: 402 L-----RVSWTQFDDAYINAGIFSLVEAIMFLITNE-----VMSLEWIIYRTGCGL---- 447

Query: 468 MKCLPVCLILILANNELHSPFPAEFYVLLPSFYILLNSFN------QKLMEYFKGFVKLD 521
                  L   L  ++  S   A   +L+      L+S         ++    K  +   
Sbjct: 448 -------LQAALLTDKTDSDGSARTLLLMTLAVSCLSSIISMCHKALQIRISIKSMLSAK 500

Query: 522 YFSIFITFLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCKCFSEMS-----PL------ 570
                +  +H  S  SNS+ V+E ++  + + ++  ++F +     +     P       
Sbjct: 501 VIGPILVIIHSISLFSNSYVVYEAQVVRYFLQSLVTLVFLEKLRSTALRPRKPFKLNFLW 560

Query: 571 -FACSTYSALAFILLQV---ISSYVTNCREEQGAFCVSTYISTPDNSLR--TLIVLALMA 624
            F     + + F L+ V          CREE+   C + Y S    SL     +V  L A
Sbjct: 561 KFVNQDQNLIIFTLIMVGLRSEPIFHRCREEEVG-CDTYYPSRQAGSLTRDAQVVRLLFA 619

Query: 625 LSSIILPLILQLHLRRVLGLSLKLYHLSILYFFELISSIFWIAHHVFANDALLEKQYHHV 684
           L                   SL + +LS+  ++ L  +   I  +         K+    
Sbjct: 620 LG------------------SLAVANLSVFKYYGLRDTKSQIESN--------SKRSSET 653

Query: 685 LYSLANTYVICILGVLIWQFFLLSRSKFAKINVIERSYFVFALLYSFLS----------- 733
           +  L+ T  + I  +++   F       ++ N+   S  V +L+ + L+           
Sbjct: 654 IRILSATSWLHIAIIVLHSVFASLTHDVSRANLSAHSLSVISLICAVLAWREGNSAICAH 713

Query: 734 FLQRPL------GHLSLFSCFLQILLLIQLKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQ 787
           FL  P+      G +     F+ + +LI        V   F + T+ LL    F+  G+ 
Sbjct: 714 FLLMPVYILFGDGLIPAIIIFIAVSVLI-----AEFVSREFIASTIALLIPLGFYHLGHS 768

Query: 788 AAISSLDWNFAFIHSKSAE-NQAISAIFMFLHTVGAPILTCISIPLFSFEPLSKKNRFLI 846
             ISS+ WN AF+        + + A+F+  H   + I    SI + S E  S +     
Sbjct: 769 PVISSIPWNAAFVGIPGGTALRVLPALFVLFHLNFSAI---SSIFVISSESESSQKMSAP 825

Query: 847 NLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVT 896
           N        ++   + +T T   +   RRHLMVWK+FAP+F+   IL + 
Sbjct: 826 NTAWTLTETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIV 875
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  531 bits (1355), Expect = e-149
 Identities = 93/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +   + + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFVSIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LGV
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGV 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
 Score =  531 bits (1355), Expect = e-149
 Identities = 93/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +   + + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFVSIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LGV
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGV 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
 Score =  531 bits (1355), Expect = e-149
 Identities = 93/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +   + + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFVSIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LGV
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGV 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  528 bits (1346), Expect = e-148
 Identities = 92/617 (14%), Positives = 174/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVI-----IHEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
 Score =  528 bits (1346), Expect = e-148
 Identities = 92/617 (14%), Positives = 174/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVI-----IHEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
 Score =  528 bits (1346), Expect = e-148
 Identities = 92/617 (14%), Positives = 174/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVI-----IHEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  521 bits (1328), Expect = e-146
 Identities = 93/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +   + + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFVSIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LGV
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGV 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
 Score =  521 bits (1328), Expect = e-146
 Identities = 93/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +   + + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFVSIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LGV
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGV 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLIIGG-F 444
                  + +     + ++  +   +  S  +          S +       L I     
Sbjct: 391 KLLSDSQQLDILRKARSYIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVG 450

Query: 445 NLALLMQDKSVIFRMSANMAPS------------VMKCLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+               +   +   +++         P+    
Sbjct: 451 FVGWMSYTSLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +  +   Q L+E    F +  + +  + F     + V SF        
Sbjct: 511 YCLLPVPIWYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL++F
Sbjct: 566 -------YMLTAGLIVF 575
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score =  512 bits (1306), Expect = e-143
 Identities = 94/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFTLGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
             R V+ + D LR D L   +++      F                       PT +   
Sbjct: 43  ARRLVLFVADGLRADALYELDENGNSRAPFIRNIIM-----HEGSWGISHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYI------------KDANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +  + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  + L  +     +                +  +  K L  NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L  +      +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVDYLN---NTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLI-IGGF 444
                  + N     + ++      +  S  K          S +     F L + +   
Sbjct: 391 KLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIG 450

Query: 445 NLALLMQDKSVIFRMSANMAPSVMK------------CLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+   V K             + + +++         P+    
Sbjct: 451 FVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +      Q L+     +    +    + F     + V SF        
Sbjct: 511 YGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL  F
Sbjct: 566 -------YMLTAGLTAF 575
 Score =  512 bits (1306), Expect = e-143
 Identities = 94/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFTLGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
             R V+ + D LR D L   +++      F                       PT +   
Sbjct: 43  ARRLVLFVADGLRADALYELDENGNSRAPFIRNIIM-----HEGSWGISHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYI------------KDANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +  + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  + L  +     +                +  +  K L  NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L  +      +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVDYLN---NTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLI-IGGF 444
                  + N     + ++      +  S  K          S +     F L + +   
Sbjct: 391 KLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIG 450

Query: 445 NLALLMQDKSVIFRMSANMAPSVMK------------CLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+   V K             + + +++         P+    
Sbjct: 451 FVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +      Q L+     +    +    + F     + V SF        
Sbjct: 511 YGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL  F
Sbjct: 566 -------YMLTAGLTAF 575
 Score =  512 bits (1306), Expect = e-143
 Identities = 94/617 (15%), Positives = 173/617 (27%), Gaps = 122/617 (19%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFTLGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
             R V+ + D LR D L   +++      F                       PT +   
Sbjct: 43  ARRLVLFVADGLRADALYELDENGNSRAPFIRNIIM-----HEGSWGISHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYI------------KDANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAKREDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +  + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  + L  +     +                +  +  K L  NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS------ 393
            P P  ++G L  +      +  L KA+ +  N  Q+   F        +          
Sbjct: 334 VPFPLNSVGILPVDYLN---NTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPF 390

Query: 394 ----SVHKNNNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLI-IGGF 444
                  + N     + ++      +  S  K          S +     F L + +   
Sbjct: 391 KLLSDSKQFNILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIG 450

Query: 445 NLALLMQDKSVIFRMSANMAPSVMK------------CLPVCLILILANNELHSPFPAEF 492
            +  +     +I +  +N+   V K             + + +++         P+    
Sbjct: 451 FVGWISYASLLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYV 510

Query: 493 YVLLP----SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVW 543
           Y LLP       +      Q L+     +    +    + F     + V SF        
Sbjct: 511 YGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYR----- 565

Query: 544 EDRLCHFLIITIGLVMF 560
                   ++T GL  F
Sbjct: 566 -------YMLTAGLTAF 575
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  478 bits (1219), Expect = e-133
 Identities = 97/635 (15%), Positives = 192/635 (29%), Gaps = 104/635 (16%)

Query: 33  ISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAVIVIIDAL 92
                G+       L    +  +T +          +            +R V++I D L
Sbjct: 45  WLVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS-------EPPAKRLVLLISDGL 97

Query: 93  RYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTF 152
           R D     ++   Y   F                    A  PT +      +  G     
Sbjct: 98  RADKFFEPDEEGKYRAPFLRNII-----KNQGRWGVSHARPPTESRPGHVAIIAGFYEDP 152

Query: 153 IDLGSNFAGTNIDEDNLLLQ----WKSLDKQIVLLG-----DDTWDVLFHDYLNETLSQP 203
             +   +    ++ D++  Q    +      I+ +        TW+  +     +  +  
Sbjct: 153 SAVTKGWKANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNS-YPHEYEDFATDA 211

Query: 204 AFSFNVPDLHGVDNKVNQ-YVFDYIK---DANFDVLIAHYLGVDHVGHRLGPDHPTMRDK 259
           +F  +       +  +N+ +    +K     +  V+  H LG D  GH   P      + 
Sbjct: 212 SF-LDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNN 270

Query: 260 LNQMDRCVKEMMDLL-----DDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKPT 314
           +  +D+  + +  LL     D+ T  I   DHGM +KG+HG       ++ L  +     
Sbjct: 271 VKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQ 330

Query: 315 FG----------------------------YLKQPGKVLSANQVDLVPTLSLLLGNPIPY 346
           +                             +  +  + +  NQ D+ P +S LLG P P 
Sbjct: 331 YPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPV 390

Query: 347 GNLGTLIPEPFYYYGDEYLSKAQKINIGQLNRFFSEYDLDASDFL-----SSSVHKNNNS 401
            ++G L          E +          LN+   +  + +S+ L        VH + + 
Sbjct: 391 NSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPLVHHSFSL 450

Query: 402 YLDQYFLDFDYARDAFSYFKAI----------WAEFSLFPMIIGFLLLIIGGFNLALLMQ 451
                 +       A      +          +  +    ++    L   G   + L + 
Sbjct: 451 SQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGW-MIVLALH 509

Query: 452 DKSVIFRMSANMAPS--VMKCLPVCLILIL---ANNELHSPFPAEFYVLLPSFY--ILLN 504
                  +S +++    +   +  CL++ +    N   HSP     Y+ +  F    + +
Sbjct: 510 VLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFS 569

Query: 505 SFNQKL-MEYFKGFVKLDYFSIFITF---------LHVCSFGSNSFTVWEDRLCHFLIIT 554
            +     +  +    + DYF   +           L V SF       W      F +I 
Sbjct: 570 EYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTW------FFLIA 623

Query: 555 IG----LVMFCKCFSEMSPLFAC-STYSALAFILL 584
                 L+ F   +    P+F C S +    F L+
Sbjct: 624 GVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLM 658
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  472 bits (1203), Expect = e-131
 Identities = 160/422 (37%), Positives = 223/422 (51%), Gaps = 31/422 (7%)

Query: 24  ACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSG----CWAPK 79
             +F A +    + G+  FT GFLL R  L   S C+ PP        S G    CW   
Sbjct: 6   VLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMAS 65

Query: 80  IFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQ 139
            F R V+V+IDALR+DF  P +                 + P ++ L +   D PTTT Q
Sbjct: 66  RFSRVVLVLIDALRFDFAQPQHSHRILE-----------IQPHHARLYRSQVDPPTTTMQ 114

Query: 140 RLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNET 199
           RLK LTTGSLPTFID GSNFA   I EDNL+ Q  S  +++V +GDDTW  LF    ++ 
Sbjct: 115 RLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKA 174

Query: 200 LSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDK 259
              P+F+  V DL  VDN + ++++  +    +DVLIAH+LGVDH GH+ GP HP M  K
Sbjct: 175 FFFPSFN--VRDLDTVDNGILEHLYPTMDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKK 232

Query: 260 LNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKPTFGYLK 319
           L+QMD+ ++ +++ L++ TLL+V GDHGM   G+HGGDS  E+++ L++YS    F    
Sbjct: 233 LSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPS-T 291

Query: 320 QPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDEY-------LSKAQKIN 372
            P +     QV LVPTL+LLLG PIP+GN+G ++ E F    D          + A  +N
Sbjct: 292 PPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLN 351

Query: 373 IGQLNRFFSEYDLDASDFLSSSVHKNNNSY-----LDQYFLD-FDYARDAFSYFKAIWAE 426
             Q++RF   Y     D  +  +H+  N +       Q+ L     A        A   +
Sbjct: 352 AQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEATLPTVIAELQQ 411

Query: 427 FS 428
           F 
Sbjct: 412 FL 413
 Score =  232 bits (586), Expect = 2e-59
 Identities = 45/298 (15%), Positives = 79/298 (26%), Gaps = 65/298 (21%)

Query: 631 PLILQLHLRRVLGLSLKLYHLSILYFFELISSIFWIAHHVFANDALLEKQYHHVLYSLAN 690
           PL +  +       S+    +           +   A  +     LL  Q   +L+ LA 
Sbjct: 590 PLTVAAYQLG----SVYSAAMVTALTLLAFPLLLLHAERISLVFLLLFLQSFLLLHLLAA 645

Query: 691 TYVICILGVLIWQFFLLSRSKFAKINVIERSYFVFALLYSFLSFLQRPLGH-----LSLF 745
              +   G  +    L   S  +         F   LL  FLS  + P+ H       + 
Sbjct: 646 GIPVTTPGKYLSSDSLKDNSDVS----SAPLVFKEVLLLMFLSLTEGPMPHTTRKVFLVS 701

Query: 746 SCFLQILLLIQ----------------LKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAA 789
           S    I   I                  K   P            L+    F++TG+Q  
Sbjct: 702 SLLPAIAKQIDPSCWFPGFMERRDKESSKTPCPFTVPWQAVSAWALMATQTFYSTGHQPV 761

Query: 790 ISSLDWNFAFIHSKSAENQA--ISAIFM--------FLHTVGAPILTCISIPL------- 832
             ++ W+ AF+           + A+ +         L  VG P+L              
Sbjct: 762 FPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRK 821

Query: 833 ----FSFEPLSKKN-------------RFLINLFRFSFSF--ILYNLLISTSTVFFAG 871
                  E  ++               R     F  +     + Y  ++ +    +A 
Sbjct: 822 RQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGSYLRLWAS 879
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  436 bits (1110), Expect = e-120
 Identities = 82/602 (13%), Positives = 166/602 (26%), Gaps = 106/602 (17%)

Query: 20  KYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPK 79
             +   + F +  + + + +                + L                     
Sbjct: 8   TLLAVGVLFHLFYLWSIFDI-------------YFISPLVHGMSPY--------QSTPTP 46

Query: 80  IFERAVIVIIDALRYDFLI-PYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTS 138
             +R  +++ D LR D               F  P+  S++   N+         PT + 
Sbjct: 47  PAKRLFLIVGDGLRADTTFDKVTHPVSGKTEFLAPFIRSLVM-NNATYGISHTRMPTESR 105

Query: 139 QRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQ----WKSLDKQIVLLGDDTWDVLFHD 194
                +  G       +   +    ++ D+   Q    +      I+ +  D        
Sbjct: 106 PGHVAMIAGFYEDVSAVTKGWKSNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASD---P 162

Query: 195 YLNETLSQPA-FSFNVPDLHGVDNKVNQYVF------------DYIKDANFDVLIAHYLG 241
              +T      F         +D  V +++             DY    + +V   H LG
Sbjct: 163 NKVDTWMYDHTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLG 222

Query: 242 VDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL-----DDSTLLIVMGDHGMDNKGNHGG 296
            D  GH   P      D +  +D  +  ++D +     DD T  I   DHGM   G+HG 
Sbjct: 223 CDTAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGD 282

Query: 297 DSFDEINSVLWMYSKKPTFG--------------YLKQPGKVLSANQVDLVPTLSLLLGN 342
              +   + L  +                     +     K     Q D+   +S L+G 
Sbjct: 283 GHPNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGV 342

Query: 343 PIPYGNLGTLIPEPFYYYGDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSV------- 395
             P  ++G L               A   N         +Y +   + + S         
Sbjct: 343 NYPKNSVGELPIAYIDGKE-SDKLAALYNNA---RSILEQYLVKQDEVIDSQFFYKEYFK 398

Query: 396 ----HKNNNSYLDQYFLDFDY------ARDAFSYFKAIWA----------EFSLFPMIIG 435
                 ++     +  +           ++A +  + +             ++   +   
Sbjct: 399 FVEKSHSHYLEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTI 458

Query: 436 FLLLIIGGFNLALLMQDKSVIFRMSANMAPSVM----KCLPVCLILILANNELHSPFPAE 491
                +G    + ++  KS I     +   +          + ++L       HSPF   
Sbjct: 459 VTFGFVGWIFFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFY 518

Query: 492 FYVLLP-SFYILLNSFNQKLMEYFKGFVKLDY-FSIFITFLHVCSFGSNSFTVWEDRLCH 549
            Y+L P  F+  + +    L    K F K    +   +  + + S       V+E  +  
Sbjct: 519 MYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIIS-------VYEGIVYG 571

Query: 550 FL 551
           F 
Sbjct: 572 FF 573
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  417 bits (1061), Expect = e-115
 Identities = 84/597 (14%), Positives = 180/597 (30%), Gaps = 104/597 (17%)

Query: 20  KYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPK 79
           + +   I F ++ + + + +                T L            ++    A  
Sbjct: 4   RLLLLGILFHVVFLKSIFDI-------------YFVTPLIHGMK-----QYSAGEAPAK- 44

Query: 80  IFERAVIVIIDALRYD-FLIPYNDSNYY-HNAFTTPYETSVLHPENSYLTQFIADAPTTT 137
              R  +++ D LR D  L P+++        +  P+  S++   N          PT +
Sbjct: 45  ---RLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQ-NNGTFGVSHTRVPTES 100

Query: 138 SQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLN 197
                 L  G       +   +    ++ D++  Q     +     G +    +F +  +
Sbjct: 101 RPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQ----SRHTYSFGSEDILPMFSEGAS 156

Query: 198 ETLSQPAFSFNVPDLHGVDNKV--NQYVFDYIK----------------DANFDVLIAHY 239
           +      F ++        N +  +++VFD +                   +  V   H 
Sbjct: 157 DPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHL 216

Query: 240 LGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGN 293
           LG+D +GH   PD     + +  +D  ++E++D +      D ++  +   DHGM + G+
Sbjct: 217 LGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGS 276

Query: 294 HGGDSFDEINSVLWMYSKKPT--------------FGYLKQPGKVLSANQVDLVPTLSLL 339
           HG  + D   + +  +                     +     K +   Q D+   +S L
Sbjct: 277 HGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYL 336

Query: 340 LGNPIPYGNLGTLIPEPFYYYGDEYLSKAQ-------------KINIGQLNRFFSEYDLD 386
           +G   P  ++G +  +            A                +  Q + FF  Y   
Sbjct: 337 VGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPL 396

Query: 387 ASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYF----------KAIWAEFSLFPMIIGF 436
            +     +   N+     +          A  +                 +    +    
Sbjct: 397 RNYTEVQASFYNSVIADIES----GEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIV 452

Query: 437 LLLIIGG--FNLALLMQDKSVIFRMS---ANMAPSVMKCLPVCLILILANNELHSPFPAE 491
               +    + +  +               ++   V   +P  LI I    +   PF   
Sbjct: 453 FFGYLSWIGYVICFVFSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYG 512

Query: 492 FYVLLPSFYILLNSFNQKLMEYFKGFVKLDY----FSIF-ITFLHVCSFGSNSFTVW 543
           + +    F  L++S        FK F+ +      FS+  I F+ +C      F V+
Sbjct: 513 YALFPTIFLQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVY 569
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  415 bits (1056), Expect = e-114
 Identities = 69/414 (16%), Positives = 118/414 (27%), Gaps = 74/414 (17%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLG 341
               E  +    +     F                +  +  K    NQ D+ P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 342 NPIPYGNLGTLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS 393
            P P  ++G L         +  L KA+ +  N  Q+   F        +    
Sbjct: 334 VPFPLNSVGILPVGYLN---NTGLFKAESMFTNAVQILEQFKVKMTQKKEATLP 384
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  396 bits (1008), Expect = e-108
 Identities = 80/488 (16%), Positives = 145/488 (29%), Gaps = 96/488 (19%)

Query: 150 PTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYLNETLSQPA- 204
                +   +    ++ D+L       W      I+ +               T S  A 
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMF----AKGASGDHVYTYSYDAK 56

Query: 205 -FSFNVPDLHGVDNKVNQYVFDYI------------KDANFDVLIAHYLGVDHVGHRLGP 251
              F   D   +D  V   V D+              +    V   H LG+D  GH   P
Sbjct: 57  REDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRP 116

Query: 252 DHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGGDSFDEINSV 305
                +  + ++D  VKE++ +       D  T  I   DHGM + G+HG     E  + 
Sbjct: 117 SSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTP 176

Query: 306 LWMYSKKPTFG---------------YLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLG 350
           L  +     +                +  +  K L  NQ D+ P ++ L+G P P  ++G
Sbjct: 177 LVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVG 236

Query: 351 TLIPEPFYYYGDEYLSKAQKI--NIGQLNRFFSEYDLDASDFLSS----------SVHKN 398
            L  +      +  L KA+ +  N  Q+   F        +                 + 
Sbjct: 237 ILPVDYLN---NTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQF 293

Query: 399 NNSYLDQYFLDFDYARDAFSYFKA----IWAEFSLFPMIIGFLLLI-IGGFNLALLMQDK 453
           N     + ++      +  S  K          S +     F L + +    +  +    
Sbjct: 294 NILRKARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYAS 353

Query: 454 SVIFRMSANMAPSVMK------------CLPVCLILILANNELHSPFPAEFYVLLP---- 497
            +I +  +N+   V K             + + +++         P+    Y LLP    
Sbjct: 354 LLIIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIW 413

Query: 498 SFYILLNSFNQKLMEYFKGFVKLDYFSIFITF-----LHVCSFGSNSFTVWEDRLCHFLI 552
              +      Q L+     +    +    + F     + V SF                +
Sbjct: 414 YAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYR------------YM 461

Query: 553 ITIGLVMF 560
           +T GL  F
Sbjct: 462 LTAGLTAF 469
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  392 bits (999), Expect = e-107
 Identities = 153/454 (33%), Positives = 224/454 (48%), Gaps = 51/454 (11%)

Query: 18  TWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWK------- 70
              Y+   I+ A  LIS+  G+  F+ GFLL R    +TS C     +            
Sbjct: 2   NLTYLFVLIWLAF-LISS--GVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVV 58

Query: 71  -------NSSGCWAPKIFERAVIVIIDALRYDF-LIPYN--DSNYYHNAFTTPYETSVLH 120
                  N+S         + +++++DAL+Y+F L   N  D   Y N      E    +
Sbjct: 59  NEIFKDVNASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQN 118

Query: 121 PENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQI 180
           P+++ L +F AD PTTT QRLKGLTTGSLPTFID+GSNFA   I+EDN++ Q    D  +
Sbjct: 119 PDHARLMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPV 178

Query: 181 VLLGDDTWDVLFHDYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYL 240
           V LGD TW  L+      + S P+F     DL  VDN++ +++   ++  ++ VL+AH+L
Sbjct: 179 VFLGDSTWTDLYPHRFKRSYSYPSFDIF--DLDSVDNEILKHLPKELESKDWQVLVAHFL 236

Query: 241 GVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHGGDSFD 300
           GVDH GH+ GP H  M  KL +M+  ++ ++  +D+ T L+VMGDHGM   G+HGGD+ D
Sbjct: 237 GVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAMDNDTTLLVMGDHGMTASGDHGGDTDD 296

Query: 301 EINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYY 360
           E N++L+ YSK+  F             Q+DLVPTL+ +LG PIPY NLG +        
Sbjct: 297 ETNALLFAYSKQHRFYGNDSGSDSEMLQQIDLVPTLATILGVPIPYSNLGLVNFNIVPDL 356

Query: 361 GDEYLSKAQKI------NIGQLNRFFSEYDLDAS-DFLSSSVHKNNNSYLDQYFLDFDYA 413
              +L+K Q +      N  Q+ R+F +Y L+    F    +      ++    L     
Sbjct: 357 RVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRTFNVEQMDHLETEFI---LLTHRVQ 413

Query: 414 -------------------RDAFSYFKAIWAEFS 428
                              RD     + IW  F 
Sbjct: 414 TVYNEVAFKSFVRDLNTNLRDILGTCREIWVRFD 447
 Score = 85.2 bits (209), Expect = 4e-15
 Identities = 15/49 (30%), Positives = 22/49 (44%)

Query: 849  FRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSGILLVTH 897
            F+ +  F +   L     +       RHLMVWK+FAPRF+   +     
Sbjct: 998  FKLATQFFMLQGLKIFCAMLACTIHCRHLMVWKIFAPRFIYEALATFVS 1046
 Score = 46.6 bits (110), Expect = 0.002
 Identities = 36/160 (22%), Positives = 56/160 (34%), Gaps = 18/160 (11%)

Query: 709 RSKFAKINVIERSYFVFAL-----LYSFLSFLQRPLGHLSLFSC------FLQILLLIQL 757
           RS    +  +   Y    +     L   +  L  P   + L  C       L +  +++ 
Sbjct: 796 RSHIPVVYGLATVYSSIVIAFGVFLALVMIVLLEPRASIGLVVCVAVGAILLSVHSILRY 855

Query: 758 KQWQPS---VGHNF-FSVTLGLLGLSHFFTTGNQAAISSLDWNFAFIHSKSAENQA--IS 811
           +        V   F   V   LL    FF T +Q  +S ++W  AF+   +   Q+  +S
Sbjct: 856 RTATSFESCVQPTFTALVGWFLLAHFCFFATSHQTTLSQIEWRAAFVGRTTGIGQSNLVS 915

Query: 812 AIFMFLHTVGAPILTCISIPLFSFEPLSKKNRFLINLFRF 851
              + L+T   PI       L S E  S    F  NL R 
Sbjct: 916 GALVILNTFCGPIFFFCMYSLLSTETFSLFALF-PNLIRS 954
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  355 bits (902), Expect = 3e-96
 Identities = 84/380 (22%), Positives = 142/380 (37%), Gaps = 59/380 (15%)

Query: 18  TWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWA 77
           +WK++ A I   ++LI + +              V   + L    P     + NS    A
Sbjct: 2   SWKFLIASITVHLVLIYSIFD-------------VYYTSPLVHGIPPQ---FINSQEAPA 45

Query: 78  PKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTT 137
            +IF    I+  D LRYD    Y D + Y          S+++          +  PT +
Sbjct: 46  KRIF----IISADGLRYDTFNKYPDKSPY--------LHSIMNERKGIYGLSRSHIPTES 93

Query: 138 SQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQ----WKSLDKQIVLLGDDTWDVLFH 193
                 +  G       +   +    +  D++  +    W      IV L DD       
Sbjct: 94  RPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDL-----P 148

Query: 194 DYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLG 241
           +  + + S     F   D   +D  V ++  ++++                 +   H LG
Sbjct: 149 NAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLG 208

Query: 242 VDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD-----STLLIVMGDHGMDNKGNHGG 296
           +D  GH   P      D +  +D  ++++  L+D       T  +   DHGM + G+HG 
Sbjct: 209 IDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGA 268

Query: 297 DSFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEP 356
            S DE+ +    +        +KQ G  L  NQ+DL P +S L+G PIP  ++G L  + 
Sbjct: 269 GSDDEVLTPFVAWGAG-----VKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQM 323

Query: 357 FYYYGDEYLSKAQKINIGQL 376
               G  Y  KA + N  Q+
Sbjct: 324 MNSKGSSYEFKAIEANFKQV 343
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  338 bits (859), Expect = 2e-91
 Identities = 52/322 (16%), Positives = 88/322 (27%), Gaps = 54/322 (16%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVESDSLFNERKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFGYL 318
               E  +    +     F   
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQN 295
 Score =  338 bits (859), Expect = 2e-91
 Identities = 52/322 (16%), Positives = 88/322 (27%), Gaps = 54/322 (16%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +    +    +  ++ + +                + L                   P  
Sbjct: 4   FFALGLLIHFVFFASIFDI-------------YFTSPLVHGMTPQFT--------PLPPP 42

Query: 81  FERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQR 140
            +R V+ + D LR D L   ++       F                       PT +   
Sbjct: 43  AKRLVLFVADGLRADTLYELDEDGNSRAPFIRNVIM-----HEGSWGVSHTRVPTESRPG 97

Query: 141 LKGLTTGSLPTFIDLGSNFAGTNIDEDNLLL----QWKSLDKQIVLLGDDTWDVLFHDYL 196
              L  G       +   +    ++ D+L       W      I+ +             
Sbjct: 98  HVALIAGFYEDVSAVAKGWKENPVESDSLFNERKYTWSWGSPDILPMF----AKGASGDH 153

Query: 197 NETLSQPA--FSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLGV 242
             T S  A    F   D   +D  V   V D+              +    V   H LG+
Sbjct: 154 VYTYSYDAQREDFGAHDATKLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGI 213

Query: 243 DHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGG 296
           D  GH   P     +D + ++D  VKE++ +       D  T  I   DHGM + G+HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 297 DSFDEINSVLWMYSKKPTFGYL 318
               E  +    +     F   
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQN 295
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  338 bits (858), Expect = 4e-91
 Identities = 85/383 (22%), Positives = 142/383 (36%), Gaps = 59/383 (15%)

Query: 18  TWKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWA 77
           +WK++ A I   ++LI + +              V   + L    P     + NS    A
Sbjct: 2   SWKFLIASITVHLVLIYSIFD-------------VYYTSPLVHGIPPQ---FINSQEAPA 45

Query: 78  PKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTT 137
            +IF    I+  D LRYD    Y D + Y          S+++          +  PT +
Sbjct: 46  KRIF----IISADGLRYDTFNKYPDKSPY--------LHSIMNERKGIYGLSRSHIPTES 93

Query: 138 SQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQ----WKSLDKQIVLLGDDTWDVLFH 193
                 +  G       +   +    +  D++  +    W      IV L DD       
Sbjct: 94  RPGHVAIFAGITEDISAVAKGWKKNPVQFDSVFNRSSYSWMWGSPDIVNLFDDL-----P 148

Query: 194 DYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIK------------DANFDVLIAHYLG 241
           +  + + S     F   D   +D  V ++  ++++                 +   H LG
Sbjct: 149 NAESFSYSADEEDFASKDASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLG 208

Query: 242 VDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD-----STLLIVMGDHGMDNKGNHGG 296
           +D  GH   P      D +  +D  ++++  L+D       T  +   DHGM + G+HG 
Sbjct: 209 IDTNGHGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGA 268

Query: 297 DSFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEP 356
            S DE+ +    +        +KQ G  L  NQ+DL P +S L+G PIP  ++G L  + 
Sbjct: 269 GSDDEVLTPFVAWGAG-----VKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQM 323

Query: 357 FYYYGDEYLSKAQKINIGQLNRF 379
               G  Y  KA + N  QL   
Sbjct: 324 MNSKGSSYEFKAIEANFKQLKEQ 346
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  309 bits (784), Expect = 2e-82
 Identities = 50/321 (15%), Positives = 99/321 (30%), Gaps = 40/321 (12%)

Query: 48  LRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYH 107
           L   ++   ++  N       +               +++  D  R+ +       N   
Sbjct: 21  LTVLIVLSVAVTANGSDSPSSYVRRPQPPKKLNKPVVLLISCDGFRFGYQFKTETPN--- 77

Query: 108 NAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDED 167
                   +     +       I   PT T      + TG  P    +  N     +  +
Sbjct: 78  ---IDLLISRGTEAKTG----LIPVFPTMTFPNHYSIATGLYPASHGIIMNKFTDPVSGE 130

Query: 168 NL---LLQWKSLDKQIV----LLGDDTWDVLFHDYLNETLSQPA--------FSFNVPDL 212
                L     L + +       G       +        S           ++ +VP  
Sbjct: 131 LFNRNLNPKWWLGEPLWVTAVNQGLMAATYFWPGADVHKGSWNCPKGFCKAPYNVSVPLE 190

Query: 213 HGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMD 272
             VD  +N   FD  +    D +  ++   D  GH  GPD P + + ++++D+ +  ++ 
Sbjct: 191 ERVDTILN--YFDLPEREIPDFMALYFDEPDIQGHEYGPDDPRVTEAVSKVDKMIGRIIM 248

Query: 273 LLD-----DSTLLIVMGDHGMDNKGN----HGGDSFDEINSVL-WMYSKKPTFGYLKQPG 322
            L+         +I++GDHGM    +    +  D  D I     W+    P      + G
Sbjct: 249 GLEKRKVFSDVHVILLGDHGMVTNCDKKVIYIDDLADWIKIPADWIQDYSPVLAMNPRWG 308

Query: 323 KVLSAN---QVDLVPTLSLLL 340
           K +        +LV  ++  L
Sbjct: 309 KDVKNPGQKNAELVRKMNEAL 329
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  308 bits (782), Expect = 3e-82
 Identities = 61/345 (17%), Positives = 113/345 (32%), Gaps = 49/345 (14%)

Query: 26  IFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAV 85
           I F + LI     +                  L   P    R W         K+ +  V
Sbjct: 8   ISFKLSLI-FLLNIFIVATIAAAAAVNAGTKGLDSRPSKTRRPW------PFKKLNKPVV 60

Query: 86  I-VIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGL 144
           + +  D  R+ +    +  N           +     ++      I   PT T      +
Sbjct: 61  LMISCDGFRFGYQFKTDTPN------IDLLISGGTEAKHG----LIPVFPTMTFPNHYSI 110

Query: 145 TTGSLPTFIDLGSNFAGTNID---EDNLLLQWKSLDKQIV----LLGDDTWDVLFHDYLN 197
            TG  P +  +  N     +     +  L     L + +       G       +     
Sbjct: 111 ATGLYPAYHGIIMNKFTDPVTGEVFNKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPGSEV 170

Query: 198 ETLSQ-------PAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLG 250
              S        P F+ +VP    VD+ ++   FD+++D   D+L+ ++   D  GH  G
Sbjct: 171 LKSSWTCPEGYCPHFNLSVPLEERVDSVLSH--FDHLEDEVPDLLMLYFDEPDQSGHNYG 228

Query: 251 PDHPTMRDKLNQMDRCVKEMMDLLDDS-----TLLIVMGDHGMDNKG------NHGGDSF 299
           PD P +   ++++D+ +  ++  L          +I++GDHGM           +  D  
Sbjct: 229 PDDPRVTTAVSRVDKMIGRVIKGLKQREIFDEVHVILLGDHGMVTNCECNEKAIYIDDLA 288

Query: 300 DEINSV-LWMYSKKPTFGYLKQPGKVLSA---NQVDLVPTLSLLL 340
           D I     W+ +  P      Q GK +        ++V  ++  L
Sbjct: 289 DWIKIPAAWIQAYSPVLAINPQWGKDVENQSEKNAEVVAKMNEAL 333
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  305 bits (775), Expect = 2e-81
 Identities = 61/345 (17%), Positives = 114/345 (32%), Gaps = 48/345 (13%)

Query: 26  IFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAV 85
           +F +  L S+F                     L   P    R W         K+ +  V
Sbjct: 2   LFLSNFLSSSFLIFFIVATIAAAAAVNAGTKGLDSRPSKTRRPW------PFKKLNKPVV 55

Query: 86  I-VIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGL 144
           + +  D  R+ +    +  N           +     ++      I   PT T      +
Sbjct: 56  LMISCDGFRFGYQFKTDTPN------IDLLISGGTEAKHG----LIPVFPTMTFPNHYSI 105

Query: 145 TTGSLPTFIDLGSNFAGTNID---EDNLLLQWKSLDKQIV----LLGDDTWDVLFHDYLN 197
            TG  P +  +  N     +     +  L     L + +       G       +     
Sbjct: 106 ATGLYPAYHGIIMNKFTDPVTGEVFNKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPSSEV 165

Query: 198 ETLSQ-------PAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLG 250
              S        P F+ +VP    VD+ ++   FD+++D   D+L+ ++   D  GH  G
Sbjct: 166 LKSSWTCPEGYCPHFNLSVPLEERVDSVLSH--FDHLEDEVPDLLMLYFDEPDQSGHNYG 223

Query: 251 PDHPTMRDKLNQMDRCVKEMMDLLDDS-----TLLIVMGDHGMDNKG------NHGGDSF 299
           PD P +   ++++D+ +  ++  L          +I++GDHGM           +  D  
Sbjct: 224 PDDPRVTTAVSRVDKMIGRVIKGLKQREIFDEVHVILLGDHGMVTNCECNEKAIYIDDLA 283

Query: 300 DEINSV-LWMYSKKPTFGYLKQPGKVLSA---NQVDLVPTLSLLL 340
           D I     W+ +  P      Q GK +        ++V  ++  L
Sbjct: 284 DWIKIPAAWIQAYSPVLAINPQWGKDVENQSEKNAEVVAKMNEAL 328
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  300 bits (762), Expect = 6e-80
 Identities = 50/338 (14%), Positives = 99/338 (28%), Gaps = 44/338 (13%)

Query: 24  ACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFER 83
             I       +      SF   FL   +     S         R                
Sbjct: 43  LLISLLSTTFTAVIAAVSFAFLFLSATSAAAGESKTIKITTTARSLT-------KLTHPI 95

Query: 84  AVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKG 143
            +++  D  R+ +       N             +++   S     I   PT T      
Sbjct: 96  VILISSDGFRFGYQFKAPTPN----------IHRLINNGTSAELGLIPVFPTLTFPNHYS 145

Query: 144 LTTGSLPTFIDLGSNFAGTNIDEDNL----LLQWKSLDKQIVLL----GDDTWDVLFHDY 195
           + TG  P    + +N+    I  D            L + +       G       +   
Sbjct: 146 IVTGLYPPHHGIINNYFVDPITGDKFSMASHEPKWWLGEPLWETVAKHGKKAATYFWPGS 205

Query: 196 LNETLSQP-------AFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHR 248
                           ++ ++P    VD  ++   FD   +     +  ++   DH GH+
Sbjct: 206 EVIKPDWDCPSNYCIHYNGSIPFEERVDTVIS--YFDLPINEIPVFMTLYFEDPDHQGHQ 263

Query: 249 LGPDHPTMRDKLNQMDRCVKEMMDLLD-----DSTLLIVMGDHGMDNKGNHGGDSFDEIN 303
           +GPD P +   +  +D+ +  ++  L+     +   + ++GDHGM    +      D++ 
Sbjct: 264 VGPDDPEITQAVINIDKMIGRLIKGLEKRGVFEDVNIFMVGDHGMVGTCDKKLIFLDDLE 323

Query: 304 SVL-WMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLL 340
               W+ S  P       P         ++V  ++  L
Sbjct: 324 IPSNWVQSYTPLLAISPPPEFS----PAEIVAKMNSGL 357
>ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus norvegicus]
 gb|AAB61535.1| (U78787) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  292 bits (742), Expect = 1e-77
 Identities = 57/310 (18%), Positives = 90/310 (28%), Gaps = 40/310 (12%)

Query: 56  TSLCENPPADVREW-KNSSGCWAPKIF--ERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
            ++C+     V E   +S     P+ F     ++  +D  R ++L  ++      N   T
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKT 190

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
               S             A  PT T      + TG  P    +  N         N    
Sbjct: 191 CGLHSKY---------MRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLS 241

Query: 170 ----LLQWKSLDKQIVL----LGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I L     G       +                 +S +VP    + 
Sbjct: 242 SVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRI- 300

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             + Q++ D  K         +    D  GH+ GP    +   L  +D     +M+ L  
Sbjct: 301 ATLLQWL-DLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQ 359

Query: 277 S-----TLLIVMGDHGMDNKGNHGG----DSFDEINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   +IV+ DHGMD           D F EIN         P       P    + 
Sbjct: 360 RNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEIN-FYMYQGPAPRIRTRNIPQDFFTF 418

Query: 328 NQVDLVPTLS 337
           N  ++V  LS
Sbjct: 419 NSEEIVRDLS 428
>dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus]
          Length = 876

 Score =  292 bits (742), Expect = 1e-77
 Identities = 57/310 (18%), Positives = 90/310 (28%), Gaps = 40/310 (12%)

Query: 56  TSLCENPPADVREW-KNSSGCWAPKIF--ERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
            ++C+     V E   +S     P+ F     ++  +D  R ++L  ++      N   T
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKT 190

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
               S             A  PT T      + TG  P    +  N         N    
Sbjct: 191 CGLHSKY---------MRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLS 241

Query: 170 ----LLQWKSLDKQIVL----LGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I L     G       +                 +S +VP    + 
Sbjct: 242 SVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRI- 300

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             + Q++ D  K         +    D  GH+ GP    +   L  +D     +M+ L  
Sbjct: 301 ATLLQWL-DLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQ 359

Query: 277 S-----TLLIVMGDHGMDNKGNHGG----DSFDEINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   +IV+ DHGMD           D F EIN         P       P    + 
Sbjct: 360 RNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEIN-FYMYQGPAPRIRTRNIPQDFFTF 418

Query: 328 NQVDLVPTLS 337
           N  ++V  LS
Sbjct: 419 NSEEIVRDLS 428
>gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  292 bits (741), Expect = 2e-77
 Identities = 57/310 (18%), Positives = 90/310 (28%), Gaps = 40/310 (12%)

Query: 56  TSLCENPPADVREW-KNSSGCWAPKIF--ERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
            ++C+     V E   +S     P+ F     ++  +D  R ++L  ++      N   T
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKT 190

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
               S             A  PT T      + TG  P    +  N         N    
Sbjct: 191 CGLHSKY---------MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLS 241

Query: 170 ----LLQWKSLDKQIVL----LGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I L     G       +                 +S +VP    + 
Sbjct: 242 SVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRI- 300

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             + Q++ D  K         +    D  GH+ GP    +   L  +D     +M+ L  
Sbjct: 301 ATLLQWL-DLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQ 359

Query: 277 S-----TLLIVMGDHGMDNKGNHGG----DSFDEINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   +IV+ DHGMD           D F EIN         P       P    + 
Sbjct: 360 RNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEIN-FYMYQGPAPRIRTRNIPQDFFTF 418

Query: 328 NQVDLVPTLS 337
           N  ++V  LS
Sbjct: 419 NSEEIVRDLS 428
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  288 bits (731), Expect = 3e-76
 Identities = 61/379 (16%), Positives = 119/379 (31%), Gaps = 58/379 (15%)

Query: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80
           +I   +   +  I+           F  ++ VL+   + ++P      +  S      K+
Sbjct: 51  FIFTSLLL-VTCIALSAASAFAFLFFSSQKPVLSLNQISKSP-----AFDRSVARPLKKL 104

Query: 81  FERAV-IVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQ 139
            +  V ++  D  R+ +                P    ++       T  I   PT T  
Sbjct: 105 DKPVVLLISSDGFRFGYQFKT----------KLPSIHRLIANGTEAETGLIPVFPTLTFP 154

Query: 140 RLKGLTTGSLPTFIDLGSNFAGTNIDEDNLL-----LQWKSLDKQIV----LLGDDTWDV 190
               + TG  P +  + +N      +  N+           L + +       G      
Sbjct: 155 NHYSIVTGLYPAYHGIINNHFVDP-ETGNVFTMASHEPEWWLGEPLWETVVNQGLKAATY 213

Query: 191 LFHDYLNETLSQPA-------FSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVD 243
            +        S          ++ +VP    VD  ++   FD   +     +  ++   D
Sbjct: 214 FWPGSEVHKGSWNCPQGLCQNYNGSVPFDDRVDTILS--YFDLPSNEIPSFMTLYFEDPD 271

Query: 244 HVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLD-----DSTLLIVMGDHGMDNKGNHG--- 295
           H GH++GPD P + + +  +DR +  ++D L+     +   +I++GDHGM    +     
Sbjct: 272 HQGHQVGPDDPQITEAVVNIDRLIGRLIDGLEKRGIFEDVTMIMVGDHGMVGTCDKKLVV 331

Query: 296 -GDSFDEINSV-LWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLI 353
             D    I     W+    P        G        D+V  ++  L       + G + 
Sbjct: 332 LDDLAPWIKIPSSWVQYYTPLLAIQPPSGHDA----ADIVAKINEGL-------SSGKVE 380

Query: 354 PE-PFYYYGDEYLSKAQKI 371
                  Y  E L      
Sbjct: 381 NGKYLKVYLKEDLPSRLHY 399
>pir||A57080 cell surface antigen RB13-6 - rat
 emb|CAA88029.1| (Z47987) RB13-6 antigen [Rattus norvegicus]
          Length = 875

 Score =  288 bits (730), Expect = 4e-76
 Identities = 57/310 (18%), Positives = 90/310 (28%), Gaps = 40/310 (12%)

Query: 56  TSLCENPPADVREW-KNSSGCWAPKIF--ERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
            ++C+     V E   +S     P+ F     ++  +D  R ++L  ++      N   T
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKT 190

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
               S             A  PT T      + TG  P    +  N         N    
Sbjct: 191 CGLHSKY---------MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLS 241

Query: 170 ----LLQWKSLDKQIVL----LGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I L     G       +                 +S +VP    + 
Sbjct: 242 SVEKSNPAWWSGQPIWLTAMYQGLKAASYYWLGSDVAVNGSFPNIYRNYSNSVPYESRI- 300

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             + Q++ D  K         +    D  GH+ GP    +   L  +D     +M+ L  
Sbjct: 301 ATLLQWL-DLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQ 359

Query: 277 S-----TLLIVMGDHGMDNKGNHGG----DSFDEINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   +IV+ DHGMD           D F EIN         P       P    + 
Sbjct: 360 RNLHNCVNIIVLADHGMDQTSCDRVEYMTDYFPEIN-FYMYQGPAPRIRTRNIPQDFFTF 418

Query: 328 NQVDLVPTLS 337
           N  ++V  LS
Sbjct: 419 NSEEIVRDLS 428
>ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phosphodiesterase 3;
           phosphodiesterase I/nucleotide pyrophosphatase 3;
           phosphodiesterase-I beta; gp130RB13-6; bovine intestinal
           phosphodiesterase [Homo sapiens]
 gb|AAC51813.1| (AF005632) phosphodiesterase I/nucleotide pyrophosphatase beta
           [Homo sapiens]
          Length = 875

 Score =  286 bits (726), Expect = 1e-75
 Identities = 52/310 (16%), Positives = 90/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW-KNSSGCWAPKIF--ERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
            S+C+   + + E    +     P+ F     ++  +D  R ++L  ++      N   T
Sbjct: 130 KSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKT 189

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLL-- 170
               S             A  PT T      + TG  P    +  N         N    
Sbjct: 190 CGIHSKY---------MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLS 240

Query: 171 -----LQWKSLDKQIVL----LGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + + L     G       +                 ++ +VP    + 
Sbjct: 241 SKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERIS 300

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             + +++ D  K         ++   D  GH  GP    +   L  +D     +M+ L  
Sbjct: 301 T-LLKWL-DLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQ 358

Query: 277 S-----TLLIVMGDHGMDNKGNHG----GDSFDEINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   +I++ DHGMD    +      D F  IN         P       P    S 
Sbjct: 359 RNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFSF 418

Query: 328 NQVDLVPTLS 337
           N  ++V  LS
Sbjct: 419 NSEEIVRNLS 428
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  274 bits (695), Expect = 4e-72
 Identities = 54/339 (15%), Positives = 109/339 (31%), Gaps = 52/339 (15%)

Query: 28  FAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAVIV 87
             ++L +      S+         +L +T L     +       ++           +++
Sbjct: 47  LHLLLTAALAVATSYLL------LILPRTPL-----SAAPAPAAAARAQVKLEKPVVILI 95

Query: 88  IIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTG 147
             D  R+ +                 +   ++    S  T  +   PT T      + TG
Sbjct: 96  SSDGFRFGYQHKAATP----------HIHRLIGNGTSAATGLVPIFPTLTFPNHYSIATG 145

Query: 148 SLPTFIDLGSNFAGTNIDEDNL----LLQWKSLDKQIV----LLGDDTWDVLFHDYLNET 199
             P+   + +N+    I  D            L + +       G       +     + 
Sbjct: 146 LYPSSHGIINNYFPDPISGDYFTMSSHEPKWWLGEPLWVTAADQGIQAATYFWPGSEVKK 205

Query: 200 LSQP-------AFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPD 252
            S          ++ +VP    VD  +    FD   D     L  ++   DH GH++GPD
Sbjct: 206 GSWDCPDKYCRHYNGSVPFEERVDAIL--GYFDLPSDEMPQFLTLYFEDPDHQGHQVGPD 263

Query: 253 HPTMRDKLNQMDRCVKEMMDLLD-----DSTLLIVMGDHGMDNKGNHG----GDSFDEIN 303
            P + + + ++D  +  ++  L+     +   +I++GDHGM    +       +    I 
Sbjct: 264 DPAITEAVVRIDEMIGRLIAGLEERGVFEDVNVILVGDHGMVGTCDKKLVFLDELAPWIK 323

Query: 304 SVL-WMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLG 341
               W+ S  P           +S    D+V  ++  LG
Sbjct: 324 LEEDWVLSMTPLLAIRPP--DDMSLP--DVVAKMNEGLG 358
>dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located at nucleotides
           17-19, followed by a second ATG codon 52 codons
           downstream. And the second ATG codon is potential
           initiation point for translation of NPPase. [Homo
           sapiens]
          Length = 930

 Score =  274 bits (694), Expect = 7e-72
 Identities = 49/310 (15%), Positives = 88/310 (27%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW---KNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C+   + V E     N   C A       ++  +D  R ++L  +       +    
Sbjct: 186 SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK 245

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 246 CGT---YTKN------MRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 296

Query: 170 ----LLQWKSLDKQIV----LLGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I       G  +    +                 ++ +VP    + 
Sbjct: 297 SKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERIL 356

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V Q++    KD        +    D  GH  GP    +   L ++D  V  +MD L +
Sbjct: 357 A-VLQWL-QLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE 414

Query: 277 ST-----LLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++ ++  +Y           P K  S 
Sbjct: 415 LNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSF 474

Query: 328 NQVDLVPTLS 337
           N   +   LS
Sbjct: 475 NYEGIARNLS 484
>pir||A39216 plasma cell membrane glycoprotein PC-1 - human
 gb|AAF36094.1| (AF110304) PDNP1 [Homo sapiens]
 emb|CAC39442.1| (AJ242020) plasma cell membrane glycoprotein [Homo sapiens]
          Length = 925

 Score =  273 bits (693), Expect = 8e-72
 Identities = 49/310 (15%), Positives = 88/310 (27%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW---KNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C+   + V E     N   C A       ++  +D  R ++L  +       +    
Sbjct: 181 SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK 240

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 241 CGT---YTKN------MRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 291

Query: 170 ----LLQWKSLDKQIV----LLGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I       G  +    +                 ++ +VP    + 
Sbjct: 292 SKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERIL 351

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V Q++    KD        +    D  GH  GP    +   L ++D  V  +MD L +
Sbjct: 352 A-VLQWL-QLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE 409

Query: 277 ST-----LLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++ ++  +Y           P K  S 
Sbjct: 410 LNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSF 469

Query: 328 NQVDLVPTLS 337
           N   +   LS
Sbjct: 470 NYEGIARNLS 479
>ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phosphodiesterase 1;
           phosphodiesterase I/nucleotide pyrophosphatase 1
           (homologous to mouse Ly-41 antigen); plasma-cell
           membrane glycoprotein [Homo sapiens]
 sp|P22413|PC1_HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (PLASMA-CELL
           MEMBRANE GLYCOPROTEIN PC-1) [INCLUDES: ALKALINE
           PHOSPHODIESTERASE I ; NUCLEOTIDE PYROPHOSPHATASE
           (NPPASE)]
 gb|AAA63237.1| (M57736) plasma cell membrane glycoprotein PC-1 [Homo sapiens]
 dbj|BAA02054.1| (D12485) NPPase [Homo sapiens]
          Length = 873

 Score =  271 bits (687), Expect = 4e-71
 Identities = 49/310 (15%), Positives = 88/310 (27%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW---KNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C+   + V E     N   C A       ++  +D  R ++L  +       +    
Sbjct: 129 SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK 188

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 189 CGT---YTKN------MRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 239

Query: 170 ----LLQWKSLDKQIV----LLGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I       G  +    +                 ++ +VP    + 
Sbjct: 240 SKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERIL 299

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V Q++    KD        +    D  GH  GP    +   L ++D  V  +MD L +
Sbjct: 300 A-VLQWL-QLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE 357

Query: 277 ST-----LLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++ ++  +Y           P K  S 
Sbjct: 358 LNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSF 417

Query: 328 NQVDLVPTLS 337
           N   +   LS
Sbjct: 418 NYEGIARNLS 427
>emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucleotide
           pyrophosphatase 1 (homologous to mouse Ly-41 antigen)
           (PC1, NPPS)) [Homo sapiens]
          Length = 845

 Score =  270 bits (684), Expect = 9e-71
 Identities = 49/310 (15%), Positives = 88/310 (27%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW---KNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C+   + V E     N   C A       ++  +D  R ++L  +       +    
Sbjct: 101 SSVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKK 160

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 161 CGT---YTKN------MRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 211

Query: 170 ----LLQWKSLDKQIV----LLGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGVD 216
                       + I       G  +    +                 ++ +VP    + 
Sbjct: 212 SKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERIL 271

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V Q++    KD        +    D  GH  GP    +   L ++D  V  +MD L +
Sbjct: 272 A-VLQWL-QLPKDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE 329

Query: 277 ST-----LLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++ ++  +Y           P K  S 
Sbjct: 330 LNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSF 389

Query: 328 NQVDLVPTLS 337
           N   +   LS
Sbjct: 390 NYEGIARNLS 399
>ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Rattus norvegicus]
 gb|AAK69654.1|AF340186_1 (AF340186) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  267 bits (678), Expect = 4e-70
 Identities = 48/310 (15%), Positives = 90/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW---KNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C+   + V E     ++  C A       ++  +D  R ++L  +       +    
Sbjct: 163 SSVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKN 222

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 223 CGT---YTKN------MRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 273

Query: 170 ----LLQWKSLDKQIVLLGDD----TWDVLFHDYLNE-----TLSQPAFSFNVPDLHGVD 216
                       + I +  +     +    +     E           ++ +VP    + 
Sbjct: 274 SKEKFNPLWYKGQPIWVTANHQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERIL 333

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V +++              +    D  GH  GP    +   L ++D  V  +MD L D
Sbjct: 334 A-VLEWL-QLPSYERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKD 391

Query: 277 S-----TLLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++N+V  +Y         + P    S 
Sbjct: 392 LGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYSF 451

Query: 328 NQVDLVPTLS 337
           N   L   LS
Sbjct: 452 NYEALAKNLS 461
>gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattus norvegicus]
          Length = 906

 Score =  267 bits (677), Expect = 5e-70
 Identities = 48/310 (15%), Positives = 90/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW---KNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C+   + V E     ++  C A       ++  +D  R ++L  +       +    
Sbjct: 163 SSVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKN 222

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 223 CGT---YTKN------MRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 273

Query: 170 ----LLQWKSLDKQIVLLGDD----TWDVLFHDYLNE-----TLSQPAFSFNVPDLHGVD 216
                       + I +  +     +    +     E           ++ +VP    + 
Sbjct: 274 SKEKFNPLWYKGQPIWVTANHQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERIL 333

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V +++              +    D  GH  GP    +   L ++D  V  +MD L D
Sbjct: 334 A-VLEWL-QLPSYERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKD 391

Query: 277 S-----TLLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++N+V  +Y         + P    S 
Sbjct: 392 LGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLNPPEVPETYYSF 451

Query: 328 NQVDLVPTLS 337
           N   L   LS
Sbjct: 452 NYEALAKNLS 461
>gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  266 bits (675), Expect = 1e-69
 Identities = 48/310 (15%), Positives = 90/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVREW---KNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C+   + V E     ++  C A       ++  +D  R ++L  +       +    
Sbjct: 163 SSVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKN 222

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 223 CGT---YTKN------MRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 273

Query: 170 ----LLQWKSLDKQIVLLGDD----TWDVLFHDYLNE-----TLSQPAFSFNVPDLHGVD 216
                       + I +  +     +    +     E           ++ +VP    + 
Sbjct: 274 SKEKFNPLWYKGQPIWVTANHQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERIL 333

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V +++              +    D  GH  GP    +   L ++D  V  +MD L D
Sbjct: 334 A-VLEWL-QLPSYERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKD 391

Query: 277 S-----TLLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++N+V  +Y         + P    S 
Sbjct: 392 LGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYSF 451

Query: 328 NQVDLVPTLS 337
           N   L   LS
Sbjct: 452 NYEALTKNLS 461
>pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse
          Length = 905

 Score =  265 bits (672), Expect = 2e-69
 Identities = 49/310 (15%), Positives = 91/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVR---EWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C++  + V    E  ++  C A       ++  +D  R ++L  +       +    
Sbjct: 163 SSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKN 222

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 223 CGT---YTKN------MRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 273

Query: 170 ----LLQWKSLDKQIVLLGDD----TWDVLFHDYLNE-----TLSQPAFSFNVPDLHGVD 216
                       + I +  +     +    +     E           ++ +VP    + 
Sbjct: 274 SKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERIL 333

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V +++              +    D  GH  GP    +   L ++DR V  +MD L D
Sbjct: 334 A-VLEWL-QLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD 391

Query: 277 S-----TLLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++N+V  +Y           P    S 
Sbjct: 392 LGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSF 451

Query: 328 NQVDLVPTLS 337
           N   L   LS
Sbjct: 452 NYEALAKNLS 461
>ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyrophosphatase 1; 1
           ectonucleotide pyrophosphatase/phosphodiesterase 1 [Mus
           musculus]
 gb|AAA39893.2| (J02700) ecto-nucleotide pyrophosphatase/phosphodiesterase-1 [Mus
           musculus domesticus]
          Length = 905

 Score =  265 bits (672), Expect = 2e-69
 Identities = 49/310 (15%), Positives = 91/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVR---EWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C++  + V    E  ++  C A       ++  +D  R ++L  +       +    
Sbjct: 163 SSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKN 222

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 223 CGT---YTKN------MRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 273

Query: 170 ----LLQWKSLDKQIVLLGDD----TWDVLFHDYLNE-----TLSQPAFSFNVPDLHGVD 216
                       + I +  +     +    +     E           ++ +VP    + 
Sbjct: 274 SKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERIL 333

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V +++              +    D  GH  GP    +   L ++DR V  +MD L D
Sbjct: 334 A-VLEWL-QLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD 391

Query: 277 S-----TLLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++N+V  +Y           P    S 
Sbjct: 392 LGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSF 451

Query: 328 NQVDLVPTLS 337
           N   L   LS
Sbjct: 452 NYEALAKNLS 461
>gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphatase/phosphodiesterase 1
           allotype b [Mus musculus]
          Length = 906

 Score =  265 bits (672), Expect = 2e-69
 Identities = 49/310 (15%), Positives = 91/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVR---EWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C++  + V    E  ++  C A       ++  +D  R ++L  +       +    
Sbjct: 163 SSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKN 222

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 223 CGT---YTKN------MRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 273

Query: 170 ----LLQWKSLDKQIVLLGDD----TWDVLFHDYLNE-----TLSQPAFSFNVPDLHGVD 216
                       + I +  +     +    +     E           ++ +VP    + 
Sbjct: 274 SKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERIL 333

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V +++              +    D  GH  GP    +   L ++DR V  +MD L D
Sbjct: 334 A-VLEWL-QLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD 391

Query: 277 S-----TLLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++N+V  +Y           P    S 
Sbjct: 392 LGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSF 451

Query: 328 NQVDLVPTLS 337
           N   L   LS
Sbjct: 452 NYEALAKNLS 461
>sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Plasma-cell
           membrane glycoprotein PC-1) [Includes: Alkaline
           phosphodiesterase I ; Nucleotide pyrophosphatase
           (NPPASE)]
          Length = 871

 Score =  263 bits (668), Expect = 8e-69
 Identities = 49/310 (15%), Positives = 91/310 (28%), Gaps = 39/310 (12%)

Query: 56  TSLCENPPADVR---EWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTT 112
           +S+C++  + V    E  ++  C A       ++  +D  R ++L  +       +    
Sbjct: 129 SSVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKN 188

Query: 113 PYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNL--- 169
                                PT T      + TG  P    +  N         +    
Sbjct: 189 CGT---YTKN------MRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLK 239

Query: 170 ----LLQWKSLDKQIVLLGDD----TWDVLFHDYLNE-----TLSQPAFSFNVPDLHGVD 216
                       + I +  +     +    +     E           ++ +VP    + 
Sbjct: 240 SKEKFNPLWYKGQPIWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERIL 299

Query: 217 NKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDD 276
             V +++              +    D  GH  GP    +   L ++DR V  +MD L D
Sbjct: 300 A-VLEWL-QLPSHERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD 357

Query: 277 S-----TLLIVMGDHGMDNKGNHGGDSFD----EINSVLWMYSKKPTFGYLKQPGKVLSA 327
                   LI++ DHGM+          +    ++N+V  +Y           P    S 
Sbjct: 358 LGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSF 417

Query: 328 NQVDLVPTLS 337
           N   L   LS
Sbjct: 418 NYEALAKNLS 427
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  259 bits (657), Expect = 1e-67
 Identities = 79/215 (36%), Positives = 115/215 (52%), Gaps = 14/215 (6%)

Query: 227 IKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDH 286
           +    +DVLIAH+LGVDH GH+ GP HP M  KL+QMD+ ++ +++ L++ TLL+V GDH
Sbjct: 1   MDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDH 60

Query: 287 GMDNKGNHGGDSFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPY 346
           GM   G+HGGDS  E+++ L++YS    F     P +     QV LVPTL+LLLG PIP+
Sbjct: 61  GMTTNGDHGGDSELEVSAALFLYSPTAVFPS-TPPEEPEVIPQVSLVPTLALLLGLPIPF 119

Query: 347 GNLGTLIPEPFYYYGDEY-------LSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNN 399
           GN+G ++ E F    D          + A  +N  Q++RF   Y     D  +  +H+  
Sbjct: 120 GNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQ 179

Query: 400 NSY-----LDQYFLD-FDYARDAFSYFKAIWAEFS 428
           N +       Q+ L     A        A   +F 
Sbjct: 180 NLFSKASADYQWLLQSPKGAEATLPTVIAELQQFL 214
 Score =  205 bits (519), Expect = 2e-51
 Identities = 41/204 (20%), Positives = 67/204 (32%), Gaps = 40/204 (19%)

Query: 740 GHLSLFSCFLQILLL-IQLKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAAISSLDWNFA 798
              SL    L +L   I +    P            L+    F++TG+Q    ++ W+ A
Sbjct: 226 ARFSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAA 285

Query: 799 FIHSKSAENQA--ISAIFM--------FLHTVGAPILTCISIPL-----------FSFEP 837
           F+           + A+ +         L  VG P+L                     E 
Sbjct: 286 FVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEA 345

Query: 838 LSKKN-------------RFLINLFRFSFSFI----LYNLLISTSTV-FFAGFFRRHLMV 879
            ++               R     F  +   +    L+ L I        A   RRHLMV
Sbjct: 346 DARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMV 405

Query: 880 WKVFAPRFMLSGILLVTHQLFVLI 903
           WKVFAP+F+   +  +   + +L+
Sbjct: 406 WKVFAPKFIFEAVGFIVSSVGLLL 429
>ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH01030.1|AAH01030 (BC001030) Similar to phosphatidylinositol glycan, class O [Homo
           sapiens]
          Length = 454

 Score =  252 bits (639), Expect = 2e-65
 Identities = 75/215 (34%), Positives = 111/215 (50%), Gaps = 14/215 (6%)

Query: 227 IKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDH 286
           +    ++V   H LGVDH GH+ GP HP M  KL+QMD+ ++ +++ L++ TLL+V GDH
Sbjct: 1   MDSGEWEVSNQHVLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDH 60

Query: 287 GMDNKGNHGGDSFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPY 346
           GM   G+HGGDS  E+++ L++YS    F     P +     QV LVPTL+LLLG PIP+
Sbjct: 61  GMTTNGDHGGDSELEVSAALFLYSPTAVFPS-TPPEEPEVIPQVSLVPTLALLLGLPIPF 119

Query: 347 GNLGTLIPEPFYYYGDEY-------LSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNN 399
           GN+G ++ E F    D          + A  +N  Q++RF   Y     D  +  +H+  
Sbjct: 120 GNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQ 179

Query: 400 NSY-----LDQYFLD-FDYARDAFSYFKAIWAEFS 428
           N +       Q+ L     A        A   +F 
Sbjct: 180 NLFSKASADYQWLLQSPKGAEATLPTVIAELQQFL 214
 Score =  207 bits (522), Expect = 9e-52
 Identities = 41/204 (20%), Positives = 67/204 (32%), Gaps = 40/204 (19%)

Query: 740 GHLSLFSCFLQILLL-IQLKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAAISSLDWNFA 798
              SL    L +L   I +    P            L+    F++TG+Q    ++ W+ A
Sbjct: 226 ARFSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTGHQPVFPAIHWHAA 285

Query: 799 FIHSKSAENQA--ISAIFM--------FLHTVGAPILTCISIPL-----------FSFEP 837
           F+           + A+ +         L  VG P+L                     E 
Sbjct: 286 FVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQGLRKRQQPPGNEA 345

Query: 838 LSKKN-------------RFLINLFRFSFSFI----LYNLLISTSTV-FFAGFFRRHLMV 879
            ++               R     F  +   +    L+ L I        A   RRHLMV
Sbjct: 346 DARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILACALAASILRRHLMV 405

Query: 880 WKVFAPRFMLSGILLVTHQLFVLI 903
           WKVFAP+F+   +  +   + +L+
Sbjct: 406 WKVFAPKFIFEAVGFIVSSVGLLL 429
>pir||T33724 hypothetical protein - Zymomonas mobilis
 gb|AAC70363.1| (AF086791) unknown [Zymomonas mobilis]
          Length = 429

 Score =  241 bits (610), Expect = 5e-62
 Identities = 49/305 (16%), Positives = 95/305 (31%), Gaps = 42/305 (13%)

Query: 59  CENPPADVREWKNSSGCWAPKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSV 118
           C        +   ++     +     +++ ID  R D++      N    A    Y    
Sbjct: 25  CAGLSVVHSDAIAATAHVTAQSKTPLILISIDGFRADYIKRGLTPNLVSLAENGSYAK-- 82

Query: 119 LHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDL-GSNFAGTNIDEDNLLL------ 171
                          P+ T      L TG  P    + G+N    +I  D+         
Sbjct: 83  ---------VMHPSFPSITFPNHYTLVTGLYPDHHGIVGNNMDDAHITPDSHFKMSDHQA 133

Query: 172 ----QWKSLDKQIVLLGDD----TWDVLFHDYL-----NETLSQPAFSFNVPDLHGVDNK 218
               +W    + + +  +     +  + +                 F  +VP    VD  
Sbjct: 134 ATDRRWWDEGEPLWVTAEKQGVVSATMFWPGSEADIEGVRPEMWRQFDSHVPFSERVDQV 193

Query: 219 VNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDS- 277
            +   +   K      +  ++  VDH GH  GPD   + D L ++D+ + +++  L    
Sbjct: 194 FSWLAY--PKKKRPQFITLYFENVDHAGHLYGPDSQEVNDNLVKIDQTIGQLVQGLKQRG 251

Query: 278 --TLLIVMGDHGMDNKGNHGGDSFDEINSVLWMY--SKKPTFGYLKQPGKVLSANQVDLV 333
               L+++ DHGM    +    + ++I      +  +     G     G  L     DL 
Sbjct: 252 IKANLVIVSDHGMAATSSDRVVALNKILDPSLYHVVTGGAYAGIEPSSGHSLK----DLE 307

Query: 334 PTLSL 338
           P  + 
Sbjct: 308 PLFAS 312
>gb|AAD05192.1| (AC005587) phosphodiesterase I beta [Homo sapiens]
          Length = 687

 Score =  220 bits (556), Expect = 8e-56
 Identities = 43/251 (17%), Positives = 68/251 (26%), Gaps = 36/251 (14%)

Query: 112 TPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLL- 170
           T    S             A  PT T      + TG  P    +  N         N   
Sbjct: 1   TCGIHSKY---------MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSL 51

Query: 171 ------LQWKSLDKQIVL----LGDDTWDVLFHDYLN-----ETLSQPAFSFNVPDLHGV 215
                        + + L     G       +                 ++ +VP    +
Sbjct: 52  SSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERI 111

Query: 216 DNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLD 275
              + +++ D  K         ++   D  GH  GP    +   L  +D     +M+ L 
Sbjct: 112 ST-LLKWL-DLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLK 169

Query: 276 DS-----TLLIVMGDHGMDNKGNHG----GDSFDEINSVLWMYSKKPTFGYLKQPGKVLS 326
                    +I++ DHGMD    +      D F  IN         P       P    S
Sbjct: 170 QRNLHNCVNIILLADHGMDQTYCNKMEYMTDYFPRINFFYMYEGPAPRIRAHNIPHDFFS 229

Query: 327 ANQVDLVPTLS 337
            N  ++V  LS
Sbjct: 230 FNSEEIVRNLS 240
>ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campylobacter jejuni]
 pir||D81344 hypothetical protein Cj0729 [imported] - Campylobacter jejuni
           (strain NCTC 11168)
 emb|CAB73003.1| (AL139076) hypothetical protein Cj0729 [Campylobacter jejuni]
          Length = 269

 Score =  211 bits (534), Expect = 3e-53
 Identities = 50/277 (18%), Positives = 102/277 (36%), Gaps = 41/277 (14%)

Query: 82  ERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRL 141
            +A++V++D L           N    +    Y  ++             + P+ +    
Sbjct: 3   SKAILVVLDGL-----------NCKSASINMGYLNALCKENLGKFYSLECELPSMSRPLY 51

Query: 142 KGLTTGSLPTFIDLGSN---FAGTNIDEDNLLLQ-WKSLDKQIVLLGDDTWDVLFHDYLN 197
           + L TG  P    + +N   F+      D    Q  K+       + +      F   L+
Sbjct: 52  ECLLTGVKPVLSGIINNKLSFSKQTSIFDLCKEQGLKAGGAAYHWVFELYNKKEFIPSLH 111

Query: 198 E-------TLSQPAFSFNVPDLHGVDNKVNQYVF---DYIKDA-NFDVLIAHYLGVDHVG 246
                   TL    F +        D+ ++ ++F   +++++  N D  + H + +D  G
Sbjct: 112 RHIEDENLTLPYGHFYYE-------DDYLDSHLFADGEHLRNKYNLDFTLIHSMNIDDAG 164

Query: 247 HRLGPDHPTMRDKLNQMDRCVKEMM-DLLDDSTLLIVMGDHGMDNKGNHGGDSFDEINSV 305
           H+ G       +K  ++D  + E +   L+    +I+  DHGM    +HGG S DEI   
Sbjct: 165 HKFGSHSIEYANKTKKVDILISEYLPTWLEQGINVIITSDHGMTEGKSHGGLSEDEILVP 224

Query: 306 LWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGN 342
            + +    ++   K         Q ++  ++  +LG 
Sbjct: 225 FFTFGSAFSYENAK-------IKQDEICGSICEILGL 254
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  196 bits (494), Expect = 2e-48
 Identities = 125/438 (28%), Positives = 185/438 (41%), Gaps = 55/438 (12%)

Query: 34  SNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKIFERAVIVIIDALR 93
           +    +  F   F  R+ VL              +          + F++ V VIIDALR
Sbjct: 12  AQLLAILLFIFAFFPRKIVLT------GISKQDPDQDRDLQR--DRPFQKLVFVIIDALR 63

Query: 94  YDFLI--PYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQRLKGLTTGSLPT 151
            DFL     +  N  H    T           ++     A+ PT T  RLK +TTGS P+
Sbjct: 64  SDFLFDSQISHFNNVHQWLNT---------GEAWGYTSFANPPTVTLPRLKSITTGSTPS 114

Query: 152 FIDLGSNFAGTN-----IDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNETLSQPAFS 206
           FIDL  N A         + D+ L Q+   +  I  +GDDTW  LF        + P  S
Sbjct: 115 FIDLLLNVAQDIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQW-FDFADPTHS 173

Query: 207 FNVPDLHGVDNKVNQYVFDYIKDA--NFDVLIAHYLGVDHVGHRLGPDHPTMRDKLNQMD 264
           F V D   VDN V + +   +      +DV I HYLG+DH+GH+ GP    M  K  +MD
Sbjct: 174 FFVSDFTQVDNNVTRNLPGKLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMD 233

Query: 265 RCVKEMMDLL-----DDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLWMYSKKP------ 313
             +K + D +     DD TL+ V+GDHGM+  GNHGG S  E ++ L   S K       
Sbjct: 234 SILKSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARP 293

Query: 314 ------TFGYLKQP----GKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGDE 363
                 T      P      + +  Q+D+VPT++ L G PIP  ++G +IP+      ++
Sbjct: 294 ESQVNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLPNK 353

Query: 364 YLSKAQKINIGQLNRFFSEYD--LDASDFLSSSVHKNNNSYLDQYFLDFDYARDAFSYFK 421
             S  +  N   L +  S++   +   DF +  +      Y  Q  L        +    
Sbjct: 354 LASMKE--NFMHLWK-LSDHHGEVALDDFTAEDI--YTKMYTIQETLTKSATNYNYPLLT 408

Query: 422 AIWAEFSLFPMIIGFLLL 439
             +  F +  +I  ++LL
Sbjct: 409 LAFVGFLIITIIAIYVLL 426
 Score = 34.6 bits (79), Expect = 7.2
 Identities = 73/426 (17%), Positives = 132/426 (30%), Gaps = 49/426 (11%)

Query: 491 EFYVLLPSFYILLNSFNQKLMEYFKGFVKLDYF--------SIFITFLHVCSFGSNSFTV 542
             Y LL   ++         +     +   D++         + ++ +   S  ++SF  
Sbjct: 402 YNYPLLTLAFVGFLIITIIAIYVLLRYSGPDFWQLRVSSLSVLLVSIILGVSTFASSFIE 461

Query: 543 WEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALA---FILLQVISSYVTNCREEQG 599
            E +L  +++                PLF       +    FI++  + S        Q 
Sbjct: 462 EEHQLWWWIVTAF----------SAVPLFVYRLNVLIIVRWFIMMACVRSIKFWNNSGQ- 510

Query: 600 AFCVSTYISTPDNSLRTL---------IVLALMALSSIILPLILQLHLRRVLGLSLKLYH 650
            F  S  +S   N   +          +VL + +    +L  I+   L  +       + 
Sbjct: 511 KFIYSNVMSNLLNQNPSWKWCLNMLTFLVLIMASAGFQVLHFIVTTILVGLCFTYKISWE 570

Query: 651 LSILYFFELISSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICILGVLIWQFFLLSRS 710
           +         + I    H + A       + + ++  LA  +      V+I +  L    
Sbjct: 571 IVN----GNQAEIPLFMHDLLAKIDFAPTESNLIV--LARVFFQAWAIVVISRLVLTKLK 624

Query: 711 KFAKINVIERSYFVFALLYSFLSFLQRPLGHLSLFSCF-LQILLLIQLKQWQPSVG-HNF 768
              K  +I+       +L  F +  Q  +G   +F     QI    Q             
Sbjct: 625 VLNKNYLIKDMKVYITILLMFQTSSQN-IGQFLVFQILESQIFYFFQNIPTASLTSTSKI 683

Query: 769 FSVTLGLLGLS--HFFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPI-- 824
           +   L  L L    FF  G   +IS++D   A+    S  N  +  I M +      I  
Sbjct: 684 YFSNLVSLILQNFTFFQFGGTNSISTIDLGNAYHGVSSDYNIYVVGILMSVANFAPAIYW 743

Query: 825 -LTCISIPLFSFEPLSKKNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVF 883
            +   SI   S     K   F     R       Y+ +  T  +      R HL +W VF
Sbjct: 744 SMLPWSINYASIPAQVKLQTF----IRSKLPAFTYHCIFGTCLMTACVVLRFHLFIWSVF 799

Query: 884 APRFML 889
           +P+   
Sbjct: 800 SPKLCY 805
>sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CHROMOSOME I
 pir||S62432 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 pir||T37638 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91096.1| (Z54308) putative major facilitator superfamily protein
           [Schizosaccharomyces pombe]
          Length = 758

 Score =  181 bits (456), Expect = 4e-44
 Identities = 106/395 (26%), Positives = 163/395 (40%), Gaps = 51/395 (12%)

Query: 20  KYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPK 79
           ++    IF         +G   F  GF   +      +                      
Sbjct: 2   RFAFFGIF-----WLQIFGSILFLLGFFPHKNDSTGKA----MSNQFSPPAVIDQ----- 47

Query: 80  IFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQ 139
                V V++DALR DF+   + +  +  +        + +  +       A +PT T  
Sbjct: 48  ----VVFVMVDALRADFVFSKSHNMPFTQSL-------LYNSTHGIGFSAFARSPTVTMP 96

Query: 140 RLKGLTTGSLPTFIDLGSNFAG----TNID-EDNLLLQWKSLDKQIVLLGDDTWDVLFHD 194
           RLK LTTG++P F+D+  N A     ++I+ +D+ + Q  S +K+I   GDDTW  LF  
Sbjct: 97  RLKALTTGTIPGFLDVLLNIAESDTGSSIEAQDSWVYQLNSFNKKIEFYGDDTWLKLFPS 156

Query: 195 YLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYI---KDANFDVLIAHYLGVDHVGHRLGP 251
             ++       SF V D   VDN V +     +      ++D LI HYLGVDH+GH  GP
Sbjct: 157 AFSKFEG--TTSFFVSDYTEVDNNVTRNFDHALPSSLSHSWDALILHYLGVDHIGHLYGP 214

Query: 252 DHPTMRDKLNQMDRCVKEMMDLL---DDSTL----LIVMGDHGMDNKGNHGGDSFDEINS 304
             P +  KL ++D  +  +   L   D+ T     +++ GDHGM+  GNHGG S  E  +
Sbjct: 215 SSPLLNIKLLEIDTIISRIYKYLQEYDEKTNTHSLIVLCGDHGMNEVGNHGGSSSGETTA 274

Query: 305 VLWMYSKKPTFG-YLKQ--PGKV------LSANQVDLVPTLSLLLGNPIPYGNLGTLIPE 355
            L +           K                 QVD+VPT+ LLLG PIP GN+G ++  
Sbjct: 275 ALSLLFPSNELSHINKPILNMDDNPYSILERVEQVDVVPTICLLLGIPIPKGNMGKVLSP 334

Query: 356 PFYYYGDEYLSKAQKINIGQLNRFFSEYDLDASDF 390
               + D   +K   ++            L  S+ 
Sbjct: 335 VTELWKDTKTAKMAALSNLFQLSLLKNPSLTTSEL 369
 Score = 36.1 bits (83), Expect = 2.5
 Identities = 38/176 (21%), Positives = 57/176 (31%), Gaps = 28/176 (15%)

Query: 727 LLYSFLSFLQRPL-----GHLSLFSCFLQILL---LIQLKQWQPSVGHNFF--SVTLGLL 776
           LL SFLS   +P        LSLF   L  L    L  L              +  +  +
Sbjct: 579 LLISFLS---KPTFKQLRCQLSLFILLLTRLENMGLYLLYDIWQRTMPEEGTLASVMYYV 635

Query: 777 GLS-HFFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMFLHTVGAPILTCISIPLFSF 835
                FF+ GN  +++++D + A+    S     I A+ + L T          +     
Sbjct: 636 AEQVAFFSLGNSNSLATVDLSQAYTGLDSYN---IFAVGILLFTSVFAGALWWCLHQPKR 692

Query: 836 EPLSKKNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRHLMVWKVFAPRFMLSG 891
                        F    S  L      T         R HL VW VF+P+ + + 
Sbjct: 693 MMDRSVK-----TFWIMSSISL------TFLCISCFIMRHHLFVWSVFSPKLLYNA 737
CPU time:   252.72 user secs.	    3.11 sys. secs	  255.83 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.316    0.171    0.472 

Gapped
Lambda     K      H
   0.270   0.0601    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 577666678
Number of Sequences: 887402
Number of extensions: 30149002
Number of successful extensions: 146909
Number of sequences better than 10.0: 1572
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 1458
Number of HSP's that attempted gapping in prelim test: 143920
Number of HSP's gapped (non-prelim): 3501
length of query: 918
length of database: 277,845,442
effective HSP length: 54
effective length of query: 864
effective length of database: 229,925,734
effective search space: 198655834176
effective search space used: 198655834176
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 78 (34.4 bits)