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GPI Anchor Biosynthesis Report: NP_197227.1 (PIG-O family, Arabidopsis thaliana)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (884 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 5

Distribution of 71 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments: (bits) Value
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 931 0.0
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 648 0.0
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 646 0.0
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 633 e-180
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 619 e-176
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 615 e-175
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 565 e-160
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 535 e-150
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 529 e-149
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 527 e-148
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 410 e-113
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 409 e-113
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 394 e-108
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 393 e-108
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 393 e-108
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 381 e-104
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 378 e-103
sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CH... 357 6e-97
gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster] 339 1e-91
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 335 2e-90
ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis ele... 327 5e-88
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 326 1e-87
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 316 1e-84
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 308 2e-82
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 307 7e-82
gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melano... 302 1e-80
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 264 4e-69
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 262 2e-68
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 260 9e-68
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 256 9e-67
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 256 1e-66
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 246 1e-63
ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyro... 243 1e-62
gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase... 240 5e-62
ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyro... 240 6e-62
dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens] 238 4e-61
ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phos... 238 4e-61
pir||T33724 hypothetical protein - Zymomonas mobilis >gi|3089614... 236 1e-60
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 233 8e-60
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 230 9e-59
ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo ... 218 2e-55
dbj|BAB17014.1| (AB050262) hypothetical protein [Macaca fascicul... 218 3e-55
dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharom... 192 2e-47
pir||A55144 autotaxin precursor - human >gi|537906|gb|AAA64785.1... 185 3e-45
dbj|BAB55130.1| (AK027465) unnamed protein product [Homo sapiens] 175 2e-42
ref|NP_060203.1| (NM_017733) hypothetical protein FLJ20265 [Homo... 175 2e-42
ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phos... 169 2e-40
ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster] 166 9e-40
Alignments
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  931 bits (2382), Expect = 0.0
 Identities = 884/884 (100%), Positives = 884/884 (100%)

Query: 1   METYLKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHD 60
           METYLKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHD
Sbjct: 1   METYLKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHD 60

Query: 61  SSSEPKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNS 120
           SSSEPKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNS
Sbjct: 61  SSSEPKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNS 120

Query: 121 FGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCI 180
           FGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCI
Sbjct: 121 FGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCI 180

Query: 181 EHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGP 240
           EHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGP
Sbjct: 181 EHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGP 240

Query: 241 GGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNK 300
           GGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNK
Sbjct: 241 GGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNK 300

Query: 301 DGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSA 360
           DGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSA
Sbjct: 301 DGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSA 360

Query: 361 ANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHI 420
           ANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHI
Sbjct: 361 ANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHI 420

Query: 421 LMDRNGDDGSTDISALLKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFGILVISLIL 480
           LMDRNGDDGSTDISALLKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFGILVISLIL
Sbjct: 421 LMDRNGDDGSTDISALLKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFGILVISLIL 480

Query: 481 QFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIK 540
           QFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIK
Sbjct: 481 QFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIK 540

Query: 541 LRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALT 600
           LRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALT
Sbjct: 541 LRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALT 600

Query: 601 YAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIGLV 660
           YAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIGLV
Sbjct: 601 YAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIGLV 660

Query: 661 QLCLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLE 720
           QLCLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLE
Sbjct: 661 QLCLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLE 720

Query: 721 GVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLI 780
           GVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLI
Sbjct: 721 GVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLI 780

Query: 781 RQAILLTIETFGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTA 840
           RQAILLTIETFGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTA
Sbjct: 781 RQAILLTIETFGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTA 840

Query: 841 TILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAYYL 884
           TILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAYYL
Sbjct: 841 TILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAYYL 884
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  648 bits (1656), Expect = 0.0
 Identities = 219/954 (22%), Positives = 370/954 (37%), Gaps = 154/954 (16%)

Query: 12  ALGFLLIH---AIAILIFTRGFLLTRTELPFHSTCSDVSLSP--------CLASPRSNHD 60
            +  LL+     +A+ IF  GFLL R E+   S+CSD    P                  
Sbjct: 4   IIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILV 63

Query: 61  SSSE----------------PKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLK 104
            +                     +  ++  ++ L  + + S  I    ADPPTT+LQRLK
Sbjct: 64  DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVS--IGTLLADPPTTTLQRLK 121

Query: 105 GLTTGGLPTFIDIGNSFGAPA-IVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYP 163
            LTTG LPTFID G++F   A I ED+F+ Q    GK + ++GDDTW  LFPNQF K+  
Sbjct: 122 ALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTAA 181

Query: 164 FPSFNVKDLDTVDNGCIEHLF------------------PTLFKDDWDVLIAHFLGVDHA 205
           + SF++ DL+TVD+     +F                    +   +  ++IAHFLGVDH 
Sbjct: 182 YDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHC 241

Query: 206 GHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGG 265
           GH FG     M + L + + ++ + I  ++S                 DHG T  GDHGG
Sbjct: 242 GHKFGPSHPVMADTLRKMDRIIGQTIETMKSD----------------DHGMTSTGDHGG 285

Query: 266 GTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQMCISYIEQQHCQLCLGYPFLS 325
            +  E+   +   S K H  ++P                  I  +      + L  PF +
Sbjct: 286 ESENEIRAGILVHSKK-HQIILPE------------RPIHQIDIVPTISLLMGLPIPFSN 332

Query: 326 EGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSAANEWMKHYVDVLCVNAWQVKRYIDV 385
            G  I  +           W + +  +G F  Q +   + + Y                 
Sbjct: 333 LGTVITQLFT------RDLWEIARQMMG-FVWQDSVGIFAETYAAQKNFGELHS----HT 381

Query: 386 YSNSSVVGFSSDDMSRISDL----YSAAEQNWSNSVKHILMDRNGDDGSTDISAL----L 437
             +S+ +    D MSRI  L    ++  +  + N+    L++      + ++ +L     
Sbjct: 382 IRDSNTMEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFSLVEAIMFLITNEVMSLEWIIY 441

Query: 438 KE----QIAEYLNFFSSVVELARSKWTEFNLNLMITGFGILVISLILQFLAVFHG--DKS 491
           +       A  L   +     AR       L LM      L +S +   +++ H      
Sbjct: 442 RTGCGLLQAALLTDKTDSDGSAR------TLLLMT-----LAVSCLSSIISMCHKALQIR 490

Query: 492 YAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLAT----TGLIKLRYSVMR 547
            ++ S LS      + ++ I + S  SNSY++ E +V  + L +      L KLR + +R
Sbjct: 491 ISIKSMLSAKVIGPILVI-IHSISLFSNSYVVYEAQVVRYFLQSLVTLVFLEKLRSTALR 549

Query: 548 KTMRKEAFMFLAMV-----FVLRVSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALTYA 602
                +       V      ++   I +GL  +    +         +G    +P+    
Sbjct: 550 PRKPFKLNFLWKFVNQDQNLIIFTLIMVGLRSEPIFHRCREEE----VGCDTYYPSRQAG 605

Query: 603 IEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIGL--- 659
                   V +L  +  +A+A   N  V+KY  +     Q+     R  +T+ ++     
Sbjct: 606 SLTRDAQVVRLLFALGSLAVA---NLSVFKYYGLRDTKSQIESNSKRSSETIRILSATSW 662

Query: 660 VQLCLLASARMFCT-EKDKNWAIRTVALVSACSSPIILLSGKQGS-------MLALVYLV 711
           + + ++    +F +   D + A  +   +S  S    +L+ ++G+       +L  VY++
Sbjct: 663 LHIAIIVLHSVFASLTHDVSRANLSAHSLSVISLICAVLAWREGNSAICAHFLLMPVYIL 722

Query: 712 AGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAF 771
            G  ++    +            S+      +   LL    F+  GH      + + AAF
Sbjct: 723 FGDGLIPAIIIFIAVSVLIAEFVSREFIASTIA--LLIPLGFYHLGHSPVISSIPWNAAF 780

Query: 772 VGFDEFVLIRQ-AILLTIETFGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLF 830
           VG      +R    L  +    FS I S+F    +I   S++ Q            + L 
Sbjct: 781 VGIPGGTALRVLPALFVLFHLNFSAISSIF----VISSESESSQK----MSAPNTAWTLT 832

Query: 831 GVISATTVTATILCVT--IQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAY 882
             +   T+ AT+ C+   I RRHLMVW +FAPKF+F+ +  I+          Y
Sbjct: 833 ETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIVFIFSANFFLIY 886
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  646 bits (1649), Expect = 0.0
 Identities = 163/941 (17%), Positives = 307/941 (32%), Gaps = 135/941 (14%)

Query: 6   KNKKLTALGFLLIHAIAILIFTRGFLL-TRTELPFHSTCSDVSLSPCLASPRSNHDSSSE 64
           K+  +  +G L       ++F  GF   + +     ST  +   +  L    +    + +
Sbjct: 5   KSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPAYD 64

Query: 65  P------KPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIG 118
                      D      ++  A   + +  K   D PT ++ RLK +TTG L  FIDI 
Sbjct: 65  SFVLLLVDALRDDFPDATSMPVAYSRACEKLKLHVDIPTVTMPRLKSITTGTLSNFIDIA 124

Query: 119 NSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYP-FPSFNVKDLDTVDN 177
            + G    ++D+F+++L    + +   GD TW +LFP++F +      SF V D    D 
Sbjct: 125 LNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYVNDFYEGDR 184

Query: 178 GCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQ 237
              + L   L + DW +LI H+LG+DH GH+ G  S  +  KL++ + V++K+   L+ +
Sbjct: 185 NVTKTLETELERSDWSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVVKKI---LDHK 241

Query: 238 AGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCK 297
           + P     N +L++ GDHG    G HGG T  E    ++              ++  S  
Sbjct: 242 SFP-----NVLLMLTGDHGMADGGGHGGNTPAETLVPLYLY------------YNNCSKT 284

Query: 298 QNKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPEL---------YALGSSSWNLD 348
            +   +   I         L +  P LS G  I  +   L         +       N  
Sbjct: 285 PSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKA 344

Query: 349 KSDLG--------------NFGTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGF 394
           +   G              N          ++   +     A QV       +  + +  
Sbjct: 345 RVKFGHEIVHRSDYYTWYQNATLLHKK--LLRPLREGDGGGASQVY---YQNAKLNYMRL 399

Query: 395 SSDDMSRISDLYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFSSVVEL 454
             D +       S       N   H L           I  L+   IA YL      V  
Sbjct: 400 QLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTI---DVAQ 456

Query: 455 ARSKWTEFNLNLMITGFGI-LVISLILQFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRA 513
           A  K     L        I L + L+  +                            IR 
Sbjct: 457 ALLKIALPPLYTRRLKISIPLPLPLLACY---------------------------AIRT 489

Query: 514 CSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLT 573
            +  S+S+I  E     +L  T  L+    ++  +  +    +    ++ +  +    + 
Sbjct: 490 LTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTIASTCLWQMR 549

Query: 574 KQAATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLY----VAIAKAPNEG 629
           K       ++               L        I S+++L   L+    +  + A    
Sbjct: 550 KVLVVLMLLTLMR--------YIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLASGAA 601

Query: 630 VWKYVTVGSMLLQVTGGRNRIPQTVYVIG---LVQLCLLASARMFCTEKDKNWAIRTVAL 686
           ++       +  QV            ++    ++  C LA   M            +   
Sbjct: 602 LFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYR-AALPQAHSFGK 660

Query: 687 V--------------SACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQS 732
           V              ++      LL      +L  V LVA     +L  V     +  + 
Sbjct: 661 VPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVY---GTSARK 717

Query: 733 KFSKLN-PLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIETF 791
              +L     ++    L+   FF  G+  +   +     ++G   +     AI +T+ T+
Sbjct: 718 FSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLNTY 777

Query: 792 GFSIILSVFGLPLLIPFHSQ---------TPQAHGEKRHQLFQMYMLFGVISATTVTATI 842
              I   ++ +   +    +               +          L+  +        +
Sbjct: 778 SADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAP-----LYAALIMLPAAFYL 832

Query: 843 LCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAYY 883
             +   R HL ++ +F+PK ++D   +++  L+  + S Y+
Sbjct: 833 CLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYF 873
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  633 bits (1616), Expect = e-180
 Identities = 212/937 (22%), Positives = 364/937 (38%), Gaps = 114/937 (12%)

Query: 3   TYLKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHDSS 62
            Y++     A+  L+ +   +  FT GFLL R  L   S C +      +   +++    
Sbjct: 20  KYIQACIFFAI-ILISNFYGLKSFTDGFLLRRAVLNQTSLCEN--PPADVREWKNSSGCW 76

Query: 63  SEPKPWMDKLTILQTLAFAN------------------------DSSAKIFKAFADPPTT 98
           +        + I+  L +                            ++ + +  AD PTT
Sbjct: 77  APKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTT 136

Query: 99  SLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQF 158
           + QRLKGLTTG LPTFID+G++F    I EDN + Q     K++V++GDDTW  LF +  
Sbjct: 137 TSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYL 196

Query: 159 QK--SYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPM 216
            +  S P  SFNV DL  VDN   +++F  +   ++DVLIAH+LGVDH GH  G D   M
Sbjct: 197 NETLSQPAFSFNVPDLHGVDNKVNQYVFDYIKDANFDVLIAHYLGVDHVGHRLGPDHPTM 256

Query: 217 INKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMF 276
            +KL Q +  +++++++L          ++T+LIVMGDHG    G+HGG + +E+ + ++
Sbjct: 257 RDKLNQMDRCVKEMMDLL---------DDSTLLIVMGDHGMDNKGNHGGDSFDEINSVLW 307

Query: 277 AMSTKKHTTLVPPEFDTSSCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPE 336
             S K     +            K      +  +      L    P+ + G  I      
Sbjct: 308 MYSKKPTFGYLKQ--------PGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPE---P 356

Query: 337 LYALGSSSWNLDKSDLGNFGTQSAANEWMKHYVDVLCVNAWQ-VKRYIDVYSNSSVVGFS 395
            Y  G     L K+   N G     N +   Y     ++A   +   +   +NS  +   
Sbjct: 357 FYYYG--DEYLSKAQKINIGQL---NRFFSEY----DLDASDFLSSSVHKNNNSY-LDQY 406

Query: 396 SDDMSRISDLYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFSSVVELA 455
             D     D +S  +  W+      ++   G          L   + +    F     +A
Sbjct: 407 FLDFDYARDAFSYFKAIWAEFSLFPMI--IGFLLLIIGGFNLALLMQDKSVIFRMSANMA 464

Query: 456 RSKWTEFNLNLMIT------------GFGILVISLILQFLAVFHGDKSYAVGSWLSTGAA 503
            S      + L++              F +L+ S  +  L  F+         ++     
Sbjct: 465 PSVMKCLPVCLILILANNELHSPFPAEFYVLLPSFYI-LLNSFNQKLMEYFKGFVKLD-Y 522

Query: 504 FTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRY--SVMRKTMRKEAFMFLAMV 561
           F++FI  +  CSF SNS+ + E ++ +FL+ T GL+      S M        +  LA +
Sbjct: 523 FSIFITFLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAFI 582

Query: 562 FVLRVSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLYVA 621
            +  +S  +   ++   +  +S+  S      PD+   T  +     LS +IL  +L + 
Sbjct: 583 LLQVISSYVTNCREEQGAFCVSTYIS-----TPDNSLRTLIVLALMALSSIILPLILQLH 637

Query: 622 IAKAPNEGVWKYV--------TVGSML---LQVTGGRNRI-PQTVYVIGLVQ----LCLL 665
           + +     +  Y          + S+      V      +  Q  +V+  +     +C+L
Sbjct: 638 LRRVLGLSLKLYHLSILYFFELISSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICIL 697

Query: 666 -ASARMFC--TEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGV 722
                 F   +                 +     LS  Q  +  L        I+ L  +
Sbjct: 698 GVLIWQFFLLSRSKFAKINVIERSYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQL 757

Query: 723 ERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEF-VLIR 781
           ++   S G + FS       V   LL +  FF +G+  A   L +  AF+          
Sbjct: 758 KQWQPSVGHNFFS-------VTLGLLGLSHFFTTGNQAAISSLDWNFAFIHSKSAENQAI 810

Query: 782 QAILLTIETFGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTAT 841
            AI + + T G  I+  +        F  +           LF+    F + +    T+T
Sbjct: 811 SAIFMFLHTVGAPILTCISIPL----FSFEPLSKKNRFLINLFRFSFSFILYNLLISTST 866

Query: 842 ILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICL 878
           +      RRHLMVW +FAP+F+   + L+   L + +
Sbjct: 867 VFFAGFFRRHLMVWKVFAPRFMLSGILLVTHQLFVLI 903
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score =  619 bits (1580), Expect = e-176
 Identities = 98/866 (11%), Positives = 216/866 (24%), Gaps = 125/866 (14%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSL-SPCLASPRSNHDSSSEPKPW 68
              LG L+       IF   +  +      H      +   P                  
Sbjct: 4   FFTLGLLIHFVFFASIF-DIYFTSPLV---HGMTPQFTPLPPPARRLVLFVADGLRADAL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDENGNSRAPFIRNIIM---HEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F  +D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDAT 172

Query: 174 TVDNGCIEHLFPTL------------FKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    +++                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  +++++++        G    T  I   DHG T  G HG G   E  T +      
Sbjct: 233 KVDDGVKEIVSMFNHFY---GNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   +FD +  K+      K                + + +P  S G       
Sbjct: 290 IKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D    N  +
Sbjct: 345 -PVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               +  L       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGF------------------GILVISL 478
           L   I  + N    V +  +        + +  G                   G+L + +
Sbjct: 461 L--IIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPI 518

Query: 479 ILQFLAVFH--GDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L  F    D   +V ++  +     L      + +   SF              ++
Sbjct: 519 WYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LA---TTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L    T        + +    +  +  +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L       +L     ++  E   +  + +L  VL + +  +    + +   +  M   +
Sbjct: 628 LLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQII 687

Query: 644 TGGRNRIPQTVYVIGL--VQLCLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +         V ++    +   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCA 761
              L    +     +  ++       +  +  +             L    FF +G+  +
Sbjct: 748 QETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTA-FFGTGNIAS 806

Query: 762 FDGLRYGAAFVGFDEFVLIRQAILLT 787
            +     + +     F       L+ 
Sbjct: 807 INSFDLASVYCFLTVFSPFMMGALMM 832
 Score =  619 bits (1580), Expect = e-176
 Identities = 98/866 (11%), Positives = 216/866 (24%), Gaps = 125/866 (14%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSL-SPCLASPRSNHDSSSEPKPW 68
              LG L+       IF   +  +      H      +   P                  
Sbjct: 4   FFTLGLLIHFVFFASIF-DIYFTSPLV---HGMTPQFTPLPPPARRLVLFVADGLRADAL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDENGNSRAPFIRNIIM---HEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F  +D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDAT 172

Query: 174 TVDNGCIEHLFPTL------------FKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    +++                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  +++++++        G    T  I   DHG T  G HG G   E  T +      
Sbjct: 233 KVDDGVKEIVSMFNHFY---GNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   +FD +  K+      K                + + +P  S G       
Sbjct: 290 IKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D    N  +
Sbjct: 345 -PVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               +  L       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGF------------------GILVISL 478
           L   I  + N    V +  +        + +  G                   G+L + +
Sbjct: 461 L--IIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPI 518

Query: 479 ILQFLAVFH--GDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L  F    D   +V ++  +     L      + +   SF              ++
Sbjct: 519 WYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LA---TTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L    T        + +    +  +  +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L       +L     ++  E   +  + +L  VL + +  +    + +   +  M   +
Sbjct: 628 LLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQII 687

Query: 644 TGGRNRIPQTVYVIGL--VQLCLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +         V ++    +   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCA 761
              L    +     +  ++       +  +  +             L    FF +G+  +
Sbjct: 748 QETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTA-FFGTGNIAS 806

Query: 762 FDGLRYGAAFVGFDEFVLIRQAILLT 787
            +     + +     F       L+ 
Sbjct: 807 INSFDLASVYCFLTVFSPFMMGALMM 832
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  615 bits (1571), Expect = e-175
 Identities = 175/913 (19%), Positives = 317/913 (34%), Gaps = 130/913 (14%)

Query: 9   KLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSN---------- 58
             T  G L +  I + IF  GF   +  L   S         C +S  SN          
Sbjct: 13  IFTVAGIL-LQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKL 71

Query: 59  -----HDSSSEPKP------------WMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQ 101
                       +               + +   Q+L    D  A  + A A PPT ++ 
Sbjct: 72  RLLYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGD--AIGYHAKAAPPTVTMP 129

Query: 102 RLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKS 161
           RLK + +G +  F+D+  +F   A+++DN + Q    G ++VM+GD+TW +LFP  F + 
Sbjct: 130 RLKAMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRH 189

Query: 162 YPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
               SF VKD   VD     HL   L  DDW++LI H+LG+DH GH  G +S  M  KL+
Sbjct: 190 DGVSSFFVKDTVQVDRNVSRHLPDELNSDDWNLLILHYLGLDHVGHTGGRNSPLMPAKLK 249

Query: 222 QYNSVLEKVINILESQAGPGGLHE--NTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMS 279
           + + ++      +  +A     H+   T+LI++ DHG T NG+HGG + EE ++ M  + 
Sbjct: 250 EMDDIVR----TMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIG 305

Query: 280 TKKHTTLVPPEFDTSSCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN----- 334
                       + S      +     +           +  P  + G  +         
Sbjct: 306 LN---------SNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRD 356

Query: 335 -PELYALGSSSWNLDKSDL----GNFGTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNS 389
             +L AL  +SW L +  L     +   + + N ++    + L ++  +           
Sbjct: 357 FEQLRALELNSWQLLRLMLAQIQSSSFPRVSCNCFLDGTCEGLDLDISECSG-------- 408

Query: 390 SVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFS 449
                  D   ++  L+  A         H +        S+         +  Y  F  
Sbjct: 409 -------DKEKQLICLFRNAAAL------HGIWKSKKSTESSSTMEDFSRALDAYNTFLK 455

Query: 450 SVVELARSKWTEFNLNLMITGFGILVISLILQ---FLAVFH------GDKSYAVGSWLST 500
           +  E   SK TE  + L+  G   +++S  +    FL++F        D+  ++ + L+ 
Sbjct: 456 TASEWLASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNL 515

Query: 501 GAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAM 560
              F   ++ I   S  S+S + EE  + +F+++T  L+ L  +     + K   +    
Sbjct: 516 EEVFIFALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDF 575

Query: 561 VFVLRVSIDIGLTKQAATSQ------FMSSSPSWML-GIAPDHPALTYAIEIAPI----- 608
            F    S+ I         Q      ++     W++ G +     +     I  I     
Sbjct: 576 KFGSIFSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLY 635

Query: 609 ---------LSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIGL 659
                      V IL    +          V +Y      L    G    +    Y++ +
Sbjct: 636 TLFRTGSNRKGVRIL-AFGFSTCGFLVLLHVGRY---QDELSTGFGATVTVKVIYYLLSI 691

Query: 660 VQLCLLASARMFCTEKDKNWAIRTVALVSACSSP---IILLSGKQGSMLALVYLVAGYCI 716
             +            KDK++    +A V  C        +L       L    + +G  +
Sbjct: 692 SSIGASLVLPWSALNKDKSF----LAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPIL 747

Query: 717 MRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDE 776
           + L  +                      +  + +   FA G+      +    AF+G   
Sbjct: 748 LLLLQILAILCLSSSDFQVNEWVEITALYY-MGMAGHFALGNSNTLATIDVAGAFIGISS 806

Query: 777 FVLIRQAILLTIETFGFSIILSVFGLPLL---IPFHSQTPQAHGEKR---------HQLF 824
              I   IL+ + T+   ++  +  +  +   +  HS +  +   +            L 
Sbjct: 807 HSTILSGILMFMITYASPMLFLLSLVMYIGANLRNHSNSTISTHRETTKARVPLPCSALH 866

Query: 825 QMYMLFGVISATT 837
           Q+  L  +    T
Sbjct: 867 QLNTLDRIYCGLT 879
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  565 bits (1443), Expect = e-160
 Identities = 99/866 (11%), Positives = 213/866 (24%), Gaps = 127/866 (14%)

Query: 15  FLLIHAIAILIFTRGFLLTRTELPFHS-----TCSDVSL-SPCLASPRSNHDSSSEPKPW 68
            LL  A+ +LI    F ++  ++ F S          +   P                  
Sbjct: 1   MLLFFALGLLIH-FVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LGVD  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D   ++  +
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               + DL       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFG------------------ILVISL 478
           L   I  + N      +  +        + + TG                    +L + +
Sbjct: 461 L--IIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 479 ILQFL--AVFHGDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L       D   ++ ++  +     L +    + +   SF              ++
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LAT---TGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L             + +    +     +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L        L             +L + +L  VL + +  + +  + K   +  M   V
Sbjct: 628 LLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIV 687

Query: 644 TGGRNRIPQTVYVIGLVQL--CLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +           ++    L   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCA 761
              L    +     +  ++       +  +                L    FF +G+  +
Sbjct: 748 QETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTA-FFGTGNIAS 806

Query: 762 FDGLRYGAAFVGFDEFVLIRQAILLT 787
            +     + +     F       L+ 
Sbjct: 807 INSFDLASVYCFLTVFSPFMMGALMM 832
 Score =  564 bits (1439), Expect = e-159
 Identities = 97/866 (11%), Positives = 209/866 (23%), Gaps = 124/866 (14%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSL-SPCLASPRSNHDSSSEPKPW 68
           L     LLIH +  +     +  +      H      +   P                  
Sbjct: 3   LFFALGLLIHFVFFVSIFDIYFTSPLV---HGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LGVD  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D   ++  +
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               + DL       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFG------------------ILVISL 478
           L   I  + N      +  +        + + TG                    +L + +
Sbjct: 461 L--IIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 479 ILQFL--AVFHGDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L       D   ++ ++  +     L +    + +   SF              ++
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LAT---TGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L             + +    +     +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L        L             +L + +L  VL + +  + +  + K   +  M   V
Sbjct: 628 LLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIV 687

Query: 644 TGGRNRIPQTVYVIGLVQL--CLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +           ++    L   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCA 761
              L    +     +  ++       +  +                L    FF +G+  +
Sbjct: 748 QETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTA-FFGTGNIAS 806

Query: 762 FDGLRYGAAFVGFDEFVLIRQAILLT 787
            +     + +     F       L+ 
Sbjct: 807 INSFDLASVYCFLTVFSPFMMGALMM 832
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  535 bits (1365), Expect = e-150
 Identities = 93/825 (11%), Positives = 201/825 (24%), Gaps = 126/825 (15%)

Query: 15  FLLIHAIAILIFTRGFLLTRTELPFHS-----TCSDVSL-SPCLASPRSNHDSSSEPKPW 68
            LL  A+ +LI    F ++  ++ F S          +   P                  
Sbjct: 1   MLLFFALGLLIH-FVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LGVD  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D   ++  +
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               + DL       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFG------------------ILVISL 478
           L   I  + N      +  +        + + TG                    +L + +
Sbjct: 461 L--IIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 479 ILQFL--AVFHGDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L       D   ++ ++  +     L +    + +   SF              ++
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LAT---TGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L             + +    +     +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L        L             +L + +L  VL + +  + +  + K   +  M   V
Sbjct: 628 LLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIV 687

Query: 644 TGGRNRIPQTVYVIGLVQL--CLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +           ++    L   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWS 746
              L    +     +  ++       +  +             + 
Sbjct: 748 QETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLFF 792
 Score =  533 bits (1361), Expect = e-150
 Identities = 91/825 (11%), Positives = 197/825 (23%), Gaps = 123/825 (14%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSL-SPCLASPRSNHDSSSEPKPW 68
           L     LLIH +  +     +  +      H      +   P                  
Sbjct: 3   LFFALGLLIHFVFFVSIFDIYFTSPLV---HGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LGVD  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D   ++  +
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               + DL       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFG------------------ILVISL 478
           L   I  + N      +  +        + + TG                    +L + +
Sbjct: 461 L--IIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 479 ILQFL--AVFHGDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L       D   ++ ++  +     L +    + +   SF              ++
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LAT---TGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L             + +    +     +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L        L             +L + +L  VL + +  + +  + K   +  M   V
Sbjct: 628 LLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIV 687

Query: 644 TGGRNRIPQTVYVIGLVQL--CLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +           ++    L   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWS 746
              L    +     +  ++       +  +             + 
Sbjct: 748 QETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLFF 792
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  529 bits (1350), Expect = e-149
 Identities = 86/756 (11%), Positives = 195/756 (25%), Gaps = 110/756 (14%)

Query: 112 PTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYP 163
                +   +    +  D+  N+     K     G      +F           +     
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAK 56

Query: 164 FPSFNVKDLDTVDNGCIEHLFPTL------------FKDDWDVLIAHFLGVDHAGHIFGV 211
              F  +D   +D    +++                  ++  V   H LG+D  GH    
Sbjct: 57  REDFGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRP 116

Query: 212 DSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEV 271
            S    + +++ +  +++++++        G    T  I   DHG T  G HG G   E 
Sbjct: 117 SSRDYKHNIKKVDDGVKEIVSMFNHFY---GNDGKTTFIFTSDHGMTDWGSHGAGHPSET 173

Query: 272 ETTMFAMSTKKHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFL 324
            T +            +   +FD +  K+      K                + + +P  
Sbjct: 174 LTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLN 233

Query: 325 SEGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHY 368
           S G         +  L ++     +S   N                           K  
Sbjct: 234 SVGIL------PVDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLL 287

Query: 369 VDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NG 426
            D    N  +  R    Y               +  L       +    +  L      G
Sbjct: 288 SDSKQFNILRKARS---YIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIG 344

Query: 427 DDGSTDISALLKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGF--------------- 471
             G    ++LL   I  + N    V +  +        + +  G                
Sbjct: 345 FVGWISYASLL--IIKSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTY 402

Query: 472 ---GILVISLILQFLAVFH--GDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYI 522
              G+L + +    L  F    D   +V ++  +     L      + +   SF      
Sbjct: 403 YVYGLLPLPIWYAVLREFQVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFF----- 457

Query: 523 LEEGKVANFLLA---TTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAAT 578
                   ++L    T        + +    +  +  +     +L V  +   + ++   
Sbjct: 458 ------YRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDI 511

Query: 579 SQFMSSSPSWMLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKY 633
           S  M +    +L       +L     ++  E   +  + +L  VL + +  +    + + 
Sbjct: 512 SLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRK 571

Query: 634 VTVGSMLLQVTGGRNRIPQTVYVIGL--VQLCLLASARMFCTEKDKNWAIRTVALVSACS 691
             +  M   ++         V ++    +   L +      +                 S
Sbjct: 572 QGLPLMNQIISWATLASSLVVPLLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLS 631

Query: 692 SPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSIC 751
             + +    +   L    +     +  ++       +  +  +             L   
Sbjct: 632 CLMFVWINIEQETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTA 691

Query: 752 MFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLT 787
            FF +G+  + +     + +     F       L+ 
Sbjct: 692 -FFGTGNIASINSFDLASVYCFLTVFSPFMMGALMM 726
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  527 bits (1345), Expect = e-148
 Identities = 93/826 (11%), Positives = 200/826 (23%), Gaps = 126/826 (15%)

Query: 15  FLLIHAIAILIFTRGFLLTRTELPFHS-----TCSDVSL-SPCLASPRSNHDSSSEPKPW 68
            LL  A+ +LI    F  +  ++ F S          +   P                  
Sbjct: 1   MLLFFALGLLIH-FVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVI---IHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D   ++  +
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               + DL       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFG------------------ILVISL 478
           L   I  + N      +  +        + + TG                    +L + +
Sbjct: 461 L--IIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 479 ILQFL--AVFHGDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L       D   ++ ++  +     L +    + +   SF              ++
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LAT---TGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L             + +    +     +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L        L             +L + +L  VL + +  + +  + K   +  M   V
Sbjct: 628 LLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIV 687

Query: 644 TGGRNRIPQTVYVIGLVQL--CLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +           ++    L   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSL 747
              L    +     +  ++       +  +               L
Sbjct: 748 QETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLILL 793
 Score =  526 bits (1342), Expect = e-148
 Identities = 91/826 (11%), Positives = 196/826 (23%), Gaps = 123/826 (14%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSL-SPCLASPRSNHDSSSEPKPW 68
           L     LLIH +        +  +      H      +   P                  
Sbjct: 3   LFFALGLLIHFVFFASIFDIYFTSPLV---HGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVI---IHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA----------------ANEWMKHYVDVLCVNAWQ 378
             +  L ++     +S   N                           K   D   ++  +
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILR 403

Query: 379 VKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDR--NGDDGSTDISAL 436
             R    Y               + DL       +    +  L      G  G    ++L
Sbjct: 404 KARS---YIKQEKFDEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSL 460

Query: 437 LKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFG------------------ILVISL 478
           L   I  + N      +  +        + + TG                    +L + +
Sbjct: 461 L--IIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 479 ILQFL--AVFHGDKSYAVGSWLSTGAAFTLFI----VTIRACSFLSNSYILEEGKVANFL 532
               L       D   ++ ++  +     L +    + +   SF              ++
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFF-----------YRYM 567

Query: 533 LAT---TGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVS-IDIGLTKQAATSQFMSSSPSW 588
           L             + +    +     +     +L V  +   + ++   S  M +    
Sbjct: 568 LTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLV 627

Query: 589 MLGIAPDHPAL-----TYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLLQV 643
           +L        L             +L + +L  VL + +  + +  + K   +  M   V
Sbjct: 628 LLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHHSLLKKEGLPLMNQIV 687

Query: 644 TGGRNRIPQTVYVIGLVQL--CLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQ 701
           +           ++    L   L +      +                 S  + +    +
Sbjct: 688 SWATLASSLVAPLLSSTALSQRLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVE 747

Query: 702 GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSL 747
              L    +     +  ++       +  +               L
Sbjct: 748 QETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLILL 793
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  410 bits (1044), Expect = e-113
 Identities = 115/875 (13%), Positives = 231/875 (26%), Gaps = 133/875 (15%)

Query: 8   KKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHDSSSEPKP 67
            +L  LG L  H + +      + +T      H      +                 P  
Sbjct: 3   GRLLLLGILF-HVVFLKSIFDIYFVTPLI---HGMKQYSAGEAPAKRLFLIVGDGLRPDK 58

Query: 68  WMDK-------------LTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTF 114
            +                  L+++   N        +    PT S      L  G     
Sbjct: 59  LLQPHSEKVIGEEQTYAAPFLRSIIQNN---GTFGVSHTRVPTESRPGHVALIAGFYEDV 115

Query: 115 IDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ---------FQKSYPFP 165
             +   +    +  D+  NQ     +     G +    +F            F  S    
Sbjct: 116 SAVTKGWKKNPVNFDSVFNQS----RHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELE 171

Query: 166 SF-------NVKDLDTVDNGCIEHLFPT----LFKDDWDVLIAHFLGVDHAGHIFGVDSS 214
            F       +    D +D    + L       +   D  V   H LG+D  GH    DS 
Sbjct: 172 DFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSV 231

Query: 215 PMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETT 274
             +  ++  +  ++++++ + +          +  +   DHG +  G HG G  +   T 
Sbjct: 232 EYVENIQYIDGKIQELVDKMNNYY---NNDGASSWVFTADHGMSDFGSHGDGNLDNTRTP 288

Query: 275 MFAMSTKKHTTLV--PPEFDTSSCKQN----KDGKQMCISYIEQQHCQLCLGYPFLSEGA 328
           + A      +         D  S   N    K                + L +P  S G 
Sbjct: 289 IIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQ 348

Query: 329 FIGHVNPELYALGSSSWNLDKSDLGNFG-----------TQSAANEWMKHYVDVLCVNAW 377
                   L  L  SS    +  L N             ++   + + + Y  +      
Sbjct: 349 I------PLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEV 402

Query: 378 QVKRYIDVYSN--SSVVGFSSD-DMSRISDLYSAAEQNWSNSVKHILMDRNGDDGS---- 430
           Q   Y  V ++  S     + +        + S     +      +L+      G     
Sbjct: 403 QASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGL--RYLQRYDWLLLRSIVFFGYLSWI 460

Query: 431 -TDISALLKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFGI-----------LVISL 478
              I  +    I         V  + R         L+   F I           L  ++
Sbjct: 461 GYVICFVFSLNIEPSSKIVKPVSVVKR-VAFNIPFLLICIFFYIQSSPPFYYGYALFPTI 519

Query: 479 ILQFLAVFHGDKSYAVGSWL---STGAAFTLF-IVTIRACSFLSNSYILEEGKVANFLLA 534
            LQ +     +      ++L        F+L  I+ I  C      +I+      +    
Sbjct: 520 FLQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSY--FHREGF 577

Query: 535 TTGLI------KLRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFMSSSPSW 588
           +  L+       L ++    + +  +  +  +  +L     + + K+ +     +   + 
Sbjct: 578 SVILMGLAAWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAM 637

Query: 589 MLGIAPD-----HPALTYAIEIAP--ILSVVILICVLYVAIAKAPNEGVWKYVTVGSMLL 641
            +          + A  Y         L + +LI +  V +     + + + + +  +L 
Sbjct: 638 SVAGVFYILYRRNQAFQY-SSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILR 696

Query: 642 QVTGGRNRIPQTVYVIGLVQL---------CLLASARMFCTEKDKNWAIRTVALVSACSS 692
            V  G   +  T Y+I    +          L      F                     
Sbjct: 697 LVAFG---LFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFI 753

Query: 693 PIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWSLLSICM 752
            + L    +  +              L     R K D +   S  +    + + +     
Sbjct: 754 TLGLWMELETELQKYTEQ--------LHPEYSRKK-DAKFHLSLSHIRISLFFYIFINVA 804

Query: 753 FFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLT 787
           FF +G+  +       +       F  + Q  LL 
Sbjct: 805 FFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLM 839
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  409 bits (1042), Expect = e-113
 Identities = 115/861 (13%), Positives = 236/861 (27%), Gaps = 142/861 (16%)

Query: 2   ETYLKNKKLT-ALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHD 60
             +LK ++    +  + +HA+ +L     +      +            P          
Sbjct: 36  RRWLKRRETWLVVLGVALHAVYMLSIFDIYF-KTPIVHGMDPVPPRFSEPPAKRLVLLIS 94

Query: 61  SSSEPKPWMDK-------LTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPT 113
                  + +           L+ +        +   + A PPT S      +  G    
Sbjct: 95  DGLRADKFFEPDEEGKYRAPFLRNIIKN---QGRWGVSHARPPTESRPGHVAIIAGFYED 151

Query: 114 FIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLF------------PNQFQKS 161
              +   + A  +  D+  NQ     +     G      +F            P++++  
Sbjct: 152 PSAVTKGWKANPVEFDSVFNQS----RHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDF 207

Query: 162 YPFPSF-NVKDLDTVDNGCIEH----LFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPM 216
               SF +    D  +              L   D  V+  H LG D  GH     SS  
Sbjct: 208 ATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIY 267

Query: 217 INKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMF 276
           +N ++  + + E+V ++LE           T  I   DHG +  G HG G     +T + 
Sbjct: 268 LNNVKVVDKIAERVYHLLEDYYR----DNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLV 323

Query: 277 AMSTKKHTTLVPPEFDTS------------SCKQNKDG--------KQMCISYIEQQHCQ 316
           A                S                  D                       
Sbjct: 324 AWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTL 383

Query: 317 LCLGYPFLSEG-AFIGHVN----PELYALGSSSWNLDKSDLGNFGTQSAANEWMKHYVDV 371
           L L  P  S G   +G++      E+ A+ +++  +    L     +S+ + + K +  +
Sbjct: 384 LGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPL 443

Query: 372 LC--VNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILM---DRNG 426
           +    +  Q+   I   S  + +  + D    + +L S    ++  +   +++      G
Sbjct: 444 VHHSFSLSQIDELISAKSYEAAMKLAVD----LRNL-SLEGLHYFQTYDWLMLMTVITLG 498

Query: 427 DDGSTDISAL-----LKEQIAEYLN------FFSSVVELARSKW-----TEFNLNLMITG 470
             G   + AL           +         + S  + +A             L     G
Sbjct: 499 YTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIG 558

Query: 471 FGILVISLILQFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACS-----FLSNSYILEE 525
             +     +   +   +              A + + ++   A +      L +S+   +
Sbjct: 559 MTV----FLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERK 614

Query: 526 GKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFMS-- 583
                FL+A      L +  +        F+ ++  F+   ++     +    +  +S  
Sbjct: 615 LYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPA--EIPDNNNLVSPF 672

Query: 584 ------SSPSWMLGIAPD-----------------HPALTYAIEIAPILSVV-------I 613
                     W +                         L      A   S +       I
Sbjct: 673 LGANDTDIFGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVFYSALAVVLMAWI 732

Query: 614 LICVLYVAIAKAPNEGVW-----KYVTVGSMLLQVTGGRNRIPQTVYVIGLVQLCLLASA 668
           L        +K     +      +++T+GS    +     RIP     + L  +    + 
Sbjct: 733 LFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLV--FMVLFNVAFFGTG 790

Query: 669 RMFCTEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKS 728
                   +  ++     + +      LL  K      LV + A   I +L  V R    
Sbjct: 791 NFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLV-ICAFSAITKLVRVPRLGCY 849

Query: 729 DGQSKFSKLNPLCVVQWSLLS 749
                FS    +  + +  L 
Sbjct: 850 FLVILFSD---IMTIHFFFLV 867
 Score = 71.1 bits (173), Expect = 8e-11
 Identities = 38/408 (9%), Positives = 90/408 (21%), Gaps = 117/408 (28%)

Query: 410 EQ------------------------------------------------NWSNSVKHIL 421
                                                             ++  +   ++
Sbjct: 431 SSNSLFFKPFKPLVHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLM 490

Query: 422 M---DRNGDDGSTDISAL-----LKEQIAEYLN------FFSSVVELARSKW-----TEF 462
           +      G  G   + AL           +         + S  + +A            
Sbjct: 491 LMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSP 550

Query: 463 NLNLMITGFGILVISLILQFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACS-----FL 517
            L     G  +     +   +   +              A + + ++   A +      L
Sbjct: 551 PLYHAYIGMTV----FLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELL 606

Query: 518 SNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAA 577
            +S+   +     FL+A      L +  +        F+ ++  F+   ++     +   
Sbjct: 607 VHSFTERKLYTWFFLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPA--EIPD 664

Query: 578 TSQFMS--------SSPSWMLGIAPD-----------------HPALTYAIEIAPILSVV 612
            +  +S            W +                         L      A   S +
Sbjct: 665 NNNLVSPFLGANDTDIFGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVFYSAL 724

Query: 613 -------ILICVLYVAIAKAPNEGVW-----KYVTVGSMLLQVTGGRNRIPQTVYVIGLV 660
                  IL        +K     +      +++T+GS    +     RIP     + L 
Sbjct: 725 AVVLMAWILFENASHHSSKVKESSLSENNTEEHITIGSDERYLQLSDVRIPLV--FMVLF 782

Query: 661 QLCLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALV 708
            +    +         +  ++     + +      LL  K      LV
Sbjct: 783 NVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLV 830
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  394 bits (1002), Expect = e-108
 Identities = 96/824 (11%), Positives = 193/824 (22%), Gaps = 122/824 (14%)

Query: 11  TALGFLLIHAIAILIFTRGFL--LTRTELPFHSTCSDVSLSPCLASPRSNHDSSSEPK-P 67
                L++H + +      +      T L          L P                  
Sbjct: 2   WIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSF 61

Query: 68  WMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIV 127
           + +    +  L         +  +    PT +      L  G       +   + +  I 
Sbjct: 62  FEENCRYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPID 121

Query: 128 EDNFINQLVL-----NGKRLVMM-----GDDTWTQLFPNQFQKSYPFPSF--NVKDLDTV 175
            D   N+            L +      G +   + + +    S  + ++  +      V
Sbjct: 122 FDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKRV 181

Query: 176 DNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILE 235
               ++     L +    V   H LG+D AGH+    +      LE+    +  +    E
Sbjct: 182 -KLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIYQEFE 240

Query: 236 SQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSS 295
                    + T  ++  DHG T +G                 S              + 
Sbjct: 241 ----RVFPDKRTAYLLTADHGMTDSG----------------ASRAVPKPGGRTFMPNNE 280

Query: 296 CKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNF 355
                  +             L L  P  + G         L  L  S      +   N 
Sbjct: 281 GPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKL------PLGYLNVSKEYEAMAAHVNA 334

Query: 356 GT----------QSAANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDL 405
                       Q     +    ++   +NA  +KRY D           S  + +   +
Sbjct: 335 LQLLEQYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKREYSLCIDKSQVI 394

Query: 406 YSAA---EQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFSSVVELARSKWTEF 462
            S A      +    + +L+          +  + +                      E 
Sbjct: 395 MSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSR--------NRASKVELVLER 446

Query: 463 NLNLMITGFGILVISLILQFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYI 522
           +  ++       VI LI+  L+         +  +L       L  +     +F S+   
Sbjct: 447 SNKIVRVSIVSSVIVLIICLLS---QGTPLDISFYLLLPYFVWLKALQPWNINFSSSP-- 501

Query: 523 LEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFM 582
                      A+   +    + M +            V ++  +  +       T    
Sbjct: 502 -----------ASAYSVPALQTSMWQL-----------VLLIACAELMVF-----TFFER 534

Query: 583 SSSPSWMLGIAPDHPALTYAIEIAPILS----VVILICVLYVAIAKAPNEGVWKYVTVGS 638
                     A  +    +  +     S    V+IL C   + ++     G      V  
Sbjct: 535 RLIALCFCVFACYNSWENFQWKSRDFFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIV 594

Query: 639 MLLQVTGG-------RNRIPQTVYVIGLVQLCL-------------LASARMFCTEKDKN 678
           +              RN    +  +I L  +               L  A          
Sbjct: 595 IFTNSFWNSKSRLCYRNHTKYSNALILLQTILCAYLHSNGINIPIPLKLASWLYLVYAFA 654

Query: 679 WAIRTVALVSACSSPII-LLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKL 737
             + +           I    G   + L   Y      ++ +E          +++ S L
Sbjct: 655 SILLSKESRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNISLRAQSARAERSVL 714

Query: 738 NPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIR 781
                +          F SG+  +        A      F    
Sbjct: 715 RLAFTLLLYTF--FSLFGSGNIASISSFDPNIARCYLSHFAPFV 756
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  393 bits (1000), Expect = e-108
 Identities = 75/610 (12%), Positives = 163/610 (26%), Gaps = 94/610 (15%)

Query: 11  TALGFLLIHAIAILIFTRGFLLTRT--ELPFHSTCSDVSLSPCLASPRSNHDSSSEP-KP 67
            ++  L++H + +      +  +    +L   ST  ++ L P                  
Sbjct: 2   WSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSV 61

Query: 68  WMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIV 127
             D  + +  L       A +  + A PPT +      +  G          +    A +
Sbjct: 62  LADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGG---------FNEDPAATL 112

Query: 128 EDNFINQLVLNGKRLVMMGDDTWT-----QLFPNQFQ-----KSYPFPSFNVKDLDTVDN 177
             N      +  +    +G   W      ++F +        +   F   ++ D   +D 
Sbjct: 113 TWNPSTFDSVFNRSRNAIG---WMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQ 169

Query: 178 GCIEHLFPTLFKDD---------WDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLE 228
              + +   +  +            +   +   +D A H+   +S     KL      + 
Sbjct: 170 WTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIR 229

Query: 229 KVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVP 288
           +   + ES          T  ++  D+G +L   HGGG    VET           +   
Sbjct: 230 QTYELFES----VFNDSRTAYLMTADYGISL---HGGGGERGVETPFILWGAGVKRSAPN 282

Query: 289 PEFDT---SSCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGA-FIGHVNPELYALGSSS 344
           P  +     +       +   I         + L  P  +     +G +N  +       
Sbjct: 283 PGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVL 342

Query: 345 WNLDKSDLGNF---GTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSR 401
                  L        +               + + +++ Y  +           + +  
Sbjct: 343 HLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKV 402

Query: 402 ISDLYSAAE---QNWSNSVKHILMDRNGDDGSTDISALLKEQIAE----------YLNFF 448
              +   A+   + +       L+             LL     E          YL + 
Sbjct: 403 SHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYLTW- 461

Query: 449 SSVVELARSKWTEFNLNLMI----TGFGILVISLILQFLAVFH-----GDKSYAVGSWLS 499
            + + +         L ++          L++   +  LA+        D          
Sbjct: 462 -TTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDRDLMCQFPVLHL 520

Query: 500 TGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRK-----EA 554
            G      ++ + A     NS+I              GL+ L    +           + 
Sbjct: 521 VGIVMPGVLLILMA---FHNSHI--------------GLLYLPIVCLNNRRAFFRPSLKL 563

Query: 555 FMFLAMVFVL 564
             +LA+VF+L
Sbjct: 564 IFWLALVFLL 573
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  393 bits (1000), Expect = e-108
 Identities = 158/591 (26%), Positives = 246/591 (40%), Gaps = 103/591 (17%)

Query: 14  GFLLIHAIAILI-----FTRGFLLTRTELPFHSTCSDVSLSPCL---------------- 52
            F+LI    ++      F+RGFLL R      STC  +S +P                  
Sbjct: 6   LFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIFKDV 65

Query: 53  -----------ASPRSNHDSSS------------EPKPWMDKLTILQTLAFANDSSAKIF 89
                      +        +             +P P+ +KL +LQ L   N   A++ 
Sbjct: 66  NASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLM 125

Query: 90  KAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDT 149
           +  ADPPTT+LQRLKGLTTG LPTFIDIG++F +P I EDN I+Q+V N   +V +GD T
Sbjct: 126 RFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDST 185

Query: 150 WTQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIF 209
           WT L+P++F++SY +PSF++ DLD+VDN  ++HL   L   DW VL+AHFLGVDH GH  
Sbjct: 186 WTDLYPHRFKRSYSYPSFDIFDLDSVDNEILKHLPKELESKDWQVLVAHFLGVDHCGHKH 245

Query: 210 GVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAE 269
           G     M  KL + N V+  V+  +           +T L+VMGDHG T +GDHGG T +
Sbjct: 246 GPMHEEMARKLGEMNEVIRSVVAAM---------DNDTTLLVMGDHGMTASGDHGGDTDD 296

Query: 270 EVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAF 329
           E    +FA S K+H          S            I  +      L +  P+ + G  
Sbjct: 297 ETNALLFAYS-KQHRFYGNDSGSDSEM-------LQQIDLVPTLATILGVPIPYSNLGLV 348

Query: 330 IGHVNPELYALGSSSWNLDKSDLGNFGTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNS 389
             ++ P+L           +    N       + W          NA Q+ RY   Y+  
Sbjct: 349 NFNIVPDL-----------RVPHLNKFQTLLLHSWQ---------NAQQIYRYFFQYALE 388

Query: 390 SVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFS 449
           +   F+ + M  +               + IL+         ++    K  + +      
Sbjct: 389 NKRTFNVEQMDHLET-------------EFILLTHRVQTVYNEV--AFKSFVRDLNTNLR 433

Query: 450 SVVELARSKWTEFNLNLMITGFGILVISLILQFLAVFHGDKSYAVGSWLSTGAAFTLFIV 509
            ++   R  W  F+   M  G  +     +     V +  +             F ++++
Sbjct: 434 DILGTCREIWVRFDPTQMSQG-LLFTFLPLFFIFLVVNNSRPADFPHIFKAKEVFYVYLI 492

Query: 510 TIRACSFL-----SNSYILEEGKVANFLLATTGLIKLRYSVM-RKTMRKEA 554
            + A  F      + S+  EE  V  F   ++ +I   +++    ++    
Sbjct: 493 NLAAGVFGYRYFKTFSFKTEEQGVIFFTAISSAVILAFHTLRHWTSIATNW 543
 Score =  114 bits (285), Expect = 6e-24
 Identities = 28/139 (20%), Positives = 52/139 (37%), Gaps = 14/139 (10%)

Query: 674 EKDKNWAIRTVALV---------SACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVER 724
            +     +  +A V            +  +I+L   + S+  +V +  G  ++ +  + R
Sbjct: 795 RRSHIPVVYGLATVYSSIVIAFGVFLALVMIVLLEPRASIGLVVCVAVGAILLSVHSILR 854

Query: 725 -RTKSDGQSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEF---VLI 780
            RT +  +S         +V W LL+   FFA+ H      + + AAFVG         +
Sbjct: 855 YRTATSFESCVQPTFT-ALVGWFLLAHFCFFATSHQTTLSQIEWRAAFVGRTTGIGQSNL 913

Query: 781 RQAILLTIETFGFSIILSV 799
               L+ + TF   I    
Sbjct: 914 VSGALVILNTFCGPIFFFC 932
 Score = 77.0 bits (188), Expect = 1e-12
 Identities = 15/56 (26%), Positives = 31/56 (54%)

Query: 824  FQMYMLFGVISATTVTATILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLA 879
            F++   F ++    +   +L  TI  RHLMVW +FAP+F+++ +   ++   + + 
Sbjct: 998  FKLATQFFMLQGLKIFCAMLACTIHCRHLMVWKIFAPRFIYEALATFVSLPALIVG 1053
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  381 bits (971), Expect = e-104
 Identities = 167/498 (33%), Positives = 233/498 (46%), Gaps = 85/498 (17%)

Query: 8   KKLTALGFL----LIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPC------------ 51
           +K++ L FL     +    I +FT GFLLTR EL   S+C ++                 
Sbjct: 10  RKVSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGAC 69

Query: 52  -----LASPRSNHDSSSEPKP-----------------WMDKLTILQTLAFANDSSAKIF 89
                 +        +                      ++ KL  LQ +  +     +++
Sbjct: 70  WMPSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLY 129

Query: 90  KAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDT 149
           ++  DPPTT++QRLK LTTG LPTFID G++F + AIVEDN I QL   G+R+V MGDDT
Sbjct: 130 RSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGDDT 189

Query: 150 WTQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIF 209
           W  LFP  F +++ F SFNV+DL TVDNG +EHL+PTL    WDVLIAHFLGVDH GH  
Sbjct: 190 WRDLFPGAFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDGGSWDVLIAHFLGVDHCGHKH 249

Query: 210 GVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAE 269
           G     M  KL Q + V++ +I  LE+         +T+L+V GDHG T+NGDHGG +  
Sbjct: 250 GPHHPEMAKKLSQMDQVIQGLIERLEN---------DTLLVVAGDHGMTMNGDHGGDSEL 300

Query: 270 EVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAF 329
           EV   +F  S       VPPE +              +S +      L L  PF + G  
Sbjct: 301 EVSAALFLYSPTALFPSVPPE-EPEVIP--------QVSLVPTLALLLGLPIPFGNTG-- 349

Query: 330 IGHVNPELYALGSSSWNLDKSDLGNFGTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNS 389
              V  EL++ GS S +       +   Q +A          L +NA QV R++  YS +
Sbjct: 350 --EVMAELFSGGSDSSH----PHSSALAQVSA----------LHINAQQVSRFLHTYS-A 392

Query: 390 SVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFS 449
           +       ++ R+  L+S A   +    +H L D        +  A L    AE+  F  
Sbjct: 393 ATQDLQVKELHRLQTLFSKASARY----QHFLRDP------QEAEAALSTLTAEFQQFLR 442

Query: 450 SVVELARSKWTEFNLNLM 467
               L    W  F+L  M
Sbjct: 443 GARALCIESWARFSLVRM 460
 Score =  163 bits (411), Expect = 9e-39
 Identities = 56/241 (23%), Positives = 90/241 (37%), Gaps = 41/241 (17%)

Query: 681  IRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPL 740
            + + A+V+A       L       ++LV+L+       L        +   +        
Sbjct: 840  VYSAAMVTALLLLAFPLMLLHVERVSLVFLLLFL-QSFLLLHLLAAGTPVATPGPFTVLW 898

Query: 741  CVV-QWSLLSICMFFASGHWCAFDGLRYGAAFVGFDE--FVLIRQAILLT-IETFGFSII 796
              V  W LL+   F+++GH   F  + + AAFVGF +          LL    TF   ++
Sbjct: 899  QAVSAWVLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLL 958

Query: 797  LSVFGLPLLIP---------FHSQT-PQAHGEKR-------------------------- 820
             +V    LL+             Q  P +  E R                          
Sbjct: 959  FAVGCPLLLLWPFLCERQGPKRRQPLPGSESEARVRPEEEEELQEPLMEVRLRDAPNHFN 1018

Query: 821  HQLFQMYMLFGVISATTVTATILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLAS 880
              L Q+ + +  I    + A  L  +I RRHLMVW +FAPKF+F+ V  I++ + + L  
Sbjct: 1019 AALLQLGLKYLFILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGI 1078

Query: 881  A 881
            A
Sbjct: 1079 A 1079
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  378 bits (962), Expect = e-103
 Identities = 53/386 (13%), Positives = 100/386 (25%), Gaps = 57/386 (14%)

Query: 15  FLLIHAIAILIFTRGFLLTRTELPFHS-----TCSDVSL-SPCLASPRSNHDSSSEPKPW 68
            LL  A+ +LI    F  +  ++ F S          +   P                  
Sbjct: 1   MLLFFALGLLIH-FVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA 360
             +  L ++     +S   N      
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILE 369
 Score =  376 bits (958), Expect = e-103
 Identities = 51/386 (13%), Positives = 96/386 (24%), Gaps = 54/386 (13%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSL-SPCLASPRSNHDSSSEPKPW 68
           L     LLIH +        +  +      H      +   P                  
Sbjct: 3   LFFALGLLIHFVFFASIFDIYFTSPLV---HGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ-----NKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVN 334
                 +   ++D    K+      K                + + +P  S G       
Sbjct: 290 IKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGIL----- 344

Query: 335 PELYALGSSSWNLDKSDLGNFGTQSA 360
             +  L ++     +S   N      
Sbjct: 345 -PVGYLNNTGLFKAESMFTNAVQILE 369
>sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CHROMOSOME I
 pir||S62432 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 pir||T37638 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91096.1| (Z54308) putative major facilitator superfamily protein
           [Schizosaccharomyces pombe]
          Length = 758

 Score =  357 bits (907), Expect = 6e-97
 Identities = 90/440 (20%), Positives = 167/440 (37%), Gaps = 34/440 (7%)

Query: 9   KLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHDSSSEPKPW 68
           +    G   +     ++F  GF   + +    +  +  S    +         +      
Sbjct: 2   RFAFFGIFWLQIFGSILFLLGFFPHKNDSTGKAMSNQFSPPAVIDQVVFVMVDALRADFV 61

Query: 69  MDK---LTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFG--- 122
             K   +   Q+L + +      F AFA  PT ++ RLK LTTG +P F+D+  +     
Sbjct: 62  FSKSHNMPFTQSLLYNSTH-GIGFSAFARSPTVTMPRLKALTTGTIPGFLDVLLNIAESD 120

Query: 123 --APAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCI 180
             +    +D+++ QL    K++   GDDTW +LFP+ F K     SF V D   VDN   
Sbjct: 121 TGSSIEAQDSWVYQLNSFNKKIEFYGDDTWLKLFPSAFSKFEGTTSFFVSDYTEVDNNVT 180

Query: 181 E---HLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQ 237
               H  P+     WD LI H+LGVDH GH++G  S  +  KL + ++++ ++   L+  
Sbjct: 181 RNFDHALPSSLSHSWDALILHYLGVDHIGHLYGPSSPLLNIKLLEIDTIISRIYKYLQEY 240

Query: 238 AGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTM-FAMSTKKHTTLVPPEFDTSSC 296
                 H   ++++ GDHG    G+HGG ++ E    +     + + + +  P  +    
Sbjct: 241 DEKTNTHS--LIVLCGDHGMNEVGNHGGSSSGETTAALSLLFPSNELSHINKPILNMDDN 298

Query: 297 KQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFG 356
             +   +   +  +      L +  P  + G     V   +  L   +     + L N  
Sbjct: 299 PYSILERVEQVDVVPTICLLLGIPIPKGNMGK----VLSPVTELWKDTKTAKMAALSNLF 354

Query: 357 TQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNS 416
             S          ++               S+ + +  +      + +L S      S+ 
Sbjct: 355 QLSLLKNPSLTTSEL---------STQFQDSDLNDIRLA------LENLQSQMVAQSSSY 399

Query: 417 VKHILMDRNGDDGSTDISAL 436
               ++      G+  I +L
Sbjct: 400 SLDRMLVAISILGACSILSL 419
 Score =  258 bits (654), Expect = 3e-67
 Identities = 69/446 (15%), Positives = 138/446 (30%), Gaps = 88/446 (19%)

Query: 438 KEQIAEYLNFFSSV------------VELARSKWTEFNLNLMITGFGILVISLILQFLAV 485
               +E    F                    ++ + ++L+ M+    IL    IL  +  
Sbjct: 363 SLTTSELSTQFQDSDLNDIRLALENLQSQMVAQSSSYSLDRMLVAISILGACSILSLILF 422

Query: 486 FHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSV 545
            +      + ++    A     +  I      S+S+I EE  +  F   +  L++L    
Sbjct: 423 RN------LYNYKELLAFAPFVVQNI--IIVFSSSFIEEEHVIWYFAAVSLSLLQLLNPK 474

Query: 546 MRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALTYAIEI 605
            R          LA    L     I    Q           S +  I  D  A +  ++ 
Sbjct: 475 TR----------LAGSLQLFCLSIIKRWNQTG------QKYSDLRDIVDDFIAPSTFMKT 518

Query: 606 APILSVVILICVLYVAIAKAPNEGVW---KYVTVGSMLLQVTGGRNRIPQTVYVIGLVQL 662
                 ++ +   ++   ++P+   +    ++    ++  ++   N +P    +I     
Sbjct: 519 ------ILCVTSAFMPAIRSPSPINFLSSMFIAFYKLMPIISKHLNELP----IIASFDY 568

Query: 663 CLLASARMFCTEKDKNWAIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGV 722
                             I ++ L+S  S P       Q S+  L+       + RLE +
Sbjct: 569 TFFV------------RIIWSLLLISFLSKPTFKQLRCQLSLFILL-------LTRLENM 609

Query: 723 ERRTKSDG-QSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIR 781
                 D  Q    +   L  V + +     FF+ G+  +   +    A+ G D + +  
Sbjct: 610 GLYLLYDIWQRTMPEEGTLASVMYYVAEQVAFFSLGNSNSLATVDLSQAYTGLDSYNIFA 669

Query: 782 QAILLTIETFGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTAT 841
             ILL    F    +      P  +   S                 +    I ++     
Sbjct: 670 VGILLFTSVF-AGALWWCLHQPKRMMDRS-----------------VKTFWIMSSISLTF 711

Query: 842 ILC-VTIQRRHLMVWGLFAPKFVFDV 866
           +     I R HL VW +F+PK +++ 
Sbjct: 712 LCISCFIMRHHLFVWSVFSPKLLYNA 737
>gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster]
          Length = 608

 Score =  339 bits (861), Expect = 1e-91
 Identities = 72/525 (13%), Positives = 149/525 (27%), Gaps = 79/525 (15%)

Query: 391 VVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFSS 450
                 D +       S       N   H L           I  L+   IA YL     
Sbjct: 124 TEQLQLDGLKVGQLWLSVIAAVVLNYTSHALDIIMTSSTLYSILLLVPISIAVYLTI--- 180

Query: 451 VVELARSKWTEFNLNLMITGFGI-LVISLILQFLAVFHGDKSYAVGSWLSTGAAFTLFIV 509
            V  A  K     L        I L + L+  +                           
Sbjct: 181 DVAQALLKIALPPLYTRRLKISIPLPLPLLACY--------------------------- 213

Query: 510 TIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVSID 569
            IR  +  S+S+I  E     +L  T  L+    ++  +  +    +    ++ +  +  
Sbjct: 214 AIRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTIASTCL 273

Query: 570 IGLTKQAATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLY----VAIAKA 625
             + K       ++               L        I S+++L   L+    +  + A
Sbjct: 274 WQMRKVLVVLMLLTLMR--------YIHRLQAIRSTVVIFSMLLLWARLHRHSQLPQSLA 325

Query: 626 PNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIG---LVQLCLLASARMFCTEKDKNWAIR 682
               ++       +  QV            ++    ++  C LA   M            
Sbjct: 326 SGAALFMVYCFRGLNGQVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYR-AALPQAH 384

Query: 683 TVALV--------------SACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKS 728
           +   V              ++      LL      +L  V LVA     +L  V     +
Sbjct: 385 SFGKVPPTGALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVY---GT 441

Query: 729 DGQSKFSKLN-PLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLT 787
             +    +L     ++    L+   FF  G+  +   +     ++G   +     AI +T
Sbjct: 442 SARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVT 501

Query: 788 IETFGFSIILSVFGLPLLIPFHSQ---------TPQAHGEKRHQLFQMYMLFGVISATTV 838
           + T+   I   ++ +   +    +               +          L+  +     
Sbjct: 502 LNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAP-----LYAALIMLPA 556

Query: 839 TATILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASAYY 883
              +  +   R HL ++ +F+PK ++D   +++  L+  + S Y+
Sbjct: 557 AFYLCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLVTSLYF 601
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  335 bits (852), Expect = 2e-90
 Identities = 79/489 (16%), Positives = 161/489 (32%), Gaps = 52/489 (10%)

Query: 400 SRISDLYSAAEQNWSNSVK-HILMDRNGDDGSTDISALLKEQIAEYLNFFSSVVELARSK 458
             +  L +       N +    L D +G+    D +A       +      ++ E     
Sbjct: 345 DFLQLLPNKLASMKENFMHLWKLSDHHGEVALDDFTA------EDIYTKMYTIQETLTKS 398

Query: 459 WTEFNLNLMITGFGILVISLILQFLAVFHGDKSYAVGSW--LSTGAAFTLFIVTIRACSF 516
            T +N  L+   F    +  ++  +   +    Y+   +  L   +   L +  I   S 
Sbjct: 399 ATNYNYPLLTLAF----VGFLIITIIAIYVLLRYSGPDFWQLRVSSLSVLLVSIILGVST 454

Query: 517 LSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQA 576
            ++S+I EE ++  +++     + L    +   +    F+ +A V  ++   + G  ++ 
Sbjct: 455 FASSFIEEEHQLWWWIVTAFSAVPLFVYRLNVLIIVRWFIMMACVRSIKFWNNSG--QKF 512

Query: 577 ATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYVTV 636
             S  MS+  +        +P+  + + +   L +++      V         V    T 
Sbjct: 513 IYSNVMSNLLNQ-------NPSWKWCLNMLTFLVLIMASAGFQVLHFIVTTILVGLCFTY 565

Query: 637 GSMLLQVTGGRNRIPQTVYVIGL------VQLCLLASARMFCTEKDKNWAIRTVALVSAC 690
                 V G +  IP  ++ +         +  L+  AR+F          R V      
Sbjct: 566 KISWEIVNGNQAEIPLFMHDLLAKIDFAPTESNLIVLARVFFQAWAIVVISRLVLTKLKV 625

Query: 691 S-----------SPIILLSGK---QGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSK 736
                          ILL  +   Q     LV+ +    I               SK   
Sbjct: 626 LNKNYLIKDMKVYITILLMFQTSSQNIGQFLVFQILESQIFYFFQNIPTASLTSTSKIYF 685

Query: 737 LNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVG-FDEFVLIRQAILLTIETFGFSI 795
            N + ++    L    FF  G   +   +  G A+ G   ++ +    IL+++  F  +I
Sbjct: 686 SNLVSLI----LQNFTFFQFGGTNSISTIDLGNAYHGVSSDYNIYVVGILMSVANFAPAI 741

Query: 796 ILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTATILCVTIQRRHLMVW 855
                 LP  I + S   Q   +   +       +  I  T +   +    + R HL +W
Sbjct: 742 YW--SMLPWSINYASIPAQVKLQTFIRSKLPAFTYHCIFGTCL---MTACVVLRFHLFIW 796

Query: 856 GLFAPKFVF 864
            +F+PK  +
Sbjct: 797 SVFSPKLCY 805
 Score =  321 bits (815), Expect = 3e-86
 Identities = 99/394 (25%), Positives = 153/394 (38%), Gaps = 41/394 (10%)

Query: 19  HAIAILIFTRGFLLTRTELPFHSTC-----SDVSLSPCLASPRSNHDSSSEPKPWMD--- 70
             +AIL+F   F   +  L   S        D+               +       D   
Sbjct: 13  QLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSDFLFDSQI 72

Query: 71  -KLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF----GAPA 125
                +      N   A  + +FA+PPT +L RLK +TTG  P+FID+  +      +  
Sbjct: 73  SHFNNVHQWL--NTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQDIDSND 130

Query: 126 IVE-DNFINQLVLNGKRLVMMGDDTWTQLFPNQ-FQKSYPFPSFNVKDLDTVDNGCIEHL 183
           + E D+++ Q + +   +  MGDDTW +LFP Q F  + P  SF V D   VDN    +L
Sbjct: 131 LSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVDNNVTRNL 190

Query: 184 FPTLFKD--DWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINI-LESQAGP 240
              LF++   WDV I H+LG+DH GH  G  S  M  K ++ +S+L+ + +  LE +   
Sbjct: 191 PGKLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSILKSIYDEVLEHED-- 248

Query: 241 GGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQN- 299
               ++T++ V+GDHG    G+HGG +A E    +  +S K      P      +   N 
Sbjct: 249 ---DDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARPESQVNYTLPINA 305

Query: 300 -------KDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDL 352
                         I  +        +  P  S G  I      L        N   S  
Sbjct: 306 SPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLP-------NKLASMK 358

Query: 353 GNFGTQSAANEWMKHYVDVLCVNAWQVKRYIDVY 386
            NF      ++     V +    A  +   +   
Sbjct: 359 ENFMHLWKLSDHHGE-VALDDFTAEDIYTKMYTI 391
>ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis elegans]
 pir||T21487 hypothetical protein F28C6.4 - Caenorhabditis elegans
 emb|CAA92675.1| (Z68315) Similarity to Yeast hypothetical protein YJ10
           (SW:YJ10_YEAST)~cDNA EST yk160e12.5 comes from this
           gene~cDNA EST yk160e12.3 comes from this gene~cDNA EST
           yk317h4.3 comes from this gene~cDNA EST yk317h4.5 comes
           from this gene [Caenorhabditis ele>
          Length = 795

 Score =  327 bits (831), Expect = 5e-88
 Identities = 85/439 (19%), Positives = 160/439 (36%), Gaps = 72/439 (16%)

Query: 443 EYLNFFSSVVELARSKWTEFNLNLMITGFGILVISLILQFLAVFHGDKSYAVGSWLSTGA 502
               +F +V        +E     +     +L+++L L             + +   + +
Sbjct: 426 ALKKWFLTVQSELIGSASEVPNKSLGVCVFLLLVALTLSM----------GLWNLHLSKS 475

Query: 503 AFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIK-LRYSVMRKTMRKEAFMFLAMV 561
            F +F++ I   ++ ++S I EE ++  +L +T   I+ LR   +      ++  FLA +
Sbjct: 476 DFFIFLINI---TYFASSLIEEEHEIWYYLGSTVVAIRALRNFKIWNKTEVKSIFFLAFL 532

Query: 562 FVLRVSIDIGLTKQ--AATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLY 619
             +  S      ++    +S    S  S  L   P++  L   +   PI  +VIL C L+
Sbjct: 533 HRIACSYTQSTRRRWIMDSSLLPPSIFSDTLDFQPNN--LNTILNEYPI--IVILTCSLF 588

Query: 620 VAIAKAPNEGVWKYVTVGSMLLQVTGGRNRIPQTVYVIGLVQLCLLASARMFCTEKDKNW 679
                      W Y    S    +      +P   + + L +L       M         
Sbjct: 589 -----------WMYGYKQSKFHII------LPMVSHFLRLFELTQFNEVLMHFIRLSILP 631

Query: 680 AIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNP 739
              +   V A   P             L+ +V    I+ L  +    K      FSKLN 
Sbjct: 632 ISYSTGSVLAGCLP------------LLLAIVPVSQILLLLVIYNMGKL-----FSKLN- 673

Query: 740 LCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIETFGFSIILSV 799
           L  V++  L +  FF +G+  +   L   +A+VG   +  I   + L + TF   I+   
Sbjct: 674 LGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFLC 733

Query: 800 FGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTATILCVTIQRRHLMVWGLFA 859
                                  L  +   +  IS+     +++C+ I + HL +W +++
Sbjct: 734 GC-------------NASSCTSLLNHL-FSYR-ISSMC--TSLICLYIFQNHLFIWSVYS 776

Query: 860 PKFVFDVVDLILTDLLICL 878
           PK V+D+  +I   L+  L
Sbjct: 777 PKVVYDMAHVIFFGLIGLL 795
 Score =  302 bits (766), Expect = 2e-80
 Identities = 89/333 (26%), Positives = 135/333 (39%), Gaps = 20/333 (6%)

Query: 6   KNKKLTALGFLLIHAIAILIFTRGFL-----LTRTELPFHSTCSDVSLSPCLASPRSNHD 60
           K  K      L++ A A+L+++   L         E  F     + S SP          
Sbjct: 54  KKGKFWISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSP---RLVFMVI 110

Query: 61  SSSEPKPW---MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDI 117
            +            ++  ++       SAK+F A+A  PT +L R+    TG LP+F  +
Sbjct: 111 DAFRLSFLTSSKSPMSFTKSEITKK--SAKLFDAYARMPTVTLPRITAYLTGTLPSFGTV 168

Query: 118 GNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDN 177
             +     +   N+I+++   GK++   GDDTW +L P  F+K     SF V D   VDN
Sbjct: 169 LTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDN 228

Query: 178 GCIEHLFPTL--FKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILE 235
               HL   L      WD LI H+LG+DH GH  G  SS +  KL++ + V+ ++   L+
Sbjct: 229 NVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLK 288

Query: 236 SQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSS 295
           S      + + + LIV GDHG T  G HGG + +E    +      +            S
Sbjct: 289 S---STSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQDDS 345

Query: 296 CKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGA 328
            KQ        I           +  P  S G 
Sbjct: 346 LKQPPR--IEQIDVSSTIFDVFNMPIPIESYGI 376
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  326 bits (829), Expect = 1e-87
 Identities = 107/398 (26%), Positives = 163/398 (40%), Gaps = 30/398 (7%)

Query: 8   KKLTALG--FLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHDSSSEP 65
            K   L    +++   A+L+F RGFL +R  LP ++    VS              +   
Sbjct: 3   WKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESR-VSTEAPFQKAIIMVVDAFRS 61

Query: 66  KPWMDKLTILQTLAFA-NDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFG-- 122
                  +    L    N   A  F A + PPT +L R+KGLTTG  P F+D   +    
Sbjct: 62  DFAFSDQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAES 121

Query: 123 ---APAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGC 179
              +    +D+++ Q   +G+++ M GDDTW +LFP  F       SF V D   VDN  
Sbjct: 122 DNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNV 181

Query: 180 IEHLFPTLFKD-DWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQA 238
             H+   L +  +WDVLI H+LG+DH GH  G +S  M  K ++ + + +K+ N      
Sbjct: 182 TRHIDTQLDQKTEWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYN------ 235

Query: 239 GPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQ 298
                 ++T+LI++GDHG    G+HGG +A E    M   S K  T  +    +TS    
Sbjct: 236 ---SCDDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPW 292

Query: 299 N----KDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNP--ELYALGSSSWNLDKSDL 352
                   +      +      L L  P  + G  +  +          +   N     +
Sbjct: 293 TDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMV 352

Query: 353 ----GNFGTQSAANEWMKHYVDVLCVNAWQVKRYIDVY 386
               G    +S A E  + Y D L  N      Y  +Y
Sbjct: 353 QILQGQASRESDAKEVYELY-DTLNSNPSVKDYYNFLY 389
 Score =  305 bits (775), Expect = 2e-81
 Identities = 77/516 (14%), Positives = 153/516 (28%), Gaps = 92/516 (17%)

Query: 432 DISALLKEQ-----IAEYLNFFSSVVELARSKWTEFNLNLMITGF------GILVISLIL 480
           ++  L         + +Y NF            + +N N M+ G        IL +++  
Sbjct: 367 EVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTILALTVFS 426

Query: 481 QFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLIK 540
                  G K               L I+ +   S   +S + EE ++  ++ +      
Sbjct: 427 ALTLAVQGLKRL------------YLIILLVYFISVFGSSTVEEEHQIWYWITSGWMAF- 473

Query: 541 LRYSVMRKTMRKEAFMFLAMVFVLRVSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPA-- 598
           L  S  R   +         V V  V + I   +            +W L    + P+  
Sbjct: 474 LYISGSRN--KFGDGFNWMFVQV-FVRMMISWNQTGQKFTKKDDIVTW-LSKDGNQPSLW 529

Query: 599 --------------LTYAIEIAPILSVVILICVLYVAIAKAPNEGVWKYV-TVGSMLLQV 643
                           Y           +L  +   A         W+    V + LL +
Sbjct: 530 ILILVTYGVAFNKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPLLYL 589

Query: 644 TGGRNRIPQTVYVIGLVQLCLLASARMFCTEK---------DKNWAIRTVALVSACSSPI 694
            G    + +      +  L   A + +              DK   IR +   +  +  +
Sbjct: 590 MGLPGTLNEVN--ARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLH--AFLTLFL 645

Query: 695 ILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVVQWS-------- 746
           I  S  Q   L +VY            +  R  ++    FS  +                
Sbjct: 646 ITQSRIQNIPLFMVY--------YFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLS 697

Query: 747 ----LLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIETFGFSIILSVFGL 802
               LL    FF+ G+  +   +    A+ G   + +    +L  +  +   +  S  GL
Sbjct: 698 VSTLLLEQVSFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGL 757

Query: 803 PLLIPFHSQTPQAHGEK-------------RHQLFQMYMLFGVISATTVTATILCVTIQR 849
             L+  H +                     +  L     +    S+  ++A ++     R
Sbjct: 758 SFLLEDHVRNAIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLR 817

Query: 850 RHLMVWGLFAPKFVFDVV-DLILTDLLICLASAYYL 884
            HL +W +F+PK ++  V  ++   L+  + S+ ++
Sbjct: 818 EHLFIWTVFSPKLLYQFVWTVLQFALVDVILSSIFV 853
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  316 bits (802), Expect = 1e-84
 Identities = 115/355 (32%), Positives = 173/355 (48%), Gaps = 31/355 (8%)

Query: 1   METYLKNKKLTALGFLL---IHAIAILIFTRGFLLTRTELPFHSTCSDVS-LSPCLASPR 56
           ++ + KN K   +  +    +  I+I  FTRGFLL+R  L   S+ ++ S L P      
Sbjct: 25  IKKFQKNHKFYIILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAV 84

Query: 57  SNHDSSSEPK---------------PWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQ 101
                +                      + L++  + A   D+S+ + K  ADPPTT+LQ
Sbjct: 85  ILVIDALRFDFAIPVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQ 144

Query: 102 RLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLF-PNQFQK 160
           RLKGLTTG LPTFID G++F    I EDNF+ QL L  K +   GDDTW  LF P     
Sbjct: 145 RLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSND 204

Query: 161 SYPFPSFNVKDLDTVDNGCIEHLFPTL-FKDDWDVLIAHFLGVDHAGHIFGVDSSPMINK 219
           S+P  S NV DLDTVDNG +++    L    +WDV+I H LG+DH GH +G D   M  K
Sbjct: 205 SFPLESLNVWDLDTVDNGVMDYFHDHLQQDKEWDVMIGHMLGIDHVGHKYGPDHFTMREK 264

Query: 220 LEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMS 279
             Q +  ++ ++           + ++T+L+++GDHG    G+HGG + +E+E+T+F  S
Sbjct: 265 QIQVDQFIDWILK---------SIDDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYS 315

Query: 280 TKKHTTLVPPEFDTS-SCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHV 333
            K     +    + +     +       I  +      +    PF + G  I  +
Sbjct: 316 KKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPIDEI 370
 Score =  198 bits (501), Expect = 3e-49
 Identities = 39/203 (19%), Positives = 79/203 (38%), Gaps = 7/203 (3%)

Query: 681  IRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPL 740
            I          + +I +      +  L Y +    ++ +  +    K        K N +
Sbjct: 807  IYGSEFFLLVINVLISILLFNKPLAQLSYFLMCNQLLSILEIIDLLKL-------KENII 859

Query: 741  CVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIETFGFSIILSVF 800
              +   LLS   FF +GH      +++   F+  ++       I + + TFG  I++S+ 
Sbjct: 860  GPIALGLLSYQHFFTTGHQATIPSVQWDIGFMLSEKVTFPFTQIAIILNTFGPHILVSLS 919

Query: 801  GLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTATILCVTIQRRHLMVWGLFAP 860
               L +               ++     +    +     ++ + VT  RRHLMVW +F P
Sbjct: 920  VALLTLWSQPPDVLKPQTLLGRIVSNCGILLTYNTILCLSSFIWVTHFRRHLMVWKIFCP 979

Query: 861  KFVFDVVDLILTDLLICLASAYY 883
            +F+F  + LI+T L++   +  +
Sbjct: 980  RFIFASLSLIVTQLVVTFGTIAF 1002
 Score = 36.1 bits (83), Expect = 2.6
 Identities = 15/50 (30%), Positives = 24/50 (48%)

Query: 510 TIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLA 559
            I A  F SNS+ + E ++  FLL+T G++ L   V     +    +  A
Sbjct: 564 IIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKRQSTTALLTA 613
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  308 bits (783), Expect = 2e-82
 Identities = 46/319 (14%), Positives = 85/319 (26%), Gaps = 46/319 (14%)

Query: 15  FLLIHAIAILIFTRGFLLTRTELPFHS-----TCSDVSL-SPCLASPRSNHDSSSEPKPW 68
            LL  A+ +LI    F  +  ++ F S          +   P                  
Sbjct: 1   MLLFFALGLLIH-FVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVESDSLFNE----RKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ 298
                 +   ++D    K 
Sbjct: 290 IKFPQNVSAQQYDDEFLKG 308
 Score =  307 bits (779), Expect = 6e-82
 Identities = 44/319 (13%), Positives = 81/319 (24%), Gaps = 43/319 (13%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSL-SPCLASPRSNHDSSSEPKPW 68
           L     LLIH +        +  +      H      +   P                  
Sbjct: 3   LFFALGLLIHFVFFASIFDIYFTSPLV---HGMTPQFTPLPPPAKRLVLFVADGLRADTL 59

Query: 69  -------MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
                    +   ++ +            +    PT S      L  G       +   +
Sbjct: 60  YELDEDGNSRAPFIRNVIM---HEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGW 116

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ--------FQKSYPFPSFNVKDLD 173
               +  D+  N+     K     G      +F           +        F   D  
Sbjct: 117 KENPVESDSLFNE----RKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDAT 172

Query: 174 TVDNGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLE 221
            +D    + +                  ++  V   H LG+D  GH     S    + ++
Sbjct: 173 KLDTWVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIK 232

Query: 222 QYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTK 281
           + +  ++++++I +   G       T  I   DHG T  G HG G   E  T        
Sbjct: 233 KVDDGVKEIVSIFKHFYGD---DGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAG 289

Query: 282 KHTT--LVPPEFDTSSCKQ 298
                 +   ++D    K 
Sbjct: 290 IKFPQNVSAQQYDDEFLKG 308
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  307 bits (779), Expect = 7e-82
 Identities = 61/373 (16%), Positives = 96/373 (25%), Gaps = 54/373 (14%)

Query: 7   NKKLTALGFLLIHAIAILIFTRGFLLTRTE--LPFHSTCSDVSLSPCLASPRSNHDSSSE 64
           + K        +H + I      +  +     +P     S                    
Sbjct: 2   SWKFLIASI-TVHLVLIYSIFDVYYTSPLVHGIPPQFINSQ---EAPAKRIFIISADGLR 57

Query: 65  PKPWM---DKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSF 121
              +    DK   L ++   N+       + +  PT S      +  G       +   +
Sbjct: 58  YDTFNKYPDKSPYLHSIM--NERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGW 115

Query: 122 GAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLF-----PNQFQKSYPFPSFNVKDLDTVD 176
               +  D+  N+         M G      LF        F  S     F  KD   +D
Sbjct: 116 KKNPVQFDSVFNRSS----YSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLD 171

Query: 177 NGCIEHLFPTLF------------KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYN 224
               EH    L             ++   +   H LG+D  GH     S   I+ ++  +
Sbjct: 172 KWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVD 231

Query: 225 SVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHT 284
           S +EKV    +           T  +   DHG T  G HG G+ +EV T   A       
Sbjct: 232 SGIEKV----QHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQ 287

Query: 285 TLVPPEFDTSSCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSS 344
                                 I         +    P  S G     +          S
Sbjct: 288 -------------GGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNS-----KGS 329

Query: 345 WNLDKSDLGNFGT 357
               K+   NF  
Sbjct: 330 SYEFKAIEANFKQ 342
>gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melanogaster]
 gb|AAL28155.1| (AY060607) GH02677p [Drosophila melanogaster]
          Length = 858

 Score =  302 bits (767), Expect = 1e-80
 Identities = 55/451 (12%), Positives = 106/451 (23%), Gaps = 60/451 (13%)

Query: 10  LTALGFLLIHAIAILIFTRGFLLTRT--ELPFHSTCSDVSLSPCLASPRSNHDSSSEPKP 67
           L     +L+H + ++   R F  +    +L    T  D+ + P                 
Sbjct: 3   LWKSKVVLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADT 62

Query: 68  WMDK----LTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGA 123
                      ++ +         +  +    PT +      L  G          +   
Sbjct: 63  LFSDNCSGAVYIRDIIL---RQGLVGISKTSVPTLTRSAEVALFAG---------FNPMP 110

Query: 124 PAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHL 183
             +   NF                          F K       ++ DL           
Sbjct: 111 SILPTSNFDTIFNR-----------------TLAFDKGAFLRFSHLSDLRR--RLTKRAC 151

Query: 184 FPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSP---MINKLEQYNSVLEKVINILESQAGP 240
              L+  +  V++ +   V       G  S        KL      +     ++E     
Sbjct: 152 LEKLWYANKLVMLVNLAEV-------GGASPLDIGFQMKLHNTQRNIRDAYELIE----A 200

Query: 241 GGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDT--SSCKQ 298
                 T  +    HG T  G HGGG+ EE E                   D   ++   
Sbjct: 201 TFNDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLNNGVG 260

Query: 299 NKDGKQMCISYIEQQHCQLCLGYPFLSEGA-FIGHVNPELYALGSSSWNLDKSDLGNF-- 355
            +  K   I         + L  P  +      G++         S        L     
Sbjct: 261 MQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLTQAKA 320

Query: 356 -GTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRI---SDLYSAAEQ 411
                    + K       ++  Q+  Y +   +   +G+ S  +        +   + +
Sbjct: 321 IIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKSLK 380

Query: 412 NWSNSVKHILMDRNGDDGSTDISALLKEQIA 442
            + N     L+              L +   
Sbjct: 381 FYHNYYHIPLVVTTVLALLGWQFYQLVKLSQ 411
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  264 bits (670), Expect = 4e-69
 Identities = 74/608 (12%), Positives = 165/608 (26%), Gaps = 78/608 (12%)

Query: 4   YLKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCS-DVSLSPCLASPRSNHDSS 62
           + K +       +L H   +      + ++      H       + +P            
Sbjct: 2   WNKTRTTLLAVGVLFHLFYLWSIFDIYFISPLV---HGMSPYQSTPTPPAKRLFLIVGDG 58

Query: 63  SEPKPWMDK------------LTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGG 110
                  DK               +++L   N   A    +    PT S      +  G 
Sbjct: 59  LRADTTFDKVTHPVSGKTEFLAPFIRSLVMNN---ATYGISHTRMPTESRPGHVAMIAGF 115

Query: 111 LPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQ---------FQKS 161
                 +   + +  +  D+F NQ           G      +F +          +   
Sbjct: 116 YEDVSAVTKGWKSNPVNFDSFFNQS----THTYSFGSPDILPMFKDGASDPNKVDTWMYD 171

Query: 162 YPFPSF-------NVKDLDTVDNG----CIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFG 210
           + F  F       +      +D       +        + D +V   H LG D AGH + 
Sbjct: 172 HTFEDFTQSSIELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYR 231

Query: 211 VDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEE 270
             S+   + ++  +  +  +I+ +          + T  I   DHG +  G HG G    
Sbjct: 232 PYSAEYYDNVKYIDDQIPILIDKVN----KFFADDKTAFIFTADHGMSAFGSHGDGHPNN 287

Query: 271 VETTMFAMSTKKHTTLVPPEFDTSSCKQN------KDGKQMCISYIEQQHCQLCLGYPFL 324
             T + A     +  +  P   + +  +N      K                + + YP  
Sbjct: 288 TRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKN 347

Query: 325 SEG-AFIGHVNPELYALGSSSWNLDKSDLGN-FGTQSAA---NEWMKHYVDVLCVN---- 375
           S G   I +++ +     ++ +N  +S L      Q        + K Y   +  +    
Sbjct: 348 SVGELPIAYIDGKESDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHY 407

Query: 376 AWQVKRYIDVYSN-SSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRN---GDDGST 431
             +++  I   S   + +   +  ++      +    ++  +     +      G  G  
Sbjct: 408 LEEIETLIQRISEGENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWI 467

Query: 432 DISAL--LKEQIAE----------YLNFFSSVVELARSKWTEFNLNLMITGFGILVISLI 479
             S +  LK  I E            +     + +  +    +  +       +L     
Sbjct: 468 FFSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYF 527

Query: 480 LQFLAVFHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLI 539
             ++          +  +    + +   ++TI   S           +    L+      
Sbjct: 528 WSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAF 587

Query: 540 KLRYSVMR 547
                 +R
Sbjct: 588 YPFICGVR 595
 Score = 37.3 bits (86), Expect = 1.1
 Identities = 51/424 (12%), Positives = 100/424 (23%), Gaps = 108/424 (25%)

Query: 501 GAAFTLFIVTIRACSFLSNSYILE-----------EGKVANFLLATTGLIKLRYSVMRKT 549
           G    +F   I        S+ILE              V  F      L  + +      
Sbjct: 462 GFVGWIFFSFI----IFLKSFILENVIDDQKASPLSHAV--FGSIGILLNWILFYQHSP- 514

Query: 550 MRKEAFMFLAMVFVLRVSIDI----GLTKQAATSQFMSSSPSWMLGIA------------ 593
                  ++ ++F L     I     + +      F  +SP   + I             
Sbjct: 515 ----FNFYMYLLFPLYFWSYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVY 570

Query: 594 PDHPALTYAIEI-----------APILSVVILICVLYVAIAKAP---------------- 626
                 T+ +                LSV IL  +  V ++                   
Sbjct: 571 GFFHRWTFTLITNILAFYPFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLA 630

Query: 627 --NEGVWKYVTVGSMLLQVTGGRNR-----IPQTVYVIGLVQLCLLASARMFCTEKDKNW 679
                +  +  +  +  ++           I     ++ +    +++        ++   
Sbjct: 631 GLLIILSAFYALYKIHSRINSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQV 690

Query: 680 AIRTVALVSACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGV-ERRTKSDGQSKFSKLN 738
           A   +  VS    PI+             Y V    I               +S F  L 
Sbjct: 691 AGWIIFFVSLFVMPILHYRKPNND-----YKVRLLIIYLTFAPSFIILTISFESLFYFLF 745

Query: 739 PLCVVQW----------------------------SLLSICMFFASGHWCAFDGLRYGAA 770
              +VQW                              L    FF +G+  +       + 
Sbjct: 746 TSYMVQWIEIENKIKEMKTQKDENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESV 805

Query: 771 FVGFDEFVLIRQAILLTIETFGFSIIL--SVFGLPLLIPFHSQTPQAHGEKRHQLFQMYM 828
                 F       LL ++      +L   +  L L + F   T  +       +  +  
Sbjct: 806 CRLLPIFDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNF 865

Query: 829 LFGV 832
            + +
Sbjct: 866 FYLL 869
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  262 bits (664), Expect = 2e-68
 Identities = 41/329 (12%), Positives = 88/329 (26%), Gaps = 53/329 (16%)

Query: 15  FLLIHAIAILIFTRGFLLTRTELPFH---------STCSDVSLSPCLASPRSNHD----- 60
            L +       F   F++                 S  S                     
Sbjct: 1   MLFLSNFLSSSFLIFFIVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVVLMISC 60

Query: 61  SSSEPKP-WMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGN 119
                   +      +  L      +          PT +      + TG  P +  I  
Sbjct: 61  DGFRFGYQFKTDTPNIDLLISGGTEAKHGL--IPVFPTMTFPNHYSIATGLYPAYHGIIM 118

Query: 120 SFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFP-------------- 165
           +     +  + F        +    +G+  W        +    F               
Sbjct: 119 NKFTDPVTGEVF----NKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPSSEVLKSSWTCPE 174

Query: 166 ------SFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINK 219
                 + +V   + VD+  + H F  L  +  D+L+ +F   D +GH +G D   +   
Sbjct: 175 GYCPHFNLSVPLEERVDS-VLSH-FDHLEDEVPDLLMLYFDEPDQSGHNYGPDDPRVTTA 232

Query: 220 LEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLN--GDHGGGTAEEVETTMFA 277
           + + + ++ +VI  L+ +     +H    +I++GDHG   N   +      ++    +  
Sbjct: 233 VSRVDKMIGRVIKGLKQREIFDEVH----VILLGDHGMVTNCECNEKAIYIDD----LAD 284

Query: 278 MSTKKHTTLVPPEFDTSSCKQNKDGKQMC 306
                   +       +   Q     +  
Sbjct: 285 WIKIPAAWIQAYSPVLAINPQWGKDVENQ 313
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  260 bits (658), Expect = 9e-68
 Identities = 36/291 (12%), Positives = 77/291 (26%), Gaps = 40/291 (13%)

Query: 39  FHSTCSDVSLSPCLASPRSNHD--SSSEPKP-WMDKLTILQTLAFANDSSAKIFKAFADP 95
             S          L  P               +  +   +  L      +          
Sbjct: 39  PSSYVRRPQPPKKLNKPVVLLISCDGFRFGYQFKTETPNIDLLISRGTEAKTGL--IPVF 96

Query: 96  PTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFP 155
           PT +      + TG  P    I  +     +  + F      N      +G+  W     
Sbjct: 97  PTMTFPNHYSIATGLYPASHGIIMNKFTDPVSGELF----NRNLNPKWWLGEPLWVTAVN 152

Query: 156 NQFQKSYPFP---------------------SFNVKDLDTVDNGCIEHLFPTLFKDDWDV 194
                +  F                      + +V   + VD       F    ++  D 
Sbjct: 153 QGLMAATYFWPGADVHKGSWNCPKGFCKAPYNVSVPLEERVDTILN--YFDLPEREIPDF 210

Query: 195 LIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGD 254
           +  +F   D  GH +G D   +   + + + ++ ++I  LE +     +  +  +I++GD
Sbjct: 211 MALYFDEPDIQGHEYGPDDPRVTEAVSKVDKMIGRIIMGLEKRK----VFSDVHVILLGD 266

Query: 255 HGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQM 305
           HG   N D      ++    +          +       +   +     + 
Sbjct: 267 HGMVTNCDKKVIYIDD----LADWIKIPADWIQDYSPVLAMNPRWGKDVKN 313
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  256 bits (650), Expect = 9e-67
 Identities = 50/334 (14%), Positives = 97/334 (28%), Gaps = 49/334 (14%)

Query: 6   KNKKLTALGFLLIH--AIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLA------SPRS 57
           +NK L            IA + F   FL   +     S    ++ +              
Sbjct: 39  QNKVLLISLLSTTFTAVIAAVSFAFLFLSATSAAAGESKTIKITTTARSLTKLTHPIVIL 98

Query: 58  NHDSSSEPKP-WMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFID 116
                      +      +  L     S+          PT +      + TG  P    
Sbjct: 99  ISSDGFRFGYQFKAPTPNIHRLINNGTSAELGL--IPVFPTLTFPNHYSIVTGLYPPHHG 156

Query: 117 IGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFP----------- 165
           I N++    I  D F             +G+  W  +  +  + +  F            
Sbjct: 157 IINNYFVDPITGDKFSMASHEPKW---WLGEPLWETVAKHGKKAATYFWPGSEVIKPDWD 213

Query: 166 ---------SFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPM 216
                    + ++   + VD       F     +    +  +F   DH GH  G D   +
Sbjct: 214 CPSNYCIHYNGSIPFEERVDTVI--SYFDLPINEIPVFMTLYFEDPDHQGHQVGPDDPEI 271

Query: 217 INKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVE---- 272
              +   + ++ ++I  LE +    G+ E+  + ++GDHG     D      +++E    
Sbjct: 272 TQAVINIDKMIGRLIKGLEKR----GVFEDVNIFMVGDHGMVGTCDKKLIFLDDLEIPSN 327

Query: 273 -----TTMFAMSTKKHTTLVPPEFDTSSCKQNKD 301
                T + A+S     +        +S  Q+  
Sbjct: 328 WVQSYTPLLAISPPPEFSPAEIVAKMNSGLQSGK 361
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  256 bits (649), Expect = 1e-66
 Identities = 39/328 (11%), Positives = 91/328 (26%), Gaps = 53/328 (16%)

Query: 16  LLIHAIAILIFTRGFLLTRTELPFH---------STCSDVSLSPCLASPRSNHD-----S 61
           ++   ++++     F++                 S  S                      
Sbjct: 7   VISFKLSLIFLLNIFIVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVVLMISCD 66

Query: 62  SSEPKP-WMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNS 120
                  +      +  L      +          PT +      + TG  P +  I  +
Sbjct: 67  GFRFGYQFKTDTPNIDLLISGGTEAKHGL--IPVFPTMTFPNHYSIATGLYPAYHGIIMN 124

Query: 121 FGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFP--------------- 165
                +  + F        +    +G+  W        +    F                
Sbjct: 125 KFTDPVTGEVF----NKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPGSEVLKSSWTCPEG 180

Query: 166 -----SFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKL 220
                + +V   + VD+  + H F  L  +  D+L+ +F   D +GH +G D   +   +
Sbjct: 181 YCPHFNLSVPLEERVDS-VLSH-FDHLEDEVPDLLMLYFDEPDQSGHNYGPDDPRVTTAV 238

Query: 221 EQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLN--GDHGGGTAEEVETTMFAM 278
            + + ++ +VI  L+ +     +H    +I++GDHG   N   +      ++    +   
Sbjct: 239 SRVDKMIGRVIKGLKQREIFDEVH----VILLGDHGMVTNCECNEKAIYIDD----LADW 290

Query: 279 STKKHTTLVPPEFDTSSCKQNKDGKQMC 306
                  +       +   Q     +  
Sbjct: 291 IKIPAAWIQAYSPVLAINPQWGKDVENQ 318
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  246 bits (623), Expect = 1e-63
 Identities = 44/317 (13%), Positives = 88/317 (26%), Gaps = 45/317 (14%)

Query: 5   LKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSP-------CLASP-- 55
           + +  +     L+            FL   ++ P  S                 L     
Sbjct: 47  ISSCFIFTSLLLVTCIALSAASAFAFLFFSSQKPVLSLNQISKSPAFDRSVARPLKKLDK 106

Query: 56  ---RSNHDSSSEPKP-WMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGL 111
                           +  KL  +  L      +          PT +      + TG  
Sbjct: 107 PVVLLISSDGFRFGYQFKTKLPSIHRLIANGTEAETGL--IPVFPTLTFPNHYSIVTGLY 164

Query: 112 PTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFP------ 165
           P +  I N+        + F             +G+  W  +     + +  F       
Sbjct: 165 PAYHGIINNHFVDPETGNVFTMASHEPEW---WLGEPLWETVVNQGLKAATYFWPGSEVH 221

Query: 166 --------------SFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGV 211
                         + +V   D VD   + + F     +    +  +F   DH GH  G 
Sbjct: 222 KGSWNCPQGLCQNYNGSVPFDDRVDT-ILSY-FDLPSNEIPSFMTLYFEDPDHQGHQVGP 279

Query: 212 DSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEV 271
           D   +   +   + ++ ++I+ LE +    G+ E+  +I++GDHG     D      ++ 
Sbjct: 280 DDPQITEAVVNIDRLIGRLIDGLEKR----GIFEDVTMIMVGDHGMVGTCDKKLVVLDD- 334

Query: 272 ETTMFAMSTKKHTTLVP 288
                 + +       P
Sbjct: 335 LAPWIKIPSSWVQYYTP 351
>ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyrophosphatase 2;
           phosphodiesterase I/nucleotide pyrophosphatase 2
           (autotaxin) [Rattus norvegicus]
 pir||A55453 plasma cell membrane glycoprotein PC-1, brain specific - rat
 dbj|BAA05910.1| (D28560) phosphodiesterase I [Rattus norvegicus]
          Length = 885

 Score =  243 bits (615), Expect = 1e-62
 Identities = 39/235 (16%), Positives = 67/235 (27%), Gaps = 29/235 (12%)

Query: 38  PFHSTCSDVSLSPCLASPRSNHDSSSEPKPWM---DKLTILQTLAFANDSSAKIFKAFAD 94
              S C  V   P                        +  ++ L             +  
Sbjct: 150 NQSSECLQVCPPP----LIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTH-----VPYTR 200

Query: 95  P--PTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGK----RLVMMGDD 148
           P  PT +   L  L TG  P    I  +     +    F     L G+         G  
Sbjct: 201 PVYPTKTFPNLYTLATGLYPESHGIVGNSMYDPV----FDASFHLRGREKFNHRWWGGQP 256

Query: 149 TWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHI 208
            W        +    F S ++     +    ++ L      +   V   +    D +GH 
Sbjct: 257 LWITATKQGVRAGTFFWSVSIPHERRILT-ILQWL-SLPDNERPSVYAFYSEQPDFSGHK 314

Query: 209 FGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTL-NGD 262
           +G     M N L + +  + ++++ L+       LH    +I +GDHG      D
Sbjct: 315 YGPFGPEMTNPLREIDKTVGQLMDGLKQL----RLHRCVNVIFVGDHGMEDVTCD 365
>gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase/phosphodiesterase 2 [Mus
           musculus]
          Length = 862

 Score =  240 bits (609), Expect = 5e-62
 Identities = 37/233 (15%), Positives = 69/233 (28%), Gaps = 26/233 (11%)

Query: 43  CSDVSLSPCLAS-----PRSNHDSSSEPKPWM---DKLTILQTLAFANDSSAKIFKAFAD 94
           C ++ +  C A                          +  ++ L      +  +      
Sbjct: 148 CEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYM---RPV 204

Query: 95  PPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGK----RLVMMGDDTW 150
            PT +   L  L TG  P    I  +     +    F     L G+         G   W
Sbjct: 205 YPTKTFPNLYTLATGLYPESHGIVGNSMYDPV----FDATFHLRGREKFNHRWWGGQPLW 260

Query: 151 TQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFG 210
                   +    F S ++     +    ++ L      +   V   +    D +GH +G
Sbjct: 261 ITATKQGVRAGTFFWSVSIPHERRILT-ILQWL-SLPDNERPSVYAFYSEQPDFSGHKYG 318

Query: 211 VDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTL-NGD 262
                M N L + +  + ++++ L+       LH    +I +GDHG      D
Sbjct: 319 PFGPEMTNPLREIDKTVGQLMDGLKQLK----LHRCVNVIFVGDHGMEDVTCD 367
>ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyrophosphatase 2 [Mus
           musculus]
 gb|AAD46480.1|AF123542_1 (AF123542) phosphodiesterase I/nucleotide pyrophosphatase [Mus
           musculus]
          Length = 862

 Score =  240 bits (609), Expect = 6e-62
 Identities = 37/233 (15%), Positives = 69/233 (28%), Gaps = 26/233 (11%)

Query: 43  CSDVSLSPCLAS-----PRSNHDSSSEPKPWM---DKLTILQTLAFANDSSAKIFKAFAD 94
           C ++ +  C A                          +  ++ L      +  +      
Sbjct: 148 CEEIRVPECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHAPYM---RPV 204

Query: 95  PPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGK----RLVMMGDDTW 150
            PT +   L  L TG  P    I  +     +    F     L G+         G   W
Sbjct: 205 YPTKTFPNLYTLATGLYPESHGIVGNSMYDPV----FDATFHLRGREKFNHRWWGGQPLW 260

Query: 151 TQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFG 210
                   +    F S ++     +    ++ L      +   V   +    D +GH +G
Sbjct: 261 ITATKQGVRAGTFFWSVSIPHERRILT-ILQWL-SLPDNERPSVYAFYSEQPDFSGHKYG 318

Query: 211 VDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTL-NGD 262
                M N L + +  + ++++ L+       LH    +I +GDHG      D
Sbjct: 319 PFGPEMTNPLREIDKTVGQLMDGLKQLK----LHRCVNVIFVGDHGMEDVTCD 367
>dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens]
          Length = 863

 Score =  238 bits (602), Expect = 4e-61
 Identities = 38/233 (16%), Positives = 69/233 (29%), Gaps = 26/233 (11%)

Query: 43  CSDVSLSPCLAS-----PRSNHDSSSEPKPWM---DKLTILQTLAFANDSSAKIFKAFAD 94
           C ++  + C A                          +  ++ L      S  +      
Sbjct: 149 CEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYM---RPV 205

Query: 95  PPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGK----RLVMMGDDTW 150
            PT +   L  L TG  P    I  +     +    F     L G+         G   W
Sbjct: 206 YPTKTFPNLYTLATGLYPESHGIVGNSMYDPV----FDATFHLRGREKFNHRWWGGQPLW 261

Query: 151 TQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFG 210
                   +    F S  +     +    ++ L      +   V   +    D +GH +G
Sbjct: 262 ITATKQGVKAGTFFWSVVIPHERRILT-ILQWL-TLPDHERPSVYAFYSEQPDFSGHKYG 319

Query: 211 VDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTL-NGD 262
                M N L + + ++ ++++ L+       LH    +I +GDHG      D
Sbjct: 320 PFGPEMTNPLREIDKIVGQLMDGLKQLK----LHRCVNVIFVGDHGMEDVTCD 368
>ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phosphodiesterase 2
           (autotaxin); Phosphodiesterase I/nucleotide
           pyrophosphatase 2; autotaxin; phosphodiesterase
           I/nucleotide pyrophosphatase 2 (autotaxin) [Homo
           sapiens]
 gb|AAB00855.1| (L46720) autotaxin-t [Homo sapiens]
          Length = 863

 Score =  238 bits (602), Expect = 4e-61
 Identities = 38/233 (16%), Positives = 69/233 (29%), Gaps = 26/233 (11%)

Query: 43  CSDVSLSPCLAS-----PRSNHDSSSEPKPWM---DKLTILQTLAFANDSSAKIFKAFAD 94
           C ++  + C A                          +  ++ L      S  +      
Sbjct: 149 CEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYM---RPV 205

Query: 95  PPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGK----RLVMMGDDTW 150
            PT +   L  L TG  P    I  +     +    F     L G+         G   W
Sbjct: 206 YPTKTFPNLYTLATGLYPESHGIVGNSMYDPV----FDATFHLRGREKFNHRWWGGQPLW 261

Query: 151 TQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFG 210
                   +    F S  +     +    ++ L      +   V   +    D +GH +G
Sbjct: 262 ITATKQGVKAGTFFWSVVIPHERRILT-ILQWL-TLPDHERPSVYAFYSEQPDFSGHKYG 319

Query: 211 VDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTL-NGD 262
                M N L + + ++ ++++ L+       LH    +I +GDHG      D
Sbjct: 320 PFGPEMTNPLREIDKIVGQLMDGLKQLK----LHRCVNVIFVGDHGMEDVTCD 368
>pir||T33724 hypothetical protein - Zymomonas mobilis
 gb|AAC70363.1| (AF086791) unknown [Zymomonas mobilis]
          Length = 429

 Score =  236 bits (598), Expect = 1e-60
 Identities = 44/297 (14%), Positives = 80/297 (26%), Gaps = 46/297 (15%)

Query: 3   TYLKNKKLTALGFLLIHA--IAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSNHD 60
             LK +K    G L +      + +     +     +   S                   
Sbjct: 6   KPLKKRKPWISGILSLLLGCAGLSVVHSDAIAATAHVTAQSKTP----------LILISI 55

Query: 61  SSSEPKPWM-DKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDI-G 118
                          L +LA     +  +       P+ +      L TG  P    I G
Sbjct: 56  DGFRADYIKRGLTPNLVSLAENGSYAKVM---HPSFPSITFPNHYTLVTGLYPDHHGIVG 112

Query: 119 NSFGAPAIVEDN-FINQLVLNGKRLVMM--GDDTWTQLFPNQFQKSYPFP---------- 165
           N+     I  D+ F                G+  W          +  F           
Sbjct: 113 NNMDDAHITPDSHFKMSDHQAATDRRWWDEGEPLWVTAEKQGVVSATMFWPGSEADIEGV 172

Query: 166 --------SFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMI 217
                     +V   + VD      L     K     +  +F  VDHAGH++G DS  + 
Sbjct: 173 RPEMWRQFDSHVPFSERVDQ-VFSWL-AYPKKKRPQFITLYFENVDHAGHLYGPDSQEVN 230

Query: 218 NKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETT 274
           + L + +  + +++  L+ +           L+++ DHG             ++   
Sbjct: 231 DNLVKIDQTIGQLVQGLKQRGI------KANLVIVSDHGMAATSSDRVVALNKILDP 281
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  233 bits (591), Expect = 8e-60
 Identities = 47/300 (15%), Positives = 86/300 (28%), Gaps = 39/300 (13%)

Query: 14  GFLLIHAIAILIFTRGFLLTRT----ELPFHSTCSDVSLSPCLASPRSNHDSSSEPKP-W 68
             L         +    L          P  +  + V L   +                 
Sbjct: 49  LLLTAALAVATSYLLLILPRTPLSAAPAPAAAARAQVKLEKPV--VILISSDGFRFGYQH 106

Query: 69  MDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVE 128
                 +  L     S+A         PT +      + TG  P+   I N++    I  
Sbjct: 107 KAATPHIHRLIGNGTSAATGLVPI--FPTLTFPNHYSIATGLYPSSHGIINNYFPDPISG 164

Query: 129 DNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFP--------------------SFN 168
           D F             +G+  W        Q +  F                     + +
Sbjct: 165 DYFTMSSHEPKW---WLGEPLWVTAADQGIQAATYFWPGSEVKKGSWDCPDKYCRHYNGS 221

Query: 169 VKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLE 228
           V   + VD   + + F     +    L  +F   DH GH  G D   +   + + + ++ 
Sbjct: 222 VPFEERVD-AILGY-FDLPSDEMPQFLTLYFEDPDHQGHQVGPDDPAITEAVVRIDEMIG 279

Query: 229 KVINILESQAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVP 288
           ++I  LE +    G+ E+  +I++GDHG     D      +E       +      ++ P
Sbjct: 280 RLIAGLEER----GVFEDVNVILVGDHGMVGTCDKKLVFLDE-LAPWIKLEEDWVLSMTP 334
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  230 bits (582), Expect = 9e-59
 Identities = 78/275 (28%), Positives = 117/275 (42%), Gaps = 48/275 (17%)

Query: 187 LFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHEN 246
           +   +WDVLIAHFLGVDH GH  G     M  KL Q + V++ ++  LE+         +
Sbjct: 1   MDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEN---------D 51

Query: 247 TMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQMC 306
           T+L+V GDHG T NGDHGG +  EV   +F  S        PPE +              
Sbjct: 52  TLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPE-EPEVIP--------Q 102

Query: 307 ISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSAANEWMK 366
           +S +      L L  PF +    IG V  EL++ G  S         +   Q++A     
Sbjct: 103 VSLVPTLALLLGLPIPFGN----IGEVMAELFSGGEDS-----QPHSSALAQASA----- 148

Query: 367 HYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRNG 426
                L +NA QV R++  YS ++     + ++ ++ +L+S A  ++    + +L    G
Sbjct: 149 -----LHLNAQQVSRFLHTYS-AATQDLQAKELHQLQNLFSKASADY----QWLLQSPKG 198

Query: 427 DDGSTDISALLKEQIAEYLNFFSSVVELARSKWTE 461
                   A L   IAE   F      +    W  
Sbjct: 199 A------EATLPTVIAELQQFLRGARAMCIESWAR 227
 Score =  191 bits (483), Expect = 3e-47
 Identities = 59/280 (21%), Positives = 101/280 (36%), Gaps = 40/280 (14%)

Query: 641 LQVTGGRNRIPQTVYVIGLVQLCLLASARMFCTEKDKNWAIRT--VALVSACSSPIILLS 698
            QV+   +        +   +L  L +     +  D  W +++   A  +  +    L  
Sbjct: 154 QQVSRFLHTYSAATQDLQAKELHQLQNLFSKASA-DYQWLLQSPKGAEATLPTVIAELQQ 212

Query: 699 GKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVV-QWSLLSICMFFASG 757
             +G+    +   A + +  L            +      P   V  W+L++   F+++G
Sbjct: 213 FLRGARAMCIESWARFSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTG 272

Query: 758 HWCAFDGLRYGAAFVGFDE--FVLIRQAILLT-IETFGFSIILSVFGLPLLIP------- 807
           H   F  + + AAFVGF E          LL    TF   ++ +V    LL+        
Sbjct: 273 HQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQ 332

Query: 808 ---FHSQTPQAHGEKR-----------------------HQLFQMYMLFGVISATTVTAT 841
                 Q P    + R                         L Q+ + +  I    + A 
Sbjct: 333 GLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILAC 392

Query: 842 ILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASA 881
            L  +I RRHLMVW +FAPKF+F+ V  I++ + + L  A
Sbjct: 393 ALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIA 432
>ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH01030.1|AAH01030 (BC001030) Similar to phosphatidylinositol glycan, class O [Homo
           sapiens]
          Length = 454

 Score =  218 bits (552), Expect = 2e-55
 Identities = 73/275 (26%), Positives = 113/275 (40%), Gaps = 48/275 (17%)

Query: 187 LFKDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHEN 246
           +   +W+V   H LGVDH GH  G     M  KL Q + V++ ++  LE+         +
Sbjct: 1   MDSGEWEVSNQHVLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEN---------D 51

Query: 247 TMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQMC 306
           T+L+V GDHG T NGDHGG +  EV   +F  S        PPE +              
Sbjct: 52  TLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPE-EPEVIP--------Q 102

Query: 307 ISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSAANEWMK 366
           +S +      L L  PF +    IG V  EL++ G  S         +   Q++A     
Sbjct: 103 VSLVPTLALLLGLPIPFGN----IGEVMAELFSGGEDS-----QPHSSALAQASA----- 148

Query: 367 HYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRNG 426
                L +NA QV R++  YS ++     + ++ ++ +L+S A  ++    + +L    G
Sbjct: 149 -----LHLNAQQVSRFLHTYS-AATQDLQAKELHQLQNLFSKASADY----QWLLQSPKG 198

Query: 427 DDGSTDISALLKEQIAEYLNFFSSVVELARSKWTE 461
                   A L   IAE   F      +    W  
Sbjct: 199 A------EATLPTVIAELQQFLRGARAMCIESWAR 227
 Score =  193 bits (486), Expect = 1e-47
 Identities = 59/280 (21%), Positives = 101/280 (36%), Gaps = 40/280 (14%)

Query: 641 LQVTGGRNRIPQTVYVIGLVQLCLLASARMFCTEKDKNWAIRT--VALVSACSSPIILLS 698
            QV+   +        +   +L  L +     +  D  W +++   A  +  +    L  
Sbjct: 154 QQVSRFLHTYSAATQDLQAKELHQLQNLFSKASA-DYQWLLQSPKGAEATLPTVIAELQQ 212

Query: 699 GKQGSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPLCVV-QWSLLSICMFFASG 757
             +G+    +   A + +  L            +      P   V  W+L++   F+++G
Sbjct: 213 FLRGARAMCIESWARFSLSFLLLHLLAAGIPVTTPGPFTVPWQAVSAWALMATQTFYSTG 272

Query: 758 HWCAFDGLRYGAAFVGFDE--FVLIRQAILLT-IETFGFSIILSVFGLPLLIP------- 807
           H   F  + + AAFVGF E          LL    TF   ++ +V    LL+        
Sbjct: 273 HQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAVGCPLLLLWPFLCESQ 332

Query: 808 ---FHSQTPQAHGEKR-----------------------HQLFQMYMLFGVISATTVTAT 841
                 Q P    + R                         L Q+ + +  I    + A 
Sbjct: 333 GLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQLGLKYLFILGIQILAC 392

Query: 842 ILCVTIQRRHLMVWGLFAPKFVFDVVDLILTDLLICLASA 881
            L  +I RRHLMVW +FAPKF+F+ V  I++ + + L  A
Sbjct: 393 ALAASILRRHLMVWKVFAPKFIFEAVGFIVSSVGLLLGIA 432
>dbj|BAB17014.1| (AB050262) hypothetical protein [Macaca fascicularis]
          Length = 333

 Score =  218 bits (552), Expect = 3e-55
 Identities = 63/323 (19%), Positives = 109/323 (33%), Gaps = 49/323 (15%)

Query: 194 VLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMG 253
           +LI H+LG+DH GHI G +S  + +KL + +SVL K+   L+S+     L    +L++ G
Sbjct: 1   MLILHYLGLDHIGHISGPNSPLIGHKLSEMDSVLMKIHTSLQSKERETPL--PNLLVLCG 58

Query: 254 DHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNKDGKQMCISYIEQQ 313
           DHG +  G HG  + EEV T +  +S+         E      +  K             
Sbjct: 59  DHGMSETGSHGASSMEEVNTPLILISSAF-------ERKPGDIRHPKH--VQQTDVAATL 109

Query: 314 HCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFGTQSAANEWMKHYVDVLC 373
              L L  P  S G                          +          M+  +  L 
Sbjct: 110 AIALGLPIPKDSVG--------------------------SLLFPVVEGRPMREQLRFLH 143

Query: 374 VNAWQVKRYIDVYSNSSVVGFSSDDMSRISDLYSAAEQNWSNSVKHILMDRNGDDGSTDI 433
           +N  Q+ + +     S       +       L+    + +       ++   G       
Sbjct: 144 LNTVQLSKLLQENVPSYEKDPGFEQFKMSERLHGNWIRLYLEEKHSEVLFNLGSKVLRQY 203

Query: 434 SALLKEQIAEYLNFFSSVVELARSKWTEFNLNLMITGFGILVISLILQFLAVFHGD-KSY 492
            A LK                      ++++  M+ G  +++  L L  L+V     +  
Sbjct: 204 LAALKTLSLSLSTQV-----------AQYDMYSMMVGTVVVLEVLTLLLLSVPQALHRKA 252

Query: 493 AVGSWLSTGAAFTLFIVTIRACS 515
            +   LS+     LF + I   S
Sbjct: 253 ELEVPLSSPEFSLLFYLVILVLS 275
>dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 179

 Score =  192 bits (485), Expect = 2e-47
 Identities = 33/174 (18%), Positives = 55/174 (30%), Gaps = 15/174 (8%)

Query: 189 KDDWDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTM 248
             D  V   H LG+D  GH    DS   +  ++  +  ++++++ + +          + 
Sbjct: 1   HRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYY---NNDGASS 57

Query: 249 LIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLV--PPEFDTSSCKQN----KDG 302
            +   DHG +  G HG G  +   T + A      +         D  S   N    K  
Sbjct: 58  WVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRI 117

Query: 303 KQMCISYIEQQHCQLCLGYPFLSEGAFIGHVNPELYALGSSSWNLDKSDLGNFG 356
                         + L +P  S G         L  L  SS    +  L N  
Sbjct: 118 DIQQADIAALMSYLVGLNFPVNSVGQI------PLDYLDCSSRRKAEVALMNAL 165
>pir||A55144 autotaxin precursor - human
 gb|AAA64785.1| (L35594) autotaxin [Homo sapiens]
          Length = 915

 Score =  185 bits (466), Expect = 3e-45
 Identities = 26/185 (14%), Positives = 45/185 (24%), Gaps = 21/185 (11%)

Query: 43  CSDVSLSPCLAS-----PRSNHDSSSEPKPWM---DKLTILQTLAFANDSSAKIFKAFAD 94
           C ++  + C A                          +  ++ L      S  +      
Sbjct: 149 CEEIKAAECPAGFVRPPLIIFSVDGFRASYMKKGSKVMPNIEKLRSCGTHSPYM---RPV 205

Query: 95  PPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGK----RLVMMGDDTW 150
            PT +   L  L TG  P    I  +     +    F     L G+         G   W
Sbjct: 206 YPTKTFPNLYTLATGLYPESHGIVGNSMYDPV----FDATFHLRGREKFNHRWWGGQPLW 261

Query: 151 TQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPTLFKDDWDVLIAHFLGVDHAGHIFG 210
                   +    F S  +     +    +  L      +   V   +    D +GH +G
Sbjct: 262 ITATKQGVKAGTFFWSVVIPHERRILT-ILRWL-TLPDHERPSVYAFYSEQPDFSGHKYG 319

Query: 211 VDSSP 215
                
Sbjct: 320 PFGPE 324
 Score = 56.3 bits (135), Expect = 2e-06
 Identities = 10/48 (20%), Positives = 21/48 (42%), Gaps = 5/48 (10%)

Query: 216 MINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTL-NGD 262
           M N L + + ++ ++++ L+             +I +GDHG      D
Sbjct: 377 MTNPLREIDKIVGQLMDGLKQLKLR----RCVNVIFVGDHGMEDVTCD 420
>dbj|BAB55130.1| (AK027465) unnamed protein product [Homo sapiens]
          Length = 549

 Score =  175 bits (441), Expect = 2e-42
 Identities = 55/331 (16%), Positives = 103/331 (30%), Gaps = 36/331 (10%)

Query: 566 VSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLYVAIAK- 624
             +   L +             W+     DH A    +    +L V +L+      ++K 
Sbjct: 231 CRLLRSLNQTGVQWAHRPDLGHWLTSS--DHKAELSVLAALSLLVVFVLVQRGCSPVSKA 288

Query: 625 APNEGVWKYVTVGSMLLQV-TGGRNRIPQTVY-VIGLVQLCLLASARMFCTEKDKNWAIR 682
           A   G+       + +  V    R         +I    + +     +F   KD   +  
Sbjct: 289 ALALGLLGVYCYRAAIGSVRFPWRPDSKDISKGIIEARFVYVFVLGILFTGTKDLLKSQV 348

Query: 683 TVALV------------SACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDG 730
             A                     +L       +LA   L+       +    R   ++ 
Sbjct: 349 IAADFKLKTVGLWEIYSGLVLLAALLFRPHNLPVLAFSLLIQTLMTKFIWKPLRHDAAEI 408

Query: 731 QSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIET 790
                       V         F+  G+      +   A FVG D +V I  A+LLT   
Sbjct: 409 -----------TVMHYWFGQAFFYFQGNSNNIATVDISAGFVGLDTYVEI-PAVLLTAFG 456

Query: 791 FGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTATILCVTIQRR 850
                +L    L   +   +++          L      + +I +  V   I+ VT  R 
Sbjct: 457 TYAGPVLWASHLVHFLSSETRS-------GSALSHACFCYALICSIPVFTYIVLVTSLRY 509

Query: 851 HLMVWGLFAPKFVFDVVDLILTDLLICLASA 881
           HL +W +F+PK +++ + L++T  +    +A
Sbjct: 510 HLFIWSVFSPKLLYEGMHLLITAAVCVFFTA 540
 Score = 42.3 bits (99), Expect = 0.039
 Identities = 8/29 (27%), Positives = 14/29 (47%)

Query: 512 RACSFLSNSYILEEGKVANFLLATTGLIK 540
              S  ++S++ EE +   FL+ T  L  
Sbjct: 127 HVLSLGASSFVEEEHQTWYFLVNTLCLAL 155
>ref|NP_060203.1| (NM_017733) hypothetical protein FLJ20265 [Homo sapiens]
 dbj|BAA91046.1| (AK000272) unnamed protein product [Homo sapiens]
 gb|AAH01249.1|AAH01249 (BC001249) hypothetical protein FLJ20265 [Homo sapiens]
          Length = 604

 Score =  175 bits (441), Expect = 2e-42
 Identities = 55/331 (16%), Positives = 103/331 (30%), Gaps = 36/331 (10%)

Query: 566 VSIDIGLTKQAATSQFMSSSPSWMLGIAPDHPALTYAIEIAPILSVVILICVLYVAIAK- 624
             +   L +             W+     DH A    +    +L V +L+      ++K 
Sbjct: 286 CRLLRSLNQTGVQWAHRPDLGHWLTSS--DHKAELSVLAALSLLVVFVLVQRGCSPVSKA 343

Query: 625 APNEGVWKYVTVGSMLLQV-TGGRNRIPQTVY-VIGLVQLCLLASARMFCTEKDKNWAIR 682
           A   G+       + +  V    R         +I    + +     +F   KD   +  
Sbjct: 344 ALALGLLGVYCYRAAIGSVRFPWRPDSKDISKGIIEARFVYVFVLGILFTGTKDLLKSQV 403

Query: 683 TVALV------------SACSSPIILLSGKQGSMLALVYLVAGYCIMRLEGVERRTKSDG 730
             A                     +L       +LA   L+       +    R   ++ 
Sbjct: 404 IAADFKLKTVGLWEIYSGLVLLAALLFRPHNLPVLAFSLLIQTLMTKFIWKPLRHDAAEI 463

Query: 731 QSKFSKLNPLCVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIET 790
                       V         F+  G+      +   A FVG D +V I  A+LLT   
Sbjct: 464 -----------TVMHYWFGQAFFYFQGNSNNIATVDISAGFVGLDTYVEI-PAVLLTAFG 511

Query: 791 FGFSIILSVFGLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTATILCVTIQRR 850
                +L    L   +   +++          L      + +I +  V   I+ VT  R 
Sbjct: 512 TYAGPVLWASHLVHFLSSETRS-------GSALSHACFCYALICSIPVFTYIVLVTSLRY 564

Query: 851 HLMVWGLFAPKFVFDVVDLILTDLLICLASA 881
           HL +W +F+PK +++ + L++T  +    +A
Sbjct: 565 HLFIWSVFSPKLLYEGMHLLITAAVCVFFTA 595
 Score = 52.4 bits (125), Expect = 3e-05
 Identities = 16/116 (13%), Positives = 34/116 (28%), Gaps = 12/116 (10%)

Query: 401 RISDLYSAAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIAEYLNFFSSVVELARSKWT 460
               L+    + +       ++   G          LK                      
Sbjct: 1   MSERLHGNWIRLYLEEKHSEVLFNLGSKVLRQYLDALKTLSLSLSAQV-----------A 49

Query: 461 EFNLNLMITGFGILVISLILQFLAVFHGDKSYAVGSWLSTGAAFT-LFIVTIRACS 515
           ++++  M+ G  +++  L L  L+V    +  A      +   F+ LF + I   S
Sbjct: 50  QYDIYSMMVGTVVVLEVLTLLLLSVPQALRRKAELEVPLSSPGFSLLFYLVILVLS 105
 Score = 42.3 bits (99), Expect = 0.039
 Identities = 8/29 (27%), Positives = 14/29 (47%)

Query: 512 RACSFLSNSYILEEGKVANFLLATTGLIK 540
              S  ++S++ EE +   FL+ T  L  
Sbjct: 182 HVLSLGASSFVEEEHQTWYFLVNTLCLAL 210
>ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phosphodiesterase 3;
           phosphodiesterase I/nucleotide pyrophosphatase 3;
           phosphodiesterase-I beta; gp130RB13-6; bovine intestinal
           phosphodiesterase [Homo sapiens]
 gb|AAC51813.1| (AF005632) phosphodiesterase I/nucleotide pyrophosphatase beta
           [Homo sapiens]
          Length = 875

 Score =  169 bits (426), Expect = 2e-40
 Identities = 34/246 (13%), Positives = 68/246 (26%), Gaps = 33/246 (13%)

Query: 36  ELPFHSTCSDVSLSPCLASPRSNHDSSSEPKPWM---DKLTILQTLAFANDSSAKIFKAF 92
           +    S C +    P +             +        +  +  L      S  +    
Sbjct: 145 DTAQQSQCPEGFDLPPV---ILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKYM---R 198

Query: 93  ADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLVLNGKRLVMMGDDTWTQ 152
           A  PT +      + TG  P    I ++      +  NF              G   W  
Sbjct: 199 AMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLT 258

Query: 153 LFPNQFQKSYPFP------------------SFNVKDLDTVDNGCIEHLFPTLFKDDWDV 194
                 + +  F                   + +V   + +    ++ L      +    
Sbjct: 259 AMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTL-LKWL-DLPKAERPRF 316

Query: 195 LIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGD 254
              +F   D +GH  G  S+ +I  L+  +     ++  L+ +     LH    +I++ D
Sbjct: 317 YTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQR----NLHNCVNIILLAD 372

Query: 255 HGQTLN 260
           HG    
Sbjct: 373 HGMDQT 378
>ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster]
          Length = 656

 Score =  166 bits (419), Expect = 9e-40
 Identities = 27/215 (12%), Positives = 58/215 (26%), Gaps = 17/215 (7%)

Query: 237 QAGPGGLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDT--S 294
           +     +H++T+L++        +G HGGG+ EE E                   D   +
Sbjct: 3   RKRHTFIHQHTVLLI--------SGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLN 54

Query: 295 SCKQNKDGKQMCISYIEQQHCQLCLGYPFLSEGA-FIGHVNPELYALGSSSWNLDKSDLG 353
           +    +  K   I         + L  P  +      G++         S        L 
Sbjct: 55  NGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLT 114

Query: 354 NF---GTQSAANEWMKHYVDVLCVNAWQVKRYIDVYSNSSVVGFSSDDMSRI---SDLYS 407
                        + K       ++  Q+  Y +   +   +G+ S  +        +  
Sbjct: 115 QAKAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVAL 174

Query: 408 AAEQNWSNSVKHILMDRNGDDGSTDISALLKEQIA 442
            + + + N     L+              L +   
Sbjct: 175 KSLKFYHNYYHIPLVVTTVLALLGWQFYQLVKLSQ 209
CPU time:   253.96 user secs.	    3.22 sys. secs	  257.18 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.316    0.176    0.453 

Gapped
Lambda     K      H
   0.270   0.0616    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 586114607
Number of Sequences: 887402
Number of extensions: 32822949
Number of successful extensions: 161692
Number of sequences better than 10.0: 1338
Number of HSP's better than 10.0 without gapping: 128
Number of HSP's successfully gapped in prelim test: 1242
Number of HSP's that attempted gapping in prelim test: 158820
Number of HSP's gapped (non-prelim): 3032
length of query: 884
length of database: 277,845,442
effective HSP length: 57
effective length of query: 827
effective length of database: 227,263,528
effective search space: 187946937656
effective search space used: 187946937656
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.7 bits)
S2: 78 (34.4 bits)