IMP GPI Biosynthesis Report IMP-Bioinformatics
GPI Biosynthesis Main Page  
GPI Site Motif   GPI Site Prediction   Home Page B.E.  

GPI Anchor Biosynthesis Report: AAB93646.1 (PIG-O family, Caenorhabditis elegans)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (905 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 5

Distribution of 60 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments: (bits) Value
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 1240 0.0
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 607 e-172
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 601 e-170
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 542 e-153
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 502 e-140
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 467 e-130
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 435 e-120
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 417 e-115
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 409 e-112
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 405 e-111
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 400 e-110
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 398 e-109
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 377 e-103
sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CH... 368 e-100
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 352 2e-95
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 330 6e-89
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 322 2e-86
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 316 1e-84
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 316 1e-84
dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located... 287 6e-76
pir||A39216 plasma cell membrane glycoprotein PC-1 - human >gi|7... 287 7e-76
ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phos... 286 1e-75
gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattu... 286 1e-75
ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phos... 285 2e-75
ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phos... 285 3e-75
gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphat... 284 3e-75
emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucle... 284 4e-75
gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphata... 283 1e-74
pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse 283 1e-74
ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyro... 283 1e-74
sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodieste... 281 2e-74
dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus] 276 2e-72
ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus ... 275 2e-72
gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norve... 275 2e-72
pir||A57080 cell surface antigen RB13-6 - rat >gi|806379|emb|CAA... 272 2e-71
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 267 4e-70
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 266 1e-69
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 262 2e-68
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 261 3e-68
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 257 7e-67
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 257 8e-67
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 250 6e-65
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 242 2e-62
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 237 5e-61
gb|AAD05192.1| (AC005587) phosphodiesterase I beta [Homo sapiens] 232 2e-59
ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo ... 229 1e-58
pir||T33724 hypothetical protein - Zymomonas mobilis >gi|3089614... 229 2e-58
Alignments
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score = 1240 bits (3175), Expect = 0.0
 Identities = 905/905 (100%), Positives = 905/905 (100%)

Query: 1   MGSIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVIL 60
           MGSIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVIL
Sbjct: 1   MGSIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVIL 60

Query: 61  ILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRL 120
           ILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRL
Sbjct: 61  ILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRL 120

Query: 121 KALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTA 180
           KALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTA
Sbjct: 121 KALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTA 180

Query: 181 AYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDH 240
           AYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDH
Sbjct: 181 AYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDH 240

Query: 241 CGHKFGPSHPVMADTLRKMDRIIGQTIETMKSDDHGMTSTGDHGGESENEIRAGILVHSK 300
           CGHKFGPSHPVMADTLRKMDRIIGQTIETMKSDDHGMTSTGDHGGESENEIRAGILVHSK
Sbjct: 241 CGHKFGPSHPVMADTLRKMDRIIGQTIETMKSDDHGMTSTGDHGGESENEIRAGILVHSK 300

Query: 301 KHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLFTRDLWEIARQMMGFVWQDS 360
           KHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLFTRDLWEIARQMMGFVWQDS
Sbjct: 301 KHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLFTRDLWEIARQMMGFVWQDS 360

Query: 361 VGIFAETYAAQKNFGELHSHTIRDSNTMEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFS 420
           VGIFAETYAAQKNFGELHSHTIRDSNTMEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFS
Sbjct: 361 VGIFAETYAAQKNFGELHSHTIRDSNTMEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFS 420

Query: 421 LVEAIMFLITNEVMSLEWIIYRTGCGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSII 480
           LVEAIMFLITNEVMSLEWIIYRTGCGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSII
Sbjct: 421 LVEAIMFLITNEVMSLEWIIYRTGCGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSII 480

Query: 481 SMCHKALQIRISIKSMLSAKVIGPILVIIHSISLFSNSYVVYEAQVVRYFLQSLVTLVFL 540
           SMCHKALQIRISIKSMLSAKVIGPILVIIHSISLFSNSYVVYEAQVVRYFLQSLVTLVFL
Sbjct: 481 SMCHKALQIRISIKSMLSAKVIGPILVIIHSISLFSNSYVVYEAQVVRYFLQSLVTLVFL 540

Query: 541 EKLRSTALRPRKPFKLNFLWKFVNQDQNLIIFTLIMVGLRSEPIFHRCREEEVGCDTYYP 600
           EKLRSTALRPRKPFKLNFLWKFVNQDQNLIIFTLIMVGLRSEPIFHRCREEEVGCDTYYP
Sbjct: 541 EKLRSTALRPRKPFKLNFLWKFVNQDQNLIIFTLIMVGLRSEPIFHRCREEEVGCDTYYP 600

Query: 601 SRQAGSLTRDAQVVRLLFALGSLAVANLSVFKYYGLRDTKSQIESNSKRSSETIRILSAT 660
           SRQAGSLTRDAQVVRLLFALGSLAVANLSVFKYYGLRDTKSQIESNSKRSSETIRILSAT
Sbjct: 601 SRQAGSLTRDAQVVRLLFALGSLAVANLSVFKYYGLRDTKSQIESNSKRSSETIRILSAT 660

Query: 661 SWLHIAIIVLHSVFASLTHDVSRANLSAHSLSVISLICAVLAWREGNSAICAHFLLMPVY 720
           SWLHIAIIVLHSVFASLTHDVSRANLSAHSLSVISLICAVLAWREGNSAICAHFLLMPVY
Sbjct: 661 SWLHIAIIVLHSVFASLTHDVSRANLSAHSLSVISLICAVLAWREGNSAICAHFLLMPVY 720

Query: 721 ILFGDGLIPAIIIFIAVSVLIAEFVSREFIASTIALLIPLGFYHLGHSPVISSIPWNAAF 780
           ILFGDGLIPAIIIFIAVSVLIAEFVSREFIASTIALLIPLGFYHLGHSPVISSIPWNAAF
Sbjct: 721 ILFGDGLIPAIIIFIAVSVLIAEFVSREFIASTIALLIPLGFYHLGHSPVISSIPWNAAF 780

Query: 781 VGIPGGTALRVLPALFVLFHLNFSAISSIFVISSESESSQKMSAPNTAWTLTETLVLMTI 840
           VGIPGGTALRVLPALFVLFHLNFSAISSIFVISSESESSQKMSAPNTAWTLTETLVLMTI
Sbjct: 781 VGIPGGTALRVLPALFVLFHLNFSAISSIFVISSESESSQKMSAPNTAWTLTETLVLMTI 840

Query: 841 RATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIVFIFSANFFLIYRQFFGEKFKNSEAK 900
           RATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIVFIFSANFFLIYRQFFGEKFKNSEAK
Sbjct: 841 RATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIVFIFSANFFLIYRQFFGEKFKNSEAK 900

Query: 901 INKLH 905
           INKLH
Sbjct: 901 INKLH 905
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  607 bits (1550), Expect = e-172
 Identities = 205/664 (30%), Positives = 315/664 (46%), Gaps = 93/664 (14%)

Query: 4   IIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQ---------PGQTCWMKQQ 54
           ++ +  V       + +F +GFLL R E+ ++SSC +                 CWM  +
Sbjct: 15  LLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGACWMPSR 74

Query: 55  YQRVILILVDALRYDFLIPIDENTKKSKE-EWYYRGQMKNIEKLV--KSGNVSIGTLLAD 111
           + RV+L+L+DALR+DF  P   +          + G++ ++++++  +  +  +     D
Sbjct: 75  FSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLYRSQVD 134

Query: 112 PPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSL 171
           PPTTT+QRLKALTTG+LPTFIDAG NF+  A++ ED+ + Q    G+ V  +GDDTW  L
Sbjct: 135 PPTTTMQRLKALTTGSLPTFIDAGSNFASHAIV-EDNVIQQLNSAGRRVVFMGDDTWRDL 193

Query: 172 FPNQFSKTAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSII 231
           FP  FS+   + SF++ DL+TVD+ I                     L   +   +  ++
Sbjct: 194 FPGAFSQAFFFSSFNVRDLHTVDNGILEH------------------LYPTLDGGSWDVL 235

Query: 232 IAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DHGMTSTGDHG 284
           IAHFLGVDHCGHK GP HP MA  L +MD++I   IE +++D       DHGMT  GDHG
Sbjct: 236 IAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLENDTLLVVAGDHGMTMNGDHG 295

Query: 285 GESENEIRAGILVHSKKHQII--LPERP--IHQIDIVPTISLLMGLPIPFSNLGTVITQL 340
           G+SE E+ A + ++S         PE P  I Q+ +VPT++LL+GLPIPF N G V+ +L
Sbjct: 296 GDSELEVSAALFLYSPTALFPSVPPEEPEVIPQVSLVPTLALLLGLPIPFGNTGEVMAEL 355

Query: 341 FT-------RDLWEIARQMMGFVWQDSVGIFAETYAAQK---NFGELH------------ 378
           F+            +A+     +    V  F  TY+A        ELH            
Sbjct: 356 FSGGSDSSHPHSSALAQVSALHINAQQVSRFLHTYSAATQDLQVKELHRLQTLFSKASAR 415

Query: 379 -SHTIRDSNTMEEQLDTM-SRIQTLLR-------VSWTQFDDAYINAGIFSLVEAIMFLI 429
             H +RD    E  L T+ +  Q  LR        SW +F    +  G   L  A +  +
Sbjct: 416 YQHFLRDPQEAEAALSTLTAEFQQFLRGARALCIESWARFSLVRMAGGAALLAAACLLCL 475

Query: 430 TNEVMSL-------EWIIYRTGCGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSIISM 482
               +++         ++     GL    L    + + GS   L+++  AV+   S++  
Sbjct: 476 LASQLAVAPGFLFRPLLLIPVAWGLTWTILYAGVSVTTGSKIDLVVLG-AVAAAGSLLPF 534

Query: 483 CHKALQIRISIKSMLSAKVIGP----ILVIIHSISLFSNSYVVYEAQVVRYFLQSLVTLV 538
             KA   R S K  L+  +  P    IL++I   + FS+S+ V EA+   + L SLV  +
Sbjct: 535 LWKAWVSRGS-KRPLAPLLPVPRPVLILLLIRLATFFSDSFFVVEARATPFLLGSLVFFL 593

Query: 539 FLEKLRSTALRPRKPFKLNFLWKFV-------NQDQNLIIFTLIMVGLRSEPIFHRCREE 591
             +      L P KP  ++ L           +    L +   +++  R   +FHRC EE
Sbjct: 594 VAQLHWEGQLLPPKPLTMSRLGSSAPTAPPRHSGAHALWLGIGLLLFTRLAGLFHRCPEE 653

Query: 592 EVGC 595
              C
Sbjct: 654 TPAC 657
 Score =  110 bits (274), Expect = 1e-22
 Identities = 28/83 (33%), Positives = 38/83 (45%), Gaps = 9/83 (10%)

Query: 752 STIALLIPLGFYHLGHSPVISSIPWNAAFVGIPGG-TALRVLPALFV-----LFHLNFSA 805
           S   LL    FY  GH PV S+I W+AAFVG P G  +   LPAL V       HL F+ 
Sbjct: 902 SAWVLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLLFAV 961

Query: 806 ISSIFVI-SS--ESESSQKMSAP 825
              + ++     E +  ++    
Sbjct: 962 GCPLLLLWPFLCERQGPKRRQPL 984
 Score = 88.4 bits (217), Expect = 5e-16
 Identities = 22/50 (44%), Positives = 29/50 (58%)

Query: 826  NTAWTLTETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIV 875
                   + L ++  +     L +SI RRHLMVWK+FAPKFIFE +  IV
Sbjct: 1020 ALLQLGLKYLFILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIV 1069
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  601 bits (1533), Expect = e-170
 Identities = 172/670 (25%), Positives = 289/670 (42%), Gaps = 113/670 (16%)

Query: 3   SIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILIL 62
            II ++ ++I   +++  F  GFLL R  + + SS ++          +  ++ + ++++
Sbjct: 35  YIILLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSK-------LPPRFNKAVILV 87

Query: 63  VDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTL---LADPPTTTLQR 119
           +DALR+DF IP++E    S     Y   + ++     S   +   L   +ADPPTTTLQR
Sbjct: 88  IDALRFDFAIPVNE--SHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQR 145

Query: 120 LKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF-PNQFSK 178
           LK LTTG+LPTFIDAG NF    VI ED+F+ Q     K V   GDDTW++LF P   + 
Sbjct: 146 LKGLTTGSLPTFIDAGSNF-DGTVIEEDNFLKQLHLANKTVKFAGDDTWMALFHPFLSND 204

Query: 179 TAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
           +   +S ++ DL+TVD+ +             +  F   + QD+       ++I H LG+
Sbjct: 205 SFPLESLNVWDLDTVDNGV-------------MDYFHDHLQQDK----EWDVMIGHMLGI 247

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DHGMTSTGDHGGESENEI 291
           DH GHK+GP H  M +   ++D+ I   ++++  D       DHGM  TG+HGG+S +E+
Sbjct: 248 DHVGHKYGPDHFTMREKQIQVDQFIDWILKSIDDDTLLVILGDHGMDHTGNHGGDSIDEL 307

Query: 292 RAGILVHSKKHQIILPER--------------PIHQIDIVPTISLLMGLPIPFSNLGTVI 337
            + + ++SKK  +   +                + QID+V +++LLMG PIPF+NLG  I
Sbjct: 308 ESTLFLYSKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLGWPI 367

Query: 338 TQLFTRD-LWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDSNTME-EQLDTM 395
            ++   D  W           Q         +   +    L  +      T + E+   +
Sbjct: 368 DEIARNDREWSQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKL 427

Query: 396 -----SRIQTLLRVSWTQFDDAYINAGIFSLVEAIMFLITNEVM------------SLEW 438
                          W +FD   I  GI  L  +++ LI+   +             +  
Sbjct: 428 GHKYQKVFLQTCEELWAKFDYYSIATGITLLATSLVLLISITKLIPSIVVNQMVPEFVPG 487

Query: 439 IIYRTGCGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSII----------SMCHKALQ 488
           II       L    +        S       TL  + +  II          +    A++
Sbjct: 488 IIIMVLVTNLCFHGI-FYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRYNFIWIAMR 546

Query: 489 IRISIKSMLSAKVIGPILVIIHSISLFSNSYVVYEAQVVRYFLQ-----SLVTLVFLEKL 543
           +  ++    S   I  + +IIH++   SNS+ ++E ++V + L      +L   VFL K 
Sbjct: 547 LGETLADYWS--RIAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLYEFVFLPKR 604

Query: 544 RS-TALRPRK------------PFKLN-------FLWKFVNQDQNLIIFTLIMVGLRSEP 583
           +S TAL                P   N          + +    +     ++++  R   
Sbjct: 605 QSTTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGGYHS----AVLIIFTRLAS 660

Query: 584 IFHRCREEEV 593
           +   CREE+ 
Sbjct: 661 MITICREEQG 670
 Score =  192 bits (484), Expect = 2e-47
 Identities = 33/129 (25%), Positives = 53/129 (40%), Gaps = 7/129 (5%)

Query: 753 TIALLIPLGFYHLGHSPVISSIPWNAAFVGIPGGTALRVLPALFVLFHLNFSAI--SSIF 810
            + LL    F+  GH   I S+ W+  F+ +             +L       +   S+ 
Sbjct: 863 ALGLLSYQHFFTTGHQATIPSVQWDIGFM-LSEKVTFPFTQIAIILNTFGPHILVSLSVA 921

Query: 811 VISSESESSQKMSAPNTAWTLTETLVLMTIRATLTCLVSSI----HRRHLMVWKIFAPKF 866
           +++  S+    +        +     ++    T+ CL S I     RRHLMVWKIF P+F
Sbjct: 922 LLTLWSQPPDVLKPQTLLGRIVSNCGILLTYNTILCLSSFIWVTHFRRHLMVWKIFCPRF 981

Query: 867 IFECILTIV 875
           IF  +  IV
Sbjct: 982 IFASLSLIV 990
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  542 bits (1384), Expect = e-153
 Identities = 189/691 (27%), Positives = 311/691 (44%), Gaps = 127/691 (18%)

Query: 3   SIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMK---------- 52
            +  ++ ++  I   + +F  GFLL R      S+C      P     +           
Sbjct: 5   YLFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIFKD 64

Query: 53  ---------QQYQRVILILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLV--KSG 101
                     Q  +VI+++VDAL+Y+F +        + +   Y  ++  +++L+     
Sbjct: 65  VNASSNLCLPQKSKVIVLVVDALKYEFGL----YRANATDPLPYENKLVVLQELLQQNPD 120

Query: 102 NVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVT 161
           +  +    ADPPTTTLQRLK LTTG+LPTFID G NF+    I+ED+ + Q  +    V 
Sbjct: 121 HARLMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFAS-PEINEDNIIDQIVKNDLPVV 179

Query: 162 LLGDDTWLSLFPNQFSKTAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQD 221
            LGD TW  L+P++F ++ +Y SFDI DL++VD++I + +                    
Sbjct: 180 FLGDSTWTDLYPHRFKRSYSYPSFDIFDLDSVDNEILKHLP------------------K 221

Query: 222 EMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------D 274
           E+ + +  +++AHFLGVDHCGHK GP H  MA  L +M+ +I   +  M +D       D
Sbjct: 222 ELESKDWQVLVAHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAMDNDTTLLVMGD 281

Query: 275 HGMTSTGDHGGESENEIRAGILVHSKKHQI-----ILPERPIHQIDIVPTISLLMGLPIP 329
           HGMT++GDHGG++++E  A +  +SK+H+            + QID+VPT++ ++G+PIP
Sbjct: 282 HGMTASGDHGGDTDDETNALLFAYSKQHRFYGNDSGSDSEMLQQIDLVPTLATILGVPIP 341

Query: 330 FSNLGTV--------------ITQLFTRDLWEIARQMMGFVWQ----------------D 359
           +SNLG V                Q      W+ A+Q+  + +Q                 
Sbjct: 342 YSNLGLVNFNIVPDLRVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRTFNVEQMDHL 401

Query: 360 SVGIFAETYAAQKNFGELH-SHTIRDSNTMEEQLDTMSRIQTLLRVSWTQFDDAYINAGI 418
                  T+  Q  + E+     +RD NT       +  I    R  W +FD   ++ G+
Sbjct: 402 ETEFILLTHRVQTVYNEVAFKSFVRDLNT------NLRDILGTCREIWVRFDPTQMSQGL 455

Query: 419 FS----------------LVEAIMFLITNEVMSLEWIIYRTGC-GLLQAALLTDKTDSDG 461
                               +        EV  +  I    G  G       + KT+  G
Sbjct: 456 LFTFLPLFFIFLVVNNSRPADFPHIFKAKEVFYVYLINLAAGVFGYRYFKTFSFKTEEQG 515

Query: 462 SARTLLLMTLAVSCLSSIISMCHKALQIRISIKSMLSA-KVIGPI---LVIIHSIS-LFS 516
                    +  + +SS + +    L+   SI +  SA K  G +   L++  S++  FS
Sbjct: 516 --------VIFFTAISSAVILAFHTLRHWTSIATNWSAVKRFGHMPTRLLLFGSMAVFFS 567

Query: 517 NSYVVYEAQVVRYFLQSLVTLVFLEKLRSTA-LRPRKPFKLNFLWKFVNQDQNLIIFTLI 575
           NS+V+ EA+++ Y L + + L+  E LR +A L  R  FK +   +       LI+ +++
Sbjct: 568 NSFVIQEAKILSYLLAAAILLLSHELLRLSARLDFRTKFKASQFLRST--ALRLILASVL 625

Query: 576 MVGL-RSEPIFHRCREEEVGCDTYYPSRQAG 605
            + L R      RCREE+  C  +  +  AG
Sbjct: 626 AICLIRFAYTLFRCREEQGNCSDFVNTGGAG 656
 Score = 83.7 bits (205), Expect = 1e-14
 Identities = 21/46 (45%), Positives = 29/46 (62%)

Query: 830  TLTETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIV 875
              T+  +L  ++     L  +IH RHLMVWKIFAP+FI+E + T V
Sbjct: 1000 LATQFFMLQGLKIFCAMLACTIHCRHLMVWKIFAPRFIYEALATFV 1045
 Score = 40.5 bits (94), Expect = 0.13
 Identities = 17/50 (34%), Positives = 21/50 (42%), Gaps = 2/50 (4%)

Query: 754 IALLIPLGFYHLGHSPVISSIPWNAAFVGIPGGT--ALRVLPALFVLFHL 801
             LL    F+   H   +S I W AAFVG   G   +  V  AL +L   
Sbjct: 875 WFLLAHFCFFATSHQTTLSQIEWRAAFVGRTTGIGQSNLVSGALVILNTF 924
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  502 bits (1280), Expect = e-140
 Identities = 160/645 (24%), Positives = 268/645 (40%), Gaps = 102/645 (15%)

Query: 3   SIIRILLVSINILL---ALFIFQNGFLLKRQEILSKSSCSDAHAQPGQ-----TCWMKQQ 54
            I   +  +I ++     L  F +GFLL+R  +   S C +  A   +      CW  + 
Sbjct: 21  YIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPKI 80

Query: 55  YQRVILILVDALRYDFLIPIDENTKKSKEEWYYRGQ-MKNIEKLVKSGNVSIGTLLADPP 113
           ++R +++++DALRYDFLIP ++        +Y+          ++   N  +   +AD P
Sbjct: 81  FERAVIVIIDALRYDFLIPYND------SNYYHNAFTTPYETSVLHPENSYLTQFIADAP 134

Query: 114 TTTLQRLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFP 173
           TTT QRLK LTTG+LPTFID G NF+    I ED+ + Q   L K + LLGDDTW  LF 
Sbjct: 135 TTTSQRLKGLTTGSLPTFIDLGSNFA-GTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFH 193

Query: 174 N--QFSKTAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSII 231
           +    + +    SF++ DL+ VD+K+ + +                   D + ++N  ++
Sbjct: 194 DYLNETLSQPAFSFNVPDLHGVDNKVNQYV------------------FDYIKDANFDVL 235

Query: 232 IAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DHGMTSTGDHG 284
           IAH+LGVDH GH+ GP HP M D L +MDR + + ++ +          DHGM + G+HG
Sbjct: 236 IAHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLLDDSTLLIVMGDHGMDNKGNHG 295

Query: 285 GESENEIRAGILVHSKKHQIILPERP-----IHQIDIVPTISLLMGLPIPFSNLGTVITQ 339
           G+S +EI + + ++SKK      ++P      +Q+D+VPT+SLL+G PIP+ NLGT+I +
Sbjct: 296 GDSFDEINSVLWMYSKKPTFGYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPE 355

Query: 340 ---LFTRDLWEIAR-----QMMGFVWQDSVGIF-AETYAAQKNFGELHSHTIRDSNTMEE 390
               +  +    A+     Q+  F  +  +      + +  KN          D +   +
Sbjct: 356 PFYYYGDEYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNNNSYLDQYFLDFDYARD 415

Query: 391 QLDTMSRIQTLLRVSWTQFDDAYINAGIFSLVEAIMFLITNEVMSLEWIIYRTG------ 444
                          W +F    +  G   L+     L          I   +       
Sbjct: 416 AFSYFK-------AIWAEFSLFPMIIGFLLLIIGGFNLALLMQDK-SVIFRMSANMAPSV 467

Query: 445 --CGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSIISMCHKALQIRISIKSMLSAKVI 502
             C  +   L+    +          + L      S   + +        +       V 
Sbjct: 468 MKCLPVCLILILANNELHSPFPAEFYVLL-----PSFYILLN---SFNQKLMEYFKGFVK 519

Query: 503 GPILVII----HSISLFSNSYVVYEAQVVRYFLQSLVTLVFLEKLRSTALRPRKPFKLNF 558
                I     H  S  SNS+ V+E ++  + + ++  ++F +     +           
Sbjct: 520 LDYFSIFITFLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCKCFSEMS---------PL 570

Query: 559 LWKFVNQDQNLIIFTLIMVGLRSEPIFHRCREEEVG--CDTYYPS 601
                      I+  +I            CREE+      TY  +
Sbjct: 571 FACSTYSALAFILLQVI------SSYVTNCREEQGAFCVSTYIST 609
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  467 bits (1191), Expect = e-130
 Identities = 159/491 (32%), Positives = 235/491 (47%), Gaps = 85/491 (17%)

Query: 4   IIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQ---------PGQTCWMKQQ 54
           ++ +  V       + +F +GFLL R E+ + SSC +                 CWM  +
Sbjct: 7   LLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASR 66

Query: 55  YQRVILILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPT 114
           + RV+L+L+DALR+DF  P   +                    ++  +  +     DPPT
Sbjct: 67  FSRVVLVLIDALRFDFAQPQHSHRILE----------------IQPHHARLYRSQVDPPT 110

Query: 115 TTLQRLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPN 174
           TT+QRLKALTTG+LPTFIDAG NF+  A++ ED+ + Q    G+ V  +GDDTW  LFP 
Sbjct: 111 TTMQRLKALTTGSLPTFIDAGSNFASHAIV-EDNLIKQLTSAGRRVVFMGDDTWKDLFPG 169

Query: 175 QFSKTAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAH 234
            FSK   + SF++ DL+TVD+ I                     L   M +    ++IAH
Sbjct: 170 AFSKAFFFPSFNVRDLDTVDNGILEH------------------LYPTMDSGEWDVLIAH 211

Query: 235 FLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DHGMTSTGDHGGES 287
           FLGVDHCGHK GP HP MA  L +MD++I   +E +++D       DHGMT+ GDHGG+S
Sbjct: 212 FLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDHGMTTNGDHGGDS 271

Query: 288 ENEIRAGILVHSKKHQII--LPERP--IHQIDIVPTISLLMGLPIPFSNLGTVITQLFT- 342
           E E+ A + ++S         PE P  I Q+ +VPT++LL+GLPIPF N+G V+ +LF+ 
Sbjct: 272 ELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSG 331

Query: 343 -----RDLWEIARQMMGFVWQDSVGIFAETYAAQK---NFGELH-------------SHT 381
                     +A+     +    V  F  TY+A        ELH                
Sbjct: 332 GEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWL 391

Query: 382 IRDSNTMEEQLDT-MSRIQTLLR-------VSWTQFDDAYINAGIFSLVEAIMFLITNEV 433
           ++     E  L T ++ +Q  LR        SW +F    +         A +  +   +
Sbjct: 392 LQSPKGAEATLPTVIAELQQFLRGARAMCIESWARFSLVRMAGAKNLWYGACVAALVALL 451

Query: 434 MSLEWIIYRTG 444
            ++   + R G
Sbjct: 452 AAVRLWLRRYG 462
 Score =  119 bits (296), Expect = 3e-25
 Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 9/83 (10%)

Query: 752 STIALLIPLGFYHLGHSPVISSIPWNAAFVGIPGG-TALRVLPALFV-----LFHLNFSA 805
           S  AL+    FY  GH PV  +I W+AAFVG P G  +   LPAL V       HL F+ 
Sbjct: 743 SAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAV 802

Query: 806 ISSIFVI-SS--ESESSQKMSAP 825
              + ++     ES+  +K   P
Sbjct: 803 GCPLLLLWPFLCESQGLRKRQQP 825
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  435 bits (1107), Expect = e-120
 Identities = 101/526 (19%), Positives = 174/526 (32%), Gaps = 89/526 (16%)

Query: 9   LVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQ-QYQRVILILVDALR 67
            +  +I + L +  + F +     L        H  P Q    ++   +R+ +I  D LR
Sbjct: 5   FLIASITVHLVLIYSIFDVYYTSPL-------VHGIPPQFINSQEAPAKRIFIISADGLR 57

Query: 68  YDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGT 127
           YD                 Y  +   +  ++       G   +  PT +     A+  G 
Sbjct: 58  YDTFN-------------KYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGI 104

Query: 128 LPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF---PN--QFSKTAAY 182
                     +  + V  +  F   +        + G    ++LF   PN   FS +A  
Sbjct: 105 TEDISAVAKGWKKNPVQFDSVFNRSSYS-----WMWGSPDIVNLFDDLPNAESFSYSADE 159

Query: 183 DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCG 242
           + F   D + +D     K  F  + N +        L D+M     SI   H LG+D  G
Sbjct: 160 EDFASKDASNLD-----KWVFEHFENFLETAKTDEALNDKM-REQKSIFFLHLLGIDTNG 213

Query: 243 HKFGPSHPVMADTLRKMDRIIGQTIET------------MKSDDHGMTSTGDHGGESENE 290
           H   P      D ++ +D  I +                + + DHGMT  G HG  S++E
Sbjct: 214 HGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDE 273

Query: 291 IRAGILVHSKKHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLFTRDLWEIAR 350
           +    +      +   P+  ++QID+ P IS L+G PIP +++G +  Q+          
Sbjct: 274 VLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMM--------- 324

Query: 351 QMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDSNTMEEQLDTMSRIQTLLRVS--WTQ 408
                   +S G   E  A + NF +L    I   N    +L    + +     +    +
Sbjct: 325 --------NSKGSSYEFKAIEANFKQLKEQIIFLKNAKSRRLW-FRQFEKFGDKAMESLR 375

Query: 409 FDDAYINAGIFSLVEAIMFLITNEVMSLEWIIYRTGCGLLQAALLTDKTDSDGSARTLLL 468
              A +       V   +F     +M    + Y                          +
Sbjct: 376 TTLAQLGRDRRFSVATSLFADNAHLMKEAIVFY--------------------HRYDRQM 415

Query: 469 MTLAVSCLSSIISMCHKALQIRISIKSMLSAKVIGPILVIIHSISL 514
           +  AVSC          +     + K  LS  V   + +I  + SL
Sbjct: 416 LGAAVSCSFVAWIALVVSFLHNSTSKENLSLLVPHHLFIIPLACSL 461
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  417 bits (1062), Expect = e-115
 Identities = 90/557 (16%), Positives = 169/557 (30%), Gaps = 99/557 (17%)

Query: 9   LVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDALRY 68
           L+++ +L  LF   + F +     L        H             +R+ LI+ D LR 
Sbjct: 9   LLAVGVLFHLFYLWSIFDIYFISPL-------VHGMSPYQSTPTPPAKRLFLIVGDGLRA 61

Query: 69  DFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTL 128
           D       +    K E+        I  LV + N + G      PT +     A+  G  
Sbjct: 62  DTTFDKVTHPVSGKTEF----LAPFIRSLVMN-NATYGISHTRMPTESRPGHVAMIAGFY 116

Query: 129 PTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF------PN---QFSKT 179
                    +  +  ++ DSF  Q+     +    G    L +F      PN    +   
Sbjct: 117 EDVSAVTKGWKSNP-VNFDSFFNQST----HTYSFGSPDILPMFKDGASDPNKVDTWMYD 171

Query: 180 AAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVD 239
             ++ F  + +  +D  + R +      +++          D  +  + ++   H LG D
Sbjct: 172 HTFEDFTQSSI-ELDAFVFRHL------DQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCD 224

Query: 240 HCGHKFGPSHPVMADTLRKMDRIIGQTIE------------TMKSDDHGMTSTGDHGGES 287
             GH + P      D ++ +D  I   I+             + + DHGM++ G HG   
Sbjct: 225 TAGHSYRPYSAEYYDNVKYIDDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGH 284

Query: 288 ENEIRAGILVHSKKHQIILPE-------------------RPIHQIDIVPTISLLMGLPI 328
            N  R  ++         +                       + Q DI   +S L+G+  
Sbjct: 285 PNNTRTPLVAWGAGLNKPVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNY 344

Query: 329 PFSNLGTVITQLFTRDLWEIARQMMGFVWQDSVGIFAETY---AAQKNFGELHSHTIRDS 385
           P +++G +          +       +    S+               F     +     
Sbjct: 345 PKNSVGELPIAYIDGKESDKLA--ALYNNARSILEQYLVKQDEVIDSQFF-YKEYFKFVE 401

Query: 386 NTMEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFSLVEAIMFLITNEVMSLEWIIYRTGC 445
            +    L+ +  +               I+ G   L E     +T E+M +         
Sbjct: 402 KSHSHYLEEIETLIQ------------RISEGENYL-EQEAITLTEELMQITLEGLHYLT 448

Query: 446 GLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSIISMCHKALQIRISI----KSMLSAKV 501
                 + T  T           +        S I    K+  +   I     S LS  V
Sbjct: 449 TYNWRFIRTIVTFG--------FVGWIF---FSFIIFL-KSFILENVIDDQKASPLSHAV 496

Query: 502 IGPILVIIHSISLFSNS 518
            G I ++++ I  + +S
Sbjct: 497 FGSIGILLNWILFYQHS 513
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  409 bits (1041), Expect = e-112
 Identities = 72/421 (17%), Positives = 131/421 (31%), Gaps = 73/421 (17%)

Query: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDAL 66
           +L  ++ +L+    F + F +     L        H    Q   +    +R++L + D L
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPL-------VHGMTPQFTPLPPPAKRLVLFVADGL 54

Query: 67  RYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTG 126
           R D L  +DE+            +   I  ++              PT +     AL  G
Sbjct: 55  RADTLYELDEDGNS---------RAPFIRNVIMHEGSWGV-SHTRVPTESRPGHVALIAG 104

Query: 127 TLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAAY 182
                      +  +  +  DS   ++    K     G    L +F          T +Y
Sbjct: 105 FYEDVSAVAKGWKENP-VEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSY 159

Query: 183 ----DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
               + F  +D   +D        F K  +          L  ++ N    +   H LG+
Sbjct: 160 DAQREDFGAHDATKLD-----TWVFDKVKDFFDAARNNQSLFTKV-NEEKVVFFLHLLGI 213

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIET-------------MKSDDHGMTSTGDHGG 285
           D  GH   PS     D ++K+D  + + +               + + DHGMT  G HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 286 ESENEIRAGILVHSKKHQIIL--------------------PERPIHQIDIVPTISLLMG 325
              +E     +      +                         R ++Q DI P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 326 LPIPFSNLGTVITQLFTRDLWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDS 385
           +P P +++G +            A  M    + ++V I  +         E     +   
Sbjct: 334 VPFPLNSVGILPVGYLNNTGLFKAESM----FTNAVQILEQFKVKMTQKKEATLPFLFTP 389

Query: 386 N 386
            
Sbjct: 390 F 390
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  405 bits (1030), Expect = e-111
 Identities = 76/434 (17%), Positives = 137/434 (31%), Gaps = 76/434 (17%)

Query: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDAL 66
           +L  ++ +L+    F + F +     L        H    Q   +    +R++L + D L
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTSPL-------VHGMTPQFTPLPPPAKRLVLFVADGL 54

Query: 67  RYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTG 126
           R D L  +DE+            +   I  ++              PT +     AL  G
Sbjct: 55  RADTLYELDEDGNS---------RAPFIRNVIMHEGSWGV-SHTRVPTESRPGHVALIAG 104

Query: 127 TLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAAY 182
                      +  +  +  DS   ++    K     G    L +F          T +Y
Sbjct: 105 FYEDVSAVAKGWKENP-VEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSY 159

Query: 183 ----DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
               + F  +D   +D        F K  +          L  ++ N    +   H LGV
Sbjct: 160 DAQREDFGAHDATKLD-----TWVFDKVKDFFDAARNNQSLFTKV-NEEKVVFFLHLLGV 213

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIET-------------MKSDDHGMTSTGDHGG 285
           D  GH   PS     D ++K+D  + + +               + + DHGMT  G HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 286 ESENEIRAGILVHSKKHQIIL--------------------PERPIHQIDIVPTISLLMG 325
              +E     +      +                         R ++Q DI P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 326 LPIPFSNLGTVITQLFTRDLWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDS 385
           +P P +++G +            A  M    + ++V I  +         E     +   
Sbjct: 334 VPFPLNSVGILPVGYLNNTGLFKAESM----FTNAVQILEQFKVKMTQKKEATLPFLFTP 389

Query: 386 N---TMEEQLDTMS 396
               +  +QLD + 
Sbjct: 390 FKLLSDSQQLDILR 403
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  400 bits (1019), Expect = e-110
 Identities = 75/434 (17%), Positives = 137/434 (31%), Gaps = 76/434 (17%)

Query: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDAL 66
           +L  ++ +L+    F + F +     L        H    Q   +    +R++L + D L
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPL-------VHGMTPQFTPLPPPAKRLVLFVADGL 54

Query: 67  RYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTG 126
           R D L  +DE+            +   I  ++              PT +     AL  G
Sbjct: 55  RADTLYELDEDGNS---------RAPFIRNVIIHEGSWGV-SHTRVPTESRPGHVALIAG 104

Query: 127 TLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAAY 182
                      +  +  +  DS   ++    K     G    L +F          T +Y
Sbjct: 105 FYEDVSAVAKGWKENP-VEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSY 159

Query: 183 ----DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
               + F  +D   +D        F K  +          L  ++ N    +   H LG+
Sbjct: 160 DAQREDFGAHDATKLD-----TWVFDKVKDFFDAARNNQSLFTKV-NEEKVVFFLHLLGI 213

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIET-------------MKSDDHGMTSTGDHGG 285
           D  GH   PS     D ++K+D  + + +               + + DHGMT  G HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 286 ESENEIRAGILVHSKKHQIIL--------------------PERPIHQIDIVPTISLLMG 325
              +E     +      +                         R ++Q DI P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 326 LPIPFSNLGTVITQLFTRDLWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDS 385
           +P P +++G +            A  M    + ++V I  +         E     +   
Sbjct: 334 VPFPLNSVGILPVGYLNNTGLFKAESM----FTNAVQILEQFKVKMTQKKEATLPFLFTP 389

Query: 386 N---TMEEQLDTMS 396
               +  +QLD + 
Sbjct: 390 FKLLSDSQQLDILR 403
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  398 bits (1012), Expect = e-109
 Identities = 76/434 (17%), Positives = 137/434 (31%), Gaps = 76/434 (17%)

Query: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDAL 66
           +L  ++ +L+    F + F +     L        H    Q   +    +R++L + D L
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTSPL-------VHGMTPQFTPLPPPAKRLVLFVADGL 54

Query: 67  RYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTG 126
           R D L  +DE+            +   I  ++              PT +     AL  G
Sbjct: 55  RADTLYELDEDGNS---------RAPFIRNVIMHEGSWGV-SHTRVPTESRPGHVALIAG 104

Query: 127 TLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAAY 182
                      +  +  +  DS   ++    K     G    L +F          T +Y
Sbjct: 105 FYEDVSAVAKGWKENP-VEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSY 159

Query: 183 ----DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
               + F  +D   +D        F K  +          L  ++ N    +   H LGV
Sbjct: 160 DAQREDFGAHDATKLD-----TWVFDKVKDFFDAARNNQSLFTKV-NEEKVVFFLHLLGV 213

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIET-------------MKSDDHGMTSTGDHGG 285
           D  GH   PS     D ++K+D  + + +               + + DHGMT  G HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 286 ESENEIRAGILVHSKKHQIIL--------------------PERPIHQIDIVPTISLLMG 325
              +E     +      +                         R ++Q DI P ++ L+G
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQNVSAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIG 333

Query: 326 LPIPFSNLGTVITQLFTRDLWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDS 385
           +P P +++G +            A  M    + ++V I  +         E     +   
Sbjct: 334 VPFPLNSVGILPVGYLNNTGLFKAESM----FTNAVQILEQFKVKMTQKKEATLPFLFTP 389

Query: 386 N---TMEEQLDTMS 396
               +  +QLD + 
Sbjct: 390 FKLLSDSQQLDILR 403
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  377 bits (960), Expect = e-103
 Identities = 129/538 (23%), Positives = 213/538 (38%), Gaps = 112/538 (20%)

Query: 10  VSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMK--QQYQRVILILVDALR 67
           +S   LLA+ +F   F  ++  +   S        P Q   ++  + +Q+++ +++DALR
Sbjct: 9   LSCAQLLAILLFIFAFFPRKIVLTGISKQ-----DPDQDRDLQRDRPFQKLVFVIIDALR 63

Query: 68  YDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGT 127
            DFL   D           +          + +G     T  A+PPT TL RLK++TTG+
Sbjct: 64  SDFLF--DSQISHFNNVHQW----------LNTGEAWGYTSFANPPTVTLPRLKSITTGS 111

Query: 128 LPTFIDAGDNFSPDAVISE----DSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTA-AY 182
            P+FID   N + D   ++    DS++ Q  Q    +  +GDDTWL LFP Q+   A   
Sbjct: 112 TPSFIDLLLNVAQDIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPT 171

Query: 183 DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCG 242
            SF ++D   VD+ + R +    +                   +   + I H+LG+DH G
Sbjct: 172 HSFFVSDFTQVDNNVTRNLPGKLFQEW----------------AQWDVAILHYLGLDHIG 215

Query: 243 HKFGPSHPVMADTLRKMDRIIGQTIETM---KSD---------DHGMTSTGDHGGESENE 290
           HK GP    MA   ++MD I+    + +   + D         DHGM   G+HGG S  E
Sbjct: 216 HKDGPHSKFMAAKHQEMDSILKSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGE 275

Query: 291 IRAGILVHSKK-HQIILPE--------------------RPIHQIDIVPTISLLMGLPIP 329
             AG+L  S K  Q   PE                      + QIDIVPTI+ L G+PIP
Sbjct: 276 TSAGLLFLSPKLAQFARPESQVNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIP 335

Query: 330 FSNLGTVITQL--FTRDLWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDSNT 387
            +++G +I        +     ++    +W+ S               + H     D  T
Sbjct: 336 MNSVGIIIPDFLQLLPNKLASMKENFMHLWKLS---------------DHHGEVALDDFT 380

Query: 388 MEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFSLVEAIMFLITNEVMSLEWIIYRTGCGL 447
            E+    M  IQ  L  S T ++          L  A +  +   ++++  ++  +G   
Sbjct: 381 AEDIYTKMYTIQETLTKSATNYNYP-------LLTLAFVGFLIITIIAIYVLLRYSGPDF 433

Query: 448 LQA----------ALLTDKTDSDGSARTLLLMTL-----AVSCLSSIISMCHKALQIR 490
            Q           +++   +    S              A S +   +   +  + +R
Sbjct: 434 WQLRVSSLSVLLVSIILGVSTFASSFIEEEHQLWWWIVTAFSAVPLFVYRLNVLIIVR 491
 Score = 39.7 bits (92), Expect = 0.21
 Identities = 26/121 (21%), Positives = 45/121 (36%), Gaps = 5/121 (4%)

Query: 752 STIALLIPL--GFYHLGHSPVISSIPWNAAFVGIPGGTALRVLPALFVLFHLNFSAISSI 809
           S +  LI     F+  G +  IS+I    A+ G+     + V+  L  + +   +   S+
Sbjct: 686 SNLVSLILQNFTFFQFGGTNSISTIDLGNAYHGVSSDYNIYVVGILMSVANFAPAIYWSM 745

Query: 810 F--VISSESESSQKMSAPNTAWTLTETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFI 867
               I+  S  +Q          L        I  T       + R HL +W +F+PK  
Sbjct: 746 LPWSINYASIPAQVKLQTFIRSKLPAFTY-HCIFGTCLMTACVVLRFHLFIWSVFSPKLC 804

Query: 868 F 868
           +
Sbjct: 805 Y 805
>sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CHROMOSOME I
 pir||S62432 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 pir||T37638 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91096.1| (Z54308) putative major facilitator superfamily protein
           [Schizosaccharomyces pombe]
          Length = 758

 Score =  368 bits (935), Expect = e-100
 Identities = 125/530 (23%), Positives = 212/530 (39%), Gaps = 100/530 (18%)

Query: 10  VSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQR------VILILV 63
           +    +    +F  GF                H        M  Q+        V+ ++V
Sbjct: 8   IFWLQIFGSILFLLGFF--------------PHKNDSTGKAMSNQFSPPAVIDQVVFVMV 53

Query: 64  DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLV-KSGNVSIGTLLADPPTTTLQRLKA 122
           DALR DF+     N             M   + L+  S +    +  A  PT T+ RLKA
Sbjct: 54  DALRADFVFSKSHN-------------MPFTQSLLYNSTHGIGFSAFARSPTVTMPRLKA 100

Query: 123 LTTGTLPTFIDAGDNFSP----DAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSK 178
           LTTGT+P F+D   N +      ++ ++DS+VYQ     K +   GDDTWL LFP+ FSK
Sbjct: 101 LTTGTIPGFLDVLLNIAESDTGSSIEAQDSWVYQLNSFNKKIEFYGDDTWLKLFPSAFSK 160

Query: 179 TAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
                SF ++D   VD+ + R                   L   + +S    +I H+LGV
Sbjct: 161 FEGTTSFFVSDYTEVDNNVTRNF--------------DHALPSSLSHS-WDALILHYLGV 205

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS--------------DDHGMTSTGDHG 284
           DH GH +GPS P++   L ++D II +  + ++                DHGM   G+HG
Sbjct: 206 DHIGHLYGPSSPLLNIKLLEIDTIISRIYKYLQEYDEKTNTHSLIVLCGDHGMNEVGNHG 265

Query: 285 GESENEIRAGILVHSKKHQIILPERPI--------------HQIDIVPTISLLMGLPIPF 330
           G S  E  A + +    +++    +PI               Q+D+VPTI LL+G+PIP 
Sbjct: 266 GSSSGETTAALSLLFPSNELSHINKPILNMDDNPYSILERVEQVDVVPTICLLLGIPIPK 325

Query: 331 SNLG---TVITQLFTRDL-WEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDSN 386
            N+G   + +T+L+      ++A     F           T      F +       D N
Sbjct: 326 GNMGKVLSPVTELWKDTKTAKMAALSNLFQLSLLKNPSLTTSELSTQFQD------SDLN 379

Query: 387 TMEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFSL-VEAIMFLITNEVMSLEWIIYRTGC 445
            +   L+ +   Q+ +    + +    +   I  L   +I+ LI    +     +     
Sbjct: 380 DIRLALENL---QSQMVAQSSSYSLDRMLVAISILGACSILSLILFRNLYNYKELLAFAP 436

Query: 446 GLLQAALLTDKTDSDGSARTLLLMTLAVSCLS-SIISMCHKALQIRISIK 494
            ++Q  ++   +    S      +    + +S S++ + +   ++  S++
Sbjct: 437 FVVQNIIIVFSS----SFIEEEHVIWYFAAVSLSLLQLLNPKTRLAGSLQ 482
 Score = 44.0 bits (103), Expect = 0.011
 Identities = 23/110 (20%), Positives = 45/110 (40%), Gaps = 14/110 (12%)

Query: 762 FYHLGHSPVISSIPWNAAFVGIPGGTALRVLPALFVLFHLNFSAISSIFVISSESESSQK 821
           F+ LG+S  ++++  + A+ G+    +  +     +LF   F+      +          
Sbjct: 641 FFSLGNSNSLATVDLSQAYTGLD---SYNIFAVGILLFTSVFAGALWWCL---------- 687

Query: 822 MSAPNTAWTLTETLVLM-TIRATLTCLVSSIHRRHLMVWKIFAPKFIFEC 870
                      +T  +M +I  T  C+   I R HL VW +F+PK ++  
Sbjct: 688 HQPKRMMDRSVKTFWIMSSISLTFLCISCFIMRHHLFVWSVFSPKLLYNA 737
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  352 bits (894), Expect = 2e-95
 Identities = 81/387 (20%), Positives = 139/387 (34%), Gaps = 66/387 (17%)

Query: 9   LVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQ-QYQRVILILVDALR 67
            +  +I + L +  + F +     L        H  P Q    ++   +R+ +I  D LR
Sbjct: 5   FLIASITVHLVLIYSIFDVYYTSPL-------VHGIPPQFINSQEAPAKRIFIISADGLR 57

Query: 68  YDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGT 127
           YD                 Y  +   +  ++       G   +  PT +     A+  G 
Sbjct: 58  YDTFN-------------KYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGI 104

Query: 128 LPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF---PN--QFSKTAAY 182
                     +  + V  +  F   +        + G    ++LF   PN   FS +A  
Sbjct: 105 TEDISAVAKGWKKNPVQFDSVFNRSSYS-----WMWGSPDIVNLFDDLPNAESFSYSADE 159

Query: 183 DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCG 242
           + F   D + +D     K  F  + N +        L D+M     SI   H LG+D  G
Sbjct: 160 EDFASKDASNLD-----KWVFEHFENFLETAKTDEALNDKM-REQKSIFFLHLLGIDTNG 213

Query: 243 HKFGPSHPVMADTLRKMDRIIGQTIET------------MKSDDHGMTSTGDHGGESENE 290
           H   P      D ++ +D  I +                + + DHGMT  G HG  S++E
Sbjct: 214 HGNKPMSRQYIDNIKVVDSGIEKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDE 273

Query: 291 IRAGILVHSKKHQIILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQLFTRDLWEIAR 350
           +    +      +   P+  ++QID+ P IS L+G PIP +++G +  Q+          
Sbjct: 274 VLTPFVAWGAGVKQGGPKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMM--------- 324

Query: 351 QMMGFVWQDSVGIFAETYAAQKNFGEL 377
                   +S G   E  A + NF ++
Sbjct: 325 --------NSKGSSYEFKAIEANFKQV 343
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  330 bits (839), Expect = 6e-89
 Identities = 59/330 (17%), Positives = 102/330 (30%), Gaps = 50/330 (15%)

Query: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDAL 66
           +L  ++ +L+    F + F +     L        H    Q   +    +R++L + D L
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPL-------VHGMTPQFTPLPPPAKRLVLFVADGL 54

Query: 67  RYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTG 126
           R D L  +DE+            +   I  ++              PT +     AL  G
Sbjct: 55  RADTLYELDEDGNS---------RAPFIRNVIMHEGSWGV-SHTRVPTESRPGHVALIAG 104

Query: 127 TLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAAY 182
                      +  +  +  DS   +     K     G    L +F          T +Y
Sbjct: 105 FYEDVSAVAKGWKENP-VESDSLFNE----RKYTWSWGSPDILPMFAKGASGDHVYTYSY 159

Query: 183 ----DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
               + F  +D   +D        F K  +          L  ++ N    +   H LG+
Sbjct: 160 DAQREDFGAHDATKLD-----TWVFDKVKDFFDAARNNQSLFTKV-NEEKVVFFLHLLGI 213

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIET-------------MKSDDHGMTSTGDHGG 285
           D  GH   PS     D ++K+D  + + +               + + DHGMT  G HG 
Sbjct: 214 DTNGHAHRPSSREYKDNIKKVDDGVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGA 273

Query: 286 ESENEIRAGILVHSKKHQIILPERPIHQID 315
              +E     +      +         Q D
Sbjct: 274 GHPSETLTPFVTWGAGIKFPQ-NVSAQQYD 302
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  322 bits (817), Expect = 2e-86
 Identities = 68/435 (15%), Positives = 135/435 (30%), Gaps = 88/435 (20%)

Query: 9   LVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQ---PGQTCWMKQQYQRVILILVDA 65
           LV + + L      + F +  +  +        H     P +        +R++L++ D 
Sbjct: 46  LVVLGVALHAVYMLSIFDIYFKTPI-------VHGMDPVPPRFSE--PPAKRLVLLISDG 96

Query: 66  LRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTT 125
           LR D     DE           + +   +  ++K+     G   A PPT +     A+  
Sbjct: 97  LRADKFFEPDEEG---------KYRAPFLRNIIKN-QGRWGVSHARPPTESRPGHVAIIA 146

Query: 126 GTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAA 181
           G           +  +  +  DS   Q+    ++    G    + +F    P+    +  
Sbjct: 147 GFYEDPSAVTKGWKANP-VEFDSVFNQS----RHTFAFGSPDIIPIFCSALPHSTWNSYP 201

Query: 182 YDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHC 241
           ++     D  T D     +  F ++   +      P L  E+L+ +  ++  H LG D  
Sbjct: 202 HE---YEDFAT-DASFLDEWSFDQFEGLLNRSHADPKL-KELLHQDKLVVFLHLLGCDSN 256

Query: 242 GHKFGPSHPVMADTLRKMDRIIGQTIETMK------------SDDHGMTSTGDHGGESEN 289
           GH   P   +  + ++ +D+I  +    ++            + DHGM+  G HG     
Sbjct: 257 GHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPT 316

Query: 290 EIRAGILVHSKKHQIILP---------------------------------ERPIHQIDI 316
                ++      Q   P                                    ++Q DI
Sbjct: 317 NTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADI 376

Query: 317 VPTISLLMGLPIPFSNLGTVITQLFTRD---LWEIARQMMGFVWQDSVGIFAETYAAQKN 373
            P +S L+GLP P +++G +       +     E        +    +       +    
Sbjct: 377 APLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLF 436

Query: 374 FGE----LHSHTIRD 384
           F      +H      
Sbjct: 437 FKPFKPLVHHSFSLS 451
 Score =  267 bits (678), Expect = 5e-70
 Identities = 54/318 (16%), Positives = 108/318 (32%), Gaps = 48/318 (15%)

Query: 9   LVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQ---PGQTCWMKQQYQRVILILVDA 65
           LV + + L      + F +  +  +        H     P +        +R++L++ D 
Sbjct: 46  LVVLGVALHAVYMLSIFDIYFKTPI-------VHGMDPVPPRFSE--PPAKRLVLLISDG 96

Query: 66  LRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTT 125
           LR D     DE           + +   +  ++K+     G   A PPT +     A+  
Sbjct: 97  LRADKFFEPDEEG---------KYRAPFLRNIIKN-QGRWGVSHARPPTESRPGHVAIIA 146

Query: 126 GTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAA 181
           G           +  +  +  DS   Q+    ++    G    + +F    P+    +  
Sbjct: 147 GFYEDPSAVTKGWKANP-VEFDSVFNQS----RHTFAFGSPDIIPIFCSALPHSTWNSYP 201

Query: 182 YDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHC 241
           ++     D  T D     +  F ++   +      P L  E+L+ +  ++  H LG D  
Sbjct: 202 HE---YEDFAT-DASFLDEWSFDQFEGLLNRSHADPKL-KELLHQDKLVVFLHLLGCDSN 256

Query: 242 GHKFGPSHPVMADTLRKMDRIIGQTIETMK------------SDDHGMTSTGDHGGESEN 289
           GH   P   +  + ++ +D+I  +    ++            + DHGM+  G HG     
Sbjct: 257 GHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPT 316

Query: 290 EIRAGILVHSKKHQIILP 307
                ++      Q   P
Sbjct: 317 NTDTPLVAWGAGIQYPKP 334
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  316 bits (802), Expect = 1e-84
 Identities = 76/429 (17%), Positives = 145/429 (33%), Gaps = 77/429 (17%)

Query: 9   LVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDALRY 68
           L+ + IL  +   ++ F +     L        H     +       +R+ LI+ D LR 
Sbjct: 5   LLLLGILFHVVFLKSIFDIYFVTPL-------IHGMKQYSAGEAP-AKRLFLIVGDGLRP 56

Query: 69  DFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTL 128
           D L+         +E+ Y       +  ++++            PT +     AL  G  
Sbjct: 57  DKLLQPHSEKVIGEEQTY---AAPFLRSIIQNNGTFGV-SHTRVPTESRPGHVALIAGFY 112

Query: 129 PTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFP---------NQFSKT 179
                    +  +  ++ DS   Q+    ++    G +  L +F          + F  +
Sbjct: 113 EDVSAVTKGWKKNP-VNFDSVFNQS----RHTYSFGSEDILPMFSEGASDPSRVDTFMYS 167

Query: 180 AAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVD 239
           +  + F  N +      +  +  F +    +    E   L D ML+ +  +   H LG+D
Sbjct: 168 SELEDFSSNGI------VLDEWVFDRLDELLAQSLEDKELWD-MLHRDKIVFFLHLLGID 220

Query: 240 HCGHKFGPSHPVMADTLRKMDRIIGQTIETM-------------KSDDHGMTSTGDHGGE 286
             GH   P      + ++ +D  I + ++ M              + DHGM+  G HG  
Sbjct: 221 TIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDG 280

Query: 287 SENEIRAGILVHSKKHQIILPER-------------------PIHQIDIVPTISLLMGLP 327
           + +  R  I+      Q    E+                    I Q DI   +S L+GL 
Sbjct: 281 NLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLN 340

Query: 328 IPFSNLGTVITQLF---TRDLWEIARQMMGFV---------WQDSVGIFAETYAAQKNFG 375
            P +++G +        +R   E+A      +          +D   IF   Y+  +N+ 
Sbjct: 341 FPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYT 400

Query: 376 ELHSHTIRD 384
           E+ +     
Sbjct: 401 EVQASFYNS 409
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  316 bits (802), Expect = 1e-84
 Identities = 99/387 (25%), Positives = 172/387 (43%), Gaps = 62/387 (16%)

Query: 12  INILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWM--------KQQYQRVILILV 63
           +  ++ L IF  GF    +  LS  S S+++  P     +          +  R++  ++
Sbjct: 20  LLQIIGLSIFVFGFF-PVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQVI 78

Query: 64  DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKAL 123
           D L  +F++  D        E   +  M   + L+ +G+       A PPT T+ RLKA+
Sbjct: 79  DGLPAEFVLGKD----GKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAM 134

Query: 124 TTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTAAYD 183
            +G +  F+D   NF+  A++ +D+ + Q  ++G  + +LGD+TWL LFP  F +     
Sbjct: 135 VSGAIGGFLDVAFNFNTQALL-DDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGVS 193

Query: 184 SFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGH 243
           SF + D   VD  ++R +                   DE+ + + +++I H+LG+DH GH
Sbjct: 194 SFFVKDTVQVDRNVSRHLP------------------DELNSDDWNLLILHYLGLDHVGH 235

Query: 244 KFGPSHPVMADTLRKMDRIIGQTIET--------------MKSDDHGMTSTGDHGGESEN 289
             G + P+M   L++MD I+                    +   DHGMT  G+HGG S  
Sbjct: 236 TGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYE 295

Query: 290 EIRAGILVHSKKHQI----ILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQL----- 340
           E  + +L       I            Q+D+ PT++LL G+PIP +N+G ++        
Sbjct: 296 ETDSLMLFIGLNSNISDYASATNNVAFQVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLR 355

Query: 341 -------FTRDLWEIARQMMGFVWQDS 360
                     + W++ R M+  +   S
Sbjct: 356 DFEQLRALELNSWQLLRLMLAQIQSSS 382
>dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located at nucleotides
           17-19, followed by a second ATG codon 52 codons
           downstream. And the second ATG codon is potential
           initiation point for translation of NPPase. [Homo
           sapiens]
          Length = 930

 Score =  287 bits (728), Expect = 6e-76
 Identities = 48/306 (15%), Positives = 102/306 (32%), Gaps = 55/306 (17%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C    +   + C    + Q          +L  +D  R ++L               +
Sbjct: 187 SVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHT-------------W 233

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL K G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 234 GGLLPVISKLKKCGT-YTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 291

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSL-FPNQFSKTAAYDSFDIN------DLNTVDDKIARK 200
           SF  ++ +        G+  W++  +    S T  +   D+       D+  + +     
Sbjct: 292 SFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNG---S 348

Query: 201 IFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMD 260
           + F +    ++   + P       +        +    D  GH +GP    +   L+++D
Sbjct: 349 VPFEERILAVLQWLQLP------KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVD 402

Query: 261 RIIGQTIETMKSDD-H---GMTSTGDHGGES------------ENEIRAGILVHSKKHQI 304
            ++G  ++ +K  + H    +    DHG E               +++   +++    ++
Sbjct: 403 GMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARL 462

Query: 305 ILPERP 310
              + P
Sbjct: 463 RPSDVP 468
>pir||A39216 plasma cell membrane glycoprotein PC-1 - human
 gb|AAF36094.1| (AF110304) PDNP1 [Homo sapiens]
 emb|CAC39442.1| (AJ242020) plasma cell membrane glycoprotein [Homo sapiens]
          Length = 925

 Score =  287 bits (727), Expect = 7e-76
 Identities = 48/306 (15%), Positives = 102/306 (32%), Gaps = 55/306 (17%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C    +   + C    + Q          +L  +D  R ++L               +
Sbjct: 182 SVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHT-------------W 228

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL K G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 229 GGLLPVISKLKKCGT-YTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 286

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSL-FPNQFSKTAAYDSFDIN------DLNTVDDKIARK 200
           SF  ++ +        G+  W++  +    S T  +   D+       D+  + +     
Sbjct: 287 SFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNG---S 343

Query: 201 IFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMD 260
           + F +    ++   + P       +        +    D  GH +GP    +   L+++D
Sbjct: 344 VPFEERILAVLQWLQLP------KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVD 397

Query: 261 RIIGQTIETMKSDD-H---GMTSTGDHGGES------------ENEIRAGILVHSKKHQI 304
            ++G  ++ +K  + H    +    DHG E               +++   +++    ++
Sbjct: 398 GMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARL 457

Query: 305 ILPERP 310
              + P
Sbjct: 458 RPSDVP 463
>ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phosphodiesterase 3;
           phosphodiesterase I/nucleotide pyrophosphatase 3;
           phosphodiesterase-I beta; gp130RB13-6; bovine intestinal
           phosphodiesterase [Homo sapiens]
 gb|AAC51813.1| (AF005632) phosphodiesterase I/nucleotide pyrophosphatase beta
           [Homo sapiens]
          Length = 875

 Score =  286 bits (725), Expect = 1e-75
 Identities = 51/269 (18%), Positives = 90/269 (32%), Gaps = 37/269 (13%)

Query: 35  KSSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWY 86
           KS C    +   + C   QQ Q         VIL  +D  R ++L             + 
Sbjct: 130 KSVCQGETSWLEENCDTAQQSQCPEGFDLPPVILFSMDGFRAEYL-------------YT 176

Query: 87  YRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISE 146
           +   M NI KL   G  S   + A  PT T      + TG  P      DN   D  +++
Sbjct: 177 WDTLMPNINKLKTCGIHSKY-MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNK 235

Query: 147 DSFVYQAAQLGKNVTLLGDDTWLS-LFPNQFSKTAAYDSFDIN---DLNTVDDKIARKIF 202
            +F   + +        G   WL+ ++    + T  +   ++       ++       + 
Sbjct: 236 -NFSLSSKEQNNPAWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVP 294

Query: 203 FGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRI 262
           F +  + ++   + P                +F   D  GH  GP    +   L+ +D  
Sbjct: 295 FEERISTLLKWLDLP------KAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHA 348

Query: 263 IGQTIETMKSDD----HGMTSTGDHGGES 287
            G  +E +K  +      +    DHG + 
Sbjct: 349 FGMLMEGLKQRNLHNCVNIILLADHGMDQ 377
>gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattus norvegicus]
          Length = 906

 Score =  286 bits (725), Expect = 1e-75
 Identities = 51/307 (16%), Positives = 98/307 (31%), Gaps = 57/307 (18%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C +  +   + C      Q          +L  +D  R ++L               +
Sbjct: 164 SVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHT-------------W 210

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL   G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 211 GGLLPVISKLKNCGT-YTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 268

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKT--AAYDSFDIN------DLNTVDDKIAR 199
           SF  ++ +    +   G   W++   +Q  ++    +   D+       D+  V +    
Sbjct: 269 SFSLKSKEKFNPLWYKGQPIWVTA-NHQEVRSGTYFWPGSDVEIDGILPDIYKVYNG--- 324

Query: 200 KIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKM 259
            + F +    ++   + P                +    D  GH  GP    +   L+K+
Sbjct: 325 SVPFEERILAVLEWLQLPS------YERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKV 378

Query: 260 DRIIGQTIETMKSDD----HGMTSTGDHGGES------------ENEIRAGILVHSKKHQ 303
           D I+G  ++ +K         +    DHG E               ++    +V+    +
Sbjct: 379 DHIVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAAR 438

Query: 304 IILPERP 310
           +  PE P
Sbjct: 439 LNPPEVP 445
>ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phosphodiesterase 1;
           phosphodiesterase I/nucleotide pyrophosphatase 1
           (homologous to mouse Ly-41 antigen); plasma-cell
           membrane glycoprotein [Homo sapiens]
 sp|P22413|PC1_HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (PLASMA-CELL
           MEMBRANE GLYCOPROTEIN PC-1) [INCLUDES: ALKALINE
           PHOSPHODIESTERASE I ; NUCLEOTIDE PYROPHOSPHATASE
           (NPPASE)]
 gb|AAA63237.1| (M57736) plasma cell membrane glycoprotein PC-1 [Homo sapiens]
 dbj|BAA02054.1| (D12485) NPPase [Homo sapiens]
          Length = 873

 Score =  285 bits (723), Expect = 2e-75
 Identities = 48/306 (15%), Positives = 102/306 (32%), Gaps = 55/306 (17%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C    +   + C    + Q          +L  +D  R ++L               +
Sbjct: 130 SVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHT-------------W 176

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL K G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 177 GGLLPVISKLKKCGT-YTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 234

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSL-FPNQFSKTAAYDSFDIN------DLNTVDDKIARK 200
           SF  ++ +        G+  W++  +    S T  +   D+       D+  + +     
Sbjct: 235 SFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNG---S 291

Query: 201 IFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMD 260
           + F +    ++   + P       +        +    D  GH +GP    +   L+++D
Sbjct: 292 VPFEERILAVLQWLQLP------KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVD 345

Query: 261 RIIGQTIETMKSDD-H---GMTSTGDHGGES------------ENEIRAGILVHSKKHQI 304
            ++G  ++ +K  + H    +    DHG E               +++   +++    ++
Sbjct: 346 GMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARL 405

Query: 305 ILPERP 310
              + P
Sbjct: 406 RPSDVP 411
>ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Rattus norvegicus]
 gb|AAK69654.1|AF340186_1 (AF340186) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  285 bits (722), Expect = 3e-75
 Identities = 50/307 (16%), Positives = 97/307 (31%), Gaps = 57/307 (18%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C +  +   + C      Q          +L  +D  R ++L               +
Sbjct: 164 SVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHT-------------W 210

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL   G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 211 GGLLPVISKLKNCGT-YTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 268

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKT--AAYDSFDIN------DLNTVDDKIAR 199
           SF  ++ +    +   G   W++   +Q  ++    +   D+       D+  V +    
Sbjct: 269 SFSLKSKEKFNPLWYKGQPIWVTA-NHQEVRSGTYFWPGSDVEIDGILPDIYKVYNG--- 324

Query: 200 KIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKM 259
            + F +    ++   + P                +    D  GH  GP    +   L+K+
Sbjct: 325 SVPFEERILAVLEWLQLPS------YERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKV 378

Query: 260 DRIIGQTIETMKSDD----HGMTSTGDHGGES------------ENEIRAGILVHSKKHQ 303
           D I+G  ++ +K         +    DHG E               ++    +V+    +
Sbjct: 379 DHIVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAAR 438

Query: 304 IILPERP 310
           +   E P
Sbjct: 439 LRPTEVP 445
>gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  284 bits (721), Expect = 3e-75
 Identities = 50/307 (16%), Positives = 97/307 (31%), Gaps = 57/307 (18%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C +  +   + C      Q          +L  +D  R ++L               +
Sbjct: 164 SVCQEKKSWVEEACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHT-------------W 210

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL   G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 211 GGLLPVISKLKNCGT-YTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 268

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKT--AAYDSFDIN------DLNTVDDKIAR 199
           SF  ++ +    +   G   W++   +Q  ++    +   D+       D+  V +    
Sbjct: 269 SFSLKSKEKFNPLWYKGQPIWVTA-NHQEVRSGTYFWPGSDVEIDGILPDIYKVYNG--- 324

Query: 200 KIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKM 259
            + F +    ++   + P                +    D  GH  GP    +   L+K+
Sbjct: 325 SVPFEERILAVLEWLQLPS------YERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKV 378

Query: 260 DRIIGQTIETMKSDD----HGMTSTGDHGGES------------ENEIRAGILVHSKKHQ 303
           D I+G  ++ +K         +    DHG E               ++    +V+    +
Sbjct: 379 DHIVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAAR 438

Query: 304 IILPERP 310
           +   E P
Sbjct: 439 LRPTEVP 445
>emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucleotide
           pyrophosphatase 1 (homologous to mouse Ly-41 antigen)
           (PC1, NPPS)) [Homo sapiens]
          Length = 845

 Score =  284 bits (721), Expect = 4e-75
 Identities = 48/306 (15%), Positives = 102/306 (32%), Gaps = 55/306 (17%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C    +   + C    + Q          +L  +D  R ++L               +
Sbjct: 102 SVCQGEKSWVEEPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHT-------------W 148

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL K G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 149 GGLLPVISKLKKCGT-YTKNMRPVYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 206

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSL-FPNQFSKTAAYDSFDIN------DLNTVDDKIARK 200
           SF  ++ +        G+  W++  +    S T  +   D+       D+  + +     
Sbjct: 207 SFSLKSKEKFNPEWYKGEPIWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNG---S 263

Query: 201 IFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMD 260
           + F +    ++   + P       +        +    D  GH +GP    +   L+++D
Sbjct: 264 VPFEERILAVLQWLQLP------KDERPHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVD 317

Query: 261 RIIGQTIETMKSDD-H---GMTSTGDHGGES------------ENEIRAGILVHSKKHQI 304
            ++G  ++ +K  + H    +    DHG E               +++   +++    ++
Sbjct: 318 GMVGMLMDGLKELNLHRCLNLILISDHGMEQGSCKKYIYLNKYLGDVKNIKVIYGPAARL 377

Query: 305 ILPERP 310
              + P
Sbjct: 378 RPSDVP 383
>gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphatase/phosphodiesterase 1
           allotype b [Mus musculus]
          Length = 906

 Score =  283 bits (717), Expect = 1e-74
 Identities = 51/307 (16%), Positives = 100/307 (31%), Gaps = 57/307 (18%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C D  +   +TC      +          +L  +D  R ++L               +
Sbjct: 164 SVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHT-------------W 210

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL   G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 211 GGLLPVISKLKNCGT-YTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 268

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKT--AAYDSFDIN------DLNTVDDKIAR 199
           SF  ++ +    +   G   W++   +Q  K+    +   D+       D+  V +    
Sbjct: 269 SFSLKSKEKFNPLWYKGQPIWVTA-NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNG--- 324

Query: 200 KIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKM 259
            + F +    ++   + P       +        +    D  GH  GP    +   L+K+
Sbjct: 325 SVPFEERILAVLEWLQLPS------HERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKV 378

Query: 260 DRIIGQTIETMKSDD----HGMTSTGDHGGES------------ENEIRAGILVHSKKHQ 303
           DR++G  ++ +K         +    DHG E               ++    +V+    +
Sbjct: 379 DRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAAR 438

Query: 304 IILPERP 310
           +   + P
Sbjct: 439 LRPTDVP 445
>pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse
          Length = 905

 Score =  283 bits (717), Expect = 1e-74
 Identities = 51/307 (16%), Positives = 100/307 (31%), Gaps = 57/307 (18%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C D  +   +TC      +          +L  +D  R ++L               +
Sbjct: 164 SVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHT-------------W 210

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL   G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 211 GGLLPVISKLKNCGT-YTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 268

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKT--AAYDSFDIN------DLNTVDDKIAR 199
           SF  ++ +    +   G   W++   +Q  K+    +   D+       D+  V +    
Sbjct: 269 SFSLKSKEKFNPLWYKGQPIWVTA-NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNG--- 324

Query: 200 KIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKM 259
            + F +    ++   + P       +        +    D  GH  GP    +   L+K+
Sbjct: 325 SVPFEERILAVLEWLQLPS------HERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKV 378

Query: 260 DRIIGQTIETMKSDD----HGMTSTGDHGGES------------ENEIRAGILVHSKKHQ 303
           DR++G  ++ +K         +    DHG E               ++    +V+    +
Sbjct: 379 DRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAAR 438

Query: 304 IILPERP 310
           +   + P
Sbjct: 439 LRPTDVP 445
>ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyrophosphatase 1; 1
           ectonucleotide pyrophosphatase/phosphodiesterase 1 [Mus
           musculus]
 gb|AAA39893.2| (J02700) ecto-nucleotide pyrophosphatase/phosphodiesterase-1 [Mus
           musculus domesticus]
          Length = 905

 Score =  283 bits (717), Expect = 1e-74
 Identities = 51/307 (16%), Positives = 100/307 (31%), Gaps = 57/307 (18%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C D  +   +TC      +          +L  +D  R ++L               +
Sbjct: 164 SVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHT-------------W 210

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL   G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 211 GGLLPVISKLKNCGT-YTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 268

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKT--AAYDSFDIN------DLNTVDDKIAR 199
           SF  ++ +    +   G   W++   +Q  K+    +   D+       D+  V +    
Sbjct: 269 SFSLKSKEKFNPLWYKGQPIWVTA-NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNG--- 324

Query: 200 KIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKM 259
            + F +    ++   + P       +        +    D  GH  GP    +   L+K+
Sbjct: 325 SVPFEERILAVLEWLQLPS------HERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKV 378

Query: 260 DRIIGQTIETMKSDD----HGMTSTGDHGGES------------ENEIRAGILVHSKKHQ 303
           DR++G  ++ +K         +    DHG E               ++    +V+    +
Sbjct: 379 DRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAAR 438

Query: 304 IILPERP 310
           +   + P
Sbjct: 439 LRPTDVP 445
>sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Plasma-cell
           membrane glycoprotein PC-1) [Includes: Alkaline
           phosphodiesterase I ; Nucleotide pyrophosphatase
           (NPPASE)]
          Length = 871

 Score =  281 bits (714), Expect = 2e-74
 Identities = 51/307 (16%), Positives = 100/307 (31%), Gaps = 57/307 (18%)

Query: 36  SSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWYY 87
           S C D  +   +TC      +          +L  +D  R ++L               +
Sbjct: 130 SVCQDKKSWVEETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHT-------------W 176

Query: 88  RGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISED 147
            G +  I KL   G      +    PT T     ++ TG  P      DN   D  ++  
Sbjct: 177 GGLLPVISKLKNCGT-YTKNMRPMYPTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMN-A 234

Query: 148 SFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKT--AAYDSFDIN------DLNTVDDKIAR 199
           SF  ++ +    +   G   W++   +Q  K+    +   D+       D+  V +    
Sbjct: 235 SFSLKSKEKFNPLWYKGQPIWVTA-NHQEVKSGTYFWPGSDVEIDGILPDIYKVYNG--- 290

Query: 200 KIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKM 259
            + F +    ++   + P       +        +    D  GH  GP    +   L+K+
Sbjct: 291 SVPFEERILAVLEWLQLPS------HERPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKV 344

Query: 260 DRIIGQTIETMKSDD----HGMTSTGDHGGES------------ENEIRAGILVHSKKHQ 303
           DR++G  ++ +K         +    DHG E               ++    +V+    +
Sbjct: 345 DRLVGMLMDGLKDLGLDKCLNLILISDHGMEQGSCKKYVYLNKYLGDVNNVKVVYGPAAR 404

Query: 304 IILPERP 310
           +   + P
Sbjct: 405 LRPTDVP 411
>dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus]
          Length = 876

 Score =  276 bits (699), Expect = 2e-72
 Identities = 48/269 (17%), Positives = 87/269 (31%), Gaps = 37/269 (13%)

Query: 35  KSSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWY 86
           K+ C        + C   Q+ Q         VIL  +D  R ++L               
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQT------------- 177

Query: 87  YRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISE 146
           +   + NI KL   G  S   + A  PT T      + TG  P      DN   D  +++
Sbjct: 178 WSTLLPNINKLKTCGLHSKY-MRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNK 236

Query: 147 DSFVYQAAQLGKNVTLLGDDTWLS-LFPNQFSKTAAYDSFDIN---DLNTVDDKIARKIF 202
            +F   + +        G   WL+ ++    + +  +   D+        +    +  + 
Sbjct: 237 -NFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVP 295

Query: 203 FGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRI 262
           +      ++   + P           S    +    D  GHK GP    +   L+ +D  
Sbjct: 296 YESRIATLLQWLDLP------KAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDA 349

Query: 263 IGQTIETMKSDD----HGMTSTGDHGGES 287
            G  +E +K  +      +    DHG + 
Sbjct: 350 FGMLMEGLKQRNLHNCVNIIVLADHGMDQ 378
>ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus norvegicus]
 gb|AAB61535.1| (U78787) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  275 bits (698), Expect = 2e-72
 Identities = 48/269 (17%), Positives = 87/269 (31%), Gaps = 37/269 (13%)

Query: 35  KSSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWY 86
           K+ C        + C   Q+ Q         VIL  +D  R ++L               
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQT------------- 177

Query: 87  YRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISE 146
           +   + NI KL   G  S   + A  PT T      + TG  P      DN   D  +++
Sbjct: 178 WSTLLPNINKLKTCGLHSKY-MRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNK 236

Query: 147 DSFVYQAAQLGKNVTLLGDDTWLS-LFPNQFSKTAAYDSFDIN---DLNTVDDKIARKIF 202
            +F   + +        G   WL+ ++    + +  +   D+        +    +  + 
Sbjct: 237 -NFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVP 295

Query: 203 FGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRI 262
           +      ++   + P           S    +    D  GHK GP    +   L+ +D  
Sbjct: 296 YESRIATLLQWLDLP------KAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDA 349

Query: 263 IGQTIETMKSDD----HGMTSTGDHGGES 287
            G  +E +K  +      +    DHG + 
Sbjct: 350 FGMLMEGLKQRNLHNCVNIIVLADHGMDQ 378
>gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  275 bits (697), Expect = 2e-72
 Identities = 48/269 (17%), Positives = 87/269 (31%), Gaps = 37/269 (13%)

Query: 35  KSSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWY 86
           K+ C        + C   Q+ Q         VIL  +D  R ++L               
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQT------------- 177

Query: 87  YRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISE 146
           +   + NI KL   G  S   + A  PT T      + TG  P      DN   D  +++
Sbjct: 178 WSTLLPNINKLKTCGLHSKY-MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNK 236

Query: 147 DSFVYQAAQLGKNVTLLGDDTWLS-LFPNQFSKTAAYDSFDIN---DLNTVDDKIARKIF 202
            +F   + +        G   WL+ ++    + +  +   D+        +    +  + 
Sbjct: 237 -NFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWPGSDVAVNGSFPNIYRNYSNSVP 295

Query: 203 FGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRI 262
           +      ++   + P           S    +    D  GHK GP    +   L+ +D  
Sbjct: 296 YESRIATLLQWLDLP------KAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDA 349

Query: 263 IGQTIETMKSDD----HGMTSTGDHGGES 287
            G  +E +K  +      +    DHG + 
Sbjct: 350 FGMLMEGLKQRNLHNCVNIIVLADHGMDQ 378
>pir||A57080 cell surface antigen RB13-6 - rat
 emb|CAA88029.1| (Z47987) RB13-6 antigen [Rattus norvegicus]
          Length = 875

 Score =  272 bits (689), Expect = 2e-71
 Identities = 48/269 (17%), Positives = 87/269 (31%), Gaps = 37/269 (13%)

Query: 35  KSSCSDAHAQPGQTCWMKQQYQ--------RVILILVDALRYDFLIPIDENTKKSKEEWY 86
           K+ C        + C   Q+ Q         VIL  +D  R ++L               
Sbjct: 131 KAVCQGEVPWVTEACASSQEPQCPEGFDQPPVILFSMDGFRAEYLQT------------- 177

Query: 87  YRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISE 146
           +   + NI KL   G  S   + A  PT T      + TG  P      DN   D  +++
Sbjct: 178 WSTLLPNINKLKTCGLHSKY-MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNK 236

Query: 147 DSFVYQAAQLGKNVTLLGDDTWLS-LFPNQFSKTAAYDSFDIN---DLNTVDDKIARKIF 202
            +F   + +        G   WL+ ++    + +  +   D+        +    +  + 
Sbjct: 237 -NFSLSSVEKSNPAWWSGQPIWLTAMYQGLKAASYYWLGSDVAVNGSFPNIYRNYSNSVP 295

Query: 203 FGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRI 262
           +      ++   + P           S    +    D  GHK GP    +   L+ +D  
Sbjct: 296 YESRIATLLQWLDLP------KAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDA 349

Query: 263 IGQTIETMKSDD----HGMTSTGDHGGES 287
            G  +E +K  +      +    DHG + 
Sbjct: 350 FGMLMEGLKQRNLHNCVNIIVLADHGMDQ 378
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  267 bits (678), Expect = 4e-70
 Identities = 46/302 (15%), Positives = 112/302 (36%), Gaps = 48/302 (15%)

Query: 1   MGSIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVIL 60
           M     ++   ++++  L IF    +     + + +   D+     +  W  ++  + ++
Sbjct: 1   MAKTKNVISFKLSLIFLLNIFIVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVV 60

Query: 61  ILV--DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQ 118
           +++  D  R+                + ++    NI+ L+  G  +   L+   PT T  
Sbjct: 61  LMISCDGFRF---------------GYQFKTDTPNIDLLISGGTEAKHGLIPVFPTMTFP 105

Query: 119 RLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQ---LGKNVTLLGDDTWLS----L 171
              ++ TG  P +     N   D  ++ + F         LG+ + +   +  L      
Sbjct: 106 NHYSIATGLYPAYHGIIMNKFTDP-VTGEVFNKGLQPKWWLGEPLWVTAVNQGLKAVTYF 164

Query: 172 FPNQFSKTAAYDSFDINDLNTVDDKIARK----IFFGKYYNKMVFCFEGPILQDEMLNSN 227
           +P      +++         T  +         +   +  + ++  F      D + +  
Sbjct: 165 WPGSEVLKSSW---------TCPEGYCPHFNLSVPLEERVDSVLSHF------DHLEDEV 209

Query: 228 SSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS----DDHGMTSTGDH 283
             +++ +F   D  GH +GP  P +   + ++D++IG+ I+ +K     D+  +   GDH
Sbjct: 210 PDLLMLYFDEPDQSGHNYGPDDPRVTTAVSRVDKMIGRVIKGLKQREIFDEVHVILLGDH 269

Query: 284 GG 285
           G 
Sbjct: 270 GM 271
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  266 bits (674), Expect = 1e-69
 Identities = 101/328 (30%), Positives = 149/328 (44%), Gaps = 62/328 (18%)

Query: 3   SIIRILLVSINIL----LALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRV 58
            +    L ++  L    +A+ IF  GFLL R E+   S+CSD    P   C    +    
Sbjct: 4   YLKNKKLTALGFLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSP---CLASPR---- 56

Query: 59  ILILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQ 118
                           + ++    + W  +  +          +  I    ADPPTT+LQ
Sbjct: 57  ---------------SNHDSSSEPKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQ 101

Query: 119 RLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSK 178
           RLK LTTG LPTFID G++F   A++ ED+F+ Q    GK + ++GDDTW  LFPNQF K
Sbjct: 102 RLKGLTTGGLPTFIDIGNSFGAPAIV-EDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQK 160

Query: 179 TAAYDSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGV 238
           +  + SF++ DL+TVD+                       L   +   +  ++IAHFLGV
Sbjct: 161 SYPFPSFNVKDLDTVDNGCIEH------------------LFPTLFKDDWDVLIAHFLGV 202

Query: 239 DHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD----------------DHGMTSTGD 282
           DH GH FG     M + L + + ++ + I  ++S                 DHG T  GD
Sbjct: 203 DHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQTLNGD 262

Query: 283 HGGESENEIRAGILVHS-KKHQIILPER 309
           HGG +  E+   +   S KKH  ++P  
Sbjct: 263 HGGGTAEEVETTMFAMSTKKHTTLVPPE 290
 Score =  171 bits (430), Expect = 5e-41
 Identities = 41/129 (31%), Positives = 58/129 (44%), Gaps = 11/129 (8%)

Query: 754 IALLIPLGFYHLGHSPVISSIPWNAAFVGIPGGTALRVLPALFVLFHLNFSAISSIF--- 810
            +LL    F+  GH      + + AAFVG      +R    L  +    FS I S+F   
Sbjct: 745 WSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIR-QAILLTIETFGFSIILSVFGLP 803

Query: 811 -VISSESESSQ----KMSAPNTAWTLTETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPK 865
            +I   S++ Q    K       + L    V+     T T L  +I RRHLMVW +FAPK
Sbjct: 804 LLIPFHSQTPQAHGEKRHQLFQMYML--FGVISATTVTATILCVTIQRRHLMVWGLFAPK 861

Query: 866 FIFECILTI 874
           F+F+ +  I
Sbjct: 862 FVFDVVDLI 870
 Score = 38.1 bits (88), Expect = 0.62
 Identities = 16/116 (13%), Positives = 36/116 (30%), Gaps = 19/116 (16%)

Query: 429 ITNEVMSLEWIIYRTGCGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSIISMCHKALQ 488
           +  E ++                  +   +   S  T   + L ++    ++        
Sbjct: 436 LLKEQIAEYLNF------------FSSVVELARSKWTEFNLNLMITGFGILVISLILQFL 483

Query: 489 ---IRISI---KSMLSAKVIGPILVI-IHSISLFSNSYVVYEAQVVRYFLQSLVTL 537
                       S LS      + ++ I + S  SNSY++ E +V  + L +   +
Sbjct: 484 AVFHGDKSYAVGSWLSTGAAFTLFIVTIRACSFLSNSYILEEGKVANFLLATTGLI 539
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  262 bits (663), Expect = 2e-68
 Identities = 59/433 (13%), Positives = 127/433 (28%), Gaps = 87/433 (20%)

Query: 129 PTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLF----PNQFSKTAAY-- 182
                    +  +  +  DS   ++    K     G    L +F          T +Y  
Sbjct: 1   EDVSAVAKGWKENP-VEFDSLFNES----KYTWSWGSPDILPMFAKGASGDHVYTYSYDA 55

Query: 183 --DSFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDH 240
             + F   D   +D        F    +          L  ++ N    +   H LG+D 
Sbjct: 56  KREDFGAQDATKLD-----TWVFDNVKDFFHHARNNQSLFSKI-NEEKIVFFLHLLGIDT 109

Query: 241 CGHKFGPSHPVMADTLRKMDRIIGQTIE-------------TMKSDDHGMTSTGDHGGES 287
            GH   PS       ++K+D  + + +               + + DHGMT  G HG   
Sbjct: 110 NGHAHRPSSRDYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGH 169

Query: 288 ENEIRAGILVHSKKHQIIL--------------------PERPIHQIDIVPTISLLMGLP 327
            +E    ++      +                           ++Q DI P ++ L+G+P
Sbjct: 170 PSETLTPLVTWGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVP 229

Query: 328 IPFSNLGTVITQLFTRDLWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDSN- 386
            P +++G +            A  M    + ++V I  +         E+    +     
Sbjct: 230 FPLNSVGILPVDYLNNTDLFKAESM----FTNAVQILEQFKVKMTQKKEVTLPFLFTPFK 285

Query: 387 --TMEEQLDTMSRIQTLLRVSWTQFDDAYINAGIFSLVEAIMFLITNEVMSLEWIIYRTG 444
             +  +Q + + + ++ ++    +FD               +  +  E++ L        
Sbjct: 286 LLSDSKQFNILRKARSYIKHR--KFD--------------EVVSLCKELIHLALKGLSYY 329

Query: 445 CGLLQAALLTDKTDSDGSARTLLLMTLAVSCLSSIISMCHKALQIRISIKS--MLSAKVI 502
               +  L  +             +        S++ +   +  I+   K     S  + 
Sbjct: 330 HTYDRFFLGVNVVIG--------FVGWISYA--SLLIIKSHSNLIKGVSKEVKKPSHLLP 379

Query: 503 GPILVIIHSISLF 515
              + I   ++ F
Sbjct: 380 CSFVAIGILVAFF 392
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  261 bits (662), Expect = 3e-68
 Identities = 62/344 (18%), Positives = 115/344 (33%), Gaps = 74/344 (21%)

Query: 3   SIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQR----- 57
            ++ I L+S      +      FL      LS +S +   ++  +     +   +     
Sbjct: 41  KVLLISLLSTTFTAVIAAVSFAFLF-----LSATSAAAGESKTIKITTTARSLTKLTHPI 95

Query: 58  VILILVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTL 117
           VILI  D  R+                + ++    NI +L+ +G  +   L+   PT T 
Sbjct: 96  VILISSDGFRF---------------GYQFKAPTPNIHRLINNGTSAELGLIPVFPTLTF 140

Query: 118 QRLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQ----LGKNVTLLGDDTWLS--- 170
               ++ TG  P      +N+  D  I+ D F   + +    LG+ +             
Sbjct: 141 PNHYSIVTGLYPPHHGIINNYFVDP-ITGDKFSMASHEPKWWLGEPLWETVAKHGKKAAT 199

Query: 171 -LFPNQFSKTAAYDSFDINDLNTVDDKIARK----IFFGKYYNKMVFCFEGPILQDEMLN 225
             +P        +D                     I F +  + ++  F+ PI      N
Sbjct: 200 YFWPGSEVIKPDWD---------CPSNYCIHYNGSIPFEERVDTVISYFDLPI------N 244

Query: 226 SNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS----DDHGMTSTG 281
                +  +F   DH GH+ GP  P +   +  +D++IG+ I+ ++     +D  +   G
Sbjct: 245 EIPVFMTLYFEDPDHQGHQVGPDDPEITQAVINIDKMIGRLIKGLEKRGVFEDVNIFMVG 304

Query: 282 DHGG----------ESENEIR-------AGILVHSKKHQIILPE 308
           DHG             + EI          +L  S   +    E
Sbjct: 305 DHGMVGTCDKKLIFLDDLEIPSNWVQSYTPLLAISPPPEFSPAE 348
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  257 bits (650), Expect = 7e-67
 Identities = 45/296 (15%), Positives = 108/296 (36%), Gaps = 48/296 (16%)

Query: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILV--D 64
           + L +      L  F    +     + + +   D+     +  W  ++  + +++++  D
Sbjct: 2   LFLSNFLSSSFLIFFIVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVVLMISCD 61

Query: 65  ALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALT 124
             R+                + ++    NI+ L+  G  +   L+   PT T     ++ 
Sbjct: 62  GFRF---------------GYQFKTDTPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIA 106

Query: 125 TGTLPTFIDAGDNFSPDAVISEDSFVYQAAQ---LGKNVTLLGDDTWLS----LFPNQFS 177
           TG  P +     N   D  ++ + F         LG+ + +   +  L      +P+   
Sbjct: 107 TGLYPAYHGIIMNKFTDP-VTGEVFNKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPSSEV 165

Query: 178 KTAAYDSFDINDLNTVDDKIARK----IFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIA 233
             +++         T  +         +   +  + ++  F      D + +    +++ 
Sbjct: 166 LKSSW---------TCPEGYCPHFNLSVPLEERVDSVLSHF------DHLEDEVPDLLML 210

Query: 234 HFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS----DDHGMTSTGDHGG 285
           +F   D  GH +GP  P +   + ++D++IG+ I+ +K     D+  +   GDHG 
Sbjct: 211 YFDEPDQSGHNYGPDDPRVTTAVSRVDKMIGRVIKGLKQREIFDEVHVILLGDHGM 266
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  257 bits (650), Expect = 8e-67
 Identities = 50/302 (16%), Positives = 109/302 (35%), Gaps = 63/302 (20%)

Query: 2   GSIIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILI 61
           G I+  L +++ I+L++ +  NG              SD+ +   +     ++  + +++
Sbjct: 13  GYILYKLSLTVLIVLSVAVTANG--------------SDSPSSYVRRPQPPKKLNKPVVL 58

Query: 62  LV--DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQR 119
           L+  D  R+                + ++ +  NI+ L+  G  +   L+   PT T   
Sbjct: 59  LISCDGFRF---------------GYQFKTETPNIDLLISRGTEAKTGLIPVFPTMTFPN 103

Query: 120 LKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQ---LGKNVTLLGDDTWLS----LF 172
             ++ TG  P       N   D  +S + F         LG+ + +   +  L      +
Sbjct: 104 HYSIATGLYPASHGIIMNKFTDP-VSGELFNRNLNPKWWLGEPLWVTAVNQGLMAATYFW 162

Query: 173 PNQFSKTAAYDSFDINDLNTVDDKIAR-----KIFFGKYYNKMVFCFEGPILQDEMLNSN 227
           P       ++                +      +   +  + ++  F+ P          
Sbjct: 163 PGADVHKGSW---------NCPKGFCKAPYNVSVPLEERVDTILNYFDLP------EREI 207

Query: 228 SSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS----DDHGMTSTGDH 283
              +  +F   D  GH++GP  P + + + K+D++IG+ I  ++      D  +   GDH
Sbjct: 208 PDFMALYFDEPDIQGHEYGPDDPRVTEAVSKVDKMIGRIIMGLEKRKVFSDVHVILLGDH 267

Query: 284 GG 285
           G 
Sbjct: 268 GM 269
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  250 bits (634), Expect = 6e-65
 Identities = 56/300 (18%), Positives = 113/300 (37%), Gaps = 55/300 (18%)

Query: 7   ILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQR-----VILI 61
           +LLV+   L A   F   F   ++ +L   S +     P     + +  ++     V+LI
Sbjct: 56  LLLVTCIALSAASAFAFLFFSSQKPVL---SLNQISKSPAFDRSVARPLKKLDKPVVLLI 112

Query: 62  LVDALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLK 121
             D  R+                + ++ ++ +I +L+ +G  +   L+   PT T     
Sbjct: 113 SSDGFRF---------------GYQFKTKLPSIHRLIANGTEAETGLIPVFPTLTFPNHY 157

Query: 122 ALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQ----LGKNVTLLGDDTWLS----LFP 173
           ++ TG  P +    +N   D   + + F   + +    LG+ +     +  L      +P
Sbjct: 158 SIVTGLYPAYHGIINNHFVDPE-TGNVFTMASHEPEWWLGEPLWETVVNQGLKAATYFWP 216

Query: 174 NQFSKTAAYDSFDINDLNTVDDKIAR----KIFFGKYYNKMVFCFEGPILQDEMLNSNSS 229
                  ++              + +     + F    + ++  F+ P       N   S
Sbjct: 217 GSEVHKGSW---------NCPQGLCQNYNGSVPFDDRVDTILSYFDLPS------NEIPS 261

Query: 230 IIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS----DDHGMTSTGDHGG 285
            +  +F   DH GH+ GP  P + + +  +DR+IG+ I+ ++     +D  M   GDHG 
Sbjct: 262 FMTLYFEDPDHQGHQVGPDDPQITEAVVNIDRLIGRLIDGLEKRGIFEDVTMIMVGDHGM 321
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  242 bits (613), Expect = 2e-62
 Identities = 58/290 (20%), Positives = 112/290 (38%), Gaps = 50/290 (17%)

Query: 12  INILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILVDALRYDFL 71
           + +  AL +  + +LL        S+     A       +++    VILI  D  R+   
Sbjct: 49  LLLTAALAVATS-YLLLILPRTPLSAAPAPAAAARAQVKLEKPV--VILISSDGFRF--- 102

Query: 72  IPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTF 131
                        + ++    +I +L+ +G  +   L+   PT T     ++ TG  P+ 
Sbjct: 103 ------------GYQHKAATPHIHRLIGNGTSAATGLVPIFPTLTFPNHYSIATGLYPSS 150

Query: 132 IDAGDNFSPDAVISEDSFVYQAAQ----LGKNVTLLGDDTWLS----LFPNQFSKTAAYD 183
               +N+ PD  IS D F   + +    LG+ + +   D  +      +P    K  ++D
Sbjct: 151 HGIINNYFPDP-ISGDYFTMSSHEPKWWLGEPLWVTAADQGIQAATYFWPGSEVKKGSWD 209

Query: 184 SFDINDLNTVDDKIARK----IFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVD 239
                      DK  R     + F +  + ++  F+ P       +     +  +F   D
Sbjct: 210 ---------CPDKYCRHYNGSVPFEERVDAILGYFDLPS------DEMPQFLTLYFEDPD 254

Query: 240 HCGHKFGPSHPVMADTLRKMDRIIGQTIETMKS----DDHGMTSTGDHGG 285
           H GH+ GP  P + + + ++D +IG+ I  ++     +D  +   GDHG 
Sbjct: 255 HQGHQVGPDDPAITEAVVRIDEMIGRLIAGLEERGVFEDVNVILVGDHGM 304
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  237 bits (601), Expect = 5e-61
 Identities = 79/227 (34%), Positives = 114/227 (49%), Gaps = 41/227 (18%)

Query: 223 MLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DH 275
           M +    ++IAHFLGVDHCGHK GP HP MA  L +MD++I   +E +++D       DH
Sbjct: 1   MDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDH 60

Query: 276 GMTSTGDHGGESENEIRAGILVHSKKHQII--LPERP--IHQIDIVPTISLLMGLPIPFS 331
           GMT+ GDHGG+SE E+ A + ++S         PE P  I Q+ +VPT++LL+GLPIPF 
Sbjct: 61  GMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFG 120

Query: 332 NLGTVITQLFT------RDLWEIARQMMGFVWQDSVGIFAETYAAQK---NFGELH---- 378
           N+G V+ +LF+           +A+     +    V  F  TY+A        ELH    
Sbjct: 121 NIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQN 180

Query: 379 ---------SHTIRDSNTMEEQLDT-MSRIQTLLR-------VSWTQ 408
                       ++     E  L T ++ +Q  LR        SW +
Sbjct: 181 LFSKASADYQWLLQSPKGAEATLPTVIAELQQFLRGARAMCIESWAR 227
 Score =  186 bits (469), Expect = 1e-45
 Identities = 53/165 (32%), Positives = 70/165 (42%), Gaps = 41/165 (24%)

Query: 752 STIALLIPLGFYHLGHSPVISSIPWNAAFVGIPGG-TALRVLPALFV-----LFHLNFSA 805
           S  AL+    FY  GH PV  +I W+AAFVG P G  +   LPAL V       HL F+ 
Sbjct: 258 SAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAV 317

Query: 806 ISSIFVI-SS--ESESSQKMSAP--------------------------------NTAWT 830
              + ++     ES+  +K   P                                     
Sbjct: 318 GCPLLLLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQL 377

Query: 831 LTETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIV 875
             + L ++ I+     L +SI RRHLMVWK+FAPKFIFE +  IV
Sbjct: 378 GLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIV 422
>gb|AAD05192.1| (AC005587) phosphodiesterase I beta [Homo sapiens]
          Length = 687

 Score =  232 bits (587), Expect = 2e-59
 Identities = 33/196 (16%), Positives = 65/196 (32%), Gaps = 16/196 (8%)

Query: 100 SGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKN 159
            G  S   + A  PT T      + TG  P      DN   D  +++ +F   + +    
Sbjct: 2   CGIHSKY-MRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNK-NFSLSSKEQNNP 59

Query: 160 VTLLGDDTWLS-LFPNQFSKTAAYDSFDIN---DLNTVDDKIARKIFFGKYYNKMVFCFE 215
               G   WL+ ++    + T  +   ++       ++       + F +  + ++   +
Sbjct: 60  AWWHGQPMWLTAMYQGLKAATYFWPGSEVAINGSFPSIYMPYNGSVPFEERISTLLKWLD 119

Query: 216 GPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSDD- 274
            P                +F   D  GH  GP    +   L+ +D   G  +E +K  + 
Sbjct: 120 LP------KAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNL 173

Query: 275 ---HGMTSTGDHGGES 287
                +    DHG + 
Sbjct: 174 HNCVNIILLADHGMDQ 189
>ref|NP_116023.1| (NM_032634) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH01030.1|AAH01030 (BC001030) Similar to phosphatidylinositol glycan, class O [Homo
           sapiens]
          Length = 454

 Score =  229 bits (580), Expect = 1e-58
 Identities = 76/227 (33%), Positives = 110/227 (47%), Gaps = 41/227 (18%)

Query: 223 MLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------DH 275
           M +    +   H LGVDHCGHK GP HP MA  L +MD++I   +E +++D       DH
Sbjct: 1   MDSGEWEVSNQHVLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLENDTLLVVAGDH 60

Query: 276 GMTSTGDHGGESENEIRAGILVHSKKHQII--LPERP--IHQIDIVPTISLLMGLPIPFS 331
           GMT+ GDHGG+SE E+ A + ++S         PE P  I Q+ +VPT++LL+GLPIPF 
Sbjct: 61  GMTTNGDHGGDSELEVSAALFLYSPTAVFPSTPPEEPEVIPQVSLVPTLALLLGLPIPFG 120

Query: 332 NLGTVITQLFT------RDLWEIARQMMGFVWQDSVGIFAETYAAQK---NFGELH---- 378
           N+G V+ +LF+           +A+     +    V  F  TY+A        ELH    
Sbjct: 121 NIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQAKELHQLQN 180

Query: 379 ---------SHTIRDSNTMEEQLDT-MSRIQTLLR-------VSWTQ 408
                       ++     E  L T ++ +Q  LR        SW +
Sbjct: 181 LFSKASADYQWLLQSPKGAEATLPTVIAELQQFLRGARAMCIESWAR 227
 Score =  187 bits (471), Expect = 8e-46
 Identities = 53/165 (32%), Positives = 70/165 (42%), Gaps = 41/165 (24%)

Query: 752 STIALLIPLGFYHLGHSPVISSIPWNAAFVGIPGG-TALRVLPALFV-----LFHLNFSA 805
           S  AL+    FY  GH PV  +I W+AAFVG P G  +   LPAL V       HL F+ 
Sbjct: 258 SAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLFAV 317

Query: 806 ISSIFVI-SS--ESESSQKMSAP--------------------------------NTAWT 830
              + ++     ES+  +K   P                                     
Sbjct: 318 GCPLLLLWPFLCESQGLRKRQQPPGNEADARVRPEEEEEPLMEMRLRDAPQHFYAALLQL 377

Query: 831 LTETLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIV 875
             + L ++ I+     L +SI RRHLMVWK+FAPKFIFE +  IV
Sbjct: 378 GLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIV 422
>pir||T33724 hypothetical protein - Zymomonas mobilis
 gb|AAC70363.1| (AF086791) unknown [Zymomonas mobilis]
          Length = 429

 Score =  229 bits (579), Expect = 2e-58
 Identities = 55/277 (19%), Positives = 90/277 (31%), Gaps = 55/277 (19%)

Query: 32  ILSKSSCSDAHAQPGQTC--WMKQQYQRVILILVDALRYDFLIPIDENTKKSKEEWYYRG 89
           +L  +  S  H+           Q    +ILI +D  R D               +  RG
Sbjct: 22  LLGCAGLSVVHSDAIAATAHVTAQSKTPLILISIDGFRAD---------------YIKRG 66

Query: 90  QMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKALTTGTLPTFIDAGDNFSPDAVISEDS- 148
              N+  L ++G      +    P+ T      L TG  P       N   DA I+ DS 
Sbjct: 67  LTPNLVSLAENG-SYAKVMHPSFPSITFPNHYTLVTGLYPDHHGIVGNNMDDAHITPDSH 125

Query: 149 FVYQAAQL---------GKNVTLLGDDTWL----SLFPNQFSKTAAYDSFDINDLNTVDD 195
           F     Q          G+ + +  +   +      +P   +             ++   
Sbjct: 126 FKMSDHQAATDRRWWDEGEPLWVTAEKQGVVSATMFWPGSEADIEGVRPEMWRQFDS--- 182

Query: 196 KIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGHKFGPSHPVMADT 255
                + F +  +++      P             I  +F  VDH GH +GP    + D 
Sbjct: 183 ----HVPFSERVDQVFSWLAYP------KKKRPQFITLYFENVDHAGHLYGPDSQEVNDN 232

Query: 256 LRKMDRIIGQTIETMKS----------DDHGMTSTGD 282
           L K+D+ IGQ ++ +K            DHGM +T  
Sbjct: 233 LVKIDQTIGQLVQGLKQRGIKANLVIVSDHGMAATSS 269
CPU time:   210.79 user secs.	    3.21 sys. secs	  214.00 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.317    0.164    0.457 

Gapped
Lambda     K      H
   0.270   0.0575    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 540002509
Number of Sequences: 887402
Number of extensions: 26773107
Number of successful extensions: 115951
Number of sequences better than 10.0: 442
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 320
Number of HSP's that attempted gapping in prelim test: 114860
Number of HSP's gapped (non-prelim): 785
length of query: 905
length of database: 277,845,442
effective HSP length: 58
effective length of query: 847
effective length of database: 226,376,126
effective search space: 191740578722
effective search space used: 191740578722
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.9 bits)
S2: 78 (34.5 bits)