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GPI Anchor Biosynthesis Report: T40715 (PIG-N family, Schizosaccharomyces pombe)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (935 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 5

Distribution of 52 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 1082 0.0
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 1072 0.0
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 1069 0.0
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 937 0.0
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 930 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 903 0.0
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 898 0.0
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 862 0.0
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 824 0.0
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 798 0.0
gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melano... 679 0.0
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 618 e-175
ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster] 616 e-175
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 530 e-149
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 512 e-143
gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melano... 462 e-128
ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]... 439 e-122
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 415 e-114
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 414 e-114
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 342 2e-92
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 328 3e-88
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 323 8e-87
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 304 4e-81
ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis ele... 301 3e-80
gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melan... 295 3e-78
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 292 2e-77
dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus] 279 2e-73
ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus ... 279 2e-73
gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norve... 277 4e-73
pir||A57080 cell surface antigen RB13-6 - rat >gi|806379|emb|CAA... 274 7e-72
ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phos... 273 1e-71
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 270 9e-71
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 267 9e-70
pir||T33724 hypothetical protein - Zymomonas mobilis >gi|3089614... 251 5e-65
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 245 3e-63
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 243 1e-62
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 242 2e-62
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 241 4e-62
gb|AAD05192.1| (AC005587) phosphodiesterase I beta [Homo sapiens] 235 4e-60
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 233 1e-59
ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyro... 233 1e-59
dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharom... 233 2e-59
gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase... 229 2e-58
ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyro... 228 2e-58
dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens] 227 6e-58
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 227 6e-58
ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phos... 227 6e-58
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 210 7e-53
Alignments
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score = 1082 bits (2769), Expect = 0.0
 Identities = 325/938 (34%), Positives = 504/938 (53%), Gaps = 44/938 (4%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY-SAGEAPAKRLFLIVGDGLRPDKLLQPH 63
              LG+L H VF  SIFDIYF +PL+HGM    +    PAKRL L V DGLR D L +  
Sbjct: 4   FFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE-- 61

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123
               + E+    APF+R++I + G++GVSHTRVPTESRPGHVALIAGFYEDVSAV KGWK
Sbjct: 62  ----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWK 117

Query: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS-NGIVLDE 182
           +NPV FDS+FN+S++T+S+GS DILPMF++GAS    V T+ Y ++ EDF + +   LD 
Sbjct: 118 ENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
           WVFD++ +    +  ++ L+  ++ +K+VFFLHLLG+DT GH   P S EY +NI+ +D 
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDD 236

Query: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
            ++E+V    ++Y +DG ++++FT+DHGM+D+GSHG G+   T TP + WGAGI+ P + 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 303 KNYGHDE-YSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRK 361
               +D+ +   W L   KR D+ QADIA LM+ L+G+ FP+NSVG +P+ YL+ +   K
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 362 AEVALMNALEIGEQYNLKSASKDQTSI--FFRPYSPLRNYTEVQASFYNSVIADIESGEY 419
           AE    NA++I EQ+ +K   K + ++   F P+  L +    Q        + I+  ++
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSD--SQQLDILRKARSYIKQEKF 414

Query: 420 EIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNI---EPSS 476
           +  +  C       L GL Y   YD L L   V  G++ W+ Y    +   +    + + 
Sbjct: 415 DEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTR 474

Query: 477 KIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFK 536
           K  K    +   +F    +L+  F  IQ+ P  YY Y L P      +       +   +
Sbjct: 475 KEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVE 534

Query: 537 NFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYA 596
           + LT  +          +   L     ++ +V S+F+R   +  L+  A WP+L      
Sbjct: 535 SLLTFPRS-------HFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLT--QLW 585

Query: 597 FSHKTISVSWSVLTSLLCFFTILP-VNKKESLLFIFAGGFAMSVAGVFY--ILYRRNQAF 653
              K   +SW+  + LL  F ++P V +K +L  +   GF + +  +     L +RN   
Sbjct: 586 TRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKL 645

Query: 654 QYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHH 713
                +     +L  ++ M  V  T     SL +   +P + ++V++    +S + P   
Sbjct: 646 VKGELLVLLLQMLSTVLSMYVVYST---HHSLLKKEGLPLMNQIVSWATLASSLVAPLLS 702

Query: 714 IRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKY----- 768
             +       RLA + L+   T  +LS  +EALF +VL   + +W+++E E  +      
Sbjct: 703 STALSQ----RLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSC 758

Query: 769 ---TEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRF 825
                 +             L    IR + F   F+  AFFGTGN+AS+++F L SV  F
Sbjct: 759 KQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCF 818

Query: 826 IPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYL 885
           + VF+P   GAL+M+ IL+PF+ +  AF  +        +  F + + ++DI+ ++FF+L
Sbjct: 819 LTVFSPFMMGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFFL 878

Query: 886 VKDEGSWKDIGVSISHFCISNFLILFITALEHASAILC 923
           VKD GSW DIG SISH+ I   + +F+  L   + +L 
Sbjct: 879 VKDSGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 916
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score = 1072 bits (2743), Expect = 0.0
 Identities = 935/935 (100%), Positives = 935/935 (100%)

Query: 1   MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAPAKRLFLIVGDGLRPDKLL 60
           MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAPAKRLFLIVGDGLRPDKLL
Sbjct: 1   MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAPAKRLFLIVGDGLRPDKLL 60

Query: 61  QPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTK 120
           QPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTK
Sbjct: 61  QPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTK 120

Query: 121 GWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVL 180
           GWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVL
Sbjct: 121 GWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVL 180

Query: 181 DEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYI 240
           DEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYI
Sbjct: 181 DEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYI 240

Query: 241 DGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPT 300
           DGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPT
Sbjct: 241 DGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPT 300

Query: 301 HEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRR 360
           HEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRR
Sbjct: 301 HEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRR 360

Query: 361 KAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYE 420
           KAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYE
Sbjct: 361 KAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYE 420

Query: 421 IAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVK 480
           IAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVK
Sbjct: 421 IAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVK 480

Query: 481 PVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLT 540
           PVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLT
Sbjct: 481 PVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLT 540

Query: 541 VAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHK 600
           VAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHK
Sbjct: 541 VAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHK 600

Query: 601 TISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVT 660
           TISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVT
Sbjct: 601 TISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVT 660

Query: 661 NKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHY 720
           NKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHY
Sbjct: 661 NKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHY 720

Query: 721 FLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKK 780
           FLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKK
Sbjct: 721 FLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKK 780

Query: 781 DAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMY 840
           DAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMY
Sbjct: 781 DAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMY 840

Query: 841 TILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSIS 900
           TILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSIS
Sbjct: 841 TILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSIS 900

Query: 901 HFCISNFLILFITALEHASAILCKNITYTIHEKVN 935
           HFCISNFLILFITALEHASAILCKNITYTIHEKVN
Sbjct: 901 HFCISNFLILFITALEHASAILCKNITYTIHEKVN 935
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score = 1069 bits (2737), Expect = 0.0
 Identities = 335/938 (35%), Positives = 507/938 (53%), Gaps = 44/938 (4%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY-SAGEAPAKRLFLIVGDGLRPDKLLQPH 63
              LG+L H VF  SIFDIYF +PL+HGM    +    PA+RL L V DGLR D L +  
Sbjct: 4   FFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPARRLVLFVADGLRADALYE-- 61

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123
               + E     APF+R+II + G++G+SHTRVPTESRPGHVALIAGFYEDVSAV KGWK
Sbjct: 62  ----LDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWK 117

Query: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFS-SNGIVLDE 182
           +NPV FDS+FN+S++T+S+GS DILPMF++GAS    V T+ Y ++ EDF   +   LD 
Sbjct: 118 ENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAKREDFGAQDATKLDT 176

Query: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
           WVFD + +    +  ++ L+  ++ +KIVFFLHLLGIDT GH   P S +Y  NI+ +D 
Sbjct: 177 WVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDD 236

Query: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
            ++E+V   N++Y NDG ++++FT+DHGM+D+GSHG G+   T TP++ WGAGI+ P   
Sbjct: 237 GVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRV 296

Query: 303 KNYGHDE-YSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRK 361
                D+ +   W L   KR+D+ QADIA LM+ L+G+ FP+NSVG +P+DYL+ +   K
Sbjct: 297 SAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFK 356

Query: 362 AEVALMNALEIGEQYNLKSASKDQTSI--FFRPYSPLRNYTEVQASFYNSVIADIESGEY 419
           AE    NA++I EQ+ +K   K + ++   F P+  L +    Q +      + I+  ++
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSD--SKQFNILRKARSYIKHRKF 414

Query: 420 EIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNI---EPSS 476
           +  +  C       L GL Y   YD   L   V  G++ WI Y    +   +    +  S
Sbjct: 415 DEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVS 474

Query: 477 KIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFK 536
           K VK  S +   +F    +L+  F  IQ+ P  YY Y L P      +   F   +    
Sbjct: 475 KEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVV 534

Query: 537 NFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYA 596
           + LT         L   +   L     ++ +V S+F+R   +  L   AAWP+L      
Sbjct: 535 SVLTYP-------LSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLT--RLW 585

Query: 597 FSHKTISVSWSVLTSLLCFFTILP-VNKKESLLFIFAGGFAMSVAGVFY--ILYRRNQAF 653
              K  S+SW+  + LL  F ++P V +K  +  +   G  + +  +     L +R  +F
Sbjct: 586 TRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSF 645

Query: 654 QYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHH 713
                + +   VL  ++ M  V  T     SL R   +P + +++++    +S ++P   
Sbjct: 646 IKEELLVHLLQVLSTVLSMYVVYST---QSSLLRKQGLPLMNQIISWATLASSLVVP--- 699

Query: 714 IRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYT---- 769
                     RL  + L+   T  +LS  +EALF +VL   + +W+ +E E  + +    
Sbjct: 700 -LLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQQSGVCC 758

Query: 770 ----EQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRF 825
                 +   Y+        L L  IR + F   F+  AFFGTGN+AS+++F L SV  F
Sbjct: 759 KQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCF 818

Query: 826 IPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYL 885
           + VF+P   GAL+M+ IL+PF+ +  AF  +        +  F + + ++DI+ ++FF+L
Sbjct: 819 LTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFL 878

Query: 886 VKDEGSWKDIGVSISHFCISNFLILFITALEHASAILC 923
           VKD GSW DIG SISH+ I   + +F+  L   + +L 
Sbjct: 879 VKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 916
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  937 bits (2398), Expect = 0.0
 Identities = 275/829 (33%), Positives = 434/829 (52%), Gaps = 37/829 (4%)

Query: 113 EDVSAVTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELED 172
           EDVSAV KGWK+NPV FDS+FN+S++T+S+GS DILPMF++GAS    V T+ Y ++ ED
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAKRED 59

Query: 173 FS-SNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSV 231
           F   +   LD WVFD + +    +  ++ L+  ++ +KIVFFLHLLGIDT GH   P S 
Sbjct: 60  FGAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSR 119

Query: 232 EYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIA 291
           +Y  NI+ +D  ++E+V   N++Y NDG ++++FT+DHGM+D+GSHG G+   T TP++ 
Sbjct: 120 DYKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVT 179

Query: 292 WGAGIQSPTHEKNYGHDE-YSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIP 350
           WGAGI+ P        D+ +   W L   KR+D+ QADIA LM+ L+G+ FP+NSVG +P
Sbjct: 180 WGAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILP 239

Query: 351 LDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSI--FFRPYSPLRNYTEVQASFYN 408
           +DYL+ +   KAE    NA++I EQ+ +K   K + ++   F P+  L +    Q +   
Sbjct: 240 VDYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSD--SKQFNILR 297

Query: 409 SVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVF 468
              + I+  +++  +  C       L GL Y   YD   L   V  G++ WI Y    + 
Sbjct: 298 KARSYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLII 357

Query: 469 SLNI---EPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIH 525
             +    +  SK VK  S +   +F    +L+  F  IQ+ P  YY Y L P      + 
Sbjct: 358 KSHSNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVL 417

Query: 526 SIFPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLA 585
             F   +    + LT         L   +   L     ++ +V S+F+R   +  L   A
Sbjct: 418 REFQVIQDLVVSVLTYP-------LSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFA 470

Query: 586 AWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILP-VNKKESLLFIFAGGFAMSVAGVFY 644
           AWP+L         K  S+SW+  + LL  F ++P V +K  +  +   G  + +  +  
Sbjct: 471 AWPFLT--RLWTRAKMTSLSWTFFSLLLAVFPLMPVVGRKPDISLVMGAGLLVLLLSLCV 528

Query: 645 --ILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGL 702
              L +R  +F     + +   VL  ++ M  V  T     SL R   +P + +++++  
Sbjct: 529 VTSLMKRKDSFIKEELLVHLLQVLSTVLSMYVVYST---QSSLLRKQGLPLMNQIISWAT 585

Query: 703 FITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELE 762
             +S ++P             RL  + L+   T  +LS  +EALF +VL   + +W+ +E
Sbjct: 586 LASSLVVP----LLSSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIE 641

Query: 763 TELQKYT--------EQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASL 814
            E  + +          +   Y+        L L  IR + F   F+  AFFGTGN+AS+
Sbjct: 642 QETLQQSGVCCKQKLTSIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASI 701

Query: 815 STFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGM 874
           ++F L SV  F+ VF+P   GAL+M+ IL+PF+ +  AF  +        +  F + + +
Sbjct: 702 NSFDLASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVI 761

Query: 875 ADIVTINFFYLVKDEGSWKDIGVSISHFCISNFLILFITALEHASAILC 923
           +DI+ ++FF+LVKD GSW DIG SISH+ I   + +F+  L   + +L 
Sbjct: 762 SDIMALHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQLLT 810
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  930 bits (2378), Expect = 0.0
 Identities = 390/932 (41%), Positives = 558/932 (59%), Gaps = 41/932 (4%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQ-YSAGEAPAKRLFLIVGDGLRPDKLLQPH 63
           LL +G+LFH+ +L SIFDIYF++PL+HGM    S    PAKRLFLIVGDGLR D      
Sbjct: 9   LLAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKV 68

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123
           +  V G+ + + APF+RS++ NN T+G+SHTR+PTESRPGHVA+IAGFYEDVSAVTKGWK
Sbjct: 69  THPVSGKTE-FLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWK 127

Query: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEW 183
            NPVNFDS FNQS HTYSFGS DILPMF +GASDP++VDT+MY    EDF+ + I LD +
Sbjct: 128 SNPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSIELDAF 187

Query: 184 VFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGK 243
           VF  LD+L   S  +  L   + +D  VFFLHLLG DT GH+  P S EY +N++YID +
Sbjct: 188 VFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYIDDQ 247

Query: 244 IQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEK 303
           I  L+DK+ N +  D  ++++FTADHGMS FGSHGDG+ +NTRTP++AWGAG+  P H  
Sbjct: 248 IPILIDKV-NKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVHNP 306

Query: 304 NYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAE 363
               D Y+  W L+ IKR D++QADIA+LMSYL+G+N+P NSVG++P+ Y+D     K  
Sbjct: 307 FPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDKLA 366

Query: 364 VALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFY----NSVIADIESGEY 419
               NA  I EQY +K      +  F++ Y     + E   S Y     ++I  I  GE 
Sbjct: 367 ALYNNARSILEQYLVKQDEVIDSQFFYKEYF---KFVEKSHSHYLEEIETLIQRISEGEN 423

Query: 420 E---IAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGY-VICFVFSLNIEPS 475
                AI       Q  L GL YL  Y+W  +R+IV FG++ WI +  I F+ S  +E  
Sbjct: 424 YLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENV 483

Query: 476 SKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGF 535
               K   +   V  +I  LL  I FY Q SP  +Y Y LFP  F   I +     + G 
Sbjct: 484 IDDQKASPLSHAVFGSIGILLNWILFY-QHSPFNFYMYLLFPLYFWSYIFTNRSVLRSGI 542

Query: 536 KNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADY 595
           K F        G S  K + I++ I+ + + IVY +FHR  F++I   LA +P++     
Sbjct: 543 KEFFK------GTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFYPFIC---- 592

Query: 596 AFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQY 655
                ++++ W + + LL  FT+    K E L  I   G    +   FY LY+ +     
Sbjct: 593 GVRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLL-IILSAFYALYKIHS---R 648

Query: 656 SSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITS-YIIPSHHI 714
            ++ T     +Q+ ++ A + VT +   SLQ    +P   ++  + +F  S +++P  H 
Sbjct: 649 INSYTRAIFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHY 708

Query: 715 RSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHP 774
           R   + +  RL I++LTF+P+  +L+ISFE+LFY +    +  W+E+E +++        
Sbjct: 709 RKPNNDYKVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIK-------- 760

Query: 775 EYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQ 834
           E   +KD  +   L  +R+S+  +  + VAFFGTGNVAS+S+F+L+SV R +P+F+P   
Sbjct: 761 EMKTQKDENW---LQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPIFDPFLM 817

Query: 835 GALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKD 894
           GALLM  +++P+  LS   GI+N +L         L + M+DI+++NFFYL++ EGSW D
Sbjct: 818 GALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRTEGSWLD 877

Query: 895 IGVSISHFCISNFLILFITALEHASAILCKNI 926
           IG++IS++C++    LF+  LE    +L KN+
Sbjct: 878 IGITISNYCLAILSSLFMLILEVLGHVLLKNV 909
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  903 bits (2311), Expect = 0.0
 Identities = 274/814 (33%), Positives = 426/814 (51%), Gaps = 44/814 (5%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY-SAGEAPAKRLFLIVGDGLRPDKLLQPH 63
              LG+L H VF  SIFDIYF +PL+HGM    +    PAKRL L V DGLR D L +  
Sbjct: 4   FFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE-- 61

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123
               + E+    APF+R++I + G++GVSHTRVPTESRPGHVALIAGFYEDVSAV KGWK
Sbjct: 62  ----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWK 117

Query: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS-NGIVLDE 182
           +NPV FDS+FN+S++T+S+GS DILPMF++GAS    V T+ Y ++ EDF + +   LD 
Sbjct: 118 ENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
           WVFD++ +    +  ++ L+  ++ +K+VFFLHLLG+DT GH   P S EY +NI+ +D 
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDD 236

Query: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
            ++E+V    ++Y +DG ++++FT+DHGM+D+GSHG G+   T TP + WGAGI+ P + 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 303 KNYGHDE-YSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRK 361
               +D+ +   W L   KR D+ QADIA LM+ L+G+ FP+NSVG +P+ YL+ +   K
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 362 AEVALMNALEIGEQYNLKSASKDQTSI--FFRPYSPLRNYTEVQASFYNSVIADIESGEY 419
           AE    NA++I EQ+ +K   K + ++   F P+  L +    Q        + I+  ++
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSD--SQQLDILRKARSYIKQEKF 414

Query: 420 EIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNI---EPSS 476
           +  +  C       L GL Y   YD L L   V  G++ W+ Y    +   +    + + 
Sbjct: 415 DEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTR 474

Query: 477 KIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFK 536
           K  K    +   +F    +L+  F  IQ+ P  YY Y L P      +       +   +
Sbjct: 475 KEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVE 534

Query: 537 NFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYA 596
           + LT  +          +   L     ++ +V S+F+R   +  L+  A WP+L      
Sbjct: 535 SLLTFPRS-------HFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLT--QLW 585

Query: 597 FSHKTISVSWSVLTSLLCFFTILP-VNKKESLLFIFAGGFAMSVAGVFY--ILYRRNQAF 653
              K   +SW+  + LL  F ++P V +K +L  +   GF + +  +     L +RN   
Sbjct: 586 TRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKL 645

Query: 654 QYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHH 713
                +     +L  ++ M  V  T     SL +   +P + ++V++    +S + P   
Sbjct: 646 VKGELLVLLLQMLSTVLSMYVVYST---HHSLLKKEGLPLMNQIVSWATLASSLVAPLLS 702

Query: 714 IRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKY----- 768
             +       RLA + L+   T  +LS  +EALF +VL   + +W+++E E  +      
Sbjct: 703 STALSQ----RLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSC 758

Query: 769 ---TEQLHPEYSRKKDAKFHLSLSHIRISLFFYI 799
                 +             L    IR + F + 
Sbjct: 759 KQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLFF 792
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  898 bits (2297), Expect = 0.0
 Identities = 277/820 (33%), Positives = 428/820 (51%), Gaps = 44/820 (5%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY-SAGEAPAKRLFLIVGDGLRPDKLLQPH 63
              LG+L H VF  SIFDIYF +PL+HGM    +    PAKRL L V DGLR D L +  
Sbjct: 4   FFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE-- 61

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123
               + E+    APF+R++I + G++GVSHTRVPTESRPGHVALIAGFYEDVSAV KGWK
Sbjct: 62  ----LDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWK 117

Query: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS-NGIVLDE 182
           +NPV FDS+FN+S++T+S+GS DILPMF++GAS    V T+ Y ++ EDF + +   LD 
Sbjct: 118 ENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
           WVFD++ +    +  ++ L+  ++ +K+VFFLHLLGIDT GH   P S EY +NI+ +D 
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDD 236

Query: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
            ++E+V    ++Y +DG ++++FT+DHGM+D+GSHG G+   T TP + WGAGI+ P + 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 303 KNYGHDE-YSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRK 361
               +D+ +   W L   KR D+ QADIA LM+ L+G+ FP+NSVG +P+ YL+ +   K
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 362 AEVALMNALEIGEQYNLKSASKDQTSI--FFRPYSPLRNYTEVQASFYNSVIADIESGEY 419
           AE    NA++I EQ+ +K   K + ++   F P+  L +    Q        + I+  ++
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSD--SQQLDILRKARSYIKQEKF 414

Query: 420 EIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNI---EPSS 476
           +  +  C       L GL Y   YD L L   V  G++ W+ Y    +   +    + + 
Sbjct: 415 DEVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTR 474

Query: 477 KIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFK 536
           K  K    +   +F    +L+  F  IQ+ P  YY Y L P      +       +   +
Sbjct: 475 KEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVE 534

Query: 537 NFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYA 596
           + LT  +          +   L     ++ +V S+F+R   +  L+  A WP+L      
Sbjct: 535 SLLTFPRS-------HFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLT--QLW 585

Query: 597 FSHKTISVSWSVLTSLLCFFTILP-VNKKESLLFIFAGGFAMSVAGVFY--ILYRRNQAF 653
              K   +SW+  + LL  F ++P V +K +L  +   GF + +  +     L +RN   
Sbjct: 586 TRAKITFLSWAFFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKL 645

Query: 654 QYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHH 713
                +     +L  ++ M  V  T     SL +   +P + ++V++    +S + P   
Sbjct: 646 VKGELLVLLLQMLSTVLSMYVVYST---HHSLLKKEGLPLMNQIVSWATLASSLVAPLLS 702

Query: 714 IRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKY----- 768
             +       RLA + L+   T  +LS  +EALF +VL   + +W+++E E  +      
Sbjct: 703 STALSQ----RLASILLSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSC 758

Query: 769 ---TEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAF 805
                 +             L    IR + F  + I   F
Sbjct: 759 KQKLTSIQFTCDTDIAQFRQLCPDDIRRAFFLILLIFPVF 798
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  862 bits (2204), Expect = 0.0
 Identities = 264/938 (28%), Positives = 447/938 (47%), Gaps = 88/938 (9%)

Query: 1   MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY--SAGEAPAKRLFLIVGDGLRPDK 58
           M  + L+  I  H+V + SIFD+Y+ +PL+HG+     ++ EAPAKR+F+I  DGLR D 
Sbjct: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT 60

Query: 59  LLQPHSEKVIGEEQTYAAPFLRSIIQ-NNGTFGVSHTRVPTESRPGHVALIAGFYEDVSA 117
               + +K          P+L SI+    G +G+S + +PTESRPGHVA+ AG  ED+SA
Sbjct: 61  -FNKYPDKS---------PYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISA 110

Query: 118 VTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS-N 176
           V KGWKKNPV FDSVFN+S +++ +GS DI+ +F     D    ++F YS++ EDF+S +
Sbjct: 111 VAKGWKKNPVQFDSVFNRSSYSWMWGSPDIVNLF----DDLPNAESFSYSADEEDFASKD 166

Query: 177 GIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVEN 236
              LD+WVF+  +  L  +  D+ L D +   K +FFLHLLGIDT GH   P S +Y++N
Sbjct: 167 ASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDN 226

Query: 237 IQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGI 296
           I+ +D  I E V  + + +  D  ++W+FT+DHGM+D+GSHG G+ D   TP +AWGAG+
Sbjct: 227 IKVVDSGI-EKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGV 285

Query: 297 QSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDC 356
           +                       ++D+ Q D+A L+S L+G   PVNS+G +P+  ++ 
Sbjct: 286 KQGG-------------------PKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNS 326

Query: 357 S-SRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIE 415
             S  + +    N  ++ EQ      +K +  ++FR +    +  +   S   ++     
Sbjct: 327 KGSSYEFKAIEANFKQLKEQIIFLKNAKSR-RLWFRQFEKFGD--KAMESLRTTLAQLGR 383

Query: 416 SGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPS 475
              + +A       +  +   + +  RYD  +L + V   +++WI  V+ F+ +   + +
Sbjct: 384 DRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIALVVSFLHNSTSKEN 443

Query: 476 SKIVKPVSV-VKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLG 534
             ++ P  + +  +A ++ F   C     Q+    Y    ++    L+    +    +  
Sbjct: 444 LSLLVPHHLFIIPLACSLLFTAYCSLSMTQTI---YIILPIYLISILENHSKLTQRIREH 500

Query: 535 FKNFLTVAKQKHGFSLLKIL------FISLCILCLLQFIVYSYFHREGFSVILMGLAAWP 588
            K         +    +++       F+   I   +   V ++  R   + + + L A P
Sbjct: 501 VKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICI--FVLTFMDRAFLAAVFVLLMALP 558

Query: 589 -WLLHADYAFSHKTISVSWSVLTSLLCFFTILP-VNKKESLLFIFAGGFAMSVAGVFYIL 646
            +  H   ++  KT    W  L  +LC F  LP V     +          +     + L
Sbjct: 559 QFYSHPIVSYWSKT----WLTLCLVLCIFPFLPAVGVSTHIPLCILSPIITAFL--CHRL 612

Query: 647 YRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAI--------------- 691
             R         +    + +Q       + V     + +++ I                 
Sbjct: 613 -SRRSCLTRIQRMLELMIYVQ-SATAFMIAVVNYGFEKVKKLIQNNWKKKKSNSKSSQSL 670

Query: 692 --PPILRLVAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYV 749
             P I R +++     S I PS        Y +DRL    L F     +LSIS+E+LF +
Sbjct: 671 QPPSIARWISWTSIPLSVIAPS---LLTGPYLVDRLIAYALCFYVPYSLLSISYESLFML 727

Query: 750 VLFITLGLWMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTG 809
           +  + L L++  E       E L  +    K +        +R ++    F+    FGTG
Sbjct: 728 IFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGE--YVELRRTVVCVSFVLCPLFGTG 785

Query: 810 NVASLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFG-IMNKRLGGIQQVTF 868
           N AS+++F   ++  FI VF+P T   LL+  +L+P + +++AF  I+      IQ++  
Sbjct: 786 NFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQESIQRLCC 845

Query: 869 FLAVGMADIVTINFFYLVKDEGSWKDIGVSISHFCISN 906
           F  +   D +++ FF+ ++DEGSW DIG+SIS F +S 
Sbjct: 846 FSLI-FTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 882
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  824 bits (2108), Expect = 0.0
 Identities = 196/943 (20%), Positives = 371/943 (38%), Gaps = 78/943 (8%)

Query: 7   LLGILFHVVFLKSIFDIYFVTPLIHGMKQYSA-----GEAPAKRLFLIVGDGLRPDKLLQ 61
           +  ++ H++ L SI  IYF + ++  ++  S       E PA RL + V DGLR   +L 
Sbjct: 4   IQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLA 63

Query: 62  PHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKG 121
            H   V         P LR +       G+S    PT +RPGH+A+  GF ED +A    
Sbjct: 64  DHCSAV---------PDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLT- 113

Query: 122 WKKNPVNFDSVFNQSRHTYSFGSEDILPMFSE--GASDPSRVDTFMYSSELEDFSSNGIV 179
              NP  FDSVFN+SR+   +   ++  +F+       P R +TF  S       S+ + 
Sbjct: 114 --WNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSD-----ISDRLR 166

Query: 180 LDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQY 239
           LD+W FD++   +      + L D      ++FF++L  ID   H   P+S+ + E + Y
Sbjct: 167 LDQWTFDKVRNFMTNEQNVQPLRD---ATSVIFFVYLADIDLAEHVHMPNSLNFREKLNY 223

Query: 240 IDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSP 299
               I++  +   + + ND  ++++ TAD+G+S    HG G      TP I WGAG++  
Sbjct: 224 TQRGIRQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRS 279

Query: 300 THEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSR 359
                     ++   N   +    ++Q  +A LMS L+GL  P+N++  +PL +L+ S +
Sbjct: 280 APNPGQN---FTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQ 336

Query: 360 RKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGE- 418
            + +V  +NA+++  Q  +    + +  I +       +    +   Y  +I  + + E 
Sbjct: 337 YELQVLHLNAMQLLAQARI-LIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQ 395

Query: 419 YEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIE-PSSK 477
           YE A++     ++     + Y   Y  L L       YL W       +  L  E    K
Sbjct: 396 YEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVW---FYLLLVRLARESNHPK 452

Query: 478 IVKPVSVV-KRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFP-NTKLGF 535
             +   +    +   +  L++     +Q  P     Y L P   L L  +  P   +   
Sbjct: 453 SERKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDRDLM 512

Query: 536 KNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADY 595
             F           +L ++ I +  +     ++   FH     ++ + +     L +   
Sbjct: 513 CQF----------PVLHLVGIVMPGV----LLILMAFHNSHIGLLYLPIVC---LNNRRA 555

Query: 596 AFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQY 655
            F      + W  L  LL    IL V +  SL FI      + +     + +    +   
Sbjct: 556 FFRPSLKLIFWLALVFLLS--GILLVKQSASLHFITDT-IGVYIGNSHVVYFSMILSIIR 612

Query: 656 SSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIR 715
              + ++      ++ MA + VT         +  +   +    +   + +++   +   
Sbjct: 613 PLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYLLFAFLSIPYSGT 672

Query: 716 SCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPE 775
                   RL ++         ML+ S  +LF  ++     L +EL  E   Y       
Sbjct: 673 K---DLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAI 729

Query: 776 YSRKKDAKF-------------HLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSV 822
            +++++ +                     R +    +++ ++FFGTG+     TF   + 
Sbjct: 730 ANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTFKPMTS 789

Query: 823 KRFIPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINF 882
           + F P F+     A ++  I +P I + ++   +        +  F     M D +++ F
Sbjct: 790 RLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYF 849

Query: 883 FYLVKDEGSWKDIGVSISHFCISNFLILFITALEHASAILCKN 925
            Y V + GS + +  S+    +S+  I+ +      +     N
Sbjct: 850 CYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLAN 892
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  798 bits (2041), Expect = 0.0
 Identities = 253/943 (26%), Positives = 424/943 (44%), Gaps = 113/943 (11%)

Query: 6   LLL-GILFHVVFLKSIFDIYFVTPLIHGMKQYS-----AGEAPAKRLFLIVGDGLRPDKL 59
            +   ++ HV+ L SIF IYF +P+I G+           E PA RL LIV DG R D  
Sbjct: 2   WIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSF 61

Query: 60  LQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVT 119
                     EE     P LR I    G  GVS TRVPTE+RPGH+ LIAG YED SAV 
Sbjct: 62  F---------EENCRYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVL 112

Query: 120 KGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELE-DFSSNGI 178
           +GWK NP++FD+VFN+S  TY++G+ D+L +FS   S+   ++   Y+ +L+     +  
Sbjct: 113 RGWKSNPIDFDTVFNRSSQTYAWGANDVLNVFSH-VSNGGEINLRFYNHDLDFSPGYDAY 171

Query: 179 VLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQ 238
             DEWVF R+  LL Q  E      +     +VFFLHLLG+DT GH   P + ++   ++
Sbjct: 172 EEDEWVFKRVKLLLQQKRE-----ALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLE 226

Query: 239 YIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQS 298
             +  +  +  +    +  D  ++++ TADHGM+D G+         RT  +    G   
Sbjct: 227 KTEKGVYAIYQEFERVF-PDKRTAYLLTADHGMTDSGASRAVPKPGGRT-FMPNNEGPAM 284

Query: 299 PTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSS 358
           P HE                     ++QA +  LMS L+GL  P+N+ G++PL YL+ S 
Sbjct: 285 PLHE---------------------LEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSK 323

Query: 359 RRKAEVALMNALEIGEQYNLKSASKDQTSIFF----RPYSPLRNYTEVQASFYNSVIADI 414
             +A  A +NAL++ EQY   +  K     FF      Y  L    E    + ++++   
Sbjct: 324 EYEAMAAHVNALQLLEQY--VALQKQHKKGFFADILLEYDVLN--AEAIKRYKDTIVQLQ 379

Query: 415 ESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFV------- 467
           +  EY + I+         L G+ Y   Y   +L       +L W+ Y+   +       
Sbjct: 380 KKREYSLCIDKSQVIMSQALEGIDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASK 439

Query: 468 FSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSI 527
             L +E S+KIV+       +  ++  L+IC+    Q +P     Y L P  +   + ++
Sbjct: 440 VELVLERSNKIVR-----VSIVSSVIVLIICLLS--QGTPLDISFYLLLP--YFVWLKAL 490

Query: 528 FPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILC-LLQFIVYSYFHREGFSVILMGLAA 586
            P       NF +     +    L+     L +L    + +V+++F R   ++     A 
Sbjct: 491 QPWN----INFSSSPASAYSVPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFAC 546

Query: 587 WPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYIL 646
           +      ++ +  +    SW  L  +L  F +LP++      ++   G  +     F+  
Sbjct: 547 YN--SWENFQWKSRD-FFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIVIFTNSFWNS 603

Query: 647 YRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITS 706
             R   ++  +  +N  ++LQ          T+  A      I IP  L+L ++   + +
Sbjct: 604 KSR-LCYRNHTKYSNALILLQ----------TILCAYLHSNGINIPIPLKLASWLYLVYA 652

Query: 707 YIIPSHHIRSCKHYFLD-RLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETEL 765
           +      I   K   LD RLA +          L  S+EA+F  +L I L + +      
Sbjct: 653 FA----SILLSKESRLDLRLAQIGFNLGSLYATLCTSYEAVFVQLLTIELNISLR----- 703

Query: 766 QKYTEQLHPEYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRF 825
                         + A+   S+  +  +L  Y F   + FG+GN+AS+S+F  +  + +
Sbjct: 704 -------------AQSARAERSVLRLAFTLLLYTFF--SLFGSGNIASISSFDPNIARCY 748

Query: 826 IPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYL 885
           +  F P     L++  +LVP + + +     ++ +   ++  F   + + D++ +NF +L
Sbjct: 749 LSHFAPFVIMGLVLLKLLVPVVLIMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFL 808

Query: 886 VKDEGSWKDIGVSISHFCISNFLILFITALEHASAILCKNITY 928
           V+++GSW DIG SISHF I     L +  + + +  L + I +
Sbjct: 809 VRNQGSWLDIGTSISHFVIMEVTTLVMLVIFYTAKQLLRVIPW 851
>gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melanogaster]
 gb|AAL28155.1| (AY060607) GH02677p [Drosophila melanogaster]
          Length = 858

 Score =  679 bits (1735), Expect = 0.0
 Identities = 132/750 (17%), Positives = 271/750 (35%), Gaps = 66/750 (8%)

Query: 185 FDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKI 244
           F  L +L  +  +   L  + + +K+V  ++L  +        P  + +   +      I
Sbjct: 136 FSHLSDLRRRLTKRACLEKLWYANKLVMLVNLAEVGGAS----PLDIGFQMKLHNTQRNI 191

Query: 245 QELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKN 304
           ++  + +   + ND  +++++T+ HG++ FGSHG G+ +    P + WGAG++  T    
Sbjct: 192 RDAYELIEATF-NDSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENIT 250

Query: 305 YGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEV 364
               ++ L  N   ++   + Q  +A LMS L+GL  PVN++  +P  Y+  S     + 
Sbjct: 251 S---DFVLN-NGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKS 306

Query: 365 ALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQ--ASFYNSVIADIESGEYEIA 422
             +NAL++  Q   K+  +      F  + P     ++Q  A + N +   ++ G    A
Sbjct: 307 VHLNALQLLTQA--KAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKA 364

Query: 423 IEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVKPV 482
           +E      +  L  L++   Y  + L        L W  Y    +  L     S+ V   
Sbjct: 365 LETSTLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQ---LVKL-----SQNVMAP 416

Query: 483 SVVKR-------VAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGF 535
             ++R       +      LL+    ++Q +P       + P     +  +  P      
Sbjct: 417 HYMRRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGGWI 476

Query: 536 KNFLTVAKQKHGFSLLKI-LFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHAD 594
              L   +   G + + I      C L L   +   +++R G              LH  
Sbjct: 477 FEPLKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRG-------------WLHPS 523

Query: 595 YAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQ 654
                K ++    VL      ++     K   +L        +    +  ++ R      
Sbjct: 524 ----PKFLAWLALVLLLGGFLWS----QKGMQILMTTNYRVVLQAISMLVVIVRP--CVL 573

Query: 655 YSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHI 714
             +           +I    + V        +    +P  L    +   I ++       
Sbjct: 574 NEN-----HKWKVWVINGGILFVAAIGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSS 628

Query: 715 RSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHP 774
           R+       RL ++         +LS S+ +LF   L I   + +E+  + ++  E +  
Sbjct: 629 RTTPQS---RLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKI 685

Query: 775 EYSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQ 834
             S K            R ++   ++   + FGTG+     T+  +S + F+P  +    
Sbjct: 686 LTSSK------HLQMCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLV 739

Query: 835 GALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKD 894
             L++  +L+P I + A+   ++       +  F   + + + V + F   V     W  
Sbjct: 740 PLLVLIHLLIPSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPM 799

Query: 895 IGVSISHFCISNFLILFITALEHASAILCK 924
              S+ H  ++   ++ I A E    I  +
Sbjct: 800 AHPSVVHALLAQLTVILILACESIVTIFFR 829
 Score = 95.7 bits (236), Expect = 3e-18
 Identities = 37/139 (26%), Positives = 59/139 (41%), Gaps = 22/139 (15%)

Query: 2   FGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAG-----EAPAKRLFLIVGDGLRP 56
             +     +L H++ L  I  I++ +  +  ++             A RL + + +GLR 
Sbjct: 3   LWK--SKVVLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRA 60

Query: 57  DKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVS 116
           D L   +            A ++R II   G  G+S T VPT +R   VAL AGF    S
Sbjct: 61  DTLFSDNCSG---------AVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPS 111

Query: 117 AVTKGWKKNPVNFDSVFNQ 135
            +         NFD++FN+
Sbjct: 112 ILPT------SNFDTIFNR 124
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  618 bits (1578), Expect = e-175
 Identities = 254/662 (38%), Positives = 364/662 (54%), Gaps = 42/662 (6%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSA--GEAPAKRLFLIVGDGLRPDKLLQP 62
           L++LG+  H V++ SIFDIYF TP++HGM        E PAKRL L++ DGLR DK  +P
Sbjct: 46  LVVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFSEPPAKRLVLLISDGLRADKFFEP 105

Query: 63  HSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGW 122
                  EE  Y APFLR+II+N G +GVSH R PTESRPGHVA+IAGFYED SAVTKGW
Sbjct: 106 D------EEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGW 159

Query: 123 KKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDE 182
           K NPV FDSVFNQSRHT++FGS DI+P+F       +      Y  E EDF+++   LDE
Sbjct: 160 KANPVEFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWN---SYPHEYEDFATDASFLDE 216

Query: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
           W FD+ + LL +S  D +L ++LH+DK+V FLHLLG D+ GH   P S  Y+ N++ +D 
Sbjct: 217 WSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDK 276

Query: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
            I E V  +   Y  D  +S++FTADHGMSD GSHGDG+  NT TP++AWGAGIQ P   
Sbjct: 277 -IAERVYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPA 335

Query: 303 KNYGHDEY--------------SLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQ 348
               H +                  W L  ++R+D+ QADIA LMS L+GL  PVNSVG 
Sbjct: 336 SGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGN 395

Query: 349 IPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASF-Y 407
           +PL Y+  +   + E  + N  +I  Q   KS  K   S+FF+P+ PL     V  SF  
Sbjct: 396 LPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYIKSSNSLFFKPFKPL-----VHHSFSL 450

Query: 408 NSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFV 467
           + +   I +  YE A++         L GL Y Q YDWL+L +++  GY  W+  +   V
Sbjct: 451 SQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHV 510

Query: 468 FSLNIEPSSKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSI 527
                  S  + K   +   ++  +   ++ +   ++ SPP Y+ Y +  T+FL     I
Sbjct: 511 LQCYSSLSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAY-IGMTVFLWT--QI 567

Query: 528 FPNTKLGFKNFLTVAKQKHGFSLLKILFISLCILCLLQFIVYSYFHREGFS--VILMGLA 585
           F   +   +      +++     +K+LF +   + +++ +V+S+  R+ ++   ++ G+ 
Sbjct: 568 FSEYR-LIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWFFLIAGVV 626

Query: 586 AWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFI--FAGGFAMSVAGVF 643
           A   LLH    +    I V   +    L  FT++P    ++   +  F G     + G  
Sbjct: 627 A-SILLHFSIPWRS-GIPVFVCISCWFLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWC 684

Query: 644 YI 645
            I
Sbjct: 685 VI 686
 Score =  300 bits (762), Expect = 7e-80
 Identities = 85/331 (25%), Positives = 150/331 (44%), Gaps = 44/331 (13%)

Query: 627 LLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQ 686
           +  +FA   A+ +  +         +F      T   L+       A V  ++ +  S+ 
Sbjct: 590 IKLLFAAAVAVVIVELLV------HSFTERKLYTWFFLI-------AGVVASILLHFSIP 636

Query: 687 RNIAIPPILRLVAFGLFITSYI---IPSHHIRSCKHYFLDRLAILFLT------------ 731
               IP  + +  + L + + +   IP ++         +   I                
Sbjct: 637 WRSGIPVFVCISCWFLSVFTLMPAEIPDNNNLVSPFLGANDTDIFGWCVICDGVFVDKAS 696

Query: 732 --------FSPTMCMLSISFEALFYVVLFITLGLWMELET--------ELQKYTEQLHPE 775
                    +    ++S  +EA+FY  L + L  W+  E         +    +E    E
Sbjct: 697 NAESRIAFVTSVHKLVSCRYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEE 756

Query: 776 YSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQG 835
           +      + +L LS +RI L F +  NVAFFGTGN AS+++F + SV RFI +F+P    
Sbjct: 757 HITIGSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMA 816

Query: 836 ALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDI 895
           ALL++ + +PF+ +  AF  + K +   +   +FL +  +DI+TI+FF+LVK+ GSW +I
Sbjct: 817 ALLIFKLFIPFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEI 876

Query: 896 GVSISHFCISNFLILFITALEHASAILCKNI 926
           G SISHF I +  ++F+  L   + +  ++I
Sbjct: 877 GNSISHFGIVSAQVVFVLLLFALTNLYTRSI 907
>ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster]
          Length = 656

 Score =  616 bits (1573), Expect = e-175
 Identities = 117/687 (17%), Positives = 236/687 (34%), Gaps = 70/687 (10%)

Query: 248 VDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGH 307
           + +  + + +      +          GSHG G+ +    P + WGAG++  T       
Sbjct: 1   MTRKRHTFIHQHTVLLI---------SGSHGGGSDEEREAPFLLWGAGVKHVTENITS-- 49

Query: 308 DEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALM 367
            ++ L  N   ++   + Q  +A LMS L+GL  PVN++  +P  Y+  S     +   +
Sbjct: 50  -DFVLN-NGVGMQLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHL 107

Query: 368 NALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQ--ASFYNSVIADIESGEYEIAIEH 425
           NAL++  Q   K+  +      F  + P     ++Q  A + N +   ++ G    A+E 
Sbjct: 108 NALQLLTQA--KAIIRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALET 165

Query: 426 CFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEPSSKIVKPVSVV 485
                +  L  L++   Y  + L        L W  Y    +  L     S+ V     +
Sbjct: 166 STLAIKVALKSLKFYHNYYHIPLVVTTVLALLGWQFYQ---LVKL-----SQNVMAPHYM 217

Query: 486 KR-------VAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNF 538
           +R       +      LL+    ++Q +P       + P     +  +  P         
Sbjct: 218 RRGYLTWCTIFLASLGLLLGEMVFLQWAPFMTVICLVVPFGVWCMTLAALPQNGGWIFEP 277

Query: 539 LTVAKQKHGFSLLKI-LFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAF 597
           L   +   G + + I      C L L   +   +++R G              LH     
Sbjct: 278 LKHLRWIVGPAAVMIASIYCNCPLSLAYILCVGFYNRRG-------------WLHPS--- 321

Query: 598 SHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSS 657
             K ++    VL      ++     K   +L        +    +  ++ R        +
Sbjct: 322 -PKFLAWLALVLLLGGFLWS----QKGMQILMTTNYRVVLQAISMLVVIVRP--CVLNEN 374

Query: 658 TVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSC 717
                      +I    + V        +    +P  L    +   I ++       R+ 
Sbjct: 375 -----HKWKVWVINGGILFVAAIGIFLKEMGKPVPLYLFAANWAYLIYAFASVPCSSRTT 429

Query: 718 KHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYS 777
                 RL ++         +LS S+ +LF   L I   + +E+  + ++  E +    S
Sbjct: 430 PQS---RLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEVHEKFKEADEDVKILTS 486

Query: 778 RKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGAL 837
            K            R ++   ++   + FGTG+     T+  +S + F+P  +      L
Sbjct: 487 SK------HLQMCYRFAVSILLYFYASLFGTGHWVGGFTYLANSARLFLPDSSSGLVPLL 540

Query: 838 LMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGV 897
           ++  +L+P I + A+   ++       +  F   + + + V + F   V     W     
Sbjct: 541 VLIHLLIPSIVIMASVVALSSFGRQQIRTIFSSLMLICNAVVLFFVVFVPHNAYWPMAHP 600

Query: 898 SISHFCISNFLILFITALEHASAILCK 924
           S+ H  ++   ++ I A E    I  +
Sbjct: 601 SVVHALLAQLTVILILACESIVTIFFR 627
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  530 bits (1353), Expect = e-149
 Identities = 189/395 (47%), Positives = 267/395 (66%), Gaps = 12/395 (3%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY-SAGEAPAKRLFLIVGDGLRPDKLLQPH 63
              LG+L H VF  SIFDIYF +PL+HGM    +    PAKRL L V DGLR D L +  
Sbjct: 4   FFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE-- 61

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123
               + E+    APF+R++I + G++GVSHTRVPTESRPGHVALIAGFYEDVSAV KGWK
Sbjct: 62  ----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWK 117

Query: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS-NGIVLDE 182
           +NPV FDS+FN+S++T+S+GS DILPMF++GAS    V T+ Y ++ EDF + +   LD 
Sbjct: 118 ENPVEFDSLFNESKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
           WVFD++ +    +  ++ L+  ++ +K+VFFLHLLGIDT GH   P S EY +NI+ +D 
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDD 236

Query: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
            ++E+V    ++Y +DG ++++FT+DHGM+D+GSHG G+   T TP + WGAGI+ P + 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 303 KNYGHDE-YSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRK 361
               +D+ +   W L   KR D+ QADIA LM+ L+G+ FP+NSVG +P+ YL+ +   K
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 362 AEVALMNALEIGEQYNLKSASKDQTSI--FFRPYS 394
           AE    NA++I EQ+ +K   K + ++   F P+ 
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  512 bits (1305), Expect = e-143
 Identities = 128/883 (14%), Positives = 260/883 (28%), Gaps = 174/883 (19%)

Query: 3   GR------LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAP-------------- 42
            +         + ++ +   LKS  D + +   +                          
Sbjct: 19  WKYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAP 78

Query: 43  --AKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSII-QNNGTFGVSHTRVPTE 99
              +R  +++ D LR D L+  +          +  P+  S++   N          PT 
Sbjct: 79  KIFERAVIVIIDALRYDFLIPYN--DSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTT 136

Query: 100 SRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQ----SRHTYSFGSEDILPMFSEGA 155
           +      L  G       +   +    ++ D++  Q     +     G +    +F +  
Sbjct: 137 TSQRLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYL 196

Query: 156 SDPS--RVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFF 213
           ++       +F               ++++VFD + +                 +  V  
Sbjct: 197 NETLSQPAFSFNVPDLHGV----DNKVNQYVFDYIKD----------------ANFDVLI 236

Query: 214 LHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSD 273
            H LG+D +GH   PD     + +  +D  ++E++D +      D ++  +   DHGM +
Sbjct: 237 AHYLGVDHVGHRLGPDHPTMRDKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDN 290

Query: 274 FGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALM 333
            G+HG  + D   + +  +         ++                K +   Q D+   +
Sbjct: 291 KGNHGGDSFDEINSVLWMYSKKPTFGYLKQPG--------------KVLSANQVDLVPTL 336

Query: 334 SYLVGLNFPVNSVGQIPLD-YLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRP 392
           S L+G   P  ++G +  + +        ++   +N  ++                FF  
Sbjct: 337 SLLLGNPIPYGNLGTLIPEPFYYYGDEYLSKAQKINIGQLNR--------------FFSE 382

Query: 393 YSP-LRNYT--EVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLR 449
           Y     ++    V  +  + +       +Y                   Y +        
Sbjct: 383 YDLDASDFLSSSVHKNNNSYLDQYFLDFDY-------------ARDAFSYFKAIWAEFSL 429

Query: 450 SIVFFGYLSWIGYVICFVFSLNIEPSSKIV-------KPVSVVKRV-AFNIPFLLICIFF 501
             +  G+L     +I   F+L +    K V          SV+K +    I  L      
Sbjct: 430 FPMIIGFL----LLIIGGFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILANNEL- 484

Query: 502 YIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKI-LFISLCI 560
               SP     Y L P  F  L++S        FK F+ +       + L +  F S   
Sbjct: 485 ---HSPFPAEFYVLLP-SFYILLNSFNQKLMEYFKGFVKLDYFSIFITFLHVCSFGSNSF 540

Query: 561 LCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHKTISVSWSVLTSLLCFFTILP 620
                 +     H    ++ L+      +          +   +      S L  F +L 
Sbjct: 541 TVWEDRLC----HFLIITIGLVMF-CKCF---------SEMSPLFACSTYSALA-FILLQ 585

Query: 621 VNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLK 680
           V            G                    Y ST  N    L VL +MA   + L 
Sbjct: 586 VISSYVTNCREEQG------AFCVS--------TYISTPDNSLRTLIVLALMALSSIILP 631

Query: 681 IADSLQRN--IAIPPILRLVAFGLFI---TSYIIPSHHIRSCKHYFLDRLAILFLTFSPT 735
           +   L     + +   L  ++   F    +S    +HH+ +       +   +  + + T
Sbjct: 632 LILQLHLRRVLGLSLKLYHLSILYFFELISSIFWIAHHVFANDALLEKQYHHVLYSLANT 691

Query: 736 MC------------MLSIS-------FE-ALFYVVLFITLGLWMELETELQKYTEQLHPE 775
                         +LS S        E + F   L  +   +++               
Sbjct: 692 YVICILGVLIWQFFLLSRSKFAKINVIERSYFVFALLYSFLSFLQRPLGHLSLFSCFLQI 751

Query: 776 YSRKKDAKFHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFA 818
               +  ++  S+ H   S+   +     FF TGN A++S+  
Sbjct: 752 LLLIQLKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAAISSLD 794
>gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melanogaster]
          Length = 559

 Score =  462 bits (1177), Expect = e-128
 Identities = 98/618 (15%), Positives = 224/618 (35%), Gaps = 83/618 (13%)

Query: 312 LPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALE 371
                  +    +    + ALMS L+G+  PV S G +P   L+ S R +A   L+NA +
Sbjct: 2   ANEAGLRLPLHVLNTPHLTALMSALLGVPPPVYSRGMLPKGMLNASLRYEANAMLINAKQ 61

Query: 372 IGEQY-NLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYEIAIEHCFHFS 430
           +  Q   L+     +   F+  +  + N+ +          A  +   +   +++  ++ 
Sbjct: 62  LLAQARRLRELHPKRMPAFWLSFQMMDNFVKESL-------ALKKQRRFRALLDYSCNYM 114

Query: 431 QTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFV---FSLNIEPSSKIVKPVSVVKR 487
             ++ G+ Y + Y   +  + V F  ++WI  + C +            + V     +  
Sbjct: 115 PVLIKGMDYFKDYYRHVSITAVSFAGIAWIYCLRCHLTVGKKCRNLIEIQEVISSKRLVY 174

Query: 488 VAF---NIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGFKNFLTVAKQ 544
                  +  +L+ I   ++  P       L P+++ +    I               + 
Sbjct: 175 ARGFHRLLTGVLV-IIMMLERIPLVVQAILLIPSLYWRTTLKILGE------------RP 221

Query: 545 KHGFSLLKILFISLCILCLLQFIVYSYFHREGFSVILMGLAAWPWLLHADYAFSHKT-IS 603
           K       +    L ++C        +F R   +V  +G A++    +   AF  +    
Sbjct: 222 KMVCRKSLMSTALLALICFG-----GFFRRYILAVGYLGFASY----NNREAFKRRGHQF 272

Query: 604 VSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQAFQYSSTVTNKQ 663
             W +L   L   + LP    ESL     G     +  +F  + R      Y + +T   
Sbjct: 273 YLWLLLLLGLTVVSALP----ESLGCSQPGA---LMFSIFLTVLRPLACGVYLNLLTWLS 325

Query: 664 LVLQVLIIMATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIPSHHIRSCKHYFLD 723
            +   +++ A   + +            P I+ LV++       +    ++++ + +F D
Sbjct: 326 NI--PVLLAALEYILIGWH---------PWIMYLVSWIYLGFLVLWQRRNLQASEVFFFD 374

Query: 724 RLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKKDAK 783
                    S    +   S+E++   +L + L L + ++    K  E + P+ +      
Sbjct: 375 --------LSTLYTLTCTSYESVVIQMLAMELQLALRMK---LKRNESIGPKTA------ 417

Query: 784 FHLSLSHIRISLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMYTIL 843
                     + +  ++   + F  G+  +   F LD +      ++P+T G +++  ++
Sbjct: 418 ----------AHYILVYSWYSLFIIGSFPAFDDF-LDILHETCFGYSPLTYGLVMVLKLI 466

Query: 844 VPFIALSAAFGIMNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSISHFC 903
           +P++ +        K L   +Q  F   + M   +++   + + + G W+DI    + F 
Sbjct: 467 LPWLLVLCIMAGNYKSLASYEQQIFVRLLLMNSAMSLVLLHGITNVGPWRDILSRFAEFA 526

Query: 904 ISNFLILFITALEHASAI 921
           + +   L    L   + +
Sbjct: 527 VVHVFPLVWLLLWRLTQL 544
>ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]
 pir||T33168 hypothetical protein M01B12.2 - Caenorhabditis elegans
          Length = 559

 Score =  439 bits (1120), Expect = e-122
 Identities = 110/531 (20%), Positives = 210/531 (38%), Gaps = 46/531 (8%)

Query: 403 QASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGY 462
             S   ++        + +A       +  +   + +  RYD  +L + V   +++WI  
Sbjct: 1   MESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWIAL 60

Query: 463 VICFVFSLNIEPSSKIVKPVSV-VKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFL 521
           V+ F+ +   + +  ++ P  + +  +A ++ F   C     Q+    Y    ++    L
Sbjct: 61  VVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTI---YIILPIYLISIL 117

Query: 522 QLIHSIFPNTKLGFKNFLTVAKQKHGFSLLKIL------FISLCILCLLQFIVYSYFHRE 575
           +    +    +   K         +    +++       F+   I   +   V ++  R 
Sbjct: 118 ENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICI--FVLTFMDRA 175

Query: 576 GFSVILMGLAAWP-WLLHADYAFSHKTISVSWSVLTSLLCFFTILP-VNKKESLLFIFAG 633
             + + + L A P +  H   ++  KT    W  L  +LC F  LP V     +      
Sbjct: 176 FLAAVFVLLMALPQFYSHPIVSYWSKT----WLTLCLVLCIFPFLPAVGVSTHIPLCILS 231

Query: 634 GFAMSVAGVFYILYRRNQAFQYSSTVTNKQLVLQVLIIMATVPVTLKIADSLQRNIAI-- 691
               +     + L  R         +    + +Q       + V     + +++ I    
Sbjct: 232 PIITAFL--CHRL-SRRSCLTRIQRMLELMIYVQ-SATAFMIAVVNYGFEKVKKLIQNNW 287

Query: 692 ---------------PPILRLVAFGLFITSYIIPSHHIRSCKHYFLDRLAILFLTFSPTM 736
                          P I R +++     S I PS        Y +DRL    L F    
Sbjct: 288 KKKKSNSKSSQSLQPPSIARWISWTSIPLSVIAPS---LLTGPYLVDRLIAYALCFYVPY 344

Query: 737 CMLSISFEALFYVVLFITLGLWMELETELQKYTEQLHPEYSRKKDAKFHLSLSHIRISLF 796
            +LSIS+E+LF ++  + L L++  E       E L  +    K +        +R ++ 
Sbjct: 345 SLLSISYESLFMLIFLVLLTLFVRFEFGHLSDVELLQLKVDSTKISTGE--YVELRRTVV 402

Query: 797 FYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFG-I 855
              F+    FGTGN AS+++F   ++  FI VF+P T   LL+  +L+P + +++AF  I
Sbjct: 403 CVSFVLCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASI 462

Query: 856 MNKRLGGIQQVTFFLAVGMADIVTINFFYLVKDEGSWKDIGVSISHFCISN 906
           +      IQ++  F  +   D +++ FF+ ++DEGSW DIG+SIS F +S 
Sbjct: 463 VRFDQESIQRLCCFSLI-FTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 512
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  415 bits (1058), Expect = e-114
 Identities = 149/379 (39%), Positives = 225/379 (59%), Gaps = 39/379 (10%)

Query: 1   MFGRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY--SAGEAPAKRLFLIVGDGLRPDK 58
           M  + L+  I  H+V + SIFD+Y+ +PL+HG+     ++ EAPAKR+F+I  DGLR D 
Sbjct: 1   MSWKFLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQEAPAKRIFIISADGLRYDT 60

Query: 59  LLQPHSEKVIGEEQTYAAPFLRSIIQ-NNGTFGVSHTRVPTESRPGHVALIAGFYEDVSA 117
               + +K          P+L SI+    G +G+S + +PTESRPGHVA+ AG  ED+SA
Sbjct: 61  -FNKYPDKS---------PYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISA 110

Query: 118 VTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS-N 176
           V KGWKKNPV FDSVFN+S +++ +GS DI+ +F     D    ++F YS++ EDF+S +
Sbjct: 111 VAKGWKKNPVQFDSVFNRSSYSWMWGSPDIVNLF----DDLPNAESFSYSADEEDFASKD 166

Query: 177 GIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVEN 236
              LD+WVF+  +  L  +  D+ L D +   K +FFLHLLGIDT GH   P S +Y++N
Sbjct: 167 ASNLDKWVFEHFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDN 226

Query: 237 IQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGI 296
           I+ +D  I E V  + + +  D  ++W+FT+DHGM+D+GSHG G+ D   TP +AWGAG+
Sbjct: 227 IKVVDSGI-EKVQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGV 285

Query: 297 QSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDC 356
           +                       ++D+ Q D+A L+S L+G   PVNS+G +P+  ++ 
Sbjct: 286 KQGG-------------------PKLDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNS 326

Query: 357 S-SRRKAEVALMNALEIGE 374
             S  + +    N  ++  
Sbjct: 327 KGSSYEFKAIEANFKQVIN 345
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  414 bits (1055), Expect = e-114
 Identities = 152/307 (49%), Positives = 212/307 (68%), Gaps = 9/307 (2%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQY-SAGEAPAKRLFLIVGDGLRPDKLLQPH 63
              LG+L H VF  SIFDIYF +PL+HGM    +    PAKRL L V DGLR D L +  
Sbjct: 4   FFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE-- 61

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWK 123
               + E+    APF+R++I + G++GVSHTRVPTESRPGHVALIAGFYEDVSAV KGWK
Sbjct: 62  ----LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWK 117

Query: 124 KNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS-NGIVLDE 182
           +NPV  DS+FN+ ++T+S+GS DILPMF++GAS    V T+ Y ++ EDF + +   LD 
Sbjct: 118 ENPVESDSLFNERKYTWSWGSPDILPMFAKGAS-GDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 183 WVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDG 242
           WVFD++ +    +  ++ L+  ++ +K+VFFLHLLGIDT GH   P S EY +NI+ +D 
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDD 236

Query: 243 KIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHE 302
            ++E+V    ++Y +DG ++++FT+DHGM+D+GSHG G+   T TP + WGAGI+ P + 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 303 KNYGHDE 309
               +D+
Sbjct: 297 SAQQYDD 303
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  342 bits (869), Expect = 2e-92
 Identities = 87/423 (20%), Positives = 153/423 (35%), Gaps = 53/423 (12%)

Query: 1   MFGRLLLLGILFHVVFLKS--IFDIYFVTP--LIHGMKQYS-AGEAPAKRLFLIVGDGLR 55
           M  +   L +   V+ L +  +F   F+    L+ G  +   + EAP ++  ++V D  R
Sbjct: 1   MLWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFR 60

Query: 56  PDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFG-VSHTRVPTESRPGHVALIAGFYED 114
            D      S            P L   I + G     +H+  PT + P    L  G   +
Sbjct: 61  SDFAFSDQSN----------CPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPN 110

Query: 115 VSAVTKGWKKNP-----VNFDSVFNQ----SRHTYSFGSEDILPMFSEGASDPSRVDTFM 165
                    ++       N DS   Q     R  + FG +  + +F     D     +F 
Sbjct: 111 FLDAVLNIAESDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFF 170

Query: 166 YSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHN 225
                    S+   +D  V   +D  L Q             +  V  LH LG+D IGH 
Sbjct: 171 V--------SDYTEVDNNVTRHIDTQLDQKT-----------EWDVLILHYLGLDHIGHK 211

Query: 226 KHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNT 285
             P+S       + +D    +L        + D  +  +   DHGM++ G+HG  +   T
Sbjct: 212 TGPESPFMPAKQKEMDDIFDKLY------NSCDDDTVLILLGDHGMNEVGNHGGSSAGET 265

Query: 286 RTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNS 345
              ++   A  +  T +     +   LPW  T      + Q D+   ++ L+GLN P N+
Sbjct: 266 SAAMVF--ASPKFETAQLTETAETSPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNN 323

Query: 346 VGQIPLDYLDC-SSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQA 404
           +G +    L   S   +  V   NA ++ +    +++ +      +  Y  L +   V+ 
Sbjct: 324 LGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKD 383

Query: 405 SFY 407
            + 
Sbjct: 384 YYN 386
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  328 bits (833), Expect = 3e-88
 Identities = 72/468 (15%), Positives = 133/468 (28%), Gaps = 99/468 (21%)

Query: 11  LFHVVFLKSIFDIY-----FVTPLIHGMKQYSA----GEAP------------------- 42
              +      F  Y     F +  +    + +      E P                   
Sbjct: 5   SVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMA 64

Query: 43  --AKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTES 100
               R+ L++ D LR D     HS +            +  I  ++     S    PT +
Sbjct: 65  SRFSRVVLVLIDALRFDFAQPQHSHR------------ILEIQPHHARLYRSQVDPPTTT 112

Query: 101 RPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQ----SRHTYSFGSEDILPMFSEGAS 156
                AL  G           +  + +  D++  Q     R     G +    +F    S
Sbjct: 113 MQRLKALTTGSLPTFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFS 172

Query: 157 DPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHL 216
                 +F               +D  + + L               M   +  V   H 
Sbjct: 173 KAFFFPSFNVRDL--------DTVDNGILEHL------------YPTMDSGEWDVLIAHF 212

Query: 217 LGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGS 276
           LG+D  GH   P   E  + +  +D  IQ LV+++ N       +  V   DHGM+  G 
Sbjct: 213 LGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLEN------DTLLVVAGDHGMTTNGD 266

Query: 277 HGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYL 336
           HG  +       +  +      P               +    +   I Q  +   ++ L
Sbjct: 267 HGGDSELEVSAALFLYSPTAVFP---------------STPPEEPEVIPQVSLVPTLALL 311

Query: 337 VGLNFPVNSVGQIPLDYLD--------CSSRRKAEVALMNALEIGEQYNLKSASKDQTSI 388
           +GL  P  ++G++  +            S+  +A    +NA ++    +  SA+      
Sbjct: 312 LGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQA 371

Query: 389 FFRPYSPLRNYTEVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSG 436
               +     +++  A +             E  +       Q  L G
Sbjct: 372 -KELHQLQNLFSKASADYQWL---LQSPKGAEATLPTVIAELQQFLRG 415
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  323 bits (821), Expect = 8e-87
 Identities = 76/479 (15%), Positives = 141/479 (28%), Gaps = 99/479 (20%)

Query: 10  ILFHVVFLKSIFDIY-----FVTPLIHGMKQYSAG------------------------- 39
           +   +      F  Y     F +  +    + +                           
Sbjct: 12  VSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGACWM 71

Query: 40  EAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSI---------IQNNGTFG 90
            +   R+ L++ D LR D   QP    V GE      PFL  +           ++G   
Sbjct: 72  PSRFSRVVLVLIDALRFDFA-QPQRSHVPGEPPVS-VPFLGKLGSLQRILESQPHHGRLY 129

Query: 91  VSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQ----SRHTYSFGSED 146
            S    PT +     AL  G           +  + +  D+V  Q     R     G + 
Sbjct: 130 RSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGDDT 189

Query: 147 ILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLH 206
              +F    S      +F               +D  + + L               +  
Sbjct: 190 WRDLFPGAFSQAFFFSSFNVRDLH--------TVDNGILEHL------------YPTLDG 229

Query: 207 RDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFT 266
               V   H LG+D  GH   P   E  + +  +D  IQ L++++ N       +  V  
Sbjct: 230 GSWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLEN------DTLLVVA 283

Query: 267 ADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQ 326
            DHGM+  G HG  +       +  +      P               ++   +   I Q
Sbjct: 284 GDHGMTMNGDHGGDSELEVSAALFLYSPTALFP---------------SVPPEEPEVIPQ 328

Query: 327 ADIAALMSYLVGLNFPVNSVGQIPLDYLD---------CSSRRKAEVALMNALEIGEQYN 377
             +   ++ L+GL  P  + G++  +             S+  +     +NA ++    +
Sbjct: 329 VSLVPTLALLLGLPIPFGNTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQVSRFLH 388

Query: 378 LKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSG 436
             SA+          +     +++  A + + +    +  E E A+       Q  L G
Sbjct: 389 TYSAATQDLQ-VKELHRLQTLFSKASARYQHFLR---DPQEAEAALSTLTAEFQQFLRG 443
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  304 bits (772), Expect = 4e-81
 Identities = 81/481 (16%), Positives = 147/481 (29%), Gaps = 87/481 (18%)

Query: 2   FGRLLLLGILFHVVFLKSIFDIYF-----------------VTPLIHGMKQYSAGEAPAK 44
              +  +G+L   +    +F I F                     + GM + +       
Sbjct: 6   SWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGM-ELTPPPPAYD 64

Query: 45  RLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGH 104
              L++ D LR D       +          A     +          H  +PT + P  
Sbjct: 65  SFVLLLVDALRDDF-----PDATSMPVAYSRACEKLKL----------HVDIPTVTMPRL 109

Query: 105 VALIAGFYEDVSAVTKGWKKNPVNFDSVFNQSRH---TYSF-GSEDILPMFSEGA-SDPS 159
            ++  G   +   +           DS  ++ +      SF G    + +F         
Sbjct: 110 KSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVE 169

Query: 160 RVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGI 219
             D+F  +   E         D  V   L+  L +S            D  +  LH LG+
Sbjct: 170 NHDSFYVNDFYEG--------DRNVTKTLETELERS------------DWSLLILHYLGL 209

Query: 220 DTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGD 279
           D IGH +   S      ++ +D  +++++D       +      + T DHGM+D G HG 
Sbjct: 210 DHIGHVEGNASPRVPLKLKEMDEVVKKILDHK-----SFPNVLLMLTGDHGMADGGGHGG 264

Query: 280 GNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGL 339
                T  P+  +          K     +                Q D+A  +S L+ +
Sbjct: 265 NTPAETLVPLYLY-----YNNCSKTPSASK-------------RYNQIDLAPTLSVLLSV 306

Query: 340 NFPVNSVGQIPLDYLDC-SSRRKAEVALMNALEIGEQYNLKSASKD-QTSIFFRPYSPLR 397
             P  S+G +  + L   S   +      NA  +  +  +K   +    S ++  Y    
Sbjct: 307 EIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNAT 366

Query: 398 NYTEVQASFYNSVIADIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYL 457
              +              S  Y    +   ++ +  L GL+      WL + + V   Y 
Sbjct: 367 LLHKKLLRPLREGDGGGASQVYYQNAKL--NYMRLQLDGLKV--GQLWLSVIAAVVLNYT 422

Query: 458 S 458
           S
Sbjct: 423 S 423
>ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis elegans]
 pir||T21487 hypothetical protein F28C6.4 - Caenorhabditis elegans
 emb|CAA92675.1| (Z68315) Similarity to Yeast hypothetical protein YJ10
           (SW:YJ10_YEAST)~cDNA EST yk160e12.5 comes from this
           gene~cDNA EST yk160e12.3 comes from this gene~cDNA EST
           yk317h4.3 comes from this gene~cDNA EST yk317h4.5 comes
           from this gene [Caenorhabditis ele>
          Length = 795

 Score =  301 bits (765), Expect = 3e-80
 Identities = 71/386 (18%), Positives = 135/386 (34%), Gaps = 53/386 (13%)

Query: 3   GRLLLLGILF-----HVVFLKSIFDIYFVTPLIH-----GMKQYSAGEAPAKRLFLIVGD 52
           G+  +  +L       +V+     DI    P        G ++ S+      RL  +V D
Sbjct: 56  GKFWISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSP----RLVFMVID 111

Query: 53  GLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFY 112
             R   L    S     + +         I + +     ++ R+PT + P   A + G  
Sbjct: 112 AFRLSFLTSSKSPMSFTKSE---------ITKKSAKLFDAYARMPTVTLPRITAYLTGTL 162

Query: 113 EDVSAVTKGWKKNPVNFDSVFNQ----SRHTYSFGSEDILPMFSEGASDPSRVDTFMYSS 168
                V        +   +  ++     +  + FG +  + +          V +F    
Sbjct: 163 PSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFV-- 220

Query: 169 ELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHP 228
                 S+   +D  V   LD  L+ +          +       LH LG+D IGH+   
Sbjct: 221 ------SDYTDVDNNVTRHLDTELSNT----------NHSWDALILHYLGLDHIGHSLGG 264

Query: 229 DSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTP 288
            S +  E ++ +D  I  +   + +  + D  S  +   DHGM+  GSHG  + D TR P
Sbjct: 265 SSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVP 324

Query: 289 IIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQ 348
           ++ W    +    E N  +       + +  +   I+Q D+++ +  +  +  P+ S G 
Sbjct: 325 VVIW----KFGREEGNKNYG----NQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGI 376

Query: 349 IPLDYLDCSSRRKAEVALMNALEIGE 374
             ++Y         E        I +
Sbjct: 377 SLINYFSDDEEEYFEKQHNQFRRIVQ 402
 Score = 37.2 bits (86), Expect = 1.4
 Identities = 18/58 (31%), Positives = 24/58 (41%)

Query: 794 SLFFYIFINVAFFGTGNVASLSTFALDSVKRFIPVFNPVTQGALLMYTILVPFIALSA 851
           S+ F      +FF TGN  SLST +L S    +  + P+  G  LM       I    
Sbjct: 676 SVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFLC 733
>gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melanogaster]
          Length = 475

 Score =  295 bits (748), Expect = 3e-78
 Identities = 77/367 (20%), Positives = 135/367 (35%), Gaps = 47/367 (12%)

Query: 188 LDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDS---VEYVENIQ------ 238
            D +  +S        M+         + + +   G     DS    +  E +       
Sbjct: 122 FDTVFNRSRN------MIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKLTCDKWAF 175

Query: 239 -YIDGKIQELVDKMNNYYNNDGASSWVFTAD-----HGMSDFGSHGDGNLDNTRTPIIAW 292
             ++  ++  VD +  + N   A  +V+ AD     H      +HG G+     TP+  W
Sbjct: 176 DKVENFLRN-VDNVREWRNYKPAVFFVYLADMDIAAHRFKPLRAHGSGSPLEVETPLFMW 234

Query: 293 GAGIQSPTHEKNYGHDEYSLPWNLTEIKRI-DIQQADIAALMSYLVGLNFPVNSVGQIPL 351
           GAG++          DE     N  E   I  + Q  +A LMS L+GL  P N++  +P+
Sbjct: 235 GAGVKR---------DEIDAEANFPEKPNISQVDQTQLAPLMSSLIGLPPPKNNLALMPV 285

Query: 352 DYLDCSSRRKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVI 411
            YL+ S   +A    +N L++  Q  +    + + +IF   Y  L  + E+     +   
Sbjct: 286 GYLNVSDEYQAVALHLNVLQLLSQAEI-LIGRHEKAIF---YKWLPKFKELHIGVIDQYA 341

Query: 412 A----DIESGEYEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFV 467
           A        G    A+E C  + +     L Y  +Y    L       Y+ W     C +
Sbjct: 342 AQFDILKSEGNLTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIW---FYCLL 398

Query: 468 FSLN-IEPSSKIVKP--VSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLI 524
             L  +    K+ +   ++V   +   I  LLI +   +Q  P     Y + P   L + 
Sbjct: 399 LQLTRLSKKEKMQRRGFMTVSTLILAMIGILLIAMME-LQKVPHIAAFYLILPVGMLIMA 457

Query: 525 HSIFPNT 531
            +  P+ 
Sbjct: 458 QAERPDI 464
 Score =  198 bits (501), Expect = 3e-49
 Identities = 68/234 (29%), Positives = 107/234 (45%), Gaps = 28/234 (11%)

Query: 3   GRLLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSA-----GEAPAKRLFLIVGDGLRPD 57
            +L    ++ H++ + +I + YF   L+  +           E PA RL + V DGLR  
Sbjct: 2   WKL--QALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAA 59

Query: 58  KLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSA 117
             L  +   V         P L+ I +  G  G+S T  PT +RPGH+A+ AGF+ED +A
Sbjct: 60  TFLANNGSDV---------PDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAA 110

Query: 118 VTKGWKKNPVNFDSVFNQSRHTYSFGSEDILPMF---SEGASDPSRVDTFMYSSELEDFS 174
                  NP +FD+VFN+SR+   +    I+  F   S G   P R D++M     E  +
Sbjct: 111 SLMHLCYNPGDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGG-APLRFDSYMERDLPEKLT 169

Query: 175 SNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHP 228
                 D+W FD+++  L        + +  +    VFF++L  +D   H   P
Sbjct: 170 -----CDKWAFDKVENFL---RNVDNVREWRNYKPAVFFVYLADMDIAAHRFKP 215
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  292 bits (741), Expect = 2e-77
 Identities = 75/395 (18%), Positives = 142/395 (34%), Gaps = 61/395 (15%)

Query: 5   LLLLGILFHVVFLK-SIFDIYFVTPLIHG-------MKQYS---------AGEAPAK-RL 46
             + GIL  ++ L   +F  + V P + G          +              P K RL
Sbjct: 14  FTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRL 73

Query: 47  FLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGV-SHTRVPTESRPGHV 105
              V DGL  + +L     K   +    + P+ +S++ N    G  +    PT + P   
Sbjct: 74  LYQVIDGLPAEFVLGKDG-KPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLK 132

Query: 106 ALIAGFYEDVSAVTKGWKKNPVNFDSVFNQ----SRHTYSFGSEDILPMFSEGASDPSRV 161
           A+++G       V   +    +  D++  Q           G E  L +F         V
Sbjct: 133 AMVSGAIGGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGV 192

Query: 162 DTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDT 221
            +F           + + +D  V   L + L               D  +  LH LG+D 
Sbjct: 193 SSFFV--------KDTVQVDRNVSRHLPDELN------------SDDWNLLILHYLGLDH 232

Query: 222 IGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNND-GASSWVFTADHGMSDFGSHGDG 280
           +GH    +S      ++ +D  ++ +  +     ++D G +  +  +DHGM++ G+HG  
Sbjct: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292

Query: 281 NLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLN 340
           + + T + ++  G          N    +Y+   N          Q D+A  ++ L G+ 
Sbjct: 293 SYEETDSLMLFIG---------LNSNISDYASATNNVAF------QVDLAPTLALLFGVP 337

Query: 341 FPVNSVGQIPLDYLDCSSRR-KAEVALMNALEIGE 374
            P N+VG +    L       +     +N+ ++  
Sbjct: 338 IPKNNVGVLVPGTLCSLRDFEQLRALELNSWQLLR 372
>dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus]
          Length = 876

 Score =  279 bits (707), Expect = 2e-73
 Identities = 38/313 (12%), Positives = 85/313 (27%), Gaps = 42/313 (13%)

Query: 31  HGMKQYSA----GEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNN 86
              +               + L   DG R + L       ++          L S     
Sbjct: 147 SSQEPQCPEGFDQPP----VILFSMDGFRAEYL--QTWSTLLPNINKLKTCGLHS----- 195

Query: 87  GTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSV----FNQSRHTYSF 142
                     PT++ P H  ++ G Y +   +      +     +       +S   +  
Sbjct: 196 ---KYMRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWS 252

Query: 143 GSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELW 202
           G    L    +G     +  ++ +     D + NG      ++      +        L 
Sbjct: 253 GQPIWLTAMYQG----LKAASYYWPGS--DVAVNGSFP--NIYRNYSNSVPYESRIATLL 304

Query: 203 DMLH----RDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNND 258
             L          + +++   D+ GH   P S   ++ +Q +D     L++ +     ++
Sbjct: 305 QWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHN 364

Query: 259 GASSWVFTADHGMSDFGSHGD----GNLDNTRTPIIAW-GAGIQSPTHEKNYGHDEYSLP 313
              + +  ADHGM                        + G   +  T         ++  
Sbjct: 365 C-VNIIVLADHGMDQTSCDRVEYMTDYFPEIN--FYMYQGPAPRIRTRNIPQDFFTFNSE 421

Query: 314 WNLTEIKRIDIQQ 326
             + ++      Q
Sbjct: 422 EIVRDLSCRKSDQ 434
>ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus norvegicus]
 gb|AAB61535.1| (U78787) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  279 bits (707), Expect = 2e-73
 Identities = 38/313 (12%), Positives = 85/313 (27%), Gaps = 42/313 (13%)

Query: 31  HGMKQYSA----GEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNN 86
              +               + L   DG R + L       ++          L S     
Sbjct: 147 SSQEPQCPEGFDQPP----VILFSMDGFRAEYL--QTWSTLLPNINKLKTCGLHS----- 195

Query: 87  GTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSV----FNQSRHTYSF 142
                     PT++ P H  ++ G Y +   +      +     +       +S   +  
Sbjct: 196 ---KYMRAVYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWS 252

Query: 143 GSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELW 202
           G    L    +G     +  ++ +     D + NG      ++      +        L 
Sbjct: 253 GQPIWLTAMYQG----LKAASYYWPGS--DVAVNGSFP--NIYRNYSNSVPYESRIATLL 304

Query: 203 DMLH----RDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNND 258
             L          + +++   D+ GH   P S   ++ +Q +D     L++ +     ++
Sbjct: 305 QWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHN 364

Query: 259 GASSWVFTADHGMSDFGSHGD----GNLDNTRTPIIAW-GAGIQSPTHEKNYGHDEYSLP 313
              + +  ADHGM                        + G   +  T         ++  
Sbjct: 365 C-VNIIVLADHGMDQTSCDRVEYMTDYFPEIN--FYMYQGPAPRIRTRNIPQDFFTFNSE 421

Query: 314 WNLTEIKRIDIQQ 326
             + ++      Q
Sbjct: 422 EIVRDLSCRKSDQ 434
>gb|AAB61536.1| (U78788) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  277 bits (704), Expect = 4e-73
 Identities = 38/313 (12%), Positives = 85/313 (27%), Gaps = 42/313 (13%)

Query: 31  HGMKQYSA----GEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNN 86
              +               + L   DG R + L       ++          L S     
Sbjct: 147 SSQEPQCPEGFDQPP----VILFSMDGFRAEYL--QTWSTLLPNINKLKTCGLHS----- 195

Query: 87  GTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSV----FNQSRHTYSF 142
                     PT++ P H  ++ G Y +   +      +     +       +S   +  
Sbjct: 196 ---KYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWS 252

Query: 143 GSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELW 202
           G    L    +G     +  ++ +     D + NG      ++      +        L 
Sbjct: 253 GQPIWLTAMYQG----LKAASYYWPGS--DVAVNGSFP--NIYRNYSNSVPYESRIATLL 304

Query: 203 DMLH----RDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNND 258
             L          + +++   D+ GH   P S   ++ +Q +D     L++ +     ++
Sbjct: 305 QWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHN 364

Query: 259 GASSWVFTADHGMSDFGSHGD----GNLDNTRTPIIAW-GAGIQSPTHEKNYGHDEYSLP 313
              + +  ADHGM                        + G   +  T         ++  
Sbjct: 365 C-VNIIVLADHGMDQTSCDRVEYMTDYFPEIN--FYMYQGPAPRIRTRNIPQDFFTFNSE 421

Query: 314 WNLTEIKRIDIQQ 326
             + ++      Q
Sbjct: 422 EIVRDLSCRKSDQ 434
>pir||A57080 cell surface antigen RB13-6 - rat
 emb|CAA88029.1| (Z47987) RB13-6 antigen [Rattus norvegicus]
          Length = 875

 Score =  274 bits (694), Expect = 7e-72
 Identities = 38/313 (12%), Positives = 85/313 (27%), Gaps = 42/313 (13%)

Query: 31  HGMKQYSA----GEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNN 86
              +               + L   DG R + L       ++          L S     
Sbjct: 147 SSQEPQCPEGFDQPP----VILFSMDGFRAEYL--QTWSTLLPNINKLKTCGLHS----- 195

Query: 87  GTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSV----FNQSRHTYSF 142
                     PT++ P H  ++ G Y +   +      +     +       +S   +  
Sbjct: 196 ---KYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWS 252

Query: 143 GSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELW 202
           G    L    +G     +  ++ +     D + NG      ++      +        L 
Sbjct: 253 GQPIWLTAMYQG----LKAASYYWLGS--DVAVNGSFP--NIYRNYSNSVPYESRIATLL 304

Query: 203 DMLH----RDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNND 258
             L          + +++   D+ GH   P S   ++ +Q +D     L++ +     ++
Sbjct: 305 QWLDLPKAERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHN 364

Query: 259 GASSWVFTADHGMSDFGSHGD----GNLDNTRTPIIAW-GAGIQSPTHEKNYGHDEYSLP 313
              + +  ADHGM                        + G   +  T         ++  
Sbjct: 365 C-VNIIVLADHGMDQTSCDRVEYMTDYFPEIN--FYMYQGPAPRIRTRNIPQDFFTFNSE 421

Query: 314 WNLTEIKRIDIQQ 326
             + ++      Q
Sbjct: 422 EIVRDLSCRKSDQ 434
>ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phosphodiesterase 3;
           phosphodiesterase I/nucleotide pyrophosphatase 3;
           phosphodiesterase-I beta; gp130RB13-6; bovine intestinal
           phosphodiesterase [Homo sapiens]
 gb|AAC51813.1| (AF005632) phosphodiesterase I/nucleotide pyrophosphatase beta
           [Homo sapiens]
          Length = 875

 Score =  273 bits (692), Expect = 1e-71
 Identities = 37/313 (11%), Positives = 86/313 (26%), Gaps = 41/313 (13%)

Query: 31  HGMKQYSA----GEAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNN 86
              +               + L   DG R + L     + ++          + S     
Sbjct: 146 TAQQSQCPEGFDLPP----VILFSMDGFRAEYLY--TWDTLMPNINKLKTCGIHS----- 194

Query: 87  GTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVF----NQSRHTYSF 142
                     PT++ P H  ++ G Y +   +      +     +       Q+   +  
Sbjct: 195 ---KYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWH 251

Query: 143 GSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELW 202
           G    L    +G     +  T+ +       + NG      ++   +  +        L 
Sbjct: 252 GQPMWLTAMYQG----LKAATYFWPGSEV--AINGSFPS--IYMPYNGSVPFEERISTLL 303

Query: 203 DMLH----RDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNND 258
             L          + ++    D+ GH   P S   ++ +Q +D     L++ +     ++
Sbjct: 304 KWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNLHN 363

Query: 259 GASSWVFTADHGMSDFGSHG----DGNLDNTRTPIIAW-GAGIQSPTHEKNYGHDEYSLP 313
              + +  ADHGM     +                  + G   +   H   +    ++  
Sbjct: 364 C-VNIILLADHGMDQTYCNKMEYMTDYFPRINF-FYMYEGPAPRIRAHNIPHDFFSFNSE 421

Query: 314 WNLTEIKRIDIQQ 326
             +  +      Q
Sbjct: 422 EIVRNLSCRKPDQ 434
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  270 bits (684), Expect = 9e-71
 Identities = 70/373 (18%), Positives = 131/373 (34%), Gaps = 63/373 (16%)

Query: 7   LLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAG---------------EAPAKRLFLIVG 51
           +L +  +++    IF   F   L+   +  S                 +   +R+ LI+ 
Sbjct: 7   ILLVSINILLALFIFQNGF---LLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILV 63

Query: 52  DGLRPDKLLQPHSEKVIGEEQTYAAPFLRSI----IQNNGTFGVSHTRVPTESRPGHVAL 107
           D LR D L+         +E+ Y    +++I       N + G      PT +     AL
Sbjct: 64  DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKAL 123

Query: 108 IAGFYEDVSAVTKGWKKNP-VNFDSVFNQ----SRHTYSFGSEDILPMFSEGASDPSRVD 162
             G           +  +  ++ DS   Q     ++    G +  L +F    S  +  D
Sbjct: 124 TTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTAAYD 183

Query: 163 TFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWD-MLHRDKIVFFLHLLGIDT 221
           +F  +      + +  +  +  F +    +    E   L D ML+ +  +   H LG+D 
Sbjct: 184 SFDINDLN---TVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDH 240

Query: 222 IGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGN 281
            GH   P      + ++ +D  I + ++ M +              DHGM+  G HG  +
Sbjct: 241 CGHKFGPSHPVMADTLRKMDRIIGQTIETMKSD-------------DHGMTSTGDHGGES 287

Query: 282 LDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNF 341
            +  R  I+     + S  H+                +    I Q DI   +S L+GL  
Sbjct: 288 ENEIRAGIL-----VHSKKHQI--------------ILPERPIHQIDIVPTISLLMGLPI 328

Query: 342 PVNSVGQIPLDYL 354
           P +++G +     
Sbjct: 329 PFSNLGTVITQLF 341
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  267 bits (676), Expect = 9e-70
 Identities = 55/360 (15%), Positives = 118/360 (32%), Gaps = 57/360 (15%)

Query: 41  APAKRLFLIVGDGLRPDK-LLQPHSEKVIGEEQTYAAPFLRSIIQN---NGTFGVSHTRV 96
               ++ ++V D L+ +  L + ++   +  E       L+ ++Q    +          
Sbjct: 74  PQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVV--LQELLQQNPDHARLMRFRADP 131

Query: 97  PTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQSRH----TYSFGSEDILPMFS 152
           PT +      L  G       +   +    +N D++ +Q           G      ++ 
Sbjct: 132 PTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTWTDLYP 191

Query: 153 EGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVF 212
                     +F           +   +D  +   L + L              +D  V 
Sbjct: 192 HRFKRSYSYPSFDI--------FDLDSVDNEILKHLPKELE------------SKDWQVL 231

Query: 213 FLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMS 272
             H LG+D  GH   P   E    +  ++  I+ +V  M      D  ++ +   DHGM+
Sbjct: 232 VAHFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAM------DNDTTLLVMGDHGMT 285

Query: 273 DFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQADIAAL 332
             G HG    D T   + A+    +   ++     +               +QQ D+   
Sbjct: 286 ASGDHGGDTDDETNALLFAYSKQHRFYGNDSGSDSEM--------------LQQIDLVPT 331

Query: 333 MSYLVGLNFPVNSVGQI---PLDYLDCSSRRKAEVALM----NALEIGEQYNLKSASKDQ 385
           ++ ++G+  P +++G +    +  L      K +  L+    NA +I   +   +    +
Sbjct: 332 LATILGVPIPYSNLGLVNFNIVPDLRVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKR 391
>pir||T33724 hypothetical protein - Zymomonas mobilis
 gb|AAC70363.1| (AF086791) unknown [Zymomonas mobilis]
          Length = 429

 Score =  251 bits (635), Expect = 5e-65
 Identities = 60/298 (20%), Positives = 100/298 (33%), Gaps = 41/298 (13%)

Query: 4   RLLLLGILFHVVFLKSIFDIYFVTPLIHG-MKQYSAGEAPAKRLFLIVGDGLRPDKLLQP 62
           +  + GIL  ++    +  ++         +   S        L LI  DG R D     
Sbjct: 12  KPWISGILSLLLGCAGLSVVHSDAIAATAHVTAQSKTP-----LILISIDGFRAD----- 61

Query: 63  HSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGW 122
                    +    P L S+ +N     V H   P+ + P H  L+ G Y D   +    
Sbjct: 62  -------YIKRGLTPNLVSLAENGSYAKVMHPSFPSITFPNHYTLVTGLYPDHHGIVGNN 114

Query: 123 KKNP-VNFDSVFNQSRHT-------YSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFS 174
             +  +  DS F  S H        +  G    +    +G        T  +     D  
Sbjct: 115 MDDAHITPDSHFKMSDHQAATDRRWWDEGEPLWVTAEKQGVVS----ATMFWPGSEADI- 169

Query: 175 SNGIVLDEWVFDRLDELLAQSLEDKELWDML----HRDKIVFFLHLLGIDTIGHNKHPDS 230
             G+  + W   + D  +  S    +++  L     +      L+   +D  GH   PDS
Sbjct: 170 -EGVRPEMW--RQFDSHVPFSERVDQVFSWLAYPKKKRPQFITLYFENVDHAGHLYGPDS 226

Query: 231 VEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTP 288
            E  +N+  ID  I +LV  +         ++ V  +DHGM+   S     L+    P
Sbjct: 227 QEVNDNLVKIDQTIGQLVQGLKQRGI---KANLVIVSDHGMAATSSDRVVALNKILDP 281
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  245 bits (621), Expect = 3e-63
 Identities = 49/286 (17%), Positives = 83/286 (28%), Gaps = 44/286 (15%)

Query: 10  ILFHVVFLKSIFDIYFV-------------TPLIHGMKQYSAGEAPAKRL-----FLIVG 51
           +LF   FL S F I+F+             T  +      +    P K+L      +I  
Sbjct: 1   MLFLSNFLSSSFLIFFIVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVVLMISC 60

Query: 52  DGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVS-HTRVPTESRPGHVALIAG 110
           DG R             G +     P +  +I              PT + P H ++  G
Sbjct: 61  DGFR------------FGYQFKTDTPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATG 108

Query: 111 FYEDVSAVTKGWKKNPVNFDSVFNQSRHT-YSFGSEDILPMFSEGASDPSRVDTFMYSSE 169
            Y     +      +PV  + VFN+     +  G    +       +   +  T+ + S 
Sbjct: 109 LYPAYHGIIMNKFTDPVTGE-VFNKGLQPKWWLGEPLWVTA----VNQGLKAVTYFWPSS 163

Query: 170 LEDFSSNGIVLDEWVFDRLDELLAQSLEDKE----LWDMLHRDKIVFFLHLLGIDTIGHN 225
               SS      E      +  +               +      +  L+    D  GHN
Sbjct: 164 EVLKSS--WTCPEGYCPHFNLSVPLEERVDSVLSHFDHLEDEVPDLLMLYFDEPDQSGHN 221

Query: 226 KHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGM 271
             PD       +  +D  I  ++  +            +   DHGM
Sbjct: 222 YGPDDPRVTTAVSRVDKMIGRVIKGLKQ-REIFDEVHVILLGDHGM 266
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  243 bits (615), Expect = 1e-62
 Identities = 43/275 (15%), Positives = 82/275 (29%), Gaps = 32/275 (11%)

Query: 7   LLGILFHVVFLKSIFDIYFVTPLIHGMK---QYSAGEAPAKRLFLIVGDGLRPDKLLQPH 63
           +  + F  +FL +       +  I         +    P   + LI  DG R        
Sbjct: 56  IAAVSFAFLFLSATSAAAGESKTIKITTTARSLTKLTHPI--VILISSDGFR-------- 105

Query: 64  SEKVIGEEQTYAAPFLRSIIQNNGTFGVS-HTRVPTESRPGHVALIAGFYEDVSAVTKGW 122
                G +     P +  +I N  +  +      PT + P H +++ G Y     +   +
Sbjct: 106 ----FGYQFKAPTPNIHRLINNGTSAELGLIPVFPTLTFPNHYSIVTGLYPPHHGIINNY 161

Query: 123 KKNPVNFDSVFNQSRHT--YSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVL 180
             +P+  D  F+ + H   +  G      +   G     +  T+ +              
Sbjct: 162 FVDPITGDK-FSMASHEPKWWLGEPLWETVAKHG----KKAATYFWPGSEVIK--PDWDC 214

Query: 181 DEWVFDRLDELLAQSLEDK---ELWDML-HRDKIVFFLHLLGIDTIGHNKHPDSVEYVEN 236
                   +  +            +D+  +   +   L+    D  GH   PD  E  + 
Sbjct: 215 PSNYCIHYNGSIPFEERVDTVISYFDLPINEIPVFMTLYFEDPDHQGHQVGPDDPEITQA 274

Query: 237 IQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGM 271
           +  ID  I  L+  +          +     DHGM
Sbjct: 275 VINIDKMIGRLIKGLE-KRGVFEDVNIFMVGDHGM 308
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  242 bits (613), Expect = 2e-62
 Identities = 45/280 (16%), Positives = 80/280 (28%), Gaps = 34/280 (12%)

Query: 6   LLLGILFHVVFLKSIFDIYFV---TPLIHGMKQYSAGEAPAKRL-----FLIVGDGLRPD 57
           L L  L ++  + +I     V   T  +      +    P K+L      +I  DG R  
Sbjct: 12  LSLIFLLNIFIVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNKPVVLMISCDGFR-- 69

Query: 58  KLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVS-HTRVPTESRPGHVALIAGFYEDVS 116
                      G +     P +  +I              PT + P H ++  G Y    
Sbjct: 70  ----------FGYQFKTDTPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATGLYPAYH 119

Query: 117 AVTKGWKKNPVNFDSVFNQSRHT-YSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS 175
            +      +PV  + VFN+     +  G    +       +   +  T+ +       SS
Sbjct: 120 GIIMNKFTDPVTGE-VFNKGLQPKWWLGEPLWVTA----VNQGLKAVTYFWPGSEVLKSS 174

Query: 176 NGIVLDEWVFDRLDELLAQSLEDKE----LWDMLHRDKIVFFLHLLGIDTIGHNKHPDSV 231
                 E      +  +               +      +  L+    D  GHN  PD  
Sbjct: 175 --WTCPEGYCPHFNLSVPLEERVDSVLSHFDHLEDEVPDLLMLYFDEPDQSGHNYGPDDP 232

Query: 232 EYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGM 271
                +  +D  I  ++  +            +   DHGM
Sbjct: 233 RVTTAVSRVDKMIGRVIKGLKQ-REIFDEVHVILLGDHGM 271
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  241 bits (610), Expect = 4e-62
 Identities = 43/279 (15%), Positives = 80/279 (28%), Gaps = 37/279 (13%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGEAPAKRL-----FLIVGDGLRPDKL 59
           L  L +   +V   ++      +P       Y     P K+L      LI  DG R    
Sbjct: 16  LYKLSLTVLIVLSVAVTANGSDSP-----SSYVRRPQPPKKLNKPVVLLISCDGFR---- 66

Query: 60  LQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVS-HTRVPTESRPGHVALIAGFYEDVSAV 118
                    G +     P +  +I              PT + P H ++  G Y     +
Sbjct: 67  --------FGYQFKTETPNIDLLISRGTEAKTGLIPVFPTMTFPNHYSIATGLYPASHGI 118

Query: 119 TKGWKKNPVNFDSVFNQSRHT-YSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNG 177
                 +PV+ + +FN++ +  +  G    +       +      T+ +        S  
Sbjct: 119 IMNKFTDPVSGE-LFNRNLNPKWWLGEPLWVTA----VNQGLMAATYFWPGADVHKGS-- 171

Query: 178 IVLDEWVFD-RLDELLAQSLEDKE---LWDML-HRDKIVFFLHLLGIDTIGHNKHPDSVE 232
               +       +  +            +D+          L+    D  GH   PD   
Sbjct: 172 WNCPKGFCKAPYNVSVPLEERVDTILNYFDLPEREIPDFMALYFDEPDIQGHEYGPDDPR 231

Query: 233 YVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGM 271
             E +  +D  I  ++  +            +   DHGM
Sbjct: 232 VTEAVSKVDKMIGRIIMGLE-KRKVFSDVHVILLGDHGM 269
>gb|AAD05192.1| (AC005587) phosphodiesterase I beta [Homo sapiens]
          Length = 687

 Score =  235 bits (594), Expect = 4e-60
 Identities = 31/255 (12%), Positives = 73/255 (28%), Gaps = 23/255 (9%)

Query: 85  NNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVF----NQSRHTY 140
                       PT++ P H  ++ G Y +   +      +     +       Q+   +
Sbjct: 2   CGIHSKYMRAMYPTKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAW 61

Query: 141 SFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKE 200
             G    L    +G     +  T+ +       + NG      ++   +  +        
Sbjct: 62  WHGQPMWLTAMYQG----LKAATYFWPGSEV--AINGSFPS--IYMPYNGSVPFEERIST 113

Query: 201 LWDMLH----RDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYN 256
           L   L          + ++    D+ GH   P S   ++ +Q +D     L++ +     
Sbjct: 114 LLKWLDLPKAERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQRNL 173

Query: 257 NDGASSWVFTADHGMSDFGSHG----DGNLDNTRTPIIAW-GAGIQSPTHEKNYGHDEYS 311
           ++   + +  ADHGM     +                  + G   +   H   +    ++
Sbjct: 174 HNC-VNIILLADHGMDQTYCNKMEYMTDYFPRINF-FYMYEGPAPRIRAHNIPHDFFSFN 231

Query: 312 LPWNLTEIKRIDIQQ 326
               +  +      Q
Sbjct: 232 SEEIVRNLSCRKPDQ 246
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  233 bits (590), Expect = 1e-59
 Identities = 42/291 (14%), Positives = 82/291 (27%), Gaps = 46/291 (15%)

Query: 5   LLLLGILFHV----VFLKSIFDIYFVTPLIHGMKQYSAGEAPAKR-------------LF 47
              L ++  +        +        P++   +   +      R             + 
Sbjct: 53  FTSLLLVTCIALSAASAFAFLFFSSQKPVLSLNQISKS--PAFDRSVARPLKKLDKPVVL 110

Query: 48  LIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVS-HTRVPTESRPGHVA 106
           LI  DG R             G +     P +  +I N            PT + P H +
Sbjct: 111 LISSDGFR------------FGYQFKTKLPSIHRLIANGTEAETGLIPVFPTLTFPNHYS 158

Query: 107 LIAGFYEDVSAVTKGWKKNPVNFDSVFNQSRH--TYSFGSEDILPMFSEGASDPSRVDTF 164
           ++ G Y     +      +P    +VF  + H   +  G      +     +   +  T+
Sbjct: 159 IVTGLYPAYHGIINNHFVDPETG-NVFTMASHEPEWWLGEPLWETV----VNQGLKAATY 213

Query: 165 MYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDK---ELWDML-HRDKIVFFLHLLGID 220
            +        S      + +    +  +            +D+  +       L+    D
Sbjct: 214 FWPGSEVHKGS--WNCPQGLCQNYNGSVPFDDRVDTILSYFDLPSNEIPSFMTLYFEDPD 271

Query: 221 TIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGM 271
             GH   PD  +  E +  ID  I  L+D +          + +   DHGM
Sbjct: 272 HQGHQVGPDDPQITEAVVNIDRLIGRLIDGLE-KRGIFEDVTMIMVGDHGM 321
>ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyrophosphatase 2;
           phosphodiesterase I/nucleotide pyrophosphatase 2
           (autotaxin) [Rattus norvegicus]
 pir||A55453 plasma cell membrane glycoprotein PC-1, brain specific - rat
 dbj|BAA05910.1| (D28560) phosphodiesterase I [Rattus norvegicus]
          Length = 885

 Score =  233 bits (589), Expect = 1e-59
 Identities = 49/293 (16%), Positives = 86/293 (28%), Gaps = 42/293 (14%)

Query: 40  EAPAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTE 99
             P   L +   DG R          KV+        P +  +         +    PT+
Sbjct: 160 PPP---LIIFSVDGFRAS--YMKKGSKVM--------PNIEKLRSCGTHVPYTRPVYPTK 206

Query: 100 SRPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFNQSR----HTYSFGSEDILPMFSEGA 155
           + P    L  G Y +   +      +PV   S   + R    H +  G    +    +G 
Sbjct: 207 TFPNLYTLATGLYPESHGIVGNSMYDPVFDASFHLRGREKFNHRWWGGQPLWITATKQGV 266

Query: 156 SDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLH 215
              +   +     E    +     + +W+                L D  +    V+  +
Sbjct: 267 RAGTFFWSVSIPHERRILT-----ILQWL---------------SLPD--NERPSVYAFY 304

Query: 216 LLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFG 275
               D  GH   P   E    ++ ID  + +L+D +     +    + +F  DHGM D  
Sbjct: 305 SEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRC-VNVIFVGDHGMEDVT 363

Query: 276 SHGDGNLDN--TRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQ 326
                 L N  T    I    G       K+  + +Y     +  +      Q
Sbjct: 364 CDRTEFLSNYLTNVDDITLVPGTLGRIRAKSINNSKYDPKTIIANLTCKKPDQ 416
>dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 179

 Score =  233 bits (589), Expect = 2e-59
 Identities = 178/178 (100%), Positives = 178/178 (100%)

Query: 206 HRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVF 265
           HRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVF
Sbjct: 1   HRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVF 60

Query: 266 TADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQ 325
           TADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQ
Sbjct: 61  TADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQ 120

Query: 326 QADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASK 383
           QADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASK
Sbjct: 121 QADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLKSASK 178
>gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase/phosphodiesterase 2 [Mus
           musculus]
          Length = 862

 Score =  229 bits (579), Expect = 2e-58
 Identities = 46/252 (18%), Positives = 79/252 (31%), Gaps = 42/252 (16%)

Query: 41  APAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTES 100
            P   L +   DG R          KV+        P +  +              PT++
Sbjct: 163 PP---LIIFSVDGFRAS--YMKKGSKVM--------PNIEKLRSCGTHAPYMRPVYPTKT 209

Query: 101 RPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFN-QSR----HTYSFGSEDILPMFSEGA 155
            P    L  G Y +   +      +PV FD+ F+ + R    H +  G    +    +G 
Sbjct: 210 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 268

Query: 156 SDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLH 215
              +   +     E    +     + +W+                L D  +    V+  +
Sbjct: 269 RAGTFFWSVSIPHERRILT-----ILQWL---------------SLPD--NERPSVYAFY 306

Query: 216 LLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFG 275
               D  GH   P   E    ++ ID  + +L+D +     +    + +F  DHGM D  
Sbjct: 307 SEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRC-VNVIFVGDHGMEDVT 365

Query: 276 SHGDGNLDNTRT 287
                 L N  T
Sbjct: 366 CDRTEFLSNYLT 377
>ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyrophosphatase 2 [Mus
           musculus]
 gb|AAD46480.1|AF123542_1 (AF123542) phosphodiesterase I/nucleotide pyrophosphatase [Mus
           musculus]
          Length = 862

 Score =  228 bits (578), Expect = 2e-58
 Identities = 46/252 (18%), Positives = 79/252 (31%), Gaps = 42/252 (16%)

Query: 41  APAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTES 100
            P   L +   DG R          KV+        P +  +              PT++
Sbjct: 163 PP---LIIFSVDGFRAS--YMKKGSKVM--------PNIEKLRSCGTHAPYMRPVYPTKT 209

Query: 101 RPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFN-QSR----HTYSFGSEDILPMFSEGA 155
            P    L  G Y +   +      +PV FD+ F+ + R    H +  G    +    +G 
Sbjct: 210 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 268

Query: 156 SDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLH 215
              +   +     E    +     + +W+                L D  +    V+  +
Sbjct: 269 RAGTFFWSVSIPHERRILT-----ILQWL---------------SLPD--NERPSVYAFY 306

Query: 216 LLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFG 275
               D  GH   P   E    ++ ID  + +L+D +     +    + +F  DHGM D  
Sbjct: 307 SEQPDFSGHKYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRC-VNVIFVGDHGMEDVT 365

Query: 276 SHGDGNLDNTRT 287
                 L N  T
Sbjct: 366 CDRTEFLSNYLT 377
>dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens]
          Length = 863

 Score =  227 bits (575), Expect = 6e-58
 Identities = 52/293 (17%), Positives = 89/293 (29%), Gaps = 44/293 (15%)

Query: 41  APAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTES 100
            P   L +   DG R          KV+        P +  +              PT++
Sbjct: 164 PP---LIIFSVDGFRAS--YMKKGSKVM--------PNIEKLRSCGTHSPYMRPVYPTKT 210

Query: 101 RPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFN-QSR----HTYSFGSEDILPMFSEGA 155
            P    L  G Y +   +      +PV FD+ F+ + R    H +  G    +    +G 
Sbjct: 211 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 269

Query: 156 SDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLH 215
              +   + +   E    +     + +W+                L D  H    V+  +
Sbjct: 270 KAGTFFWSVVIPHERRILT-----ILQWL---------------TLPD--HERPSVYAFY 307

Query: 216 LLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFG 275
               D  GH   P   E    ++ ID  + +L+D +     +    + +F  DHGM D  
Sbjct: 308 SEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRC-VNVIFVGDHGMEDVT 366

Query: 276 SHGDGNLDN--TRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQ 326
                 L N  T    I    G       K   + +Y     +  +      Q
Sbjct: 367 CDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQ 419
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  227 bits (575), Expect = 6e-58
 Identities = 49/280 (17%), Positives = 84/280 (29%), Gaps = 42/280 (15%)

Query: 12  FHVVFLKS-------IFDIYFVTPL------IHGMKQYSAGEAPAKRLFLIVGDGLRPDK 58
            H++   +       +  I   TPL          +     E P   + LI  DG R   
Sbjct: 47  LHLLLTAALAVATSYLLLILPRTPLSAAPAPAAAARAQVKLEKPV--VILISSDGFR--- 101

Query: 59  LLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSH-TRVPTESRPGHVALIAGFYEDVSA 117
                     G +   A P +  +I N  +         PT + P H ++  G Y     
Sbjct: 102 ---------FGYQHKAATPHIHRLIGNGTSAATGLVPIFPTLTFPNHYSIATGLYPSSHG 152

Query: 118 VTKGWKKNPVNFDSVFNQSRHT--YSFGSEDILPMFSEGASDPSRVDTFMYSSELEDFSS 175
           +   +  +P++ D  F  S H   +  G    +    +G        T+ +        S
Sbjct: 153 IINNYFPDPISGD-YFTMSSHEPKWWLGEPLWVTAADQGIQ----AATYFWPGSEVKKGS 207

Query: 176 NGIVLDEWVFDRLDELLAQSLEDKE---LWDMLHRD-KIVFFLHLLGIDTIGHNKHPDSV 231
                D+      +  +            +D+   +      L+    D  GH   PD  
Sbjct: 208 -WDCPDK-YCRHYNGSVPFEERVDAILGYFDLPSDEMPQFLTLYFEDPDHQGHQVGPDDP 265

Query: 232 EYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGM 271
              E +  ID  I  L+  +          + +   DHGM
Sbjct: 266 AITEAVVRIDEMIGRLIAGLEE-RGVFEDVNVILVGDHGM 304
>ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phosphodiesterase 2
           (autotaxin); Phosphodiesterase I/nucleotide
           pyrophosphatase 2; autotaxin; phosphodiesterase
           I/nucleotide pyrophosphatase 2 (autotaxin) [Homo
           sapiens]
 gb|AAB00855.1| (L46720) autotaxin-t [Homo sapiens]
          Length = 863

 Score =  227 bits (575), Expect = 6e-58
 Identities = 52/293 (17%), Positives = 89/293 (29%), Gaps = 44/293 (15%)

Query: 41  APAKRLFLIVGDGLRPDKLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTES 100
            P   L +   DG R          KV+        P +  +              PT++
Sbjct: 164 PP---LIIFSVDGFRAS--YMKKGSKVM--------PNIEKLRSCGTHSPYMRPVYPTKT 210

Query: 101 RPGHVALIAGFYEDVSAVTKGWKKNPVNFDSVFN-QSR----HTYSFGSEDILPMFSEGA 155
            P    L  G Y +   +      +PV FD+ F+ + R    H +  G    +    +G 
Sbjct: 211 FPNLYTLATGLYPESHGIVGNSMYDPV-FDATFHLRGREKFNHRWWGGQPLWITATKQGV 269

Query: 156 SDPSRVDTFMYSSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLH 215
              +   + +   E    +     + +W+                L D  H    V+  +
Sbjct: 270 KAGTFFWSVVIPHERRILT-----ILQWL---------------TLPD--HERPSVYAFY 307

Query: 216 LLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFG 275
               D  GH   P   E    ++ ID  + +L+D +     +    + +F  DHGM D  
Sbjct: 308 SEQPDFSGHKYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRC-VNVIFVGDHGMEDVT 366

Query: 276 SHGDGNLDN--TRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQQ 326
                 L N  T    I    G       K   + +Y     +  +      Q
Sbjct: 367 CDRTEFLSNYLTNVDDITLVPGTLGRIRSKFSNNAKYDPKAIIANLTCKKPDQ 419
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  210 bits (532), Expect = 7e-53
 Identities = 72/390 (18%), Positives = 130/390 (32%), Gaps = 53/390 (13%)

Query: 5   LLLLGILFHVVFLKSIFDIYFVTPLIHGMKQYSAGE-------APAKRLFLIVGDGLRPD 57
              L     +  L  IF  +    ++ G+ +    +        P ++L  ++ D LR D
Sbjct: 6   FTCLSCAQLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSD 65

Query: 58  KLLQPHSEKVIGEEQTYAAPFLRSIIQNNGTFGV-SHTRVPTESRPGHVALIAGFYEDVS 116
            L                   +   +     +G  S    PT + P   ++  G      
Sbjct: 66  FLFDSQISHFN---------NVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFI 116

Query: 117 AVTKGWKKNP-----VNFDSVFNQ----SRHTYSFGSEDILPMFSEG-ASDPSRVDTFMY 166
            +     ++         DS   Q    +      G +  L +F +          +F  
Sbjct: 117 DLLLNVAQDIDSNDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFV 176

Query: 167 SSELEDFSSNGIVLDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNK 226
                   S+   +D  V   L   L Q                V  LH LG+D IGH  
Sbjct: 177 --------SDFTQVDNNVTRNLPGKLFQEW----------AQWDVAILHYLGLDHIGHKD 218

Query: 227 HPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTR 286
            P S       Q +D  ++ + D++   + +D  +      DHGM++ G+HG  +   T 
Sbjct: 219 GPHSKFMAAKHQEMDSILKSIYDEVLE-HEDDDDTLICVLGDHGMNELGNHGGSSAGETS 277

Query: 287 TPIIAWGAGIQSPTHEKNYGHDEYSLP----WNLTEIKRIDIQQADIAALMSYLVGLNFP 342
             ++     +      ++  +    +     WN   ++   +QQ DI   ++ L G+  P
Sbjct: 278 AGLLFLSPKLAQFARPESQVNYTLPINASPDWNFQYLE--TVQQIDIVPTIAALFGMPIP 335

Query: 343 VNSVGQIPLDYLDCSSRRKAEVALMNALEI 372
           +NSVG I  D+L      K      N + +
Sbjct: 336 MNSVGIIIPDFLQLLP-NKLASMKENFMHL 364
CPU time:   288.90 user secs.	    3.31 sys. secs	  292.21 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.316    0.180    0.492 

Gapped
Lambda     K      H
   0.270   0.0631    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 693853412
Number of Sequences: 887402
Number of extensions: 41069374
Number of successful extensions: 186913
Number of sequences better than 10.0: 1259
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 1157
Number of HSP's that attempted gapping in prelim test: 184161
Number of HSP's gapped (non-prelim): 2932
length of query: 935
length of database: 277,845,442
effective HSP length: 55
effective length of query: 880
effective length of database: 229,038,332
effective search space: 201553732160
effective search space used: 201553732160
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.7 bits)
S2: 78 (34.4 bits)