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GPI Anchor Biosynthesis Report: AAF56048.1 (PIG-N family, Drosophila melanogaster)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (919 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 5

Distribution of 52 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 1091 0.0
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 1007 0.0
ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class ... 981 0.0
gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melano... 871 0.0
pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragme... 843 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 836 0.0
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 833 0.0
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 830 0.0
pir||T40715 hypothetical protein SPBC839.08c - fission yeast (S... 811 0.0
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 708 0.0
ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster] 677 0.0
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 535 e-150
gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caeno... 529 e-149
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 493 e-138
gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melano... 478 e-133
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 441 e-122
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 404 e-111
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 377 e-103
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 375 e-102
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 348 3e-94
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 338 3e-91
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 320 7e-86
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 309 2e-82
gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melan... 302 1e-80
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 294 4e-78
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 272 2e-71
ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phos... 254 4e-66
gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphat... 254 5e-66
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 251 4e-65
pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse 250 9e-65
ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyro... 250 9e-65
gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphata... 250 9e-65
gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattu... 249 1e-64
sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodieste... 248 4e-64
ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyro... 243 9e-63
dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located... 242 2e-62
pir||A39216 plasma cell membrane glycoprotein PC-1 - human >gi|7... 242 2e-62
gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase... 240 6e-62
ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyro... 240 7e-62
ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phos... 239 1e-61
dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens] 239 1e-61
ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phos... 239 1e-61
emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucle... 238 3e-61
ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]... 212 2e-53
dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharom... 209 2e-52
ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campyl... 195 2e-48
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 184 8e-45
Alignments
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score = 1091 bits (2792), Expect = 0.0
 Identities = 919/919 (100%), Positives = 919/919 (100%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS
Sbjct: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60

Query: 61  VLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLTWNPSTFD 120
           VLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLTWNPSTFD
Sbjct: 61  VLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLTWNPSTFD 120

Query: 121 SVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMT 180
           SVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMT
Sbjct: 121 SVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMT 180

Query: 181 NEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFN 240
           NEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFN
Sbjct: 181 NEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFN 240

Query: 241 DSRTAYLMTADYGISLHGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQ 300
           DSRTAYLMTADYGISLHGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQ
Sbjct: 241 DSRTAYLMTADYGISLHGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQ 300

Query: 301 LEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRH 360
           LEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRH
Sbjct: 301 LEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRH 360

Query: 361 EDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYYHGY 420
           EDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYYHGY
Sbjct: 361 EDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYYHGY 420

Query: 421 YHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLELMILQ 480
           YHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLELMILQ
Sbjct: 421 YHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLELMILQ 480

Query: 481 RVPHLTAFYLLLPFGILILALAERPCQDRDLMCQFPVLHLVGIVMPGVLLILMAFHNSHI 540
           RVPHLTAFYLLLPFGILILALAERPCQDRDLMCQFPVLHLVGIVMPGVLLILMAFHNSHI
Sbjct: 481 RVPHLTAFYLLLPFGILILALAERPCQDRDLMCQFPVLHLVGIVMPGVLLILMAFHNSHI 540

Query: 541 GLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYIGNSH 600
           GLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYIGNSH
Sbjct: 541 GLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYIGNSH 600

Query: 601 VVYFSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYL 660
           VVYFSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYL
Sbjct: 601 VVYFSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYL 660

Query: 661 LFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESF 720
           LFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESF
Sbjct: 661 LFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESF 720

Query: 721 SYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFF 780
           SYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFF
Sbjct: 721 SYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFF 780

Query: 781 NFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFL 840
           NFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFL
Sbjct: 781 NFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFL 840

Query: 841 MNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKKDKPTP 900
           MNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKKDKPTP
Sbjct: 841 MNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKKDKPTP 900

Query: 901 RAPVQAVTNNANLAQDSQA 919
           RAPVQAVTNNANLAQDSQA
Sbjct: 901 RAPVQAVTNNANLAQDSQA 919
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score = 1007 bits (2576), Expect = 0.0
 Identities = 220/935 (23%), Positives = 429/935 (45%), Gaps = 58/935 (6%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           ++    L++H +   SI  IYF S ++  + P  T     L PPA RLV+FV DGLRA +
Sbjct: 3   LFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFT----PLPPPAKRLVLFVADGLRADT 58

Query: 61  VL---ADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW-- 114
           +     D  S  P +R + + +   G+S    PT +RPGH+A+  GF ED +A    W  
Sbjct: 59  LYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKE 118

Query: 115 NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFAR---SDISDRLRLDQWT 171
           NP  FDS+FN S+    W   ++  +F    +G     +   A+       D  +LD W 
Sbjct: 119 NPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWV 178

Query: 172 FDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGI 228
           FDKV++F    +N Q L    +   V+FF++L  +D   H H P+S  +++ +     G+
Sbjct: 179 FDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDDGV 238

Query: 229 RQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPG 284
           ++   +F+  + +D +TA++ T+D+G++    HG G      TPF+ WGAG+K       
Sbjct: 239 KEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSA 298

Query: 285 QNFT----AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQ 340
           Q +                 + Q  +APLM++LIG+P P+N++ ++P+G+LN +  ++ +
Sbjct: 299 QQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAE 358

Query: 341 VLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEAL 400
            +  NA+Q+L Q ++ + + ++  L  L   F+ L  ++  +  +  +  + +E+++E +
Sbjct: 359 SMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVV 418

Query: 401 KVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWF-YLLLVRLARESNHPKSERKGYL 459
            +  ++  LA   + YYH Y  L L +     ++ W  Y  L+ +   SN PK  RK   
Sbjct: 419 SLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGK 478

Query: 460 TWTTLMM---CLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAER-PCQDRD-LMCQ 514
               L++      G+++   +++Q  P     Y LLP  I    L E    QD    +  
Sbjct: 479 KPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVESLLT 538

Query: 515 FPVLHLVG----IVMPGVLLILMAFHNSHIGLLYLPIVCL-NNRRAFFRPSLKLIFWLAL 569
           FP  H V       +   +L+L  F+   +    +         + + R  +  + W   
Sbjct: 539 FPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITFLSWAFF 598

Query: 570 VFLLSGILLVKQSASLHFITDTIGVYIGNSHVVYFSMI------LSIIRPLILGHQHSTR 623
             LL+   L+        ++  +G       +    +       + +++  +L       
Sbjct: 599 SLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQML 658

Query: 624 VWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELII 683
             +++M  +  T + + + +    +        W+ L  + L  P   +  L +RL  I+
Sbjct: 659 STVLSMYVVYSTHHSLLKKE---GLPLMNQIVSWATL-ASSLVAPLLSSTALSQRLASIL 714

Query: 684 FNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANL---KDAIANQQQNNQGLE 740
            ++++ +++L+T   +LF  ++     + +++ +E+     +   +   + Q   +  + 
Sbjct: 715 LSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIA 774

Query: 741 ESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTFKPMTSRLFFPQFHLHM 800
           + R   P+          R A  ++ +L  +FFGTG+     +F   +   F   F   M
Sbjct: 775 QFRQLCPD--------DIRRAFFLVFFLLTAFFGTGNIASINSFDLASVYCFLTVFSPFM 826

Query: 801 LVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYFCYFVINRGSLE 860
           + A ++ KI IP ++VM +  A+    + + + +F+ + +++D M+L+F + V + GS  
Sbjct: 827 MGALMMWKILIPFVLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFFLVKDSGSWL 886

Query: 861 KVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKK 895
            +  S+   ++     I L+  + +A+  L  TKK
Sbjct: 887 DIGTSISHYVIVMSMTIFLVFLNGLAQ--LLTTKK 919
>ref|NP_036459.1| (NM_012327) phosphatidylinositol glycan, class N; endoplasmic
           reticulum membrane protein [Homo sapiens]
 gb|AAD11432.1| (AF109219) Mcd4p homolog [Homo sapiens]
          Length = 931

 Score =  981 bits (2511), Expect = 0.0
 Identities = 227/937 (24%), Positives = 427/937 (45%), Gaps = 62/937 (6%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           ++    L++H +   SI  IYF S ++  + P  T     L PPA RLV+FV DGLRA +
Sbjct: 3   LFFTLGLLIHFVFFASIFDIYFTSPLVHGMTPQFT----PLPPPARRLVLFVADGLRADA 58

Query: 61  VL---ADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW-- 114
           +     +  S  P +R + + +   GIS    PT +RPGH+A+  GF ED +A    W  
Sbjct: 59  LYELDENGNSRAPFIRNIIMHEGSWGISHTRVPTESRPGHVALIAGFYEDVSAVAKGWKE 118

Query: 115 NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFAR---SDISDRLRLDQWT 171
           NP  FDS+FN S+    W   ++  +F    +G     +   A+       D  +LD W 
Sbjct: 119 NPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDFGAQDATKLDTWV 178

Query: 172 FDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGI 228
           FD V++F  + +N Q L    +   ++FF++L  ID   H H P+S +++  +     G+
Sbjct: 179 FDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRDYKHNIKKVDDGV 238

Query: 229 RQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPG 284
           ++   +F   + ND +T ++ T+D+G++    HG G      TP + WGAG+K       
Sbjct: 239 KEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTWGAGIKYPQRVSA 298

Query: 285 QNFT----AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQ 340
           Q F                 + Q  +APLM++LIG+P P+N++ ++P+ +LN +  ++ +
Sbjct: 299 QQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPVDYLNNTDLFKAE 358

Query: 341 VLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEAL 400
            +  NA+Q+L Q ++ + + ++  L  L   F+ L  ++  N  +  +  +   +++E +
Sbjct: 359 SMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKARSYIKHRKFDEVV 418

Query: 401 KVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWF-YLLLVRLARESNHPKSERKGYL 459
            +  ++  LA + + YYH Y    L V     ++ W  Y  L+ +   SN  K   K   
Sbjct: 419 SLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSHSNLIKGVSKEVK 478

Query: 460 TWTTLMMC---LGGLVLLELMILQRVPHLTAFYLLLPFGILILALAE-RPCQDRDL-MCQ 514
             + L+ C     G+++   +++Q  P     Y LLP  I    L E +  QD  + +  
Sbjct: 479 KPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREFQVIQDLVVSVLT 538

Query: 515 FPVLHLVG----IVMPGVLLILMAFHNSHIGLLYLPIVCL-NNRRAFFRPSLKLIFWLAL 569
           +P+ H VG      +   +L+L  F+   +              R + R  +  + W   
Sbjct: 539 YPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWTRAKMTSLSWTFF 598

Query: 570 VFLLSGILLVKQSASLHFITDTIGVYIGNSHVVYFSMILSIIRPLILGHQHSTRVWIVNM 629
             LL+   L+     +      I + +G   +V    +  +   +           +V++
Sbjct: 599 SLLLAVFPLMP----VVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRKDSFIKEELLVHL 654

Query: 630 AALLVTAYGIYQWDAD-------QPVCTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELI 682
             +L T   +Y   +        Q +        W+ L  + L +P   +  L +RL  I
Sbjct: 655 LQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATL-ASSLVVPLLSSPVLFQRLFSI 713

Query: 683 IFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQQNNQGLEES 742
           + ++++ +++L+T   +LF  ++     + + + +E+      +  +  +Q+       S
Sbjct: 714 LLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQ----QSGVCCKQKLT-----S 764

Query: 743 RNESPNNPLEHVRQSY----RYAALILLYLYISFFGTGHWFFNFTFKPMTSRLFFPQFHL 798
              S N  +   RQ Y    R A  ++ +L  +FFGTG+     +F   +   F   F  
Sbjct: 765 IQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDLASVYCFLTVFSP 824

Query: 799 HMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYFCYFVINRGS 858
            M+ A ++ KI IP ++VM +  A+    + + +S+F+ + +++D M+L+F + V + GS
Sbjct: 825 FMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMALHFFFLVKDYGS 884

Query: 859 LEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKK 895
              +  S+   ++     I L+  + +A+  L  TKK
Sbjct: 885 WLDIGTSISHYVIVMSMTIFLVFLNGLAQ--LLTTKK 919
>gb|AAF54657.1| (AE003692) CG6790 gene product [Drosophila melanogaster]
 gb|AAL28155.1| (AY060607) GH02677p [Drosophila melanogaster]
          Length = 858

 Score =  871 bits (2228), Expect = 0.0
 Identities = 339/894 (37%), Positives = 513/894 (56%), Gaps = 74/894 (8%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           +W  + ++VHLLLL  I+ I++QS  LS LEP  TL ++G+ P ADRLVVF+++GLRA +
Sbjct: 3   LWKSKVVLVHLLLLICIMRIFYQSGPLSQLEPQKTLLDMGVPPAADRLVVFLLEGLRADT 62

Query: 61  VLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLTWNPSTFD 120
           + +D+CS    +R++ + Q LVGIS+   PT+TR   +A+F GFN  P+   T   S FD
Sbjct: 63  LFSDNCSGAVYIRDIILRQGLVGISKTSVPTLTRSAEVALFAGFNPMPSILPT---SNFD 119

Query: 121 SVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMT 180
           ++FNR                T     GA LRF     S +SD           +R  +T
Sbjct: 120 TIFNR----------------TLAFDKGAFLRF-----SHLSD-----------LRRRLT 147

Query: 181 NEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFN 240
               ++ L  A  ++  V LA++  A     P  + F+ KL+ TQR IR  YEL E+ FN
Sbjct: 148 KRACLEKLWYANKLVMLVNLAEVGGAS----PLDIGFQMKLHNTQRNIRDAYELIEATFN 203

Query: 241 DSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILP 297
           DS+TAYL T+ +G++    HGGG +   E PF+LWGAGVK    N   +F    NG  + 
Sbjct: 204 DSKTAYLYTSAHGLTYFGSHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLN-NGVGMQ 262

Query: 298 LYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARILI 357
           L++L+QIQLAPLMSALIGLPPP+NN+A++P G++  S +Y  + +HLNA+QLL QA+ +I
Sbjct: 263 LHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLTQAKAII 322

Query: 358 KRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYY 417
           + HE G+ +  LPK + L   +I  Y   + +L+      +AL+ S    K+A + +++Y
Sbjct: 323 RLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKSLKFY 382

Query: 418 HGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLELM 477
           H YYH+PL+V T  + L W +  LV+L++    P   R+GYLTW T+ +   GL+L E++
Sbjct: 383 HNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMAPHYMRRGYLTWCTIFLASLGLLLGEMV 442

Query: 478 ILQRVPHLTAFYLLLPFGILILALAERPCQDRDLMCQFPVLHLVGIVMPGVLLILMAFHN 537
            LQ  P +T   L++PFG+  + LA  P Q+   + + P+ HL  IV P  ++I   + N
Sbjct: 443 FLQWAPFMTVICLVVPFGVWCMTLAALP-QNGGWIFE-PLKHLRWIVGPAAVMIASIYCN 500

Query: 538 SHIGLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYIG 597
             + L Y+  V   NRR +  PS K + WLALV LL G L  ++   +   T        
Sbjct: 501 CPLSLAYILCVGFYNRRGWLHPSPKFLAWLALVLLLGGFLWSQKGMQILMTT-------- 552

Query: 598 NSHVVY--FSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAA 655
           N  VV    SM++ I+RP +L   H  +VW++N   L V A GI+  +  +PV  Y++AA
Sbjct: 553 NYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGILFVAAIGIFLKEMGKPVPLYLFAA 612

Query: 656 CWSYLLFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLEL 715
            W+YL++AF S+P S     + RLELI FN+LT+H++L+ S  SLF Q ++ E+ +GLE+
Sbjct: 613 NWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLEV 672

Query: 716 YEESFSYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGT 775
           +E+               ++ + L  S+         H++  YR+A  ILLY Y S FGT
Sbjct: 673 HEKFKE----------ADEDVKILTSSK---------HLQMCYRFAVSILLYFYASLFGT 713

Query: 776 GHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIF 835
           GHW   FT+   ++RLF P     ++   +L+ + IPSI++M+S+ AL SFGR+ +R+IF
Sbjct: 714 GHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVVALSSFGRQQIRTIF 773

Query: 836 ICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGF 889
             L L+ +A+ L+F  FV +         S+   L++ + +IL+L C  I   F
Sbjct: 774 SSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIVTIF 827
>pir||T46311 hypothetical protein DKFZp434H0711.1 - human (fragment)
 emb|CAB70839.1| (AL137607) hypothetical protein [Homo sapiens]
          Length = 825

 Score =  843 bits (2156), Expect = 0.0
 Identities = 188/829 (22%), Positives = 369/829 (43%), Gaps = 55/829 (6%)

Query: 106 EDPAATL-TW--NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFAR---S 159
           ED +A    W  NP  FDS+FN S+    W   ++  +F    +G     +   A+    
Sbjct: 1   EDVSAVAKGWKENPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAKREDF 60

Query: 160 DISDRLRLDQWTFDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLN 216
              D  +LD W FD V++F  + +N Q L    +   ++FF++L  ID   H H P+S +
Sbjct: 61  GAQDATKLDTWVFDNVKDFFHHARNNQSLFSKINEEKIVFFLHLLGIDTNGHAHRPSSRD 120

Query: 217 FREKLNYTQRGIRQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILW 272
           ++  +     G+++   +F   + ND +T ++ T+D+G++    HG G      TP + W
Sbjct: 121 YKHNIKKVDDGVKEIVSMFNHFYGNDGKTTFIFTSDHGMTDWGSHGAGHPSETLTPLVTW 180

Query: 273 GAGVKRSAPNPGQNFT----AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPL 328
           GAG+K       Q F                 + Q  +APLM++LIG+P P+N++ ++P+
Sbjct: 181 GAGIKYPQRVSAQQFDDAFLKEWRLENWKRLDVNQADIAPLMTSLIGVPFPLNSVGILPV 240

Query: 329 GFLNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIK 388
            +LN +  ++ + +  NA+Q+L Q ++ + + ++  L  L   F+ L  ++  N  +  +
Sbjct: 241 DYLNNTDLFKAESMFTNAVQILEQFKVKMTQKKEVTLPFLFTPFKLLSDSKQFNILRKAR 300

Query: 389 YLVAKEQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWF-YLLLVRLARE 447
             +   +++E + +  ++  LA + + YYH Y    L V     ++ W  Y  L+ +   
Sbjct: 301 SYIKHRKFDEVVSLCKELIHLALKGLSYYHTYDRFFLGVNVVIGFVGWISYASLLIIKSH 360

Query: 448 SNHPKSERKGYLTWTTLMMC---LGGLVLLELMILQRVPHLTAFYLLLPFGILILALAE- 503
           SN  K   K     + L+ C     G+++   +++Q  P     Y LLP  I    L E 
Sbjct: 361 SNLIKGVSKEVKKPSHLLPCSFVAIGILVAFFLLIQACPWTYYVYGLLPLPIWYAVLREF 420

Query: 504 RPCQDRDL-MCQFPVLHLVG----IVMPGVLLILMAFHNSHIGLLYLPIVCL-NNRRAFF 557
           +  QD  + +  +P+ H VG      +   +L+L  F+   +              R + 
Sbjct: 421 QVIQDLVVSVLTYPLSHFVGYLLAFTLGIEVLVLSFFYRYMLTAGLTAFAAWPFLTRLWT 480

Query: 558 RPSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYIGNSHVVYFSMILSIIRPLILG 617
           R  +  + W     LL+   L+     +      I + +G   +V    +  +   +   
Sbjct: 481 RAKMTSLSWTFFSLLLAVFPLMP----VVGRKPDISLVMGAGLLVLLLSLCVVTSLMKRK 536

Query: 618 HQHSTRVWIVNMAALLVTAYGIYQWDAD-------QPVCTYVYAACWSYLLFAFLSIPYS 670
                   +V++  +L T   +Y   +        Q +        W+ L  + L +P  
Sbjct: 537 DSFIKEELLVHLLQVLSTVLSMYVVYSTQSSLLRKQGLPLMNQIISWATL-ASSLVVPLL 595

Query: 671 GTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIA 730
            +  L +RL  I+ ++++ +++L+T   +LF  ++     + + + +E+      +  + 
Sbjct: 596 SSPVLFQRLFSILLSLMSTYLLLSTGYEALFPLVLSCLMFVWINIEQETLQ----QSGVC 651

Query: 731 NQQQNNQGLEESRNESPNNPLEHVRQSY----RYAALILLYLYISFFGTGHWFFNFTFKP 786
            +Q+       S   S N  +   RQ Y    R A  ++ +L  +FFGTG+     +F  
Sbjct: 652 CKQKLT-----SIQFSYNTDITQFRQLYLDDIRRAFFLVFFLVTAFFGTGNIASINSFDL 706

Query: 787 MTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMS 846
            +   F   F   M+ A ++ KI IP ++VM +  A+    + + +S+F+ + +++D M+
Sbjct: 707 ASVYCFLTVFSPFMMGALMMWKILIPFVLVMCAFEAVQLTTQLSSKSLFLIVLVISDIMA 766

Query: 847 LYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLANTKK 895
           L+F + V + GS   +  S+   ++     I L+  + +A+  L  TKK
Sbjct: 767 LHFFFLVKDYGSWLDIGTSISHYVIVMSMTIFLVFLNGLAQ--LLTTKK 813
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  836 bits (2138), Expect = 0.0
 Identities = 186/806 (23%), Positives = 361/806 (44%), Gaps = 56/806 (6%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           ++    L++H +   SI  IYF S ++  + P  T     L PPA RLV+FV DGLRA +
Sbjct: 3   LFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFT----PLPPPAKRLVLFVADGLRADT 58

Query: 61  VL---ADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW-- 114
           +     D  S  P +R + + +   G+S    PT +RPGH+A+  GF ED +A    W  
Sbjct: 59  LYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKE 118

Query: 115 NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFAR---SDISDRLRLDQWT 171
           NP  FDS+FN S+    W   ++  +F    +G     +   A+       D  +LD W 
Sbjct: 119 NPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWV 178

Query: 172 FDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGI 228
           FDKV++F    +N Q L    +   V+FF++L  +D   H H P+S  +++ +     G+
Sbjct: 179 FDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDDGV 238

Query: 229 RQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPG 284
           ++   +F+  + +D +TA++ T+D+G++    HG G      TPF+ WGAG+K       
Sbjct: 239 KEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSA 298

Query: 285 QNFT----AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQ 340
           Q +                 + Q  +APLM++LIG+P P+N++ ++P+G+LN +  ++ +
Sbjct: 299 QQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAE 358

Query: 341 VLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEAL 400
            +  NA+Q+L Q ++ + + ++  L  L   F+ L  ++  +  +  +  + +E+++E +
Sbjct: 359 SMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVV 418

Query: 401 KVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWF-YLLLVRLARESNHPKSERKGYL 459
            +  ++  LA   + YYH Y  L L +     ++ W  Y  L+ +   SN PK  RK   
Sbjct: 419 SLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGK 478

Query: 460 TWTTLMM---CLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAER-PCQDRD-LMCQ 514
               L++      G+++   +++Q  P     Y LLP  I    L E    QD    +  
Sbjct: 479 KPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVESLLT 538

Query: 515 FPVLHLVG----IVMPGVLLILMAFHNSHIGLLYLPIVCL-NNRRAFFRPSLKLIFWLAL 569
           FP  H V       +   +L+L  F+   +    +         + + R  +  + W   
Sbjct: 539 FPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITFLSWAFF 598

Query: 570 VFLLSGILLVKQSASLHFITDTIGVYIGNSHVVYFSMI------LSIIRPLILGHQHSTR 623
             LL+   L+        ++  +G       +    +       + +++  +L       
Sbjct: 599 SLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQML 658

Query: 624 VWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELII 683
             +++M  +  T + + + +    +        W+ L  + L  P   +  L +RL  I+
Sbjct: 659 STVLSMYVVYSTHHSLLKKE---GLPLMNQIVSWATL-ASSLVAPLLSSTALSQRLASIL 714

Query: 684 FNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANL---KDAIANQQQNNQGLE 740
            ++++ +++L+T   +LF  ++     + +++ +E+     +   +   + Q   +  + 
Sbjct: 715 LSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIA 774

Query: 741 ESRNESPNNPLEHVRQSYRYAALILL 766
           + R   P+          R A  +  
Sbjct: 775 QFRQLCPD--------DIRRAFFLFF 792
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  833 bits (2130), Expect = 0.0
 Identities = 208/937 (22%), Positives = 355/937 (37%), Gaps = 91/937 (9%)

Query: 6   ALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLADH 65
            ++ HL  L SI  IYF S ++  + P  +       PPA RL + V DGLRA +     
Sbjct: 13  GVLFHLFYLWSIFDIYFISPLVHGMSPYQS----TPTPPAKRLFLIVGDGLRADTTFDKV 68

Query: 66  CSAV--------PDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAAT-LTW-- 114
              V        P +R L +  A  GIS    PT +RPGH+A+  GF ED +A    W  
Sbjct: 69  THPVSGKTEFLAPFIRSLVMNNATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKS 128

Query: 115 NPSTFDSVFNRSRNAIGWMQAEVAKVF-------THLPTGGAPLRFETFARSDISDRLRL 167
           NP  FDS FN+S +   +   ++  +F         + T      FE F +S I     L
Sbjct: 129 NPVNFDSFFNQSTHTYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSI----EL 184

Query: 168 DQWTFDKVRNFMTNEQNVQPLRDA---TSVIFFVYLADIDLAEHVHMPNSLNFREKLNYT 224
           D + F  +     N      L         +FF++L   D A H + P S  + + + Y 
Sbjct: 185 DAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVKYI 244

Query: 225 QRGIRQTYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAP 281
              I    +     F D +TA++ TAD+G+S    HG G      TP + WGAG+ +   
Sbjct: 245 DDQIPILIDKVNKFFADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNKPVH 304

Query: 282 NP---GQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYE 338
           NP     N+T       +    ++Q  +A LMS LIG+  P N++  +P+ +++     +
Sbjct: 305 NPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKESDK 364

Query: 339 LQVLHLNAMQLLAQARILI-KRHEDGILYLLLPKF-ESLGSAEIENYPQIIKYLVAKEQY 396
           L  L+ NA  +L Q  +   +  +    Y    KF E   S  +E    +I+ +   E Y
Sbjct: 365 LAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEIETLIQRISEGENY 424

Query: 397 --EEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSE 454
             +EA+ ++ ++ ++  E + Y   Y    +    T  ++ W +   +   +        
Sbjct: 425 LEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVGWIFFSFIIFLKSFILENVI 484

Query: 455 RKGYLTW-TTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDRDLMC 513
                +  +  +    G++L  ++  Q  P     YLL P          R       + 
Sbjct: 485 DDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFWSYIFTNR------SVL 538

Query: 514 QFPVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFFRP--SLKLIFWLALVF 571
           +  +        P   +++     S I +    +    +R  F      L    ++  V 
Sbjct: 539 RSGIKEFFKGTSPWKRVLITI---SIISVYEGIVYGFFHRWTFTLITNILAFYPFICGVR 595

Query: 572 LLSG-ILLVKQSASLHFITDTIGVYIGNSHVVYFSMILSIIRPL-ILGHQHSTRVWIVNM 629
            LS  IL +  S  L   T    V I + + ++ + +L I+     L   HS        
Sbjct: 596 ELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSRINSYTRA 655

Query: 630 A----ALLVTAYGIYQW------DADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLRR-- 677
                  LV A               Q +      A W     +   +P    +      
Sbjct: 656 IFAIQISLVAAMLAVTHRSVISLQLRQGLPRESQVAGWIIFFVSLFVMPILHYRKPNNDY 715

Query: 678 --RLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQQN 735
             RL +I        I+LT S  SLF  +  +  V  +E+  +       KD        
Sbjct: 716 KVRLLIIYLTFAPSFIILTISFESLFYFLFTSYMVQWIEIENKIKEMKTQKD-------- 767

Query: 736 NQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTFKPMTSRLFFPQ 795
                           E+  Q  R + +    L ++FFGTG+     +F   +     P 
Sbjct: 768 ----------------ENWLQVLRVSVIGFFLLQVAFFGTGNVASISSFSLESVCRLLPI 811

Query: 796 FHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYFCYFVIN 855
           F   ++ A ++LK+ IP  ++ + +  L         +I   +  M+D +SL F Y +  
Sbjct: 812 FDPFLMGALLMLKLIIPYGLLSTCLGILNLKLNFKDYTISSLIISMSDILSLNFFYLLRT 871

Query: 856 RGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLAN 892
            GS   +  ++    ++ +  + +L+   +    L N
Sbjct: 872 EGSWLDIGITISNYCLAILSSLFMLILEVLGHVLLKN 908
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  830 bits (2122), Expect = 0.0
 Identities = 189/812 (23%), Positives = 366/812 (44%), Gaps = 56/812 (6%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           ++    L++H +   SI  IYF S ++  + P  T     L PPA RLV+FV DGLRA +
Sbjct: 3   LFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFT----PLPPPAKRLVLFVADGLRADT 58

Query: 61  VL---ADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW-- 114
           +     D  S  P +R + + +   G+S    PT +RPGH+A+  GF ED +A    W  
Sbjct: 59  LYELDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKE 118

Query: 115 NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFAR---SDISDRLRLDQWT 171
           NP  FDS+FN S+    W   ++  +F    +G     +   A+       D  +LD W 
Sbjct: 119 NPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWV 178

Query: 172 FDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGI 228
           FDKV++F    +N Q L    +   V+FF++L  ID   H H P+S  +++ +     G+
Sbjct: 179 FDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGV 238

Query: 229 RQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPG 284
           ++   +F+  + +D +TA++ T+D+G++    HG G      TPF+ WGAG+K       
Sbjct: 239 KEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSA 298

Query: 285 QNFT----AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQ 340
           Q +                 + Q  +APLM++LIG+P P+N++ ++P+G+LN +  ++ +
Sbjct: 299 QQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAE 358

Query: 341 VLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEAL 400
            +  NA+Q+L Q ++ + + ++  L  L   F+ L  ++  +  +  +  + +E+++E +
Sbjct: 359 SMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFDEVV 418

Query: 401 KVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWF-YLLLVRLARESNHPKSERKGYL 459
            +  ++  LA   + YYH Y  L L +     ++ W  Y  L+ +   SN PK  RK   
Sbjct: 419 SLCEELIDLALRGLSYYHTYDRLFLGINVAVGFVGWMSYTSLLIIKSHSNIPKGTRKEGK 478

Query: 460 TWTTLMM---CLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAER-PCQDRD-LMCQ 514
               L++      G+++   +++Q  P     Y LLP  I    L E    QD    +  
Sbjct: 479 KPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPIWYAVLREHEVIQDLVESLLT 538

Query: 515 FPVLHLVG----IVMPGVLLILMAFHNSHIGLLYLPIVCL-NNRRAFFRPSLKLIFWLAL 569
           FP  H V       +   +L+L  F+   +    +         + + R  +  + W   
Sbjct: 539 FPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGWPFLTQLWTRAKITFLSWAFF 598

Query: 570 VFLLSGILLVKQSASLHFITDTIGVYIGNSHVVYFSMI------LSIIRPLILGHQHSTR 623
             LL+   L+        ++  +G       +    +       + +++  +L       
Sbjct: 599 SLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQML 658

Query: 624 VWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELII 683
             +++M  +  T + + + +    +        W+ L  + L  P   +  L +RL  I+
Sbjct: 659 STVLSMYVVYSTHHSLLKKE---GLPLMNQIVSWATL-ASSLVAPLLSSTALSQRLASIL 714

Query: 684 FNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYANL---KDAIANQQQNNQGLE 740
            ++++ +++L+T   +LF  ++     + +++ +E+     +   +   + Q   +  + 
Sbjct: 715 LSLMSTYLLLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIA 774

Query: 741 ESRNESPNNPLEHVRQSYRYAALILLYLYISF 772
           + R   P+          R A  ++L ++  F
Sbjct: 775 QFRQLCPD--------DIRRAFFLILLIFPVF 798
>pir||T40715 hypothetical protein SPBC839.08c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA17011.1| (AL021816) hypothetical protein [Schizosaccharomyces pombe]
 emb|CAB46701.1| (AL096796) hypothetical protein [Schizosaccharomyces pombe]
          Length = 935

 Score =  811 bits (2074), Expect = 0.0
 Identities = 200/949 (21%), Positives = 371/949 (39%), Gaps = 90/949 (9%)

Query: 4   IQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLA 63
           +  ++ H++ L SI  IYF + ++  ++  S       E PA RL + V DGLR   +L 
Sbjct: 7   LLGILFHVVFLKSIFDIYFVTPLIHGMKQYS-----AGEAPAKRLFLIVGDGLRPDKLLQ 61

Query: 64  DHCSAV---------PDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAAT-LT 113
            H   V         P LR +       G+S    PT +RPGH+A+  GF ED +A    
Sbjct: 62  PHSEKVIGEEQTYAAPFLRSIIQNNGTFGVSHTRVPTESRPGHVALIAGFYEDVSAVTKG 121

Query: 114 W--NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARS-----DISDRLR 166
           W  NP  FDSVFN+SR+   +   ++  +F+   +   P R +TF  S       S+ + 
Sbjct: 122 WKKNPVNFDSVFNQSRHTYSFGSEDILPMFSEGASD--PSRVDTFMYSSELEDFSSNGIV 179

Query: 167 LDQWTFDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNY 223
           LD+W FD++   +      + L        ++FF++L  ID   H   P+S+ + E + Y
Sbjct: 180 LDEWVFDRLDELLAQSLEDKELWDMLHRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQY 239

Query: 224 TQRGIRQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRS 279
               I++  +   + + ND  ++++ TAD+G+S    HG G      TP I WGAG++  
Sbjct: 240 IDGKIQELVDKMNNYYNNDGASSWVFTADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSP 299

Query: 280 APNPG---QNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQ 336
                     ++   N   +    ++Q  +A LMS L+GL  P+N++  +PL +L+ S +
Sbjct: 300 THEKNYGHDEYSLPWNLTEIKRIDIQQADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSR 359

Query: 337 YELQVLHLNAMQLLAQARIL-IKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQ 395
            + +V  +NA+++  Q  +    + +  I +       +    +   Y  +I  + + E 
Sbjct: 360 RKAEVALMNALEIGEQYNLKSASKDQTSIFFRPYSPLRNYTEVQASFYNSVIADIESGE- 418

Query: 396 YEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSER 455
           YE A++     ++     + Y   Y  L L       YL W   ++  +   +  P    
Sbjct: 419 YEIAIEHCFHFSQTVLSGLRYLQRYDWLLLRSIVFFGYLSWIGYVICFVFSLNIEP---S 475

Query: 456 KGYLTWTTLMMCL---GGLVLLE-LMILQRVPHLTAFYLLLPFGILILALAERPCQDRDL 511
              +   +++  +      +L+     +Q  P     Y L P   L L  +  P      
Sbjct: 476 SKIVKPVSVVKRVAFNIPFLLICIFFYIQSSPPFYYGYALFPTIFLQLIHSIFPNTKLGF 535

Query: 512 M-CQFPVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAF-------------F 557
                      G  +  +L I +      + LL   +    +R  F              
Sbjct: 536 KNFLTVAKQKHGFSLLKILFISL----CILCLLQFIVYSYFHREGFSVILMGLAAWPWLL 591

Query: 558 RPSLKL------IFWLALVFLLSGILLVK--QSASLHFITDTIGVYIGNSH--VVYFSMI 607
                       + W  L  LL    ++   +  SL FI              ++Y    
Sbjct: 592 HADYAFSHKTISVSWSVLTSLLCFFTILPVNKKESLLFIFAGGFAMSVAGVFYILYRRNQ 651

Query: 608 LSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYAACWSYLLFAFLSI 667
                  +   Q   +V I+ MA + VT         +  +   +    +   + +++  
Sbjct: 652 AFQYSSTVTNKQLVLQVLII-MATVPVTLKIADSLQRNIAIPPILRLVAFGLFITSYIIP 710

Query: 668 PY---SGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESFSYAN 724
            +   S       RL ++         ML+ S  +LF  ++     L +EL  E   Y  
Sbjct: 711 SHHIRSCKHYFLDRLAILFLTFSPTMCMLSISFEALFYVVLFITLGLWMELETELQKYT- 769

Query: 725 LKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFGTGHWFFNFTF 784
                   +Q +      ++   +  L H+    R +    +++ ++FFGTG+     TF
Sbjct: 770 --------EQLHPEYSRKKDAKFHLSLSHI----RISLFFYIFINVAFFGTGNVASLSTF 817

Query: 785 KPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSI-YALVSFGRKNVRSIFICLFLMND 843
              + + F P F+     A ++  I +P I + ++        G     + F+ +  M D
Sbjct: 818 ALDSVKRFIPVFNPVTQGALLMYTILVPFIALSAAFGIMNKRLGGIQQVTFFLAVG-MAD 876

Query: 844 AMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGFLAN 892
            +++ F Y V + GS + +  S+    +S+  I+ +      +     N
Sbjct: 877 IVTINFFYLVKDEGSWKDIGVSISHFCISNFLILFITALEHASAILCKN 925
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  708 bits (1808), Expect = 0.0
 Identities = 259/732 (35%), Positives = 377/732 (51%), Gaps = 47/732 (6%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           MW   ALVVH+LLLGSI  IYF+S +++ L P   L   GLEPPA+RLV+ V DG RA S
Sbjct: 1   MWIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADS 60

Query: 61  VLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW--NPS 117
              ++C  VP+LR++F+ + +VG+SR   PT TRPGHI +  G  EDP+A L  W  NP 
Sbjct: 61  FFEENCRYVPNLRKIFLREGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPI 120

Query: 118 TFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGA-PLRF--ETFARSDISDRLRLDQWTFDK 174
            FD+VFNRS     W   +V  VF+H+  GG   LRF       S   D    D+W F +
Sbjct: 121 DFDTVFNRSSQTYAWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDEWVFKR 180

Query: 175 VRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYEL 234
           V+  +  +Q  + L+ A +V+FF++L  +D A HVH P +  FR  L  T++G+   Y+ 
Sbjct: 181 VKLLL--QQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAIYQE 238

Query: 235 FESVFNDSRTAYLMTADYGISLHGGGGERGVETPFILWGAGVKRSAPNP-GQNFTAGENG 293
           FE VF D RTAYL+TAD+G++                  +G  R+ P P G+ F     G
Sbjct: 239 FERVFPDKRTAYLLTADHGMT-----------------DSGASRAVPKPGGRTFMPNNEG 281

Query: 294 PILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQA 353
           P +PL++LEQ QL PLMSAL+GL PPMNN   +PLG+LN S +YE    H+NA+QLL Q 
Sbjct: 282 PAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKEYEAMAAHVNALQLLEQY 341

Query: 354 RILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQEC 413
             L K+H+ G    +L +++ L +  I+ Y   I  L  K +Y   +  S  I   A E 
Sbjct: 342 VALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKREYSLCIDKSQVIMSQALEG 401

Query: 414 MEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKS---ERKGYLTWTTLMMCLGG 470
           ++YYHGYY   LL++TT+++L W + +   L+R          ER   +   +++  +  
Sbjct: 402 IDYYHGYYRRVLLLSTTSTFLGWMFYIYRLLSRNRASKVELVLERSNKIVRVSIVSSV-- 459

Query: 471 LVLLELMILQRVPHLTAFYLLLPFGILILAL-------AERPCQDRDL-MCQFPVLHLVG 522
           +VL+  ++ Q  P   +FYLLLP+ + + AL       +  P     +   Q  +  LV 
Sbjct: 460 IVLIICLLSQGTPLDISFYLLLPYFVWLKALQPWNINFSSSPASAYSVPALQTSMWQLVL 519

Query: 523 IVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSGILLVKQS 582
           ++    L++   F    I L +    C N+   F   S     WLALV +LS   L+  S
Sbjct: 520 LIACAELMVFTFFERRLIALCFCVFACYNSWENFQWKSRDFFSWLALVLILSCFPLLPLS 579

Query: 583 ASLHFITDTIGVYIGNSHVVYFSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQW 642
                     G  +G   +V F+      +  +    H+      N   LL T    Y  
Sbjct: 580 VGYQN-----GYLLGAGVIVIFTNSFWNSKSRLCYRNHTK---YSNALILLQTILCAYLH 631

Query: 643 DADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFV 702
                +   +  A W YL++AF SI  S    L  RL  I FN+ +++  L TS  ++FV
Sbjct: 632 SNGINIPIPLKLASWLYLVYAFASILLSKESRLDLRLAQIGFNLGSLYATLCTSYEAVFV 691

Query: 703 QIMVTEFVLGLE 714
           Q++  E  + L 
Sbjct: 692 QLLTIELNISLR 703
 Score =  167 bits (420), Expect = 8e-40
 Identities = 46/136 (33%), Positives = 75/136 (54%)

Query: 755 RQSYRYAALILLYLYISFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSI 814
           R   R A  +LLY + S FG+G+     +F P  +R +   F   +++  +LLK+ +P +
Sbjct: 711 RSVLRLAFTLLLYTFFSLFGSGNIASISSFDPNIARCYLSHFAPFVIMGLVLLKLLVPVV 770

Query: 815 IVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHV 874
           ++MS IYA   F R++   IFICL L+ D M L F + V N+GS   +  S+   ++  V
Sbjct: 771 LIMSVIYANSEFVRQHEEQIFICLLLICDVMGLNFLFLVRNQGSWLDIGTSISHFVIMEV 830

Query: 875 FIILLLVCSWIAKGFL 890
             +++LV  + AK  L
Sbjct: 831 TTLVMLVIFYTAKQLL 846
>ref|XP_082200.1| (XM_082200) CG6790 [Drosophila melanogaster]
          Length = 656

 Score =  677 bits (1730), Expect = 0.0
 Identities = 244/655 (37%), Positives = 374/655 (56%), Gaps = 37/655 (5%)

Query: 237 SVFNDSRTAYLMTADYGISLHGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPIL 296
             F    T  L++       HGGG +   E PF+LWGAGVK    N   +F    NG  +
Sbjct: 6   HTFIHQHTVLLISG-----SHGGGSDEEREAPFLLWGAGVKHVTENITSDFVLN-NGVGM 59

Query: 297 PLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARIL 356
            L++L+QIQLAPLMSALIGLPPP+NN+A++P G++  S +Y  + +HLNA+QLL QA+ +
Sbjct: 60  QLHKLDQIQLAPLMSALIGLPPPVNNLAILPQGYMKVSREYARKSVHLNALQLLTQAKAI 119

Query: 357 IKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEY 416
           I+ HE G+ +  LPK + L   +I  Y   + +L+      +AL+ S    K+A + +++
Sbjct: 120 IRLHERGVFHKWLPKDKDLDLQQIAYYQNQMDHLLDMGWRSKALETSTLAIKVALKSLKF 179

Query: 417 YHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLEL 476
           YH YYH+PL+V T  + L W +  LV+L++    P   R+GYLTW T+ +   GL+L E+
Sbjct: 180 YHNYYHIPLVVTTVLALLGWQFYQLVKLSQNVMAPHYMRRGYLTWCTIFLASLGLLLGEM 239

Query: 477 MILQRVPHLTAFYLLLPFGILILALAERPCQDRDLMCQFPVLHLVGIVMPGVLLILMAFH 536
           + LQ  P +T   L++PFG+  + LA  P Q+   + + P+ HL  IV P  ++I   + 
Sbjct: 240 VFLQWAPFMTVICLVVPFGVWCMTLAALP-QNGGWIFE-PLKHLRWIVGPAAVMIASIYC 297

Query: 537 NSHIGLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSGILLVKQSASLHFITDTIGVYI 596
           N  + L Y+  V   NRR +  PS K + WLALV LL G L  ++   +   T       
Sbjct: 298 NCPLSLAYILCVGFYNRRGWLHPSPKFLAWLALVLLLGGFLWSQKGMQILMTT------- 350

Query: 597 GNSHVVY--FSMILSIIRPLILGHQHSTRVWIVNMAALLVTAYGIYQWDADQPVCTYVYA 654
            N  VV    SM++ I+RP +L   H  +VW++N   L V A GI+  +  +PV  Y++A
Sbjct: 351 -NYRVVLQAISMLVVIVRPCVLNENHKWKVWVINGGILFVAAIGIFLKEMGKPVPLYLFA 409

Query: 655 ACWSYLLFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLE 714
           A W+YL++AF S+P S     + RLELI FN+LT+H++L+ S  SLF Q ++ E+ +GLE
Sbjct: 410 ANWAYLIYAFASVPCSSRTTPQSRLELIRFNLLTLHVLLSDSYVSLFAQGLIIEYQMGLE 469

Query: 715 LYEESFSYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYLYISFFG 774
           ++E+               ++ + L  S+         H++  YR+A  ILLY Y S FG
Sbjct: 470 VHEKFKE----------ADEDVKILTSSK---------HLQMCYRFAVSILLYFYASLFG 510

Query: 775 TGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKNVRSI 834
           TGHW   FT+   ++RLF P     ++   +L+ + IPSI++M+S+ AL SFGR+ +R+I
Sbjct: 511 TGHWVGGFTYLANSARLFLPDSSSGLVPLLVLIHLLIPSIVIMASVVALSSFGRQQIRTI 570

Query: 835 FICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIAKGF 889
           F  L L+ +A+ L+F  FV +         S+   L++ + +IL+L C  I   F
Sbjct: 571 FSSLMLICNAVVLFFVVFVPHNAYWPMAHPSVVHALLAQLTVILILACESIVTIF 625
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  535 bits (1365), Expect = e-150
 Identities = 158/622 (25%), Positives = 263/622 (41%), Gaps = 59/622 (9%)

Query: 4   IQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLA 63
           +  + +H + + SI  IYF++ I+  ++P+        EPPA RLV+ + DGLRA     
Sbjct: 48  VLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS---EPPAKRLVLLISDGLRADKFFE 104

Query: 64  DHCS---AVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAAT-LTW--NPS 117
                    P LR +   Q   G+S A PPT +RPGH+AI  GF EDP+A    W  NP 
Sbjct: 105 PDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPV 164

Query: 118 TFDSVFNRSRNAIGWMQAEVAKVFT----HLPTGGAPLRFETFARSDISDRLRLDQWTFD 173
            FDSVFN+SR+   +   ++  +F     H      P  +E FA     D   LD+W+FD
Sbjct: 165 EFDSVFNQSRHTFAFGSPDIIPIFCSALPHSTWNSYPHEYEDFAT----DASFLDEWSFD 220

Query: 174 KVRNFMTNEQ---NVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQ 230
           +    +        ++ L     ++ F++L   D   H H P S  +   +    +   +
Sbjct: 221 QFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAER 280

Query: 231 TYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPGQNF 287
            Y L E  + D+RT+Y+ TAD+G+S    HG G     +TP + WGAG++   P  G + 
Sbjct: 281 VYHLLEDYYRDNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSH 340

Query: 288 T------AGENGPILP-----------LYQLEQIQLAPLMSALIGLPPPMNNMALMPLGF 330
           +        ++   +P              + Q  +APLMS L+GLP P+N++  +PLG+
Sbjct: 341 SDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGY 400

Query: 331 LNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYL 390
           +  +   E++ +  N  Q+L Q  +L K +      L    F+ L           I  L
Sbjct: 401 MKLNEAEEVEAVVANTKQILNQ--LLRKSYIKSSNSLFFKPFKPLVHHSFS--LSQIDEL 456

Query: 391 VAKEQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLL-LVRLARESN 449
           ++ + YE A+K++  +  L+ E + Y+  Y  L L+   T  Y  W  +L L  L   S+
Sbjct: 457 ISAKSYEAAMKLAVDLRNLSLEGLHYFQTYDWLMLMTVITLGYTGWMIVLALHVLQCYSS 516

Query: 450 HPKSERKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALAERPCQDR 509
                 K       +  CL   +L  L +++  P L   Y+ +   +     +E      
Sbjct: 517 LSGDLSKKEHLSVYISGCLLMAILSVLNLVEHSPPLYHAYIGMTVFLWTQIFSEYRLIRG 576

Query: 510 DLMCQFPVLHLVGIVMPGVLLI-LMAFHNSHIGLLYLPIVCLNNRRAFFRPSLKLIFWLA 568
                                I L+      + ++ L +     R+ +            
Sbjct: 577 LWKYLRER--------RADYFIKLLFAAAVAVVIVELLVHSFTERKLYTW----FFLIAG 624

Query: 569 LV-FLLSGILLVKQSASLHFIT 589
           +V  +L    +  +S    F+ 
Sbjct: 625 VVASILLHFSIPWRSGIPVFVC 646
 Score =  283 bits (719), Expect = 7e-75
 Identities = 55/356 (15%), Positives = 127/356 (35%), Gaps = 58/356 (16%)

Query: 574 SGILLVKQSASLHFITDTIGVYIG---NSHV-VYFSMILSIIRPLILGHQHSTRVWIVNM 629
           +  L  +  +    I            +  + + F+  ++++   +L H  + R      
Sbjct: 560 TVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVVIVELLVHSFTERKLYTWF 619

Query: 630 AALLVTAYGIYQWDA---DQPVCTYVYAACWSYLLFAF----------LSIPYSGTKDLR 676
             +      I    +      +  +V  +CW   +F            L  P+ G  D  
Sbjct: 620 FLIAGVVASILLHFSIPWRSGIPVFVCISCWFLSVFTLMPAEIPDNNNLVSPFLGANDTD 679

Query: 677 ----------------RRLELIIFNMLTVHIMLTTSIGSLFVQIMVTEFVLGLELYEESF 720
                              E  I  + +VH +++    ++F   +    +  +       
Sbjct: 680 IFGWCVICDGVFVDKASNAESRIAFVTSVHKLVSCRYEAVFYSALAVVLMAWILFE---- 735

Query: 721 SYANLKDAIANQQQNNQGLEESRNESPNNPLEHVR----------QSYRYAALILLYLYI 770
                     N   ++  ++ES + S NN  EH+              R   + ++   +
Sbjct: 736 ----------NASHHSSKVKES-SLSENNTEEHITIGSDERYLQLSDVRIPLVFMVLFNV 784

Query: 771 SFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGRKN 830
           +FFGTG++    +F+  +   F   F   ++ A ++ K+FIP ++V+ +  A+    R  
Sbjct: 785 AFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICAFSAITKLVRVP 844

Query: 831 VRSIFICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHVFIILLLVCSWIA 886
               +  + L +D M+++F + V N GS  ++  S+    +    ++ +L+   + 
Sbjct: 845 RLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQVVFVLLLFALT 900
>gb|AAF59557.2| (AC024812) Hypothetical protein Y54E10BR.1 [Caenorhabditis elegans]
          Length = 929

 Score =  529 bits (1351), Expect = e-149
 Identities = 162/617 (26%), Positives = 262/617 (42%), Gaps = 66/617 (10%)

Query: 2   WSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSV 61
           + I ++ VHL+L+ SI  +Y+ S ++  + P     +   E PA R+ +   DGLR  + 
Sbjct: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQ---EAPAKRIFIISADGLRYDT- 60

Query: 62  LADHCSAVPDLRELFV-EQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW--NPS 117
              +    P L  +    + + G+SR+  PT +RPGH+AIF G  ED +A    W  NP 
Sbjct: 61  FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120

Query: 118 TFDSVFNRSRNAIGWMQAEVAKVFTHLPTG---GAPLRFETFARSDISDRLRLDQWTFDK 174
            FDSVFNRS  +  W   ++  +F  LP           E FA  D S+   LD+W F+ 
Sbjct: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASN---LDKWVFEH 177

Query: 175 VRNFMTNEQNVQPLRD---ATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQT 231
             NF+   +  + L D       IFF++L  ID   H + P S  + + +     GI + 
Sbjct: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237

Query: 232 YELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPGQNFT 288
             L ++ F D +TA+L T+D+G++    HG G +  V TPF+ WGAGVK+  P       
Sbjct: 238 QHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPK------ 291

Query: 289 AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTS-VQYELQVLHLNAM 347
                       L QI LAPL+SALIG P P+N+M ++P+  +N+    YE + +  N  
Sbjct: 292 ----------LDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFK 341

Query: 348 QLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIA 407
           QL  Q   L          L   +FE  G   +E+    +  L    ++  A  +    A
Sbjct: 342 QLKEQIIFLKNAKSRR---LWFRQFEKFGDKAMESLRTTLAQLGRDRRFSVATSLFADNA 398

Query: 408 KLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYLTWTTLM-- 465
            L +E + +YH Y    L  A + S++ W     + ++   N    E    L    L   
Sbjct: 399 HLMKEAIVFYHRYDRQMLGAAVSCSFVAWI---ALVVSFLHNSTSKENLSLLVPHHLFII 455

Query: 466 MCLGGLVLLELMILQRVPHLTAFYLLLPFGIL-------------ILALAERP---CQDR 509
                L+      L     +     +    IL             + AL+ +P    +  
Sbjct: 456 PLACSLLFTAYCSLSMTQTIYIILPIYLISILENHSKLTQRIREHVKALSAQPDWLNKVL 515

Query: 510 DL-MCQFPVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFFRPSLKLIF--W 566
            + +   P L  VG  +   + +L     + +  +++ ++ L     +  P +      W
Sbjct: 516 SVEVFVKPFLGFVGFSITICIFVLTFMDRAFLAAVFVLLMALPQF--YSHPIVSYWSKTW 573

Query: 567 LALVFLLSGILLVKQSA 583
           L L  +L     +    
Sbjct: 574 LTLCLVLCIFPFLPAVG 590
 Score =  223 bits (563), Expect = 1e-56
 Identities = 44/225 (19%), Positives = 91/225 (39%), Gaps = 15/225 (6%)

Query: 649 CTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTE 708
            +      W+ +  + ++        L  RL          + +L+ S  SLF+ I +  
Sbjct: 673 PSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVL 732

Query: 709 FVLGLELYEESFSYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYL 768
             L +       S   L     +  + + G             E+V    R   + + ++
Sbjct: 733 LTLFVRFEFGHLSDVELLQLKVDSTKISTG-------------EYVE--LRRTVVCVSFV 777

Query: 769 YISFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGR 828
               FGTG++    +F P T  LF   F    +   ++LK+ IP ++V S+  ++V F +
Sbjct: 778 LCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQ 837

Query: 829 KNVRSIFICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSH 873
           ++++ +     +  D MS+ F + + + GS   +  S+ + +VS 
Sbjct: 838 ESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 882
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  493 bits (1258), Expect = e-138
 Identities = 120/393 (30%), Positives = 204/393 (51%), Gaps = 24/393 (6%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           ++    L++H +   SI  IYF S ++  + P  T     L PPA RLV+FV DGLRA +
Sbjct: 3   LFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFT----PLPPPAKRLVLFVADGLRADT 58

Query: 61  VL---ADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW-- 114
           +     D  S  P +R + + +   G+S    PT +RPGH+A+  GF ED +A    W  
Sbjct: 59  LYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKE 118

Query: 115 NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFAR---SDISDRLRLDQWT 171
           NP  FDS+FN S+    W   ++  +F    +G     +   A+       D  +LD W 
Sbjct: 119 NPVEFDSLFNESKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWV 178

Query: 172 FDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGI 228
           FDKV++F    +N Q L    +   V+FF++L  ID   H H P+S  +++ +     G+
Sbjct: 179 FDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGV 238

Query: 229 RQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPG 284
           ++   +F+  + +D +TA++ T+D+G++    HG G      TPF+ WGAG+K       
Sbjct: 239 KEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSA 298

Query: 285 QNFT----AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQ 340
           Q +                 + Q  +APLM++LIG+P P+N++ ++P+G+LN +  ++ +
Sbjct: 299 QQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFKAE 358

Query: 341 VLHLNAMQLLAQARILIKRHEDGILYLLLPKFE 373
            +  NA+Q+L Q ++ + + ++  L  L   F+
Sbjct: 359 SMFTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>gb|AAF54658.1| (AE003692) CG5342 gene product [Drosophila melanogaster]
          Length = 559

 Score =  478 bits (1220), Expect = e-133
 Identities = 143/613 (23%), Positives = 247/613 (39%), Gaps = 83/613 (13%)

Query: 288 TAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAM 347
            A E G  LPL+ L    L  LMSAL+G+PPP+ +  ++P G LN S++YE   + +NA 
Sbjct: 1   MANEAGLRLPLHVLNTPHLTALMSALLGVPPPVYSRGMLPKGMLNASLRYEANAMLINAK 60

Query: 348 QLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIA 407
           QLLAQAR L + H   +          L    ++N+ +    L  + ++   L  S    
Sbjct: 61  QLLAQARRLRELHPKRMPAFW------LSFQMMDNFVKESLALKKQRRFRALLDYSCNYM 114

Query: 408 KLAQECMEYYHGYYHLPLLVATTASYLVWFYLL---LVRLARESNHPKSERKGYLTWTTL 464
            +  + M+Y+  YY    + A + + + W Y L   L    +  N    E +  ++   L
Sbjct: 115 PVLIKGMDYFKDYYRHVSITAVSFAGIAWIYCLRCHLTVGKKCRNLI--EIQEVISSKRL 172

Query: 465 MMC------LGGLVLLELMILQRVPHLTAFYLLLPFGIL---ILALAERPCQDRDLMCQF 515
           +        L G++++ +M L+R+P +    LL+P       +  L ERP     ++C  
Sbjct: 173 VYARGFHRLLTGVLVIIMM-LERIPLVVQAILLIPSLYWRTTLKILGERP----KMVC-- 225

Query: 516 PVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFFRPSLKLIFWLALVFLLSG 575
               L+   +  ++     F    + + YL     NNR AF R   +   WL L+  L+ 
Sbjct: 226 -RKSLMSTALLALICFGGFFRRYILAVGYLGFASYNNREAFKRRGHQFYLWLLLLLGLTV 284

Query: 576 ILLVKQSASLHFITDTIGVYIGNSHVVYFSMILSIIRPLILGHQHSTRVWIVNMAALLVT 635
           +  + +S          G  +       FS+ L+++RPL  G   +   W+ N+  LL  
Sbjct: 285 VSALPESLG----CSQPGALM-------FSIFLTVLRPLACGVYLNLLTWLSNIPVLLAA 333

Query: 636 AYGIYQWDADQPVCTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTT 695
              I            +Y   W YL   FL       ++L+   E+  F++ T++ +  T
Sbjct: 334 LEYILIGWH----PWIMYLVSWIYL--GFLV--LWQRRNLQAS-EVFFFDLSTLYTLTCT 384

Query: 696 SIGSLFVQIMVTEFVLGLELYEESFSYANLKDAIANQQQNNQGLEESRNESPNNPLEHVR 755
           S  S+ +Q++  E  L L +  +       K A                           
Sbjct: 385 SYESVVIQMLAMELQLALRMKLKRNESIGPKTA--------------------------- 417

Query: 756 QSYRYAALILLYLYISFFGTGHWFFNFTF-KPMTSRLFFPQFHLHMLVAFILLKIFIPSI 814
                A  IL+Y + S F  G +     F   +    F   +        ++LK+ +P +
Sbjct: 418 -----AHYILVYSWYSLFIIGSFPAFDDFLDILHETCF--GYSPLTYGLVMVLKLILPWL 470

Query: 815 IVMSSIYALVSFGRKNVRSIFICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSHV 874
           +V+  +           + IF+ L LMN AMSL   + + N G    +        V HV
Sbjct: 471 LVLCIMAGNYKSLASYEQQIFVRLLLMNSAMSLVLLHGITNVGPWRDILSRFAEFAVVHV 530

Query: 875 FIILLLVCSWIAK 887
           F ++ L+   + +
Sbjct: 531 FPLVWLLLWRLTQ 543
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  441 bits (1125), Expect = e-122
 Identities = 98/607 (16%), Positives = 188/607 (30%), Gaps = 73/607 (12%)

Query: 7   LVVHLLLLGSILSIYFQSTIL---SDLEPLSTLRELG-LEPPADRLVVFVVDGLRAQSVL 62
           L+V + +L  I   +F    L     L+ +S+  E   L P  ++ V+ V+D LR    +
Sbjct: 38  LLVFIAILQFISIAFFTRGFLLSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFAI 97

Query: 63  ADHCSAVPDLRELFVEQALVGISR--------------ACPPTVTRPGHIAIFGGFNEDP 108
             + S              +  S               A PPT T      +  G     
Sbjct: 98  PVNESHSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTF 157

Query: 109 AATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLD 168
               +       +V            A     F    T  A   F  F  +D      L+
Sbjct: 158 IDAGSNFDG---TVIEEDNFLKQLHLANKTVKFAGDDTWMAL--FHPFLSNDSFPLESLN 212

Query: 169 QWTFDKVRN-----FMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNY 223
            W  D V N     F  + Q  +        +   ++  ID   H + P+    REK   
Sbjct: 213 VWDLDTVDNGVMDYFHDHLQQDKE-----WDVMIGHMLGIDHVGHKYGPDHFTMREKQIQ 267

Query: 224 TQRGIRQTYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSA 280
             + I    +       D  T  ++  D+G+     HGG     +E+   L+        
Sbjct: 268 VDQFIDWILKSI-----DDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSKKPDMWR 322

Query: 281 PNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQ 340
                N+     G       + QI L   ++ L+G P P NN+   P+  +  + +   Q
Sbjct: 323 LKETSNYNIDNLGHDY--RSVRQIDLVSSLALLMGQPIPFNNLG-WPIDEIARNDREWSQ 379

Query: 341 VLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEA- 399
            +  +A+  L   +  ++ H      L  P  +++ +    + P+    L    +Y++  
Sbjct: 380 FV-NSAISQLQLYKDTMQIHHGNDEILE-PLAKNISNTPPTSDPEKFVKL--GHKYQKVF 435

Query: 400 LKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARESNHPKSERKGYL 459
           L+   ++        +YY         +AT  + L      LV L   +    S     +
Sbjct: 436 LQTCEEL----WAKFDYYS--------IATGITLLA---TSLVLLISITKLIPSIVVNQM 480

Query: 460 TWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGILILALA-ERPCQDRDLMCQFPVL 518
               +   +  +++  L                        LA          +  F   
Sbjct: 481 VPEFVPGIIIMVLVTNLCF--HGIFYVYQQPSFVDQFWGTLLATAIGIIIGCYITIFDRY 538

Query: 519 HLVGIVMPGVLLILMAFHNSHIGLLYLPIVCL----NNRRAFFRPSLKLIFWLALVFLLS 574
           + + I M     +   +    I ++++ I  L    N+   +    +  +     +  L 
Sbjct: 539 NFIWIAMRLGETLADYWSR--IAVMFMIIHALLFTSNSFTIWEDRIVAFLLSTFGMLTLY 596

Query: 575 GILLVKQ 581
             + + +
Sbjct: 597 EFVFLPK 603
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  404 bits (1028), Expect = e-111
 Identities = 96/649 (14%), Positives = 178/649 (26%), Gaps = 123/649 (18%)

Query: 2   WS-IQALVVHLLLLGSILSIY----FQSTILS--DLEPLSTLRELGL------------- 41
           W  IQA +     +  I + Y    F    L    +   ++L E                
Sbjct: 19  WKYIQACI--FFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCW 76

Query: 42  -EPPADRLVVFVVDGLRAQSVLADHCSA-------VPDLRELFVEQALVGISR-ACPPTV 92
                +R V+ ++D LR   ++  + S         P    +   +        A  PT 
Sbjct: 77  APKIFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTT 136

Query: 93  TRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGA-PL 151
           T      +  G         +       +  +     + W   +   V     T      
Sbjct: 137 TSQRLKGLTTGSLPTFIDLGSNFAG---TNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFH 193

Query: 152 RF------ETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDL 205
            +      +     ++ D   +D      V +++          DA   +   +   +D 
Sbjct: 194 DYLNETLSQPAFSFNVPDLHGVDNKVNQYVFDYIK---------DANFDVLIAHYLGVDH 244

Query: 206 AEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGIS---LHGGGGE 262
             H   P+    R+KLN   R +++  +L      D  T  ++  D+G+     HGG   
Sbjct: 245 VGHRLGPDHPTMRDKLNQMDRCVKEMMDLL-----DDSTLLIVMGDHGMDNKGNHGGDSF 299

Query: 263 RGVETPFILWGAGVKRSAPN-PGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMN 321
             + +   ++           PG+  +A             Q+ L P +S L+G P P  
Sbjct: 300 DEINSVLWMYSKKPTFGYLKQPGKVLSA------------NQVDLVPTLSLLLGNPIPYG 347

Query: 322 NMA-LMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFES-LGSAE 379
           N+  L+P  F     +Y  +   +N  QL            +             L S+ 
Sbjct: 348 NLGTLIPEPFYYYGDEYLSKAQKINIGQL------------NRFFSEYDLDASDFLSSSV 395

Query: 380 IENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFY- 438
            +N    +        Y             A++   Y+   +    L      +L+    
Sbjct: 396 HKNNNSYLDQYFLDFDY-------------ARDAFSYFKAIWAEFSLFPMIIGFLLLIIG 442

Query: 439 -LLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLPFGIL 497
              L  L ++ +                + +  +++L    L   P    FY+LLP    
Sbjct: 443 GFNLALLMQDKSVIFRMSANMAPSVMKCLPVCLILILANNEL-HSPFPAEFYVLLPSFY- 500

Query: 498 ILALAERPCQDRDLMCQFPVLHLVGIVMPGVLLILMAFHNSHIGLLYLPIVCLNNRRAFF 557
              L     Q             V          L  F    I  L++     N+   + 
Sbjct: 501 --ILLNSFNQKLMEYF----KGFVK---------LDYFS-IFITFLHVCSFGSNSFTVWE 544

Query: 558 RPSLKLIFWLALVFLLS-GILLVKQSASLHFITDTIGVYIGNSHVVYFS 605
                 +     + +            S  F   T          V  S
Sbjct: 545 DRLCHFLIITIGLVMFCKCFS----EMSPLFACSTYSALAFILLQVISS 589
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  377 bits (960), Expect = e-103
 Identities = 95/304 (31%), Positives = 153/304 (50%), Gaps = 20/304 (6%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           ++    L++H +   SI  IYF S ++  + P  T     L PPA RLV+FV DGLRA +
Sbjct: 3   LFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFT----PLPPPAKRLVLFVADGLRADT 58

Query: 61  VL---ADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW-- 114
           +     D  S  P +R + + +   G+S    PT +RPGH+A+  GF ED +A    W  
Sbjct: 59  LYELDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKE 118

Query: 115 NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFAR---SDISDRLRLDQWT 171
           NP   DS+FN  +    W   ++  +F    +G     +   A+       D  +LD W 
Sbjct: 119 NPVESDSLFNERKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDTWV 178

Query: 172 FDKVRNFMTNEQNVQPLR---DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGI 228
           FDKV++F    +N Q L    +   V+FF++L  ID   H H P+S  +++ +     G+
Sbjct: 179 FDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDDGV 238

Query: 229 RQTYELFESVF-NDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPG 284
           ++   +F+  + +D +TA++ T+D+G++    HG G      TPF+ WGAG+K       
Sbjct: 239 KEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNVSA 298

Query: 285 QNFT 288
           Q + 
Sbjct: 299 QQYD 302
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  375 bits (955), Expect = e-102
 Identities = 120/364 (32%), Positives = 183/364 (49%), Gaps = 37/364 (10%)

Query: 2   WSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSV 61
           + I ++ VHL+L+ SI  +Y+ S ++  + P     +   E PA R+ +   DGLR  + 
Sbjct: 5   FLIASITVHLVLIYSIFDVYYTSPLVHGIPPQFINSQ---EAPAKRIFIISADGLRYDT- 60

Query: 62  LADHCSAVPDLRELFV-EQALVGISRACPPTVTRPGHIAIFGGFNEDPAATL-TW--NPS 117
              +    P L  +    + + G+SR+  PT +RPGH+AIF G  ED +A    W  NP 
Sbjct: 61  FNKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPV 120

Query: 118 TFDSVFNRSRNAIGWMQAEVAKVFTHLPTG---GAPLRFETFARSDISDRLRLDQWTFDK 174
            FDSVFNRS  +  W   ++  +F  LP           E FA  D S+   LD+W F+ 
Sbjct: 121 QFDSVFNRSSYSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASN---LDKWVFEH 177

Query: 175 VRNFMTNEQNVQPLRD---ATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQT 231
             NF+   +  + L D       IFF++L  ID   H + P S  + + +     GI + 
Sbjct: 178 FENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEKV 237

Query: 232 YELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPGQNFT 288
             L ++ F D +TA+L T+D+G++    HG G +  V TPF+ WGAGVK+  P       
Sbjct: 238 QHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPK------ 291

Query: 289 AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTS-VQYELQVLHLNAM 347
                       L QI LAPL+SALIG P P+N+M ++P+  +N+    YE + +  N  
Sbjct: 292 ----------LDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFK 341

Query: 348 QLLA 351
           Q++ 
Sbjct: 342 QVIN 345
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  348 bits (884), Expect = 3e-94
 Identities = 85/468 (18%), Positives = 154/468 (32%), Gaps = 65/468 (13%)

Query: 2   WSIQALVVHLLLLGSILSIYFQSTILSDLEPLST--LRELGLEPPADRLVVFVVDGLRAQ 59
           ++  +    L +L  I + + +  +L+ +        R+L  + P  +LV  ++D LR+ 
Sbjct: 6   FTCLSCAQLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSD 65

Query: 60  SVLADHCSAVPDLRELFVEQALVGI-SRACPPTVTRPGHIAIFGGFNEDPAATLTWNPST 118
            +     S   ++ +        G  S A PPTVT P   +I  G        L      
Sbjct: 66  FLFDSQISHFNNVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQD 125

Query: 119 FDSVFNRSRNAIGWMQAEVAK------VFTHLPTGGAPLRFETFA----RSDISDRLRLD 168
            DS  N       W+Q  +        +         P ++  FA       +SD  ++D
Sbjct: 126 IDS--NDLSEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVD 183

Query: 169 QWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGI 228
                 +   +      Q    A   +  ++   +D   H   P+S     K       +
Sbjct: 184 NNVTRNLPGKL-----FQEW--AQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSIL 236

Query: 229 RQTYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAG-VKRSAPNPG 284
           +  Y+      +D  T   +  D+G++    HGG          +       + + P   
Sbjct: 237 KSIYDEVLEHEDDDDTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARPESQ 296

Query: 285 QNFTAGENGP----ILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQ 340
            N+T   N         L  ++QI + P ++AL G+P PMN++ ++   FL         
Sbjct: 297 VNYTLPINASPDWNFQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFL--------- 347

Query: 341 VLHLNAMQLLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEAL 400
                  QLL      +K   +  ++L   K          +              +E L
Sbjct: 348 -------QLLPNKLASMK---ENFMHLW--KLSDHHGEVALDDFTAEDIYTKMYTIQETL 395

Query: 401 KVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYLLLVRLARES 448
             S                 Y+ PLL      +L+   + +  L R S
Sbjct: 396 TKSA--------------TNYNYPLLTLAFVGFLIITIIAIYVLLRYS 429
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  338 bits (859), Expect = 3e-91
 Identities = 68/410 (16%), Positives = 130/410 (31%), Gaps = 31/410 (7%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSD--LEPLSTLRELGLEPPADRLVVFVVDGLRA 58
           +W    L V +++L     + F    L    L P  T   +  E P  + ++ VVD  R+
Sbjct: 2   LWKRWTLAVTIVVLQLAAVLLFARGFLPSRVLLPGYTESRVSTEAPFQKAIIMVVDAFRS 61

Query: 59  QSVLADHCSAVPDLRELFVEQALV-GISRACPPTVTRPGHIAIFGGFNEDPAATLTWNP- 116
               +D  S  P L +       +   + + PPTVT P    +  G   +    +     
Sbjct: 62  DFAFSDQ-SNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAE 120

Query: 117 -STFDSVFNRSRNA-IGWMQAEVAKVFTHLPT-GGAPLRFET---FARSDISDRLRLDQW 170
                ++ N+               +F         P  F+     A   +SD   +D  
Sbjct: 121 SDNSSTLANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNN 180

Query: 171 TFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQ 230
               +   +  +            +  ++   +D   H   P S     K         +
Sbjct: 181 VTRHIDTQLDQKT--------EWDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDK 232

Query: 231 TYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPGQNF 287
            Y        D  T  ++  D+G++    HGG          +      + +        
Sbjct: 233 LYNSC-----DDDTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAET 287

Query: 288 TA-GENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNT-SVQYELQVLHLN 345
           +            +++Q  L P ++AL+GL  P NN+ ++    L   S + +L VL  N
Sbjct: 288 SPLPWTDTYKYHSRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNN 347

Query: 346 AMQ--LLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAK 393
           A Q   + Q +   +     +  L      +    +  N+    +  +  
Sbjct: 348 ADQMVQILQGQASRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTH 397
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  320 bits (813), Expect = 7e-86
 Identities = 69/378 (18%), Positives = 117/378 (30%), Gaps = 63/378 (16%)

Query: 8   VVHLLLLGSILSIY-----FQSTIL---SDLEPLSTLRELGLEP---------------- 43
            V L L       Y     F S  L    +L   S+ +E                     
Sbjct: 5   SVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMA 64

Query: 44  -PADRLVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFG 102
               R+V+ ++D LR       H      + E+    A +  S+  PPT T     A+  
Sbjct: 65  SRFSRVVLVLIDALRFDFAQPQHSHR---ILEIQPHHARLYRSQVDPPTTTMQRLKALTT 121

Query: 103 GFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDIS 162
           G         +   S    V +     +      V  +         P  F         
Sbjct: 122 GSLPTFIDAGSNFAS-HAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKAFFFPSF 180

Query: 163 DRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLN 222
           +   LD      + +          +      +   +   +D   H H P+     +KL+
Sbjct: 181 NVRDLDTVDNGILEHLYPT------MDSGEWDVLIAHFLGVDHCGHKHGPHHPEMAKKLS 234

Query: 223 YTQRGIRQTYELFESVFNDSRTAYLMTADYGISL---HGGGGERGVETPFILWGAGVKRS 279
              + I+   E  E     + T  ++  D+G++    HGG  E  V     L+       
Sbjct: 235 QMDQVIQGLVERLE-----NDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYSPTAVFP 289

Query: 280 APNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLN------- 332
           +       T  E   ++P     Q+ L P ++ L+GLP P  N+  +     +       
Sbjct: 290 S-------TPPEEPEVIP-----QVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQP 337

Query: 333 -TSVQYELQVLHLNAMQL 349
            +S   +   LHLNA Q+
Sbjct: 338 HSSALAQASALHLNAQQV 355
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  309 bits (784), Expect = 2e-82
 Identities = 77/440 (17%), Positives = 134/440 (29%), Gaps = 83/440 (18%)

Query: 7   LVVHLLLLGSILSI-----YFQSTILSDLEPL---STLRELG------------------ 40
           L    +L+     I      F    L         ST R L                   
Sbjct: 3   LTYLFVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIF 62

Query: 41  ---------LEPPADRLVVFVVDGLRAQSVL--ADHCSAVPDLRELF---------VEQA 80
                      P   +++V VVD L+ +  L  A+    +P   +L           + A
Sbjct: 63  KDVNASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHA 122

Query: 81  LVGISRACPPTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKV 140
            +   RA PPT T      +  G         +   S      N        ++ ++  V
Sbjct: 123 RLMRFRADPPTTTLQRLKGLTTGSLPTFIDIGSNFAS---PEINEDNIIDQIVKNDLPVV 179

Query: 141 FTHLPTG--GAPLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFV 198
           F    T     P RF+        D   LD    + +++        + L      +   
Sbjct: 180 FLGDSTWTDLYPHRFKRSYSYPSFDIFDLDSVDNEILKHL------PKELESKDWQVLVA 233

Query: 199 YLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGISL-- 256
           +   +D   H H P       KL      IR           D+ T  L+  D+G++   
Sbjct: 234 HFLGVDHCGHKHGPMHEEMARKLGEMNEVIRSVVAAM-----DNDTTLLVMGDHGMTASG 288

Query: 257 -HGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIG 315
            HGG  +         +            +      N        L+QI L P ++ ++G
Sbjct: 289 DHGGDTDDETNALLFAYS-----------KQHRFYGNDSGSDSEMLQQIDLVPTLATILG 337

Query: 316 LPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQ-LLAQARILIKRHEDGILYLLLPKFES 374
           +P P +N+ L+     N ++  +L+V HLN  Q LL  +    ++         L    +
Sbjct: 338 VPIPYSNLGLV-----NFNIVPDLRVPHLNKFQTLLLHSWQNAQQIYRYFFQYALENKRT 392

Query: 375 LGSAEIENYPQIIKYLVAKE 394
               ++++       L+   
Sbjct: 393 FNVEQMDHLETEF-ILLTHR 411
>gb|AAF56711.1| (AE003761) CG13978 gene product [Drosophila melanogaster]
          Length = 475

 Score =  302 bits (768), Expect = 1e-80
 Identities = 121/255 (47%), Positives = 170/255 (66%), Gaps = 5/255 (1%)

Query: 254 ISLHGGGGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSAL 313
           +  HG G    VETP  +WGAGVKR   +   NF    N     + Q++Q QLAPLMS+L
Sbjct: 216 LRAHGSGSPLEVETPLFMWGAGVKRDEIDAEANFPEKPN-----ISQVDQTQLAPLMSSL 270

Query: 314 IGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRHEDGILYLLLPKFE 373
           IGLPPP NN+ALMP+G+LN S +Y+   LHLN +QLL+QA ILI RHE  I Y  LPKF+
Sbjct: 271 IGLPPPKNNLALMPVGYLNVSDEYQAVALHLNVLQLLSQAEILIGRHEKAIFYKWLPKFK 330

Query: 374 SLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASY 433
            L    I+ Y      L ++    +A++   +  KLA++C+ YY+ YY  PL+VA + SY
Sbjct: 331 ELHIGVIDQYAAQFDILKSEGNLTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSY 390

Query: 434 LVWFYLLLVRLARESNHPKSERKGYLTWTTLMMCLGGLVLLELMILQRVPHLTAFYLLLP 493
           ++WFY LL++L R S   K +R+G++T +TL++ + G++L+ +M LQ+VPH+ AFYL+LP
Sbjct: 391 MIWFYCLLLQLTRLSKKEKMQRRGFMTVSTLILAMIGILLIAMMELQKVPHIAAFYLILP 450

Query: 494 FGILILALAERPCQD 508
            G+LI+A AERP  D
Sbjct: 451 VGMLIMAQAERPDID 465
 Score =  260 bits (659), Expect = 7e-68
 Identities = 122/215 (56%), Positives = 158/215 (72%), Gaps = 3/215 (1%)

Query: 1   MWSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQS 60
           MW +QALVVH+LL+G+IL+ YFQ T+L +L P  T+RELGLEPPADRLVVFV DGLRA +
Sbjct: 1   MWKLQALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPADRLVVFVTDGLRAAT 60

Query: 61  VLADHCSAVPDLRELFVEQALVGISRACPPTVTRPGHIAIFGGFNEDPAATLTW---NPS 117
            LA++ S VPDL++++ +Q  +GISR C PT+TRPGHIAIF GF+EDPAA+L     NP 
Sbjct: 61  FLANNGSDVPDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAASLMHLCYNPG 120

Query: 118 TFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRN 177
            FD+VFNRSRN IGW  + +   F  L  GGAPLRF+++   D+ ++L  D+W FDKV N
Sbjct: 121 DFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKLTCDKWAFDKVEN 180

Query: 178 FMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMP 212
           F+ N  NV+  R+    +FFVYLAD+D+A H   P
Sbjct: 181 FLRNVDNVREWRNYKPAVFFVYLADMDIAAHRFKP 215
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  294 bits (746), Expect = 4e-78
 Identities = 73/399 (18%), Positives = 129/399 (32%), Gaps = 83/399 (20%)

Query: 7   LVVHLLLLGSILSIY-----FQSTIL---SDLEPLSTLRELGLEPP-------------- 44
           + V L L       Y     F S  L    +L   S+ +EL    P              
Sbjct: 12  VSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWGSHGKPGACWM 71

Query: 45  ---ADRLVVFVVDGLRAQSVLADHCSA-------VPDLREL---------FVEQALVGIS 85
                R+V+ ++D LR                  VP L +L               +  S
Sbjct: 72  PSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILESQPHHGRLYRS 131

Query: 86  RACPPTVTRPGHIAIFGGFNEDPAATLTWNPS---TFDSVFNRSRNAIGWMQAEVAKVFT 142
           +  PPT T     A+  G         +   S     D+V  +  +A   +       + 
Sbjct: 132 QVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRRVVFMGDDTWR 191

Query: 143 HLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLAD 202
            L  G    +   F+  ++ D   +D    + +            L   +  +   +   
Sbjct: 192 DLFPGAF-SQAFFFSSFNVRDLHTVDNGILEHL---------YPTLDGGSWDVLIAHFLG 241

Query: 203 IDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGISL---HGG 259
           +D   H H P+     +KL+   + I+   E  E     + T  ++  D+G+++   HGG
Sbjct: 242 VDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLE-----NDTLLVVAGDHGMTMNGDHGG 296

Query: 260 GGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPP 319
             E  V     L+       +          E   ++P     Q+ L P ++ L+GLP P
Sbjct: 297 DSELEVSAALFLYSPTALFPS-------VPPEEPEVIP-----QVSLVPTLALLLGLPIP 344

Query: 320 MNNMALMPLGFLN---------TSVQYELQVLHLNAMQL 349
             N   +     +         +S   ++  LH+NA Q+
Sbjct: 345 FGNTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQV 383
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  272 bits (690), Expect = 2e-71
 Identities = 73/408 (17%), Positives = 145/408 (34%), Gaps = 78/408 (19%)

Query: 2   WSIQALVVHLL-LLGSILSIYFQSTILSDLEPLSTLRELGLE------------PPADRL 48
           +++  +++ ++ L   +   +     LS +    + R+   +            P   RL
Sbjct: 14  FTVAGILLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRL 73

Query: 49  VVFVVDGLRAQSVLADHCSA--------VPDLRELFVEQALVGI-SRACPPTVTRPGHIA 99
           +  V+DGL A+ VL              +P  + L      +G  ++A PPTVT P   A
Sbjct: 74  LYQVIDGLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKA 133

Query: 100 IFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFA-- 157
           +  G      A   +    F+       N    +   +   F  +      L  ET+   
Sbjct: 134 MVSG------AIGGFLDVAFN------FNTQALLDDNILGQFFRIGWKMVMLGDETWLKL 181

Query: 158 ------------RSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDL 205
                          + D +++D+     + +          L      +  ++   +D 
Sbjct: 182 FPGLFMRHDGVSSFFVKDTVQVDRNVSRHLPD---------ELNSDDWNLLILHYLGLDH 232

Query: 206 AEHVHMPNSLNFREKLNYTQRGIRQTY--ELFESVFNDSRTAYLMTADYGIS---LHGGG 260
             H    NS     KL      +R  +   + +   +  +T  ++ +D+G++    HGG 
Sbjct: 233 VGHTGGRNSPLMPAKLKEMDDIVRTMHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGS 292

Query: 261 GERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPPM 320
                ++  +  G        N     +A  N          Q+ LAP ++ L G+P P 
Sbjct: 293 SYEETDSLMLFIG-----LNSNISDYASATNNVAF-------QVDLAPTLALLFGVPIPK 340

Query: 321 NNMALMPLGFLNT-SVQYELQVLHLNAMQLLAQARILIKRHEDGILYL 367
           NN+ ++  G L +     +L+ L LN+ QLL   R+++ + +      
Sbjct: 341 NNVGVLVPGTLCSLRDFEQLRALELNSWQLL---RLMLAQIQSSSFPR 385
>ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Rattus norvegicus]
 gb|AAK69654.1|AF340186_1 (AF340186) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  254 bits (645), Expect = 4e-66
 Identities = 41/303 (13%), Positives = 89/303 (28%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           E   T+         +    ++F +DG RA+ +       +P + +L             
Sbjct: 175 EACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KNCGTY-TKNMR 231

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +     ++     
Sbjct: 232 PVYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PLWYKGQP 287

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                   + D  ++   +       +   + +Q       
Sbjct: 288 IWVTANHQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSYERP 347

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H H P S    + L      +    +  + +  D     ++ +D+G
Sbjct: 348 HFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHG 407

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V    +++G   + R    P   ++         L   +
Sbjct: 408 MEQ---GSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYSFNYEALAKNLSCRE 464

Query: 301 LEQ 303
             Q
Sbjct: 465 TNQ 467
>gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  254 bits (644), Expect = 5e-66
 Identities = 41/303 (13%), Positives = 89/303 (28%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           E   T+         +    ++F +DG RA+ +       +P + +L             
Sbjct: 175 EACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KNCGTY-TKNMR 231

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +     ++     
Sbjct: 232 PVYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PLWYKGQP 287

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                   + D  ++   +       +   + +Q       
Sbjct: 288 IWVTANHQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSYERP 347

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H H P S    + L      +    +  + +  D     ++ +D+G
Sbjct: 348 HFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHG 407

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V    +++G   + R    P   ++         L   +
Sbjct: 408 MEQ---GSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTEVPETYYSFNYEALTKNLSCRE 464

Query: 301 LEQ 303
             Q
Sbjct: 465 TNQ 467
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  251 bits (636), Expect = 4e-65
 Identities = 64/360 (17%), Positives = 111/360 (30%), Gaps = 51/360 (14%)

Query: 27  LSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSVLADHCS-AVPDLRELFVEQALVGIS 85
           L  +E           P  D  V+ +VD LR      D  S  V   R     +      
Sbjct: 51  LLGME------LTPPPPAYDSFVLLLVDALRDDF--PDATSMPVAYSRACEKLKL----- 97

Query: 86  RACPPTVTRPGHIAIFGGFNEDPAATL---TWNPSTFDSVFNRSRNAIGWMQAEVAKVFT 142
               PTVT P   +I  G   +               DS  +R +     +       + 
Sbjct: 98  HVDIPTVTMPRLKSITTGTLSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWV 157

Query: 143 HLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLAD 202
            L       + E      ++D    D+     +            L  +   +  ++   
Sbjct: 158 KLFPSEFTRQVENHDSFYVNDFYEGDRNVTKTLET---------ELERSDWSLLILHYLG 208

Query: 203 IDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGI---SLHGG 259
           +D   HV    S     KL      +++  +     F +     ++T D+G+     HGG
Sbjct: 209 LDHIGHVEGNASPRVPLKLKEMDEVVKKILD--HKSFPN--VLLMLTGDHGMADGGGHGG 264

Query: 260 GGERGVETPFILWGAGVKRSAPNPGQNFTAGENGPILPLYQLEQIQLAPLMSALIGLPPP 319
                   P  L+     +  P+  + +               QI LAP +S L+ +  P
Sbjct: 265 NTPAETLVPLYLYYNNCSK-TPSASKRY--------------NQIDLAPTLSVLLSVEIP 309

Query: 320 MNNMA-LMPLGFLNTSVQYELQVLHLNAMQLLAQARILIKRH--EDGILYLLLPKFESLG 376
             ++  L+P    + S++++L     NA  LL +AR+            Y        L 
Sbjct: 310 TLSIGCLIPEMLQSLSLEHQLYAYFYNAHHLLNKARVKFGHEIVHRSDYYTWYQNATLLH 369
>pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse
          Length = 905

 Score =  250 bits (633), Expect = 9e-65
 Identities = 41/303 (13%), Positives = 90/303 (29%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           E   ++         +    ++F +DG RA+ +       +P + +L             
Sbjct: 175 ETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KNCGTY-TKNMR 231

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +     ++     
Sbjct: 232 PMYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PLWYKGQP 287

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                   + D  ++   +       +   + +Q       
Sbjct: 288 IWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERP 347

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H H P S    + L    R +    +  + +  D     ++ +D+G
Sbjct: 348 HFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG 407

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V    +++G   + R    P   ++         L   +
Sbjct: 408 MEQ---GSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCRE 464

Query: 301 LEQ 303
             Q
Sbjct: 465 PNQ 467
>ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyrophosphatase 1; 1
           ectonucleotide pyrophosphatase/phosphodiesterase 1 [Mus
           musculus]
 gb|AAA39893.2| (J02700) ecto-nucleotide pyrophosphatase/phosphodiesterase-1 [Mus
           musculus domesticus]
          Length = 905

 Score =  250 bits (633), Expect = 9e-65
 Identities = 41/303 (13%), Positives = 90/303 (29%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           E   ++         +    ++F +DG RA+ +       +P + +L             
Sbjct: 175 ETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KNCGTY-TKNMR 231

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +     ++     
Sbjct: 232 PMYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PLWYKGQP 287

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                   + D  ++   +       +   + +Q       
Sbjct: 288 IWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERP 347

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H H P S    + L    R +    +  + +  D     ++ +D+G
Sbjct: 348 HFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG 407

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V    +++G   + R    P   ++         L   +
Sbjct: 408 MEQ---GSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCRE 464

Query: 301 LEQ 303
             Q
Sbjct: 465 PNQ 467
>gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphatase/phosphodiesterase 1
           allotype b [Mus musculus]
          Length = 906

 Score =  250 bits (633), Expect = 9e-65
 Identities = 41/303 (13%), Positives = 90/303 (29%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           E   ++         +    ++F +DG RA+ +       +P + +L             
Sbjct: 175 ETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KNCGTY-TKNMR 231

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +     ++     
Sbjct: 232 PMYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PLWYKGQP 287

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                   + D  ++   +       +   + +Q       
Sbjct: 288 IWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERP 347

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H H P S    + L    R +    +  + +  D     ++ +D+G
Sbjct: 348 HFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG 407

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V    +++G   + R    P   ++         L   +
Sbjct: 408 MEQ---GSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCRE 464

Query: 301 LEQ 303
             Q
Sbjct: 465 PNQ 467
>gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattus norvegicus]
          Length = 906

 Score =  249 bits (632), Expect = 1e-64
 Identities = 40/303 (13%), Positives = 88/303 (28%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           E   T+         +    ++F +DG RA+ +       +P + +L             
Sbjct: 175 EACETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KNCGTY-TKNMR 231

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +     ++     
Sbjct: 232 PVYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PLWYKGQP 287

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                   + D  ++   +       +   + +Q       
Sbjct: 288 IWVTANHQEVRSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSYERP 347

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H H P S    + L      +    +  + +  D     ++ +D+G
Sbjct: 348 HFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKDLGLDKCLNLILISDHG 407

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V    +++G   +      P   ++         L   +
Sbjct: 408 MEQ---GSCKKYVYLNKYLGDVNNVKVVYGPAARLNPPEVPETYYSFNYEALAKNLSCRE 464

Query: 301 LEQ 303
             Q
Sbjct: 465 TNQ 467
>sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Plasma-cell
           membrane glycoprotein PC-1) [Includes: Alkaline
           phosphodiesterase I ; Nucleotide pyrophosphatase
           (NPPASE)]
          Length = 871

 Score =  248 bits (628), Expect = 4e-64
 Identities = 41/303 (13%), Positives = 90/303 (29%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           E   ++         +    ++F +DG RA+ +       +P + +L             
Sbjct: 141 ETCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KNCGTY-TKNMR 197

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +     ++     
Sbjct: 198 PMYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PLWYKGQP 253

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                   + D  ++   +       +   + +Q       
Sbjct: 254 IWVTANHQEVKSGTYFWPGSDVEIDGILPDIYKVYNGSVPFEERILAVLEWLQLPSHERP 313

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H H P S    + L    R +    +  + +  D     ++ +D+G
Sbjct: 314 HFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKDLGLDKCLNLILISDHG 373

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V    +++G   + R    P   ++         L   +
Sbjct: 374 MEQ---GSCKKYVYLNKYLGDVNNVKVVYGPAARLRPTDVPETYYSFNYEALAKNLSCRE 430

Query: 301 LEQ 303
             Q
Sbjct: 431 PNQ 433
>ref|NP_476445.1| (NM_057104) phosphodiesterase I/nucleotide pyrophosphatase 2;
           phosphodiesterase I/nucleotide pyrophosphatase 2
           (autotaxin) [Rattus norvegicus]
 pir||A55453 plasma cell membrane glycoprotein PC-1, brain specific - rat
 dbj|BAA05910.1| (D28560) phosphodiesterase I [Rattus norvegicus]
          Length = 885

 Score =  243 bits (616), Expect = 9e-63
 Identities = 43/225 (19%), Positives = 78/225 (34%), Gaps = 17/225 (7%)

Query: 32  PLSTLRELGLEPPADRLVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACP-- 89
             S+       PP   L++F VDG RA S +      +P++ +L        +    P  
Sbjct: 150 NQSSECLQVCPPP---LIIFSVDGFRA-SYMKKGSKVMPNIEKL-RSCGTH-VPYTRPVY 203

Query: 90  PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGA 149
           PT T P    +  G   +    +    S +D VF+ S +  G  +      F H   GG 
Sbjct: 204 PTKTFPNLYTLATGLYPESHGIVGN--SMYDPVFDASFHLRGREK------FNHRWWGGQ 255

Query: 150 PLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHV 209
           PL + T  +  +         +    R  +T  Q +    +    ++  Y    D + H 
Sbjct: 256 PL-WITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGHK 314

Query: 210 HMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGI 254
           + P        L    + + Q  +  + +        +   D+G+
Sbjct: 315 YGPFGPEMTNPLREIDKTVGQLMDGLKQLRLHRCVNVIFVGDHGM 359
>dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located at nucleotides
           17-19, followed by a second ATG codon 52 codons
           downstream. And the second ATG codon is potential
           initiation point for translation of NPPase. [Homo
           sapiens]
          Length = 930

 Score =  242 bits (614), Expect = 2e-62
 Identities = 43/303 (14%), Positives = 95/303 (31%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           EP  ++ E       +    ++F +DG RA+ +       +P + +L  +          
Sbjct: 198 EPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KKCGTY-TKNMR 254

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +      +     
Sbjct: 255 PVYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PEWYKGEP 310

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                     D  ++   +       +   Q +Q  +D   
Sbjct: 311 IWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERP 370

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H + P S    + L      +    +  + +        ++ +D+G
Sbjct: 371 HFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHG 430

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V+   +++G   + R +  P + ++    G    L   +
Sbjct: 431 MEQ---GSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCRE 487

Query: 301 LEQ 303
             Q
Sbjct: 488 PNQ 490
>pir||A39216 plasma cell membrane glycoprotein PC-1 - human
 gb|AAF36094.1| (AF110304) PDNP1 [Homo sapiens]
 emb|CAC39442.1| (AJ242020) plasma cell membrane glycoprotein [Homo sapiens]
          Length = 925

 Score =  242 bits (613), Expect = 2e-62
 Identities = 43/303 (14%), Positives = 95/303 (31%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           EP  ++ E       +    ++F +DG RA+ +       +P + +L  +          
Sbjct: 193 EPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KKCGTY-TKNMR 249

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +      +     
Sbjct: 250 PVYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PEWYKGEP 305

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                     D  ++   +       +   Q +Q  +D   
Sbjct: 306 IWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERP 365

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H + P S    + L      +    +  + +        ++ +D+G
Sbjct: 366 HFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHG 425

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V+   +++G   + R +  P + ++    G    L   +
Sbjct: 426 MEQ---GSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCRE 482

Query: 301 LEQ 303
             Q
Sbjct: 483 PNQ 485
>gb|AAH03264.1|AAH03264 (BC003264) ectonucleotide pyrophosphatase/phosphodiesterase 2 [Mus
           musculus]
          Length = 862

 Score =  240 bits (609), Expect = 6e-62
 Identities = 41/226 (18%), Positives = 76/226 (33%), Gaps = 16/226 (7%)

Query: 33  LSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACP- 89
              +R         R  L++F VDG RA S +      +P++ +L             P 
Sbjct: 148 CEEIRVPECPAGFVRPPLIIFSVDGFRA-SYMKKGSKVMPNIEKL-RSCGTHA-PYMRPV 204

Query: 90  -PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGG 148
            PT T P    +  G   +    +    S +D VF+ + +  G  +      F H   GG
Sbjct: 205 YPTKTFPNLYTLATGLYPESHGIVGN--SMYDPVFDATFHLRGREK------FNHRWWGG 256

Query: 149 APLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEH 208
            PL + T  +  +         +    R  +T  Q +    +    ++  Y    D + H
Sbjct: 257 QPL-WITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGH 315

Query: 209 VHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGI 254
            + P        L    + + Q  +  + +        +   D+G+
Sbjct: 316 KYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGM 361
>ref|NP_056559.1| (NM_015744) phosphodiesterase I/nucleotide pyrophosphatase 2 [Mus
           musculus]
 gb|AAD46480.1|AF123542_1 (AF123542) phosphodiesterase I/nucleotide pyrophosphatase [Mus
           musculus]
          Length = 862

 Score =  240 bits (609), Expect = 7e-62
 Identities = 41/226 (18%), Positives = 76/226 (33%), Gaps = 16/226 (7%)

Query: 33  LSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACP- 89
              +R         R  L++F VDG RA S +      +P++ +L             P 
Sbjct: 148 CEEIRVPECPAGFVRPPLIIFSVDGFRA-SYMKKGSKVMPNIEKL-RSCGTHA-PYMRPV 204

Query: 90  -PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGG 148
            PT T P    +  G   +    +    S +D VF+ + +  G  +      F H   GG
Sbjct: 205 YPTKTFPNLYTLATGLYPESHGIVGN--SMYDPVFDATFHLRGREK------FNHRWWGG 256

Query: 149 APLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEH 208
            PL + T  +  +         +    R  +T  Q +    +    ++  Y    D + H
Sbjct: 257 QPL-WITATKQGVRAGTFFWSVSIPHERRILTILQWLSLPDNERPSVYAFYSEQPDFSGH 315

Query: 209 VHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGI 254
            + P        L    + + Q  +  + +        +   D+G+
Sbjct: 316 KYGPFGPEMTNPLREIDKTVGQLMDGLKQLKLHRCVNVIFVGDHGM 361
>ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phosphodiesterase 1;
           phosphodiesterase I/nucleotide pyrophosphatase 1
           (homologous to mouse Ly-41 antigen); plasma-cell
           membrane glycoprotein [Homo sapiens]
 sp|P22413|PC1_HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (PLASMA-CELL
           MEMBRANE GLYCOPROTEIN PC-1) [INCLUDES: ALKALINE
           PHOSPHODIESTERASE I ; NUCLEOTIDE PYROPHOSPHATASE
           (NPPASE)]
 gb|AAA63237.1| (M57736) plasma cell membrane glycoprotein PC-1 [Homo sapiens]
 dbj|BAA02054.1| (D12485) NPPase [Homo sapiens]
          Length = 873

 Score =  239 bits (606), Expect = 1e-61
 Identities = 43/303 (14%), Positives = 95/303 (31%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           EP  ++ E       +    ++F +DG RA+ +       +P + +L  +          
Sbjct: 141 EPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KKCGTY-TKNMR 197

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +      +     
Sbjct: 198 PVYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PEWYKGEP 253

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                     D  ++   +       +   Q +Q  +D   
Sbjct: 254 IWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERP 313

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H + P S    + L      +    +  + +        ++ +D+G
Sbjct: 314 HFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHG 373

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V+   +++G   + R +  P + ++    G    L   +
Sbjct: 374 MEQ---GSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCRE 430

Query: 301 LEQ 303
             Q
Sbjct: 431 PNQ 433
>dbj|BAA08260.1| (D45421) phosphodiesterase I alpha [Homo sapiens]
          Length = 863

 Score =  239 bits (606), Expect = 1e-61
 Identities = 40/226 (17%), Positives = 74/226 (32%), Gaps = 16/226 (7%)

Query: 33  LSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACP- 89
              ++         R  L++F VDG RA S +      +P++ +L             P 
Sbjct: 149 CEEIKAAECPAGFVRPPLIIFSVDGFRA-SYMKKGSKVMPNIEKL-RSCGTHS-PYMRPV 205

Query: 90  -PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGG 148
            PT T P    +  G   +    +    S +D VF+ + +  G  +      F H   GG
Sbjct: 206 YPTKTFPNLYTLATGLYPESHGIVGN--SMYDPVFDATFHLRGREK------FNHRWWGG 257

Query: 149 APLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEH 208
            PL + T  +  +              R  +T  Q +         ++  Y    D + H
Sbjct: 258 QPL-WITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGH 316

Query: 209 VHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGI 254
            + P        L    + + Q  +  + +        +   D+G+
Sbjct: 317 KYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362
>ref|NP_006200.1| (NM_006209) ectonucleotide pyrophosphatase/phosphodiesterase 2
           (autotaxin); Phosphodiesterase I/nucleotide
           pyrophosphatase 2; autotaxin; phosphodiesterase
           I/nucleotide pyrophosphatase 2 (autotaxin) [Homo
           sapiens]
 gb|AAB00855.1| (L46720) autotaxin-t [Homo sapiens]
          Length = 863

 Score =  239 bits (606), Expect = 1e-61
 Identities = 40/226 (17%), Positives = 74/226 (32%), Gaps = 16/226 (7%)

Query: 33  LSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRACP- 89
              ++         R  L++F VDG RA S +      +P++ +L             P 
Sbjct: 149 CEEIKAAECPAGFVRPPLIIFSVDGFRA-SYMKKGSKVMPNIEKL-RSCGTHS-PYMRPV 205

Query: 90  -PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGG 148
            PT T P    +  G   +    +    S +D VF+ + +  G  +      F H   GG
Sbjct: 206 YPTKTFPNLYTLATGLYPESHGIVGN--SMYDPVFDATFHLRGREK------FNHRWWGG 257

Query: 149 APLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEH 208
            PL + T  +  +              R  +T  Q +         ++  Y    D + H
Sbjct: 258 QPL-WITATKQGVKAGTFFWSVVIPHERRILTILQWLTLPDHERPSVYAFYSEQPDFSGH 316

Query: 209 VHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGI 254
            + P        L    + + Q  +  + +        +   D+G+
Sbjct: 317 KYGPFGPEMTNPLREIDKIVGQLMDGLKQLKLHRCVNVIFVGDHGM 362
>emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucleotide
           pyrophosphatase 1 (homologous to mouse Ly-41 antigen)
           (PC1, NPPS)) [Homo sapiens]
          Length = 845

 Score =  238 bits (603), Expect = 3e-61
 Identities = 43/303 (14%), Positives = 95/303 (31%), Gaps = 40/303 (13%)

Query: 31  EPLSTLRELGLEPPADR--LVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC 88
           EP  ++ E       +    ++F +DG RA+ +       +P + +L  +          
Sbjct: 113 EPCESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGG-LLPVISKL-KKCGTY-TKNMR 169

Query: 89  P--PTVTRPGHIAIFGGFNEDPAATLTWNPSTFDSVFNRSRNAIGWMQAEVAKVFTHLP- 145
           P  PT T P H +I  G   +    +  +   +D   N S +     +      +     
Sbjct: 170 PVYPTKTFPNHYSIVTGLYPESHGII--DNKMYDPKMNASFSLKSKEKFN--PEWYKGEP 225

Query: 146 -TGGAPLRFETFARSD-----------ISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATS 193
               A  +                     D  ++   +       +   Q +Q  +D   
Sbjct: 226 IWVTAKYQGLKSGTFFWPGSDVEINGIFPDIYKMYNGSVPFEERILAVLQWLQLPKDERP 285

Query: 194 VIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYG 253
             + +YL + D + H + P S    + L      +    +  + +        ++ +D+G
Sbjct: 286 HFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKELNLHRCLNLILISDHG 345

Query: 254 ISLHGGGG----------ERGVETPFILWGAGVK-RSAPNPGQNFTAGENGP--ILPLYQ 300
           +     G              V+   +++G   + R +  P + ++    G    L   +
Sbjct: 346 MEQ---GSCKKYIYLNKYLGDVKNIKVIYGPAARLRPSDVPDKYYSFNYEGIARNLSCRE 402

Query: 301 LEQ 303
             Q
Sbjct: 403 PNQ 405
>ref|NP_491098.1| (NM_058697) M01B12.2.p [Caenorhabditis elegans]
 pir||T33168 hypothetical protein M01B12.2 - Caenorhabditis elegans
          Length = 559

 Score =  212 bits (535), Expect = 2e-53
 Identities = 44/225 (19%), Positives = 91/225 (39%), Gaps = 15/225 (6%)

Query: 649 CTYVYAACWSYLLFAFLSIPYSGTKDLRRRLELIIFNMLTVHIMLTTSIGSLFVQIMVTE 708
            +      W+ +  + ++        L  RL          + +L+ S  SLF+ I +  
Sbjct: 303 PSIARWISWTSIPLSVIAPSLLTGPYLVDRLIAYALCFYVPYSLLSISYESLFMLIFLVL 362

Query: 709 FVLGLELYEESFSYANLKDAIANQQQNNQGLEESRNESPNNPLEHVRQSYRYAALILLYL 768
             L +       S   L     +  + + G             E+V    R   + + ++
Sbjct: 363 LTLFVRFEFGHLSDVELLQLKVDSTKISTG-------------EYVE--LRRTVVCVSFV 407

Query: 769 YISFFGTGHWFFNFTFKPMTSRLFFPQFHLHMLVAFILLKIFIPSIIVMSSIYALVSFGR 828
               FGTG++    +F P T  LF   F    +   ++LK+ IP ++V S+  ++V F +
Sbjct: 408 LCPLFGTGNFASINSFNPSTLNLFISVFSPFTMAILLILKLLIPILLVTSAFASIVRFDQ 467

Query: 829 KNVRSIFICLFLMNDAMSLYFCYFVINRGSLEKVRESLDRLLVSH 873
           ++++ +     +  D MS+ F + + + GS   +  S+ + +VS 
Sbjct: 468 ESIQRLCCFSLIFTDFMSMCFFHQLRDEGSWLDIGMSISQFIVSM 512
 Score =  158 bits (398), Expect = 3e-37
 Identities = 35/225 (15%), Positives = 73/225 (31%), Gaps = 26/225 (11%)

Query: 380 IENYPQIIKYLVAKEQYEEALKVSHKIAKLAQECMEYYHGYYHLPLLVATTASYLVWFYL 439
           +E+    +  L    ++  A  +    A L +E + +YH Y    L  A + S++ W   
Sbjct: 1   MESLRTTLAQLGRDRRFSVATSLFADNAHLMKEAIVFYHRYDRQMLGAAVSCSFVAWI-- 58

Query: 440 LLVRLARESNHPKSERKGYLTWTTLM--MCLGGLVLLELMILQRVPHLTAFYLLLPFGIL 497
             + ++   N    E    L    L        L+      L     +     +    IL
Sbjct: 59  -ALVVSFLHNSTSKENLSLLVPHHLFIIPLACSLLFTAYCSLSMTQTIYIILPIYLISIL 117

Query: 498 -------------ILALAERP---CQDRDL-MCQFPVLHLVGIVMPGVLLILMAFHNSHI 540
                        + AL+ +P    +   + +   P L  VG  +   + +L     + +
Sbjct: 118 ENHSKLTQRIREHVKALSAQPDWLNKVLSVEVFVKPFLGFVGFSITICIFVLTFMDRAFL 177

Query: 541 GLLYLPIVCLNNRRAFFRPSLKLIF--WLALVFLLSGILLVKQSA 583
             +++ ++ L     +  P +      WL L  +L     +    
Sbjct: 178 AAVFVLLMALPQF--YSHPIVSYWSKTWLTLCLVLCIFPFLPAVG 220
>dbj|BAA87261.1| (AB027957) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 179

 Score =  209 bits (527), Expect = 2e-52
 Identities = 47/174 (27%), Positives = 89/174 (51%), Gaps = 7/174 (4%)

Query: 190 DATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESVF-NDSRTAYLM 248
               ++FF++L  ID   H   P+S+ + E + Y    I++  +   + + ND  ++++ 
Sbjct: 1   HRDKIVFFLHLLGIDTIGHNKHPDSVEYVENIQYIDGKIQELVDKMNNYYNNDGASSWVF 60

Query: 249 TADYGIS---LHGGGGERGVETPFILWGAGVKRSAPNPG---QNFTAGENGPILPLYQLE 302
           TAD+G+S    HG G      TP I WGAG++            ++   N   +    ++
Sbjct: 61  TADHGMSDFGSHGDGNLDNTRTPIIAWGAGIQSPTHEKNYGHDEYSLPWNLTEIKRIDIQ 120

Query: 303 QIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQLLAQARIL 356
           Q  +A LMS L+GL  P+N++  +PL +L+ S + + +V  +NA+++  Q  + 
Sbjct: 121 QADIAALMSYLVGLNFPVNSVGQIPLDYLDCSSRRKAEVALMNALEIGEQYNLK 174
>ref|NP_281901.1| (NC_002163) hypothetical protein Cj0729 [Campylobacter jejuni]
 pir||D81344 hypothetical protein Cj0729 [imported] - Campylobacter jejuni
           (strain NCTC 11168)
 emb|CAB73003.1| (AL139076) hypothetical protein Cj0729 [Campylobacter jejuni]
          Length = 269

 Score =  195 bits (493), Expect = 2e-48
 Identities = 43/251 (17%), Positives = 87/251 (34%), Gaps = 21/251 (8%)

Query: 46  DRLVVFVVDGLRAQSVLADHCSAVPDLRELFVEQALVGISRAC-PPTVTRPGHIAIFGGF 104
            + ++ V+DGL            +  L  L  E      S  C  P+++RP +  +  G 
Sbjct: 3   SKAILVVLDGLNC----KSASINMGYLNALCKENLGKFYSLECELPSMSRPLYECLLTGV 58

Query: 105 NEDPAATLTW--NPSTFDSVFNRSRNAIGWMQAEVAKVFTHLPTGGAPLRFETFARSDIS 162
               +  +    + S   S+F+  +                L        F       I 
Sbjct: 59  KPVLSGIINNKLSFSKQTSIFDLCKEQGLKAGGAAYHWVFELYNKK---EFIPSLHRHIE 115

Query: 163 DR-LRLDQWTFDKVRNFMTNE--QNVQPLRDATSVIFFV-YLADIDLAEHVHMPNSLNFR 218
           D  L L    F    +++ +    + + LR+  ++ F + +  +ID A H    +S+ + 
Sbjct: 116 DENLTLPYGHFYYEDDYLDSHLFADGEHLRNKYNLDFTLIHSMNIDDAGHKFGSHSIEYA 175

Query: 219 EKLNYTQRGIRQTYELFESVFNDSRTAYLMTADYGIS---LHGGGGERGVETPFILWGAG 275
            K              +   + +     ++T+D+G++    HGG  E  +  PF  +G+ 
Sbjct: 176 NKTKKVD----ILISEYLPTWLEQGINVIITSDHGMTEGKSHGGLSEDEILVPFFTFGSA 231

Query: 276 VKRSAPNPGQN 286
                    Q+
Sbjct: 232 FSYENAKIKQD 242
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  184 bits (463), Expect = 8e-45
 Identities = 34/212 (16%), Positives = 60/212 (28%), Gaps = 21/212 (9%)

Query: 82  VGISRACPPTVTRPGHIAIFGGFNEDPAATL---TWNPSTFDSVFNRSRNAIGWMQAEVA 138
           +  + A PPT +      +  G                   D+  N+           + 
Sbjct: 88  IFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGAPAIVEDNFINQLV----LNGKRLV 143

Query: 139 KVFTHLPTGGAPLRFETFARSDISDRLRLDQWTFDKVRNFMTNEQNVQPLRDATSVIFFV 198
            +     T   P +F+        +   LD      + +          L      +   
Sbjct: 144 MMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHLFPT------LFKDDWDVLIA 197

Query: 199 YLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTYELFESV----FNDSRTAYLMTADYGI 254
           +   +D A H+   +S     KL      + +   + ES          T  ++  D+G 
Sbjct: 198 HFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPGGLHENTMLIVMGDHGQ 257

Query: 255 SL---HGGGGERGVETPFILWGAGVKRSAPNP 283
           +L   HGGG    VET         K +   P
Sbjct: 258 TLNGDHGGGTAEEVETTMFAMSTK-KHTTLVP 288
CPU time:   290.63 user secs.	    3.18 sys. secs	  293.81 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.316    0.178    0.485 

Gapped
Lambda     K      H
   0.270   0.0625    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 674690597
Number of Sequences: 887402
Number of extensions: 40323893
Number of successful extensions: 179254
Number of sequences better than 10.0: 1450
Number of HSP's better than 10.0 without gapping: 145
Number of HSP's successfully gapped in prelim test: 1335
Number of HSP's that attempted gapping in prelim test: 175818
Number of HSP's gapped (non-prelim): 3670
length of query: 919
length of database: 277,845,442
effective HSP length: 56
effective length of query: 863
effective length of database: 228,150,930
effective search space: 196894252590
effective search space used: 196894252590
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.7 bits)
S2: 78 (34.4 bits)