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GPI Anchor Biosynthesis Report: AAAA01008908 (PIG-K family, Oryza sativa)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (404 letters)

Database: nr
           1,315,992 sequences; 421,297,171 total letters

Searching..................................................

Distribution of 51 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Score E Sequences producing significant alignments: (bits) Value ref|NP_563825.1| putative GPI-anchor transamidase (U32517); p... 534 e-150 gb|AAM61446.1| putative GPI-anchor transamidase [Arabidopsis ... 533 e-150 pir||T00731 hypothetical protein F22O13.26 - Arabidopsis thal... 494 e-138 gb|AAF99765.1|AC003981_15 F22O13.24 [Arabidopsis thaliana] 485 e-136 ref|NP_005473.1| phosphatidylinositol glycan, class K precurs... 357 3e-97 ref|NP_569968.2| CG4406-PA [Drosophila melanogaster] >gi|1952... 357 4e-97 emb|CAA68871.1| gpi8 [Homo sapiens] 357 4e-97 pir||T13411 hypothetical protein 133E12.3 - fruit fly (Drosop... 355 1e-96 gb|AAH26186.1| Similar to phosphatidylinositol glycan, class ... 349 8e-95 ref|NP_010618.1| Protein involved in the attachment of glycos... 346 6e-94 gb|EAA09153.1| agCP14127 [Anopheles gambiae str. PEST] 342 1e-92 ref|XP_131206.1| RIKEN cDNA 3000001O05 [Mus musculus] >gi|263... 341 2e-92 dbj|BAC31442.1| unnamed protein product [Mus musculus] 337 2e-91 sp|Q9CXY9|GPI8_MOUSE GPI-anchor transamidase (GPI transamidas... 330 3e-89 ref|NP_588198.1| putative gpi-anchor transamidase [Schizosacc... 317 3e-85 emb|CAD44992.1| GPI transamidase 8 [Toxoplasma gondii] 304 2e-81 ref|NP_502076.1| Peptidase C13 family [Caenorhabditis elegans... 292 8e-78 emb|CAC67556.1| Gpi8 transamidase [Trypanosoma brucei] >gi|20... 206 9e-52 dbj|BAC32653.1| unnamed protein product [Mus musculus] 193 7e-48 emb|CAB55340.1| GPI:protein transamidase [Leishmania mexicana] 184 2e-45 gb|AAL29895.1| GPI8 transamidase [Paramecium tetraurelia] 140 6e-32 ref|NP_701158.1| GPI8p transamidase [Plasmodium falciparum 3D... 116 1e-24 gb|AAF73260.1|AF154349_1 legumain [Rattus norvegicus] 114 4e-24 ref|NP_071562.1| protease, cysteine, 1 (legumain) [Rattus nor... 114 4e-24 ref|NP_035305.1| legumain; protease, cysteine, 1; preprolegum... 112 2e-23 emb|CAB71158.1| asparaginyl endopeptidase [Schistosoma mansoni] 111 3e-23 dbj|BAB69947.1| legumain [Bos taurus] 110 9e-23 dbj|BAA09530.1| cysteine protease [Homo sapiens] 109 1e-22 ref|NP_005597.2| legumain; protease, cysteine, 1 (legumain) [... 108 3e-22 sp|Q99538|LGMN_HUMAN Legumain precursor (Asparaginyl endopept... 108 3e-22 sp|P09841|HGLB_SCHMA Hemoglobinase precursor (Antigen SM32) >... 107 6e-22 dbj|BAA90621.1| Similar to Phaseolus vulgaris Moldavian encod... 106 9e-22 ref|NP_506137.1| Peptidase C13 family (53.2 kD) [Caenorhabdit... 106 1e-21 gb|AAA29895.1| hemoglobinase 103 8e-21 sp|P42665|HGLB_SCHJA Hemoglobinase precursor (Antigen Sj32) >... 103 8e-21 emb|CAB51545.1| vacuolar processing enzyme [Lycopersicon escu... 103 9e-21 gb|EAA15187.1| GPI8p transamidase-related [Plasmodium yoelii ... 103 1e-20 dbj|BAC54829.1| vacuolar processing enzyme-2 [Nicotiana tabacum] 101 3e-20 ref|NP_180165.1| putative vacuolar processing enzyme; protein... 100 5e-20 gb|AAF21773.1|AF067448_1 hemoglobinase-type cysteine proteina... 99 2e-19 emb|CAB64544.1| legumain-like protease [Zea mays] 97 9e-19 emb|CAC18099.1| putative legumain [Zea mays] 96 2e-18 dbj|BAC54827.1| vacuolar processing enzyme-1a [Nicotiana taba... 95 2e-18 ref|NP_597033.1| putative PEPTIDASE [Encephalitozoon cuniculi... 94 6e-18 dbj|BAC54830.1| vacuolar processing enzyme-3 [Nicotiana tabacum] 94 7e-18 sp|P49043|VPE_CITSI Vacuolar processing enzyme precursor (VPE... 93 9e-18 dbj|BAC54828.1| vacuolar processing enzyme-1b [Nicotiana taba... 93 2e-17 emb|CAC18100.1| putative legumain [Zea mays] 91 3e-17 gb|AAD04883.1| C13 endopeptidase NP1 precursor [Zea mays] 90 8e-17 dbj|BAA84650.1| asparaginyl endopeptidase [Oryza sativa] >gi|... 84 8e-15
Alignments
>ref|NP_563825.1| putative GPI-anchor transamidase (U32517); protein id: At1g08750.1,
           supported by cDNA: 120167. [Arabidopsis thaliana]
 dbj|BAC42253.1| putative GPI-anchor transamidase [Arabidopsis thaliana]
          Length = 388

 Score =  534 bits (1361), Expect = e-150
 Identities = 275/384 (71%), Positives = 309/384 (79%), Gaps = 7/384 (1%)

Query: 23  LLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDE 82
           L+MLL +S  SS   ++   +H NNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDE
Sbjct: 6   LVMLLCYSFVSSTGDTT---IHTNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDE 62

Query: 83  RIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHE 142
           RIILMLADDMACN RN YPAQVFNNENH+LNLYGDNVEVDYRGYEVTVENFLRVLTGRHE
Sbjct: 63  RIILMLADDMACNARNEYPAQVFNNENHKLNLYGDNVEVDYRGYEVTVENFLRVLTGRHE 122

Query: 143 SAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELL 202
           +AVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQD+EELQSHDLADAVKQMKEK RFKEL+
Sbjct: 123 NAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDAEELQSHDLADAVKQMKEKRRFKELM 182

Query: 203 IMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEKL 262
           IMVDTCQAATLF+QLQSPGVL IGSS+KGENSYSHHLDSDIGVSVVDRFT+YTLAFFE+L
Sbjct: 183 IMVDTCQAATLFNQLQSPGVLAIGSSLKGENSYSHHLDSDIGVSVVDRFTYYTLAFFERL 242

Query: 263 NMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGSVMNTIHTDSAYSGF 322
           N+Y NASLNSLF SY+P +L+STAYYR DLY+  L EVPVTNFFGSVM TIHTDSAY  F
Sbjct: 243 NIYDNASLNSLFRSYDPRLLMSTAYYRTDLYQPHLVEVPVTNFFGSVMETIHTDSAYKAF 302

Query: 323 LAADDIGTIPSTG--DNLLNHAVLQNKASQRRSNIEEVKEAQV--RSHGWTDVLLEQLDV 378
            +      I S    + L  H + +   +    N E + E Q    S    D+  +   +
Sbjct: 303 SSKISERKINSEMPFNQLSEHDLKEELENTNIPNDELIAEKQKCPYSQMRADLHEKVEKL 362

Query: 379 KNADTIVMYGLGTMGILLAISTWL 402
           +N DT+V   +  M + + +S+ L
Sbjct: 363 ENVDTVVNLSIAVMVLAVMVSSSL 386
>gb|AAM61446.1| putative GPI-anchor transamidase [Arabidopsis thaliana]
          Length = 388

 Score =  533 bits (1359), Expect = e-150
 Identities = 275/384 (71%), Positives = 309/384 (79%), Gaps = 7/384 (1%)

Query: 23  LLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDE 82
           L+MLL +S  SS   ++   +H NNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDE
Sbjct: 6   LVMLLCYSFVSSTGDTT---IHTNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDE 62

Query: 83  RIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHE 142
           RIILMLADDMACN RN YPAQVFNNENH+LNLYGDNVEVDYRGYEVTVENFLRVLTGRHE
Sbjct: 63  RIILMLADDMACNARNEYPAQVFNNENHKLNLYGDNVEVDYRGYEVTVENFLRVLTGRHE 122

Query: 143 SAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELL 202
           +AVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQD+EELQSHDLADAVKQMKEK RFKEL+
Sbjct: 123 NAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDAEELQSHDLADAVKQMKEKRRFKELM 182

Query: 203 IMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEKL 262
           IMVDTCQAATLF+QLQSPGVL IGSS+KGENSYSHHLDSDIGVSVVDRFT+YTLAFFE+L
Sbjct: 183 IMVDTCQAATLFNQLQSPGVLAIGSSLKGENSYSHHLDSDIGVSVVDRFTYYTLAFFERL 242

Query: 263 NMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGSVMNTIHTDSAYSGF 322
           N+Y NASLNSLF SY+P +L+STAYYR DLY+  L EVPVTNFFGSVM TIHTDSAY  F
Sbjct: 243 NIYDNASLNSLFRSYDPRLLMSTAYYRTDLYQPHLVEVPVTNFFGSVMETIHTDSAYKAF 302

Query: 323 LAADDIGTIPSTG--DNLLNHAVLQNKASQRRSNIEEVKEAQV--RSHGWTDVLLEQLDV 378
            +      I S    + L  H + +   +    N E + E Q    S    D+  +   +
Sbjct: 303 SSKISERKINSEMPFNQLSEHDLKEELENTNIPNDELIAEKQKCPYSQMRADLHEKVEKL 362

Query: 379 KNADTIVMYGLGTMGILLAISTWL 402
           +N DT+V   +  M + + +S+ L
Sbjct: 363 ENVDTVVNLSIALMVLAVMVSSSL 386
>pir||T00731 hypothetical protein F22O13.26 - Arabidopsis thaliana
          Length = 428

 Score =  494 bits (1259), Expect = e-138
 Identities = 245/304 (80%), Positives = 266/304 (86%), Gaps = 7/304 (2%)

Query: 23  LLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFW----FNYRHMANTLSLYRTVKRLG 78
           L+MLL +S  SS   ++   +H NNWAVLVCTSRF          + + L + RTVKRLG
Sbjct: 6   LVMLLCYSFVSSTGDTT---IHTNNWAVLVCTSRFCSLHSLVLTFIFSLLGVSRTVKRLG 62

Query: 79  IPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLT 138
           IPDERIILMLADDMACN RN YPAQVFNNENH+LNLYGDNVEVDYRGYEVTVENFLRVLT
Sbjct: 63  IPDERIILMLADDMACNARNEYPAQVFNNENHKLNLYGDNVEVDYRGYEVTVENFLRVLT 122

Query: 139 GRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRF 198
           GRHE+AVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQD+EELQSHDLADAVKQMKEK RF
Sbjct: 123 GRHENAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDAEELQSHDLADAVKQMKEKRRF 182

Query: 199 KELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAF 258
           KEL+IMVDTCQAATLF+QLQSPGVL IGSS+KGENSYSHHLDSDIGVSVVDRFT+YTLAF
Sbjct: 183 KELMIMVDTCQAATLFNQLQSPGVLAIGSSLKGENSYSHHLDSDIGVSVVDRFTYYTLAF 242

Query: 259 FEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGSVMNTIHTDSA 318
           FE+LN+Y NASLNSLF SY+P +L+STAYYR DLY+  L EVPVTNFFGSVM TIHTDSA
Sbjct: 243 FERLNIYDNASLNSLFRSYDPRLLMSTAYYRTDLYQPHLVEVPVTNFFGSVMETIHTDSA 302

Query: 319 YSGF 322
           Y  F
Sbjct: 303 YKAF 306
>gb|AAF99765.1|AC003981_15 F22O13.24 [Arabidopsis thaliana]
          Length = 407

 Score =  485 bits (1236), Expect = e-136
 Identities = 241/300 (80%), Positives = 259/300 (86%), Gaps = 20/300 (6%)

Query: 23  LLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDE 82
           L+MLL +S  SS   ++   +H NNWAVLVCTSRFW              TVKRLGIPDE
Sbjct: 6   LVMLLCYSFVSSTGDTT---IHTNNWAVLVCTSRFW--------------TVKRLGIPDE 48

Query: 83  RIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHE 142
           RIILMLADDMACN RN YPAQVFNNENH+LNLYGDNVEVDYRGYEVTVENFLRVLTGRHE
Sbjct: 49  RIILMLADDMACNARNEYPAQVFNNENHKLNLYGDNVEVDYRGYEVTVENFLRVLTGRHE 108

Query: 143 SAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELL 202
           +AVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQD+EELQSHDLADAVKQMKEK RFKEL+
Sbjct: 109 NAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDAEELQSHDLADAVKQMKEKRRFKELM 168

Query: 203 IMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEKL 262
           IMVDTCQAATLF+QLQSPGVL IGSS+KGENSYSHHLDSDIGVSVVDRFT+YTLAFFE+L
Sbjct: 169 IMVDTCQAATLFNQLQSPGVLAIGSSLKGENSYSHHLDSDIGVSVVDRFTYYTLAFFERL 228

Query: 263 NMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGSVMNTIHTDSAYSGF 322
           N+Y NASLN    SY+P +L+STAYYR DLY+  L EVPVTNFFGSVM TIHTDSAY  F
Sbjct: 229 NIYDNASLN---RSYDPRLLMSTAYYRTDLYQPHLVEVPVTNFFGSVMETIHTDSAYKAF 285
>ref|NP_005473.1| phosphatidylinositol glycan, class K precursor [Homo sapiens]
 sp|Q92643|GPI8_HUMAN GPI-anchor transamidase (GPI transamidase)
           (Phosphatidylinositol-glycan biosynthesis, class K
           protein) (PIG-K) (hGPI8)
 gb|AAB81597.1| GPI transamidase [Homo sapiens]
 gb|AAH20737.1|AAH20737 Unknown (protein for MGC:22559) [Homo sapiens]
          Length = 395

 Score =  357 bits (907), Expect = 3e-97
 Identities = 172/303 (56%), Positives = 224/303 (73%), Gaps = 8/303 (2%)

Query: 12  SRALLVLLLPALLMLLAFSTSSSAAASSPGAM-----HNNNWAVLVCTSRFWFNYRHMAN 66
           SRA  VL   A ++LL+F + +++             H NNWAVLVCTSRFWFNYRH+AN
Sbjct: 8   SRAATVL---ATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVAN 64

Query: 67  TLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGY 126
           TLS+YR+VKRLGIPD  I+LMLADDMACNPRN  PA VF+++N +LN+YGD+VEVDYR Y
Sbjct: 65  TLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSY 124

Query: 127 EVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLA 186
           EVTVENFLRVLTGR   + PRSKRLLSD+ S+IL+YMTGHGG+ FLKFQDSEE+ + +LA
Sbjct: 125 EVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELA 184

Query: 187 DAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVS 246
           DA +QM +K R+ ELL ++DTCQ A+++ +  SP ++ + SS  GE+S SH  D  IGV 
Sbjct: 185 DAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVH 244

Query: 247 VVDRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFF 306
           ++DR+TFY L F E++N  S  ++N LF     S+ +ST  +R DL++R    V +T+FF
Sbjct: 245 LMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFF 304

Query: 307 GSV 309
           GSV
Sbjct: 305 GSV 307
>ref|NP_569968.2| CG4406-PA [Drosophila melanogaster]
 gb|AAL89972.1| AT02512p [Drosophila melanogaster]
 gb|AAF45703.2| CG4406-PA [Drosophila melanogaster]
          Length = 355

 Score =  357 bits (906), Expect = 4e-97
 Identities = 161/274 (58%), Positives = 208/274 (75%), Gaps = 1/274 (0%)

Query: 44  HNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQ 103
           H NNWAVLV  SRFWFNYRH+AN LS+YR+VKRLGIPD +IILM+ADDMACN RN  P Q
Sbjct: 43  HTNNWAVLVDASRFWFNYRHVANVLSIYRSVKRLGIPDSQIILMIADDMACNARNPRPGQ 102

Query: 104 VFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYM 163
           V+NN N  +N+YGD+VEVDYRGYEVTVENF+R+LTGR ++   RSK+LLSD GS++L+Y+
Sbjct: 103 VYNNANQHINVYGDDVEVDYRGYEVTVENFVRLLTGRTQNGTARSKKLLSDAGSNVLIYL 162

Query: 164 TGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVL 223
           TGHGGD FLKFQDSEE+ S +LAD ++QM EK R+ EL  MVDTCQAA+L+ +  SP VL
Sbjct: 163 TGHGGDGFLKFQDSEEITSQELADGIQQMWEKKRYNELFFMVDTCQAASLYEKFTSPNVL 222

Query: 224 TIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLL 283
            + SS+ GE+S SHH+D  IGV ++DR+T+Y L F EK+  +S  ++          + +
Sbjct: 223 AVASSLVGEDSLSHHVDPSIGVYMIDRYTYYALEFLEKVQPFSKRTIGEFLQVCPKRVCI 282

Query: 284 STAYYRMDLYERPLNEVPVTNFFGSVMNT-IHTD 316
           ST   R DLY R  ++VP+T+FFG++  T + TD
Sbjct: 283 STVGVRKDLYPRDPHKVPITDFFGAIRPTRVSTD 316
>emb|CAA68871.1| gpi8 [Homo sapiens]
          Length = 396

 Score =  357 bits (906), Expect = 4e-97
 Identities = 172/303 (56%), Positives = 224/303 (73%), Gaps = 8/303 (2%)

Query: 12  SRALLVLLLPALLMLLAFSTSSSAAASSPGAM-----HNNNWAVLVCTSRFWFNYRHMAN 66
           SRA  VL   A ++LL+F + +++             H NNWAVLVCTSRFWFNYRH+AN
Sbjct: 9   SRAATVL---ATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVAN 65

Query: 67  TLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGY 126
           TLS+YR+VKRLGIPD  I+LMLADDMACNPRN  PA VF+++N +LN+YGD+VEVDYR Y
Sbjct: 66  TLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSY 125

Query: 127 EVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLA 186
           EVTVENFLRVLTGR   + PRSKRLLSD+ S+IL+YMTGHGG+ FLKFQDSEE+ + +LA
Sbjct: 126 EVTVENFLRVLTGRIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELA 185

Query: 187 DAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVS 246
           DA +QM +K R+ ELL ++DTCQ A+++ +  SP ++ + SS  GE+S SH  D  IGV 
Sbjct: 186 DAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVH 245

Query: 247 VVDRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFF 306
           ++DR+TFY L F E++N  S  ++N LF     S+ +ST  +R DL++R    V +T+FF
Sbjct: 246 LMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFF 305

Query: 307 GSV 309
           GSV
Sbjct: 306 GSV 308
>pir||T13411 hypothetical protein 133E12.3 - fruit fly (Drosophila melanogaster)
 emb|CAA15687.1| /prediction=(method:''genefinder'', version:''084'',
           score:''46.36'')~/prediction=(method:''genscan'',
           version:''1.0'',
           score:''114.92'')~/match=(desc:''GPI-ANCHOR TRANSMIDASE
           (EC 3.-.-.-)'', species:''SACCHAROMYCES CEREVISIAE
           (BAKER'S YEAST)'', ranges:(query:2691..3173,
           target:SWISS-PROT::P49018:193..33, score:''601.00''),
           (query:2511..2630, target:SWISS-PROT::P49018:227..188,
           score:''140.00''), (query:2357..2467,
           target:SWISS-PROT::P49018:261..225, score:''100.00''),
           (query:2176..2256, target:SWISS-PROT>
          Length = 326

 Score =  355 bits (902), Expect = 1e-96
 Identities = 161/274 (58%), Positives = 208/274 (75%), Gaps = 1/274 (0%)

Query: 44  HNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQ 103
           H NNWAVLV  SRFWFNYRH+AN LS+YR+VKRLGIPD +IILM+ADDMACN RN  P Q
Sbjct: 43  HTNNWAVLVDASRFWFNYRHVANVLSIYRSVKRLGIPDSQIILMIADDMACNARNPRPGQ 102

Query: 104 VFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYM 163
           V+NN N  +N+YGD+VEVDYRGYEVTVENF+R+LTGR ++   RSK+LLSD GS++L+Y+
Sbjct: 103 VYNNANQHINVYGDDVEVDYRGYEVTVENFVRLLTGRTQNGTARSKKLLSDAGSNVLIYL 162

Query: 164 TGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVL 223
           TGHGGD FLKFQDSEE+ S +LAD ++QM EK R+ EL  MVDTCQAA+L+ +  SP VL
Sbjct: 163 TGHGGDGFLKFQDSEEITSQELADGIQQMWEKKRYNELFFMVDTCQAASLYEKFTSPNVL 222

Query: 224 TIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLL 283
            + SS+ GE+S SHH+D  IGV ++DR+T+Y L F EK+  +S  ++          + +
Sbjct: 223 AVASSLVGEDSLSHHVDPSIGVYMIDRYTYYALEFLEKVQPFSKRTIGEFLQVCPKRVCI 282

Query: 284 STAYYRMDLYERPLNEVPVTNFFGSVMNT-IHTD 316
           ST   R DLY R  ++VP+T+FFG++  T + TD
Sbjct: 283 STVGVRKDLYPRDPHKVPITDFFGAIRPTRVSTD 316
>gb|AAH26186.1| Similar to phosphatidylinositol glycan, class K [Homo sapiens]
          Length = 332

 Score =  349 bits (886), Expect = 8e-95
 Identities = 171/303 (56%), Positives = 223/303 (73%), Gaps = 8/303 (2%)

Query: 12  SRALLVLLLPALLMLLAFSTSSSAAASSPGAM-----HNNNWAVLVCTSRFWFNYRHMAN 66
           SRA  VL   A ++LL+F + +++             H NNWAVLVCTSRFWFNYRH+AN
Sbjct: 8   SRAATVL---ATVLLLSFGSVAASHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVAN 64

Query: 67  TLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGY 126
           TLS+YR+VKRLGIPD  I+LMLADDMACNPRN  PA VF+++N +LN+YGD+VEVDYR Y
Sbjct: 65  TLSVYRSVKRLGIPDSHIVLMLADDMACNPRNPKPATVFSHKNMELNVYGDDVEVDYRSY 124

Query: 127 EVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLA 186
           EVTVENFLRVLTG    + PRSKRLLSD+ S+IL+YMTGHGG+ FLKFQDSEE+ + +LA
Sbjct: 125 EVTVENFLRVLTGGIPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELA 184

Query: 187 DAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVS 246
           DA +QM +K R+ ELL ++DTCQ A+++ +  SP ++ + SS  GE+S SH  D  IGV 
Sbjct: 185 DAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVH 244

Query: 247 VVDRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFF 306
           ++DR+TFY L F E++N  S  ++N LF     S+ +ST  +R DL++R    V +T+FF
Sbjct: 245 LMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFF 304

Query: 307 GSV 309
           GSV
Sbjct: 305 GSV 307
>ref|NP_010618.1| Protein involved in the attachment of glycosylphosphatidylinositol
           (GPI) anchors to proteins; Gpi8p [Saccharomyces
           cerevisiae]
 sp|P49018|GPI8_YEAST GPI-anchor transamidase (GPI transamidase)
 pir||S59796 probable membrane protein YDR331w - yeast (Saccharomyces
           cerevisiae)
 gb|AAB64766.1| Ydr331wp [Saccharomyces cerevisiae]
          Length = 411

 Score =  346 bits (879), Expect = 6e-94
 Identities = 172/302 (56%), Positives = 225/302 (73%)

Query: 16  LVLLLPALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVK 75
           L LLL  + +L     +++ AA    A + NNWAVLV TSRFWFNYRHMAN LS+YRTVK
Sbjct: 7   LPLLLLYIFLLPLSGANNTDAAHEVIATNTNNWAVLVSTSRFWFNYRHMANVLSMYRTVK 66

Query: 76  RLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLR 135
           RLGIPD +IILML+DD+ACN RN +P  VFNN++H ++LYGD+VEVDYRGYEVTVENF+R
Sbjct: 67  RLGIPDSQIILMLSDDVACNSRNLFPGSVFNNKDHAIDLYGDSVEVDYRGYEVTVENFIR 126

Query: 136 VLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEK 195
           +LT R     P+SKRLL+DE S+I +YMTGHGGD+FLKFQD+EE+ S D+ADA +QM EK
Sbjct: 127 LLTDRWTEDHPKSKRLLTDENSNIFIYMTGHGGDDFLKFQDAEEIASEDIADAFQQMYEK 186

Query: 196 HRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYT 255
            R+ E+  M+DTCQA T++S+  SP +L +GSS   E+SYSHH D +IGV+V+DRFT+Y 
Sbjct: 187 KRYNEIFFMIDTCQANTMYSKFYSPNILAVGSSEMDESSYSHHSDVEIGVAVIDRFTYYC 246

Query: 256 LAFFEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGSVMNTIHT 315
           L F E+++  S  +L  LF+S+    + S    R DL++R  +EV +T+FF +V N I  
Sbjct: 247 LDFLEQIDKNSTLTLQDLFDSFTFEKIHSHVGVRTDLFDRNPSEVLITDFFANVQNVIPD 306

Query: 316 DS 317
           DS
Sbjct: 307 DS 308
>gb|EAA09153.1| agCP14127 [Anopheles gambiae str. PEST]
          Length = 323

 Score =  342 bits (868), Expect = 1e-92
 Identities = 159/284 (55%), Positives = 208/284 (72%), Gaps = 9/284 (3%)

Query: 29  FSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILML 88
           F TSSS         H NNWAVLV TSRFWFNYRH+AN LS+YR+VKRLGIPD +I+LM+
Sbjct: 5   FVTSSS---------HTNNWAVLVDTSRFWFNYRHIANVLSVYRSVKRLGIPDSQILLMV 55

Query: 89  ADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRS 148
           ADDMACN RN  PA VFNN    +N+YG +VEVDYRGYEVTVENF+R+LTGR+E+   RS
Sbjct: 56  ADDMACNARNPRPATVFNNAKQHINVYGSDVEVDYRGYEVTVENFVRLLTGRNENGTARS 115

Query: 149 KRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTC 208
           KRLLSD GS++L+Y+TGHGGD FLKFQDSEE+ + +LADA++QM +K R+ EL  M+DTC
Sbjct: 116 KRLLSDSGSNVLIYLTGHGGDGFLKFQDSEEITNQELADAIEQMWQKQRYNELFFMIDTC 175

Query: 209 QAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEKLNMYSNA 268
           QAA+++ +  SP +L + SS+ GE+S SHH+D  IGV ++DR+T+  L F E++   S  
Sbjct: 176 QAASMYEKFYSPNILAVASSLVGEDSLSHHIDPAIGVYIIDRYTYNALEFLERVEWNSKK 235

Query: 269 SLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGSVMNT 312
           ++    +       +ST   R DLY +   +VP+T+FFGS+  T
Sbjct: 236 TMGDFLSVCPKRACISTVGVRKDLYPKDPYKVPITDFFGSIRPT 279
>ref|XP_131206.1| RIKEN cDNA 3000001O05 [Mus musculus]
 dbj|BAC37051.1| unnamed protein product [Mus musculus]
 dbj|BAC38629.1| unnamed protein product [Mus musculus]
          Length = 395

 Score =  341 bits (865), Expect = 2e-92
 Identities = 168/301 (55%), Positives = 215/301 (70%), Gaps = 7/301 (2%)

Query: 16  LVLLLPALLMLLAFSTS-------SSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTL 68
           L L +  L  L   S            A     + H NNWAVLVCTSRFWFNYRH+ANTL
Sbjct: 7   LTLRVATLAALALLSLGSSAAGHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTL 66

Query: 69  SLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEV 128
           S+YR+VKRLGIPD  I+LMLADDMACN RN  PA VF+++N +LN+YGD+VEVDYR YEV
Sbjct: 67  SVYRSVKRLGIPDSHIVLMLADDMACNARNPKPATVFSHKNMELNVYGDDVEVDYRSYEV 126

Query: 129 TVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADA 188
           TVENFLRVLTGR   + PRSKRLLSD+ S+IL+YMTGHGG+ FLKFQDSEE+ + +LADA
Sbjct: 127 TVENFLRVLTGRVPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADA 186

Query: 189 VKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVV 248
            +QM +K R+ ELL ++DTCQ A+++ +  SP ++ + SS  GE+S SH  D  IGV ++
Sbjct: 187 FEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLM 246

Query: 249 DRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGS 308
           DR+TFY L F E++N  S  ++N LF     S+ +ST  +R DL++R    V +T+FFGS
Sbjct: 247 DRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGS 306

Query: 309 V 309
           V
Sbjct: 307 V 307
>dbj|BAC31442.1| unnamed protein product [Mus musculus]
          Length = 364

 Score =  337 bits (857), Expect = 2e-91
 Identities = 168/301 (55%), Positives = 215/301 (70%), Gaps = 7/301 (2%)

Query: 16  LVLLLPALLMLLAFSTS-------SSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTL 68
           L L +  L  L   S            A     + H NNWAVLVCTSRFWFNYRH+ANTL
Sbjct: 7   LTLRVATLAALALLSLGSSAAGHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTL 66

Query: 69  SLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEV 128
           S+YR+VKRLGIPD  I+LMLADDMACN RN  PA VF+++N +LN+YGD+VEVDYR YEV
Sbjct: 67  SVYRSVKRLGIPDSHIVLMLADDMACNARNPKPATVFSHKNMELNVYGDDVEVDYRSYEV 126

Query: 129 TVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADA 188
           TVENFLRVLTGR   + PRSKRLLSD+ S+IL+YMTGHGG+ FLKFQDSEE+ + +LADA
Sbjct: 127 TVENFLRVLTGRVPPSTPRSKRLLSDDRSNILIYMTGHGGNGFLKFQDSEEITNIELADA 186

Query: 189 VKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVV 248
            +QM +K R+ ELL ++DTCQ A+++ +  SP ++ + SS  GE+S SH  D  IGV ++
Sbjct: 187 FEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLM 246

Query: 249 DRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGS 308
           DR+TFY L F E++N  S  ++N LF     S+ +ST  +R DL++R    V +T+FFGS
Sbjct: 247 DRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGS 306

Query: 309 V 309
           V
Sbjct: 307 V 307
>sp|Q9CXY9|GPI8_MOUSE GPI-anchor transamidase (GPI transamidase)
           (Phosphatidylinositol-glycan biosynthesis, class K
           protein) (PIG-K)
 dbj|BAB29018.1| unnamed protein product [Mus musculus]
          Length = 395

 Score =  330 bits (839), Expect = 3e-89
 Identities = 163/301 (54%), Positives = 212/301 (70%), Gaps = 7/301 (2%)

Query: 16  LVLLLPALLMLLAFSTS-------SSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTL 68
           L L +  L  L   S            A     + H NNWAVLVCTSRFWFNYRH+ANTL
Sbjct: 7   LTLRVATLAALALLSLGSSAAGHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTL 66

Query: 69  SLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEV 128
           S+YR+VKRLGIPD  I+LMLADDMACN RN  PA VF+++N +LN+YGD+VEVDYR Y  
Sbjct: 67  SVYRSVKRLGIPDSHIVLMLADDMACNARNPKPATVFSHKNMELNVYGDDVEVDYRSYRG 126

Query: 129 TVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADA 188
           TVENFLRVLT     + PRSKRLLSD+ S+IL+YMTGHGG+ FLKFQDSEE+ + +LADA
Sbjct: 127 TVENFLRVLTXEVPPSTPRSKRLLSDDKSNILIYMTGHGGNGFLKFQDSEEITNIELADA 186

Query: 189 VKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVV 248
            +QM +K R+ ELL ++DTCQ A+++ +  SP ++ + SS  GE+S SH  D  IGV ++
Sbjct: 187 FEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMALASSQVGEDSLSHQPDPAIGVHLM 246

Query: 249 DRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGS 308
           DR+TFY L F++++N  S  ++N LF     S+ +ST  +R DL++R    V +T+FFGS
Sbjct: 247 DRYTFYVLEFWKEINPASQTNMNDLFQVCPKSLCVSTPGHRTDLFQRDPKNVLITDFFGS 306

Query: 309 V 309
           V
Sbjct: 307 V 307
>ref|NP_588198.1| putative gpi-anchor transamidase [Schizosaccharomyces pombe]
 sp|Q9USP5|GPI8_SCHPO GPI-anchor transamidase (GPI transamidase)
 pir||T40853 probable cysteine proteinase (EC 3.4.22.-) [similarity] - fission
           yeast (Schizosaccharomyces pombe)
 emb|CAB57844.1| putative gpi-anchor transamidase [Schizosaccharomyces pombe]
 emb|CAC13970.1| GPI8p transamidase [Schizosaccharomyces pombe]
          Length = 380

 Score =  317 bits (805), Expect = 3e-85
 Identities = 159/295 (53%), Positives = 211/295 (70%), Gaps = 12/295 (4%)

Query: 16  LVLLLPALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVK 75
           + LLL  LL ++A  +S           H NNWAVL+ TSRFWFNYRH AN L +YR+VK
Sbjct: 6   VALLLLNLLQIIAAESS-----------HTNNWAVLISTSRFWFNYRHTANVLGIYRSVK 54

Query: 76  RLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLR 135
           RLGIPD +IILM+ADD ACN RN +P  VF+N +  L+LYG+ +E+DY+GYEVTVE F+R
Sbjct: 55  RLGIPDSQIILMIADDYACNSRNLFPGTVFDNADRALDLYGEEIEIDYKGYEVTVEAFIR 114

Query: 136 VLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEK 195
           +LT R     P SKRLL++E S+IL+YMTGHGGD F+KFQD+EEL S DLADA++Q+ + 
Sbjct: 115 LLTERVPENTPASKRLLTNERSNILIYMTGHGGDGFIKFQDAEELSSEDLADAIEQIHQH 174

Query: 196 HRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYT 255
            R+ E+L MVDTCQA +L++++ SP VL IGSS  G +SYSHH D DIGV+V+DRFTF  
Sbjct: 175 KRYNEILFMVDTCQANSLYTKIYSPNVLAIGSSEVGTSSYSHHADIDIGVAVIDRFTFSN 234

Query: 256 LAFFE-KLNMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGSV 309
           L F E +++  S  ++  L NSYNP  + ST   +     R  +++ +T+FFG+V
Sbjct: 235 LEFLENRVDSKSKLTMQDLINSYNPYEIHSTPGVQPINLRRSPDDILITDFFGNV 289
>emb|CAD44992.1| GPI transamidase 8 [Toxoplasma gondii]
          Length = 604

 Score =  304 bits (771), Expect = 2e-81
 Identities = 164/342 (47%), Positives = 215/342 (61%), Gaps = 23/342 (6%)

Query: 1   MASGRGGIP-------------GPSRALLVLLLPALLMLLAFSTSSSAAASSPGAMHNNN 47
           +ASG   I                S  +      +     + S+SS + +S       NN
Sbjct: 41  VASGSSHISPRLRFFLFSLLSLCLSSPVCFSRASSAPSASSRSSSSPSLSSFFSGDFRNN 100

Query: 48  WAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNN 107
           WAV+V TSR+W+NYRH AN LS+Y TVKRLGIPD +IILML+DD AC+PRN +P ++FN+
Sbjct: 101 WAVIVNTSRYWYNYRHTANALSIYHTVKRLGIPDSQIILMLSDDHACSPRNFFPGRIFND 160

Query: 108 ENHQLNLY--------GDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLLSDEGSHI 159
               LNLY        G +VEVDYRG EV V   L++L GRH  A PR KRLL+DE S +
Sbjct: 161 HTRTLNLYGAGDRSGGGSSVEVDYRGDEVQVATLLQLLAGRHNPATPRGKRLLTDENSQV 220

Query: 160 LLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQS 219
           LLY++GHGGD FLKFQD EE+ S DLADAV QMK + RF+E+L++ +TCQ +TL   + +
Sbjct: 221 LLYLSGHGGDGFLKFQDWEEISSVDLADAVAQMKAQRRFREMLLIAETCQGSTLLDAMAT 280

Query: 220 PGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEK--LNMYSNASLNSLFNSY 277
            GVL + SS   E+SYSHH D  +GV+V+DR+T+YTL FFEK   +  S+A+   L NSY
Sbjct: 281 AGVLGLASSGPKESSYSHHADGFLGVAVIDRWTYYTLQFFEKSVRDASSSATFEQLMNSY 340

Query: 278 NPSMLLSTAYYRMDLYERPLNEVPVTNFFGSVMNTIHTDSAY 319
           +   LLSTA  R +L+ RPL E  +T FF +  +   T   Y
Sbjct: 341 SRKQLLSTASVRTELFGRPLGETKLTEFFATASSLHATHGLY 382
>ref|NP_502076.1| Peptidase C13 family [Caenorhabditis elegans]
 sp|P49048|GPI8_CAEEL Potential GPI-anchor transamidase (GPI transamidase)
 pir||T24525 hypothetical protein T05E11.6 - Caenorhabditis elegans
 emb|CAA92977.1| Hypothetical protein T05E11.6 [Caenorhabditis elegans]
          Length = 322

 Score =  292 bits (741), Expect = 8e-78
 Identities = 145/286 (50%), Positives = 198/286 (68%), Gaps = 3/286 (1%)

Query: 25  MLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERI 84
           +   F    S+  S     H NNWAVLVCTS+FWFNYRH++N L+LY ++KRLGIPD  I
Sbjct: 19  IFFGFRFERSSGLSEKVTGHTNNWAVLVCTSKFWFNYRHVSNVLALYHSIKRLGIPDSNI 78

Query: 85  ILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESA 144
           I+MLA+D+ CN RN  P  V+       NLYG +VEVDYRG EVTVE+F+RVLTGRH  A
Sbjct: 79  IMMLAEDVPCNSRNPRPGTVY-AARAGTNLYGSDVEVDYRGEEVTVESFIRVLTGRHHPA 137

Query: 145 VPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIM 204
            PRSKRLL+D  S++L+Y+TGHGGD F+KFQDSEEL + DLA A++ M E +R+ E+L++
Sbjct: 138 TPRSKRLLTDHQSNVLIYLTGHGGDSFMKFQDSEELTNVDLAYAIQTMFEDNRYHEMLVI 197

Query: 205 VDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEK--L 262
            D+C++A+++  + SP VL++ SS+  E SYS+ +D+DIGV V+DR+T YT+ F  K   
Sbjct: 198 ADSCRSASMYEWIDSPNVLSLSSSLTHEESYSYDVDTDIGVYVIDRYTHYTVNFLTKEVK 257

Query: 263 NMYSNASLNSLFNSYNPSMLLSTAYYRMDLYERPLNEVPVTNFFGS 308
            + S+A++    +S      LS    R D Y + +  V VT+FFGS
Sbjct: 258 ALNSSANMQDYIDSCPARKCLSNTGVRKDHYPKDVKRVRVTDFFGS 303
>emb|CAC67556.1| Gpi8 transamidase [Trypanosoma brucei]
 emb|CAD29114.1| GPI anchor transamidase subunit [Trypanosoma brucei brucei]
          Length = 319

 Score =  206 bits (519), Expect = 9e-52
 Identities = 99/237 (41%), Positives = 152/237 (63%), Gaps = 2/237 (0%)

Query: 19  LLPALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLG 78
           +LP LL L+A    + AA    G    N WAV++ +SR++FN RH  N L++Y   ++ G
Sbjct: 1   MLPMLLWLVANLFLAPAAEGFHGMNKTNTWAVILSSSRYFFNLRHTTNALAMYHLCRKHG 60

Query: 79  IPDERIILMLADDMACNPRNNYPAQVFN--NENHQLNLYGDNVEVDYRGYEVTVENFLRV 136
           + D+ I++ L+D  AC+PR   PA ++    +  Q NLYG N+ VDY  Y+V V  FL V
Sbjct: 61  MDDDHILVFLSDSYACDPRKPNPATIYGAPAQAEQPNLYGCNIRVDYASYDVGVRRFLGV 120

Query: 137 LTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKH 196
           L GR++   P S+RL +DE S+I++Y  GH  ++F KFQDSE + S D+AD +  M E+ 
Sbjct: 121 LQGRYDENTPPSRRLDTDENSNIIIYAAGHSAEKFFKFQDSEFMSSTDIADTLMMMWEQR 180

Query: 197 RFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTF 253
           R+++L+ +VDTC+A +L  ++++P V+ + SS    +SYSHHLD   G +V+ R+TF
Sbjct: 181 RYRKLVFLVDTCRALSLCLEIKAPNVVCLASSEAHLDSYSHHLDPPSGFTVITRWTF 237
>dbj|BAC32653.1| unnamed protein product [Mus musculus]
          Length = 442

 Score =  193 bits (486), Expect = 7e-48
 Identities = 99/156 (63%), Positives = 115/156 (73%), Gaps = 7/156 (4%)

Query: 16  LVLLLPALLMLLAFSTS-------SSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTL 68
           L L +  L  L   S            A     + H NNWAVLVCTSRFWFNYRH+ANTL
Sbjct: 7   LTLRVATLAALALLSLGSSAAGHIEDQAEQFFRSGHTNNWAVLVCTSRFWFNYRHVANTL 66

Query: 69  SLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEV 128
           S+YR+VKRLGIPD  I+LMLADDMACN RN  PA VF+++N +LN+YGD+VEVDYR YEV
Sbjct: 67  SVYRSVKRLGIPDSHIVLMLADDMACNARNPKPATVFSHKNMELNVYGDDVEVDYRSYEV 126

Query: 129 TVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMT 164
           TVENFLRVLTGR   + PRSKRLLSD+ S+IL+YMT
Sbjct: 127 TVENFLRVLTGRVPPSTPRSKRLLSDDRSNILIYMT 162
 Score =  146 bits (366), Expect = 8e-34
 Identities = 68/144 (47%), Positives = 99/144 (68%)

Query: 166 HGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTI 225
           HGG+ FLKFQDSEE+ + +LADA +QM +K R+ ELL ++DTCQ A+++ +  SP ++ +
Sbjct: 211 HGGNGFLKFQDSEEITNIELADAFEQMWQKRRYNELLFIIDTCQGASMYERFYSPNIMAL 270

Query: 226 GSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEKLNMYSNASLNSLFNSYNPSMLLST 285
            SS  GE+S SH  D  IGV ++DR+TFY L F E++N  S  ++N LF     S+ +ST
Sbjct: 271 ASSQVGEDSLSHQPDPAIGVHLMDRYTFYVLEFLEEINPASQTNMNDLFQVCPKSLCVST 330

Query: 286 AYYRMDLYERPLNEVPVTNFFGSV 309
             +R DL++R    V +T+FFGSV
Sbjct: 331 PGHRTDLFQRDPKNVLITDFFGSV 354
>emb|CAB55340.1| GPI:protein transamidase [Leishmania mexicana]
          Length = 349

 Score =  184 bits (464), Expect = 2e-45
 Identities = 92/246 (37%), Positives = 150/246 (60%), Gaps = 8/246 (3%)

Query: 11  PSRALLVLLLPALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSL 70
           P+R +   L+    ++L  + ++SA   + G   +NNWAV+V +SR+ FNYRH AN L++
Sbjct: 11  PTRCIATALIVFAFLVLTAAAAASAPLGATGKGQSNNWAVIVSSSRYLFNYRHTANALTM 70

Query: 71  YRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN--------NENHQLNLYGDNVEVD 122
           Y  +++ GI D+ I+L L+D  AC+PRN YPA++F+        +    +NLYG + +VD
Sbjct: 71  YHLLRQHGIDDDHILLFLSDSFACDPRNVYPAEIFSQPPGAHDADGRASMNLYGCSAQVD 130

Query: 123 YRGYEVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQS 182
           Y G +V V  FL VL GR++   P ++RLLSD  S+I++Y+ GHG   + KFQD+E L S
Sbjct: 131 YAGSDVDVRRFLSVLQGRYDENTPPTRRLLSDNTSNIIIYVAGHGAKSYFKFQDTEFLSS 190

Query: 183 HDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIGSSMKGENSYSHHLDSD 242
            D+++ +  M ++ R+  ++ + DTC A  L   +++P V+ + +S     SYS   D  
Sbjct: 191 SDISETLTMMHQQRRYGRVVFLADTCHAIALCEHVEAPNVVCLAASDAESESYSCQYDEQ 250

Query: 243 IGVSVV 248
           +G  +V
Sbjct: 251 LGTHMV 256
>gb|AAL29895.1| GPI8 transamidase [Paramecium tetraurelia]
          Length = 309

 Score =  140 bits (350), Expect = 6e-32
 Identities = 67/209 (32%), Positives = 120/209 (57%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           N  +++ TS+FWFNYR   N+L +Y+ +K   I D++I LM+ +D ACN +NN P     
Sbjct: 19  NQYIILSTSKFWFNYRQAINSLMIYQQLKEWRINDDQISLMIPEDTACNRKNNVPGVACA 78

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTGH 166
            +  +      NV  D++  +V ++ ++ V+  ++    P+S+RL   +   +L++M GH
Sbjct: 79  QDGQREPNLHKNVNWDFKRNDVNIKYWIDVMRNKYNRYTPQSRRLTLSKEQKLLMFMNGH 138

Query: 167 GGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGVLTIG 226
           GGD + K QD+  L   ++    K+M+    ++E  ++ D+C A TLF  +++  ++ +G
Sbjct: 139 GGDGYTKMQDTTYLLDFEMEKITKEMEFLQLYQEAFLISDSCGAITLFETVKAQNMILLG 198

Query: 227 SSMKGENSYSHHLDSDIGVSVVDRFTFYT 255
           SS  GE +YSH   S + +S  D+F+  T
Sbjct: 199 SSSLGEKAYSHGRCSILSISKTDKFSLTT 227
>ref|NP_701158.1| GPI8p transamidase [Plasmodium falciparum 3D7]
 emb|CAB96076.1| GPI8p transamidase [Plasmodium falciparum]
 gb|AAN35882.1|AE014840_30 GPI8p transamidase [Plasmodium falciparum 3D7]
          Length = 493

 Score =  116 bits (288), Expect = 1e-24
 Identities = 80/244 (32%), Positives = 132/244 (53%), Gaps = 25/244 (10%)

Query: 44  HN--NNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLG-IPDERIILMLADDMACNPRNNY 100
           HN  NN  +L+ TSR +FNYRH  N L  Y+ +K  G   D+ I+LM+  D AC+ RN  
Sbjct: 59  HNYMNNNVILLSTSRHYFNYRHTTNLLIAYKYLKYFGDTMDKNILLMIPFDQACDCRNIR 118

Query: 101 PAQVF----------NNEN--HQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRS 148
             Q+F          N E     +NLY +N+ +DY+   V  E   RVL  R+++  P+ 
Sbjct: 119 EGQIFREYELFPSSHNKETKIENINLY-ENLNIDYKNNNVRDEQIRRVLRHRYDAFTPKK 177

Query: 149 KRLLSDEGS--HILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVD 206
            RL ++  +  ++ LYMTGHGG  FLK Q+   + S +    ++++  K+ +K + +++D
Sbjct: 178 NRLYNNGNNEKNLFLYMTGHGGVNFLKIQEFNIISSSEFNIYIQELLIKNFYKYIFVIID 237

Query: 207 TCQAATLFSQL-------QSPGVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFF 259
           TCQ  + +  +       +   +  + SS + ENSYS    S + VS VDRFT++   + 
Sbjct: 238 TCQGYSFYDDILNFVYKKKINNIFFLSSSKRNENSYSLFSSSYLSVSTVDRFTYHFFNYL 297

Query: 260 EKLN 263
           ++++
Sbjct: 298 QQIH 301
>gb|AAF73260.1|AF154349_1 legumain [Rattus norvegicus]
          Length = 435

 Score =  114 bits (283), Expect = 4e-24
 Identities = 67/199 (33%), Positives = 106/199 (52%), Gaps = 6/199 (3%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           +W V+V  S  W+NYRH A+    Y+ + R GIPDE+II+M+ DD+A N  N  P  V N
Sbjct: 31  HWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANNEENPTPGVVIN 90

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPR--SKRLLSDEGSHILLYMT 164
             N   ++Y   V  DY G +VT ENFL VL G  E+   +   K L S    H+ +Y T
Sbjct: 91  RPNGT-DVY-KGVPKDYTGEDVTPENFLAVLRGDEEAVKGKGSGKVLKSGPRDHVFVYFT 148

Query: 165 GHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSP-GVL 223
            HG    L F + E+L   DL   ++ M E   +++++  ++ C++ ++ + L     V 
Sbjct: 149 DHGATGILVFPN-EDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDIDVY 207

Query: 224 TIGSSMKGENSYSHHLDSD 242
              ++   E+SY+ + D +
Sbjct: 208 ATTAANPNESSYACYYDEE 226
>ref|NP_071562.1| protease, cysteine, 1 (legumain) [Rattus norvegicus]
 sp|Q9R0J8|LGMN_RAT Legumain precursor (Asparaginyl endopeptidase) (Protease, cysteine
           1)
 dbj|BAA84750.1| legumain [Rattus norvegicus]
          Length = 435

 Score =  114 bits (283), Expect = 4e-24
 Identities = 67/199 (33%), Positives = 106/199 (52%), Gaps = 6/199 (3%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           +W V+V  S  W+NYRH A+    Y+ + R GIPDE+II+M+ DD+A N  N  P  V N
Sbjct: 31  HWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANNEENPTPGVVIN 90

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPR--SKRLLSDEGSHILLYMT 164
             N   ++Y   V  DY G +VT ENFL VL G  E+   +   K L S    H+ +Y T
Sbjct: 91  RPNGT-DVY-KGVPKDYTGEDVTPENFLAVLRGDEEAVKGKGSGKVLKSGPRDHVFVYFT 148

Query: 165 GHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSP-GVL 223
            HG    L F + E+L   DL   ++ M E   +++++  ++ C++ ++ + L     V 
Sbjct: 149 DHGATGILVFPN-EDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDIDVY 207

Query: 224 TIGSSMKGENSYSHHLDSD 242
              ++   E+SY+ + D +
Sbjct: 208 ATTAANPNESSYACYYDEE 226
>ref|NP_035305.1| legumain; protease, cysteine, 1; preprolegumain; expressed sequence
           AU022324 [Mus musculus]
 sp|O89017|LGMN_MOUSE Legumain precursor (Asparaginyl endopeptidase) (Protease, cysteine
           1)
 emb|CAA04439.1| legumain [Mus musculus]
 gb|AAF21659.1|AF044266_1 preprolegumain; cysteine Protease [Mus musculus]
          Length = 435

 Score =  112 bits (278), Expect = 2e-23
 Identities = 67/209 (32%), Positives = 111/209 (53%), Gaps = 6/209 (2%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           +W V+V  S  W+NYRH A+    Y+ + R GIPDE+II+M+ DD+A +  N  P  V N
Sbjct: 31  HWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIIVMMYDDIANSEENPTPGVVIN 90

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPR--SKRLLSDEGSHILLYMT 164
             N   ++Y   V  DY G +VT ENFL VL G  E+   +   K L S    H+ +Y T
Sbjct: 91  RPNGT-DVY-KGVLKDYTGEDVTPENFLAVLRGDAEAVKGKGSGKVLKSGPRDHVFIYFT 148

Query: 165 GHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSP-GVL 223
            HG    L F + ++L   DL   ++ M E   +++++  ++ C++ ++ + L     V 
Sbjct: 149 DHGATGILVFPN-DDLHVKDLNKTIRYMYEHKMYQKMVFYIEACESGSMMNHLPDDINVY 207

Query: 224 TIGSSMKGENSYSHHLDSDIGVSVVDRFT 252
              ++   E+SY+ + D + G  + D ++
Sbjct: 208 ATTAANPKESSYACYYDEERGTYLGDWYS 236
>emb|CAB71158.1| asparaginyl endopeptidase [Schistosoma mansoni]
          Length = 429

 Score =  111 bits (276), Expect = 3e-23
 Identities = 68/220 (30%), Positives = 114/220 (50%), Gaps = 10/220 (4%)

Query: 24  LMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDER 83
           ++L+     ++   S      NN WAVLV  S  + NYRH A+    Y  ++  GI  E 
Sbjct: 14  ILLVKCQLDTNYEVSDETVSDNNKWAVLVAGSNGYPNYRHQADVCHAYHVLRSKGIKPEH 73

Query: 84  IILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHES 143
           II M+ DD+A N  N +P ++FN+ NH+ + Y + V +DYRG +V  + FL+VL G   +
Sbjct: 74  IITMMYDDIAYNLMNPFPGKLFNDYNHK-DWY-EGVVIDYRGKKVNSKTFLKVLKGDKSA 131

Query: 144 AVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLI 203
                K L S +   + +Y T HG    + F D +EL +      +K +    R+ +L+I
Sbjct: 132 G---GKVLKSGKNDDVFIYFTDHGAPGLIAFPD-DELYAKQFMSTLKYLHSHKRYSKLVI 187

Query: 204 MVDTCQAATLFSQLQSPGVLTIGSSMKG---ENSYSHHLD 240
            ++ C++ ++F ++  P  L+I ++      E+SY    D
Sbjct: 188 YIEACESGSMFQRIL-PSNLSIYATTAASPTESSYGTFCD 226
>dbj|BAB69947.1| legumain [Bos taurus]
          Length = 433

 Score =  110 bits (272), Expect = 9e-23
 Identities = 67/197 (34%), Positives = 106/197 (53%), Gaps = 6/197 (3%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           +W V+V  S  W+NYRH A+    Y+ V R GIPDE+II+M+ DD+A +  N  P  V N
Sbjct: 29  HWVVIVAGSNGWYNYRHQADACHAYQIVHRNGIPDEQIIVMMYDDIANSEDNPTPGIVIN 88

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHES--AVPRSKRLLSDEGSHILLYMT 164
             N   ++Y   V  DY G +VT +NFL VL G  E+   V   K L S    H+ +Y T
Sbjct: 89  RPNGS-DVY-QGVLKDYTGEDVTPKNFLAVLRGDAEAVKGVGSGKVLKSGPRDHVFVYFT 146

Query: 165 GHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSP-GVL 223
            HG    L F + E+L   DL + ++ M E   +++++  ++ C++ ++ + L     V 
Sbjct: 147 DHGATGILVFPN-EDLHVKDLNETIRYMYEHKMYQKMVFYIEACESGSMMNHLPPDINVY 205

Query: 224 TIGSSMKGENSYSHHLD 240
              ++   E+SY+ + D
Sbjct: 206 ATTAANPRESSYACYYD 222
>dbj|BAA09530.1| cysteine protease [Homo sapiens]
          Length = 433

 Score =  109 bits (271), Expect = 1e-22
 Identities = 64/197 (32%), Positives = 107/197 (53%), Gaps = 6/197 (3%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           +WAV+V  S  W+NYRH A+    Y+ + R GIPDE+I++M+ DD+A +  N  P  V N
Sbjct: 29  HWAVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVIN 88

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHES--AVPRSKRLLSDEGSHILLYMT 164
             N   ++Y   V  DY G +VT +NFL VL G  E+   +   K L S    H+ +Y T
Sbjct: 89  RPNGT-DVY-QGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146

Query: 165 GHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQL-QSPGVL 223
            HG    L F + E+L   DL + +  M +   +++++  ++ C++ ++ + L  +  V 
Sbjct: 147 DHGSTGILVFPN-EDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205

Query: 224 TIGSSMKGENSYSHHLD 240
              ++   E+SY+ + D
Sbjct: 206 ATTAANPRESSYACYYD 222
>ref|NP_005597.2| legumain; protease, cysteine, 1 (legumain) [Homo sapiens]
 gb|AAH03061.1|AAH03061 protease, cysteine, 1 (legumain) [Homo sapiens]
          Length = 433

 Score =  108 bits (267), Expect = 3e-22
 Identities = 63/197 (31%), Positives = 106/197 (52%), Gaps = 6/197 (3%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           +W V+V  S  W+NYRH A+    Y+ + R GIPDE+I++M+ DD+A +  N  P  V N
Sbjct: 29  HWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVIN 88

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHES--AVPRSKRLLSDEGSHILLYMT 164
             N   ++Y   V  DY G +VT +NFL VL G  E+   +   K L S    H+ +Y T
Sbjct: 89  RPNGT-DVY-QGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146

Query: 165 GHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQL-QSPGVL 223
            HG    L F + E+L   DL + +  M +   +++++  ++ C++ ++ + L  +  V 
Sbjct: 147 DHGSTGILVFPN-EDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205

Query: 224 TIGSSMKGENSYSHHLD 240
              ++   E+SY+ + D
Sbjct: 206 ATTAANPRESSYACYYD 222
>sp|Q99538|LGMN_HUMAN Legumain precursor (Asparaginyl endopeptidase) (Protease, cysteine
           1)
 emb|CAA70989.1| legumain [Homo sapiens]
          Length = 433

 Score =  108 bits (267), Expect = 3e-22
 Identities = 63/197 (31%), Positives = 106/197 (52%), Gaps = 6/197 (3%)

Query: 47  NWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFN 106
           +W V+V  S  W+NYRH A+    Y+ + R GIPDE+I++M+ DD+A +  N  P  V N
Sbjct: 29  HWVVIVAGSNGWYNYRHQADACHAYQIIHRNGIPDEQIVVMMYDDIAYSEDNPTPGIVIN 88

Query: 107 NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHES--AVPRSKRLLSDEGSHILLYMT 164
             N   ++Y   V  DY G +VT +NFL VL G  E+   +   K L S    H+ +Y T
Sbjct: 89  RPNGT-DVY-QGVPKDYTGEDVTPQNFLAVLRGDAEAVKGIGSGKVLKSGPQDHVFIYFT 146

Query: 165 GHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQL-QSPGVL 223
            HG    L F + E+L   DL + +  M +   +++++  ++ C++ ++ + L  +  V 
Sbjct: 147 DHGSTGILVFPN-EDLHVKDLNETIHYMYKHKMYRKMVFYIEACESGSMMNHLPDNINVY 205

Query: 224 TIGSSMKGENSYSHHLD 240
              ++   E+SY+ + D
Sbjct: 206 ATTAANPRESSYACYYD 222
>sp|P09841|HGLB_SCHMA Hemoglobinase precursor (Antigen SM32)
 pir||A60145 hemoglobinase (EC 3.4.-.-) precursor - fluke (Schistosoma mansoni)
          Length = 429

 Score =  107 bits (265), Expect = 6e-22
 Identities = 61/194 (31%), Positives = 102/194 (52%), Gaps = 6/194 (3%)

Query: 24  LMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDER 83
           ++L+     ++   S      NN WAVLV  S  + NYRH A+    Y  ++  GI  E 
Sbjct: 14  ILLVKCQLDTNYEVSDETVSDNNKWAVLVAGSNGYPNYRHQADVCHAYHVLRSKGIKPEH 73

Query: 84  IILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHES 143
           II M+ DD+A N  N +P ++FN+ NH+ + Y + V +DYRG  V  + FL+VL G   +
Sbjct: 74  IITMMYDDIAYNLMNPFPGKLFNDYNHK-DWY-EGVVIDYRGKNVNSKTFLKVLKGDKSA 131

Query: 144 AVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLI 203
                K L S +   + +Y T HG    + F D +EL + +    +K +    R+ +L+I
Sbjct: 132 G---GKVLKSGKNDDVFIYFTDHGAPGLIAFPD-DELYAKEFMSTLKYLHSHKRYSKLVI 187

Query: 204 MVDTCQAATLFSQL 217
            ++  ++ ++F Q+
Sbjct: 188 YIEANESGSMFQQI 201
>dbj|BAA90621.1| Similar to Phaseolus vulgaris Moldavian encoding
           asparagine-specific endopeptidase precursor (Z99956)
           [Oryza sativa (japonica cultivar-group)]
          Length = 452

 Score =  106 bits (263), Expect = 9e-22
 Identities = 61/199 (30%), Positives = 104/199 (51%), Gaps = 7/199 (3%)

Query: 48  WAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNN 107
           WA+L+  S+ + NYRH A+    Y+ +K+ G+ D+ I++M+ DD+A NP N +   + N 
Sbjct: 42  WALLIAGSKGYENYRHQADVCHAYQIMKKGGLKDQNIVVMMYDDIAYNPENPHKGVIINK 101

Query: 108 ENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHE--SAVPRSKRLLSDEGSHILLYMTG 165
            N   N+Y   V  DY G +V   NFL VL G+    +     K + S    HI +Y + 
Sbjct: 102 PNGP-NVYA-GVPKDYNGNDVNKNNFLAVLLGKKSALTGAGSGKVISSGPNDHIFVYYSD 159

Query: 166 HGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSP---GV 222
           HG   ++       L ++DL+ A+K       +K L++ V+ C++ ++F     P   GV
Sbjct: 160 HGSPGYVCMPSGGNLHANDLSQALKNKNAAGAYKNLVVYVEACESGSMFEGQLLPSNIGV 219

Query: 223 LTIGSSMKGENSYSHHLDS 241
             + +S   ENS++ + D+
Sbjct: 220 YAMTASNATENSWATYCDT 238
>ref|NP_506137.1| Peptidase C13 family (53.2 kD) [Caenorhabditis elegans]
 pir||T19231 probable cysteine proteinase (EC 3.4.22.-) T28H10.3, precursor
           [similarity] - Caenorhabditis elegans
 emb|CAB01126.1| Hypothetical protein T28H10.3 [Caenorhabditis elegans]
 emb|CAA99935.1| Hypothetical protein T28H10.3 [Caenorhabditis elegans]
          Length = 462

 Score =  106 bits (263), Expect = 1e-21
 Identities = 69/240 (28%), Positives = 119/240 (48%), Gaps = 11/240 (4%)

Query: 14  ALLVLLLPALLMLLAFSTSSSAAASSPGAMHN-----NNWAVLVCTSRFWFNYRHMANTL 68
           ALL+ ++   L+  A        A+     H        + VLV  S  W+NYRH A+  
Sbjct: 5   ALLICIIVLFLVTEARYNPRKGLAAGRQRKHKYQDEGEAFVVLVAGSNGWYNYRHQADVA 64

Query: 69  SLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEV 128
             Y T++  GIP+E II M+ DD+A NP N Y  ++FN   H  +LY   +++DY+G  V
Sbjct: 65  HAYHTLRNHGIPEENIITMMYDDVANNPLNPYKGKLFNRP-HGKDLY-KGLKIDYKGASV 122

Query: 129 TVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLAD 187
           T ENFL VL G        + R+L +++   + +Y T HG    + F D   L    L D
Sbjct: 123 TPENFLNVLKGNASGIDGGNGRVLETNDNDRVFVYFTDHGAVGMISFPDG-ILTVKQLND 181

Query: 188 AVKQMKEKHRFKELLIMVDTCQAATLFSQL--QSPGVLTIGSSMKGENSYSHHLDSDIGV 245
            +  M +  ++ +L   ++ C++ ++F ++      +  I ++   E+S+    ++D+ +
Sbjct: 182 VLVWMHKNKKYSQLTFYLEACESGSMFEEVLRSDMDIYAISAANSHESSWGTFCENDMNL 241
>gb|AAA29895.1| hemoglobinase
          Length = 429

 Score =  103 bits (255), Expect = 8e-21
 Identities = 60/194 (30%), Positives = 102/194 (51%), Gaps = 6/194 (3%)

Query: 24  LMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDER 83
           ++L+     ++   S      NN WAVLV  S  + NYRH A+    Y  ++  GI  E 
Sbjct: 14  ILLVKCQLDTNYEVSDETVSDNNKWAVLVAGSNGYPNYRHQADVCHAYHVLRSKGIKPEH 73

Query: 84  IILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHES 143
           II M+ DD+A N  N +  ++FN+ NH+ + Y + V +DYRG +V  + FL+VL G   +
Sbjct: 74  IITMMYDDIAYNLMNPFLGKLFNDYNHK-DWY-EGVVIDYRGKKVNSKTFLKVLKGDKSA 131

Query: 144 AVPRSKRLLSDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLI 203
                K L S +   + +Y T HG    + F D +EL + +    +K +    R+ +L+I
Sbjct: 132 G---GKVLKSGKNDDVFIYFTDHGAPGLIAFPD-DELYAKEFMSTLKYLHSHKRYSKLVI 187

Query: 204 MVDTCQAATLFSQL 217
            ++  ++ ++F Q+
Sbjct: 188 YIEANESGSMFQQI 201
>sp|P42665|HGLB_SCHJA Hemoglobinase precursor (Antigen Sj32)
 pir||S31908 hemoglobinase - fluke (Schistosoma japonicum)
 emb|CAA50304.1| hemoglobinase [Schistosoma japonicum]
          Length = 423

 Score =  103 bits (255), Expect = 8e-21
 Identities = 59/197 (29%), Positives = 102/197 (50%), Gaps = 8/197 (4%)

Query: 46  NNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVF 105
           + WAVLV  S  + NYRH A+    Y  +   G+  E II  + DD+A N  N +P ++F
Sbjct: 30  HKWAVLVAGSNGFENYRHQADVCHAYHVLLSKGVKPEHIITFMYDDIAHNKENPFPGKIF 89

Query: 106 NNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLLSDEGSHILLYMTG 165
           N+  H+   Y   V +DY+G +V  + FL+VL G   +     K L S +   + +Y T 
Sbjct: 90  NDYRHK--DYYKGVVIDYKGKKVNPKTFLQVLKGDKRAG---GKVLKSGKNDDVFIYFTD 144

Query: 166 HGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQL--QSPGVL 223
           HG    L F D ++L +    + +K +++  R+ +L+I V+ C++ ++F+ L      + 
Sbjct: 145 HGAPGILAFPD-DDLHAKPFINTLKYLRQHRRYSKLVIYVEACESGSMFAGLLPTDINIY 203

Query: 224 TIGSSMKGENSYSHHLD 240
              ++   E+SY+   D
Sbjct: 204 ATTAARPDESSYATFCD 220
>emb|CAB51545.1| vacuolar processing enzyme [Lycopersicon esculentum]
          Length = 460

 Score =  103 bits (255), Expect = 9e-21
 Identities = 54/176 (30%), Positives = 93/176 (52%), Gaps = 3/176 (1%)

Query: 48  WAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNN 107
           WAVLV  S+ W+NYRH AN    Y+ +K+ G+ DE II+ + DD+A NP N  P  + NN
Sbjct: 40  WAVLVAGSKEWYNYRHQANLCHAYQLLKKGGLKDEHIIVFMYDDIANNPENPRPGVIINN 99

Query: 108 ENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYMTGH 166
             H  ++Y   V  DY G +   +NF  V+ G   +    S +++ S    +I +Y T H
Sbjct: 100 P-HGHDVY-KGVPKDYTGKDCNAQNFYSVILGNKSALTGGSGKVVNSGPNDYIFIYYTDH 157

Query: 167 GGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGV 222
           G    +   +   + + DL + +K+      +K+++  ++ C + ++F+ L   G+
Sbjct: 158 GAPGLVGMPEDPPVYAIDLNEVLKKKHASRTYKKMVFYLEACDSGSMFADLLDEGL 213
>gb|EAA15187.1| GPI8p transamidase-related [Plasmodium yoelii yoelii]
          Length = 244

 Score =  103 bits (254), Expect = 1e-20
 Identities = 59/177 (33%), Positives = 99/177 (55%), Gaps = 14/177 (7%)

Query: 46  NNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLG-IPDERIILMLADDMACNPRNNYPAQV 104
           N+  + + TSR +FNYRH AN L  Y+ +K+ G I D+ I+LM+  D ACN RN     +
Sbjct: 65  NSNVIALSTSRHYFNYRHTANLLIAYKYLKKNGDIMDKNILLMIPFDQACNCRNIIEGTI 124

Query: 105 FN----------NENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLLSD 154
           F           N+N + NLY + + +DY+   +  E   +V+  R+ S  P + RL ++
Sbjct: 125 FKNYEKLPNEYINKNMKENLY-NKLNIDYKNDNINDEQLKKVIRHRNNSFTPYNNRLYTN 183

Query: 155 E--GSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQ 209
           E    ++ +Y+TGHGG  FLK Q+   + S +    ++++  K  +K + +++DTCQ
Sbjct: 184 EYKKKNLFIYITGHGGINFLKIQEFSIISSSEFNLYIQELLIKKIYKNIFVIIDTCQ 240
>dbj|BAC54829.1| vacuolar processing enzyme-2 [Nicotiana tabacum]
          Length = 484

 Score =  101 bits (250), Expect = 3e-20
 Identities = 62/198 (31%), Positives = 101/198 (50%), Gaps = 5/198 (2%)

Query: 48  WAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNN 107
           WAVLV  SR ++NYRH A+    Y+ +K+ G+ DE II+ + DD+A N  N  P  + N+
Sbjct: 50  WAVLVAGSRGYWNYRHQADVCHAYQLLKKGGLKDENIIVFMYDDIAHNFENPRPGVIINS 109

Query: 108 ENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYMTGH 166
            N   ++Y   V  DY G+ VT  NFL V+ G   +    S +++ S    HI ++ + H
Sbjct: 110 PNGD-DVY-KGVPKDYTGHHVTANNFLAVILGNKAALSGGSGKVVESGPNDHIFIFYSDH 167

Query: 167 GGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPG--VLT 224
           GG   L       L + DL D +K+      +K L+  ++ C++ ++F  L   G  +  
Sbjct: 168 GGPGVLGMPSGPYLYADDLIDVLKRKHASGTYKSLVFYIEACESGSIFEGLLPEGLNIYA 227

Query: 225 IGSSMKGENSYSHHLDSD 242
             +S   E+S+  +   D
Sbjct: 228 TTASNAEEDSWGTYCPGD 245
>ref|NP_180165.1| putative vacuolar processing enzyme; protein id: At2g25940.1,
           supported by cDNA: gi_16604313, supported by cDNA:
           gi_19699181 [Arabidopsis thaliana]
 sp|P49047|VPEA_ARATH Vacuolar processing enzyme, alpha-isozyme precursor (Alpha-VPE)
 pir||T02629 vacuolar processing enzyme (EC 3.4.22.-) isozyme alpha precursor -
           Arabidopsis thaliana
 gb|AAC31241.1| putative vacuolar processing enzyme [Arabidopsis thaliana]
 dbj|BAA09614.2| alpha-VPE [Arabidopsis thaliana]
 gb|AAL24163.1| At2g25940/F17H15.3 [Arabidopsis thaliana]
 gb|AAL90957.1| At2g25940/F17H15.3 [Arabidopsis thaliana]
 gb|AAM15043.1| putative vacuolar processing enzyme [Arabidopsis thaliana]
          Length = 478

 Score =  100 bits (248), Expect = 5e-20
 Identities = 57/179 (31%), Positives = 97/179 (53%), Gaps = 3/179 (1%)

Query: 45  NNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQV 104
           +  WAVLV  S  ++NYRH A+    Y+ +K+ G+ +E I++ + DD+A N  N  P  +
Sbjct: 42  STKWAVLVAGSSGYWNYRHQADVCHAYQLLKKGGVKEENIVVFMYDDIAKNEENPRPGVI 101

Query: 105 FNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYM 163
            N+ N + ++Y + V  DY G EV V+N L V+ G   +    S +++ S    HI +Y 
Sbjct: 102 INSPNGE-DVY-NGVPKDYTGDEVNVDNLLAVILGNKTALKGGSGKVVDSGPNDHIFIYY 159

Query: 164 TGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGV 222
           + HGG   L    S  L ++DL D +K+      +K L+  ++ C++ ++F  L   G+
Sbjct: 160 SDHGGPGVLGMPTSPNLYANDLNDVLKKKYASGTYKSLVFYLEACESGSIFEGLLPEGL 218
>gb|AAF21773.1|AF067448_1 hemoglobinase-type cysteine proteinase [Caenorhabditis elegans]
          Length = 187

 Score = 98.8 bits (243), Expect = 2e-19
 Identities = 56/168 (33%), Positives = 91/168 (53%), Gaps = 4/168 (2%)

Query: 51  LVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENH 110
           LV  S  W+NYRH A+    Y T++  GIP+E II M+ DD+A NP N Y  ++FN   H
Sbjct: 1   LVAGSNGWYNYRHQADVAHAYHTLRNHGIPEENIITMMYDDVANNPLNPYKGKLFNRP-H 59

Query: 111 QLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYMTGHGGD 169
             +LY   +++DY+G   T ENFL VL G        + R+L +++   + +Y T HG  
Sbjct: 60  GKDLY-KGLKIDYKGASETPENFLNVLKGNASGIDGGNGRVLETNDNDRVFVYFTDHGAV 118

Query: 170 EFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQL 217
             + F D   L    L D +  M +  ++ +L   ++ C++ ++F ++
Sbjct: 119 GMISFPDG-ILTVKQLNDVLVWMHKNKKYSQLTFYLEACESGSMFEEV 165
>emb|CAB64544.1| legumain-like protease [Zea mays]
          Length = 486

 Score = 96.9 bits (238), Expect = 9e-19
 Identities = 57/189 (30%), Positives = 95/189 (50%), Gaps = 3/189 (1%)

Query: 30  STSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLA 89
           S  ++AA  +        WAVL+  S  ++NYRH A+    Y+ +K+ G+ DE II+ + 
Sbjct: 33  SQRAAAADETDDGAVGTRWAVLIAGSSGYYNYRHQADICHAYQIMKKGGLKDENIIVFMY 92

Query: 90  DDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSK 149
           DD+A +P N  P  + N+     ++Y   V  DY G +V V+NF  VL G   +    S 
Sbjct: 93  DDIAHSPENPRPGVIINHPQGG-DVYA-GVPKDYTGRDVNVDNFFAVLLGNKTALRGGSG 150

Query: 150 RLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTC 208
           +++ S    HI ++ + HGG   L       L   DL D +K+      +K L+  ++ C
Sbjct: 151 KVVDSGPDDHIFVFYSDHGGPGVLGMPTYPYLYGDDLVDVLKKKHAAGTYKSLVFYLEAC 210

Query: 209 QAATLFSQL 217
           ++ ++F  L
Sbjct: 211 ESGSIFEGL 219
>emb|CAC18099.1| putative legumain [Zea mays]
          Length = 486

 Score = 95.7 bits (235), Expect = 2e-18
 Identities = 57/189 (30%), Positives = 95/189 (50%), Gaps = 3/189 (1%)

Query: 30  STSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLA 89
           S  ++AA  +        WAVL+  S  ++NYRH A+    Y+ +K+ G+ DE II+ + 
Sbjct: 33  SQRAAAADETDDGDVGTRWAVLIAGSSGYYNYRHQADICHAYQIMKKGGLKDENIIVFMY 92

Query: 90  DDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSK 149
           DD+A +P N  P  + N+     ++Y   V  DY G +V V+NF  VL G   +    S 
Sbjct: 93  DDIAHSPENPRPGVIINHPQGG-DVYA-GVPKDYTGRDVNVDNFFAVLLGNKTALRGGSG 150

Query: 150 RLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTC 208
           +++ S    HI ++ + HGG   L       L   DL D +K+      +K L+  ++ C
Sbjct: 151 KVVDSGPNDHIFVFYSDHGGPGVLGMPTYPYLYGDDLVDVLKKKHAAGTYKSLVFYLEAC 210

Query: 209 QAATLFSQL 217
           ++ ++F  L
Sbjct: 211 ESGSIFEGL 219
>dbj|BAC54827.1| vacuolar processing enzyme-1a [Nicotiana tabacum]
          Length = 490

 Score = 95.3 bits (234), Expect = 2e-18
 Identities = 64/212 (30%), Positives = 107/212 (50%), Gaps = 13/212 (6%)

Query: 17  VLLLPALLMLLAFSTSSSAAASSPGAMHNNN-----WAVLVCTSRFWFNYRHMANTLSLY 71
           VL LP+       S    A  S+ G  H+++     WA+L+  S  ++NYRH A+    Y
Sbjct: 26  VLKLPS-----EVSRFFGADKSNVGDDHDDDSVGTRWAILLAGSNGYWNYRHQADICHAY 80

Query: 72  RTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVE 131
           + +K+ G+ DE I++ + DD+A N  N  P  + N+  H  ++Y   V  DY G +VTV 
Sbjct: 81  QLLKKGGLKDENIVVFMYDDIANNEENPRPGVIINSP-HGEDVY-KGVPKDYTGDDVTVN 138

Query: 132 NFLRVLTGRHESAVPRSKRLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVK 190
           NF   L G   +    S +++ S    HIL++ + HGG   L       L ++DL D +K
Sbjct: 139 NFFAALLGNKTALSGGSGKVVNSGPNDHILIFYSDHGGPGVLGMPTDPYLYANDLIDVLK 198

Query: 191 QMKEKHRFKELLIMVDTCQAATLFSQLQSPGV 222
           +      +K L+  ++ C++ ++F  L   G+
Sbjct: 199 KKHASGTYKSLVFYLEACESGSIFEGLLPEGL 230
>ref|NP_597033.1| putative PEPTIDASE [Encephalitozoon cuniculi]
 emb|CAD27081.1| putative PEPTIDASE [Encephalitozoon cuniculi]
          Length = 278

 Score = 93.7 bits (230), Expect = 6e-18
 Identities = 62/223 (27%), Positives = 115/223 (50%), Gaps = 21/223 (9%)

Query: 43  MHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPA 102
           M   N+A+L+ +SR ++NYRHMAN    Y  +++ G  D++I+++  ++   + RN+   
Sbjct: 21  MAARNYAILLNSSRGFYNYRHMANVYVFYNVLRQNGFEDDQILIVSYENQIQDIRNSDRG 80

Query: 103 QVFNNENHQLNLYGDNVEVDYRGYEVT---VENFLRVLTGRHESAVPRSKRLLSDEGSHI 159
            V+ +E+ +         + Y  +  T   +E  L  ++G +      +K   +DE S+I
Sbjct: 81  GVYIDEDSK---------IPYSAFSPTSNVLEELLNAISGNN------AKLKDADESSNI 125

Query: 160 LLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQS 219
            +Y+ GHG + FLKF +   +   DL   + ++    R  ++L+++DTCQA  L  +   
Sbjct: 126 FIYLNGHGNEAFLKFGNIHFMTRDDLMPRISKLAA--RVNKILLVIDTCQADALVDRSAL 183

Query: 220 P-GVLTIGSSMKGENSYSHHLDSDIGVSVVDRFTFYTLAFFEK 261
           P  VL + +S  G+ + S    S I  +V+D F ++    F K
Sbjct: 184 PRNVLVVATSKIGQPAISSFSSSLICANVIDNFPYFFFKRFGK 226
>dbj|BAC54830.1| vacuolar processing enzyme-3 [Nicotiana tabacum]
          Length = 481

 Score = 93.7 bits (230), Expect = 7e-18
 Identities = 54/176 (30%), Positives = 94/176 (52%), Gaps = 3/176 (1%)

Query: 48  WAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNN 107
           WAVL+  S  ++NYRH A+    Y+ +++ G+ DE II+ + DD+A N  N     + N+
Sbjct: 47  WAVLLAGSNGYWNYRHQADVCHAYQLLRKGGLKDENIIMFMYDDIAYNEENPRQGVIINS 106

Query: 108 ENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYMTGH 166
              + ++Y   V  DY G +V V+NFL VL G   +    S +++ S    HI ++ + H
Sbjct: 107 PAGE-DVY-KGVPKDYTGDDVNVDNFLAVLLGNKTALTGGSGKVVDSGPNDHIFIFYSDH 164

Query: 167 GGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGV 222
           GG   L    +  L + DL D +K+      +K L++ ++ C++ ++F  L   G+
Sbjct: 165 GGPGVLGMPTNPYLYASDLIDVLKKKHASGTYKSLVLYIEACESGSIFEGLLPKGL 220
>sp|P49043|VPE_CITSI Vacuolar processing enzyme precursor (VPE)
 pir||S51117 cysteine proteinase (EC 3.4.22.-) precursor [similarity] - sweet
           orange
 emb|CAA87720.1| cystein proteinase (by similarity) [Citrus sinensis]
 prf||2208463A vascular processing protease
          Length = 494

 Score = 93.3 bits (229), Expect = 9e-18
 Identities = 62/219 (28%), Positives = 106/219 (48%), Gaps = 5/219 (2%)

Query: 7   GIPGPSRALL--VLLLPALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHM 64
           GI   SR +   +L LP+       +    A  +         WAVL+  S  ++NYRH 
Sbjct: 18  GIADGSRDIAGDILKLPSEAYRFFHNGGGGAKVNDDDDSVGTRWAVLLAGSNGFWNYRHQ 77

Query: 65  ANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYR 124
           A+    Y+ +++ G+ DE II+ + DD+A N  N  P  + N+  H  ++Y   V  DY 
Sbjct: 78  ADICHAYQLLRKGGLKDENIIVFMYDDIAFNEENPRPGVIINHP-HGDDVY-KGVPKDYT 135

Query: 125 GYEVTVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSH 183
           G +VTVE F  V+ G   +    S +++ S    HI ++ + HGG   L    S  + + 
Sbjct: 136 GEDVTVEKFFAVVLGNKTALTGGSGKVVDSGPNDHIFIFYSDHGGPGVLGMPTSRYIYAD 195

Query: 184 DLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGV 222
           +L D +K+      +K L+  ++ C++ ++F  L   G+
Sbjct: 196 ELIDVLKKKHASGNYKSLVFYLEACESGSIFEGLLLEGL 234
>dbj|BAC54828.1| vacuolar processing enzyme-1b [Nicotiana tabacum]
          Length = 489

 Score = 92.6 bits (227), Expect = 2e-17
 Identities = 60/207 (28%), Positives = 102/207 (48%), Gaps = 4/207 (1%)

Query: 17  VLLLPALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKR 76
           VL LP+ +    F    S A           WA+L+  S  ++NYRH A+    Y+ +K+
Sbjct: 26  VLKLPSEVSRF-FGADESNAGDHDDDSVGTRWAILLAGSNGYWNYRHQADICHAYQLLKK 84

Query: 77  LGIPDERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRV 136
            G+ DE I++ + DD+A N  N     + N+  H  ++Y   V  DY G +VTV+NF  V
Sbjct: 85  GGLKDENIVVFMYDDIANNEENPRRGVIINSP-HGEDVY-KGVPKDYTGDDVTVDNFFAV 142

Query: 137 LTGRHESAVPRSKRLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEK 195
           + G   +    S +++ S    HI ++ + HGG   L       L ++DL D +K+    
Sbjct: 143 ILGNKTALSGGSGKVVNSGPNDHIFIFYSDHGGPGVLGMPTDPYLYANDLIDVLKKKHAS 202

Query: 196 HRFKELLIMVDTCQAATLFSQLQSPGV 222
             +K L+  ++ C++ ++F  L   G+
Sbjct: 203 GTYKSLVFYLEACESGSIFEGLLPEGL 229
>emb|CAC18100.1| putative legumain [Zea mays]
          Length = 485

 Score = 91.4 bits (224), Expect = 3e-17
 Identities = 58/198 (29%), Positives = 97/198 (48%), Gaps = 3/198 (1%)

Query: 21  PALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIP 80
           P L   +   +  +AA  +        WAVL+  S  ++NYRH A+    Y+ +K+ G+ 
Sbjct: 23  PRLEPTIRLPSERAAADETDDDAVGTRWAVLIAGSNGYYNYRHQADICHAYQIMKKGGLK 82

Query: 81  DERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGR 140
           DE I++ + DD+A +P N  P  + N+     ++Y   V  DY G EV V+NF  VL G 
Sbjct: 83  DENIVVFMYDDIAHSPENPRPGVIINHPQGG-DVYA-GVPKDYTGREVNVDNFFAVLLGN 140

Query: 141 HESAVPRSKRLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFK 199
             +    S +++ S    HI ++ + HGG   L       L   DL D +K+      +K
Sbjct: 141 KTALRGGSGKVVDSGPNDHIFVFYSDHGGPGVLGMPTYPYLYGDDLVDVLKKKHAAGTYK 200

Query: 200 ELLIMVDTCQAATLFSQL 217
            L+  ++ C++ ++F  L
Sbjct: 201 SLVFYLEACESGSIFEGL 218
>gb|AAD04883.1| C13 endopeptidase NP1 precursor [Zea mays]
          Length = 485

 Score = 90.2 bits (221), Expect = 8e-17
 Identities = 57/198 (28%), Positives = 97/198 (48%), Gaps = 3/198 (1%)

Query: 21  PALLMLLAFSTSSSAAASSPGAMHNNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIP 80
           P L   +   +  +AA  +        WAVL+  S  ++NYRH A+    Y+ +K+ G+ 
Sbjct: 23  PRLEPTIRLPSERAAADETDDDAVGTRWAVLIAGSNGYYNYRHQADICHAYQIMKKGGLK 82

Query: 81  DERIILMLADDMACNPRNNYPAQVFNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGR 140
           DE I++ + DD+A +P N  P  + N+     ++Y   V  DY G +V V+NF  VL G 
Sbjct: 83  DENIVVFMYDDIAHSPENPRPGVIINHPQGG-DVYA-GVPKDYTGRDVNVDNFFAVLLGN 140

Query: 141 HESAVPRSKRLL-SDEGSHILLYMTGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFK 199
             +    S +++ S    HI ++ + HGG   L       L   DL D +K+      +K
Sbjct: 141 KTALRGGSGKVVDSGPNDHIFVFYSDHGGPGVLGMPTYPYLYGDDLVDVLKKKHAAGTYK 200

Query: 200 ELLIMVDTCQAATLFSQL 217
            L+  ++ C++ ++F  L
Sbjct: 201 SLVFYLEACESGSIFEGL 218
>dbj|BAA84650.1| asparaginyl endopeptidase [Oryza sativa]
 dbj|BAB85400.1| asparaginyl endopeptidase [Oryza sativa (japonica cultivar-group)]
          Length = 501

 Score = 83.6 bits (204), Expect = 8e-15
 Identities = 71/239 (29%), Positives = 109/239 (44%), Gaps = 30/239 (12%)

Query: 12  SRALLVLLLPALLMLLAFSTSSSAAASSP---------------------------GAMH 44
           +RA L L+LP L  LL F+  ++ A + P                            A  
Sbjct: 3   ARARLRLVLPPLAALLLFAHLAAVAVARPRWEEEGSNLRLPSERAVAAGAAADDAAEAAE 62

Query: 45  NNNWAVLVCTSRFWFNYRHMANTLSLYRTVKRLGIPDERIILMLADDMACNPRNNYPAQV 104
              WAVL+  S  ++NYRH A+    Y+ +KR G+ DE II+ + DD+A NP N  P  +
Sbjct: 63  GTRWAVLIAGSNGYYNYRHQADVCHAYQIMKRGGLKDENIIVFMYDDIAHNPENPRPGVI 122

Query: 105 FNNENHQLNLYGDNVEVDYRGYEVTVENFLRVLTGRHESAVPRSKRLL-SDEGSHILLYM 163
            N+     ++Y   V  DY G EV V+N   VL G   +    S ++L S    HI ++ 
Sbjct: 123 INHPQGG-DVYA-GVPKDYTGKEVNVKNLFAVLLGNKTAVKGGSGKVLDSGPNDHIFIFY 180

Query: 164 TGHGGDEFLKFQDSEELQSHDLADAVKQMKEKHRFKELLIMVDTCQAATLFSQLQSPGV 222
           + HGG   L       L   DL D +K+      +K L+  ++ C++ ++F  L   G+
Sbjct: 181 SDHGGPGVLGMPTYPYLYGDDLVDVLKKKHAAGTYKSLVFYLEACESGSIFEGLLPNGI 239
CPU time:   110.12 user secs.	    2.05 sys. secs	  112.17 total secs.

  Database: nr
    Posted date:  Jan 18, 2003  1:23 PM
  Number of letters in database: 421,297,171
  Number of sequences in database:  1,315,992
  
Lambda     K      H
   0.319    0.134    0.387 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 326719702
Number of Sequences: 1315992
Number of extensions: 13326787
Number of successful extensions: 34885
Number of sequences better than 10.0: 99
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 34665
Number of HSP's gapped (non-prelim): 110
length of query: 404
length of database: 421,297,171
effective HSP length: 60
effective length of query: 344
effective length of database: 342,337,651
effective search space: 117764151944
effective search space used: 117764151944
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 75 (33.6 bits)