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GPI Anchor Biosynthesis Report: orf6.7409.prot (PIG-B family, Candida albicans)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (482 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 4

Distribution of 55 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 499 e-140
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 476 e-133
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 472 e-132
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 469 e-131
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 434 e-120
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 401 e-110
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 392 e-108
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 371 e-101
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 342 1e-92
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 325 1e-87
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 325 1e-87
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 323 5e-87
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 320 3e-86
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 319 6e-86
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 295 2e-78
emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus mus... 285 1e-75
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 277 2e-73
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 277 3e-73
gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melano... 275 1e-72
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 257 3e-67
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 255 1e-66
ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo ... 254 2e-66
emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-... 253 4e-66
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 243 5e-63
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 238 2e-61
ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans] ... 230 4e-59
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 228 2e-58
pir||T39659 cell wall biosynthesis protein N3265 homolog - fissi... 226 9e-58
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 224 2e-57
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 222 1e-56
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 221 2e-56
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 217 5e-55
pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans 212 7e-54
ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. ... 200 7e-50
gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan ... 195 1e-48
ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Sacch... 195 1e-48
ref|NP_488386.1| (NC_003272) hypothetical protein [Nostoc sp. PC... 192 1e-47
gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 190 6e-47
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 172 1e-41
gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protei... 156 7e-37
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 143 5e-33
dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharom... 122 2e-26
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 116 1e-24
pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans 108 2e-22
ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]... 103 8e-21
Alignments
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase -like protein [Arabidopsis
           thaliana]
 gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
          Length = 548

 Score =  499 bits (1273), Expect = e-140
 Identities = 148/522 (28%), Positives = 250/522 (47%), Gaps = 59/522 (11%)

Query: 7   LSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIH 66
            S  ++F F   FR+ N+  I+T+F  DE +Q+LE AH  ++GYGY+TWEWK+ +RS +H
Sbjct: 36  GSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLH 95

Query: 67  PLIYVLGYKLVG----DNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLML 122
           P+++   YKL+     D   ++  +P+++ ++ +AIG+  LYK         +A  +L  
Sbjct: 96  PMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFC 155

Query: 123 SLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGF----GFVSCIIRP 178
            + N F ++ + R+FSN LE V T++ L +WP  +  +  + ++  +      ++C IRP
Sbjct: 156 QMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRP 215

Query: 179 TNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINTA--LDYFYQKLTFPLYNFLEF 236
           T+ +IW+ +G+  L      +K++ L  + +  ++L  T       Y        NFL+F
Sbjct: 216 TSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKF 275

Query: 237 NVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL--KKNILLLTGLFY-IIGFSL 293
           N F  +   +YGT PW++Y  Q   +ML  + P  I G+   KN  L   + + +  +S+
Sbjct: 276 N-FLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSI 334

Query: 294 IQHKEFRFIYPIHPILLYFTARGY-------------------------VKFKPKFVLLG 328
           + HKEFRF+ P+ PI L F+   +                          K+ PK  L  
Sbjct: 335 LGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSV 394

Query: 329 IL---LNICIGLFFTNVHERGVID-LKYLATQQTP---TSVGFITPCHSTPWQSYFHNPN 381
                 NI + L+ +  H+RG  D + YL+ +       S+ F+ PCHSTP+ S  H   
Sbjct: 395 YFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHR-- 452

Query: 382 LDTNSWFLACEPPLHLNKPSMEEIRHYRDQSDQFYDAPESFLQTHLGKDLPKTEQLVVFE 441
            +    FL C P            +   D+SDQF   P  F              +V+F 
Sbjct: 453 -NIPMQFLDCTPSAE---------KGELDESDQFLVNPLGFASELARNWSEPPSHIVLFA 502

Query: 442 PLEPLMNDYL-GREYYECQRFYNSFFHWDSRRDGDIIVYCRN 482
             E  + D++    + E +RF+++ F  D      ++VY  N
Sbjct: 503 SEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVVYVVN 544
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
           GPI-anchor biosynthesis [Mus musculus]
 dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
          Length = 542

 Score =  476 bits (1215), Expect = e-133
 Identities = 151/497 (30%), Positives = 243/497 (48%), Gaps = 34/497 (6%)

Query: 7   LSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIH 66
             +  L  F    R+ N F ++T F  DE++Q+LE AH  V+ YGYLTWEW ++LR   +
Sbjct: 47  GENTYLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTY 106

Query: 67  PLIYVLGYKLV----GDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLML 122
           PLI+   YK++     D+   +   P++  AL++A+ +  LY  +   +++++A    + 
Sbjct: 107 PLIFASIYKVLHLLGKDSVQFLIWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLC 166

Query: 123 SLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNIL 182
            L + F WY  TR+ +N +E   T LAL ++P     + +         ++C++RPT ++
Sbjct: 167 QLCSWFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSVNSIKYSLLVALACVVRPTALI 226

Query: 183 IWIPLGIWLLISIRITLKWVALSFLEVV--LILLINTALDYFYQKLTFPLYNFLEFNVFY 240
            W+PL        +  L      FL V      L       F+ + T    NFL+FNV  
Sbjct: 227 PWVPLLFRHFYQEQRKLHLTLHHFLPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVL- 285

Query: 241 KNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL-----KKNILLLTGLFYIIGFSLIQ 295
           +NL  FYG+ PW++Y+ Q  P++L  +LP  I+G      + +ILLLT L+ ++ +S++ 
Sbjct: 286 QNLGTFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLG 345

Query: 296 HKEFRFIYPIHPILLYFTARGYVK---FKPKFVLLGILLNICIGLFFTNVHERGVIDLKY 352
           HKEFRFIYP+ P  + F          ++   +   +L N+ +  +   VH+RG +D+  
Sbjct: 346 HKEFRFIYPVLPFCMVFCGYSLAHLKTWRKAALSFLLLSNVPLAFYTGLVHQRGTLDVMN 405

Query: 353 LATQQTP-------TSVGFITPCHSTPWQSYFHNPNLDTNSWFLACEPPLHLNKPSMEEI 405
              +  P        SV  + PCHSTP+ S+ H P    +  FL C P L          
Sbjct: 406 HIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCP---LSMRFLQCPPDLTGKT------ 456

Query: 406 RHYRDQSDQFYDAPESFLQTHLGKDLPKTEQLVVFEPLEPLMNDYLGREYYE-CQRFYNS 464
             Y D++D FY  P  +LQ     +      LV F  LE  +N +L    YE    F+++
Sbjct: 457 -QYLDEADMFYLNPLRWLQQEFHSNASLPTHLVTFNVLEKEINTFLTSGNYERAATFFHT 515

Query: 465 FFHWDSRRDGDIIVYCR 481
            +    R    I VY R
Sbjct: 516 HWPE-RRTGSHIHVYER 531
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
          Length = 554

 Score =  472 bits (1204), Expect = e-132
 Identities = 150/497 (30%), Positives = 243/497 (48%), Gaps = 34/497 (6%)

Query: 7   LSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIH 66
             +  L  F    R+ N F ++T F  DE++Q+LE +HH V+ YGYLTWEW ++LRS  +
Sbjct: 58  GENIYLLLFTLALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTY 117

Query: 67  PLIYVLGYKLV----GDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLML 122
           PLI+   YK++     D+  L+   P++  AL++A+ +  LY  +   +++++A      
Sbjct: 118 PLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFC 177

Query: 123 SLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNIL 182
            L + F WY  TR+ +N +E V T++AL ++P     + +         ++ IIRPT ++
Sbjct: 178 QLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVI 237

Query: 183 IWIPLGIWLLISIRITLKWVALSFLEVV--LILLINTALDYFYQKLTFPLYNFLEFNVFY 240
           +W PL           L  +   FL V    + L       F+ + T   +NFL+FNV  
Sbjct: 238 LWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVL- 296

Query: 241 KNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL-----KKNILLLTGLFYIIGFSLIQ 295
           +NL  FYG+ PW++Y  Q  P++L  +LP  I+G      +  ILL+T L+ ++ +S++ 
Sbjct: 297 QNLGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLS 356

Query: 296 HKEFRFIYPIHPILLYFTARGYVK---FKPKFVLLGILLNICIGLFFTNVHERGVIDLKY 352
           HKEFRFIYP+ P  + F          +K   +    L N+ + L+   VH+RG +D+  
Sbjct: 357 HKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMS 416

Query: 353 LATQQT-------PTSVGFITPCHSTPWQSYFHNPNLDTNSWFLACEPPLHLNKPSMEEI 405
              +           S+  + PCHSTP+ S+ H P       FL C P L          
Sbjct: 417 HIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCP---LPMRFLQCPPDLTGKS------ 467

Query: 406 RHYRDQSDQFYDAPESFLQTHLGKDLPKTEQLVVFEPLEPLMNDYLGREYYE-CQRFYNS 464
            HY D++D FY  P ++       D      L+ F  LE  ++ +L    Y+    F+++
Sbjct: 468 -HYLDEADVFYLNPLNWSHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHT 526

Query: 465 FFHWDSRRDGDIIVYCR 481
                 R    I VY R
Sbjct: 527 HLPE-GRIGSHIYVYER 542
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
 pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
           (EC 2.4.1.130) PIGB - human
 dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
          Length = 554

 Score =  469 bits (1197), Expect = e-131
 Identities = 150/497 (30%), Positives = 243/497 (48%), Gaps = 34/497 (6%)

Query: 7   LSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIH 66
             +  L  F    R+ N F ++T F  DE++Q+LE +HH V+ YGYLTWEW ++LRS  +
Sbjct: 58  GENIYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTY 117

Query: 67  PLIYVLGYKLV----GDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLML 122
           PLI+   YK++     D+  L+   P++  AL++A+ +  LY  +   +++++A      
Sbjct: 118 PLIFASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFC 177

Query: 123 SLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNIL 182
            L + F WY  TR+ +N +E V T++AL ++P     + +         ++ IIRPT ++
Sbjct: 178 QLCSWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVI 237

Query: 183 IWIPLGIWLLISIRITLKWVALSFLEVV--LILLINTALDYFYQKLTFPLYNFLEFNVFY 240
           +W PL           L  +   FL V    + L       F+ + T   +NFL+FNV  
Sbjct: 238 LWTPLLFRHFCQEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVL- 296

Query: 241 KNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL-----KKNILLLTGLFYIIGFSLIQ 295
           +N   FYG+ PW++Y  Q  P++L  +LP  I+G      +  ILL+T L+ ++ +S++ 
Sbjct: 297 QNWGTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLS 356

Query: 296 HKEFRFIYPIHPILLYFTARGYVK---FKPKFVLLGILLNICIGLFFTNVHERGVIDLKY 352
           HKEFRFIYP+ P  + F          +K   +    L N+ + L+   VH+RG +D+  
Sbjct: 357 HKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALSFLFLSNLFLALYTGLVHQRGTLDVMS 416

Query: 353 LATQQT-------PTSVGFITPCHSTPWQSYFHNPNLDTNSWFLACEPPLHLNKPSMEEI 405
              +           S+  + PCHSTP+ S+ H P       FL C P L          
Sbjct: 417 HIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCP---LPMRFLQCPPDLTGKS------ 467

Query: 406 RHYRDQSDQFYDAPESFLQTHLGKDLPKTEQLVVFEPLEPLMNDYLGREYYE-CQRFYNS 464
            HY D++D FY  P ++L      D      L+ F  LE  ++ +L    Y+    F+++
Sbjct: 468 -HYLDEADVFYLNPLNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHT 526

Query: 465 FFHWDSRRDGDIIVYCR 481
                 R    I VY R
Sbjct: 527 HLPE-GRIGSHIYVYER 542
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein - Arabidopsis
           thaliana
 emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein [Arabidopsis
           thaliana]
          Length = 498

 Score =  434 bits (1107), Expect = e-120
 Identities = 132/498 (26%), Positives = 222/498 (44%), Gaps = 82/498 (16%)

Query: 7   LSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIH 66
            S  ++F F   FR+ N+  I+T+F  DE +Q+LE AH  ++GYGY+TWEWK+ +RS +H
Sbjct: 36  GSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLH 95

Query: 67  PLIYVLGYKLVG----DNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLML 122
           P+++   YKL+     D   ++  +P+++ ++ +AIG+  LYK         +A      
Sbjct: 96  PMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW---- 151

Query: 123 SLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGF----GFVSCIIRP 178
                                V T++ L +WP  +  +  + ++  +      ++C IRP
Sbjct: 152 -------------------STVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRP 192

Query: 179 TNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINTA--LDYFYQKLTFPLYNFLEF 236
           T+ +IW+ +G+  L      +K++ L  + +  ++L  T       Y        NFL+F
Sbjct: 193 TSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKF 252

Query: 237 NVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL--KKNILLLTGLFY-IIGFSL 293
           N F  +   +YGT PW++Y  Q   +ML  + P  I G+   KN  L   + + +  +S+
Sbjct: 253 N-FLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSI 311

Query: 294 IQHKEFRFIYPIHPILLYFTARGY-------------------------VKFKPKFVLLG 328
           + HKEFRF+ P+ PI L F+   +                          K+ PK  L  
Sbjct: 312 LGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSV 371

Query: 329 IL---LNICIGLFFTNVHERGVID-LKYLATQQTP---TSVGFITPCHSTPWQSYFHNPN 381
                 NI + L+ +  H+RG  D + YL+ +       S+ F+ PCHSTP+ S  H   
Sbjct: 372 YFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHR-- 429

Query: 382 LDTNSWFLACEPPLHLNKPSMEEIRHYRDQSDQFYDAPESFLQTHLGKDLPKTEQLVVFE 441
            +    FL C P            +   D+SDQF   P  F              +V+F 
Sbjct: 430 -NIPMQFLDCTPSAE---------KGELDESDQFLVNPLGFASELARNWSEPPSHIVLFA 479

Query: 442 PLEPLMNDYL-GREYYEC 458
             E  + D++    + E 
Sbjct: 480 SEETKLRDFMIQHSFKEA 497
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
          Length = 512

 Score =  401 bits (1020), Expect = e-110
 Identities = 136/514 (26%), Positives = 243/514 (46%), Gaps = 85/514 (16%)

Query: 8   SSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIHP 67
               +F  I   RLA+ F ++T++  DE++Q+LE AH   +GYGYLTWEW Q +RS ++P
Sbjct: 2   KLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYP 61

Query: 68  LIYVLGYKLVG----DNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLS 123
           L+    YK++     D+  L+ + P+                         +    L L 
Sbjct: 62  LLIAGLYKILALLQLDSAHLLVVLPR-------------------------IRKWALFLI 96

Query: 124 LFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILI 183
           L   F +Y  +R+ +N LE   T +AL ++PW     G     L    + C +RPT  +I
Sbjct: 97  LVPWFWFYTGSRTLANTLEASLTTIALSYFPWY----GESTAYLWPAAICCFLRPTAAVI 152

Query: 184 WIPLGIWLLISIR------ITLKWVALSFLEVVLILLINTALDYFYQKLTFPLYNFLEFN 237
           W+PL ++ L   R      I  ++V    + +++  L      Y++ +L    Y FL++N
Sbjct: 153 WLPLSLYHLRRSRQNVLELILKRFVL---IGLLVAGLGIAIDTYWHGQLIVTPYEFLKYN 209

Query: 238 VFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKN-----------ILLLTGLF 286
           +F  N+  FYG+ PW++Y    +P +L +     I+G+ +             LL+T   
Sbjct: 210 IF-NNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFL 268

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVL--------LGILLNICIGLF 338
            ++  S ++HKEFRF+ P+ P+ LY       ++  +           + ++ N+    +
Sbjct: 269 TLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWY 328

Query: 339 FTNVHERGVIDLK---------YLATQQTPTSVGFITPCHSTPWQSYFHNPNLDTNSWFL 389
            + VH++G I+L          Y   ++   ++ F+ PCHSTP+ S+ H    +    FL
Sbjct: 329 LSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQ---NVTMRFL 385

Query: 390 ACEPPLHLNKPSMEEIRHYRDQSDQFYDAPESFLQTHLGKD--LPKTEQLVVFEPLEPLM 447
            CEP       ++E+   Y+D++D+F++ P  ++ +H+           +V+F+PL   +
Sbjct: 386 TCEP-------NLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENI 438

Query: 448 NDYLGREYYECQRFYNSFFHWDSRRDGDIIVYCR 481
           + +L R Y    R  ++  +  SR    I+VY R
Sbjct: 439 SVFL-RNYRLLHRIEHA-ENRQSRTGRSILVYQR 470
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
 dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
          Length = 506

 Score =  392 bits (998), Expect = e-108
 Identities = 133/481 (27%), Positives = 234/481 (47%), Gaps = 49/481 (10%)

Query: 7   LSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIH 66
            S  ++ A    FR AN+  + T+F  DE +Q LE AH  V+GYG+LTWEWK+ LRS +H
Sbjct: 43  GSERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLH 102

Query: 67  PLIYVLGYKLVG----DNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLML 122
           P I+   YK++     D+   + ++P+++ ++ A+ G+  LYK   +  +  +A +  +L
Sbjct: 103 PFIFAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVL 162

Query: 123 SLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNIL 182
           ++   + W+V   S   N  +     A +  P ++K+      +L    ++C IRPT+ +
Sbjct: 163 TVTGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKM------ALLIAALACAIRPTSAI 216

Query: 183 IWIPLGIWLLISIRITLKWVALSFLEVVLILLINT--ALDYFYQKLTFPLYNFLEFNVFY 240
            W+ +G+   I ++   +++ L  + + + +L  T     + Y        NFL+FN+F 
Sbjct: 217 TWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFS 276

Query: 241 KNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL---KKNILLLTGLFYIIGFSLIQHK 297
                +YGT  +++Y  Q  P M+  +LP  I G+   ++  L    ++ ++ +S++ HK
Sbjct: 277 SGG-DYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAGLIVWVLVVYSILGHK 335

Query: 298 EFRFIYPIHPILLYFTA----------------RGYVKFKPKFVLLGILLNICIGLFFTN 341
           EFRF+ P+ P +  F+                 +G +      V+L IL N+ + L+ + 
Sbjct: 336 EFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSL 395

Query: 342 VHERGVID-LKYLATQQTP---TSVGFITPCHSTPWQSYFHNPNLDTNSWFLACEPPLHL 397
            H+RG  D + YL+ +       SV F+ PCHSTP+ S  H    +    FL C P    
Sbjct: 396 YHQRGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHY---NLPMRFLDCTP---- 448

Query: 398 NKPSMEEIRHYRDQSDQFYDAPESFLQTHLGKDLPKTEQLVVFEPLEPLMNDYLGREYYE 457
                 E +   D+SD+F   P  F+    G +L     +V+FE  E  +   L   + E
Sbjct: 449 -----SENKGTLDESDRFLMNPADFVGEVFG-NLSSFSHIVLFESEERHVKLLLRNSFQE 502

Query: 458 C 458
            
Sbjct: 503 V 503
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
           [Schizosaccharomyces pombe]
          Length = 506

 Score =  371 bits (944), Expect = e-101
 Identities = 166/521 (31%), Positives = 254/521 (47%), Gaps = 65/521 (12%)

Query: 9   SYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIHPL 68
               +  I +FR  N+  ++TFFQ DEF+Q+LE AHHF++ YG+LTWEW   +RSA+HPL
Sbjct: 2   RIWFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHPL 61

Query: 69  IYVLGYKLVG----DNTTLVCI-SPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLS 123
           I+   Y+++     D++  V   +PK++    AAI +Y  YKF +V    K A  TL  S
Sbjct: 62  IFAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKTANWTLACS 121

Query: 124 LFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWY--------ISLGF---GFV 172
           L +  N YV  R+FSN+LE   T +   ++ +  K   S            LGF      
Sbjct: 122 LVSIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAF 181

Query: 173 SCIIRPTNILIWIPLGIWL-------------LISIRITLKW--------VALSFLEVVL 211
           +C IRPTNIL+WI   ++                ++    ++        +   F+  V 
Sbjct: 182 ACFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVS 241

Query: 212 ILLINTA-LDYFYQKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPL 270
           + L+N       Y +  FP+ +F +FNV    LS  YG   W++Y+ QA+PL+   +LP 
Sbjct: 242 LFLVNIIADRILYGRFVFPIISFFQFNV-TSGLSSLYGLNAWHYYLSQALPLICGGFLPF 300

Query: 271 MIYGLKKNILLLTGLFYIIGFSLIQHKEFRFIYPIHPILL-----YFTARGYVKFKPKFV 325
           ++  +       T L     +SLI HKE RF+YPI PILL     +F++    K   +F 
Sbjct: 301 VLLTMDL-QTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFFSSFSSWKRAARFF 359

Query: 326 LLGILLNICIGLFFTNVHERGVID-LKYLATQQTPTSVG-FITPCHSTPWQSYFHNPNLD 383
            L  L +  +  F    H+ GV++ +  + +       G  + PCH+TPWQS+ H+P  +
Sbjct: 360 FLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKNQTGLILAPCHTTPWQSHIHSPFAE 419

Query: 384 TNSWFLACEPPLHLNKPSMEEIRHYRDQSDQFYDAPESFLQTHLGKDLPKTEQLVVFEPL 443
               FL CEP     KP         D++D+FY+   +FL     K+    + L+ FE  
Sbjct: 420 NGWKFLTCEP---FEKPF--------DETDRFYENMPTFLDKI--KEW--PDYLIFFEER 464

Query: 444 EPLMNDYLGR---EYYECQRFYNSFFHWDSRRDGDIIVYCR 481
              +  YL     +Y E QR+YNS       R G ++VY +
Sbjct: 465 FYSLYSYLDSRGLKYEEVQRYYNSLIPESRERAGALLVYKK 505
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
           could be the target of the GPI synthesis inhibitor,
           YW3548; Most likely an alpha 1,2 mannosyltransferase
           utilized for the addition of the third mannose onto the
           GPI core structure.; Gpi1>
 sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
 pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
 emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
          Length = 616

 Score =  342 bits (869), Expect = 1e-92
 Identities = 154/512 (30%), Positives = 244/512 (47%), Gaps = 95/512 (18%)

Query: 39  ALEPAHHFVYGYGYLTWEWKQQLRSAIHPLIYVLGYKLVGDNTTLVCISPKVINALIAAI 98
           + + A         L ++     RS  +                 V  +PK++ A++A+I
Sbjct: 114 SWQVAEDL----KRLPFDVT---RSFEY---------------YGVIYAPKIVMAVLASI 151

Query: 99  GEYNLYKFIIVYDSE------------------KLAWITLMLSLFNPFNWYVITRSFSNN 140
           GEY + +F+                        ++    L+LSL N FN + ITR+F N+
Sbjct: 152 GEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFALLLSLTNFFNCFFITRTFINS 211

Query: 141 LEMVFTVLALRFWPWNKK---INGSWYISLGFGFVSCIIRPTNILIWIPLGIWLLISIRI 197
            EM+ T +AL +W W         S+  SL F F++C+ RP++ LIW+   I L++++  
Sbjct: 212 FEMILTSIALYYWDWTGGQMIKESSFTKSLIFAFLACLQRPSSGLIWVIPSISLILNLVG 271

Query: 198 TLKWVALSFL-------EVVLILLINTALDYFYQKLTFPLYNFLEFNVFYKNLSIFYGTA 250
             ++  L            ++         YFY+K+TFP + FL+FN F   LS FYG A
Sbjct: 272 KKQYHLLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPFFRFLKFN-FTTPLSKFYGVA 330

Query: 251 PWYFYIFQAIPLMLMLYLPLMIYGLKKN---------------ILLLTGLFYIIGFSLIQ 295
           PW+F+ FQ++P++L   +P   +GL                   + LT L  ++ +S + 
Sbjct: 331 PWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLP 390

Query: 296 HKEFRFIYPIHPILLYFTARGYVKFKPKF----------VLLGILLNICIGLFFTNVHER 345
           HKEFRFI+P+ P+ +  ++ G ++    +          + L   +++ I L     HE 
Sbjct: 391 HKEFRFIFPLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHES 450

Query: 346 GVID-LKYLATQQTPTSVGFITPCHSTPWQSYFHNPNLDTNSWFLACEPPLHL--NKPSM 402
           G I+ +K+L  +    S+GFI PCHSTP QSY H  ++  + W + C PPLHL  +  + 
Sbjct: 451 GSIEVMKFLHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQ-DLWSITCNPPLHLLGDPEAY 509

Query: 403 EEIRHYRDQSDQFYDAPESFLQTHLG----KDLPK---------TEQLVVFEPLE-PLMN 448
            ++  Y D+SD  YD   +F+  +      KDL              LVVFE +E   + 
Sbjct: 510 SKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENAFLK 569

Query: 449 DYL-GREYYECQRFYNSFFHWDSRRDGDIIVY 479
           D+L    Y E  RF+NS  HWDSRR GDII+Y
Sbjct: 570 DFLKDSSYIEYNRFFNSLAHWDSRRSGDIIIY 601
 Score = 73.0 bits (178), Expect = 1e-11
 Identities = 35/72 (48%), Positives = 47/72 (64%), Gaps = 3/72 (4%)

Query: 11 KLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIHPLIY 70
           +F     FR+ N+    TFFQADEF+QALEPAH   + YG LTWEWK  +RS + P+I+
Sbjct: 19 WVF---LAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYGELTWEWKFGVRSYLFPMIF 75

Query: 71 VLGYKLVGDNTT 82
           L Y+LV  ++ 
Sbjct: 76 ELTYRLVSLSSI 87
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
           musculus]
          Length = 611

 Score =  325 bits (826), Expect = 1e-87
 Identities = 72/342 (21%), Positives = 140/342 (40%), Gaps = 31/342 (9%)

Query: 13  FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIHPLIY 70
           F  +   RL  +         DE F   EP H+ +YG G+ TWE+     +RS  + L++
Sbjct: 62  FKCLLSARLCAALL-SNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLH 120

Query: 71  ----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
                   +++  N  LV    + + A ++ + E   YK +       ++ + L   + +
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLS 180

Query: 127 PFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILIWIP 186
              +   +    ++  M  T++A+  W  +K    +    LG    + +  P +  + +P
Sbjct: 181 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDK----TPIAVLGVAAGAILGWPFSAALGLP 236

Query: 187 LGIWLLISIRITLKWVALSFLEVVLILL-INTALDYFYQKLTFPLYNFLEFNVFYKNLSI 245
           +   LL        ++  S + + L L+ +     Y+Y KL     N + +NVF  +   
Sbjct: 237 IAFDLLARKHRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVLYNVFTSHGPD 296

Query: 246 FYGTAPWYFYIFQA---------IPLMLMLYLPLMIYGLKK----------NILLLTGLF 286
            YGT PWYFY+            + L+++    LM Y L++           + L     
Sbjct: 297 LYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYI 356

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLG 328
           + I F +  HKE RF++P++P++    A      +  +  + 
Sbjct: 357 WFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVF 398
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
          Length = 611

 Score =  325 bits (825), Expect = 1e-87
 Identities = 73/342 (21%), Positives = 141/342 (40%), Gaps = 31/342 (9%)

Query: 13  FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIHPLIY 70
           F  +   RL  +         DE F   EP H+ +YG G+ TWE+     +RS  + L++
Sbjct: 62  FKCLLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120

Query: 71  ----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
                   +++  N  LV    + + A ++ I E   YK +       ++ + L   + +
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180

Query: 127 PFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILIWIP 186
              +   +    ++  M  T++A+  W  +K    +    LG    + +  P +  + +P
Sbjct: 181 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDK----TSIAVLGVAAGAILGWPFSAALGLP 236

Query: 187 LGIWLLISIRITLKWVALSFLEVVLILL-INTALDYFYQKLTFPLYNFLEFNVFYKNLSI 245
           +   LL+       +   S + ++L L+ +     Y+Y KL     N + +NVF  +   
Sbjct: 237 IAFDLLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPD 296

Query: 246 FYGTAPWYFYIFQA---------IPLMLMLYLPLMIYGLKK----------NILLLTGLF 286
            YGT PWYFY+            + L+++    LM Y L++           + L     
Sbjct: 297 LYGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYI 356

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLG 328
           + I F +  HKE RF++P++P++    A      +  +  + 
Sbjct: 357 WFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVF 398
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
          Length = 611

 Score =  323 bits (821), Expect = 5e-87
 Identities = 74/342 (21%), Positives = 142/342 (40%), Gaps = 31/342 (9%)

Query: 13  FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIHPLIY 70
           F  +   RL  +         DE F   EP H+ +YG G+ TWE+     +RS  + L++
Sbjct: 62  FKCLLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120

Query: 71  ----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
                   +++  N  LV    + + A ++ I E   YK +       ++ + L   + +
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180

Query: 127 PFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILIWIP 186
              +   +    ++  M  T++A+  W  +K    +    LG    + +  P +  + +P
Sbjct: 181 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDK----TSIAVLGVAAGAILGWPFSAALGLP 236

Query: 187 LGIWLLISIRITLKWVALSFLEVVLILL-INTALDYFYQKLTFPLYNFLEFNVFYKNLSI 245
           +   LL+       +   S + ++L L+ +     Y+Y KL     N + +NVF  +   
Sbjct: 237 IAFDLLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPD 296

Query: 246 FYGTAPWYFYIF---------QAIPLMLMLYLPLMIYGLKK----------NILLLTGLF 286
            YGT PWYFY+           A+ L+++    LM Y L++           + L     
Sbjct: 297 LYGTEPWYFYLIKGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYI 356

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLG 328
           + I F +  HKE RF++P++P++    A      +  +  + 
Sbjct: 357 WFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVF 398
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
          Length = 618

 Score =  320 bits (814), Expect = 3e-86
 Identities = 74/339 (21%), Positives = 141/339 (40%), Gaps = 31/339 (9%)

Query: 13  FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIHPLIY 70
           F  +   RL  +         DE F   EP H+ +YG G+ TWE+     +RS  + L++
Sbjct: 62  FKCLLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120

Query: 71  ----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
                   +++  N  LV    + + A ++ I E   YK +       ++ + L   + +
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180

Query: 127 PFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILIWIP 186
              +   +    ++  M  T++A+  W  +K    +    LG    + +  P +  + +P
Sbjct: 181 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDK----TSIAVLGVAAGAILGWPFSAALGLP 236

Query: 187 LGIWLLISIRITLKWVALSFLEVVLILL-INTALDYFYQKLTFPLYNFLEFNVFYKNLSI 245
           +   LL+       +   S + ++L L+ +     Y+Y KL     N + +NVF  +   
Sbjct: 237 IAFDLLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPD 296

Query: 246 FYGTAPWYFYIFQA---------IPLMLMLYLPLMIYGLKK----------NILLLTGLF 286
            YGT PWYFY+            + L+++    LM Y L++           + L     
Sbjct: 297 LYGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYI 356

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFV 325
           + I F +  HKE RF++P++P++    A      +  F+
Sbjct: 357 WFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQHSFL 395
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
           mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
 dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
          Length = 618

 Score =  319 bits (811), Expect = 6e-86
 Identities = 73/339 (21%), Positives = 141/339 (41%), Gaps = 31/339 (9%)

Query: 13  FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIHPLIY 70
           F  +   RL  +         DE F   EP H+ +YG G+ TWE+     +RS  + L++
Sbjct: 62  FKCLLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120

Query: 71  ----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
                   +++  N  LV    + + A ++ I E   YK +       ++ + L   + +
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180

Query: 127 PFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILIWIP 186
              +   +    ++  M  T++A+  W  +K    +    LG    + +  P +  + +P
Sbjct: 181 TGMFCSSSAFLPSSFCMYTTLIAMTGWYMDK----TSIAVLGVAAGAILGWPFSAALGLP 236

Query: 187 LGIWLLISIRITLKWVALSFLEVVLILL-INTALDYFYQKLTFPLYNFLEFNVFYKNLSI 245
           +   LL+       +   S + ++L L+ +     Y+Y KL     N + +N+F  +   
Sbjct: 237 IAFDLLVMKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNIFTPHGPD 296

Query: 246 FYGTAPWYFYIFQA---------IPLMLMLYLPLMIYGLKK----------NILLLTGLF 286
            YGT PWYFY+            + L+++    LM Y L++           + L     
Sbjct: 297 LYGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYI 356

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFV 325
           + I F +  HKE RF++P++P++    A      +  F+
Sbjct: 357 WFIIFFIQPHKEERFLFPVYPLICLCGAVALSALQHSFL 395
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
          Length = 558

 Score =  295 bits (748), Expect = 2e-78
 Identities = 104/461 (22%), Positives = 186/461 (39%), Gaps = 81/461 (17%)

Query: 9   SYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIHPL 68
            + L +  FI+RL     I T    DE++Q+ E A++ V+G G+L WEW+  LRS + P 
Sbjct: 2   PWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPA 61

Query: 69  IYVLGYKLVG----DNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSE----------- 113
           +  L + L+     D T  V  +P+V+ AL+  + + +++      D             
Sbjct: 62  VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121

Query: 114 --------------------------KLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTV 147
                                      +++  L+LSL N +  Y   R + N +E +  +
Sbjct: 122 TRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVL 181

Query: 148 LALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILIWIPLGIWLLIS-------IRITLK 200
           L L+           +   L    ++  IR T+ ++  PL    L +       IR   +
Sbjct: 182 LTLQQ--------RRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFR 233

Query: 201 WVALSFLEV-VLILLINTALDYFYQKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQA 259
            V    + +  ++  +      FY +       F  FNV + NLS F+G  PWYFY+   
Sbjct: 234 IVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLH-NLSRFFGEHPWYFYVGPV 292

Query: 260 I------PLMLMLYLPLMIY------GLKKNILLLTGL--FYIIGFSLIQHKEFRFIYPI 305
           +       ++  +  PL+++       + + +L + G+  + +  +SLI HKE RF++ +
Sbjct: 293 LVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVV 352

Query: 306 HPILLYFTARGYVKFKP------KFVLLGILLNICIGLFFTNVHERGVID-LKYLATQQT 358
            P+ L   A   V++        K   L +L NI +      V+ RG +D +  +     
Sbjct: 353 IPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPR 412

Query: 359 PTSVGFITPCHSTPWQSYFHNPNLDTNSWFLACEPPLHLNK 399
              +  I  C++ P  SY H         F+ C   L    
Sbjct: 413 INRLDVIATCYTVPGYSYMHKKVNHLG--FVDCSIDLDEKT 451
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
          Length = 483

 Score =  285 bits (724), Expect = 1e-75
 Identities = 75/391 (19%), Positives = 142/391 (36%), Gaps = 44/391 (11%)

Query: 3   KSTVLSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVY------GYGYLTWE 56
           K +          + +        I  + + +E F  L+  H  +Y       Y +  + 
Sbjct: 4   KKSSGKRSWPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHHEF- 61

Query: 57  WKQQL--RSAIHPLIYVLG-------YKLVGDNTTLVCISPKVINALIAAIGEYNLYKFI 107
               +  R+ + PL+             L+  +     +  + +  L    G + L K +
Sbjct: 62  --PGVVPRTFLGPLVIAAFSSPVVYVLSLLEVSKFYSQLIVRGVLGLGVISGLWTLQKEV 119

Query: 108 IVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISL 167
                  +A +   +S       +  TR+  N L +   + AL  W   +     W + +
Sbjct: 120 RQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRR-----WALFV 174

Query: 168 GFGFVSCII-RPTNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINT--ALDYFYQ 224
                  I  R    ++     +  L   R+T+  V    +   L+ L  T     YF++
Sbjct: 175 WLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSYFWR 234

Query: 225 KLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLM---LYLPLMIYGLKKNILL 281
            L +P    L +N    N S  +GT+P  +Y + A+P  L    L++PL     +   L 
Sbjct: 235 YLVWPEGVVLGYNTVL-NKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYALA 293

Query: 282 LTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYV------KFKPKFVLLGILLNICI 335
           L  L ++  +SL+ HKE RFI    P+L    ARG         +  K   + +  +I +
Sbjct: 294 LPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILNKKSWPYKVRAMLVTGHILV 353

Query: 336 -------GLFFTNVHERGVIDLKYLATQQTP 359
                   L+ ++ +  G + ++ L     P
Sbjct: 354 NVAYTATSLYVSHFNYPGGVAMQQLHELVPP 384
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
 gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
 gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
          Length = 623

 Score =  277 bits (704), Expect = 2e-73
 Identities = 76/341 (22%), Positives = 133/341 (38%), Gaps = 31/341 (9%)

Query: 13  FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIHPLIY 70
           F      RL ++         DE F   EP H+ + G+G  TWE+     LRS  + L+ 
Sbjct: 77  FKTFVSARLCSAIW-AYIADCDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQ 135

Query: 71  ----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
                   KL   +  L+    + +     A+ E  +YK I       +  + L+  LF+
Sbjct: 136 GVPGYFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFS 195

Query: 127 PFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNILIWIP 186
              +   T    ++  M F   AL  W W +    + +++      + +  P   LI IP
Sbjct: 196 VGMFVSSTALLPSSFSMYFGCAALAAW-WQQNYCFAIFLT---AISALLGWPFAALIGIP 251

Query: 187 LGIWLLISIRITLKWVALSFLEVVLILLINT-ALDYFYQKLTFPLYNFLEFNVFYKNLSI 245
           L + +L+  R    +V  + +    + +        ++ KLTF   N + +NVF  +   
Sbjct: 252 LVLEMLLRQRDWKTFVQWTLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPN 311

Query: 246 FYGTAPWYFYIFQAIP-----LMLMLYLPLMI--------------YGLKKNILLLTGLF 286
            +GT P  +YI           +L L LP+M+                    I L     
Sbjct: 312 IFGTEPLSYYIINGFLNFNIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYL 371

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLL 327
           +++ F    HKE RF++PI+P++    A     ++  F  +
Sbjct: 372 WLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRM 412
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
           - fission yeast (Schizosaccharomyces pombe)
 emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
           [Schizosaccharomyces pombe]
          Length = 577

 Score =  277 bits (702), Expect = 3e-73
 Identities = 76/360 (21%), Positives = 140/360 (38%), Gaps = 32/360 (8%)

Query: 3   KSTVLSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--Q 60
           KS  +S    F+ + + RL ++ +       DE +   EP H+ +YGYG  TWE+     
Sbjct: 8   KSLSVSFVWTFSILAVLRLTSA-SFRVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPEYA 66

Query: 61  LRSAIHPLIYV---LGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAW 117
           +RS  +  ++       + +G +   V    + + A  +A  E NL   +    +  +A 
Sbjct: 67  IRSWFYIALHAVPGFLARGLGLSRLHVFYFIRGVLACFSAFCETNLILAVARNFNRAVAL 126

Query: 118 ITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIR 177
               +   N   W   T    ++  M    LAL           +  +       + I  
Sbjct: 127 HLTSVLFVNSGMWSASTSFLPSSFAMNMVTLALSAQLSPPSTKRTVKVVSFITIGAVIGW 186

Query: 178 PTNILIWIPLGIWLLIS-----IRITLKWVALSFLEVVLILLINTALDYFYQKLTFPLYN 232
           P +  + IP  +  L+        +  +W    F+ +++  +  T    FY ++ F  +N
Sbjct: 187 PFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQFVAWN 246

Query: 233 FLEFNVFYKN--LSIFYGTAPWYFYIFQAIPLMLMLYL-------PLMIYGLKKNILLL- 282
            +++NV  K+      YGT PW++Y    + L   + L       PL++     N + L 
Sbjct: 247 IVKYNVLAKDGRGPDIYGTEPWWYYFAN-LSLQHNIVLWFAMACGPLVLLAAFTNWINLD 305

Query: 283 ----------TGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLGILLN 332
                         ++  F +  HKE RF+YPI+P+L    A G        + +   +N
Sbjct: 306 SFLDLSSVISPFYIWLFIFIIQPHKEERFMYPIYPVLCLAAAIGLDMSLKLMIQILSSIN 365
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
 gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
          Length = 678

 Score =  275 bits (697), Expect = 1e-72
 Identities = 74/379 (19%), Positives = 154/379 (40%), Gaps = 46/379 (12%)

Query: 16  IFIFRLANSFAIETFF-QADEFFQALEPAHHFVY------GYGYLTWEWKQQL--RSAIH 66
           I IF  A +  + T F + +E F  L+  H  +Y       Y +  +     +  R+ I 
Sbjct: 3   ILIFVTAAAHLVYTPFTKVEESFN-LQAMHDILYLRNNFTQYDHHDY---PGVVPRTFIG 58

Query: 67  PL-------IYVLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWIT 119
           PL        +VL ++ +  N        +++ A   ++   +L + +      ++    
Sbjct: 59  PLVVSIISAPFVLLFETLSINKFWAQYVVRLVLAGAISVAWNSLRQAVTKIYGVEVRLWF 118

Query: 120 LMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPT 179
             +++      + +TR   N   +   + A+ +W  ++     + I  G   +  + R  
Sbjct: 119 TAITITQFHFMFYMTRPLPNIFALPIVLFAIAYWLRDQHK--PFIICSGISIL--VFRSE 174

Query: 180 NILIWIPLGIWLLISIRITLKWVALSFLEVVLILLI--NTALDYFYQKLTFPLYNFLEFN 237
             L    L +  L+  ++++  +    L   + +L        +F+++L +P    L +N
Sbjct: 175 LALFLGILLVVSLLRRKVSIDGLLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYN 234

Query: 238 VFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL----KKNILLLTGLFYIIGFSL 293
               N S  +GT+P+ +Y + A+P  +   L L+  G+    +   L+L+ L +++ +S+
Sbjct: 235 TVL-NKSSNWGTSPFLWYFYSALPRAMGASLVLVPIGVALEPRIRPLVLSALLFVLLYSI 293

Query: 294 IQHKEFRFIYPIHPILLYFTARGYVKF--------KPKFVLL----GILLNICIGLFF-- 339
           + HKE RFI  + P+L    A    +            F+ L     +LLN+ I LF   
Sbjct: 294 LPHKELRFIIYVFPVLNIAAACACQRIWMNSAKSTWHSFLALACGAHLLLNVFITLFLLV 353

Query: 340 -TNVHERGVIDLKYLATQQ 357
            +  +  G   L  L   +
Sbjct: 354 ISGTNYPGGAALSRLHRLE 372
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
          Length = 919

 Score =  257 bits (652), Expect = 3e-67
 Identities = 68/337 (20%), Positives = 136/337 (40%), Gaps = 25/337 (7%)

Query: 7   LSSYKLFAFIFI--FRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLR 62
                   FI +   R  ++ +       DE F   EP H+ +Y  G+ TWE+     LR
Sbjct: 391 GGLRWFLPFIALCYLRYMSATS-NIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALR 449

Query: 63  SAIHPLIYVLGYK----LVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWI 118
           S ++ L + L  +      GD+   V  + ++   L++A+ +  L   +     +++A  
Sbjct: 450 SYLYILFHELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATY 509

Query: 119 TLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRP 178
            + +       ++  T    ++  M    L+     + K         +G      +  P
Sbjct: 510 AVAMLCLTSGCFFASTSFLPSSFSMYAISLSSGLLLFEKYAMAVAVSVVGV----ILGWP 565

Query: 179 TNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINTALDYFYQKLTFPLYNFLEFNV 238
            +IL ++P+ I+ L+  R    ++A +   + L+ +      Y+Y++ T  + N L +NV
Sbjct: 566 FSILAFLPVVIYSLV-KRFKQAFIAGAVTTIFLLGVSLLVDYYYYKRWTSSVLNLLIYNV 624

Query: 239 FYKNLSIFYGTAPWYFYI---------FQAIPLMLMLYLPLMIYGLKKNILLL--TGLFY 287
                S  YGT    FYI            + ++ +   P++     + +L++      +
Sbjct: 625 LGGGESHLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW 684

Query: 288 IIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKF 324
           +   SL  HKE RF+YPI+P++    +         F
Sbjct: 685 LAFMSLQPHKEERFLYPIYPLICVSASAVIENIPELF 721
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
 sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
 pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
 emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
           (Swiss Prot accession number P38376)~cDNA EST yk549e12.3
           comes from this gene~cDNA EST yk618d6.3 comes from this
           gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
           yk618d6.5 comes from>
          Length = 653

 Score =  255 bits (646), Expect = 1e-66
 Identities = 70/366 (19%), Positives = 137/366 (37%), Gaps = 36/366 (9%)

Query: 8   SSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAI 65
           S   +F  +   R++ +         DE +   EP H F+YG G+ TWE+     +RS  
Sbjct: 52  SFGSVFKMLLSIRISGAIWG-IINDCDEVYNYWEPLHLFLYGEGFQTWEYSPVYAIRSYF 110

Query: 66  HPLIY----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLM 121
           +  ++     L   L GD   +V    ++   L   +GEY  +  I    +       ++
Sbjct: 111 YIYLHYIPASLFANLFGDTKIVVFTLIRLTIGLFCLLGEYYAFDAICKKINIATGRFFIL 170

Query: 122 LSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPTNI 181
            S+F+   +   T    ++  M  T   L  +       G + +     F + +  P + 
Sbjct: 171 FSIFSSGMFLASTAFVPSSFCMAITFYILGAYLNENWTAGIFCV----AFSTMVGWPFSA 226

Query: 182 LIWIPLGIWLLISIRITLKWVALSFLEVVLILLINTA-LDYFYQKLTFPLYNFLEFNVFY 240
           ++ +P+   +L+   + ++++  S +  + I  +      +++ K      N   +NV  
Sbjct: 227 VLGLPIVADMLLLKGLRIRFILTSLVIGLCIGGVQVITDSHYFGKTVLAPLNIFLYNVVS 286

Query: 241 KNLSIFYGTAPWYFYIFQ--------------AIPLMLMLYLPLM------IYGLKKN-- 278
                 YG  P  FYI                  PL L  +  +       +   ++   
Sbjct: 287 GPGPSLYGEEPLSFYIKNLFNNWNIVIFAAPFGFPLSLAYFTKVWMSQDRNVALYQRFAP 346

Query: 279 --ILLLTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLGILLNICIG 336
             +L +T   +++ F    HKE RF++PI+P + +F A          +    + NI   
Sbjct: 347 IILLAVTTAAWLLIFGSQAHKEERFLFPIYPFIAFFAALALDATNRLCLKKLGMDNILSI 406

Query: 337 LFFTNV 342
           LF    
Sbjct: 407 LFILCF 412
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
 gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
 emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
 gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
          Length = 488

 Score =  254 bits (645), Expect = 2e-66
 Identities = 73/394 (18%), Positives = 150/394 (37%), Gaps = 44/394 (11%)

Query: 1   MTKSTVLSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVY------GYGYLT 54
           M          L   + +        I  + + +E F  L+  H  +Y       Y +L 
Sbjct: 1   MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFN-LQATHDLLYHWQDLEQYDHLE 59

Query: 55  WEWKQQL--RSAIHPLIYVLG-------YKLVGDNTTLVCISPKVINALIAAIGEYNLYK 105
           +     +  R+ + P++  +          L+  +     +  + +  L    G + L K
Sbjct: 60  F---PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQK 116

Query: 106 FIIVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYI 165
            +  +    +A +   ++       +  TR+  N L +   +LAL  W  ++     W  
Sbjct: 117 EVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLS 176

Query: 166 SLGFGFVSCIIRPTNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINT--ALDYFY 223
                F   + R    L    L +  L + ++++       +   ++ L  T     YF+
Sbjct: 177 ----AFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFW 232

Query: 224 QKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLM---LYLPLMIYGLKKNIL 280
           ++LT+P    L +N    N S  +GT+P  +Y + A+P  L    L++PL +   + +  
Sbjct: 233 RQLTWPEGKVLWYNTVL-NKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAP 291

Query: 281 LLTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYV--------KFKPKFVLLGILLN 332
            +  L ++  +SL+ HKE RFI    P+L    ARG           +  K   L ++ +
Sbjct: 292 TVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGH 351

Query: 333 ICI-------GLFFTNVHERGVIDLKYLATQQTP 359
           + +        L+ ++ +  G + ++ L     P
Sbjct: 352 LVVNAAYSATALYVSHFNYPGGVAMQRLHQLVPP 385
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
           mannosyltransferase [Homo sapiens]
          Length = 488

 Score =  253 bits (642), Expect = 4e-66
 Identities = 73/394 (18%), Positives = 149/394 (37%), Gaps = 44/394 (11%)

Query: 1   MTKSTVLSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVY------GYGYLT 54
           M          L   + +        I  + + +E F  L+  H  +Y       Y +L 
Sbjct: 1   MAGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFN-LQATHDLLYHWQDLEQYDHLE 59

Query: 55  WEWKQQL--RSAIHPLIYVLG-------YKLVGDNTTLVCISPKVINALIAAIGEYNLYK 105
           +     +  R+ + P++  +          L+  +     +  + +  L    G + L K
Sbjct: 60  F---PGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQK 116

Query: 106 FIIVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYI 165
            +  +    +A +   ++          TR+  N L +   +LAL  W  ++     W  
Sbjct: 117 EVRRHFGAMVATMFCWVTAMQFHLMVYCTRTLPNVLALPVVLLALAAWLRHEWARFIWLS 176

Query: 166 SLGFGFVSCIIRPTNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINT--ALDYFY 223
                F   + R    L    L +  L + ++++       +   ++ L  T     YF+
Sbjct: 177 ----AFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFW 232

Query: 224 QKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLM---LYLPLMIYGLKKNIL 280
           ++LT+P    L +N    N S  +GT+P  +Y + A+P  L    L++PL +   + +  
Sbjct: 233 RQLTWPEGKVLWYNTVL-NKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAP 291

Query: 281 LLTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYV--------KFKPKFVLLGILLN 332
            +  L ++  +SL+ HKE RFI    P+L    ARG           +  K   L ++ +
Sbjct: 292 TVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGH 351

Query: 333 ICI-------GLFFTNVHERGVIDLKYLATQQTP 359
           + +        L+ ++ +  G + ++ L     P
Sbjct: 352 LVVNAAYSATALYVSHFNYPGGVAMQRLHQLVPP 385
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
          Length = 570

 Score =  243 bits (616), Expect = 5e-63
 Identities = 68/337 (20%), Positives = 136/337 (40%), Gaps = 25/337 (7%)

Query: 7   LSSYKLFAFIFI--FRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLR 62
                   FI +   R  ++ +       DE F   EP H+ +Y  G+ TWE+     LR
Sbjct: 42  GGLRWFLPFIALCYLRYMSATS-NIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALR 100

Query: 63  SAIHPLIYVLGYK----LVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWI 118
           S ++ L + L  +      GD+   V  + ++   L++A+ +  L   +     +++A  
Sbjct: 101 SYLYILFHELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATY 160

Query: 119 TLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRP 178
            + +       ++  T    ++  M    L+     + K         +G      +  P
Sbjct: 161 AVAMLCLTSGCFFASTSFLPSSFSMYAISLSSGLLLFEKYAMAVAVSVVGV----ILGWP 216

Query: 179 TNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINTALDYFYQKLTFPLYNFLEFNV 238
            +IL ++P+ I+ L+  R    ++A +   + L+ +      Y+Y++ T  + N L +NV
Sbjct: 217 FSILAFLPVVIYSLV-KRFKQAFIAGAVTTIFLLGVSLLVDYYYYKRWTSSVLNLLIYNV 275

Query: 239 FYKNLSIFYGTAPWYFYI---------FQAIPLMLMLYLPLMIYGLKKNILLL--TGLFY 287
                S  YGT    FYI            + ++ +   P++     + +L++      +
Sbjct: 276 LGGGESHLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW 335

Query: 288 IIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKF 324
           +   SL  HKE RF+YPI+P++    +         F
Sbjct: 336 LAFMSLQPHKEERFLYPIYPLICVSASAVIENIPELF 372
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
           lipid-linked oligosaccharides; Alg9p [Saccharomyces
           cerevisiae]
 sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
 pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
 emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
          Length = 555

 Score =  238 bits (603), Expect = 2e-61
 Identities = 74/340 (21%), Positives = 132/340 (38%), Gaps = 18/340 (5%)

Query: 9   SYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIH 66
           +  L   +F+ R+            DE F   EP +  V G+G  TWE+     +RS   
Sbjct: 7   TISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYSIRSWAF 66

Query: 67  PLIYVLGY----KLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLML 122
            L +        K     +       +      + I E+ L++ I    + ++A I ++ 
Sbjct: 67  LLPFYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQIANIWIIF 126

Query: 123 SLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKK--INGSWYISLGFGFVS-CIIRPT 179
            LFNP  ++       + + M+  V A R            ++  SL + F++  +  P 
Sbjct: 127 QLFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGSTSNFTKSLAYNFLASILGWPF 186

Query: 180 NILIWIPLGIWLLISIRITLKWVA---LSFLEVVLILLINTALDYFYQKLTFPLYNFLEF 236
            +++ +PL +  L + RI            +  +    +      FY KL    +N L +
Sbjct: 187 VLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAPVSWNILFY 246

Query: 237 NVFY---KNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYG---LKKNILLLTGLFYIIG 290
           NV     ++    +G  PWY+Y    +    +  L L I G   L+   L  +   +I  
Sbjct: 247 NVINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHLRLWPLWASLFTWIAV 306

Query: 291 FSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLGIL 330
           F+   HKE RF+YPI+ ++    +  + K    F    IL
Sbjct: 307 FTQQPHKEERFLYPIYGLITLSASIAFYKVLNLFNRKPIL 346
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
 gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
          Length = 492

 Score =  230 bits (582), Expect = 4e-59
 Identities = 49/353 (13%), Positives = 121/353 (33%), Gaps = 40/353 (11%)

Query: 16  IFIFRLANSFAIETFFQADEFFQALEPAHHFVY-------GYGYLTWEWKQQL--RSAIH 66
           I I        +    + +E F  ++  H  ++        Y +  +     +  R+ I 
Sbjct: 7   IVIIVTIIHIILAPGTKVEESFN-VQATHDLMFHLPTNLSNYDHSQF---PGVVPRTFIG 62

Query: 67  PL-------IYVLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWIT 119
           P+            ++          +  +    L+ A+      + +      + A   
Sbjct: 63  PISLAILSSPMSFIFRFWAIPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFGRETAMYL 122

Query: 120 LMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPT 179
            ++        + ++R   N   ++  ++      + + + G +  ++ +   S I+   
Sbjct: 123 RLIMCTQFHYIFYMSRPLPNTFALILVMI-----VFERLLEGRYESAVRYATASVILFRC 177

Query: 180 NILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINT------ALDYFYQKLTFPLYNF 233
            +++         +       +     + + + +             YF+ +  +P    
Sbjct: 178 ELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFWGRPLWPEGEV 237

Query: 234 LEFNVFYKNLSIFYGTAPWYFYIFQAIPL----MLMLYLPLMIYGLKKNILLLTGLFYII 289
           + FNV  +N S  YGT P+ +Y + A+P       +L    ++   +   ++L  + +I 
Sbjct: 238 MFFNVV-ENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQIVLPSVIFIF 296

Query: 290 GFSLIQHKEFRFIYPIHPILLY----FTARGYVKFKPKFVLLGILLNICIGLF 338
            +S + HKE RFI  + PI       F AR  +     F  + +   + + L 
Sbjct: 297 LYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFFRMILFFGVILHLL 349
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
 dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
          Length = 579

 Score =  228 bits (576), Expect = 2e-58
 Identities = 74/441 (16%), Positives = 142/441 (31%), Gaps = 73/441 (16%)

Query: 12  LFAFIFIFRLANSFAIET-FFQADEFFQALEPAHHFVYG-YGYLTWEW--KQQLRSAIHP 67
           L+  + + R+      +T +   DEFFQ+ E     + G      WE+      RS + P
Sbjct: 37  LWGGLSLLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFP 96

Query: 68  LIYVL-------GYKLVGD-----NTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKL 115
           L+           ++ +G      +   + + P+++   ++   +  +Y       +++ 
Sbjct: 97  LLISGSTFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGADR- 155

Query: 116 AWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRF------WPWNKKINGS-----WY 164
            W  L L   +       TR+FSN +E +     L        W   +K          +
Sbjct: 156 -WNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSW 214

Query: 165 ISLGFGFVSCIIRP-TNILIWIPLGIWLL--ISIRITLKWV--ALSFLEVVLILLINTA- 218
           +  G        RP       +PL +W     +          AL  L    +       
Sbjct: 215 LLGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVLLPGATLTAAVFVA 274

Query: 219 -LDYFY------QKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPL- 270
              +++      + L     NFL +N+  +NL+  +GT     ++     L+  +     
Sbjct: 275 TDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLAR-HGTHARLTHLAVNGFLLFGVLHAQA 333

Query: 271 ---------------------------MIYGLKKNILLLTGLFYIIGFSLIQHKEFRFIY 303
                                       +    ++ LLL     +   S   H+E RF+ 
Sbjct: 334 LQAAWQQLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLI 393

Query: 304 PIHPILLYFTARGYVKFKPKFVLLGILLNICIGLFFTNVHERGVIDLKYLATQQTPTSVG 363
           P+   L+   +        K     +L N    L F  +H+ G++       Q     V 
Sbjct: 394 PLLVPLVLLCSPQTQPVPWKG--TVVLFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVL 451

Query: 364 FITPCHSTPWQSYFHNPNLDT 384
             TP H T   ++ + P    
Sbjct: 452 PSTPTHYTLLFTHTYMPPRHL 472
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
           architecture [Schizosaccharomyces pombe]
          Length = 547

 Score =  226 bits (571), Expect = 9e-58
 Identities = 75/398 (18%), Positives = 141/398 (34%), Gaps = 50/398 (12%)

Query: 11  KLFAFIFIFRLANSFAIETFF-QADEFFQALEPAH-------HFVYGYGYLTWEWKQQL- 61
              A I +      ++ +T F + +E F A++  H            Y +L  E+   + 
Sbjct: 9   WYLANILLVTCIGYYSYKTPFTKVEESF-AMQAIHDIQTYRWDLSKVYDHL--EFPGAVK 65

Query: 62  RSAIHPLIYVLGYKLVGDNTTLV--CISPKVINALIAAIGEYNLYKFIIVYDSEKLAWIT 119
           RS I  L   +   +    +  V   ++ +     ++     ++   I          + 
Sbjct: 66  RSFIPSLFIAVLSYI---PSWFVNPLLAARWTIGYLSWESMNSVSCSISKRFGTLSGALF 122

Query: 120 LMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCIIRPT 179
           ++ S       Y ++R  SN   ++ T  +L         N  +       F + I+R  
Sbjct: 123 ILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLL----KNNYYGSISILVFAAAIVRSE 178

Query: 180 NILIWIPLGIWLLISIRITLKWVALSFL--EVVLILLINTALDYFYQKLTFPLYNFLEFN 237
             L+ + L + LL+  RITL  + L  +   +  +        YF+    +P      FN
Sbjct: 179 IALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWPELEAFLFN 238

Query: 238 VFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKK------NILLLTGLFYIIGF 291
           V  +  S  +GT+P+Y+Y  + +P + +    L+   +         +L+   LF+I  +
Sbjct: 239 VV-EGKSSDWGTSPFYYYFVR-LPWLFLNPTTLLFLLISFVYIKPARLLIYVPLFFIFVY 296

Query: 292 SLIQHKEFRFIYPIHPILLYFTARGYV-------------KFKPKFVLLGILLNICIGLF 338
           S + HKE+RFI    P     +A G               +        GI+       F
Sbjct: 297 SFLGHKEWRFIIYSIPWFNAASAIGASLCFNASKFGKKIFEILRLMFFSGIIFGFIGSSF 356

Query: 339 FTNVHE---RGVIDLKYLATQQTPTSVGFIT---PCHS 370
              V +    G + L  L   +    V       PC +
Sbjct: 357 LLYVFQYAYPGGLALTRLYEIENHPQVSVHMDVYPCMT 394
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
          Length = 516

 Score =  224 bits (568), Expect = 2e-57
 Identities = 80/402 (19%), Positives = 148/402 (35%), Gaps = 42/402 (10%)

Query: 11  KLFAFIFIFRLANSFAIETFFQADEFFQALEP-AHHFVYGYGYLTWEWKQQL--RSAIHP 67
                ++   L       ++   DE FQ +E  A  F+   G + WE+K +   RS    
Sbjct: 6   WWLYLVYAIGLMLC-LGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPL 64

Query: 68  LI-YVLGYKLV------GDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITL 120
           L+ Y   + ++       DN  L+  S ++ N ++  +  + L   +I  + + + +I  
Sbjct: 65  LLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFIKK 124

Query: 121 MLSLFNPFNWYVITRSFSNNLEMVFTVLALRFW--------PWNKKINGSWYISLGFGFV 172
            L L +   W   T +FSN++E +  +  L              +    S  + L F F 
Sbjct: 125 SLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNGKNIQRRNFKNSVILGLIFSFG 184

Query: 173 SCIIRPTNILIWIP--LGIWLLISIRITLKWVALSFLEVVLILLINTALDYF--YQKLTF 228
                     I++P  +  W    +      + L        L +    + +   +    
Sbjct: 185 VFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVI 244

Query: 229 PLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKNILLLT--GLF 286
              N L++N+  +NL   +G  P Y ++   +P +L   L L I+   K   L T   + 
Sbjct: 245 TPLNNLKYNLNVQNL-QVHGLHPRYTHLLVNLPQILGPVLLLAIFSGYKLDKLSTYAIIS 303

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLL---------GILLNICIGL 337
            ++  S  QH+E RF+ P+ P+L+       + + P    L          +L NI +  
Sbjct: 304 GLLFLSFFQHQELRFLVPLVPLLV-----TNLNWTPLSSTLVNKKIFKGTWLLFNIIMAF 358

Query: 338 FFTNVHERGVIDLK--YLATQQTPTSVGFITPCHSTPWQSYF 377
                H+ G+I     Y   +     V      +S P   Y 
Sbjct: 359 IMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYM 400
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
           most likely an alpha 1,2 mannosyltransferase utilized
           for addition of the fourth, side-branching mannose onto
           the GPI core structure.; Smp3p [Saccharomyces
           cerevisiae]
 sp|Q04174|SMP3_YEAST SMP3 PROTEIN
 pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
 gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
 emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
          Length = 516

 Score =  222 bits (562), Expect = 1e-56
 Identities = 78/402 (19%), Positives = 147/402 (36%), Gaps = 42/402 (10%)

Query: 11  KLFAFIFIFRLANSFAIETFFQADEFFQALEP-AHHFVYGYGYLTWEWKQQL--RSAIHP 67
                ++   L       ++   DE FQ +E  A  F+   G + WE+K +   RS    
Sbjct: 6   WWLYLVYAIGLMLC-LGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGPL 64

Query: 68  LI-YVLGYKLV------GDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITL 120
           L+ Y   + ++       DN  L+  S ++ N ++  +  + L   +I  + + + ++  
Sbjct: 65  LLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQK 124

Query: 121 MLSLFNPFNWYVITRSFSNNLEMVFTVLALRFW--------PWNKKINGSWYISLGFGFV 172
            L L +   W   T +FSN++E +  +  L                   S  + L F F 
Sbjct: 125 SLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFG 184

Query: 173 SCIIRPTNILIWIP--LGIWLLISIRITLKWVALSFLEVVLILLINTALDYF--YQKLTF 228
                     I++P  +  W    +      + L        L +    + +   +    
Sbjct: 185 VFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVI 244

Query: 229 PLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKNILLLT--GLF 286
              N L++N+  +NL   +G  P Y ++   +P ++   L L I+   K   L T   + 
Sbjct: 245 TPLNNLKYNLNVQNL-QVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYAIIS 303

Query: 287 YIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLL---------GILLNICIGL 337
            ++  S  QH+E RF+ P+ P+L+       + + P    L          +L NI +  
Sbjct: 304 GLLFLSFFQHQELRFLVPLVPLLV-----TNLNWTPLSSTLVNKKIFKGTWLLFNIIMAF 358

Query: 338 FFTNVHERGVIDLK--YLATQQTPTSVGFITPCHSTPWQSYF 377
                H+ G+I     Y   +     V      +S P   Y 
Sbjct: 359 IMGISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYM 400
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
 pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
          Length = 533

 Score =  221 bits (560), Expect = 2e-56
 Identities = 69/390 (17%), Positives = 148/390 (37%), Gaps = 41/390 (10%)

Query: 11  KLFAFIFIFRLANSFAI---ETFFQADEFFQALEPAHHFVYGYGY-LTWEWK--QQLRSA 64
           + +A I+ F L   F      ++   DE  Q+ +   + ++G+   L WE+   + +RS 
Sbjct: 5   RKYAIIYTFLLILRFWFSQGSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSV 64

Query: 65  IHPLIYVLGYKLV-------GDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAW 117
           +   + +L   L+         +   + +  ++   LI+ + + +++  + +      A 
Sbjct: 65  VPLNVMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLIDLSIWNIVPLN-----AR 119

Query: 118 ITLMLSLFNPFNW-YVITRSFSNNLEMVFTVLALRFW----PWNKKINGSWYISLGFGFV 172
            + +L   + F      T +F+N++E +F  L + F             S+  +     V
Sbjct: 120 WSALLLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIV 179

Query: 173 SCIIR-------PTNILIWIPLGIWLLISIRITLKWVALSF-----LEVVLILLINTALD 220
           S +            I  +I   +          K + L       +    +L       
Sbjct: 180 SVLGFFTRITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDY 239

Query: 221 YFYQKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPL-MIYGLKKNI 279
            FY       +N L++N   +NLS  +G      + F  +PL+    + +  ++ ++K  
Sbjct: 240 KFYGVFVITFWNNLKYNSQIENLSQ-HGLHSRLTHFFTNMPLLCGPLIFVPKLWDVRKPA 298

Query: 280 LLLTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLGILLNICIGLFF 339
             L  L  +   SL  H+E RF+ P   I +  +      +  KF+ +     + + +FF
Sbjct: 299 TWLW-LLPVFILSLFPHQEPRFLLPAASIFIVNSGCLVRSYWIKFLFVMYA--VVLAVFF 355

Query: 340 TNVHERGVID-LKYLATQQTPTSVGFITPC 368
             +H+ GVI  +  +       +V  +  C
Sbjct: 356 GIMHQNGVIPAVLEVKNIIEQRNVTTMENC 385
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
          Length = 278

 Score =  217 bits (548), Expect = 5e-55
 Identities = 85/264 (32%), Positives = 130/264 (49%), Gaps = 44/264 (16%)

Query: 259 AIPLMLMLYLPLMIYGLKKN---------------ILLLTGLFYIIGFSLIQHKEFRFIY 303
           A+P++L   +P   +GL                   + LT L  ++ +S + HKEFRFI+
Sbjct: 1   ALPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIF 60

Query: 304 PIHPILLYFTARGYVKFKPKF----------VLLGILLNICIGLFFTNVHERGVID-LKY 352
           P+ P+ +  ++ G ++    +          + L   +++ I L     HE G I+ +K+
Sbjct: 61  PLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVMKF 120

Query: 353 LATQQTPTSVGFITPCHSTPWQSYFHNPNLDTNSWFLACEPPLHL--NKPSMEEIRHYRD 410
           L  +    S+GFI PCHSTP QSY H  ++  + W + C PPLHL  +  +  ++  Y D
Sbjct: 121 LHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQ-DLWSITCNPPLHLLGDPEAYSKLETYMD 179

Query: 411 QSDQFYDAPESFLQTHLG----KDLPK---------TEQLVVFEPLE-PLMNDYL-GREY 455
           +SD  YD   +F+  +      KDL              LVVFE +E   + D+L    Y
Sbjct: 180 ESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENAFLKDFLKDSSY 239

Query: 456 YECQRFYNSFFHWDSRRDGDIIVY 479
            E  RF+NS  HWDSRR GDII+Y
Sbjct: 240 IEYNRFFNSLAHWDSRRSGDIIIY 263
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
          Length = 369

 Score =  212 bits (537), Expect = 7e-54
 Identities = 44/313 (14%), Positives = 109/313 (34%), Gaps = 32/313 (10%)

Query: 49  GYGYLTWEWKQQL--RSAIHPL-------IYVLGYKLVGDNTTLVCISPKVINALIAAIG 99
            Y +  +     +  R+ I P+            ++          +  +    L+ A+ 
Sbjct: 4   KYDHSQF---PGVVPRTFIGPISLAILSSPMSFIFRFWAIPKMWQLLLIRATLGLMNAMA 60

Query: 100 EYNLYKFIIVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKI 159
                + +      + A    ++        + ++R   N   ++  ++      + + +
Sbjct: 61  FLYFARSVNRKFGRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMI-----VFERLL 115

Query: 160 NGSWYISLGFGFVSCIIRPTNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINT-- 217
            G +  ++ +   S I+    +++         +       +     + + + +      
Sbjct: 116 EGRYESAVRYATASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLA 175

Query: 218 ----ALDYFYQKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPL----MLMLYLP 269
                  YF+ +  +P    + FNV  +N S  YGT P+ +Y + A+P       +L   
Sbjct: 176 VSIPIDSYFWGRPLWPEGEVMFFNVV-ENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPL 234

Query: 270 LMIYGLKKNILLLTGLFYIIGFSLIQHKEFRFIYPIHPILLY----FTARGYVKFKPKFV 325
            ++   +   ++L  + +I  +S + HKE RFI  + PI       F AR  +     F 
Sbjct: 235 GLLVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFF 294

Query: 326 LLGILLNICIGLF 338
            + +   + + L 
Sbjct: 295 RMILFFGVILHLL 307
>ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
 pir||S75173 hypothetical protein sll1946 - Synechocystis sp. (strain PCC 6803)
 dbj|BAA17087.1| (D90903) ORF_ID:sll1946~unknown protein [Synechocystis sp. PCC
           6803]
          Length = 825

 Score =  200 bits (504), Expect = 7e-50
 Identities = 62/392 (15%), Positives = 127/392 (31%), Gaps = 65/392 (16%)

Query: 1   MTKSTVLSSYKLFAFIFIFRLA-NSFAIETFFQADEFFQALEPAHHFVYGYGYLT----- 54
           M K   LS       +       ++     +   D+   A + ++H  YG  YL      
Sbjct: 1   MVKQI-LSKSWGVPLLLAMVWLGSNGLDRLWLGMDQTVPAWDQSNHLSYGLEYLQALRSP 59

Query: 55  -----------WEWKQQLRSAIHPLIYVLGYKLVGDNTTLVCISPKVINALIAAIGEYNL 103
                      W    +     +  +      L G  + L  +S    N L + I   ++
Sbjct: 60  EFLSGEWWRSFWMLSPKYPPLTYI-VNAPFQGLGGPGSDLALLS----NWLWSGILILSV 114

Query: 104 YKFIIVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLA---LRFWPWNKKIN 160
           Y       S ++    + + +  P   +       ++  + FT+L+   L +W   +   
Sbjct: 115 YGLGKKLFSREIGLWAVAIMVLIPRLIHSRLIVLLDSPLLAFTLLSFTCLTYWKEAEGRR 174

Query: 161 GSWYISLGFGFVSCIIRPT------NILIWIPLGIWLLISIRITLKWVALSFLEVVLILL 214
             W     +   + +          +I+ ++   +  L    I  K        +V +L 
Sbjct: 175 SQW----LWAIAAGVGLGLGLLSKQSIIFYLFFPLVGLGLWSIWTKQWQRLAQLLVGLLA 230

Query: 215 INTALDYFYQ-KLTFPLYNFLEFNVFY---KNLSIFYGTAPWYFY---IFQAIPLM-LML 266
                  +Y+    +        N      +        A W +Y   +  A+  + L+ 
Sbjct: 231 SIPLWYPWYRTNWIYLFSTAQNSNAIPATLEGDPPVNTLAAWTYYWQDLPNALSWVWLIP 290

Query: 267 YLPLMIYGL--KKNILLL--------TGLFYIIGF--------SLIQHKEFRFIYPIHPI 308
            L  +I  L  +    L          GL ++  +        S IQ+K+ R+I P  PI
Sbjct: 291 PLVGVILSLLNRFPASLQIPSWREAKPGLLWLGYYYGGTYLICSAIQNKDDRYILPYLPI 350

Query: 309 LLYFTARGYVKFKPKFVLL---GILLNICIGL 337
           +  F A G  ++  +++ +    + + I I L
Sbjct: 351 VAIFLAFGLTRWCGRWLWVRWGTLAITILITL 382
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
          Length = 509

 Score =  195 bits (493), Expect = 1e-48
 Identities = 79/331 (23%), Positives = 141/331 (41%), Gaps = 29/331 (8%)

Query: 3   KSTVLSSYKL---FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ 59
           KS   S   +          R+   F I  ++  DE FQ LE AH   +GY  + WE++ 
Sbjct: 14  KSIQASHLTVLLITLLALCLRMTAIFPI-GYYHPDEIFQYLEQAHRLAFGYSVIPWEYRY 72

Query: 60  QLRSAIHPLIYVLGYK---LVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLA 116
            +R  + P++     K   ++   + L  + P  I AL++    ++ YK   ++     +
Sbjct: 73  GMRGGLVPVLLAAAMKMGDIMNTQSFLYWVLPHAITALLSLGVIWSAYKLGRLH-----S 127

Query: 117 WITLMLSLFNPFNWYVIT----RSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFV 172
           + T  L++F    WY I        S +L     + A  +    +K   S  +S     +
Sbjct: 128 FFTGCLAMFVAATWYEIVLFAAHPLSESLSFAAFMPAAYYLIAEEKKKSSLILSGFLMGL 187

Query: 173 SCIIRPTNILIWIPLGIW-LLISIRITLKWVALSFLEVVLILLINTALDYFYQK--LTFP 229
           S ++R      +IP  ++  L ++RI ++      L  +  + I++  D F  +  L + 
Sbjct: 188 SALLR----FQYIPSILFITLFTLRINVRQWGYFILGGLGAVFISSLSDIFIGEYPLLWL 243

Query: 230 LYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIP----LMLMLYLPLMIYGLKKNILLLTGL 285
             N  +  +F++     YGTAP Y Y F          L+L +P+++   +   L  T L
Sbjct: 244 FKNIQQNLIFHRAED--YGTAPIYSYFFDIWTNWKWFSLILPIPILVAAYRYPALFGTAL 301

Query: 286 FYIIGFSLIQHKEFRFIYPIHPILLYFTARG 316
             +I   L+ HKE+RFI+    I +   A G
Sbjct: 302 VNLIFHMLVSHKEYRFIFLSSGIFIILAAIG 332
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
 sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
 pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
          Length = 551

 Score =  195 bits (493), Expect = 1e-48
 Identities = 67/431 (15%), Positives = 133/431 (30%), Gaps = 78/431 (18%)

Query: 9   SYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVY-------GYGYLTWEWKQQL 61
            + +   + +  ++       F + +E F  ++  H  +         Y +L +     +
Sbjct: 2   RWSVLDTVLLTVISFHLIQAPFTKVEESFN-IQAIHDILTYSVFDISQYDHLKF---PGV 57

Query: 62  --RSAIHPLIYV----------LGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIV 109
             R+ +  +I               +     +  V +  + I  L   +    L   +  
Sbjct: 58  VPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQD 117

Query: 110 YDSEKL------------------AWITLMLSLFNPFNWYVITRSFSN-NLEMVFTVLAL 150
              E                        L+  + +    +  TR+  N  + +  T +AL
Sbjct: 118 MFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVAL 177

Query: 151 RFWPWNKKINGSWYISLGFGFVSCIIRPT-NILIWIPLGIWLLISIRITLKWVALSFLEV 209
             W    + N + ++S     V+ + R   + L        ++         +      +
Sbjct: 178 G-WVLLGRYNAAIFLS---ALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGL 233

Query: 210 VLILL-INTALDYFYQKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYL 268
            L      T   YF+Q+   P  +   FNV     S  +G  P   Y    + +M M   
Sbjct: 234 GLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASK-WGVEPVTAYFTHYLRMMFMPPT 292

Query: 269 PLMI--YGLKKN-----ILLLTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFK 321
            L++  +G K       I+ L  LF+II  S   HKE+RFI    P ++   A G     
Sbjct: 293 VLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLW 352

Query: 322 ---------------PKFVLLGILLNICIG-LFFTNVHERGVIDLKYLATQQTPTSVG-- 363
                             + +     I +  L+ + ++  G   L          ++   
Sbjct: 353 ENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGEALTSFNDMIVEKNITNA 412

Query: 364 ----FITPCHS 370
                I PC +
Sbjct: 413 TVHISIPPCMT 423
>ref|NP_488386.1| (NC_003272) hypothetical protein [Nostoc sp. PCC 7120]
 dbj|BAB76045.1| (AP003596) ORF_ID:alr4346~hypothetical protein [Nostoc sp. PCC
           7120]
          Length = 812

 Score =  192 bits (484), Expect = 1e-47
 Identities = 68/384 (17%), Positives = 116/384 (29%), Gaps = 60/384 (15%)

Query: 8   SSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGY--------------- 52
               +   I  F     F    +F  D+   A + + H      +               
Sbjct: 10  KRDYIILLIIFFVTL--FIDRIWFFIDDSIPAYDQSAHLTTVLHHYRIFQNFNIFSGDWW 67

Query: 53  -LTWEWKQQLR-SAIHP--LIYVLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFII 108
              WE     R   ++   + ++  +    D  +LV       N L  AI   ++Y   I
Sbjct: 68  LSLWEITPSYRAPFVYICTVPFLFLFGRGYDQASLV-------NLLYTAIIIVSVYSLGI 120

Query: 109 VYD-SEKLAWITLMLSLFNPFNWYVITRSFSN---NLEMVFTVLALRFWPWNKKINGSWY 164
               + K A    +  L  P    + T    +      +  T   L  W   K    +W 
Sbjct: 121 YLFKNRKTAITASIFCLLFPVLGIIRTDYLLDYGLTAIIALTFTILTIWKDRKTGFSAWL 180

Query: 165 ISLGFGFVSCII---RPTNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLINTALDY 221
           ++LG G    +I   +PT  +     GI  LIS      ++ L    + LI+       +
Sbjct: 181 LTLGLGISLGLIMLAKPTGFIFIFIPGILTLISFVRKGSYLKLIQSGLSLIVAWLVCGFW 240

Query: 222 FYQKLTFPLYNFLEFNVFYK--NLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKNI 279
           +       + + L  N   +          A W  Y  Q IP  + L +  +  G     
Sbjct: 241 YGLNWLTIITSALNANRVGQREGDPPATTIAGWLVY-PQMIPDTIGLPILFVSIGTLLVY 299

Query: 280 LL--------------LTGLFYIIGF--------SLIQHKEFRFIYPIHPILLYFTARGY 317
           L                + L ++I F        SL  +K+ RFI P  PI+    +   
Sbjct: 300 LWQNKFDFHVIKNKWHQSSLNWLIIFLLSSYVICSLGTNKDIRFILPCFPIISLILSYFC 359

Query: 318 VKFKPKFVLLGILLNICIGLFFTN 341
                K+     +  I +      
Sbjct: 360 NLIDNKWFSRLRITTIGLSFIVLL 383
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
          Length = 830

 Score =  190 bits (479), Expect = 6e-47
 Identities = 81/473 (17%), Positives = 146/473 (30%), Gaps = 134/473 (28%)

Query: 7   LSSYKLFAFIFIFRLANSFAIET-FFQADEFFQALEPAHHFVYGYGY-LTWEWKQQLRSA 64
           LS+Y  FA     RL   F  +  +   DEFFQ++E      +   +  TWE+   L   
Sbjct: 17  LSTYFCFA---AVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVR 73

Query: 65  IHPLIYVLG-----------------YKLVGDNTTLVCISPKVINALIAAIGEYNLYKFI 107
              L + L                  ++L    T    + P++I  LI+   +Y L++ I
Sbjct: 74  SIVLPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-I 132

Query: 108 IVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVF---------------------- 145
                 +     L +   +       TR+FSN+LEM                        
Sbjct: 133 CRLYGLRFEIRLLAMG-SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKK 191

Query: 146 ----------TVLALRFWPWNKKINGSWYISLGFGFVS------CIIRPTNILIWIPLGI 189
                       ++ R   W  K +   +       +S         RPT +L   P+  
Sbjct: 192 EFLEEKYDKAESISERVRIWKLKNSLPAHNLQHLMAMSTICVAGVFNRPTFLLFGAPMVF 251

Query: 190 WLLIS---------IRITLKWVALSFLEVVLILLINTALDYFYQ---------------K 225
           + L+              L+        +  ++L       +YQ                
Sbjct: 252 FWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDN 311

Query: 226 LTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKNILL---- 281
             F  +NF++ N      +  +G  P Y ++   +P++  +     +    + +L     
Sbjct: 312 FVFTPWNFIKAN-LDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRA 370

Query: 282 ----------------LTGLFYIIGFSLIQHKEFRFIYPI-HPILLYFTARGYVKFKPKF 324
                                 +   SLI H+E RF+ P+  P++L    +    F  K+
Sbjct: 371 EYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKY 430

Query: 325 VL--------------------------LGILLNICIGLFFTNVHERGVIDLK 351
                                       +  + N+ + LFF  +H+ GV  L 
Sbjct: 431 PFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAGVYPLA 483
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
          Length = 457

 Score =  172 bits (434), Expect = 1e-41
 Identities = 55/320 (17%), Positives = 95/320 (29%), Gaps = 55/320 (17%)

Query: 117 WITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRF------WPWNKKINGS-----WYI 165
           W  L L   +       TR+FSN +E +     L        W   +K          ++
Sbjct: 34  WNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWL 93

Query: 166 SLGFGFVSCIIRP-TNILIWIPLGIWLL--ISIRITLKWV--ALSFLEVVLILLINTA-- 218
             G        RP       +PL +W     +          AL  L    +        
Sbjct: 94  LGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVLLPGATLTAAVFVAT 153

Query: 219 LDYFY------QKLTFPLYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPL-- 270
             +++      + L     NFL +N+  +NL+  +GT     ++     L+  +      
Sbjct: 154 DSWYFSSPATSRNLVLTPVNFLHYNLNPQNLAR-HGTHARLTHLAVNGFLLFGVLHAQAL 212

Query: 271 --------------------------MIYGLKKNILLLTGLFYIIGFSLIQHKEFRFIYP 304
                                      +    ++ LLL     +   S   H+E RF+ P
Sbjct: 213 QAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIP 272

Query: 305 IHPILLYFTARGYVKFKPKFVLLGILLNICIGLFFTNVHERGVIDLKYLATQQTPTSVGF 364
           +   L+   +        K      L N    L F  +H+ G++       Q     V  
Sbjct: 273 LLVPLVLLCSPQTQPVPWKG--TVALFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVLP 330

Query: 365 ITPCHSTPWQSYFHNPNLDT 384
            TP H T   ++ + P    
Sbjct: 331 STPTHYTLLFTHTYMPPRHL 350
>gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protein MGC3136 [Mus musculus]
          Length = 385

 Score =  156 bits (393), Expect = 7e-37
 Identities = 34/229 (14%), Positives = 72/229 (30%), Gaps = 25/229 (10%)

Query: 3   KSTVLSSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVY------GYGYLTWE 56
           K +          + +        I  + + +E F  L+  H  +Y       Y +  + 
Sbjct: 4   KKSSGKRSWPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHHEF- 61

Query: 57  WKQQL--RSAIHPLIYVLG-------YKLVGDNTTLVCISPKVINALIAAIGEYNLYKFI 107
               +  R+ + PL+             L+  +     +  + +  L    G + L K +
Sbjct: 62  --PGVVPRTFLGPLVIAAFSSPVVYVLSLLEVSKFYSQLIVRGVLGLGVISGLWTLQKEV 119

Query: 108 IVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISL 167
                  +A +   +S       +  TR+  N L +   + AL  W   +     W + +
Sbjct: 120 RQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRR-----WALFV 174

Query: 168 GFGFVSCII-RPTNILIWIPLGIWLLISIRITLKWVALSFLEVVLILLI 215
                  I  R    ++     +  L   R+T+  V    +   L+ L 
Sbjct: 175 WLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLG 223
 Score = 35.3 bits (81), Expect = 2.5
 Identities = 17/141 (12%), Positives = 43/141 (30%), Gaps = 35/141 (24%)

Query: 254 FYIFQAIPLMLML---YLPLMIYGLKKNILLLTGLFYIIG-----FSLIQHKE------- 298
           FY  + +P +L L      L  +  ++  L +    ++I       +++           
Sbjct: 143 FYCTRTLPNVLALAVVLPALTAWLQRRWALFVWLSAFVIIGFRAELAMLLGIALLLTLYQ 202

Query: 299 -----FRFIYPIHPILLYFTARGYV--------KFKPKFVLLGILLNICI-------GLF 338
                 R +    P  L    +            +  K   + +  +I +        L+
Sbjct: 203 RRLTVARVLRHAIPAGLLCLGKLASLVCLLNKKSWPYKVRAMLVTGHILVNVAYTATSLY 262

Query: 339 FTNVHERGVIDLKYLATQQTP 359
            ++ +  G + ++ L     P
Sbjct: 263 VSHFNYPGGVAMQQLHELVPP 283
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
          Length = 198

 Score =  143 bits (360), Expect = 5e-33
 Identities = 27/133 (20%), Positives = 54/133 (40%), Gaps = 8/133 (6%)

Query: 13  FAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQ--QLRSAIHPLIY 70
           F  +   RL  +         DE F   EP H+ +YG G+ TWE+     +RS  + L++
Sbjct: 62  FKCLLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120

Query: 71  ----VLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
                   +++  N  LV    + + A ++ I E   YK +       ++ + L   + +
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180

Query: 127 PFNWYVITRSFSN 139
               +  +  + +
Sbjct: 181 TGM-FCSSSVYPS 192
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 197

 Score =  122 bits (304), Expect = 2e-26
 Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 14/203 (6%)

Query: 112 SEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGF 171
                 + ++ S       Y ++R  SN   ++ T  +L         N  +       F
Sbjct: 1   GTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLL----KNNYYGSISILVF 56

Query: 172 VSCIIRPTNILIWIPLGIWLLISIRITLKWVALSFL--EVVLILLINTALDYFYQKLTFP 229
            + I+R    L+ + L + LL+  RITL  + L  +   +  +        YF+    +P
Sbjct: 57  AAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWP 116

Query: 230 LYNFLEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKK------NILLLT 283
                 FNV  +  S  +GT+P+Y+Y  + +P + +    L+   +         +L+  
Sbjct: 117 ELEAFLFNVV-EGKSSDWGTSPFYYYFVR-LPWLFLNPTTLLFLLISFVYIKPARLLIYV 174

Query: 284 GLFYIIGFSLIQHKEFRFIYPIH 306
            LF+I  +S + HKE+RFI    
Sbjct: 175 PLFFIFVYSFLGHKEWRFIIYSI 197
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
           chromosome I precursor [Leishmania major]
          Length = 822

 Score =  116 bits (289), Expect = 1e-24
 Identities = 35/169 (20%), Positives = 59/169 (34%), Gaps = 11/169 (6%)

Query: 12  LFAFIFIFRLAN-----SFAIETFFQADEFFQALEPAHHFVYGYGYLTWEW--KQQLRSA 64
                  F L +     + +       DE F  +EP H+ +YG G  TWE   +  LRS 
Sbjct: 8   YLKMAAAFLLLSLTHYFASSFLPISDCDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSW 67

Query: 65  IHPLIYV----LGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITL 120
           +   I+     L       ++  V    +++N   AA+ E      +    S K A + L
Sbjct: 68  LFLWIHAWPVVLIRGAASLSSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVAL 127

Query: 121 MLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISLGF 169
           +L L N    +        +  M+   + L  W   +    S  +    
Sbjct: 128 LLLLANYPIQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLSRV 176
 Score = 46.2 bits (109), Expect = 0.001
 Identities = 19/141 (13%), Positives = 48/141 (33%), Gaps = 15/141 (10%)

Query: 137 FSNNLEMVFTVLALRFWPWNKKINGSWYISLGFGFVSCI-------IRPTNILIWIPLGI 189
              +     T+ +    P +       ++    G   C          P   LI   +G+
Sbjct: 199 VPPSPSSAPTLHSSSASPPSAPPR---HLCWFIGAALCFSVLAVVTGWPFAALISALVGL 255

Query: 190 WLLISIRITLKWVALSFLEVVLILLINTA-LDYFYQKLTFPLYNFLEFNVFYKN--LSIF 246
            LL+     ++ +A +   +++           +Y + T   +N + +N F  +      
Sbjct: 256 DLLLRFP--VRTLACTLGSLLVACAAVFVADVRYYCRWTLSSWNVVMYNGFGGSGRGPEL 313

Query: 247 YGTAPWYFYIFQAIPLMLMLY 267
           +G  P +F+    +    +++
Sbjct: 314 FGVEPIFFFWKNLMLNFHLMF 334
 Score = 42.7 bits (100), Expect = 0.015
 Identities = 10/42 (23%), Positives = 21/42 (49%)

Query: 276 KKNILLLTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGY 317
           ++ + ++    + + +  I HKE RF+ P +P +L    R  
Sbjct: 434 RELLHIMPFFVWFLFWMSIAHKEERFMSPAYPFMLLAATRTL 475
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
          Length = 283

 Score =  108 bits (269), Expect = 2e-22
 Identities = 38/120 (31%), Positives = 59/120 (48%), Gaps = 11/120 (9%)

Query: 236 FNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKNILLLTGLFY-------I 288
           FNV  +  S  +G  PWY+YI   IP +L + +  +I GL    +    L         I
Sbjct: 131 FNVV-QGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYI 189

Query: 289 IGFSLIQHKEFRFIYPIHPILLYFTARGYV---KFKPKFVLLGILLNICIGLFFTNVHER 345
           I  SL+ HKE RF+ PI P+L  +    +    K++   + + I +NI I LF +  H++
Sbjct: 190 IVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRGSAMAVMIAINIGIALFTSRYHQK 249
 Score = 87.1 bits (214), Expect = 6e-16
 Identities = 28/81 (34%), Positives = 47/81 (57%), Gaps = 2/81 (2%)

Query: 8   SSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIHP 67
           ++ +L A + +FR  + + + ++F  DE +Q+ E AHH VYG G+L+WEW+  LRS  HP
Sbjct: 67  TTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHP 126

Query: 68  LIYVLGYKLVGDNTTLVCISP 88
            +      +V   + L  + P
Sbjct: 127 ALIAF--NVVQGGSALFGVHP 145
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
 gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
           [Caenorhabditis elegans]
          Length = 232

 Score =  103 bits (256), Expect = 8e-21
 Identities = 38/120 (31%), Positives = 59/120 (48%), Gaps = 11/120 (9%)

Query: 236 FNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKNILLLTGLFY-------I 288
           FNV  +  S  +G  PWY+YI   IP +L + +  +I GL    +    L         I
Sbjct: 67  FNVV-QGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYI 125

Query: 289 IGFSLIQHKEFRFIYPIHPILLYFTARGYV---KFKPKFVLLGILLNICIGLFFTNVHER 345
           I  SL+ HKE RF+ PI P+L  +    +    K++   + + I +NI I LF +  H++
Sbjct: 126 IVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRGSAMAVMIAINIGIALFTSRYHQK 185
 Score = 83.6 bits (205), Expect = 8e-15
 Identities = 28/81 (34%), Positives = 47/81 (57%), Gaps = 2/81 (2%)

Query: 8  SSYKLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSAIHP 67
          ++ +L A + +FR  + + + ++F  DE +Q+ E AHH VYG G+L+WEW+  LRS  HP
Sbjct: 3  TTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHP 62

Query: 68 LIYVLGYKLVGDNTTLVCISP 88
           +      +V   + L  + P
Sbjct: 63 ALIAF--NVVQGGSALFGVHP 81
>gb|AAL80168.1| (AE010131) hypothetical protein [Pyrococcus furiosus DSM 3638]
          Length = 461

 Score = 41.5 bits (97), Expect = 0.032
 Identities = 49/302 (16%), Positives = 105/302 (34%), Gaps = 34/302 (11%)

Query: 61  LRSAIHPLIYVLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDS-EKLAWIT 119
            R  ++P    L +K +         + ++I+ L   +     Y+   +     K   I 
Sbjct: 56  YRPPLYPYTLSLFFKFL--PYDFHLPASRIISLLFYTLTALLTYEIGKMLLGSRKFGIIA 113

Query: 120 LMLSLFNPFNWYVITRSFSNNLEMVFTVLALR--FWPWNKKINGSWYISLGFGFVSCIIR 177
            +L +FNP  + +  R+  ++    F  L++   +    +       +S  F  ++ + R
Sbjct: 114 SLLYVFNPLAFTMAKRTLVHSEFTFFFTLSMYLFYLGERENRELYTVLSFFFAGLTILAR 173

Query: 178 PTNILIWIPLGIWLLISIRIT----LKWVALSFLEVVLILLINTALDYFYQKLTFPLYNF 233
            T ++I     ++L ++         +++    + ++ +          Y     P    
Sbjct: 174 YTGLVILGVFVVYLYLTREWNWIKERRYIIGLLILLLTLSPWLYLGHLHYGGAFRPFK-- 231

Query: 234 LEFNVFYKNLSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGL-----KKNILLLTGLFYI 288
           +   V   +        P   + F  + +  + Y+PL +  L     K+N   L  L + 
Sbjct: 232 IASRVVTLDK-------PVSTFEFFELLVKDIGYIPLFLLALGIFFTKRNEKGLLVLSWF 284

Query: 289 IG----FSLIQHKEFRFIYPIHPILLYFTARGYV-------KFKPKFVLLGILLNICIGL 337
                    + HKE RFI    P +    A+G             K +  GI + + + L
Sbjct: 285 FVGLMGILTVTHKETRFITFTTPAMALIMAKGIQGVVEKTKNIPHKAIFEGIGVGVILIL 344

Query: 338 FF 339
            F
Sbjct: 345 LF 346
>ref|NP_214167.1| (NC_000918) hypothetical protein [Aquifex aeolicus]
 sp|O67601|YH04_AQUAE Hypothetical protein AQ_1704
 gb|AAC07577.1| (AE000752) hypothetical protein [Aquifex aeolicus]
          Length = 416

 Score = 41.1 bits (96), Expect = 0.045
 Identities = 45/306 (14%), Positives = 102/306 (32%), Gaps = 39/306 (12%)

Query: 61  LRSAIHPLIYVLGYKLVGDNTTLVCI-------------SPKVINALIAAIGEYNLYKFI 107
           LR+    + Y            L  +             S ++I+ L A      +Y   
Sbjct: 41  LRTGDFIVPYYNCNYRFEKPPMLYWLGSLSFLIFGISEFSARLISGLSAFGTTLLIYFIT 100

Query: 108 IVYDSEKLAWITLMLSLFNPFNWYVITRSFSNNLEMVFTVLALRFWPWNKKINGSWYISL 167
           + + S + A ++ +        W             +     L  + ++         +L
Sbjct: 101 LKHVSREKALLSALTFPLFIHTWIESRAYVPEF--TLVFFSTLGVYLFSIDRF-----TL 153

Query: 168 GFGFVSCIIRPTNIL-IWIPLGIWLLISIRITLKWVALSFLEVVLILLINTALDYFYQKL 226
           G+  ++        + + +P+GI+LL    +         L +++         +++  +
Sbjct: 154 GWTALALAFLTKGPVGVILPIGIYLLWRRDLKFLNFKGVLLFILIGF------SWYFLMI 207

Query: 227 TFPLYNFLEFNVFYKNLSIFYGTA-----PWYFYIFQAIPLMLMLYLPLMI-----YGLK 276
               +NF      ++N+  F GT      P YFY    + +  +L+LP+ +     +  +
Sbjct: 208 YKFGFNFFFKFFIFENIYRFTGTYQIHNMPIYFYPLVIL-VSSILFLPVFLKILKDFDKR 266

Query: 277 KNILLLTGLFYIIGFSLIQHKEFRFIYPIHPILLYFTARGYVKFKPKFVLLGILLNICIG 336
                   L  ++ +SL ++K   +I   +P L         K   K+  +     + + 
Sbjct: 267 LLPFAGWFLLVLVFYSLSKNKLHHYILFSYPALSVIIGFYLTKRYIKYAYIVGSF-LLLI 325

Query: 337 LFFTNV 342
           L F   
Sbjct: 326 LMFGVY 331
>ref|NP_542077.1| (NC_003318) MELITTIN RESISTANCE PROTEIN PQAB [Brucella melitensis]
 gb|AAL54341.1| (AE009741) MELITTIN RESISTANCE PROTEIN PQAB [Brucella melitensis]
          Length = 477

 Score = 37.6 bits (87), Expect = 0.46
 Identities = 38/291 (13%), Positives = 89/291 (30%), Gaps = 34/291 (11%)

Query: 11  KLFAFIFIFRLANSFAIETFFQADEFFQALEPAHHFVYGYGYLTWEWKQQLRSA----IH 66
                +   RL     +       E  +  E A   V    ++T ++   +       +H
Sbjct: 8   WGLFLLLFVRLLAMIWVPL-TDPTEA-RYAEIARKMVETGNWITPQFDYGVPFWAKPPLH 65

Query: 67  PLIYVLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFN 126
             +   G  + G        + ++   L +      L+++       + A I ++++  +
Sbjct: 66  TWLSAAGIAIFGTTAF----TARLGILLASLATLTILWQWACTLTDRRTATIAVLVA-AS 120

Query: 127 PFNWYVITRSFSNNLEMVFTVLAL---RFWPWNKKINGSWYISLGFGFVSCIIRPTNILI 183
              +YV       ++ +   V A     +          W   LG         P  +++
Sbjct: 121 SGLFYVSAAFVQTDMVLTLGVTASMAGFYNGLAGSRRWGWLFFLGLAIGLLAKGPVAVVL 180

Query: 184 WIPLGIWLLISIRITLKWVALSFLEVVLILLINTALDYFYQKLTFPLYNFLEFNVFYKNL 243
                   ++          L +   + +  +      +Y         FL++ +  +++
Sbjct: 181 SATPIAVWMLWRGNWRDLKHLPWAGGLTLCAVLVI--PWYAAAEIAPPGFLKYFLIGEHI 238

Query: 244 ---------SIFYG---TAP----WYFYIFQAIPLMLMLYLPLMIYGLKKN 278
                       YG          W F+I   +P      LP++I+ L+KN
Sbjct: 239 QRFLQPGWSGDLYGAGREHARGSIWLFWIVATLPWS--PLLPVLIWRLRKN 287
>ref|NP_298219.1| (NC_002488) conserved hypothetical protein [Xylella fastidiosa
           9a5c]
 pir||B82744 conserved hypothetical protein XF0929 [imported] - Xylella
           fastidiosa (strain 9a5c)
 gb|AAF83739.1|AE003932_3 (AE003932) conserved hypothetical protein [Xylella fastidiosa 9a5c]
          Length = 583

 Score = 37.6 bits (87), Expect = 0.52
 Identities = 40/274 (14%), Positives = 78/274 (27%), Gaps = 38/274 (13%)

Query: 68  LIYVLGYKLVGDNTTLVCISPKVINALIAAIGEYNLYKFIIVYDSEKLAWITLMLSLFNP 127
            +    Y L G+      + P ++ AL   +    +Y       + ++        LF  
Sbjct: 82  WLQAAFYTLFGNLKVA-FLLPSLLAALGTLVC---VYDLGRRLWTRRIGLYAAYALLFTL 137

Query: 128 FNWYVITRSFSNNLEMVFTVLALRFWPWNKKING--SWYISLGFGFVSCIIR----PTNI 181
              Y   R+  + L + F   A      +    G   W++   F      I        +
Sbjct: 138 HFTYQAKRAQIDALVVFFITFANYGLLRHLLFGGHWRWWVLGWFAAGLGTITKGVGALAL 197

Query: 182 LIWIPLGIWLLISIRITLKWVALSFLEVVLILLINTALDYFYQKLTFPLYN--------- 232
           LI +P     L         V      +  +  +      +   +     +         
Sbjct: 198 LIVLPAAAASLAGWPRVRVHVRDVRFWLGPLGFLVAV-SLWLVPMVMTALSAQQPEYRAY 256

Query: 233 ---FLEFNVFYKN-LSIFYGTAPWYFYIFQAIPLMLMLYLPLMIYGLKKNIL-------- 280
               L    F +   S  +   PW  Y  Q + +M +  L  + + L             
Sbjct: 257 LNDILLRQTFGRYTKSWDHAQPPW--YFLQVMLVMWIPTLLALPWALPAWWRRLRRRDPR 314

Query: 281 ----LLTGLFYIIGFSLIQHKEFRFIYPIHPILL 310
               L   +  ++ FS+   K   +I P  P++ 
Sbjct: 315 YLLPLAWCVLLLVFFSIPSGKRDVYILPALPMVC 348
CPU time:   161.00 user secs.	    2.77 sys. secs	  163.77 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.315    0.183    0.519 

Gapped
Lambda     K      H
   0.270   0.0642    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 371271565
Number of Sequences: 887402
Number of extensions: 21430551
Number of successful extensions: 94400
Number of sequences better than 10.0: 1091
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 1041
Number of HSP's that attempted gapping in prelim test: 92932
Number of HSP's gapped (non-prelim): 1953
length of query: 482
length of database: 277,845,442
effective HSP length: 49
effective length of query: 433
effective length of database: 234,362,744
effective search space: 101479068152
effective search space used: 101479068152
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.6 bits)
S2: 76 (33.6 bits)