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GPI Anchor Biosynthesis Report: BAB32949.1 (PIG-B family, Oryza sativa)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (506 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 3

Distribution of 56 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 548 e-155
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 547 e-154
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 527 e-148
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 497 e-139
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 489 e-137
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 489 e-137
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 409 e-113
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 372 e-102
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 370 e-101
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 367 e-100
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 366 e-100
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 362 7e-99
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 359 6e-98
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 358 9e-98
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 316 6e-85
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 300 3e-80
emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus mus... 299 9e-80
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 298 2e-79
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 294 3e-78
ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo ... 286 6e-76
emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-... 285 1e-75
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 284 3e-75
gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melano... 283 4e-75
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 269 6e-71
pir||T39659 cell wall biosynthesis protein N3265 homolog - fissi... 246 5e-64
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 238 1e-61
ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Sacch... 232 9e-60
ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans] ... 231 3e-59
pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans 224 2e-57
gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan ... 219 8e-56
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 218 2e-55
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 215 1e-54
ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. ... 212 1e-53
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 210 4e-53
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 210 4e-53
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 181 3e-44
ref|NP_488731.1| (NC_003272) unknown protein [Nostoc sp. PCC 712... 171 2e-41
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 162 2e-38
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 147 3e-34
gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protei... 146 7e-34
gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 131 3e-29
dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharom... 130 5e-29
pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans 127 5e-28
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 123 7e-27
ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]... 120 5e-26
Alignments
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase -like protein [Arabidopsis
           thaliana]
 gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
          Length = 548

 Score =  548 bits (1398), Expect = e-155
 Identities = 280/530 (52%), Positives = 357/530 (66%), Gaps = 35/530 (6%)

Query: 1   MSHRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANA 60
           M  R+R+NA          G +   + + G+E PD  +   +GS RR+    LAFR  NA
Sbjct: 1   MDIRKRKNAG-----GDGDGGADGASVNVGDE-PD-SFGGRIGSPRRIFLFCLAFRVVNA 53

Query: 61  LLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDS 120
           LL++TYFNPDEHWQ LEVAHR +FGYG++TWEWKRG+RSYLHP +FA LYK+L +  LD+
Sbjct: 54  LLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDT 113

Query: 121 PWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGN 180
           P+ M  APRL+QS+F++ GDLYLYKLS  ++  +VA       +   + +F    +    
Sbjct: 114 PYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNC 173

Query: 181 SVVSKQQAASKQ----------SPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMK 230
                                  P +RK  L+IAALACAIRPTSA+ WLYVG+L+     
Sbjct: 174 LETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTP 233

Query: 231 SKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWY 290
           +K +FI LEV+P+G  VL  T  LD  MYGS +IVPLNFLKFN  SSGGDYYGTH +HWY
Sbjct: 234 NKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWY 293

Query: 291 FSQGFPSMIWTFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMF 350
           F+QGF  M++TF PFSI+GI+KS+  +L+ LI+WVL +YSILGHKEFRFVLPVLP   +F
Sbjct: 294 FTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIF 353

Query: 351 SGHNLAAM--------------AQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLY 396
           SG+  A M               Q+  + H +     +L+LSV  L+ TN+PMALYMSL+
Sbjct: 354 SGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWS--PKLRLSVYFLLATNIPMALYMSLF 411

Query: 397 HQRGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLPMRFLDCTPSENKGTLD 456
           HQRGTEDAM YLS EA+ GRVKS+LFLMPCHSTPYYSTLH N+PM+FLDCTPS  KG LD
Sbjct: 412 HQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELD 471

Query: 457 ESDRFLMNPADFVGEVFGNLSS-FSHIVLFESEERHVK-LLLRNSFQEVK 504
           ESD+FL+NP  F  E+  N S   SHIVLF SEE  ++  ++++SF+EV+
Sbjct: 472 ESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVR 521
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
 dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
          Length = 506

 Score =  547 bits (1397), Expect = e-154
 Identities = 506/506 (100%), Positives = 506/506 (100%)

Query: 1   MSHRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANA 60
           MSHRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANA
Sbjct: 1   MSHRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANA 60

Query: 61  LLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDS 120
           LLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDS
Sbjct: 61  LLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDS 120

Query: 121 PWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGN 180
           PWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGN
Sbjct: 121 PWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGN 180

Query: 181 SVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEV 240
           SVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEV
Sbjct: 181 SVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEV 240

Query: 241 VPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIW 300
           VPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIW
Sbjct: 241 VPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIW 300

Query: 301 TFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQ 360
           TFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQ
Sbjct: 301 TFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQ 360

Query: 361 LKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV 420
           LKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV
Sbjct: 361 LKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV 420

Query: 421 LFLMPCHSTPYYSTLHYNLPMRFLDCTPSENKGTLDESDRFLMNPADFVGEVFGNLSSFS 480
           LFLMPCHSTPYYSTLHYNLPMRFLDCTPSENKGTLDESDRFLMNPADFVGEVFGNLSSFS
Sbjct: 421 LFLMPCHSTPYYSTLHYNLPMRFLDCTPSENKGTLDESDRFLMNPADFVGEVFGNLSSFS 480

Query: 481 HIVLFESEERHVKLLLRNSFQEVKHC 506
           HIVLFESEERHVKLLLRNSFQEVKHC
Sbjct: 481 HIVLFESEERHVKLLLRNSFQEVKHC 506
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein - Arabidopsis
           thaliana
 emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein [Arabidopsis
           thaliana]
          Length = 498

 Score =  527 bits (1345), Expect = e-148
 Identities = 288/518 (55%), Positives = 362/518 (69%), Gaps = 38/518 (7%)

Query: 1   MSHRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANA 60
           M  R+R+NA          G +   + + G+E PD  +   +GS RR+    LAFR  NA
Sbjct: 1   MDIRKRKNAG-----GDGDGGADGASVNVGDE-PD-SFGGRIGSPRRIFLFCLAFRVVNA 53

Query: 61  LLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDS 120
           LL++TYFNPDEHWQ LEVAHR +FGYG++TWEWKRG+RSYLHP +FA LYK+L +  LD+
Sbjct: 54  LLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDT 113

Query: 121 PWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGN 180
           P+ M  APRL+QS+F++ GDLYLYKLS  ++  +VA   TVLT+ GLYYW    +S    
Sbjct: 114 PYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSTVLTIMGLYYWPCIRDSSID- 172

Query: 181 SVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEV 240
                        P +RK  L+IAALACAIRPTSA+ WLYVG+L+     +K +FI LEV
Sbjct: 173 ------------YPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEV 220

Query: 241 VPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIW 300
           +P+G  VL  T  LD  MYGS +IVPLNFLKFN  SSGGDYYGTH +HWYF+QGF  M++
Sbjct: 221 IPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLF 280

Query: 301 TFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAM-- 358
           TF PFSI+GI+KS+  +L+ LI+WVL +YSILGHKEFRFVLPVLP   +FSG+  A M  
Sbjct: 281 TFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEV 340

Query: 359 ------------AQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAML 406
                        Q+  + H +     +L+LSV  L+ TN+PMALYMSL+HQRGTEDAM 
Sbjct: 341 SGSSSSSSVTKKKQVPRQNHTKWS--PKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMN 398

Query: 407 YLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLPMRFLDCTPSENKGTLDESDRFLMNPA 466
           YLS EA+ GRVKS+LFLMPCHSTPYYSTLH N+PM+FLDCTPS  KG LDESD+FL+NP 
Sbjct: 399 YLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNPL 458

Query: 467 DFVGEVFGNLSS-FSHIVLFESEERHVK-LLLRNSFQE 502
            F  E+  N S   SHIVLF SEE  ++  ++++SF+E
Sbjct: 459 GFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKE 496
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
           GPI-anchor biosynthesis [Mus musculus]
 dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
          Length = 542

 Score =  497 bits (1267), Expect = e-139
 Identities = 186/506 (36%), Positives = 267/506 (52%), Gaps = 29/506 (5%)

Query: 7   RNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANALLVRTY 66
           RN  G      +    + +  S  E+R   P    LG    ++   +A R  N  LV+T 
Sbjct: 13  RNLHGSSGEMKLRRRKSRQYVSAQEKRS--PRRGLLGENTYLVLFTIALRILNCFLVQTS 70

Query: 67  FNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDSPWFMAM 126
           F PDE+WQ LEVAHR+VF YG+LTWEW   LR Y +P IFA++YK+L LL  DS  F+  
Sbjct: 71  FVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLHLLGKDSVQFLIW 130

Query: 127 APRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNSVVSKQ 186
            PRL Q++ ++  D+ LY L K + N  VA    +  +   + W+    ++      S  
Sbjct: 131 IPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLT 190

Query: 187 QAASKQSP------PSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEV 240
             A    P       +     L+ ALAC +RPT+ I W+ +    F Q + K        
Sbjct: 191 ALALFYYPLEGSRSVNSIKYSLLVALACVVRPTALIPWVPLLFRHFYQEQRKLHLTLHHF 250

Query: 241 VPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIW 300
           +P+G    +++  +D   +G   +V LNFLKFN+  + G +YG+H +HWY SQGFP ++ 
Sbjct: 251 LPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPVVLG 310

Query: 301 TFLPFSISGI-LKSREWRL-AGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAM 358
           T LPF I G  L  R   +    ++W L+VYS+LGHKEFRF+ PVLPF  +F G++LA +
Sbjct: 311 THLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSLAHL 370

Query: 359 AQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREA---HDG 415
              +             K ++  L+L+NVP+A Y  L HQRGT D M ++ +      D 
Sbjct: 371 KTWR-------------KAALSFLLLSNVPLAFYTGLVHQRGTLDVMNHIQKVCPRGPDP 417

Query: 416 RVKSVLFLMPCHSTPYYSTLHYNLPMRFLDCTPSENKG--TLDESDRFLMNPADFVGEVF 473
              SV  +MPCHSTPYYS +H  L MRFL C P        LDE+D F +NP  ++ + F
Sbjct: 418 ASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEADMFYLNPLRWLQQEF 477

Query: 474 G-NLSSFSHIVLFESEERHVKLLLRN 498
             N S  +H+V F   E+ +   L +
Sbjct: 478 HSNASLPTHLVTFNVLEKEINTFLTS 503
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
          Length = 554

 Score =  489 bits (1248), Expect = e-137
 Identities = 179/500 (35%), Positives = 260/500 (51%), Gaps = 28/500 (5%)

Query: 14  PPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANALLVRTYFNPDEHW 73
               +    +    +T +E+        LG    +L   LA R  N  LV+T F PDE+W
Sbjct: 30  GKIKLRKRKSTLYFNT-QEKSARRRGDLLGENIYLLLFTLALRILNCFLVQTSFVPDEYW 88

Query: 74  QCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDSPWFMAMAPRLLQS 133
           Q LEV+H +VF YG+LTWEW   LRSY +P IFA++YKIL LL  DS   +   PRL Q+
Sbjct: 89  QSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQA 148

Query: 134 VFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQS 193
           + ++  D+ LY L K + N  VA       +   + W+    ++           A    
Sbjct: 149 LLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYY 208

Query: 194 PP------SRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFV 247
           P       +      + ALA  IRPT+ I W  +    F Q   K   I    +P+G   
Sbjct: 209 PLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVT 268

Query: 248 LAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSI 307
           L+++  +D   +G   +V  NFLKFN+  + G +YG+H +HWYFSQGFP ++ T LPF I
Sbjct: 269 LSLSLMIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPVILGTHLPFFI 328

Query: 308 SGI-LKSREWRL-AGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKG 365
            G  L  + +R+    ++W L+VYS+L HKEFRF+ PVLPF  +F G++L  +   K   
Sbjct: 329 HGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWK--- 385

Query: 366 HNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVK---SVLF 422
                     K ++  L L+N+ +ALY  L HQRGT D M ++ +  ++   K   S+  
Sbjct: 386 ----------KPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFI 435

Query: 423 LMPCHSTPYYSTLHYNLPMRFLDCTPSE--NKGTLDESDRFLMNPADFVGEVFGNLSS-F 479
           +MPCHSTPYYS +H  LPMRFL C P        LDE+D F +NP ++    F + +S  
Sbjct: 436 MMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWSHREFHDDASLP 495

Query: 480 SHIVLFESEERHVKLLLRNS 499
           +H++ F   E  +   L +S
Sbjct: 496 THLITFSILEEEISAFLISS 515
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
 pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
           (EC 2.4.1.130) PIGB - human
 dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
          Length = 554

 Score =  489 bits (1247), Expect = e-137
 Identities = 178/500 (35%), Positives = 261/500 (51%), Gaps = 28/500 (5%)

Query: 14  PPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANALLVRTYFNPDEHW 73
               +    +    +T +E+        LG    +L   +A R  N  LV+T F PDE+W
Sbjct: 30  GKIKLRKRKSTLYFNT-QEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSFVPDEYW 88

Query: 74  QCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDSPWFMAMAPRLLQS 133
           Q LEV+H +VF YG+LTWEW   LRSY +P IFA++YKIL LL  DS   +   PRL Q+
Sbjct: 89  QSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWIPRLAQA 148

Query: 134 VFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQS 193
           + ++  D+ LY L K + N  VA       +   + W+    ++           A    
Sbjct: 149 LLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIALFYY 208

Query: 194 PP------SRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFV 247
           P       +      + ALA  IRPT+ I W  +    F Q   K   I    +P+G   
Sbjct: 209 PLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLILHHFLPVGFVT 268

Query: 248 LAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSI 307
           L+++  +D   +G   +V  NFLKFN+  + G +YG+H +HWYFSQGFP ++ T LPF I
Sbjct: 269 LSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPVILGTHLPFFI 328

Query: 308 SGI-LKSREWRL-AGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKG 365
            G  L  + +R+    ++W L+VYS+L HKEFRF+ PVLPF  +F G++L  +   K   
Sbjct: 329 HGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWK--- 385

Query: 366 HNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVK---SVLF 422
                     K ++  L L+N+ +ALY  L HQRGT D M ++ +  ++   K   S+  
Sbjct: 386 ----------KPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNPNKSSASIFI 435

Query: 423 LMPCHSTPYYSTLHYNLPMRFLDCTPSE--NKGTLDESDRFLMNPADFVGEVFGNLSS-F 479
           +MPCHSTPYYS +H  LPMRFL C P        LDE+D F +NP +++   F + +S  
Sbjct: 436 MMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEADVFYLNPLNWLHREFHDDASLP 495

Query: 480 SHIVLFESEERHVKLLLRNS 499
           +H++ F   E  +   L +S
Sbjct: 496 THLITFSILEEEISAFLISS 515
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
          Length = 512

 Score =  409 bits (1042), Expect = e-113
 Identities = 155/474 (32%), Positives = 240/474 (49%), Gaps = 54/474 (11%)

Query: 46  RRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFI 105
             V  L LA R A+  +V+TY+ PDE+WQ LEVAH++ FGYG+LTWEW +G+RSY++P +
Sbjct: 4   IYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLL 63

Query: 106 FAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVT 165
            A LYKIL+LL LDS   + + PR+ +                             L + 
Sbjct: 64  IAGLYKILALLQLDSAHLLVVLPRIRK-------------------------WALFLILV 98

Query: 166 GLYYWFVAIESVKGNSVVSKQQAASKQSP--PSRKMALLIAALACAIRPTSAITWLYVGL 223
             ++++    ++      S    A    P        L  AA+ C +RPT+A+ WL + L
Sbjct: 99  PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSL 158

Query: 224 LDFIQMKSKS-RFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYY 282
               + +      I    V +G+ V  +   +D + +G  I+ P  FLK+N+F++ G +Y
Sbjct: 159 YHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFY 218

Query: 283 GTHVFHWYFSQGFPSMIWTFLPFSISGIL--------KSREWRLAGLIVWVLVVYSILGH 334
           G+H +HWYFS G P+++       I G++             +L   I   LVV S + H
Sbjct: 219 GSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEH 278

Query: 335 KEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMS 394
           KEFRFV P+LP         L+  +         +   + L  + +++++ NV  A Y+S
Sbjct: 279 KEFRFVSPLLPLCLYVITDALSRWSI--------RASSTMLWTTALVILVGNVMPAWYLS 330

Query: 395 LYHQRGTEDAMLYL---SREAHDGR--VKSVLFLMPCHSTPYYSTLHYNLPMRFLDCTPS 449
             HQ+G  + M  L   +RE  D R    ++LFLMPCHSTPYYS +H N+ MRFL C P+
Sbjct: 331 TVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPN 390

Query: 450 ENKGTL--DESDRFLMNPADFVGE--VFGNLSS-FSHIVLFESEERHVKLLLRN 498
             K     DE+DRF  +P  ++        L++  +H+VLF+    ++ + LRN
Sbjct: 391 LEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLRN 444
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
          Length = 611

 Score =  372 bits (947), Expect = e-102
 Identities = 97/459 (21%), Positives = 163/459 (35%), Gaps = 52/459 (11%)

Query: 5   RRRNAA---GPPPPEGIG-----GSSTAEASSTGEERPDLPWAWALGSERRVLALALAFR 56
           R + +    G   P         GS  A  +    E            E       L   
Sbjct: 9   RLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGSTAFKCLLSA 68

Query: 57  AANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAAL----Y 110
              A L+    + DE +   E  H +++G G  TWE+     +RSY +  + A       
Sbjct: 69  RLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHA 128

Query: 111 KILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTV--TGLY 168
           +IL    +   +F+    R L +  +   +LY YK     F  HV+ M     V  TG++
Sbjct: 129 RILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMF 184

Query: 169 YWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQ 228
               A          +           +    L +AA A    P SA   L +   D + 
Sbjct: 185 CSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIA-FDLLV 243

Query: 229 MKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFS-SGGDYYGTHVF 287
           MK + +  F   +   +  L     +D + YG  +I PLN + +N+F+  G D YGT  +
Sbjct: 244 MKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPW 303

Query: 288 HWYFSQGFPSMIWTFLP-----------------FSISGILKSREWRLAGLIVWVLVVYS 330
           ++Y   GF +    F                   F +  +       LA + +W ++ + 
Sbjct: 304 YFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF- 362

Query: 331 ILGHKEFRFVLPVLPFMFMFSGHNLAAM--------AQLKGKGHNEKGRLSRLKLSVIL- 381
           I  HKE RF+ PV P + +     L+A+         + + + +        L    +  
Sbjct: 363 IQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFG 422

Query: 382 LILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV 420
           L+  +  +AL+       G  D      R A D  + +V
Sbjct: 423 LLSFSRSVALFRG---YHGPLDLYPEFYRIATDPTIHTV 458
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
          Length = 611

 Score =  370 bits (941), Expect = e-101
 Identities = 97/459 (21%), Positives = 164/459 (35%), Gaps = 52/459 (11%)

Query: 5   RRRNAA---GPPPPEGIG-----GSSTAEASSTGEERPDLPWAWALGSERRVLALALAFR 56
           R + +    G   P         GS  A  +    E            E       L   
Sbjct: 9   RLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGSTAFKCLLSA 68

Query: 57  AANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAAL----Y 110
              A L+    + DE +   E  H +++G G  TWE+     +RSY +  + A       
Sbjct: 69  RLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHA 128

Query: 111 KILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTV--TGLY 168
           +IL    +   +F+    R L +  +   +LY YK     F  HV+ M     V  TG++
Sbjct: 129 RILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMF 184

Query: 169 YWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQ 228
               A          +           +    L +AA A    P SA   L +   D + 
Sbjct: 185 CSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIA-FDLLV 243

Query: 229 MKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFS-SGGDYYGTHVF 287
           MK + +  F   +   +  L     +D + YG  +I PLN + +N+F+  G D YGT  +
Sbjct: 244 MKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPW 303

Query: 288 HWYFSQGFPSMIWTFLP-----------------FSISGILKSREWRLAGLIVWVLVVYS 330
           ++Y  +GF +    F                   F +  +       LA + +W ++ + 
Sbjct: 304 YFYLIKGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF- 362

Query: 331 ILGHKEFRFVLPVLPFMFMFSGHNLAAM--------AQLKGKGHNEKGRLSRLKLSVIL- 381
           I  HKE RF+ PV P + +     L+A+         + + + +        L    +  
Sbjct: 363 IQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFG 422

Query: 382 LILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV 420
           L+  +  +AL+       G  D      R A D  + +V
Sbjct: 423 LLSFSRSVALFRG---YHGPLDLYPEFYRIATDPTIHTV 458
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
          Length = 618

 Score =  367 bits (935), Expect = e-100
 Identities = 97/466 (20%), Positives = 163/466 (34%), Gaps = 59/466 (12%)

Query: 5   RRRNAA---GPPPPEGIG-----GSSTAEASSTGEERPDLPWAWALGSERRVLALALAFR 56
           R + +    G   P         GS  A  +    E            E       L   
Sbjct: 9   RLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGSTAFKCLLSA 68

Query: 57  AANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAAL----Y 110
              A L+    + DE +   E  H +++G G  TWE+     +RSY +  + A       
Sbjct: 69  RLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHA 128

Query: 111 KILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTV--TGLY 168
           +IL    +   +F+    R L +  +   +LY YK     F  HV+ M     V  TG++
Sbjct: 129 RILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMF 184

Query: 169 YWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQ 228
               A          +           +    L +AA A    P SA   L +   D + 
Sbjct: 185 CSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIA-FDLLV 243

Query: 229 MKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFS-SGGDYYGTHVF 287
           MK + +  F   +   +  L     +D + YG  +I PLN + +N+F+  G D YGT  +
Sbjct: 244 MKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPW 303

Query: 288 HWYFSQGFPSMIWTFLP-----------------FSISGILKSREWRLAGLIVWVLVVYS 330
           ++Y   GF +    F                   F +  +       LA + +W ++ + 
Sbjct: 304 YFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF- 362

Query: 331 ILGHKEFRFVLPVLPFMFMFSGHNLAAM---------------AQLKGKGHNEKGRLSRL 375
           I  HKE RF+ PV P + +     L+A+                + + + +        L
Sbjct: 363 IQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLAL 422

Query: 376 KLSVIL-LILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV 420
               +  L+  +  +AL+       G  D      R A D  + +V
Sbjct: 423 GTVFLFGLLSFSRSVALFRG---YHGPLDLYPEFYRIATDPTIHTV 465
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
           mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
 dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
          Length = 618

 Score =  366 bits (931), Expect = e-100
 Identities = 97/466 (20%), Positives = 163/466 (34%), Gaps = 59/466 (12%)

Query: 5   RRRNAA---GPPPPEGIG-----GSSTAEASSTGEERPDLPWAWALGSERRVLALALAFR 56
           R + +    G   P         GS  A  +    E            E       L   
Sbjct: 9   RLKGSGASSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGSTAFKCLLSA 68

Query: 57  AANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAAL----Y 110
              A L+    + DE +   E  H +++G G  TWE+     +RSY +  + A       
Sbjct: 69  RLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHA 128

Query: 111 KILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTV--TGLY 168
           +IL    +   +F+    R L +  +   +LY YK     F  HV+ M     V  TG++
Sbjct: 129 RILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMF 184

Query: 169 YWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQ 228
               A          +           +    L +AA A    P SA   L +   D + 
Sbjct: 185 CSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIA-FDLLV 243

Query: 229 MKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFS-SGGDYYGTHVF 287
           MK + +  F   +   +  L     +D + YG  +I PLN + +N+F+  G D YGT  +
Sbjct: 244 MKHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNIFTPHGPDLYGTEPW 303

Query: 288 HWYFSQGFPSMIWTFLP-----------------FSISGILKSREWRLAGLIVWVLVVYS 330
           ++Y   GF +    F                   F +  +       LA + +W ++ + 
Sbjct: 304 YFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF- 362

Query: 331 ILGHKEFRFVLPVLPFMFMFSGHNLAAM---------------AQLKGKGHNEKGRLSRL 375
           I  HKE RF+ PV P + +     L+A+                + + + +        L
Sbjct: 363 IQPHKEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLAL 422

Query: 376 KLSVIL-LILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV 420
               +  L+  +  +AL+       G  D      R A D  + +V
Sbjct: 423 GTVFLFGLLSFSRSVALFRG---YHGPLDLYPEFYRIATDPTIHTV 465
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
           [Schizosaccharomyces pombe]
          Length = 506

 Score =  362 bits (922), Expect = 7e-99
 Identities = 144/485 (29%), Positives = 226/485 (45%), Gaps = 63/485 (12%)

Query: 45  ERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPF 104
                   L FR  NAL V+T+F PDE +Q LEVAH  +F YG LTWEW   +RS LHP 
Sbjct: 2   RIWFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHPL 61

Query: 105 IFAALYKILSLLHLDSPWFMA-MAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLT 163
           IFAALY++L +L LDS +F+   AP+LLQ  FA+  D   YK + + + +  A+     +
Sbjct: 62  IFAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKTANWTLACS 121

Query: 164 VTGLYYWFVAIESVKGNSVVSKQQAASKQS----------PPSRKM-------ALLIAAL 206
           +  +   +V + +   +   +                   P  RK         + +AA 
Sbjct: 122 LVSIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAF 181

Query: 207 ACAIRPTSAITWLYVGLLD-------------FIQMKSKSRFIFLE--VVPLGVFVLAVT 251
           AC IRPT+ + W++  L               F  + ++ RF++        G+FVL V+
Sbjct: 182 ACFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVS 241

Query: 252 TFL-----DCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFS 306
            FL     D  +YG  +   ++F +FN+ S     YG + +H+Y SQ  P +   FLPF 
Sbjct: 242 LFLVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPF- 300

Query: 307 ISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGH 366
              +L + + + AG I+ V   YS++GHKE RFV P+ P +   +G   ++ +  K    
Sbjct: 301 ---VLLTMDLQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFFSSFSSWKRAAR 357

Query: 367 NEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPC 426
                         L+ L +  +  ++  +HQ G  + M  +   A   +  + L L PC
Sbjct: 358 FF-----------FLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKNQ--TGLILAPC 404

Query: 427 HSTPYYSTLHYNLP---MRFLDCTPSENKGTLDESDRFLMNPADFVGEVFGNLSSFSHIV 483
           H+TP+ S +H        +FL C P E     DE+DRF  N   F+ ++        +++
Sbjct: 405 HTTPWQSHIHSPFAENGWKFLTCEPFEKP--FDETDRFYENMPTFLDKI---KEWPDYLI 459

Query: 484 LFESE 488
            FE  
Sbjct: 460 FFEER 464
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
          Length = 558

 Score =  359 bits (913), Expect = 6e-98
 Identities = 119/506 (23%), Positives = 205/506 (39%), Gaps = 78/506 (15%)

Query: 45  ERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPF 104
              +++L   +R      +RT   PDE WQ  EVA+ +VFG GHL WEW+ GLRS L P 
Sbjct: 2   PWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPA 61

Query: 105 IFAALYKILSLLHLDSPWFMAMAPRLLQSV------------------------------ 134
           + A  + +L LL  D+ W +  APR+LQ++                              
Sbjct: 62  VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121

Query: 135 --------FASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNSVVSKQ 186
                   F+ F ++ + +  + I N+ +++   +L+++  Y  +  +            
Sbjct: 122 TRQSKTKGFSYFCEVSVSRSRRGICNS-ISYTALLLSLSNWYMAYCGVRLYGNVIEALLV 180

Query: 187 QAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFI--FLEVVPLG 244
                         LL+  LA AIR TSA+    +          +  FI     +V  G
Sbjct: 181 LLT--LQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTG 238

Query: 245 VFVLAV----TTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIW 300
           + VL         LD   YG  ++ PL F +FN+  +   ++G H +++Y       ++ 
Sbjct: 239 LIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVG 298

Query: 301 TFLPFSISGILKSRE-----------WRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFM 349
             + F+I+  L                 + G+  W L  YS++ HKE RFV  V+P   +
Sbjct: 299 PHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLI 358

Query: 350 FSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLS 409
            +   L   ++            + +     L +L N+ M   M   ++RG  D M    
Sbjct: 359 TAAFVLVRWSR----------TSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVM---- 404

Query: 410 REAHD-GRVKSVLFLMPCHSTPYYSTLHYNLP-MRFLDCTPSENKGT----LDESDRFLM 463
            E  D  R+  +  +  C++ P YS +H  +  + F+DC+   ++ T    + E   F  
Sbjct: 405 AEVRDGPRINRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRR 464

Query: 464 NPADFVGEVFGNLSSFSHIVLFESEE 489
            P ++V   +    SF+   L ES +
Sbjct: 465 YPKEYVLWRYDGKHSFNMSDLEESRK 490
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
           musculus]
          Length = 611

 Score =  358 bits (912), Expect = 9e-98
 Identities = 98/467 (20%), Positives = 162/467 (33%), Gaps = 56/467 (11%)

Query: 1   MSHRRRR----------NAAGPPPPEGIGGSSTAEASSTGEERP--DLPWAWALGSERRV 48
           M+ RR R             G   P            +  E RP            E   
Sbjct: 1   MASRRARQRLKGGGGGGGGGGDAGPAAEKLEQLGSREAGAEPRPESGNKAGQVWAPEGST 60

Query: 49  LALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIF 106
               L      A L+    + DE +   E  H +++G G  TWE+     +RSY +  + 
Sbjct: 61  AFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLH 120

Query: 107 AAL----YKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVL 162
           A       +IL    +   +F+    R L +  +   +LY YK     F  HV+ M    
Sbjct: 121 AWPAAFHARILQTNKILVFYFL----RCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAF 176

Query: 163 TV--TGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLY 220
            V  TG++    A          +           +    L +AA A    P SA   L 
Sbjct: 177 LVLSTGMFCSSSAFLPSSFCMYTTLIAMTGWYMDKTPIAVLGVAAGAILGWPFSAALGLP 236

Query: 221 VGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLF-SSGG 279
           +   D +  K + +   L  +      L     +D + YG  ++ PLN + +N+F S G 
Sbjct: 237 IA-FDLLARKHRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVLYNVFTSHGP 295

Query: 280 DYYGTHVFHWYFSQGFPSMIWTFLP-----------------FSISGILKSREWRLAGLI 322
           D YGT  +++Y   GF +    F                   F +  +       LA + 
Sbjct: 296 DLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMY 355

Query: 323 VWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAM--------AQLKGKGHNEKGRLSR 374
           +W ++ + I  HKE RF+ PV P + +     L+A+         + + + +        
Sbjct: 356 IWFIIFF-IQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVFQRYRLEHYTVTSNWLA 414

Query: 375 LKLSVIL-LILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSV 420
           L    +  L+  +  +AL+       G  D      R A D  + +V
Sbjct: 415 LGTVFLFGLLSFSRSVALFRG---YHGPLDLYPEFYRIATDPTIHTV 458
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
 gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
 gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
          Length = 623

 Score =  316 bits (803), Expect = 6e-85
 Identities = 85/438 (19%), Positives = 157/438 (35%), Gaps = 37/438 (8%)

Query: 5   RRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANALLVR 64
           + + A      +        + +S G+E+  LP    + S +      ++ R  +A+   
Sbjct: 35  KTKEATPAGKKKDKDAKKRNQPTSGGQEK-GLPNP-IMPSVQTAFKTFVSARLCSAIW-A 91

Query: 65  TYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAALYKILSLLHLDSPW 122
              + DE +   E  H I+ G+G  TWE+    GLRSY +  +          L   SP 
Sbjct: 92  YIADCDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPGYFYQKLFNPSPI 151

Query: 123 FMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTV--TGLYYWFVAIESVKGN 180
            +    R +     +  + Y+YK     F  H+  +  +  +   G++    A+     +
Sbjct: 152 LIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFS 211

Query: 181 SVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEV 240
                   A+           L A  A    P +A+  + + L   ++ +    F+    
Sbjct: 212 MYFGCAALAAWWQQNYCFAIFLTAISALLGWPFAALIGIPLVLEMLLRQRDWKTFV-QWT 270

Query: 241 VPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLF-SSGGDYYGTHVFHWYFSQGFPSMI 299
           +  G  V      +D   +G     PLN + +N+F S G + +GT    +Y   GF +  
Sbjct: 271 LISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNFN 330

Query: 300 WTFLP---FSISGILK--------------SREWRLAGLIVWVLVVYSILGHKEFRFVLP 342
             +L      I  ++                    LA L +W+LV +    HKE RF+ P
Sbjct: 331 IIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFF-AQPHKEERFLFP 389

Query: 343 VLPFMFMFSGHN-------LAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMAL---Y 392
           + P + +               M  +  K       L       IL+++T+  + L   +
Sbjct: 390 IYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRVF 449

Query: 393 MSLYHQRGTEDAMLYLSR 410
               +     D ML L++
Sbjct: 450 ALYRNYHAPMDLMLELNQ 467
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
 sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
 pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
 emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
           (Swiss Prot accession number P38376)~cDNA EST yk549e12.3
           comes from this gene~cDNA EST yk618d6.3 comes from this
           gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
           yk618d6.5 comes from>
          Length = 653

 Score =  300 bits (763), Expect = 3e-80
 Identities = 85/454 (18%), Positives = 151/454 (32%), Gaps = 45/454 (9%)

Query: 1   MSHRRRRNAAGPPPP-----------EGIGGSSTAEASSTGEERPDLPWAWALGSERRVL 49
           M   RR+  +GPP             +        E        PD  W ++ GS   V 
Sbjct: 1   MVTHRRKGGSGPPQKPPPRIVDRSSFDADKKKIKVEKLYHKANNPDNDWPFSFGS---VF 57

Query: 50  ALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFA 107
            + L+ R + A+      + DE +   E  H  ++G G  TWE+     +RSY + ++  
Sbjct: 58  KMLLSIRISGAIWGI-INDCDEVYNYWEPLHLFLYGEGFQTWEYSPVYAIRSYFYIYLHY 116

Query: 108 ALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVL--TVT 165
               + + L  D+   +    RL   +F   G+ Y +       N        +     +
Sbjct: 117 IPASLFANLFGDTKIVVFTLIRLTIGLFCLLGEYYAFDAICKKINIATGRFFILFSIFSS 176

Query: 166 GLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLD 225
           G++    A         ++     +  +         +A       P SA+  L +    
Sbjct: 177 GMFLASTAFVPSSFCMAITFYILGAYLNENWTAGIFCVAFSTMVGWPFSAVLGLPIVADM 236

Query: 226 FIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSS-GGDYYGT 284
            +    + RFI    + +G+ +  V    D   +G  ++ PLN   +N+ S  G   YG 
Sbjct: 237 LLLKGLRIRFILT-SLVIGLCIGGVQVITDSHYFGKTVLAPLNIFLYNVVSGPGPSLYGE 295

Query: 285 HVFHWYFSQGFPSMIWTFL--PFSISGILK-------------------SREWRLAGLIV 323
               +Y    F +        PF     L                    +    LA    
Sbjct: 296 EPLSFYIKNLFNNWNIVIFAAPFGFPLSLAYFTKVWMSQDRNVALYQRFAPIILLAVTTA 355

Query: 324 WVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLI 383
             L+++    HKE RF+ P+ PF+  F+   L A  +L  K       LS L +    ++
Sbjct: 356 AWLLIFGSQAHKEERFLFPIYPFIAFFAALALDATNRLCLKKLGMDNILSILFILCFAIL 415

Query: 384 LTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRV 417
             +     Y    +     +    L+ E  +   
Sbjct: 416 SASR---TYSIHNNYGSHVEIYRSLNAELTNRTN 446
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
          Length = 483

 Score =  299 bits (759), Expect = 9e-80
 Identities = 78/402 (19%), Positives = 142/402 (34%), Gaps = 32/402 (7%)

Query: 39  AWALGSERR-VLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGY----------- 86
           A    S +R    L L    A   LV   +   E    L+  H +++             
Sbjct: 2   AGKKSSGKRSWPLLGLLVTVATIHLVICPYTKVEESFNLQATHDLLYHQLDIDKYDHHEF 61

Query: 87  -GHLTWEWKRGLRSYLHPFIFAA----LYKILSLLHLDSPWFMAMAPRLLQSVFASFGDL 141
            G +        R++L P + AA    +  +LSLL +   +   +  R +  +    G  
Sbjct: 62  PGVVP-------RTFLGPLVIAAFSSPVVYVLSLLEVSKFY-SQLIVRGVLGLGVISGLW 113

Query: 142 YLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNS-VVSKQQAASKQSPPSRKMA 200
            L K  +  F   VA M   ++ T  +  F    ++     +     A +        + 
Sbjct: 114 TLQKEVRQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRRWALF 173

Query: 201 LLIAALACAI-RPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMY 259
           + ++A      R   A+      LL   Q +     +    +P G+  L +T  +D + +
Sbjct: 174 VWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSYFW 233

Query: 260 GSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLA 319
              +      L +N   +    +GT    WYF    P  +   L F   G +  R + LA
Sbjct: 234 RYLVWPEGVVLGYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYALA 293

Query: 320 GLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSV 379
              +  + +YS+L HKE RF++   P + + +      +     K        + L    
Sbjct: 294 LPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILN---KKSWPYKVRAMLVTGH 350

Query: 380 ILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVL 421
           IL+ +     +LY+S ++  G   AM  L       +   +L
Sbjct: 351 ILVNVAYTATSLYVSHFNYPGGV-AMQQLHELVP-PQTDVLL 390
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
           - fission yeast (Schizosaccharomyces pombe)
 emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
           [Schizosaccharomyces pombe]
          Length = 577

 Score =  298 bits (756), Expect = 2e-79
 Identities = 84/418 (20%), Positives = 162/418 (38%), Gaps = 38/418 (9%)

Query: 37  PWAWALGSERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK-- 94
           P      S     ++    R  +A   R   + DE +   E  H +++GYG  TWE+   
Sbjct: 6   PRKSLSVSFVWTFSILAVLRLTSASF-RVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPE 64

Query: 95  RGLRSYLHPFIFAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNH 154
             +RS+ +  + A    +   L L S   +    R + + F++F +  L       FN  
Sbjct: 65  YAIRSWFYIALHAVPGFLARGLGL-SRLHVFYFIRGVLACFSAFCETNLILAVARNFNRA 123

Query: 155 VA-HMETVLTV-TGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKM----ALLIAALAC 208
           VA H+ +VL V +G++    +         +     +++ SPPS K        I   A 
Sbjct: 124 VALHLTSVLFVNSGMWSASTSFLPSSFAMNMVTLALSAQLSPPSTKRTVKVVSFITIGAV 183

Query: 209 AIRPTSAITWLYVGLLDFIQMKSKSRFIF---LEVVPLGVFVLAVTTFLDCWMYGSRIIV 265
              P SA   +   LL+ + +K + R +F    + + + + +  +   +D   Y     V
Sbjct: 184 IGWPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQFV 243

Query: 266 PLNFLKFNLFSS---GGDYYGTHVFHWYFSQGFP---SMIWTFLPFSISGILKSR----- 314
             N +K+N+ +    G D YGT  + +YF+        ++W  +      +L +      
Sbjct: 244 AWNIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLVLLAAFTNWIN 303

Query: 315 -------EWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHN 367
                     ++   +W L ++ I  HKE RF+ P+ P + + +   L    +L  +  +
Sbjct: 304 LDSFLDLSSVISPFYIW-LFIFIIQPHKEERFMYPIYPVLCLAAAIGLDMSLKLMIQILS 362

Query: 368 EKGRLSRLKLSVILLIL------TNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKS 419
                 R K  V  ++L        + +A  +++ +          +S    D  V +
Sbjct: 363 SINETVRSKFPVRFVVLCVYAIIGCLSIARILAIQNYNAPMIIYPAISFLETDNNVTT 420
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
           could be the target of the GPI synthesis inhibitor,
           YW3548; Most likely an alpha 1,2 mannosyltransferase
           utilized for the addition of the third mannose onto the
           GPI core structure.; Gpi1>
 sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
 pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
 emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
          Length = 616

 Score =  294 bits (746), Expect = 3e-78
 Identities = 95/439 (21%), Positives = 176/439 (39%), Gaps = 80/439 (18%)

Query: 122 WFMAMAPRLLQSVFASFGDLYLYKLSKLIF------------------NNHVAHMETVLT 163
           + +  AP+++ +V AS G+ Y+ +  + ++                   + +     +L+
Sbjct: 135 YGVIYAPKIVMAVLASIGEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFALLLS 194

Query: 164 VTGLYYWFVAIESVKGNSVVSKQQAASKQSP---------PSRKMALLIAALACAIRPTS 214
           +T  +  F    +   +  +     A               S   +L+ A LAC  RP+S
Sbjct: 195 LTNFFNCFFITRTFINSFEMILTSIALYYWDWTGGQMIKESSFTKSLIFAFLACLQRPSS 254

Query: 215 AITWLYVGLLDFIQMKSKSRF-----IFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNF 269
            + W+   +   + +  K ++      F +V+     V      +D + Y         F
Sbjct: 255 GLIWVIPSISLILNLVGKKQYHLLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPFFRF 314

Query: 270 LKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKS------------REWR 317
           LKFN  +    +YG   +H++F Q  P ++   +P    G+                 ++
Sbjct: 315 LKFNFTTPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQ 374

Query: 318 LAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKL 377
           +   I+  L+VYS L HKEFRF+ P+ P   + S   L  + +   K      RLS LK 
Sbjct: 375 VKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLDRDYWK------RLSGLKS 428

Query: 378 SVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHY 437
            + L+   +V +AL +  +H+ G+ + M +L  E     + S+ F+MPCHSTP  S LH 
Sbjct: 429 LLWLVPFVSVFIALLLDTFHESGSIEVMKFLHEE---PEIDSLGFIMPCHSTPGQSYLHR 485

Query: 438 N--LPMRFLDCTPSEN-----------KGTLDESDRFLMNPADFVGEVFGN--------- 475
           +    +  + C P  +           +  +DESD    + + F+ + F           
Sbjct: 486 SDIQDLWSITCNPPLHLLGDPEAYSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSP 545

Query: 476 -----LSSFSHIVLFESEE 489
                    +++V+FE  E
Sbjct: 546 GKTYSHEWPTYLVVFEHME 564
 Score = 82.0 bits (201), Expect = 2e-14
 Identities = 38/74 (51%), Positives = 48/74 (64%)

Query: 45  ERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPF 104
             ++  + LAFR  NA+L RT+F  DE WQ LE AH   F YG LTWEWK G+RSYL P 
Sbjct: 14  RTQIFWVFLAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYGELTWEWKFGVRSYLFPM 73

Query: 105 IFAALYKILSLLHL 118
           IF   Y+++SL  +
Sbjct: 74  IFELTYRLVSLSSI 87
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
 gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
 emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
 gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
          Length = 488

 Score =  286 bits (726), Expect = 6e-76
 Identities = 84/402 (20%), Positives = 142/402 (34%), Gaps = 31/402 (7%)

Query: 39  AWALGSERRVLALALAFRAANALLVRTYFNPDE-------------HWQCLEVAHRIVFG 85
           A    S RR L L L    A   LV   +   E             HWQ LE    + F 
Sbjct: 2   AGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFP 61

Query: 86  YGHLTWEWKRGLRSYLHPFIFAA----LYKILSLLHLDSPWFMAMAPRLLQSVFASFGDL 141
            G +        R++L P + A        +LSLL +   +   +  R +  +   FG  
Sbjct: 62  -GVVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFY-SQLIVRGVLGLGVIFGLW 112

Query: 142 YLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKG-NSVVSKQQAASKQSPPSRKMA 200
            L K  +  F   VA M   +T    +  F    ++    ++     A +          
Sbjct: 113 TLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRHEWARF 172

Query: 201 LLIAALACAI-RPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMY 259
           + ++A A  + R    +    + LL     K          VP G+  L +T  +D + +
Sbjct: 173 IWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFW 232

Query: 260 GSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLA 319
                     L +N   +    +GT    WYF    P  +   L F   G++  R     
Sbjct: 233 RQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPT 292

Query: 320 GLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSV 379
            L +  + +YS+L HKE RF++   P + + +    + +     K        S L +  
Sbjct: 293 VLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNY-KKSWLYKAGSLLVIGH 351

Query: 380 ILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVL 421
           +++       ALY+S ++  G   AM  L +     +   +L
Sbjct: 352 LVVNAAYSATALYVSHFNYPGGV-AMQRLHQLVP-PQTDVLL 391
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
           mannosyltransferase [Homo sapiens]
          Length = 488

 Score =  285 bits (723), Expect = 1e-75
 Identities = 83/402 (20%), Positives = 141/402 (34%), Gaps = 31/402 (7%)

Query: 39  AWALGSERRVLALALAFRAANALLVRTYFNPDE-------------HWQCLEVAHRIVFG 85
           A    S RR L L L    A   LV   +   E             HWQ LE    + F 
Sbjct: 2   AGKGSSGRRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFP 61

Query: 86  YGHLTWEWKRGLRSYLHPFIFAA----LYKILSLLHLDSPWFMAMAPRLLQSVFASFGDL 141
            G +        R++L P + A        +LSLL +   +   +  R +  +   FG  
Sbjct: 62  -GVVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFY-SQLIVRGVLGLGVIFGLW 112

Query: 142 YLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKG-NSVVSKQQAASKQSPPSRKMA 200
            L K  +  F   VA M   +T    +       ++    ++     A +          
Sbjct: 113 TLQKEVRRHFGAMVATMFCWVTAMQFHLMVYCTRTLPNVLALPVVLLALAAWLRHEWARF 172

Query: 201 LLIAALACAI-RPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMY 259
           + ++A A  + R    +    + LL     K          VP G+  L +T  +D + +
Sbjct: 173 IWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFW 232

Query: 260 GSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLA 319
                     L +N   +    +GT    WYF    P  +   L F   G++  R     
Sbjct: 233 RQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVDRRTHAPT 292

Query: 320 GLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSV 379
            L +  + +YS+L HKE RF++   P + + +    + +     K        S L +  
Sbjct: 293 VLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCSYLLNNY-KKSWLYKAGSLLVIGH 351

Query: 380 ILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVL 421
           +++       ALY+S ++  G   AM  L +     +   +L
Sbjct: 352 LVVNAAYSATALYVSHFNYPGGV-AMQRLHQLVP-PQTDVLL 391
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
          Length = 919

 Score =  284 bits (720), Expect = 3e-75
 Identities = 73/429 (17%), Positives = 149/429 (34%), Gaps = 32/429 (7%)

Query: 3   HRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAW---ALGSERRVLALALAFRAAN 59
            R+RR      P      SS++  S +  ++P           G    +  +AL +    
Sbjct: 355 TRQRR------PLISDSSSSSSTKSYSKTDKPGRSNGGDAEDGGLRWFLPFIALCYLRYM 408

Query: 60  ALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAALYKILSLLH 117
           +       + DE +   E  H I++  G  TWE+     LRSYL+        +  S   
Sbjct: 409 SATSNIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFHELAGRPASWWF 468

Query: 118 LDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHM--ETVLTVTGLYYWFVAIE 175
            D    +  A RL   + ++  D  L       +   +A      +   +G ++   +  
Sbjct: 469 GDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLTSGCFFASTSFL 528

Query: 176 SVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRF 235
               +       +             +         P S + +L V +   ++   + + 
Sbjct: 529 PSSFSMYAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSLVK---RFKQ 585

Query: 236 IFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSG-GDYYGTHVFHWYFSQG 294
            F+      +F+L V+  +D + Y       LN L +N+   G    YGT    +Y   G
Sbjct: 586 AFIAGAVTTIFLLGVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNG 645

Query: 295 FPSMIWTFLPFSISGILKSREWR---------LAGLIVWVLVVYSILGHKEFRFVLPVLP 345
           F +  + F+   +   +     R         ++ + +W L   S+  HKE RF+ P+ P
Sbjct: 646 FNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW-LAFMSLQPHKEERFLYPIYP 704

Query: 346 FMFMFSGHNLAAMAQLKGKGHNEK-GRLSRLKLSVILLILTNVPMA----LYMSLYHQRG 400
            + + +   +  + +L  + ++ +   L  +   +  +IL  +  A     +  +     
Sbjct: 705 LICVSASAVIENIPELFREKYSSRESLLVTITKYMRPVILGCILCASHSRTFALINGYSA 764

Query: 401 TEDAMLYLS 409
             +    L 
Sbjct: 765 PLEVYKLLE 773
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
 gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
          Length = 678

 Score =  283 bits (718), Expect = 4e-75
 Identities = 81/394 (20%), Positives = 146/394 (36%), Gaps = 37/394 (9%)

Query: 53  LAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGY------------GHLTWEWKRGLRSY 100
           L F  A A LV T F   E    L+  H I++              G +        R++
Sbjct: 4   LIFVTAAAHLVYTPFTKVEESFNLQAMHDILYLRNNFTQYDHHDYPGVVP-------RTF 56

Query: 101 LHPF---IFAALYKIL-SLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVA 156
           + P    I +A + +L   L ++  W      RL+ +   S     L +    I+   V 
Sbjct: 57  IGPLVVSIISAPFVLLFETLSINKFWA-QYVVRLVLAGAISVAWNSLRQAVTKIYGVEVR 115

Query: 157 HMETVLTVTGLYYWFVAIESVKG--NSVVSKQQAASKQSPPSRKMALLIAALACAI-RPT 213
              T +T+T  ++ F     +       +     A        K  ++ + ++  + R  
Sbjct: 116 LWFTAITITQFHFMFYMTRPLPNIFALPIVLFAIAYWLRDQ-HKPFIICSGISILVFRSE 174

Query: 214 SAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFN 273
            A+    + ++  ++ K     +    +P GV +LA T  +D + +   +      L +N
Sbjct: 175 LALFLGILLVVSLLRRKVSIDGLLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYN 234

Query: 274 LFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGI-LKSREWRLAGLIVWVLVVYSIL 332
              +    +GT  F WYF    P  +   L     G+ L+ R   L    +  +++YSIL
Sbjct: 235 TVLNKSSNWGTSPFLWYFYSALPRAMGASLVLVPIGVALEPRIRPLVLSALLFVLLYSIL 294

Query: 333 GHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALY 392
            HKE RF++ V P + + +      +         +    S L L+    +L NV + L+
Sbjct: 295 PHKELRFIIYVFPVLNIAAACACQRI----WMNSAKSTWHSFLALACGAHLLLNVFITLF 350

Query: 393 M---SLYHQRGTEDAMLYLSREAHDGRVKSVLFL 423
           +   S  +  G   A+  L R        SV   
Sbjct: 351 LLVISGTNYPGG-AALSRLHRLEAGTSNVSVHIS 383
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
          Length = 570

 Score =  269 bits (683), Expect = 6e-71
 Identities = 73/429 (17%), Positives = 149/429 (34%), Gaps = 32/429 (7%)

Query: 3   HRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAW---ALGSERRVLALALAFRAAN 59
            R+RR      P      SS++  S +  ++P           G    +  +AL +    
Sbjct: 6   TRQRR------PLISDSSSSSSTKSYSKTDKPGRSNGGDAEDGGLRWFLPFIALCYLRYM 59

Query: 60  ALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAALYKILSLLH 117
           +       + DE +   E  H I++  G  TWE+     LRSYL+        +  S   
Sbjct: 60  SATSNIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFHELAGRPASWWF 119

Query: 118 LDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHM--ETVLTVTGLYYWFVAIE 175
            D    +  A RL   + ++  D  L       +   +A      +   +G ++   +  
Sbjct: 120 GDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLTSGCFFASTSFL 179

Query: 176 SVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRF 235
               +       +             +         P S + +L V +   ++   + + 
Sbjct: 180 PSSFSMYAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSLVK---RFKQ 236

Query: 236 IFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSG-GDYYGTHVFHWYFSQG 294
            F+      +F+L V+  +D + Y       LN L +N+   G    YGT    +Y   G
Sbjct: 237 AFIAGAVTTIFLLGVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNG 296

Query: 295 FPSMIWTFLPFSISGILKSREWR---------LAGLIVWVLVVYSILGHKEFRFVLPVLP 345
           F +  + F+   +   +     R         ++ + +W L   S+  HKE RF+ P+ P
Sbjct: 297 FNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW-LAFMSLQPHKEERFLYPIYP 355

Query: 346 FMFMFSGHNLAAMAQLKGKGHNEK-GRLSRLKLSVILLILTNVPMA----LYMSLYHQRG 400
            + + +   +  + +L  + ++ +   L  +   +  +IL  +  A     +  +     
Sbjct: 356 LICVSASAVIENIPELFREKYSSRESLLVTITKYMRPVILGCILCASHSRTFALINGYSA 415

Query: 401 TEDAMLYLS 409
             +    L 
Sbjct: 416 PLEVYKLLE 424
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
           architecture [Schizosaccharomyces pombe]
          Length = 547

 Score =  246 bits (624), Expect = 5e-64
 Identities = 64/401 (15%), Positives = 131/401 (31%), Gaps = 34/401 (8%)

Query: 47  RVLALALAFRAANALLVRTYFNPDEH--------------WQCLEVAHRIVFGYGHLTWE 92
             LA  L          +T F   E               W   +V   + F        
Sbjct: 9   WYLANILLVTCIGYYSYKTPFTKVEESFAMQAIHDIQTYRWDLSKVYDHLEFPGAVK--- 65

Query: 93  WKRGLRSYLHPFIFAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFN 152
                RS++     A L  I S           +A R      +      +       F 
Sbjct: 66  -----RSFIPSLFIAVLSYIPSW-----FVNPLLAARWTIGYLSWESMNSVSCSISKRFG 115

Query: 153 NHVAHMETVLTVTGLYYWFVAIESVKG-NSVVSKQQAASKQSPPSRKMALLIAAL-ACAI 210
                +  + +    +  +     +     +++   + S     +   ++ I    A  +
Sbjct: 116 TLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKNNYYGSISILVFAAAIV 175

Query: 211 RPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFL 270
           R   A+  + + L   +Q +     + L  +   +  +  +  +D + +G+     L   
Sbjct: 176 RSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWPELEAF 235

Query: 271 KFNLFSSGGDYYGTHVFHWYFSQG-FPSMIWTFLPFSISGILKSREWRLAGL-IVWVLVV 328
            FN+       +GT  F++YF +  +  +  T L F +   +  +  RL     ++ + V
Sbjct: 236 LFNVVEGKSSDWGTSPFYYYFVRLPWLFLNPTTLLFLLISFVYIKPARLLIYVPLFFIFV 295

Query: 329 YSILGHKEFRFVLPVLPFMFMFSGHNLA-AMAQLKGKGHNEKGRLSRLKLSVILLILTNV 387
           YS LGHKE+RF++  +P+    S    +      K      +         +I   + + 
Sbjct: 296 YSFLGHKEWRFIIYSIPWFNAASAIGASLCFNASKFGKKIFEILRLMFFSGIIFGFIGSS 355

Query: 388 PMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPCHS 428
            + LY+  Y   G   A+  L    +  +V   + + PC +
Sbjct: 356 FL-LYVFQYAYPGGL-ALTRLYEIENHPQVSVHMDVYPCMT 394
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
           lipid-linked oligosaccharides; Alg9p [Saccharomyces
           cerevisiae]
 sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
 pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
 emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
          Length = 555

 Score =  238 bits (604), Expect = 1e-61
 Identities = 68/384 (17%), Positives = 132/384 (33%), Gaps = 23/384 (5%)

Query: 46  RRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHP 103
             +L L    R           + DE +   E  + +V G+G  TWE+     +RS+   
Sbjct: 8   ISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYSIRSWAFL 67

Query: 104 FIF-AALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVL 162
             F   LY +     L+S W      R     F+   +  L++         +A++  + 
Sbjct: 68  LPFYCILYPVNKFTDLESHWN-FFITRACLGFFSFIMEFKLHREIAGSLALQIANIWIIF 126

Query: 163 TVT--GLYYWFVAIESVKGNSVV------SKQQAASKQSPPSRKMALLIAALA-CAIRPT 213
            +   G ++  V +       ++         +  S  S  +   +L    LA     P 
Sbjct: 127 QLFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGSTSNFTKSLAYNFLASILGWPF 186

Query: 214 SAITWLYVGLLDFIQMK-SKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKF 272
             I  L + L      +   +     +   +           D   YG    V  N L +
Sbjct: 187 VLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAPVSWNILFY 246

Query: 273 NLFS----SGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAGLIVWVLVV 328
           N+ +    SG + +G   +++Y      +     L  +I GI   R W L   +   + V
Sbjct: 247 NVINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHLRLWPLWASLFTWIAV 306

Query: 329 YSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVP 388
           ++   HKE RF+ P+   + + +        ++    + +      +KLSV+L++     
Sbjct: 307 FTQQPHKEERFLYPIYGLITLSASIAF---YKVLNLFNRKPILKKGIKLSVLLIVAGQA- 362

Query: 389 MALYMSLY-HQRGTEDAMLYLSRE 411
           M+  ++L  +           S  
Sbjct: 363 MSRIVALVNNYTAPIAVYEQFSSL 386
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
 sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
 pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
          Length = 551

 Score =  232 bits (588), Expect = 9e-60
 Identities = 57/438 (13%), Positives = 138/438 (31%), Gaps = 71/438 (16%)

Query: 46  RRVLALALAFRAANALLVRTYFNPDEHWQCLE--------------VAHRIVFGYGHLTW 91
           R  +   +     +  L++  F   E    ++                  + F  G +  
Sbjct: 2   RWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFP-GVVP- 59

Query: 92  EWKRGLRSYLHPFIFAALYKILSLLHL------DSPWFMAMAPRLLQSVFASFGDLYLYK 145
                 R+++   I A L +    L         +   + +  R +  +      +YL  
Sbjct: 60  ------RTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKN 113

Query: 146 LSKLIFNNHV------------------AHMETVLTVTGLYYWFVAIESVKGNSVV--SK 185
             + +F+                          +  +   +  F +  ++    +     
Sbjct: 114 CLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLT 173

Query: 186 QQAASKQSPPSRKMALLIAAL-ACAIRPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLG 244
             A           A+ ++AL A   R   +     + L   I      +    + +  G
Sbjct: 174 NVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVI----FKKISLFDAIKFG 229

Query: 245 VFVLAV----TTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIW 300
           +F L +    +  +D + +    +  ++   FN+ +     +G      YF+     M  
Sbjct: 230 IFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPVTAYFTHYLRMM-- 287

Query: 301 TFLPFSISGI------LKSREWRL-AGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGH 353
            F+P ++  +      L   + ++ +   ++ ++V S   HKE+RF++  +P + +    
Sbjct: 288 -FMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGAT 346

Query: 354 NLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMA-LYMSLYHQRGTEDAMLYLSREA 412
             A + +              + L + ++    + MA LY+S  +  G E    +     
Sbjct: 347 GAAHLWENMKVKKITNVLCLAI-LPLSIMTSFFISMAFLYISRMNYPGGEALTSFNDMIV 405

Query: 413 HDG-RVKSVLFLM-PCHS 428
                  +V   + PC +
Sbjct: 406 EKNITNATVHISIPPCMT 423
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
 gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
          Length = 492

 Score =  231 bits (584), Expect = 3e-59
 Identities = 73/380 (19%), Positives = 128/380 (33%), Gaps = 39/380 (10%)

Query: 57  AANALLVRTYFNPDEHWQCLEVAHRIVFGY-------------GHLTWEWKRGLRSYLHP 103
                ++       E    ++  H ++F               G +        R+++ P
Sbjct: 11  VTIIHIILAPGTKVEESFNVQATHDLMFHLPTNLSNYDHSQFPGVVP-------RTFIGP 63

Query: 104 FIFAALYK----ILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHME 159
              A L      I     +   W + +  R    +  +   LY  +     F    A   
Sbjct: 64  ISLAILSSPMSFIFRFWAIPKMWQLLLI-RATLGLMNAMAFLYFARSVNRKFGRETAMYL 122

Query: 160 TVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWL 219
            ++  T  +Y F     +     +       ++    R  + +  A A  I     +  L
Sbjct: 123 RLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYESAVRYATASVILFRCELVLL 182

Query: 220 YVGLLDFIQMKSKSRFI-----FLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNL 274
           Y  +     +  + +           V +    LAV+  +D + +G  +      + FN+
Sbjct: 183 YGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFWGRPLWPEGEVMFFNV 242

Query: 275 FSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREW-RLAGLIVWVLVVYSILG 333
             +    YGT  F WYF    P  + T       G+L  R   ++    V  + +YS L 
Sbjct: 243 VENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQIVLPSVIFIFLYSFLP 302

Query: 334 HKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVP---MA 390
           HKE RF++ VLP   + +    A M   + K          L   VIL +L NV    M 
Sbjct: 303 HKELRFIIYVLPIFCLSAAVFCARMLINRHKSFFRMI----LFFGVILHLLANVLCTGMF 358

Query: 391 LYMSLYHQRGTEDAMLYLSR 410
           L ++  +  G  DA+ YL  
Sbjct: 359 LLVASKNYPG-FDALNYLQF 377
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
          Length = 369

 Score =  224 bits (567), Expect = 2e-57
 Identities = 71/345 (20%), Positives = 120/345 (34%), Gaps = 27/345 (7%)

Query: 79  AHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYK----ILSLLHLDSPWFMAMAPRLLQSV 134
                F  G +        R+++ P   A L      I     +   W + +  R    +
Sbjct: 5   YDHSQFP-GVVP-------RTFIGPISLAILSSPMSFIFRFWAIPKMWQLLLI-RATLGL 55

Query: 135 FASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQSP 194
             +   LY  +     F    A    ++  T  +Y F     +     +       ++  
Sbjct: 56  MNAMAFLYFARSVNRKFGRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLL 115

Query: 195 PSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFI-----FLEVVPLGVFVLA 249
             R  + +  A A  I     +  LY  +     +  + +           V +    LA
Sbjct: 116 EGRYESAVRYATASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLA 175

Query: 250 VTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISG 309
           V+  +D + +G  +      + FN+  +    YGT  F WYF    P  + T       G
Sbjct: 176 VSIPIDSYFWGRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLG 235

Query: 310 ILKSREW-RLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNE 368
           +L  R   ++    V  + +YS L HKE RF++ VLP   + +    A M   + K    
Sbjct: 236 LLVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFFR 295

Query: 369 KGRLSRLKLSVILLILTNVP---MALYMSLYHQRGTEDAMLYLSR 410
                 L   VIL +L NV    M L ++  +  G  DA+ YL  
Sbjct: 296 MI----LFFGVILHLLANVLCTGMFLLVASKNYPG-FDALNYLQF 335
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
          Length = 509

 Score =  219 bits (554), Expect = 8e-56
 Identities = 72/319 (22%), Positives = 136/319 (42%), Gaps = 24/319 (7%)

Query: 48  VLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFA 107
           +  LAL  R   A+    Y++PDE +Q LE AHR+ FGY  + WE++ G+R  L P + A
Sbjct: 26  ITLLALCLR-MTAIFPIGYYHPDEIFQYLEQAHRLAFGYSVIPWEYRYGMRGGLVPVLLA 84

Query: 108 ALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLI--FNNHVAHMETVLTVT 165
           A  K+  +++  S  +  + P  + ++ +       YKL +L   F   +A     + V 
Sbjct: 85  AAMKMGDIMNTQSFLYWVL-PHAITALLSLGVIWSAYKLGRLHSFFTGCLA-----MFVA 138

Query: 166 GLYY---WFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIA-----ALACAIRPTSAIT 217
             +Y    F A    +  S  +   AA       +K + LI       L+  +R     +
Sbjct: 139 ATWYEIVLFAAHPLSESLSFAAFMPAAYYLIAEEKKKSSLILSGFLMGLSALLRFQYIPS 198

Query: 218 WLYVGLLDF-IQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFS 276
            L++ L    I ++    FI       G+  + +++  D ++    ++     ++ NL  
Sbjct: 199 ILFITLFTLRINVRQWGYFIL-----GGLGAVFISSLSDIFIGEYPLLWLFKNIQQNLIF 253

Query: 277 SGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREW-RLAGLIVWVLVVYSILGHK 335
              + YGT   + YF   + +  W  L   I  ++ +  +  L G  +  L+ + ++ HK
Sbjct: 254 HRAEDYGTAPIYSYFFDIWTNWKWFSLILPIPILVAAYRYPALFGTALVNLIFHMLVSHK 313

Query: 336 EFRFVLPVLPFMFMFSGHN 354
           E+RF+        + +   
Sbjct: 314 EYRFIFLSSGIFIILAAIG 332
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
           most likely an alpha 1,2 mannosyltransferase utilized
           for addition of the fourth, side-branching mannose onto
           the GPI core structure.; Smp3p [Saccharomyces
           cerevisiae]
 sp|Q04174|SMP3_YEAST SMP3 PROTEIN
 pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
 gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
 emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
          Length = 516

 Score =  218 bits (552), Expect = 2e-55
 Identities = 86/423 (20%), Positives = 148/423 (34%), Gaps = 42/423 (9%)

Query: 46  RRVLALALAFRAANALLVRTYFNPDEHWQCLEV-AHRIVFGYGHLTWEW--KRGLRSYLH 102
           +  L L  A      L    Y +PDEH+QC+E+ A + +   G + WE+  K   RSY  
Sbjct: 5   QWWLYLVYAIGLMLCLGPS-YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSY-G 62

Query: 103 PFIFAA--LYKILSLLH--LDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHM 158
           P +     L+ IL       D+P  +  + RL   V       +L           V  M
Sbjct: 63  PLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFM 122

Query: 159 ETVLTVTGLYYWFVAIESVKGNSVVSKQQAAS---------KQSPPSRKMALLIAALACA 209
           +  L +T    W     +   +       +           K    S     +I  L  +
Sbjct: 123 QKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFS 182

Query: 210 IRPTSAITWLYVGLLDFIQMKSKSRFIFLE----VVPLGVFVLAVTTFLDCWMYGS---R 262
               + +T+     L  + +  K   +  +    ++    F   +   +D  +Y +    
Sbjct: 183 FGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGF 242

Query: 263 IIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAGLI 322
           +I PLN LK+NL       +G H  + +     P ++   L  +I    K  +      I
Sbjct: 243 VITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYA-I 301

Query: 323 VWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILL 382
           +  L+  S   H+E RF++P++P +      N   ++         KG            
Sbjct: 302 ISGLLFLSFFQHQELRFLVPLVPLLVT--NLNWTPLSSTLVNKKIFKGTW---------- 349

Query: 383 ILTNVPMALYMSLYHQRGTEDAM-LYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLPM 441
           +L N+ MA  M + HQ G    +  Y            V      +S P +  +  NL +
Sbjct: 350 LLFNIIMAFIMGISHQAGIIQFLGDYFHF---RTEQMGVHIWWKTYSPPTWMYMSNNLTV 406

Query: 442 RFL 444
             L
Sbjct: 407 SSL 409
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
          Length = 516

 Score =  215 bits (544), Expect = 1e-54
 Identities = 84/423 (19%), Positives = 147/423 (33%), Gaps = 42/423 (9%)

Query: 46  RRVLALALAFRAANALLVRTYFNPDEHWQCLEV-AHRIVFGYGHLTWEW--KRGLRSYLH 102
           +  L L  A      L    Y +PDEH+QC+E+ A + +   G + WE+  K   RSY  
Sbjct: 5   QWWLYLVYAIGLMLCLGPS-YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSY-G 62

Query: 103 PFIFAA--LYKILSLLH--LDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHM 158
           P +     L+ IL       D+P  +  + RL   V       +L           V  +
Sbjct: 63  PLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFI 122

Query: 159 ETVLTVTGLYYWFVAIESVKGNSVVSKQQAAS---------KQSPPSRKMALLIAALACA 209
           +  L +T    W     +   +       +           K          +I  L  +
Sbjct: 123 KKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNGKNIQRRNFKNSVILGLIFS 182

Query: 210 IRPTSAITWLYVGLLDFIQMKSKSRFIFLE----VVPLGVFVLAVTTFLDCWMYGS---R 262
               + +T+     L  + +  K   +  +    ++    F   +   +D  +Y +    
Sbjct: 183 FGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGF 242

Query: 263 IIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAGLI 322
           +I PLN LK+NL       +G H  + +     P ++   L  +I    K  +      I
Sbjct: 243 VITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQILGPVLLLAIFSGYKLDKLSTYA-I 301

Query: 323 VWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILL 382
           +  L+  S   H+E RF++P++P +      N   ++         KG            
Sbjct: 302 ISGLLFLSFFQHQELRFLVPLVPLLVT--NLNWTPLSSTLVNKKIFKGTW---------- 349

Query: 383 ILTNVPMALYMSLYHQRGTEDAM-LYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLPM 441
           +L N+ MA  M + HQ G    +  Y            V      +S P +  +  NL +
Sbjct: 350 LLFNIIMAFIMGISHQAGIIQFLGDYFHF---RTEQMGVHIWWKTYSPPTWMYMSNNLTV 406

Query: 442 RFL 444
             L
Sbjct: 407 SSL 409
>ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
 pir||S75173 hypothetical protein sll1946 - Synechocystis sp. (strain PCC 6803)
 dbj|BAA17087.1| (D90903) ORF_ID:sll1946~unknown protein [Synechocystis sp. PCC
           6803]
          Length = 825

 Score =  212 bits (535), Expect = 1e-53
 Identities = 57/400 (14%), Positives = 122/400 (30%), Gaps = 64/400 (16%)

Query: 40  WALGSERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLT--------- 90
             L     V  L       +  L R +   D+     + ++ + +G  +L          
Sbjct: 4   QILSKSWGVPLLLAMVWLGSNGLDRLWLGMDQTVPAWDQSNHLSYGLEYLQALRSPEFLS 63

Query: 91  --WEWKRGLRSYLHP---FIFAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYK 145
             W     + S  +P   +I  A ++ L     D              +++    L +Y 
Sbjct: 64  GEWWRSFWMLSPKYPPLTYIVNAPFQGLGGPGSDLALLSNW-------LWSGILILSVYG 116

Query: 146 LSKLIFNNH-----VAHMETVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMA 200
           L K +F+       VA M  +  +       +    +   +++S       +    R  +
Sbjct: 117 LGKKLFSREIGLWAVAIMVLIPRLIHSRLIVLLDSPLLAFTLLSFTCLTYWKEAEGR-RS 175

Query: 201 LLIAALACAIRPTSAI----TWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDC 256
             + A+A  +     +    + ++      + +   S +         + V  +   +  
Sbjct: 176 QWLWAIAAGVGLGLGLLSKQSIIFYLFFPLVGLGLWSIWTKQWQRLAQLLV-GLLASIPL 234

Query: 257 WMYGSRIIVPLNF-LKFNLFSSGGDYYGTHVF-----HWYFSQGFPSMI-WTFLPFSISG 309
           W    R      F    N  +      G           Y+ Q  P+ + W +L   + G
Sbjct: 235 WYPWYRTNWIYLFSTAQNSNAIPATLEGDPPVNTLAAWTYYWQDLPNALSWVWLIPPLVG 294

Query: 310 IL------------KSREWRLAGLIVW-------VLVVYSILGHKEFRFVLPVLPFMFMF 350
           ++                      ++W         ++ S + +K+ R++LP LP + +F
Sbjct: 295 VILSLLNRFPASLQIPSWREAKPGLLWLGYYYGGTYLICSAIQNKDDRYILPYLPIVAIF 354

Query: 351 SGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMA 390
               L         G     R   L ++ IL+ L N+   
Sbjct: 355 LAFGLTR-----WCGRWLWVRWGTLAIT-ILITLGNLFPI 388
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
 dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
          Length = 579

 Score =  210 bits (531), Expect = 4e-53
 Identities = 88/455 (19%), Positives = 143/455 (31%), Gaps = 99/455 (21%)

Query: 54  AFRAANALLVRT-YFNPDEHWQCLEVAHRIVFG-YGHLTWEW--KRGLRSYLHPFIF-AA 108
             R    LL +T Y +PDE +Q  EV    + G      WE+      RS L P +   +
Sbjct: 43  LLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGS 102

Query: 109 LYKILSLL-------HLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETV 161
            + +L L         L S + + + PRLL +  +   D  +Y L+  +          +
Sbjct: 103 TFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPM---GADRWNAL 159

Query: 162 LTVTGL-----YYWFVAIESVKGNSVVSKQQAASKQS------------PPSRKMAL-LI 203
             ++G      +Y      +++G          S               P  R   L  I
Sbjct: 160 ALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWLLGGI 219

Query: 204 AALACAIRPTSAITWLYVGLLD---------FIQMKSKSRFIFLEVVPLGVFVLAVTTFL 254
            A     RPT     +    L             +  ++    L ++P      AV    
Sbjct: 220 VAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREA----LVLLPGATLTAAVFVAT 275

Query: 255 DCWMY------GSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYF-SQGFPSM--------- 298
           D W +       + ++ P+NFL +NL       +GTH    +    GF            
Sbjct: 276 DSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQ 335

Query: 299 ---------------IWTFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEFRFVLPV 343
                          +          +L S    L  L    L + S   H+E RF++P+
Sbjct: 336 AAWQQLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPL 395

Query: 344 LPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTED 403
           L  + +           +  KG                ++L N   AL     HQ G   
Sbjct: 396 LVPLVLLCS---PQTQPVPWKGT---------------VVLFNALGALLFGCLHQGGLVP 437

Query: 404 AMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYN 438
            + YL +  H      VL   P H T  ++  +  
Sbjct: 438 GLEYLEQVVHAP----VLPSTPTHYTLLFTHTYMP 468
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
 pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
          Length = 533

 Score =  210 bits (531), Expect = 4e-53
 Identities = 71/402 (17%), Positives = 138/402 (33%), Gaps = 60/402 (14%)

Query: 48  VLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGH-LTWEW--KRGLRSY---- 100
           +    L  R   +    +Y +PDEH Q  ++    +FG+   L WE+  K+ +RS     
Sbjct: 10  IYTFLLILRFWFSQ-GSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSVVPLN 68

Query: 101 LHPFIFAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMET 160
           +       L + +   +  SP+ + +  RL   + +   DL ++ +  L      A    
Sbjct: 69  VMLLPIFLLCRCICKSNC-SPYPILLFTRLYMCLISLLIDLSIWNIVPLN-----ARWSA 122

Query: 161 VLTVTGLYYW-------FVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRP- 212
           +L  +  +         F          +     +     P ++K++ L   L   +   
Sbjct: 123 LLLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIVSVL 182

Query: 213 ----------TSAITWLYVGLLDFIQMKSKSRFIFLE---VVPLGVFVLAVTTFLDCWMY 259
                          ++Y  +  F +  +  + IFL     V +    +      D   Y
Sbjct: 183 GFFTRITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDYKFY 242

Query: 260 GSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLA 319
           G  +I   N LK+N        +G H    +F    P +    +      + K  + R  
Sbjct: 243 GVFVITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGPLI-----FVPKLWDVRKP 297

Query: 320 GLIVWVL--VVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKL 377
              +W+L   + S+  H+E RF+LP      + SG     + +                 
Sbjct: 298 ATWLWLLPVFILSLFPHQEPRFLLPAASIFIVNSG----CLVRSYWIK------------ 341

Query: 378 SVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKS 419
              L ++  V +A++  + HQ G   A+L +        V +
Sbjct: 342 --FLFVMYAVVLAVFFGIMHQNGVIPAVLEVKNIIEQRNVTT 381
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
          Length = 278

 Score =  181 bits (456), Expect = 3e-44
 Identities = 58/235 (24%), Positives = 99/235 (41%), Gaps = 48/235 (20%)

Query: 294 GFPSMIWTFLPFSISGILKS------------REWRLAGLIVWVLVVYSILGHKEFRFVL 341
             P ++   +P    G+                 +++   I+  L+VYS L HKEFRF+ 
Sbjct: 1   ALPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIF 60

Query: 342 PVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGT 401
           P+ P   + S   L  + +   K      RLS LK  + L+   +V +AL +  +H+ G+
Sbjct: 61  PLQPLFILISSFGLLRLDRDYWK------RLSGLKSLLWLVPFVSVFIALLLDTFHESGS 114

Query: 402 EDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYN--LPMRFLDCTPSEN-------- 451
            + M +L  E     + S+ F+MPCHSTP  S LH +    +  + C P  +        
Sbjct: 115 IEVMKFLHEE---PEIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCNPPLHLLGDPEAY 171

Query: 452 ---KGTLDESDRFLMNPADFVGEVFGN--------------LSSFSHIVLFESEE 489
              +  +DESD    + + F+ + F                    +++V+FE  E
Sbjct: 172 SKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLVVFEHME 226
>ref|NP_488731.1| (NC_003272) unknown protein [Nostoc sp. PCC 7120]
 dbj|BAB76390.1| (AP003597) ORF_ID:alr4691~unknown protein [Nostoc sp. PCC 7120]
          Length = 541

 Score =  171 bits (431), Expect = 2e-41
 Identities = 41/311 (13%), Positives = 96/311 (30%), Gaps = 32/311 (10%)

Query: 104 FIFAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLT 163
           ++ A+ Y++  +           + RL   +F       +Y++ K++    +A +   + 
Sbjct: 80  WLIASFYQLFGVNE--------FSVRLPSMIFGVLCLFLVYEIGKIMLGKTLAWLSAAIL 131

Query: 164 VTGLYYWFVAIESVKGNSVVSKQQAASKQS------PPSRKMALLIAALA----CAIRPT 213
                +   +        ++     A          P  R     I  L+      +R  
Sbjct: 132 SVEFLWLQYSRLGNPDLPMIFLVLLAIYLLIQAELHPQYRDYFSFIVGLSLGLGFLMRSF 191

Query: 214 SAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSR----IIVPLNF 269
                    L   I    + R +    + LGV +  +   +  W    R        L  
Sbjct: 192 VIFLPTVALLPYLITEHRRHRHLTNPWLYLGVVIGFIPILIWSWFNWQRDGNNTFTHLVN 251

Query: 270 LKFNLFSSGGDYYGTHVFHWYFSQGFP-SMIWTFLPFSISGILKSREWR-----LAGLIV 323
               +F  G +    +   +YF      +  W         ++  R W      L G  +
Sbjct: 252 F---VFLLGSEERDGNGILFYFWNTLLKAFPWPCFSLLGLLLIIRRPWHRYNLILIGFPI 308

Query: 324 WVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEK-GRLSRLKLSVILL 382
            +L   +I   +   + L + PF+ + +   L  + ++    + ++     +  +  IL 
Sbjct: 309 VLLAELTIFSTRLSHYALSLYPFIALLAAVGLDWLGKVYEMEYTKRKSLWRKGNIPQILS 368

Query: 383 ILTNVPMALYM 393
             +     L++
Sbjct: 369 YTSGALGILFL 379
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
          Length = 198

 Score =  162 bits (407), Expect = 2e-38
 Identities = 41/192 (21%), Positives = 64/192 (32%), Gaps = 20/192 (10%)

Query: 5   RRRNAA---GPPPPEGIG-----GSSTAEASSTGEERPDLPWAWALGSERRVLALALAFR 56
           R + +    G   P         GS  A  +    E            E       L   
Sbjct: 9   RLKGSGGSSGDTAPAADKLRELLGSREAGGAEHRTELSGNKAGQVWAPEGSTAFKCLLSA 68

Query: 57  AANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWK--RGLRSYLHPFIFAAL----Y 110
              A L+    + DE +   E  H +++G G  TWE+     +RSY +  + A       
Sbjct: 69  RLCAALLSNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHA 128

Query: 111 KILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTV--TGLY 168
           +IL    +   +F+    R L +  +   +LY YK     F  HV+ M     V  TG++
Sbjct: 129 RILQTNKILVFYFL----RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTGMF 184

Query: 169 YWFVAIESVKGN 180
                  S    
Sbjct: 185 CSSSVYPSPLIC 196
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
          Length = 457

 Score =  147 bits (370), Expect = 3e-34
 Identities = 59/340 (17%), Positives = 96/340 (27%), Gaps = 84/340 (24%)

Query: 157 HMETVLTVTGL-----YYWFVAIESVKGNSVVSKQQAASKQS------------PPSRKM 199
               +  ++G      +Y      +++G          S               P  R  
Sbjct: 33  RWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSW 92

Query: 200 AL-LIAALACAIRPTSAITWLYVGLLD---------FIQMKSKSRFIFLEVVPLGVFVLA 249
            L  I A     RPT     +    L             +  ++    L ++P      A
Sbjct: 93  LLGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREA----LVLLPGATLTAA 148

Query: 250 VTTFLDCWMY------GSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYF-SQGFPSM---- 298
           V    D W +       + ++ P+NFL +NL       +GTH    +    GF       
Sbjct: 149 VFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLH 208

Query: 299 --------------------IWTFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEFR 338
                               +          +L S    L  L    L + S   H+E R
Sbjct: 209 AQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEAR 268

Query: 339 FVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQ 398
           F++P+L  + +           +  KG                + L N   AL     HQ
Sbjct: 269 FLIPLLVPLVLLCS---PQTQPVPWKGT---------------VALFNALGALLFGCLHQ 310

Query: 399 RGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYN 438
            G    + YL +  H      VL   P H T  ++  +  
Sbjct: 311 GGLVPGLEYLEQVVHAP----VLPSTPTHYTLLFTHTYMP 346
>gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protein MGC3136 [Mus musculus]
          Length = 385

 Score =  146 bits (367), Expect = 7e-34
 Identities = 41/230 (17%), Positives = 75/230 (31%), Gaps = 27/230 (11%)

Query: 39  AWALGSERR-VLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGY----------- 86
           A    S +R    L L    A   LV   +   E    L+  H +++             
Sbjct: 2   AGKKSSGKRSWPLLGLLVTVATIHLVICPYTKVEESFNLQATHDLLYHQLDIDKYDHHEF 61

Query: 87  -GHLTWEWKRGLRSYLHPFIFAA----LYKILSLLHLDSPWFMAMAPRLLQSVFASFGDL 141
            G +        R++L P + AA    +  +LSLL +   +   +  R +  +    G  
Sbjct: 62  PGVVP-------RTFLGPLVIAAFSSPVVYVLSLLEVSKFY-SQLIVRGVLGLGVISGLW 113

Query: 142 YLYKLSKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNS-VVSKQQAASKQSPPSRKMA 200
            L K  +  F   VA M   ++ T  +  F    ++     +     A +        + 
Sbjct: 114 TLQKEVRQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAWLQRRWALF 173

Query: 201 LLIAALACAI-RPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLA 249
           + ++A      R   A+      LL   Q +     +    +P G+  L 
Sbjct: 174 VWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLG 223
 Score = 39.9 bits (93), Expect = 0.096
 Identities = 28/198 (14%), Positives = 56/198 (28%), Gaps = 32/198 (16%)

Query: 235 FIFLEVVPLGVFVLAVTTFLDCW-------MYGSRIIVPLNFLKFNLFSSGGDYYGTHVF 287
           +   + V           F            Y +R +   N L   +             
Sbjct: 113 WTLQKEVRQQFGATVAVMFCWISATQFHLMFYCTRTLP--NVLALAVVLPALT------- 163

Query: 288 HWYFSQGFPSMIWTFLPFSISGILKSREWRLAGLIVWVLVVYSILGH----KEFRFVLPV 343
                  +    W    +  + ++      LA L+   L++          +  R  +P 
Sbjct: 164 ------AWLQRRWALFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPA 217

Query: 344 LPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGTED 403
              + +     LA++  L  K        + L    IL+ +     +LY+S ++  G   
Sbjct: 218 -GLLCL---GKLASLVCLLNKKSWPYKVRAMLVTGHILVNVAYTATSLYVSHFNYPGGV- 272

Query: 404 AMLYLSREAHDGRVKSVL 421
           AM  L       +   +L
Sbjct: 273 AMQQLHELVP-PQTDVLL 289
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
          Length = 830

 Score =  131 bits (328), Expect = 3e-29
 Identities = 45/273 (16%), Positives = 82/273 (29%), Gaps = 51/273 (18%)

Query: 203 IAALACAIRPTSAITWLYVGLLDFIQ-------MKSKSRFIFLEVVPLGVFVLAVTTFLD 255
           I       RPT  +    +     ++                       +  L +  F D
Sbjct: 231 ICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFIFCD 290

Query: 256 CWMYGS---------------RIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSM-- 298
              Y                  +  P NF+K NL S+    +G H  + +     P +  
Sbjct: 291 SLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPMLFN 350

Query: 299 IWTFLPFSISGILKSREWR---------------LAGLIVWVLVVYSILGHKEFRFVLPV 343
           +           L  R +R               ++G I   L   S++ H+E RF+LPV
Sbjct: 351 VLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFLLPV 410

Query: 344 -LPFMFMFSGHNLAAMA-QLKGKGHNEKGRLSRLKL---------SVILLILTNVPMALY 392
             P + + +   +   + +   +  +   RL   KL          + +  ++NV + L+
Sbjct: 411 TFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVALTLF 470

Query: 393 MSLYHQRGTEDAMLYL-SREAHDGRVKSVLFLM 424
               HQ G       +    A       V  + 
Sbjct: 471 FGFIHQAGVYPLAADISHVIATKPAATHVHLIT 503
 Score = 45.0 bits (106), Expect = 0.003
 Identities = 25/166 (15%), Positives = 52/166 (31%), Gaps = 21/166 (12%)

Query: 52  ALAFRAANALLVRT-YFNPDEHWQCLEVAHRIVFGYGH-LTWEW--KRGLRSYLHP-FIF 106
             A R     + +  Y +PDE +Q +EV     F   H  TWE+     +RS + P  + 
Sbjct: 23  FAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALL 82

Query: 107 AALYKILSL----------LHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVA 156
              +               L L   +   + PRL+ ++ +   D  L++    ++     
Sbjct: 83  RIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLRFE 141

Query: 157 HMETVLTVTGLYYWFVAIESVKGNSVV----SKQQAASKQSPPSRK 198
                +  +          +   +  +          S+    +  
Sbjct: 142 IRLLAMG-SSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNT 186
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 197

 Score =  130 bits (326), Expect = 5e-29
 Identities = 33/197 (16%), Positives = 78/197 (38%), Gaps = 4/197 (2%)

Query: 152 NNHVAHMETVLTVTGLYYWFVAIESVKG-NSVVSKQQAASKQSPPSRKMALLIAAL-ACA 209
                 +  + +    +  +     +     +++   + S     +   ++ I    A  
Sbjct: 1   GTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKNNYYGSISILVFAAAI 60

Query: 210 IRPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNF 269
           +R   A+  + + L   +Q +     + L  +   +  +  +  +D + +G+     L  
Sbjct: 61  VRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWPELEA 120

Query: 270 LKFNLFSSGGDYYGTHVFHWYFSQG-FPSMIWTFLPFSISGILKSREWRLAGL-IVWVLV 327
             FN+       +GT  F++YF +  +  +  T L F +   +  +  RL     ++ + 
Sbjct: 121 FLFNVVEGKSSDWGTSPFYYYFVRLPWLFLNPTTLLFLLISFVYIKPARLLIYVPLFFIF 180

Query: 328 VYSILGHKEFRFVLPVL 344
           VYS LGHKE+RF++  +
Sbjct: 181 VYSFLGHKEWRFIIYSI 197
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
          Length = 283

 Score =  127 bits (317), Expect = 5e-28
 Identities = 42/203 (20%), Positives = 81/203 (39%), Gaps = 31/203 (15%)

Query: 210 IRPTSAITWLYVGLLDFIQMKSKSRFIFLEVVP---------LGVFVLAVTTFLDCWMYG 260
           +R T  +    V              +    VP             V         W + 
Sbjct: 65  MRTTLRLLAKLVVFRCI-----SVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHS 119

Query: 261 SRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAG 320
            R       + FN+   G   +G H ++WY   G P+++   +   I G+L    +R + 
Sbjct: 120 LRSFFHPALIAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSL 179

Query: 321 LIVW----VLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLK 376
           L  +     ++V+S+L HKE RF+LP++P + +++G     + + +              
Sbjct: 180 LPFFATITYIIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWR-------------G 226

Query: 377 LSVILLILTNVPMALYMSLYHQR 399
            ++ ++I  N+ +AL+ S YHQ+
Sbjct: 227 SAMAVMIAINIGIALFTSRYHQK 249
 Score = 92.9 bits (229), Expect = 1e-17
 Identities = 34/86 (39%), Positives = 51/86 (58%), Gaps = 1/86 (1%)

Query: 41  ALGSERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSY 100
            + +  R+LA  + FR  +  LV ++F PDE +Q  EVAH +V+G GHL+WEW+  LRS+
Sbjct: 64  RMRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSF 123

Query: 101 LHPFIFAA-LYKILSLLHLDSPWFMA 125
            HP + A  + +  S L    PW+  
Sbjct: 124 FHPALIAFNVVQGGSALFGVHPWYWY 149
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
           chromosome I precursor [Leishmania major]
          Length = 822

 Score =  123 bits (307), Expect = 7e-27
 Identities = 30/161 (18%), Positives = 61/161 (37%), Gaps = 6/161 (3%)

Query: 49  LALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEW--KRGLRSYLHPFIF 106
           L L+L    A++ L     + DE +  +E  H +++G G  TWE   +  LRS+L  +I 
Sbjct: 16  LLLSLTHYFASSFLP--ISDCDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSWLFLWIH 73

Query: 107 AALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTG 166
           A    ++      S   +    R+L    A+  +L+         +   A +  +L +  
Sbjct: 74  AWPVVLIRGAASLSSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLLAN 133

Query: 167 L--YYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAA 205
               +  V++       + +     S     S   +  + +
Sbjct: 134 YPIQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLS 174
 Score = 76.2 bits (186), Expect = 1e-12
 Identities = 19/105 (18%), Positives = 36/105 (34%), Gaps = 9/105 (8%)

Query: 199 MALLIAALACA-IRPTSAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFL-DC 256
            AL  + LA     P +A+    VGL   ++   +     L      + V     F+ D 
Sbjct: 230 AALCFSVLAVVTGWPFAALISALVGLDLLLRFPVR----TLACTLGSLLVACAAVFVADV 285

Query: 257 WMYGSRIIVPLNFLKFNLFSS---GGDYYGTHVFHWYFSQGFPSM 298
             Y    +   N + +N F     G + +G     +++     + 
Sbjct: 286 RYYCRWTLSSWNVVMYNGFGGSGRGPELFGVEPIFFFWKNLMLNF 330
 Score = 40.7 bits (95), Expect = 0.052
 Identities = 15/40 (37%), Positives = 19/40 (47%), Gaps = 1/40 (2%)

Query: 316 WRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNL 355
             +    VW L   SI  HKE RF+ P  PFM + +   L
Sbjct: 437 LHIMPFFVWFLFWMSI-AHKEERFMSPAYPFMLLAATRTL 475
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
 gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
           [Caenorhabditis elegans]
          Length = 232

 Score =  120 bits (300), Expect = 5e-26
 Identities = 42/203 (20%), Positives = 81/203 (39%), Gaps = 31/203 (15%)

Query: 210 IRPTSAITWLYVGLLDFIQMKSKSRFIFLEVVP---------LGVFVLAVTTFLDCWMYG 260
           +R T  +    V              +    VP             V         W + 
Sbjct: 1   MRTTLRLLAKLVVFRCI-----SVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHS 55

Query: 261 SRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAG 320
            R       + FN+   G   +G H ++WY   G P+++   +   I G+L    +R + 
Sbjct: 56  LRSFFHPALIAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSL 115

Query: 321 LIVW----VLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLK 376
           L  +     ++V+S+L HKE RF+LP++P + +++G     + + +              
Sbjct: 116 LPFFATITYIIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWR-------------G 162

Query: 377 LSVILLILTNVPMALYMSLYHQR 399
            ++ ++I  N+ +AL+ S YHQ+
Sbjct: 163 SAMAVMIAINIGIALFTSRYHQK 185
 Score = 88.2 bits (217), Expect = 3e-16
 Identities = 34/85 (40%), Positives = 51/85 (60%), Gaps = 1/85 (1%)

Query: 42  LGSERRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYL 101
           + +  R+LA  + FR  +  LV ++F PDE +Q  EVAH +V+G GHL+WEW+  LRS+ 
Sbjct: 1   MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFF 60

Query: 102 HPFIFAA-LYKILSLLHLDSPWFMA 125
           HP + A  + +  S L    PW+  
Sbjct: 61  HPALIAFNVVQGGSALFGVHPWYWY 85
>ref|NP_441044.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
 pir||S77166 hypothetical protein sll2003 - Synechocystis sp. (strain PCC 6803)
 dbj|BAA17724.1| (D90908) ORF_ID:sll2003~unknown protein [Synechocystis sp. PCC
           6803]
          Length = 443

 Score = 42.3 bits (99), Expect = 0.020
 Identities = 42/304 (13%), Positives = 92/304 (29%), Gaps = 39/304 (12%)

Query: 126 MAPRLLQSVFASFGDLYLYKLSKLIFNN-HVAHMETVLTVTGLYYWFVAIESVKGNSVVS 184
            + RL  ++ ++     LY L K IF++   A   + + +T L    +   ++    + +
Sbjct: 13  FSSRLPLALGSALAVPLLYLLGKEIFSSPRAALWSSSILLTLLPTARLGRLTMLDGVINA 72

Query: 185 KQQAASKQSPPSRK---------MALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRF 235
               +       RK         + L + ALA  +   +    L + +    + +   R+
Sbjct: 73  CLLWSLLCLLRGRKNPHWLGGIGIGLGLIALAKGLLVLALALLLGIVIFWLGEGRIFQRW 132

Query: 236 IFLEVVPLGVFVLAVTTFLDCWMYGSRIIV---------PLNFLKFNLFSSGGDYYGTHV 286
            F   + +G              +                  F  F   +   +      
Sbjct: 133 QFWLGLLIGFA--------PVLWWYQLQFAEYGETFWQIHFEFHSFERVTQELEGNTGPP 184

Query: 287 FHWYFSQGFPSMIWTFLPFSISGILKSREWRLAG-----LIVWVLVVYSILGHKEFRFVL 341
           +++       +  W F     + +   +  +             L++ S +G K   +VL
Sbjct: 185 WYYLLEIVKYTAPWLFFLIPAAVMTVQQWRQDWAKVAITFGFGFLLIISAMGTKLPWYVL 244

Query: 342 PVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLYHQRGT 401
           P  PF  +  G+ LA +                +   + L  +  +   LY     Q+  
Sbjct: 245 PCYPFFALMGGYYLADL-------EGRPRYPRLIGYLLALTAVVGLVGGLYAGFIEQKPV 297

Query: 402 EDAM 405
              M
Sbjct: 298 IIIM 301
>ref|NP_213845.1| (NC_000918) hypothetical protein [Aquifex aeolicus]
 pir||F70406 conserved hypothetical protein aq_1236 - Aquifex aeolicus
 gb|AAC07253.1| (AE000730) hypothetical protein [Aquifex aeolicus]
          Length = 468

 Score = 40.3 bits (94), Expect = 0.082
 Identities = 48/319 (15%), Positives = 92/319 (28%), Gaps = 29/319 (9%)

Query: 103 PFIFAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVL 162
           P +F     I S          A A  +  ++  +F   +         N   A + +V 
Sbjct: 57  PPLFNWFIIISSKFFGWD-IVTARAVSVFFTLANAFLIYFFSSKVLK--NKEKALLSSVF 113

Query: 163 TVT-----GLYYWFVAIESVKGNSVVSKQQAASKQSPP----SRKMALLIAALACAIRPT 213
            +T       Y W   I+      V        K            + L+  L   I+  
Sbjct: 114 FITFADVLFWYGWLAEIDVTLSFFVTLLFIQIYKLWEEGKPIYYYTSALLTGLIFMIKGF 173

Query: 214 SAITWLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFN 273
            A  +  + L+     K   + +         F+  + +F       +        L   
Sbjct: 174 PAFAFYGLSLISLSIFKRDFKVLLNFHAFASYFLALIASFWWLPFSENPEF-YFRRLWEE 232

Query: 274 LFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAG---------LIVW 324
            FS          F  +        +   LP S+  I      R++          L+++
Sbjct: 233 SFSRVESSKDLEKFLIHLITYPLLNVKQLLPASLFVIPLIFTKRISLPRELKFLLFLVIF 292

Query: 325 VLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLIL 384
             + Y I      R+VLP+ P +        A +       + +K     L   + ++IL
Sbjct: 293 NYIPYIISATSRGRYVLPLFPIL----AVIFAHLIHEYLSKNWKKVL---LFSLIFVIIL 345

Query: 385 TNVPMALYMSLYHQRGTED 403
             +    ++   + R  E 
Sbjct: 346 RFIYGIFFLPYVNHRKGEP 364
>ref|NP_214167.1| (NC_000918) hypothetical protein [Aquifex aeolicus]
 sp|O67601|YH04_AQUAE Hypothetical protein AQ_1704
 gb|AAC07577.1| (AE000752) hypothetical protein [Aquifex aeolicus]
          Length = 416

 Score = 39.6 bits (92), Expect = 0.14
 Identities = 52/286 (18%), Positives = 93/286 (32%), Gaps = 29/286 (10%)

Query: 108 ALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGL 167
            LY + SL  L        + RL+  + A    L +Y ++    +   A +  +     +
Sbjct: 62  MLYWLGSLSFLI-FGISEFSARLISGLSAFGTTLLIYFITLKHVSREKALLSALTFPLFI 120

Query: 168 YYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIA-ALACAIRPTSAITWLYVGLLDF 226
           + W  +   V   ++V             R      A ALA   +    +       L  
Sbjct: 121 HTWIESRAYVPEFTLVFFSTLGVYLFSIDRFTLGWTALALAFLTKGPVGVILPIGIYLL- 179

Query: 227 IQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYY---G 283
              +   +F+  + V L + +         W +   +I    F  F  F    + Y   G
Sbjct: 180 --WRRDLKFLNFKGVLLFILIGF------SWYF--LMIYKFGFNFFFKFFIFENIYRFTG 229

Query: 284 THVFH---WYFSQGFPSMIWTFLPFSISGILKSREWRLAGLIVWVLV---VYSILGHKEF 337
           T+  H    YF      +           ILK  + RL     W L+    YS+  +K  
Sbjct: 230 TYQIHNMPIYFYPLVILVSSILFLPVFLKILKDFDKRLLPFAGWFLLVLVFYSLSKNKLH 289

Query: 338 RFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLI 383
            ++L   P + +  G  L        K + +   +    L +IL+ 
Sbjct: 290 HYILFSYPALSVIIGFYLT-------KRYIKYAYIVGSFLLLILMF 328
>ref|NP_213834.1| (NC_000918) putative protein [Aquifex aeolicus]
 sp|O67270|YC20_AQUAE Hypothetical protein AQ_1220
 pir||C70405 hypothetical protein aq_1220 - Aquifex aeolicus
 gb|AAC07235.1| (AE000729) putative protein [Aquifex aeolicus]
          Length = 499

 Score = 35.3 bits (81), Expect = 2.8
 Identities = 52/340 (15%), Positives = 105/340 (30%), Gaps = 29/340 (8%)

Query: 69  PDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHP---FIFAALYKILSLLHLDSPWFMA 125
           P+E +   + A  ++     LT  +   +R    P   +I +  YKI  +  L   +F  
Sbjct: 28  PNESF-YADSAKNMLKSGEFLTPVYNGEIRLNKPPMTYWIVSLGYKIFGVNELGLRFF-- 84

Query: 126 MAPRLLQSVFASFGDLYLYKLSKLIFNNHVAHMETVLTVTGLY-YWFVAIESVKGNSVVS 184
                L  VF       L +      N  +     +            A   V     ++
Sbjct: 85  ---HALLGVFTGVLTYLLARRITGSKNTALLSFLILSLSFIFIANARYASPEVPFTFFIT 141

Query: 185 KQQAASKQSPPSRKMALLIAALACAI------RPTSAITWLYVGLLDFIQMKSKSRFIFL 238
                  +    +K  L   AL  +        P   +    V     +      + +  
Sbjct: 142 LSLYLWYEYFTRKKEFLFWLALIASSLAVLTKGPAGFVLPAGVVFFYLLLRA--PKELLK 199

Query: 239 EVVPLGVFVLAVTTFLDCWMYGSRII---VPLNFLKFNLFSSGGDYYGTHVFHWYFSQGF 295
                G  ++ +      ++Y   +        F+K N+            F++Y     
Sbjct: 200 IKYYAGTLMVFL-LSGWWFLYQYLVHREEFLEVFIKENVKRIYALQRD--PFYFYALDIN 256

Query: 296 PSMIWTFLPFSISGILKS--REWRLAGLIVWV---LVVYSILGHKEFRFVLPVLPFMFMF 350
            S +     F  +       +   L+  +VW     +++SI+  K   +++P  P M + 
Sbjct: 257 VSFLPYSFLFFFALFWALKEKRRELSFPLVWFSFIFLIFSIVKMKIPVYIMPAYPAMAII 316

Query: 351 SGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMA 390
           +   L + +  K K  +     + L L+ + L L     A
Sbjct: 317 TADFLNSQSLKKVKNLSLIFLWTVLVLATLALSLYFKFSA 356
CPU time:   165.91 user secs.	    2.90 sys. secs	  168.81 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.316    0.181    0.499 

Gapped
Lambda     K      H
   0.270   0.0634    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 363367779
Number of Sequences: 887402
Number of extensions: 20664773
Number of successful extensions: 97629
Number of sequences better than 10.0: 1374
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 1351
Number of HSP's that attempted gapping in prelim test: 95593
Number of HSP's gapped (non-prelim): 2605
length of query: 506
length of database: 277,845,442
effective HSP length: 53
effective length of query: 453
effective length of database: 230,813,136
effective search space: 104558350608
effective search space used: 104558350608
T: 11
A: 40
X1: 15 ( 6.8 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.7 bits)
S2: 76 (33.6 bits)