Sequences with E-value BETTER than threshold (0.002)
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 600 e-170
ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 438 e-122
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 428 e-118
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 428 e-118
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 426 e-118
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 419 e-116
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 336 8e-91
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 335 1e-90
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 335 2e-90
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 333 4e-90
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 327 4e-88
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 325 9e-88
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 324 3e-87
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 317 3e-85
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 308 3e-82
gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melano... 294 4e-78
emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus mus... 273 6e-72
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 258 1e-67
ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo ... 257 3e-67
emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-... 256 8e-67
gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 252 1e-65
ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans] ... 252 1e-65
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 248 2e-64
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 247 4e-64
ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Sacch... 243 4e-63
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 243 6e-63
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 242 1e-62
pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans 236 7e-61
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 236 8e-61
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 234 3e-60
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 234 4e-60
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 230 5e-59
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 228 1e-58
pir||T39659 cell wall biosynthesis protein N3265 homolog - fissi... 225 2e-57
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 201 3e-50
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 184 4e-45
gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan ... 180 6e-44
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 177 4e-43
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 139 1e-31
dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharom... 131 2e-29
pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans 129 1e-28
ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]... 123 7e-27
ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. ... 99 2e-19
Sequences with E-value WORSE than threshold
ref|NP_069450.1| (NC_000917) conserved hypothetical protein [Arc... 41 0.061
Alignments
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
Length = 558
Score = 600 bits (1533), Expect = e-170
Identities = 558/558 (100%), Positives = 558/558 (100%)
Query: 1 MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFP 60
MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFP
Sbjct: 1 MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFP 60
Query: 61 AVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAE 120
AVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAE
Sbjct: 61 AVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAE 120
Query: 121 ETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLV 180
ETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLV
Sbjct: 121 ETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLV 180
Query: 181 LLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLI 240
LLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLI
Sbjct: 181 LLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLI 240
Query: 241 VLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPH 300
VLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPH
Sbjct: 241 VLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPH 300
Query: 301 VLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITA 360
VLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITA
Sbjct: 301 VLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITA 360
Query: 361 AFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIA 420
AFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIA
Sbjct: 361 AFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIA 420
Query: 421 TCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSF 480
TCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSF
Sbjct: 421 TCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSF 480
Query: 481 NMSDLEESRKASELQSVVMPKSAPHPDAMVMTRAVAKEIEEPFLKRHGYRLYRTFLHSPL 540
NMSDLEESRKASELQSVVMPKSAPHPDAMVMTRAVAKEIEEPFLKRHGYRLYRTFLHSPL
Sbjct: 481 NMSDLEESRKASELQSVVMPKSAPHPDAMVMTRAVAKEIEEPFLKRHGYRLYRTFLHSPL 540
Query: 541 TLAPYEDIYIQMWVKVTK 558
TLAPYEDIYIQMWVKVTK
Sbjct: 541 TLAPYEDIYIQMWVKVTK 558
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase -like protein [Arabidopsis
thaliana]
gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
Length = 548
Score = 438 bits (1117), Expect = e-122
Identities = 120/527 (22%), Positives = 217/527 (40%), Gaps = 97/527 (18%)
Query: 2 PWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPA 61
P + +R+ I+T PDE WQS EVA+ +FG G++ WEW+ G+RS L P
Sbjct: 38 PRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPM 97
Query: 62 VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121
+ A + LL++ G DT + + APR++Q++ + D+ ++ +
Sbjct: 98 LFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKL------------------ 139
Query: 122 TRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVL 181
S +++ +L ++NW++ +C R + N +E +L +
Sbjct: 140 -------------------SDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
Query: 182 LTLQQRRYVPFLL------------LTGLASAIRVTSAVVLSPLVFRHLANATREHGFIR 229
+ L + + LA AIR TSAV+ + L + FI
Sbjct: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFI- 239
Query: 230 GLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYV 289
+L + + VLG +LD YG WV+ PL F +FN L + ++G HPW++Y
Sbjct: 240 -----ILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYF 294
Query: 290 GPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFV 349
+ ++ F+IA + + ++ +S + W L YS++ HKE RFV
Sbjct: 295 TQGFLVMLFTFTPFSIAGII----KSKNQKLSA-------LILWVLAIYSILGHKEFRFV 343
Query: 350 FVVIPLSLITAAFVLVRW----------------------SRTSAVVVKMNRLFVLFNIV 387
V+P++LI + + + ++ S + + NI
Sbjct: 344 LPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIP 403
Query: 388 MIYLMGYVYRRGPLDVMAEVRDGP---RINRLDVIATCYTVPGYSYMHKKVNHLGFVDCS 444
M M ++RG D M + D R+ + + C++ P YS +H+ + + F+DC+
Sbjct: 404 MALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIP-MQFLDCT 462
Query: 445 IDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHS-FNMSDLEESRK 490
++ + E F P + + L S +
Sbjct: 463 PSAEKGE----LDESDQFLVNPLGFASELARNWSEPPSHIVLFASEE 505
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
GPI-anchor biosynthesis [Mus musculus]
dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
Length = 542
Score = 428 bits (1090), Expect = e-118
Identities = 129/498 (25%), Positives = 213/498 (41%), Gaps = 73/498 (14%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
+L+ T R+ C ++T PDE+WQS EVA+ MVF G+L WEW LR +P +
Sbjct: 51 YLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIF 110
Query: 64 ALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETR 123
A + +L LLG+D+ + + PR+ QAL+ + D+ ++ +
Sbjct: 111 ASIYKVLHLLGKDSVQFLIWIPRLGQALLSAVADIRLYSLL------------------- 151
Query: 124 QSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLT 183
++ ++ L L +W+ YC R N +E L L
Sbjct: 152 ------------------KQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTALA 193
Query: 184 LQQR--------RYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIV 235
L + + LL LA +R T+ + PL+FRH R+ L +
Sbjct: 194 LFYYPLEGSRSVNSIKYSLLVALACVVRPTALIPWVPLLFRHFYQEQRKLHL--TLHHFL 251
Query: 236 LTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVG 295
G I L ++D F+G+W L L F +FNVL NL F+G HPW++Y+
Sbjct: 252 PVGFITFSLSL----IIDRIFFGQWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPV 307
Query: 296 IVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPL 355
++G H+ F I + R + +L WTL YS++ HKE RF++ V+P
Sbjct: 308 VLGTHLPFFIHGCFL---------APRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPF 358
Query: 356 SLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDG----- 410
++ + L +L N+ + + G V++RG LDVM ++
Sbjct: 359 CMVFCGYSLAHLKTWR---KAALSFLLLSNVPLAFYTGLVHQRGTLDVMNHIQKVCPRGP 415
Query: 411 -PRINRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEY 469
P + ++ C++ P YS++H ++ + F+ C DL KT + E MF P +
Sbjct: 416 DPASASVFIMMPCHSTPYYSHVHCPLS-MRFLQCPPDLTGKTQY--LDEADMFYLNPLRW 472
Query: 470 VLWRYDGKHS-FNMSDLE 486
+ + S
Sbjct: 473 LQQEFHSNASLPTHLVTF 490
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
Length = 554
Score = 428 bits (1089), Expect = e-118
Identities = 127/498 (25%), Positives = 213/498 (42%), Gaps = 73/498 (14%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
+L+ T R+ C ++T PDE+WQS EV+++MVF G+L WEW LRS +P +
Sbjct: 62 YLLLFTLALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIF 121
Query: 64 ALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETR 123
A + +L LLG+D+ + + PR+ QAL+ + DV ++ +
Sbjct: 122 ASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSL-------------------- 161
Query: 124 QSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLT 183
++ ++ L +W+ YC R N +E +L ++
Sbjct: 162 -----------------MKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIA 204
Query: 184 LQQR--------RYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIV 235
L V + L LA IR T+ ++ +PL+FRH R+ I L +
Sbjct: 205 LFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLI--LHHFL 262
Query: 236 LTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVG 295
G + L L ++D F+G+W L F +FNVL NL F+G HPW++Y
Sbjct: 263 PVGFVTLSLSL----MIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPV 318
Query: 296 IVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPL 355
I+G H+ F I + +L WTL YS++ HKE RF++ V+P
Sbjct: 319 ILGTHLPFFIHGC---------YLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPF 369
Query: 356 SLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVR----DGP 411
++ + L L N+ + G V++RG LDVM+ ++ + P
Sbjct: 370 CMVFCGYSLTHLKTWK---KPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNP 426
Query: 412 RI--NRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEY 469
+ ++ C++ P YS++H + + F+ C DL K+ + E +F P +
Sbjct: 427 NKSSASIFIMMPCHSTPYYSHVHCPLP-MRFLQCPPDLTGKSHY--LDEADVFYLNPLNW 483
Query: 470 VLWRYDGKHS-FNMSDLE 486
+ S
Sbjct: 484 SHREFHDDASLPTHLITF 501
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
(EC 2.4.1.130) PIGB - human
dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
Length = 554
Score = 426 bits (1085), Expect = e-118
Identities = 126/498 (25%), Positives = 213/498 (42%), Gaps = 73/498 (14%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
+L+ T R+ C ++T PDE+WQS EV+++MVF G+L WEW LRS +P +
Sbjct: 62 YLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIF 121
Query: 64 ALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETR 123
A + +L LLG+D+ + + PR+ QAL+ + DV ++ +
Sbjct: 122 ASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSL-------------------- 161
Query: 124 QSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLT 183
++ ++ L +W+ YC R N +E +L ++
Sbjct: 162 -----------------MKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTIIA 204
Query: 184 LQQR--------RYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIV 235
L V + L LA IR T+ ++ +PL+FRH R+ I L +
Sbjct: 205 LFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWTPLLFRHFCQEPRKLDLI--LHHFL 262
Query: 236 LTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVG 295
G + L L ++D F+G+W L F +FNVL N F+G HPW++Y
Sbjct: 263 PVGFVTLSLSL----MIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPV 318
Query: 296 IVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPL 355
I+G H+ F I + +L WTL YS++ HKE RF++ V+P
Sbjct: 319 ILGTHLPFFIHGC---------YLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPF 369
Query: 356 SLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVR----DGP 411
++ + L L N+ + G V++RG LDVM+ ++ + P
Sbjct: 370 CMVFCGYSLTHLKTWK---KPALSFLFLSNLFLALYTGLVHQRGTLDVMSHIQKVCYNNP 426
Query: 412 RI--NRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEY 469
+ ++ C++ P YS++H + + F+ C DL K+ + E +F P +
Sbjct: 427 NKSSASIFIMMPCHSTPYYSHVHCPLP-MRFLQCPPDLTGKSHY--LDEADVFYLNPLNW 483
Query: 470 VLWRYDGKHS-FNMSDLE 486
+ + S
Sbjct: 484 LHREFHDDASLPTHLITF 501
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein - Arabidopsis
thaliana
emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein [Arabidopsis
thaliana]
Length = 498
Score = 419 bits (1068), Expect = e-116
Identities = 116/515 (22%), Positives = 207/515 (39%), Gaps = 96/515 (18%)
Query: 2 PWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPA 61
P + +R+ I+T PDE WQS EVA+ +FG G++ WEW+ G+RS L P
Sbjct: 38 PRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPM 97
Query: 62 VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121
+ A + LL++ G DT + + APR++Q++ + D+ ++ +
Sbjct: 98 LFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKL------------------ 139
Query: 122 TRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVL 181
S +++ + +L++ Y C
Sbjct: 140 -------------------SDALYGGNVATWSTVLTIMGLYYWPCIRD----------SS 170
Query: 182 LTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIV 241
+ R L++ LA AIR TSAV+ + L + FI +L + +
Sbjct: 171 IDYPVNRKWG-LVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFI------ILEVIPI 223
Query: 242 LVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHV 301
VLG +LD YG WV+ PL F +FN L + ++G HPW++Y + ++
Sbjct: 224 GSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFT 283
Query: 302 LFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAA 361
F+IA + + ++ +S + W L YS++ HKE RFV V+P++LI +
Sbjct: 284 PFSIAGII----KSKNQKLSA-------LILWVLAIYSILGHKEFRFVLPVLPIALIFSG 332
Query: 362 FVLVRW----------------------SRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRG 399
+ + ++ S + + NI M M ++RG
Sbjct: 333 YAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRG 392
Query: 400 PLDVMAEVRDGP---RINRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKV 456
D M + D R+ + + C++ P YS +H+ + + F+DC+ ++ +
Sbjct: 393 TEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIP-MQFLDCTPSAEKGE----L 447
Query: 457 TEDIMFRRYPKEYVLWRYDGKHS-FNMSDLEESRK 490
E F P + + L S +
Sbjct: 448 DESDQFLVNPLGFASELARNWSEPPSHIVLFASEE 482
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
Length = 611
Score = 336 bits (853), Expect = 8e-91
Identities = 93/445 (20%), Positives = 154/445 (33%), Gaps = 77/445 (17%)
Query: 9 TFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAVVALP 66
RL + DE + E + +++G+G WE+ Y +RS + + A P
Sbjct: 65 LLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWP 123
Query: 67 FYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSK 126
+ + V++ R L A V C + K L ++
Sbjct: 124 AAFHARILQTNKILVFYFLRCLLAFVS------CICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 127 TKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQ 186
FC S + +S L++++ WYM + + G A+L
Sbjct: 178 VLSTGMFCSSSAF-----LPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGW----- 227
Query: 187 RRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVL 246
SA + P+ F L R F L+ L+ L
Sbjct: 228 -----------------PFSAALGLPIAFDLLVMKHRWKSFFH-------WSLMALILFL 263
Query: 247 GGVMVLDYCFYGRWVLTPLAFFRFNVL-HNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTI 305
V+V+D +YG+ V+ PL +NV + +G PWYFY ++ G + +V F +
Sbjct: 264 VPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFY---LINGFLNFNVAFAL 320
Query: 306 AAPLVLWRDTASRAVSRPVLGMLGIGAW--------TLGFYSLIDHKEMRFVFVVIPLSL 357
A ++ + R + LG W + + HKE RF+F V PL
Sbjct: 321 ALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLIC 380
Query: 358 ITAAFVLVRWSRTSAVVVKMNRL---------FVLFNIVMIYLMGYVYR-------RGPL 401
+ A L + V + RL L + + L+ + GPL
Sbjct: 381 LCGAVALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGYHGPL 440
Query: 402 DVMAEVRDGPRINRLDVIATCYTVP 426
D+ P R+ T +TVP
Sbjct: 441 DLY------PEFYRIATDPTIHTVP 459
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
musculus]
Length = 611
Score = 335 bits (851), Expect = 1e-90
Identities = 96/445 (21%), Positives = 156/445 (34%), Gaps = 77/445 (17%)
Query: 9 TFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAVVALP 66
RL + DE + E + +++GKG WE+ Y +RS + + A P
Sbjct: 65 LLSARLCAALL-SNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWP 123
Query: 67 FYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSK 126
+ + V++ R L A V C + K L ++
Sbjct: 124 AAFHARILQTNKILVFYFLRCLLAFVS------CVCELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 127 TKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQ 186
FC S + +S L++++ WYM + + G A+L
Sbjct: 178 VLSTGMFCSSSAF-----LPSSFCMYTTLIAMTGWYMDKTPIAVLGVAAGAILGW----- 227
Query: 187 RRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVL 246
SA + P+ F LA R F +L L+ L L
Sbjct: 228 -----------------PFSAALGLPIAFDLLARKHRWKSF-------LLWSLVALALFL 263
Query: 247 GGVMVLDYCFYGRWVLTPLAFFRFNVL-HNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTI 305
V+V+D +YG+ V+ PL +NV + +G PWYFY ++ G + +V F +
Sbjct: 264 VPVVVIDSYYYGKLVVAPLNIVLYNVFTSHGPDLYGTEPWYFY---LINGFLNFNVAFAL 320
Query: 306 AAPLVLWRDTASRAVSRPVLGMLGIGAW--------TLGFYSLIDHKEMRFVFVVIPLSL 357
A ++ + R + LG W + + HKE RF+F V PL
Sbjct: 321 ALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLIC 380
Query: 358 ITAAFVLVRWSRTSAVVVKMNRL---------FVLFNIVMIYLMGYVYR-------RGPL 401
+ A L + V + RL L + + L+ + GPL
Sbjct: 381 LCGAVALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGYHGPL 440
Query: 402 DVMAEVRDGPRINRLDVIATCYTVP 426
D+ P R+ T +TVP
Sbjct: 441 DLY------PEFYRIATDPTIHTVP 459
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
(Schizosaccharomyces pombe)
emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
[Schizosaccharomyces pombe]
Length = 506
Score = 335 bits (851), Expect = 2e-90
Identities = 118/526 (22%), Positives = 197/526 (37%), Gaps = 99/526 (18%)
Query: 1 MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFP 60
M W ++R + ++T PDE++QS EVA++ +F G L WEW +RS L P
Sbjct: 1 MRIWFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHP 60
Query: 61 AVVALPFYLLKLLGRDTTWAVWF-APRVLQALVLTLIDVSVFCMGATLDELLAKRELELA 119
+ A + +L++L D+++ V+ AP++LQ ++D +
Sbjct: 61 LIFAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFA--------------- 105
Query: 120 EETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALL 179
+ + L SL + AY GVR + N +E L
Sbjct: 106 ----------------------LVRYGSKTANWTLACSLVSIMNAYVGVRTFSNSLETTL 143
Query: 180 VLLTLQQRRY-------------------VPFLLLTGLASAIRVTSAVVL-SPLVFRH-- 217
+ Y + F+ + A IR T+ +V PL+F +
Sbjct: 144 TSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAFACFIRPTNILVWIFPLLFWNKN 203
Query: 218 ----------LANATREHGFIRGLFRIVLTGLIVLVAVLGGV-MVLDYCFYGRWVLTPLA 266
+N F+ L L G+ VL L V ++ D YGR+V ++
Sbjct: 204 PQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVSLFLVNIIADRILYGRFVFPIIS 263
Query: 267 FFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLG 326
FF+FNV LS +G + W++Y+ L I G + F + L
Sbjct: 264 FFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPFVLLTMD---------------LQ 308
Query: 327 MLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNI 386
G YSLI HKE+RFV+ + P+ L A +S + L L +
Sbjct: 309 TAGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFFSSFSSWK-RAARFFFLIGLGHA 367
Query: 387 VMIYLMGYVYRRGPLDVMAEVRDGPRINRL-DVIATCYTVPGYSYMHKKV--NHLGFVDC 443
++I + ++ G ++VM + N+ ++A C+T P S++H N F+ C
Sbjct: 368 LVITFLCRFHQFGVMEVMPLIHSLAEKNQTGLILAPCHTTPWQSHIHSPFAENGWKFLTC 427
Query: 444 SIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSFNMSDLEESR 489
E F ++ K + E R
Sbjct: 428 EPFE------KPFDETDRFYENMPTFLDKI---KEWPDYLIFFEER 464
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
Length = 611
Score = 333 bits (847), Expect = 4e-90
Identities = 93/445 (20%), Positives = 154/445 (33%), Gaps = 77/445 (17%)
Query: 9 TFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAVVALP 66
RL + DE + E + +++G+G WE+ Y +RS + + A P
Sbjct: 65 LLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWP 123
Query: 67 FYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSK 126
+ + V++ R L A V C + K L ++
Sbjct: 124 AAFHARILQTNKILVFYFLRCLLAFVS------CICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 127 TKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQ 186
FC S + +S L++++ WYM + + G A+L
Sbjct: 178 VLSTGMFCSSSAF-----LPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGW----- 227
Query: 187 RRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVL 246
SA + P+ F L R F L+ L+ L
Sbjct: 228 -----------------PFSAALGLPIAFDLLVMKHRWKSFFH-------WSLMALILFL 263
Query: 247 GGVMVLDYCFYGRWVLTPLAFFRFNVL-HNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTI 305
V+V+D +YG+ V+ PL +NV + +G PWYFY ++ G + +V F +
Sbjct: 264 VPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFY---LIKGFLNFNVAFAL 320
Query: 306 AAPLVLWRDTASRAVSRPVLGMLGIGAW--------TLGFYSLIDHKEMRFVFVVIPLSL 357
A ++ + R + LG W + + HKE RF+F V PL
Sbjct: 321 ALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLIC 380
Query: 358 ITAAFVLVRWSRTSAVVVKMNRL---------FVLFNIVMIYLMGYVYR-------RGPL 401
+ A L + V + RL L + + L+ + GPL
Sbjct: 381 LCGAVALSALQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALFRGYHGPL 440
Query: 402 DVMAEVRDGPRINRLDVIATCYTVP 426
D+ P R+ T +TVP
Sbjct: 441 DLY------PEFYRIATDPTIHTVP 459
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
Length = 618
Score = 327 bits (830), Expect = 4e-88
Identities = 93/452 (20%), Positives = 154/452 (33%), Gaps = 84/452 (18%)
Query: 9 TFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAVVALP 66
RL + DE + E + +++G+G WE+ Y +RS + + A P
Sbjct: 65 LLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWP 123
Query: 67 FYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSK 126
+ + V++ R L A V C + K L ++
Sbjct: 124 AAFHARILQTNKILVFYFLRCLLAFVS------CICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 127 TKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQ 186
FC S + +S L++++ WYM + + G A+L
Sbjct: 178 VLSTGMFCSSSAF-----LPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGW----- 227
Query: 187 RRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVL 246
SA + P+ F L R F L+ L+ L
Sbjct: 228 -----------------PFSAALGLPIAFDLLVMKHRWKSFFH-------WSLMALILFL 263
Query: 247 GGVMVLDYCFYGRWVLTPLAFFRFNVL-HNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTI 305
V+V+D +YG+ V+ PL +NV + +G PWYFY ++ G + +V F +
Sbjct: 264 VPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFY---LINGFLNFNVAFAL 320
Query: 306 AAPLVLWRDTASRAVSRPVLGMLGIGAW--------TLGFYSLIDHKEMRFVFVVIPLSL 357
A ++ + R + LG W + + HKE RF+F V PL
Sbjct: 321 ALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLIC 380
Query: 358 ITAAFVLVRW-------SRTSAVVVKMNRL---------FVLFNIVMIYLMGYVYR---- 397
+ A L + V + RL L + + L+ +
Sbjct: 381 LCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALF 440
Query: 398 ---RGPLDVMAEVRDGPRINRLDVIATCYTVP 426
GPLD+ P R+ T +TVP
Sbjct: 441 RGYHGPLDLY------PEFYRIATDPTIHTVP 466
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
Length = 618
Score = 325 bits (827), Expect = 9e-88
Identities = 92/452 (20%), Positives = 154/452 (33%), Gaps = 84/452 (18%)
Query: 9 TFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAVVALP 66
RL + DE + E + +++G+G WE+ Y +RS + + A P
Sbjct: 65 LLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWP 123
Query: 67 FYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSK 126
+ + V++ R L A V C + K L ++
Sbjct: 124 AAFHARILQTNKILVFYFLRCLLAFVS------CICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 127 TKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQ 186
FC S + +S L++++ WYM + + G A+L
Sbjct: 178 VLSTGMFCSSSAF-----LPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGW----- 227
Query: 187 RRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVL 246
SA + P+ F L R F L+ L+ L
Sbjct: 228 -----------------PFSAALGLPIAFDLLVMKHRWKSFFH-------WSLMALILFL 263
Query: 247 GGVMVLDYCFYGRWVLTPLAFFRFNVL-HNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTI 305
V+V+D +YG+ V+ PL +N+ + +G PWYFY ++ G + +V F +
Sbjct: 264 VPVVVIDSYYYGKLVIAPLNIVLYNIFTPHGPDLYGTEPWYFY---LINGFLNFNVAFAL 320
Query: 306 AAPLVLWRDTASRAVSRPVLGMLGIGAW--------TLGFYSLIDHKEMRFVFVVIPLSL 357
A ++ + R + LG W + + HKE RF+F V PL
Sbjct: 321 ALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFFIQPHKEERFLFPVYPLIC 380
Query: 358 ITAAFVLVRW-------SRTSAVVVKMNRL---------FVLFNIVMIYLMGYVYR---- 397
+ A L + V + RL L + + L+ +
Sbjct: 381 LCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVFLFGLLSFSRSVALF 440
Query: 398 ---RGPLDVMAEVRDGPRINRLDVIATCYTVP 426
GPLD+ P R+ T +TVP
Sbjct: 441 RGYHGPLDLY------PEFYRIATDPTIHTVP 466
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
Length = 512
Score = 324 bits (823), Expect = 3e-87
Identities = 99/436 (22%), Positives = 180/436 (40%), Gaps = 39/436 (8%)
Query: 79 WAVWFAPRVLQALVL---TLIDVSV------FCMGATLDELLAKRELELAEETRQSKTKG 129
+ + A R+ V+ + D + L + + G
Sbjct: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAG 66
Query: 130 FSYFCEVSVSRSRRGI--CNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQR 187
+ S + I AL L L W+ Y G R N +EA L + L
Sbjct: 67 LYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYF 126
Query: 188 RY----VPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLV 243
+ +L + +R T+AV+ PL HL +R++ L R VL GL
Sbjct: 127 PWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRR-SRQNVLELILKRFVLIGL---- 181
Query: 244 AVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLF 303
V G + +D ++G+ ++TP F ++N+ +N+ F+G HPW++Y L ++G + L
Sbjct: 182 LVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLP 241
Query: 304 TIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFV 363
I + + + VS+ +L TL S ++HKE RFV ++PL L
Sbjct: 242 FIFGVMETVKKSEKYPVSK---QLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDA 298
Query: 364 LVRWS-RTSAVVVKMNRLFVL-FNIVMIYLMGYVYRRGPLDVMAEVRDGP--------RI 413
L RWS R S+ ++ L +L N++ + + V+++GP+++M ++R+
Sbjct: 299 LSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQ 358
Query: 414 NRLDVIATCYTVPGYSYMHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYV--L 471
+ + C++ P YS++H+ V + F+ C +L++K E F P ++
Sbjct: 359 ANILFLMPCHSTPYYSHIHQNVT-MRFLTCEPNLEKKEQYK--DEADRFFEDPVHWINSH 415
Query: 472 WRYDGKHS-FNMSDLE 486
+ L
Sbjct: 416 IPMHPLTALPTHVVLF 431
Score = 116 bits (289), Expect = 1e-24
Identities = 48/178 (26%), Positives = 79/178 (43%), Gaps = 11/178 (6%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
++ L RL ++T PDE+WQS EVA+ + FG G+L WEW G+RS ++P ++
Sbjct: 5 YVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLI 64
Query: 64 ALPFYLLKLLGRDTTWAVWFAPRVLQ-ALVLTLIDVSVFCMGATLDELLAKRELELAEET 122
A + +L LL D+ + PR+ + AL L L+ F G+ LE + T
Sbjct: 65 AGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLANT----LEASLTT 120
Query: 123 RQSKTKGF-SYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALL 179
+ + + + L LS +++ R NV+E +L
Sbjct: 121 IALSYFPWYGESTAYLWPAAICCFLRPTA-AVIWLPLSLYHLR----RSRQNVLELIL 173
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
Length = 506
Score = 317 bits (806), Expect = 3e-85
Identities = 82/420 (19%), Positives = 155/420 (36%), Gaps = 43/420 (10%)
Query: 86 RVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSKTKGFSYFCEVSVSRSRRGI 145
R + + + L + + +A QS F S+
Sbjct: 98 RSYLHPFIFAALYKILSLLH----LDSPWFMAMAPRLLQSVFASFG--DLYLYKLSKLIF 151
Query: 146 CNSISYTALLLSLSNWYMAYCGVRLYGN--VIEALLVLLTLQQRRYVPFLLLTGLASAIR 203
N +++ +L+++ Y + + V+ LL+ LA AIR
Sbjct: 152 NNHVAHMETVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIR 211
Query: 204 VTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLT 263
TSA+ + + FI L + + V VL LD YG ++
Sbjct: 212 PTSAITWLYVGLLDFIQMKSKSRFI------FLEVVPLGVFVLAVTTFLDCWMYGSRIIV 265
Query: 264 PLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRP 323
PL F +FN+ + ++G H +++Y ++ + F+I+ +
Sbjct: 266 PLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGI-----------LKSR 314
Query: 324 VLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTS----------AV 373
+ G+ W L YS++ HKE RFV V+P + + L ++ +
Sbjct: 315 EWRLAGLIVWVLVVYSILGHKEFRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSR 374
Query: 374 VVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPR---INRLDVIATCYTVPGYSY 430
+ L +L N+ M M ++RG D M + + + + C++ P YS
Sbjct: 375 LKLSVILLILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYST 434
Query: 431 MHKKVNHLGFVDCSIDLDEKTGLPKVTEDIMFRRYPKEYVLWRYDGKHSFNMSDLEESRK 490
+H + + F+DC+ ++ T + E F P ++V + SF+ L ES +
Sbjct: 435 LHYNLP-MRFLDCTPSENKGT----LDESDRFLMNPADFVGEVFGNLSSFSHIVLFESEE 489
Score = 231 bits (584), Expect = 3e-59
Identities = 81/344 (23%), Positives = 139/344 (39%), Gaps = 56/344 (16%)
Query: 3 WWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAV 62
+++L +R +RT PDE WQ EVA+ +VFG GHL WEW+ GLRS L P +
Sbjct: 46 RRVLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFI 105
Query: 63 VALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEET 122
A + +L LL D+ W + APR+LQ++ + D+ ++ +
Sbjct: 106 FAALYKILSLLHLDSPWFMAMAPRLLQSVFASFGDLYLYKL------------------- 146
Query: 123 RQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGN--VIEALLV 180
S+ N +++ +L+++ Y + + V+
Sbjct: 147 ------------------SKLIFNNHVAHMETVLTVTGLYYWFVAIESVKGNSVVSKQQA 188
Query: 181 LLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLI 240
LL+ LA AIR TSA+ + + FI L +
Sbjct: 189 ASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLDFIQMKSKSRFI------FLEVVP 242
Query: 241 VLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPH 300
+ V VL LD YG ++ PL F +FN+ + ++G H +++Y ++
Sbjct: 243 LGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGTHVFHWYFSQGFPSMIWTF 302
Query: 301 VLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHK 344
+ F+I+ + + G+ W L YS++ HK
Sbjct: 303 LPFSISGI-----------LKSREWRLAGLIVWVLVVYSILGHK 335
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
could be the target of the GPI synthesis inhibitor,
YW3548; Most likely an alpha 1,2 mannosyltransferase
utilized for the addition of the third mannose onto the
GPI core structure.; Gpi1>
sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
cerevisiae)
emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
Length = 616
Score = 308 bits (781), Expect = 3e-82
Identities = 90/505 (17%), Positives = 185/505 (35%), Gaps = 75/505 (14%)
Query: 39 MVFGKGHLPWEWRYGLRSVLFPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDV 98
++ K L W+ L+ + F + + + V +AP+++ A++ ++ +
Sbjct: 106 LLLPKYELSWQVAEDLKRLPFDVTRSFEY-----------YGVIYAPKIVMAVLASIGEY 154
Query: 99 SVFCMGATLDELLAKRELELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSL 158
+ L L + E EE R+S + F ALLLSL
Sbjct: 155 YIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKF-------------------ALLLSL 195
Query: 159 SNWYMAYCGVRLYGNVIEALLVLLTLQQR-----------RYVPFLLLTGLASAIRVTSA 207
+N++ + R + N E +L + L + L+ LA R +S
Sbjct: 196 TNFFNCFFITRTFINSFEMILTSIALYYWDWTGGQMIKESSFTKSLIFAFLACLQRPSSG 255
Query: 208 VVLSPL---VFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTP 264
++ + +L + H +++ + +V ++D FY +
Sbjct: 256 LIWVIPSISLILNLVGKKQYHLLFITFSKVLRSFFLVFT----ANAIIDMYFYEKVTFPF 311
Query: 265 LAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLW-RDTASRAVSRP 323
F +FN LS+F+G PW+F+ L ++G + + + + P
Sbjct: 312 FRFLKFNFTTPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNP 371
Query: 324 VLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRW----SRTSAVVVKMNR 379
+ L YS + HKE RF+F + PL ++ ++F L+R + + + +
Sbjct: 372 FFQVKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLDRDYWKRLSGLKSLLW 431
Query: 380 LFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIATCYTVPGYSYMHK-KVNHL 438
L ++ + L+ + G ++VM + + P I+ L I C++ PG SY+H+ + L
Sbjct: 432 LVPFVSVFIALLLDTFHESGSIEVMKFLHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQDL 491
Query: 439 GFVDCSIDLD---EKTGLPKV----TEDIMFRRYPKEYVLWRYDG--------------K 477
+ C+ L + K+ E ++ +
Sbjct: 492 WSITCNPPLHLLGDPEAYSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSH 551
Query: 478 HSFNMSDLEESRKASELQSVVMPKS 502
+ E + + L+ + S
Sbjct: 552 EWPTYLVVFEHMENAFLKDFLKDSS 576
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
Length = 678
Score = 294 bits (745), Expect = 4e-78
Identities = 67/448 (14%), Positives = 151/448 (32%), Gaps = 73/448 (16%)
Query: 9 TFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGL-----RSVLFPAVV 63
I+ + T E + + +++++ + + + R+ + P VV
Sbjct: 3 ILIFVTAAAHLVYTPFTKVEESFNLQAMHDILYLRNNFTQYDHHDYPGVVPRTFIGPLVV 62
Query: 64 ALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETR 123
++ LL + ++A V++ ++ I V+ + + +E+
Sbjct: 63 SIISAPFVLLFETLSINKFWAQYVVRLVLAGAISVAWNSLRQ---AVTKIYGVEV---RL 116
Query: 124 QSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLT 183
+ F + R + N + +L +++ W
Sbjct: 117 WFTAITITQF--HFMFYMTRPLPNIFALPIVLFAIAYWL--------------------- 153
Query: 184 LQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLV 243
+ ++ PF++ +G++ + + + L + + R I GL + L V
Sbjct: 154 --RDQHKPFIICSGISILVFRSE--LALFLGILLVVSLLRRKVSIDGL---LKVALPAGV 206
Query: 244 AVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLF 303
+L +++D F+ R + +N + N S +G P+ +Y L +G ++
Sbjct: 207 CILAATVLVDSFFWRRLLWPEGEVLWYNTVLNKSSNWGTSPFLWYFYSALPRAMGASLVL 266
Query: 304 TIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFV 363
A RP++ + YS++ HKE+RF+ V P+ I AA
Sbjct: 267 VPIGV-------ALEPRIRPLVLSA---LLFVLLYSILPHKELRFIIYVFPVLNIAAACA 316
Query: 364 LVRWSRTSAVVVKMNRLF------VLFNIVMIYL--------------MGYVYR--RGPL 401
R SA + L +L N+ + + ++R G
Sbjct: 317 CQRIWMNSAKSTWHSFLALACGAHLLLNVFITLFLLVISGTNYPGGAALSRLHRLEAGTS 376
Query: 402 DVMAEVRDGPRINRLDVIATCYTVPGYS 429
+V + + + + YS
Sbjct: 377 NVSVHISNLAAQSGVSRFMEINNEWTYS 404
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
Length = 483
Score = 273 bits (692), Expect = 6e-72
Identities = 70/453 (15%), Positives = 134/453 (29%), Gaps = 75/453 (16%)
Query: 2 PWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPA 61
W L + + + E + + ++++
Sbjct: 10 RSWP-LLGLLVTVATIHLVICPYTKVEESFNLQATHDLL--------------------- 47
Query: 62 VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121
++ L + D PR ++ S +L E+ +
Sbjct: 48 -----YHQLDIDKYDHHEFPGVVPRTFLGPLVIAAFSSPVVYVLSLLEVSKFYSQLIVRG 102
Query: 122 TRQSKTKG--FSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALL 179
++ EV R+ +++ +S + +++ + R NV+ +
Sbjct: 103 VLGLGVISGLWTLQKEV-----RQQFGATVAVMFCWISATQFHLMFYCTRTLPNVLALAV 157
Query: 180 VLLTLQQR---RYVPFLLLTGLASA-IRVTSAVVLSPLVFRHLANATREHGFIRGLFRIV 235
VL L R+ F+ L+ R A++L + L R R L +
Sbjct: 158 VLPALTAWLQRRWALFVWLSAFVIIGFRAELAMLLGIALLLTLYQ--RRLTVARVLRHAI 215
Query: 236 LTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVG 295
GL LG + +D F+ V +N + N S +G P +Y L
Sbjct: 216 PAGL----LCLGLTVAVDSYFWRYLVWPEGVVLGYNTVLNKSSNWGTSPLLWYFYSALPR 271
Query: 296 IVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPL 355
+G +LF AV R + + YSL+ HKE+RF+ P+
Sbjct: 272 GLGCSLLFIPLG-----------AVDRRTYALALPSLGFVALYSLLPHKELRFIIYTFPV 320
Query: 356 SLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVM-------IYL-----------MGYVYR 397
I AA + K+ + V +I++ M ++
Sbjct: 321 LNIMAARGCTYILNKKSWPYKVRAMLVTGHILVNVAYTATSLYVSHFNYPGGVAMQQLHE 380
Query: 398 RGP--LDVMAEVRDGPRINRLDVIATCYTVPGY 428
P DV+ + + Y
Sbjct: 381 LVPPQTDVLLHIDVAAAQTGVSRFLQVNDDWRY 413
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
Length = 623
Score = 258 bits (655), Expect = 1e-67
Identities = 60/363 (16%), Positives = 115/363 (31%), Gaps = 51/363 (14%)
Query: 10 FIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAVVALPF 67
RL + DE + E + ++ G G WE+ +GLRS + + +P
Sbjct: 81 VSARLCSAIWAY-IADCDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPG 139
Query: 68 YLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSKT 127
Y + L + +++ R + +++ ++ + + + + +
Sbjct: 140 YFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYK------SICQEFGIHIGRLWLIFQL 193
Query: 128 KGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQR 187
F + + +S S +L+ W+ ++ I ALL
Sbjct: 194 FSVGMFVSSTA-----LLPSSFSMYFGCAALAAWWQQNYCFAIFLTAISALLGW------ 242
Query: 188 RYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLG 247
+A++ PLV L F V LI V
Sbjct: 243 ----------------PFAALIGIPLVLEMLLRQRDWKTF-------VQWTLISGATVAI 279
Query: 248 GVMVLDYCFYGRWVLTPLAFFRFNVL-HNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIA 306
++ +D ++G+ PL +NV + FG P +Y+ + L +
Sbjct: 280 PMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNF-NIIWLLALQ 338
Query: 307 APLVLWRDTASRAVSRPVLGMLGIG------AWTLGFYSLIDHKEMRFVFVVIPLSLITA 360
P++L D L + HKE RF+F + PL +
Sbjct: 339 LPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFFAQPHKEERFLFPIYPLISLCG 398
Query: 361 AFV 363
A
Sbjct: 399 AIT 401
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
Length = 488
Score = 257 bits (652), Expect = 3e-67
Identities = 67/451 (14%), Positives = 134/451 (28%), Gaps = 70/451 (15%)
Query: 3 WWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAV 62
+ L + + + E + + ++++
Sbjct: 9 RRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLL---------------------- 46
Query: 63 VALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEET 122
++ L D PR V+ + S +L E+ +
Sbjct: 47 ----YHWQDLEQYDHLEFPGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGV 102
Query: 123 RQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLL 182
F + RR ++ ++ +++ + R NV+ +VLL
Sbjct: 103 LGLGVI-FGLW--TLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVLL 159
Query: 183 TL---QQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGL 239
L + + F+ L+ A + + L+ R+ +R L V G+
Sbjct: 160 ALAAWLRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGN-RKVSVVRALRHAVPAGI 218
Query: 240 IVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGP 299
LG + +D F+ + +N + N S +G P +Y L +G
Sbjct: 219 ----LCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGC 274
Query: 300 HVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLIT 359
+LF V R + + YSL+ HKE+RF+ P+ IT
Sbjct: 275 SLLFIPLGL-----------VDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNIT 323
Query: 360 AAFVLVRWSRT--SAVVVKMNRLFVLFNIVM-------IYL-----------MGYVYRRG 399
AA + + K L V+ ++V+ M +++
Sbjct: 324 AARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQLV 383
Query: 400 P--LDVMAEVRDGPRINRLDVIATCYTVPGY 428
P DV+ + + + Y
Sbjct: 384 PPQTDVLLHIDVAAAQTGVSRFLQVNSAWRY 414
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
mannosyltransferase [Homo sapiens]
Length = 488
Score = 256 bits (648), Expect = 8e-67
Identities = 67/451 (14%), Positives = 133/451 (28%), Gaps = 70/451 (15%)
Query: 3 WWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAV 62
+ L + + + E + + ++++
Sbjct: 9 RRPLLLGLLVAVATVHLVICPYTKVEESFNLQATHDLL---------------------- 46
Query: 63 VALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEET 122
++ L D PR V+ + S +L E+ +
Sbjct: 47 ----YHWQDLEQYDHLEFPGVVPRTFLGPVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGV 102
Query: 123 RQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLL 182
F + RR ++ ++ +++ R NV+ +VLL
Sbjct: 103 LGLGVI-FGLW--TLQKEVRRHFGAMVATMFCWVTAMQFHLMVYCTRTLPNVLALPVVLL 159
Query: 183 TL---QQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGL 239
L + + F+ L+ A + + L+ R+ +R L V G+
Sbjct: 160 ALAAWLRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGN-RKVSVVRALRHAVPAGI 218
Query: 240 IVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGP 299
LG + +D F+ + +N + N S +G P +Y L +G
Sbjct: 219 ----LCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALPRGLGC 274
Query: 300 HVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLIT 359
+LF V R + + YSL+ HKE+RF+ P+ IT
Sbjct: 275 SLLFIPLGL-----------VDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNIT 323
Query: 360 AAFVLVRWSRT--SAVVVKMNRLFVLFNIVM-------IYL-----------MGYVYRRG 399
AA + + K L V+ ++V+ M +++
Sbjct: 324 AARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQLV 383
Query: 400 P--LDVMAEVRDGPRINRLDVIATCYTVPGY 428
P DV+ + + + Y
Sbjct: 384 PPQTDVLLHIDVAAAQTGVSRFLQVNSAWRY 414
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
Length = 830
Score = 252 bits (639), Expect = 1e-65
Identities = 90/498 (18%), Positives = 173/498 (34%), Gaps = 80/498 (16%)
Query: 11 IYRLFLCATIRT-VEAPDEWWQSTEVAYNMVFGKGH-LPWEWRYGL--RSVLFP-AVVAL 65
RL L + PDE++QS EV F H WE+ L RS++ P A++ +
Sbjct: 25 AVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFALLRI 84
Query: 66 PFYLLKL----------LGRDTTWAVWFAPRVLQALVLTLIDVSVF--CMGATLDELLAK 113
P+ + L T+A PR++ L+ D +F C L +
Sbjct: 85 PWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLYGLRFEIRL 144
Query: 114 RELELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAY-------C 166
+ + T+ FS E+++ + + + ++
Sbjct: 145 LAMGSSWILLVFGTRTFSNSLEMAMCSWLLCLVSECMLRTNTVVYKKEFLEEKYDKAESI 204
Query: 167 GVRLYGNVIEALLVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLV-FRHLANATREH 225
R+ ++ L LQ + + + G+ R T + +P+V F L
Sbjct: 205 SERVRIWKLKNSLPAHNLQHLMAMSTICVAGV--FNRPTFLLFGAPMVFFWLLRGMGTRS 262
Query: 226 GFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYG---------------RWVLTPLAFFRF 270
R + + + L + D +Y +V TP F +
Sbjct: 263 ITFRDFNLRIALFCLCALPALVLFIFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKA 322
Query: 271 NVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTI---AAPLVLWRDTASRAVSRP---V 324
N+ + G HP Y ++ + + L ++ A L+ + + + R V
Sbjct: 323 NLDSAQTASHGVHPCYVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIV 382
Query: 325 LGMLGIGAWTLGFYSLIDHKEMRFVFVV-IPLSLITAAFVLVRWS--------------- 368
M G L F SLI+H+E RF+ V PL L+ A ++ +S
Sbjct: 383 SLMSGAIFVPLFFLSLINHQEPRFLLPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLF 442
Query: 369 -----RTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIATCY 423
+ A + +++ + N+ + G++++ G V D +
Sbjct: 443 YDKLLSSKASGPYLLKIWYVSNVALTLFFGFIHQAG---VYPLAADISHV--------IA 491
Query: 424 TVPGYSYMHKKVNHLGFV 441
T P +++H +H+ +
Sbjct: 492 TKPAATHVHLITSHIYSL 509
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
Length = 492
Score = 252 bits (638), Expect = 1e-65
Identities = 59/380 (15%), Positives = 112/380 (28%), Gaps = 43/380 (11%)
Query: 14 LFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVVALPFYLLKLL 73
+ + I E + + ++++F HLP L
Sbjct: 11 VTIIHIILAPGTKVEESFNVQATHDLMF---HLP----------------------TNLS 45
Query: 74 GRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSKTKGFSYF 133
D + PR + I S + +L L T
Sbjct: 46 NYDHSQFPGVVPRTFIGPISLAILSSPMSFIFRFWAIPKMWQLLLIRATLGLMNA---MA 102
Query: 134 CEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQRRYVPFL 193
R + L+ + ++ + R N +LV++ ++ +
Sbjct: 103 FLYFARSVNRKFGRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYE 162
Query: 194 LLT--GLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVMV 251
AS I +VL + G + G+ + L +
Sbjct: 163 SAVRYATASVILFRCELVLLYGPIFLGYMISGRLKVF-GFDGAIAIGVRIAAMCLAVSIP 221
Query: 252 LDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVL 311
+D F+GR + FNV+ N S +G P+ +Y L
Sbjct: 222 IDSYFWGRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPR----------CLLTTT 271
Query: 312 WRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTS 371
V R + ++ + YS + HKE+RF+ V+P+ ++AA R
Sbjct: 272 LLVPLGLLVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARM--LI 329
Query: 372 AVVVKMNRLFVLFNIVMIYL 391
R+ + F +++ L
Sbjct: 330 NRHKSFFRMILFFGVILHLL 349
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
Length = 579
Score = 248 bits (628), Expect = 2e-64
Identities = 84/474 (17%), Positives = 151/474 (31%), Gaps = 74/474 (15%)
Query: 3 WWLISLTFIYRLFLCATIRT-VEAPDEWWQSTEVAYNMVFG-KGHLPWEW--RYGLRSVL 58
L + R+ C +T PDE++QS EV + G + PWE+ RSVL
Sbjct: 35 RVLWGGLSLLRVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCRSVL 94
Query: 59 FPAVVALPFYLLKLL--------GRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDEL 110
FP +++ + L L G + +A+ PR+L + +D +V+ + +
Sbjct: 95 FPLLISGSTFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPMGAD 154
Query: 111 LAKRELEL--AEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMA-YCG 167
L + T T+ FS E + LL+ +S+
Sbjct: 155 RWNALALLSGSYVTLVFYTRTFSNTIEGLLFTW------------LLVLVSSHVTWGPTR 202
Query: 168 VRLYGNVIEALLVLLTLQQRRYVPFLLLTGLASAIRVTSAVVL-SPLVFRHLANATREHG 226
+ R + R T PL AT
Sbjct: 203 KEPAPG-----------PRWRSWLLGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATN--P 249
Query: 227 FIRGLFRIVLTGLIVLVAVLGGVMVLDYCFY------GRWVLTPLAFFRFNVLHNLSRFF 280
++ L R L L + D ++ VLTP+ F +N+
Sbjct: 250 GLKSLTREALVLLPGATLTAAVFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARH 309
Query: 281 GEHPWYFYVGPVLVGIVGPHVLF----------------TIAAPLVLWRDTASRAVSRPV 324
G H ++ + G + VL A +L A +S P
Sbjct: 310 GTHARLTHL--AVNGFLLFGVLHAQALQAAWQQLQVGLQASAQMGLLRALGARSLLSSPR 367
Query: 325 LGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLF 384
+L + L S H+E RF+ ++ ++ + + V VLF
Sbjct: 368 SYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCSPQ-TQPVPWKGTV-------VLF 419
Query: 385 NIVMIYLMGYVYRRGPLDVMAEVRDGPRINRLDVIATCYTVPGYSYMHKKVNHL 438
N + L G +++ G + + + + + +++ + HL
Sbjct: 420 NALGALLFGCLHQGGLVPGLEYLEQVVH-APVLPSTPTHYTLLFTHTYMPPRHL 472
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
- fission yeast (Schizosaccharomyces pombe)
emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
[Schizosaccharomyces pombe]
Length = 577
Score = 247 bits (625), Expect = 4e-64
Identities = 68/371 (18%), Positives = 124/371 (33%), Gaps = 46/371 (12%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPA 61
W S+ + RL + R ++ DE + E + +++G G WE+ Y +RS + A
Sbjct: 16 WTFSILAVLRLTSA-SFRVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPEYAIRSWFYIA 74
Query: 62 VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121
+ A+P +L + LG V++ R + A FC + + +A
Sbjct: 75 LHAVPGFLARGLGLSRLH-VFYFIRGVLACFSA------FCETNLILAVARNFNRAVALH 127
Query: 122 TRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVL 181
+ + + +S + + L+LS R V
Sbjct: 128 LTSVLFVNSGMWSASTSF-----LPSSFAMNMVTLALSAQLSPPSTKRTVKVV-----SF 177
Query: 182 LTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIV 241
+T+ SA + P + L + +
Sbjct: 178 ITIGAVIGW-------------PFSAALSIPFILLELVDLKGRFR-----HLFCRWFKAI 219
Query: 242 LVAVL--GGVMVLDYCFYGRWVLTPLAFFRFNVLHN---LSRFFGEHPWYFYVGPVLVGI 296
VA+L G + +D FY R ++NVL +G PW++Y + +
Sbjct: 220 FVALLITGICITVDSLFYHRIQFVAWNIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQH 279
Query: 297 VGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIG---AWTLGFYSLIDHKEMRFVFVVI 353
PLVL + L + + L + + HKE RF++ +
Sbjct: 280 NIVLWFAMACGPLVLLAAFTNWINLDSFLDLSSVISPFYIWLFIFIIQPHKEERFMYPIY 339
Query: 354 PLSLITAAFVL 364
P+ + AA L
Sbjct: 340 PVLCLAAAIGL 350
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
cerevisiae)
emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
Length = 551
Score = 243 bits (616), Expect = 4e-63
Identities = 55/417 (13%), Positives = 113/417 (26%), Gaps = 64/417 (15%)
Query: 3 WWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAV 62
W + T + + I+ E + + ++++
Sbjct: 2 RWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDIL---------------------- 39
Query: 63 VALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEET 122
+ + + D PR V+ + + ++L + +++
Sbjct: 40 ---TYSVFDISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVV 96
Query: 123 RQSKTKGFSYFCEVS------------------VSRSRRGICNSISYTALLLSLSNWYMA 164
R I +S LL + ++++
Sbjct: 97 RGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLM 156
Query: 165 YCGVRLYGNVIEAL------LVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHL 218
+ R N + L L + L + FL SA+ +F +
Sbjct: 157 FYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVI 216
Query: 219 ANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSR 278
LF + G+ L + +D F+ W L + F FNV+ +
Sbjct: 217 FKK-------ISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYAS 269
Query: 279 FFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFY 338
+G P Y L + + T+ A + L L
Sbjct: 270 KWGVEPVTAYFTHYLRMM---FMPPTVLLLNYFGYKLAPAKLKIVSLASLFHII----VL 322
Query: 339 SLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYV 395
S HKE RF+ +P ++ A V K+ + L + + + +
Sbjct: 323 SFQPHKEWRFIIYAVPSIMLLGATGAAHLWEN-MKVKKITNVLCLAILPLSIMTSFF 378
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
Length = 919
Score = 243 bits (615), Expect = 6e-63
Identities = 71/364 (19%), Positives = 126/364 (34%), Gaps = 48/364 (13%)
Query: 1 MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVL 58
+ W+L + Y ++ AT + DE + E + +++ G WE+ + LRS L
Sbjct: 393 LRWFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYL 452
Query: 59 FPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELEL 118
+ L D V++A R+ LV + D + L K +
Sbjct: 453 YILFHELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVV------ALSRKYGKRI 506
Query: 119 AEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEAL 178
A F + + +S S A+ LS + + +V+ +
Sbjct: 507 ATYAVAMLCLTSGCFFASTSF-----LPSSFSMYAISLSSGLLLFEKYAMAVAVSVVGVI 561
Query: 179 LVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTG 238
L S + P+V L F + +T
Sbjct: 562 LGW----------------------PFSILAFLPVVIYSLV-----KRFKQAFIAGAVTT 594
Query: 239 LIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNL-SRFFGEHPWYFYVGPVLVGIV 297
+ + LG +++DY +Y RW + L +NVL S +G FY+
Sbjct: 595 IFL----LGVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNGFNNFN 650
Query: 298 GPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSL 357
+L + + R R +L ++ L F SL HKE RF++ + PL
Sbjct: 651 FCFILAMLFVAIYPVIR---RKYDRALLVVISPMYIWLAFMSLQPHKEERFLYPIYPLIC 707
Query: 358 ITAA 361
++A+
Sbjct: 708 VSAS 711
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
(Swiss Prot accession number P38376)~cDNA EST yk549e12.3
comes from this gene~cDNA EST yk618d6.3 comes from this
gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
yk618d6.5 comes from>
Length = 653
Score = 242 bits (613), Expect = 1e-62
Identities = 66/371 (17%), Positives = 118/371 (31%), Gaps = 58/371 (15%)
Query: 4 WLISLTFIYRLFLCATIR-----TVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRS 56
W S ++++ L I + DE + E + ++G+G WE+ Y +RS
Sbjct: 49 WPFSFGSVFKMLLSIRISGAIWGIINDCDEVYNYWEPLHLFLYGEGFQTWEYSPVYAIRS 108
Query: 57 VLFPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKREL 116
+ + +P L L DT V+ R+ L L + F D + K +
Sbjct: 109 YFYIYLHYIPASLFANLFGDTKIVVFTLIRLTIGLFCLLGEYYAF------DAICKKINI 162
Query: 117 ELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIE 176
F + + +S L + ++
Sbjct: 163 ATGRFFILFSIFSSGMFLASTAF-----VPSSFCMAITFYILGAYLNENWTAGIFCVAFS 217
Query: 177 ALLVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVL 236
++ SAV+ P+V L F +L
Sbjct: 218 TMVGW----------------------PFSAVLGLPIVADMLLLKGLRIRF-------IL 248
Query: 237 TGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHN-LSRFFGEHPWYFYVGPVLVG 295
T L++ + + G ++ D ++G+ VL PL F +NV+ +GE P FY+ +
Sbjct: 249 TSLVIGLCIGGVQVITDSHYFGKTVLAPLNIFLYNVVSGPGPSLYGEEPLSFYIKNLFNN 308
Query: 296 IV--GPHVLFTIAAPLVLWRDTA--------SRAVSRPVLGMLGIGAWTLGFYSLIDHKE 345
F L + P++ + A L + HKE
Sbjct: 309 WNIVIFAAPFGFPLSLAYFTKVWMSQDRNVALYQRFAPIILLAVTTAAWLLIFGSQAHKE 368
Query: 346 MRFVFVVIPLS 356
RF+F + P
Sbjct: 369 ERFLFPIYPFI 379
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
Length = 369
Score = 236 bits (598), Expect = 7e-61
Identities = 52/319 (16%), Positives = 97/319 (30%), Gaps = 18/319 (5%)
Query: 75 RDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSKTKGFSYFC 134
D + PR + I S + +L L T
Sbjct: 5 YDHSQFPGVVPRTFIGPISLAILSSPMSFIFRFWAIPKMWQLLLIRATLGLMNA---MAF 61
Query: 135 EVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLTLQQRRYVPFLL 194
R + L+ + ++ + R N +LV++ ++ +
Sbjct: 62 LYFARSVNRKFGRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVFERLLEGRYES 121
Query: 195 LT--GLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVL 252
AS I +VL + G + G+ + L + +
Sbjct: 122 AVRYATASVILFRCELVLLYGPIFLGYMISGRLKVF-GFDGAIAIGVRIAAMCLAVSIPI 180
Query: 253 DYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLW 312
D F+GR + FNV+ N S +G P+ +Y L
Sbjct: 181 DSYFWGRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPR----------CLLTTTL 230
Query: 313 RDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSA 372
V R + ++ + YS + HKE+RF+ V+P+ ++AA R
Sbjct: 231 LVPLGLLVDRRLPQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARM--LIN 288
Query: 373 VVVKMNRLFVLFNIVMIYL 391
R+ + F +++ L
Sbjct: 289 RHKSFFRMILFFGVILHLL 307
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
Length = 533
Score = 236 bits (597), Expect = 8e-61
Identities = 73/428 (17%), Positives = 144/428 (33%), Gaps = 60/428 (14%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFG-KGHLPWEW--RYGLRSVLFP 60
+ L + F + PDE QS ++ N +FG K LPWE+ + +RSV+
Sbjct: 11 YTFLLILRF-WFSQG--SSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSVVPL 67
Query: 61 AVVALPFYLLKLLGRD---TTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELE 117
V+ LP +LL + + + R+ L+ LID+S++ + A
Sbjct: 68 NVMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLIDLSIWNIVPLNARWSALLLYS 127
Query: 118 LAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEA 177
+ +T F+ E + L+ +++ I
Sbjct: 128 SSFMATTFQTHTFTNSIE-----------------TIFFFLTILFLSKLNSVPLNKKISY 170
Query: 178 LLVLLTLQQRRYVPFLLLTGLASAIRVTSA--VVLSPLVFRHLANATREHGFIRGLFRIV 235
L L +++ L R+T V+ + F + +
Sbjct: 171 LYTFLL---------AIVSVLGFFTRITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLC 221
Query: 236 LTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVG 295
+ + VL ++ DY FYG +V+T ++N G H + +
Sbjct: 222 IFVSVSFATVLA-CILEDYKFYGVFVITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPL 280
Query: 296 IVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPL 355
+ PL+ L +L + SL H+E RF+ +
Sbjct: 281 ---------LCGPLIFVPKLWDVRKPATWLWLL-----PVFILSLFPHQEPRFLLPAASI 326
Query: 356 SLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVRDGPRINR 415
++ + + LFV++ +V+ G +++ G + + EV++
Sbjct: 327 FIVNSG--------CLVRSYWIKFLFVMYAVVLAVFFGIMHQNGVIPAVLEVKNIIEQRN 378
Query: 416 LDVIATCY 423
+ + C
Sbjct: 379 VTTMENCN 386
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
most likely an alpha 1,2 mannosyltransferase utilized
for addition of the fourth, side-branching mannose onto
the GPI core structure.; Smp3p [Saccharomyces
cerevisiae]
sp|Q04174|SMP3_YEAST SMP3 PROTEIN
pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
Length = 516
Score = 234 bits (592), Expect = 3e-60
Identities = 88/465 (18%), Positives = 162/465 (33%), Gaps = 96/465 (20%)
Query: 3 WWLISLTFIYRLFLCATIRTVEAPDEWWQSTEV-AYNMVFGKGHLPWEW--RYGLRSV-L 58
WWL + L LC PDE +Q E+ A + KG +PWE+ ++ RS
Sbjct: 6 WWLYL-VYAIGLMLCLGPS-YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
Query: 59 FPAVVALPFYLLKLL--GRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKREL 116
V F +L+ +D + ++ R+ ++ + C + +L+
Sbjct: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVM------YLLCYHFLIPKLIRDERK 117
Query: 117 ELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIE 176
+ + L L+++ + N IE
Sbjct: 118 AVQFMQKS-------------------------------LLLTSYVTWTYQTHTFSNSIE 146
Query: 177 ALLVLLTLQ-----------QRRYVPFLLLTGLAS----AIRVTS-AVVLSP--LVFRHL 218
L ++ TL QR ++ GL RVT A + P ++F
Sbjct: 147 TLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWKF 206
Query: 219 ANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGR---WVLTPLAFFRFNVLHN 275
+ L+ +++D Y +V+TPL ++N+
Sbjct: 207 YRVHWK---------SFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQ 257
Query: 276 LSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTL 335
+ G HP Y ++ L IVGP +L I + L + + L
Sbjct: 258 NLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLST------------YAIISGL 305
Query: 336 GFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRL---FVLFNIVMIYLM 392
F S H+E+RF+ ++PL + W+ S+ +V ++LFNI+M ++M
Sbjct: 306 LFLSFFQHQELRFLVPLVPLL-----VTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM 360
Query: 393 GYVYRRGPLD-VMAEVRDGPRINRLDVIATCYTVPGYSYMHKKVN 436
G ++ G + + + + Y+ P + YM +
Sbjct: 361 GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLT 405
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
Length = 516
Score = 234 bits (591), Expect = 4e-60
Identities = 88/465 (18%), Positives = 162/465 (33%), Gaps = 96/465 (20%)
Query: 3 WWLISLTFIYRLFLCATIRTVEAPDEWWQSTEV-AYNMVFGKGHLPWEW--RYGLRSV-L 58
WWL + L LC PDE +Q E+ A + KG +PWE+ ++ RS
Sbjct: 6 WWLYL-VYAIGLMLCLGPS-YIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
Query: 59 FPAVVALPFYLLKLL--GRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKREL 116
V F +L+ +D + ++ R+ ++ + C + +L+
Sbjct: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVM------YLLCYHFLIPKLIRDERK 117
Query: 117 ELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIE 176
+ L L+++ + N IE
Sbjct: 118 AVQFI-------------------------------KKSLLLTSYVTWTYQTHTFSNSIE 146
Query: 177 ALLVLLTLQ-----------QRRYVPFLLLTGLAS----AIRVTS-AVVLSP--LVFRHL 218
L ++ TL QRR ++ GL RVT A + P ++F
Sbjct: 147 TLALISTLTVMEDMVNGKNIQRRNFKNSVILGLIFSFGVFNRVTFPAFIFLPCLILFWKF 206
Query: 219 ANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGR---WVLTPLAFFRFNVLHN 275
+ L+ +++D Y +V+TPL ++N+
Sbjct: 207 YRVHWK---------SFSLLLLSFSFSSCLFVLIDTNIYNNGKGFVITPLNNLKYNLNVQ 257
Query: 276 LSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTL 335
+ G HP Y ++ L I+GP +L I + L + + L
Sbjct: 258 NLQVHGLHPRYTHLLVNLPQILGPVLLLAIFSGYKLDKLST------------YAIISGL 305
Query: 336 GFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRL---FVLFNIVMIYLM 392
F S H+E+RF+ ++PL + W+ S+ +V ++LFNI+M ++M
Sbjct: 306 LFLSFFQHQELRFLVPLVPLL-----VTNLNWTPLSSTLVNKKIFKGTWLLFNIIMAFIM 360
Query: 393 GYVYRRGPLD-VMAEVRDGPRINRLDVIATCYTVPGYSYMHKKVN 436
G ++ G + + + + Y+ P + YM +
Sbjct: 361 GISHQAGIIQFLGDYFHFRTEQMGVHIWWKTYSPPTWMYMSNNLT 405
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
lipid-linked oligosaccharides; Alg9p [Saccharomyces
cerevisiae]
sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
cerevisiae)
emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
Length = 555
Score = 230 bits (582), Expect = 5e-59
Identities = 70/392 (17%), Positives = 131/392 (32%), Gaps = 53/392 (13%)
Query: 5 LISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAV 62
L+ L F+ R+++ T + DE + E +V G G WE+ Y +RS F
Sbjct: 10 LLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYSIRSWAFLLP 69
Query: 63 V-ALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121
+ + + K ++ W +F R +++ + A L
Sbjct: 70 FYCILYPVNKFTDLESHWN-FFITRACLGFFSFIMEFKLHREIAGSLAL----------- 117
Query: 122 TRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVL 181
+ F F S + ++++ L + + + Y N
Sbjct: 118 QIANIWIIFQLFNPGWFHASVELLPSAVAM-LLYVGATRHSLRYLSTGSTSN-------- 168
Query: 182 LTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIV 241
+ L LAS + ++LS + H R IR F L +
Sbjct: 169 -------FTKSLAYNFLASILGWPFVLILSLPLCLHYLFNHRIISTIRTAFDCCL----I 217
Query: 242 LVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVL----HNLSRFFGEHPWYFYVGPVLVGIV 297
V+V D FYG+ +NV+ + FG PWY+Y +L+
Sbjct: 218 FSLTAFAVIVTDSIFYGKLAPVSWNILFYNVINASEESGPNIFGVEPWYYYPLNLLLNFP 277
Query: 298 GPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSL 357
P ++ I L + + + ++ HKE RF++ + L
Sbjct: 278 LPVLVLAILGIFHL-----------RLWPLWASLFTWIAVFTQQPHKEERFLYPIYGLIT 326
Query: 358 ITAAFVL---VRWSRTSAVVVKMNRLFVLFNI 386
++A+ + ++ K +L VL +
Sbjct: 327 LSASIAFYKVLNLFNRKPILKKGIKLSVLLIV 358
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
Length = 570
Score = 228 bits (578), Expect = 1e-58
Identities = 70/364 (19%), Positives = 126/364 (34%), Gaps = 48/364 (13%)
Query: 1 MPWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVL 58
+ W+L + Y ++ AT + DE + E + +++ G WE+ + LRS L
Sbjct: 44 LRWFLPFIALCYLRYMSATSNIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYL 103
Query: 59 FPAVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELEL 118
+ L D V++A R+ LV + D + L K +
Sbjct: 104 YILFHELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVV------ALSRKYGKRI 157
Query: 119 AEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEAL 178
A F + + +S S A+ LS + + +V+ +
Sbjct: 158 ATYAVAMLCLTSGCFFASTSF-----LPSSFSMYAISLSSGLLLFEKYAMAVAVSVVGVI 212
Query: 179 LVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTG 238
L S + P+V L + + G
Sbjct: 213 LGW----------------------PFSILAFLPVVIYSLVKR---------FKQAFIAG 241
Query: 239 LIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNL-SRFFGEHPWYFYVGPVLVGIV 297
+ + +LG +++DY +Y RW + L +NVL S +G FY+
Sbjct: 242 AVTTIFLLGVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFYIRNGFNNFN 301
Query: 298 GPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSL 357
+L + + R R +L ++ L F SL HKE RF++ + PL
Sbjct: 302 FCFILAMLFVAIYPVIR---RKYDRALLVVISPMYIWLAFMSLQPHKEERFLYPIYPLIC 358
Query: 358 ITAA 361
++A+
Sbjct: 359 VSAS 362
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
(Schizosaccharomyces pombe)
emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
architecture [Schizosaccharomyces pombe]
Length = 547
Score = 225 bits (569), Expect = 2e-57
Identities = 68/391 (17%), Positives = 132/391 (33%), Gaps = 58/391 (14%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
W ++ + + +T E + + +++ + W
Sbjct: 9 WYLANILLVTCIGYYSYKTPFTKVEESFAMQAIHDI------QTYRWD------------ 50
Query: 64 ALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETR 123
+ L F P + A++ + V + A
Sbjct: 51 --LSKVYDHLEFPGAVKRSFIPSLFIAVLSYIPSWFVNPLLA---------------ARW 93
Query: 124 QSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLV--- 180
+ VS S S+R S + +L S + +++ Y R N+ +
Sbjct: 94 TIGYLSWESMNSVSCSISKRFGTLSGAL-FILFSCAQFHLVYYMSRPLSNIFGLIATNHS 152
Query: 181 -LLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGL 239
L L+ Y +L A+ +R A++L L+ L L +++L G+
Sbjct: 153 LSLLLKNNYYGSISILVFAAAIVRSEIALLLMCLILPLLLQRR------ITLSKLLLVGI 206
Query: 240 IVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGP 299
+A +G ++D F+G W L F FNV+ S +G P+Y+Y + + P
Sbjct: 207 SSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFYYYFVRLPWLFLNP 266
Query: 300 HVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLIT 359
L + S +P ++ + + + YS + HKE RF+ IP
Sbjct: 267 TTLLFL---------LISFVYIKPARLLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAA 317
Query: 360 AAFVLV---RWSRTSAVVVKMNRLFVLFNIV 387
+A S+ + ++ RL I+
Sbjct: 318 SAIGASLCFNASKFGKKIFEILRLMFFSGII 348
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
chromosome I precursor [Leishmania major]
Length = 822
Score = 201 bits (507), Expect = 3e-50
Identities = 61/327 (18%), Positives = 105/327 (31%), Gaps = 35/327 (10%)
Query: 5 LISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEW--RYGLRSVLFPAV 62
+ L+ + + DE + E + +++G G WE R+ LRS LF +
Sbjct: 15 FLLLSLTHYFASSFLP--ISDCDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSWLFLWI 72
Query: 63 VALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDE--------LLAKR 114
A P L++ ++ V+F R+L L ++ C LL
Sbjct: 73 HAWPVVLIRGAASLSSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLLA 132
Query: 115 ELELAEETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNV 174
+ F+ C V S + S +ALL + +
Sbjct: 133 NYPIQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLSRVGDRPTQNTMPAAAAGT 192
Query: 175 IEALLVLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSP---LVFRHLANATRE-----HG 226
A L ++ P L + + + L F LA T
Sbjct: 193 --AQLSMMVPPSPSSAPTLHSSSASPPSAPPRHLCWFIGAALCFSVLAVVTGWPFAALIS 250
Query: 227 FIRGLFRIVLTGLIVLVAVLG-------GVMVLDYCFYGRWVLTPLAFFRFNVLHN---L 276
+ GL ++ + L LG V V D +Y RW L+ +N
Sbjct: 251 ALVGLDLLLRFPVRTLACTLGSLLVACAAVFVADVRYYCRWTLSSWNVVMYNGFGGSGRG 310
Query: 277 SRFFGEHPWYFYVGPVLVGIVGPHVLF 303
FG P +F+ + ++ H++F
Sbjct: 311 PELFGVEPIFFFWKNL---MLNFHLMF 334
Score = 41.2 bits (96), Expect = 0.046
Identities = 12/42 (28%), Positives = 16/42 (37%)
Query: 323 PVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVL 364
L + F+ I HKE RF+ P L+ A L
Sbjct: 434 RELLHIMPFFVWFLFWMSIAHKEERFMSPAYPFMLLAATRTL 475
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
Length = 278
Score = 184 bits (463), Expect = 4e-45
Identities = 40/238 (16%), Positives = 86/238 (35%), Gaps = 27/238 (11%)
Query: 292 VLVGIVGPHVLFTIAAPLVLW-RDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVF 350
L ++G + + + + P + L YS + HKE RF+F
Sbjct: 1 ALPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIF 60
Query: 351 VVIPLSLITAAFVLVRW----SRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAE 406
+ PL ++ ++F L+R + + + + L ++ + L+ + G ++VM
Sbjct: 61 PLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVMKF 120
Query: 407 VRDGPRINRLDVIATCYTVPGYSYMHK-KVNHLGFVDCSIDLD---EKTGLPKV----TE 458
+ + P I+ L I C++ PG SY+H+ + L + C+ L + K+ E
Sbjct: 121 LHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCNPPLHLLGDPEAYSKLETYMDE 180
Query: 459 DIMFRRYPKEYVLWRYDG--------------KHSFNMSDLEESRKASELQSVVMPKS 502
++ + + E + + L+ + S
Sbjct: 181 SDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENAFLKDFLKDSS 238
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
Length = 509
Score = 180 bits (453), Expect = 6e-44
Identities = 67/364 (18%), Positives = 115/364 (31%), Gaps = 66/364 (18%)
Query: 7 SLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVVALP 66
L R+ PDE +Q E A+ + FG +PWE+RYG+R L P ++A
Sbjct: 28 LLALCLRMTAIF-PIGYYHPDEIFQYLEQAHRLAFGYSVIPWEYRYGMRGGLVPVLLAAA 86
Query: 67 FYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVF---CMGATLDELLAKRELELAEETR 123
+ + ++ W P + AL+ + S + + + LA E
Sbjct: 87 MK-MGDIMNTQSFLYWVLPHAITALLSLGVIWSAYKLGRLHSFFTGCLAMFVAATWYEIV 145
Query: 124 QSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVLLT 183
S + + L LS + M L
Sbjct: 146 LFAAHPLSESLSFAAFMPAAYYLIAEEKKKSSLILSGFLM----------------GLSA 189
Query: 184 LQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLV 243
L + +Y+P +L +F N + +L GL +
Sbjct: 190 LLRFQYIPS----------------ILFITLFTLRINVRQW-------GYFILGGLGAVF 226
Query: 244 AVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNL----SRFFGEHPWYFYVGPVLVGIVGP 299
+ + PL + N+ NL + +G P Y Y +
Sbjct: 227 ISSLSDIFIGEY--------PLLWLFKNIQQNLIFHRAEDYGTAPIYSYFFDIWTNWKW- 277
Query: 300 HVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFVFVVIPLSLIT 359
F++ P+ + + G L F+ L+ HKE RF+F+ + +I
Sbjct: 278 ---FSLILPIPILVAAYRYPA------LFGTALVNLIFHMLVSHKEYRFIFLSSGIFIIL 328
Query: 360 AAFV 363
AA
Sbjct: 329 AAIG 332
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
Length = 457
Score = 177 bits (446), Expect = 4e-43
Identities = 54/330 (16%), Positives = 98/330 (29%), Gaps = 55/330 (16%)
Query: 151 YTALLLSLSNWYMAYCGVRLYGNVIEALL-VLLTL------------------QQRRYVP 191
+ AL L ++ R + N IE LL L + + R
Sbjct: 34 WNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWL 93
Query: 192 FLLLTGLASAIRVTSAVVL-SPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVM 250
+ R T PL AT ++ L R L L +
Sbjct: 94 LGGIVAAGFFNRPTFLAFAVVPLYLWGTRGATN--PGLKSLTREALVLLPGATLTAAVFV 151
Query: 251 VLDYCFY------GRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFT 304
D ++ VLTP+ F +N+ G H ++ + G + VL
Sbjct: 152 ATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHL--AVNGFLLFGVLHA 209
Query: 305 IAA----------------PLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRF 348
A +L A +S P +L + L S H+E RF
Sbjct: 210 QALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEARF 269
Query: 349 VFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIVMIYLMGYVYRRGPLDVMAEVR 408
+ ++ ++ + + V LFN + L G +++ G + + +
Sbjct: 270 LIPLLVPLVLLCSPQ-TQPVPWKGTV-------ALFNALGALLFGCLHQGGLVPGLEYLE 321
Query: 409 DGPRINRLDVIATCYTVPGYSYMHKKVNHL 438
+ + +++ + HL
Sbjct: 322 QVVH-APVLPSTPTHYTLLFTHTYMPPRHL 350
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
Length = 198
Score = 139 bits (348), Expect = 1e-31
Identities = 27/137 (19%), Positives = 45/137 (32%), Gaps = 9/137 (6%)
Query: 9 TFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWR--YGLRSVLFPAVVALP 66
RL + DE + E + +++G+G WE+ Y +RS + + A P
Sbjct: 65 LLSARLCAALL-SNISDCDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWP 123
Query: 67 FYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEETRQSK 126
+ + V++ R L A V C + K L ++
Sbjct: 124 AAFHARILQTNKILVFYFLRCLLAFVS------CICELYFYKAVCKKFGLHVSRMMLAFL 177
Query: 127 TKGFSYFCEVSVSRSRR 143
FC SV S
Sbjct: 178 VLSTGMFCSSSVYPSPL 194
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
Length = 197
Score = 131 bits (329), Expect = 2e-29
Identities = 46/205 (22%), Positives = 84/205 (40%), Gaps = 19/205 (9%)
Query: 153 ALLLSLSNWYMAYCGVRLYGNVIEALLV----LLTLQQRRYVPFLLLTGLASAIRVTSAV 208
+L S + +++ Y R N+ + L L+ Y +L A+ +R A+
Sbjct: 8 FILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSLLLKNNYYGSISILVFAAAIVRSEIAL 67
Query: 209 VLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFF 268
+L L+ L L +++L G+ +A +G ++D F+G W L F
Sbjct: 68 LLMCLILPLLLQRR------ITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWPELEAF 121
Query: 269 RFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGML 328
FNV+ S +G P+Y+Y + + P L + S +P ++
Sbjct: 122 LFNVVEGKSSDWGTSPFYYYFVRLPWLFLNPTTLLFL---------LISFVYIKPARLLI 172
Query: 329 GIGAWTLGFYSLIDHKEMRFVFVVI 353
+ + + YS + HKE RF+ I
Sbjct: 173 YVPLFFIFVYSFLGHKEWRFIIYSI 197
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
Length = 283
Score = 129 bits (323), Expect = 1e-28
Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 10/131 (7%)
Query: 268 FRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGM 327
FNV+ S FG HPWY+Y+ + ++ ++ I L + RP L
Sbjct: 129 IAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGP-------NIFRPSLLP 181
Query: 328 LGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIV 387
+ +SL+ HKE RF+ +IPL I A + + + NI
Sbjct: 182 FFATITYIIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRG---SAMAVMIAINIG 238
Query: 388 MIYLMGYVYRR 398
+ +++
Sbjct: 239 IALFTSRYHQK 249
Score = 92.6 bits (228), Expect = 2e-17
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
L++ ++R + + PDE +QS EVA+++V+G GHL WEWR+ LRS PA++
Sbjct: 70 RLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPALI 129
Query: 64 ALPFYLLKL-LGRDTTWAVWFAPRVLQALV 92
A L W W+ + A++
Sbjct: 130 AFNVVQGGSALFGVHPW-YWYIVSGIPAVL 158
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
[Caenorhabditis elegans]
Length = 232
Score = 123 bits (308), Expect = 7e-27
Identities = 30/131 (22%), Positives = 51/131 (38%), Gaps = 10/131 (7%)
Query: 268 FRFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGM 327
FNV+ S FG HPWY+Y+ + ++ ++ I L + RP L
Sbjct: 65 IAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGP-------NIFRPSLLP 117
Query: 328 LGIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLFNIV 387
+ +SL+ HKE RF+ +IPL I A + + + NI
Sbjct: 118 FFATITYIIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRG---SAMAVMIAINIG 174
Query: 388 MIYLMGYVYRR 398
+ +++
Sbjct: 175 IALFTSRYHQK 185
Score = 88.3 bits (217), Expect = 3e-16
Identities = 29/90 (32%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Query: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
L++ ++R + + PDE +QS EVA+++V+G GHL WEWR+ LRS PA++
Sbjct: 6 RLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPALI 65
Query: 64 ALPFYLLKL-LGRDTTWAVWFAPRVLQALV 92
A L W W+ + A++
Sbjct: 66 AFNVVQGGSALFGVHPW-YWYIVSGIPAVL 94
>ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
pir||S75173 hypothetical protein sll1946 - Synechocystis sp. (strain PCC 6803)
dbj|BAA17087.1| (D90903) ORF_ID:sll1946~unknown protein [Synechocystis sp. PCC
6803]
Length = 825
Score = 99.2 bits (245), Expect = 2e-19
Identities = 23/117 (19%), Positives = 43/117 (36%), Gaps = 12/117 (10%)
Query: 285 WYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFY------ 338
W +Y + + ++ + ++ + ++ P G LG+Y
Sbjct: 272 WTYYWQDLPNALSWVWLIPPLVGVILSLLNRFPASLQIPSWREAKPGLLWLGYYYGGTYL 331
Query: 339 --SLIDHKEMRFVFVVIPLSLITAAFVLVRWSRTSAVVVK----MNRLFVLFNIVMI 389
S I +K+ R++ +P+ I AF L RW V + L L N+ I
Sbjct: 332 ICSAIQNKDDRYILPYLPIVAIFLAFGLTRWCGRWLWVRWGTLAITILITLGNLFPI 388
>ref|NP_069450.1| (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
pir||H69326 conserved hypothetical protein AF0616 - Archaeoglobus fulgidus
gb|AAB90624.1| (AE001062) conserved hypothetical protein [Archaeoglobus fulgidus]
Length = 533
Score = 40.8 bits (95), Expect = 0.061
Identities = 42/399 (10%), Positives = 112/399 (27%), Gaps = 43/399 (10%)
Query: 6 ISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHL----PWEWRYGLR-SVLFP 60
+ + F+ T A D+ QS + A ++ + + ++ ++ S +P
Sbjct: 11 FLVLLLITTFVVITNVYFIAWDDSPQSWDPALHLTYSFVYFNLIKSLQFSEIVKVSNYYP 70
Query: 61 AVVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCM-GATLDELLAKRELELA 119
L L L + A++ LI + + +++ R +
Sbjct: 71 PFFYLSSTPLYFLFGFSED---------IAILTNLIYYFILIYSVFQIAKIMKDRNAGVI 121
Query: 120 EETRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALL 179
S F V + + + L L ++ + +
Sbjct: 122 SAVIISAFPALIKFQRVYMIDFALLSLTAFAI-LLYLRSEDFRNLKY-----SVLFGIVF 175
Query: 180 VLLTLQQRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREH--GFIRGLFRIVLT 237
+ L + +++ + A + + + + L
Sbjct: 176 GIAELTKWNAFVYIIPSIFALFLVNYFMRC---PYCHQIVKNGWKVGYRRFCSKKHLKLY 232
Query: 238 --------GLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNL----SRFFGEHPW 285
++ L + +Y + T + + F W
Sbjct: 233 EKSAKTNNTMLNFAISLFVAFLFAAWWYLPNLSTVIMRLTYFANIGGKEGDPAFLTIQGW 292
Query: 286 YFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKE 345
+Y +L + ++ + L+++ LG+L A +L+ +K+
Sbjct: 293 IYYANSILDAVGAVFLILFAVSIYYLYKNNRYL-----FLGLLTPIALIYIILTLLSNKD 347
Query: 346 MRFVFVVIPLSLITAAFVLVRWSRTSAVVVKMNRLFVLF 384
R++ V+P I+ + + + + +
Sbjct: 348 PRYIMPVLPFVAISIGVFVSSLANRKYSTILTFIILLFG 386
CPU time: 164.14 user secs. 2.82 sys. secs 166.96 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.317 0.169 0.469
Gapped
Lambda K H
0.270 0.0593 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 358534380
Number of Sequences: 887402
Number of extensions: 18670395
Number of successful extensions: 93758
Number of sequences better than 10.0: 1176
Number of HSP's better than 10.0 without gapping: 55
Number of HSP's successfully gapped in prelim test: 1150
Number of HSP's that attempted gapping in prelim test: 92163
Number of HSP's gapped (non-prelim): 2098
length of query: 558
length of database: 277,845,442
effective HSP length: 51
effective length of query: 507
effective length of database: 232,587,940
effective search space: 117922085580
effective search space used: 117922085580
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.9 bits)
S2: 76 (33.7 bits)