Sequences with E-value BETTER than threshold (0.002)
ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 701 0.0
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 619 e-176
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 541 e-152
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 526 e-148
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 523 e-147
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 475 e-133
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 446 e-124
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 417 e-115
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 398 e-109
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 396 e-109
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 394 e-108
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 393 e-108
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 385 e-106
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 351 2e-95
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 343 3e-93
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 323 7e-87
gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan ... 309 7e-83
gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melano... 287 3e-76
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 274 2e-72
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 262 1e-68
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 259 1e-67
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 251 2e-65
emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus mus... 249 9e-65
ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo ... 247 2e-64
emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-... 247 4e-64
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 239 7e-62
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 237 5e-61
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 232 1e-59
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 226 6e-58
ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans] ... 216 8e-55
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 215 1e-54
pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans 210 7e-53
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 209 7e-53
pir||T39659 cell wall biosynthesis protein N3265 homolog - fissi... 202 1e-50
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 168 3e-40
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 167 4e-40
ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Sacch... 161 2e-38
gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 138 3e-31
dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharom... 135 2e-30
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 121 3e-26
pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans 117 6e-25
gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protei... 115 1e-24
ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]... 111 3e-23
Sequences with E-value WORSE than threshold
ref|NP_276829.1| (NC_000916) unknown [Methanothermobacter therma... 43 0.009
ref|NP_485359.1| (NC_003272) unknown protein [Nostoc sp. PCC 712... 40 0.12
Alignments
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase -like protein [Arabidopsis
thaliana]
gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
Length = 548
Score = 701 bits (1792), Expect = 0.0
Identities = 548/548 (100%), Positives = 548/548 (100%)
Query: 1 MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF
Sbjct: 1 MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
Query: 61 NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA
Sbjct: 61 NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI
Sbjct: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII
Sbjct: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV
Sbjct: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
Query: 301 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 360
MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ
Sbjct: 301 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 360
Query: 361 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 420
MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM
Sbjct: 361 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 420
Query: 421 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 480
NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP
Sbjct: 421 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 480
Query: 481 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVV 540
LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVV
Sbjct: 481 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVV 540
Query: 541 YVVNHAFP 548
YVVNHAFP
Sbjct: 541 YVVNHAFP 548
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein - Arabidopsis
thaliana
emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein [Arabidopsis
thaliana]
Length = 498
Score = 619 bits (1580), Expect = e-176
Identities = 496/519 (95%), Positives = 496/519 (95%), Gaps = 23/519 (4%)
Query: 1 MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF
Sbjct: 1 MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
Query: 61 NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA
Sbjct: 61 NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
PRLMQSIFSAIGDLYLYKLSDALYGGNVATWS TVLTI
Sbjct: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWS-----------------------TVLTI 157
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII
Sbjct: 158 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 217
Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV
Sbjct: 218 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 277
Query: 301 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 360
MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ
Sbjct: 278 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 337
Query: 361 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 420
MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM
Sbjct: 338 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 397
Query: 421 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 480
NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP
Sbjct: 398 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 457
Query: 481 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKE 519
LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKE
Sbjct: 458 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKE 496
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
GPI-anchor biosynthesis [Mus musculus]
dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
Length = 542
Score = 541 bits (1381), Expect = e-152
Identities = 201/548 (36%), Positives = 308/548 (55%), Gaps = 47/548 (8%)
Query: 1 MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
M +R+RK V+ ++ G +G + LF +A R++N L+QT F
Sbjct: 22 MKLRRRK----------SRQYVSAQEKRSPRRGLLGENTYLVLFTIALRILNCFLVQTSF 71
Query: 61 NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
PDE+WQSLEVAHR +F YGY+TWEW +R Y +P++FA +YK+L + G D+ +I
Sbjct: 72 VPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLHLLGKDSVQFLIWI 131
Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
PRL Q++ SA+ D+ LY L L VA W CQ+ +WF ++C RT +N +ET LT
Sbjct: 132 PRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTA 191
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
+ L+Y+P S++ + K+ L++A LAC +RPT+ + W+ + + K+ +
Sbjct: 192 LALFYYPLEGSRSVN---SIKYSLLVA-LACVVRPTALIPWVPLLFRHFYQEQRKLHLTL 247
Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
+P+G + + ++DR+ +G W +V LNFLKFN L + G +YG+HPWHWY +QGF V
Sbjct: 248 HHFLPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPV 307
Query: 301 MLFTFTPFSIAG--IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
+L T PF I G + + L +LW L +YS+LGHKEFRF+ PVLP ++F GY+
Sbjct: 308 VLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSL 367
Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
A ++ W + ++ FLL +N+P+A Y L HQRGT D
Sbjct: 368 AHLKT----------------------WR---KAALSFLLLSNVPLAFYTGLVHQRGTLD 402
Query: 419 AMNYLSDEAYKGRV---KSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDES 473
MN++ +G S+ +MPCHSTPYYS +H + M+FL C P + + LDE+
Sbjct: 403 VMNHIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEA 462
Query: 474 DQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRD 533
D F +NPL + + + + P+H+V F E ++ F+ +++ FFH H+ R
Sbjct: 463 DMFYLNPLRWLQQEFHSNASLPTHLVTFNVLEKEINTFLTSGNYERAATFFHTHWPE-RR 521
Query: 534 LQSSVVVY 541
S + VY
Sbjct: 522 TGSHIHVY 529
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
Length = 554
Score = 526 bits (1342), Expect = e-148
Identities = 205/548 (37%), Positives = 310/548 (56%), Gaps = 48/548 (8%)
Query: 2 DIRKRKNAGGDGDGGADGASVNVGDEPDSFGG-RIGSPRRIFLFCLAFRVVNALLIQTYF 60
+RKRK N ++ G +G + LF LA R++N L+QT F
Sbjct: 33 KLRKRK----------STLYFNTQEKSARRRGDLLGENIYLLLFTLALRILNCFLVQTSF 82
Query: 61 NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
PDE+WQSLEV+H +F YGY+TWEW +RSY +P++FA +YK+L + G D+ ++I
Sbjct: 83 VPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWI 142
Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
PRL Q++ SA+ D+ LY L L VA W FCQ+ +WF ++C RT +N +ETVLTI
Sbjct: 143 PRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTI 202
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
+ L+Y+P S++ + K+ ++A LA IRPT+ ++W + P K+ I+
Sbjct: 203 IALFYYPLEGSKSMN---SVKYSSLVA-LAFIIRPTAVILWTPLLFRHFCQEPRKLDLIL 258
Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
+P+G + L + ++DR+ +G W +V NFLKFN L + G +YG+HPWHWYF+QGF V
Sbjct: 259 HHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPV 318
Query: 301 MLFTFTPFSIAG--IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
+L T PF I G + + + L +LW L +YS+L HKEFRF+ PVLP ++F GY+
Sbjct: 319 ILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSL 378
Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
++ + ++ FL +N+ +ALY L HQRGT D
Sbjct: 379 THLK-------------------------TWKKPALSFLFLSNLFLALYTGLVHQRGTLD 413
Query: 419 AMNYLSDEAYKGRVK---SILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDES 473
M+++ Y K SI +MPCHSTPYYS +H +PM+FL C P + + LDE+
Sbjct: 414 VMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEA 473
Query: 474 DQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRD 533
D F +NPL ++ + + P+H++ F+ E ++ F+I ++K FFH H R
Sbjct: 474 DVFYLNPLNWSHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGR- 532
Query: 534 LQSSVVVY 541
+ S + VY
Sbjct: 533 IGSHIYVY 540
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
(EC 2.4.1.130) PIGB - human
dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
Length = 554
Score = 523 bits (1335), Expect = e-147
Identities = 204/548 (37%), Positives = 309/548 (56%), Gaps = 48/548 (8%)
Query: 2 DIRKRKNAGGDGDGGADGASVNVGDEPDSFGG-RIGSPRRIFLFCLAFRVVNALLIQTYF 60
+RKRK N ++ G +G + LF +A R++N L+QT F
Sbjct: 33 KLRKRK----------STLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSF 82
Query: 61 NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
PDE+WQSLEV+H +F YGY+TWEW +RSY +P++FA +YK+L + G D+ ++I
Sbjct: 83 VPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWI 142
Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
PRL Q++ SA+ D+ LY L L VA W FCQ+ +WF ++C RT +N +ETVLTI
Sbjct: 143 PRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTI 202
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
+ L+Y+P S++ + K+ ++A LA IRPT+ ++W + P K+ I+
Sbjct: 203 IALFYYPLEGSKSMN---SVKYSSLVA-LAFIIRPTAVILWTPLLFRHFCQEPRKLDLIL 258
Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
+P+G + L + ++DR+ +G W +V NFLKFN L + G +YG+HPWHWYF+QGF V
Sbjct: 259 HHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPV 318
Query: 301 MLFTFTPFSIAG--IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
+L T PF I G + + + L +LW L +YS+L HKEFRF+ PVLP ++F GY+
Sbjct: 319 ILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSL 378
Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
++ + ++ FL +N+ +ALY L HQRGT D
Sbjct: 379 THLK-------------------------TWKKPALSFLFLSNLFLALYTGLVHQRGTLD 413
Query: 419 AMNYLSDEAYKGRVK---SILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDES 473
M+++ Y K SI +MPCHSTPYYS +H +PM+FL C P + + LDE+
Sbjct: 414 VMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEA 473
Query: 474 DQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRD 533
D F +NPL + + + P+H++ F+ E ++ F+I ++K FFH H R
Sbjct: 474 DVFYLNPLNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGR- 532
Query: 534 LQSSVVVY 541
+ S + VY
Sbjct: 533 IGSHIYVY 540
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
Length = 506
Score = 475 bits (1211), Expect = e-133
Identities = 289/544 (53%), Positives = 365/544 (66%), Gaps = 63/544 (11%)
Query: 1 MDIRKRKNAG-----GDGDGGADGASVNVGDEPD--SFGGRIGSPRRIFLFCLAFRVVNA 53
M R+R+NA G + + + G+E + +GS RR+ LAFR NA
Sbjct: 1 MSHRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANA 60
Query: 54 LLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDT 113
LL++TYFNPDEHWQ LEVAHR +FGYG++TWEWKRG+RSYLHP +FA LYK+L + LD+
Sbjct: 61 LLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDS 120
Query: 114 PYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNC 173
P+ M APRL+QS+F++ GDLYLYKLS ++ +VA
Sbjct: 121 PWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAH----------------------- 157
Query: 174 LETVLTIMGLYYWPCIRDS-------------SIDYPVNRKWGLVIAALACAIRPTSAVI 220
+ETVLT+ GLYYW +S S P +RK L+IAALACAIRPTSA+
Sbjct: 158 METVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAIT 217
Query: 221 WLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSS 280
WLYVG+L+ +K +FI LEV+P+G VL T LD MYGS +IVPLNFLKFN SS
Sbjct: 218 WLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSS 277
Query: 281 GGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEF 340
GGDYYGTH +HWYF+QGF M++TF PFSI+GI+KS+ +L+ LI+WVL +YSILGHKEF
Sbjct: 278 GGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEF 337
Query: 341 RFVLPVLPIALIFSGY---AFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFL 397
RFVLPVLP +FSG+ A AQ++ G + +L+LSV L
Sbjct: 338 RFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKG---------------RLSRLKLSVILL 382
Query: 398 LATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQ 457
+ TN+PMALYMSL+HQRGTEDAM YLS EA+ GRVKS+LFLMPCHSTPYYSTLH N+PM+
Sbjct: 383 ILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLPMR 442
Query: 458 FLDCTPSAEKGELDESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSF 517
FLDCTPS KG LDESD+FL+NP F E+ N S SHIVLF SEE ++ ++++SF
Sbjct: 443 FLDCTPSENKGTLDESDRFLMNPADFVGEVFGNLSS-FSHIVLFESEERHVK-LLLRNSF 500
Query: 518 KEVR 521
+EV+
Sbjct: 501 QEVK 504
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
Length = 512
Score = 446 bits (1136), Expect = e-124
Identities = 176/518 (33%), Positives = 273/518 (51%), Gaps = 73/518 (14%)
Query: 40 RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLF 99
+FL LA R+ + ++QTY+ PDE+WQSLEVAH+ FGYGY+TWEW +GIRSY++P+L
Sbjct: 5 YVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLI 64
Query: 100 AFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMAN 159
A LYK+L + LD+ ++++ PR + W+LF +
Sbjct: 65 AGLYKILALLQLDSAHLLVVLPR-------------------------IRKWALFLILVP 99
Query: 160 WFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAV 219
WF F+ +RT +N LE LT + L Y+P +S+ L AA+ C +RPT+AV
Sbjct: 100 WFWFYTGSRTLANTLEASLTTIALSYFPWYGESTA--------YLWPAAICCFLRPTAAV 151
Query: 220 IWLYVGMLELFL-TPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL 278
IWL + + L N ++ I+ + IG LV G +D +G ++ P FLK+N
Sbjct: 152 IWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIF 211
Query: 279 SSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIK--------SKNQKLSALILWVLA 330
++ G +YG+HPWHWYF+ G +L T I G+++ +++L I L
Sbjct: 212 NNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLV 271
Query: 331 IYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKL 390
+ S + HKEFRFV P+LP+ L A ++ + SS+ W+ L
Sbjct: 272 VLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASST---------------MLWTTAL 316
Query: 391 RLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVK-----SILFLMPCHSTP 445
+L N+ A Y+S HQ+G + M L + A + R + +ILFLMPCHSTP
Sbjct: 317 -----VILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTP 371
Query: 446 YYSTLHRNIPMQFLDCTPSAEKGEL--DESDQFLVNPLGFASEL--ARNWSEPPSHIVLF 501
YYS +H+N+ M+FL C P+ EK E DE+D+F +P+ + + + P+H+VLF
Sbjct: 372 YYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLF 431
Query: 502 ASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVV 539
+ F+ +++ + R HA + R +S +V
Sbjct: 432 DPLAENISVFL--RNYRLLHRIEHAENRQSRTGRSILV 467
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
(Schizosaccharomyces pombe)
emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
[Schizosaccharomyces pombe]
Length = 506
Score = 417 bits (1063), Expect = e-115
Identities = 164/536 (30%), Positives = 260/536 (47%), Gaps = 70/536 (13%)
Query: 40 RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLF 99
+L L FR NAL ++T+F PDE +QSLEVAH IF YG++TWEW IRS LHP++F
Sbjct: 4 WFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHPLIF 63
Query: 100 AFLYKLLQVTGLDTPYIMIK-APRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMA 158
A LY++LQV LD+ Y + AP+L+Q F+AI D YK + YG A W+L C +
Sbjct: 64 AALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKTANWTLACSLV 123
Query: 159 NWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWG-------LVIAALAC 211
+ + RTFSN LET LT +G YY+ P RK + +AA AC
Sbjct: 124 SIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAFAC 183
Query: 212 AIRPTSAVIWLYVGMLE-------------LFLTPNKVKFI-------ILEVIPIGSLVL 251
IRPT+ ++W++ + N+ +F+ + + + +
Sbjct: 184 FIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVSLF 243
Query: 252 GFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIA 311
+ DR++YG +V ++F +FN S YG + WH+Y +Q ++ F PF
Sbjct: 244 LVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPF--- 300
Query: 312 GIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSS 371
++ + + + + IL V YS++GHKE RFV P+ PI L +G F SS
Sbjct: 301 -VLLTMDLQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFF-----------SS 348
Query: 372 VTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMAL-YMSLFHQRGTEDAMNYLSDEAYKG 430
+ K+ R +FL+ + + ++ FHQ G + M + A K
Sbjct: 349 FSSWKRAAR-------------FFFLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKN 395
Query: 431 RVKSILFLMPCHSTPYYSTLHRNIP---MQFLDCTPSAEKGELDESDQFLVNPLGFASEL 487
+ L L PCH+TP+ S +H +FL C P + DE+D+F N F ++
Sbjct: 396 QTG--LILAPCHTTPWQSHIHSPFAENGWKFLTCEPFEKP--FDETDRFYENMPTFLDKI 451
Query: 488 ARNWSEPPSHIVLFASEETKLRDFMIQHS--FKEVRRFFHAHFKVDRDLQSSVVVY 541
E P +++ F L ++ ++EV+R++++ R+ +++VY
Sbjct: 452 ----KEWPDYLIFFEERFYSLYSYLDSRGLKYEEVQRYYNSLIPESRERAGALLVY 503
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
Length = 611
Score = 398 bits (1014), Expect = e-109
Identities = 106/458 (23%), Positives = 179/458 (38%), Gaps = 55/458 (12%)
Query: 6 RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
R+ G GGA+ + G++ G++ +P F CL + A L+ + DE
Sbjct: 28 RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83
Query: 65 HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
+ E H I+G G+ TWE+ IRSY LH AF ++LQ + Y +
Sbjct: 84 TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142
Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
R + + S I +LY YK +G +V+ L + + FC + F S C+
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198
Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
T L M +Y + + +AA A P SA + L + +L + ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247
Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYF 294
K + L L ++D YG VI PLN + +N G D YGT PW++Y
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYL 307
Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
GFL M + F + + L+ + +W + + I H
Sbjct: 308 INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366
Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFL 397
KE RF+ PV P+ + A + ++ + + + W + ++ L
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQKCYH---FVFQRYRLEHYTVTSNWLALGTVFLFGL 423
Query: 398 LATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
L+ + +AL+ G D A + ++
Sbjct: 424 LSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 458
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
Length = 611
Score = 396 bits (1008), Expect = e-109
Identities = 106/458 (23%), Positives = 180/458 (39%), Gaps = 55/458 (12%)
Query: 6 RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
R+ G GGA+ + G++ G++ +P F CL + A L+ + DE
Sbjct: 28 RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83
Query: 65 HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
+ E H I+G G+ TWE+ IRSY LH AF ++LQ + Y +
Sbjct: 84 TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142
Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
R + + S I +LY YK +G +V+ L + + FC + F S C+
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198
Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
T L M +Y + + +AA A P SA + L + +L + ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247
Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYF 294
K + L L ++D YG VI PLN + +N G D YGT PW++Y
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYL 307
Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
+GFL M + F + + L+ + +W + + I H
Sbjct: 308 IKGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366
Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFL 397
KE RF+ PV P+ + A + ++ + + + W + ++ L
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQKCYH---FVFQRYRLEHYTVTSNWLALGTVFLFGL 423
Query: 398 LATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
L+ + +AL+ G D A + ++
Sbjct: 424 LSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 458
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
Length = 618
Score = 394 bits (1002), Expect = e-108
Identities = 107/462 (23%), Positives = 180/462 (38%), Gaps = 56/462 (12%)
Query: 6 RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
R+ G GGA+ + G++ G++ +P F CL + A L+ + DE
Sbjct: 28 RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83
Query: 65 HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
+ E H I+G G+ TWE+ IRSY LH AF ++LQ + Y +
Sbjct: 84 TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142
Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
R + + S I +LY YK +G +V+ L + + FC + F S C+
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198
Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
T L M +Y + + +AA A P SA + L + +L + ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247
Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYF 294
K + L L ++D YG VI PLN + +N G D YGT PW++Y
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYL 307
Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
GFL M + F + + L+ + +W + + I H
Sbjct: 308 INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366
Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSS----SSVTKKKQVPRQNHTKWSPKLRLS 393
KE RF+ PV P+ + A + ++ S + + + W +
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVF 426
Query: 394 VYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
++ LL+ + +AL+ G D A + ++
Sbjct: 427 LFGLLSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 465
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
Length = 618
Score = 393 bits (1000), Expect = e-108
Identities = 108/462 (23%), Positives = 181/462 (38%), Gaps = 56/462 (12%)
Query: 6 RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
R+ G GGA+ + G++ G++ +P F CL + A L+ + DE
Sbjct: 28 RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83
Query: 65 HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
+ E H I+G G+ TWE+ IRSY LH AF ++LQ + Y +
Sbjct: 84 TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142
Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
R + + S I +LY YK +G +V+ L + + FC + F S C+
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198
Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
T L M +Y + + +AA A P SA + L + +L + ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247
Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFN-FLSSGGDYYGTHPWHWYF 294
K + L L ++D YG VI PLN + +N F G D YGT PW++Y
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNIFTPHGPDLYGTEPWYFYL 307
Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
GFL M + F + + L+ + +W + + I H
Sbjct: 308 INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366
Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSS----SSVTKKKQVPRQNHTKWSPKLRLS 393
KE RF+ PV P+ + A + ++ S + + + W +
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVF 426
Query: 394 VYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
++ LL+ + +AL+ G D A + ++
Sbjct: 427 LFGLLSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 465
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
musculus]
Length = 611
Score = 385 bits (981), Expect = e-106
Identities = 106/460 (23%), Positives = 180/460 (39%), Gaps = 55/460 (11%)
Query: 8 NAGGDGDGGADGASVNVGDEP----DSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNP 62
+AG + S G EP + G++ +P F CL + A L+ +
Sbjct: 22 DAGPAAEKLEQLGSREAGAEPRPESGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDC 81
Query: 63 DEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYI 116
DE + E H I+G G+ TWE+ IRSY LH AF ++LQ + Y
Sbjct: 82 DETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVFYF 141
Query: 117 MIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNC 173
+ R + + S + +LY YK +G +V+ L + + FC + F S C
Sbjct: 142 L----RCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFC 196
Query: 174 LETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTP 233
+ T L M +Y + + +AA A P SA + L + +L
Sbjct: 197 MYTTLIAMTGWYMDKTPIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLARK 245
Query: 234 NKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHW 292
++ K +L + +L L ++D YG V+ PLN + +N S G D YGT PW++
Sbjct: 246 HRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVLYNVFTSHGPDLYGTEPWYF 305
Query: 293 YFTQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSIL 335
Y GFL M + F + + L+ + +W + + I
Sbjct: 306 YLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQ 364
Query: 336 GHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVY 395
HKE RF+ PV P+ + A + ++ + + + W + ++
Sbjct: 365 PHKEERFLFPVYPLICLCGAVALSALQKCYH---FVFQRYRLEHYTVTSNWLALGTVFLF 421
Query: 396 FLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
LL+ + +AL+ G D A + ++
Sbjct: 422 GLLSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 458
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
could be the target of the GPI synthesis inhibitor,
YW3548; Most likely an alpha 1,2 mannosyltransferase
utilized for the addition of the third mannose onto the
GPI core structure.; Gpi1>
sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
cerevisiae)
emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
Length = 616
Score = 351 bits (892), Expect = 2e-95
Identities = 122/489 (24%), Positives = 214/489 (42%), Gaps = 84/489 (17%)
Query: 115 YIMIKAPRLMQSIFSAIGDLYLYKLSDALY------------------GGNVATWSLFCQ 156
Y +I AP+++ ++ ++IG+ Y+ + LY + ++L
Sbjct: 135 YGVIYAPKIVMAVLASIGEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFALLLS 194
Query: 157 MANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPT 216
+ N+F F + RTF N E +LT + LYYW I + L+ A LAC RP+
Sbjct: 195 LTNFFNCFFITRTFINSFEMILTSIALYYWDWTGGQMI-KESSFTKSLIFAFLACLQRPS 253
Query: 217 SAVIWLYVGMLELFLTPNKVKFIIL-----EVIPIGSLVLGFTCLLDRLMYGSWVIVPLN 271
S +IW+ + + K ++ +L +V+ LV ++D Y
Sbjct: 254 SGLIWVIPSISLILNLVGKKQYHLLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPFFR 313
Query: 272 FLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK----------- 320
FLKFNF + +YG PWH++F Q ++L P G+ +++
Sbjct: 314 FLKFNFTTPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFF 373
Query: 321 -LSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVP 379
+ IL L +YS L HKEFRF+ P+ P+ ++ S + +++
Sbjct: 374 QVKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLD----------------- 416
Query: 380 RQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLM 439
+++ K L+ ++ + ++ +AL + FH+ G+ + M +L +E + S+ F+M
Sbjct: 417 -RDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVMKFLHEEP---EIDSLGFIM 472
Query: 440 PCHSTPYYSTLH-----------RNIPMQFLDCTPSAEKG--ELDESDQFLVN------- 479
PCHSTP S LH N P+ L + K +DESD +
Sbjct: 473 PCHSTPGQSYLHRSDIQDLWSITCNPPLHLLGDPEAYSKLETYMDESDHLYDDISAFIYK 532
Query: 480 --PLGFASEL---ARNWS-EPPSHIVLFASEETK-LRDFMIQHSFKEVRRFFHAHFKVDR 532
P F +L + +S E P+++V+F E L+DF+ S+ E RFF++ D
Sbjct: 533 NFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENAFLKDFLKDSSYIEYNRFFNSLAHWDS 592
Query: 533 DLQSSVVVY 541
+++Y
Sbjct: 593 RRSGDIIIY 601
Score = 88.7 bits (218), Expect = 2e-16
Identities = 38/73 (52%), Positives = 52/73 (71%)
Query: 39 RRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPML 98
+IF LAFRV+NA+L +T+F DE WQ+LE AH F YG +TWEWK G+RSYL PM+
Sbjct: 15 TQIFWVFLAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYGELTWEWKFGVRSYLFPMI 74
Query: 99 FAFLYKLLQVTGL 111
F Y+L+ ++ +
Sbjct: 75 FELTYRLVSLSSI 87
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
Length = 623
Score = 343 bits (873), Expect = 3e-93
Identities = 93/440 (21%), Positives = 160/440 (36%), Gaps = 39/440 (8%)
Query: 8 NAGGDGDGGADGASVNV--GDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYFNPDEH 65
AG D A + G E + S + F ++ R+ +A+ + DE
Sbjct: 41 PAGKKKDKDAKKRNQPTSGGQEKGLPNPIMPSVQTAFKTFVSARLCSAIW-AYIADCDET 99
Query: 66 WQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRL 123
+ E H I G+G TWE+ G+RSY + +L Q +P ++ R
Sbjct: 100 FNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPGYFYQKLFNPSPILIFYMVRC 159
Query: 124 MQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGL 183
M A+ + Y+YK +G ++ L Q+ + +F + L
Sbjct: 160 MLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFSMYFGCAAL 219
Query: 184 YYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILE 242
W + N + + + A++ + P +A+I + + + E+ L K +
Sbjct: 220 AAW---------WQQNYCFAIFLTAISALLGWPFAALIGIPLVL-EMLLRQRDWKTFVQW 269
Query: 243 VIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYFTQGFLV- 300
+ G+ V +D +G PLN + +N S G + +GT P +Y GFL
Sbjct: 270 TLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNF 329
Query: 301 --MLFTFTPFSIAGIIK--------------SKNQKLSALILWVLAIYSILGHKEFRFVL 344
+ I +I L+ L LW+L + HKE RF+
Sbjct: 330 NIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFF-AQPHKEERFLF 388
Query: 345 PVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQ-VPRQNHTKWSPKLRLSVYFLLATNIP 403
P+ P+ + + S V K K V +H+ + L + LL +
Sbjct: 389 PIYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRV 448
Query: 404 MALYMSLFHQRGTEDAMNYL 423
ALY + D M L
Sbjct: 449 FALYRNY---HAPMDLMLEL 465
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
Length = 558
Score = 323 bits (820), Expect = 7e-87
Identities = 124/480 (25%), Positives = 213/480 (43%), Gaps = 92/480 (19%)
Query: 38 PRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPM 97
P + +R+ I+T PDE WQS EVA+ +FG G++ WEW+ G+RS L P
Sbjct: 2 PWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPA 61
Query: 98 LFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYK---------------LSDA 142
+ A + LL++ G DT + + APR++Q++ + D+ ++ L++
Sbjct: 62 VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121
Query: 143 LYGGNVATWSLFC----------------------QMANWFIFFCLNRTFSNCLETVLTI 180
+S FC ++NW++ +C R + N +E +L +
Sbjct: 122 TRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVL 181
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKF-- 238
+ L L++ LA AIR TSAV+ + L + F
Sbjct: 182 LTLQ------------QRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIR 229
Query: 239 ----IILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYF 294
I+L + + VLG +LD YG WV+ PL F +FN L + ++G HPW++Y
Sbjct: 230 GLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYV 289
Query: 295 TQGFLVMLFTFTPFSIAGII----KSKNQKLSALIL-------WVLAIYSILGHKEFRFV 343
+ ++ F+IA + + ++ +S +L W L YS++ HKE RFV
Sbjct: 290 GPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFV 349
Query: 344 LPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIP 403
V+P++LI + + V S +S+ V K + ++ L NI
Sbjct: 350 FVVIPLSLITAAFVL----VRWSRTSAVVVKMNR----------------LFVL--FNIV 387
Query: 404 MALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIP-MQFLDCT 462
M M ++RG D M + D R+ + + C++ P YS +H+ + + F+DC+
Sbjct: 388 MIYLMGYVYRRGPLDVMAEVRDGP---RINRLDVIATCYTVPGYSYMHKKVNHLGFVDCS 444
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
Length = 509
Score = 309 bits (785), Expect = 7e-83
Identities = 85/432 (19%), Positives = 151/432 (34%), Gaps = 24/432 (5%)
Query: 41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFA 100
I L L R+ I Y++PDE +Q LE AHR FGY + WE++ G+R L P+L A
Sbjct: 26 ITLLALCLRMTAIFPIG-YYHPDEIFQYLEQAHRLAFGYSVIPWEYRYGMRGGLVPVLLA 84
Query: 101 FLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANW 160
K+ + + + P + ++ S YKL L+ ++F +
Sbjct: 85 AAMKMGDIMNTQSF-LYWVLPHAITALLSLGVIWSAYKLG-RLHSFFTGCLAMFVAATWY 142
Query: 161 FIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVI 220
I S L + YY ++ + L+ +R
Sbjct: 143 EIVLFAAHPLSESLSFAAFMPAAYYLIAEEKKKSSLILSG----FLMGLSALLRFQYIPS 198
Query: 221 WLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSS 280
L++ + L + + + IL + + + + + N + N +
Sbjct: 199 ILFITLFTLRINVRQWGYFILGGLGAVFISSLSDIFIGEY---PLLWLFKNI-QQNLIFH 254
Query: 281 GGDYYGTHPWHWYFTQGFLV-MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKE 339
+ YGT P + YF + F+ + + L L L + ++ HKE
Sbjct: 255 RAEDYGTAPIYSYFFDIWTNWKWFSLILPIPILVAAYRYPALFGTALVNLIFHMLVSHKE 314
Query: 340 FRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLA 399
+RF+ I +I + + + + ++ + + KK T W FL +
Sbjct: 315 YRFIFLSSGIFIILAAIG-SALLIEKATINFTPLHKKLAQIAAFTAWGA-----CSFLCS 368
Query: 400 TNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFL 459
T Y RG A + L+ + + YS LHR IP+ L
Sbjct: 369 TGNISHWY----QYRGVLQAEMKARSLS--NLCGLTLYQIDYWESGGYSLLHRPIPIYSL 422
Query: 460 DCTPSAEKGELD 471
+ D
Sbjct: 423 LPSNMYSTRYPD 434
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
Length = 678
Score = 287 bits (729), Expect = 3e-76
Identities = 66/372 (17%), Positives = 142/372 (37%), Gaps = 34/372 (9%)
Query: 67 QSLEVAHRTIFGYGYMTWEWKRGIRSYLHPM-------LFAFLYKLLQVTGLDTPYIMIK 119
+ + G + R+++ P+ F L++ L + Y++
Sbjct: 38 NNFTQYDHHDYP-GVVP-------RTFIGPLVVSIISAPFVLLFETLSINKFWAQYVV-- 87
Query: 120 APRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLT 179
RL+ + ++ L + +YG V W + + F + R N +
Sbjct: 88 --RLVLAGAISVAWNSLRQAVTKIYGVEVRLWFTAITITQFHFMFYMTRPLPNIFALPIV 145
Query: 180 IMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKF 238
+ + YW K ++ + ++ + R A+ + ++ L +
Sbjct: 146 LFAIAYW---------LRDQHKPFIICSGISILVFRSELALFLGILLVVSLLRRKVSIDG 196
Query: 239 IILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGF 298
++ +P G +L T L+D + + L +N + + +GT P+ WYF
Sbjct: 197 LLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYNTVLNKSSNWGTSPFLWYFYSAL 256
Query: 299 LVMLFTFTPFSIAGI-IKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYA 357
+ G+ ++ + + L L + +YSIL HKE RF++ V P+ I + A
Sbjct: 257 PRAMGASLVLVPIGVALEPRIRPLVLSALLFVLLYSILPHKELRFIIYVFPVLNIAAACA 316
Query: 358 FAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFH--QRG 415
++ ++ S+ S+ + H + + L + + TN P +S H + G
Sbjct: 317 CQRIWMN--SAKSTWHSFLALACGAHLLLNVFITLFLLVISGTNYPGGAALSRLHRLEAG 374
Query: 416 TEDAMNYLSDEA 427
T + ++S+ A
Sbjct: 375 TSNVSVHISNLA 386
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
Length = 919
Score = 274 bits (696), Expect = 2e-72
Identities = 102/511 (19%), Positives = 169/511 (32%), Gaps = 52/511 (10%)
Query: 4 RKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFC----LAFRVVNALLIQTY 59
R+R+ D + S + D+P G + F L + +
Sbjct: 356 RQRRPLISDSSSSSSTKSYSKTDKPGRSNGGDAEDGGLRWFLPFIALCYLRYMSATSNII 415
Query: 60 FNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIM 117
+ DE + E H ++ G+ TWE+ +RSYL+ + + D +
Sbjct: 416 HDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFHELAGRPASWWFGDDKVRV 475
Query: 118 IKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETV 177
A RL + SA+ D L YG +AT+++ FF +
Sbjct: 476 FYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLTSGCFFASTSFLPSSFSM- 534
Query: 178 LTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI---RPTSAVIWLYVGMLELFLTPN 234
S + K+ + +A + P S + +L V + L +
Sbjct: 535 ----------YAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSL-VKRF 583
Query: 235 KVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSG-GDYYGTHPWHWY 293
K FI V I L G + L+D Y W LN L +N L G YGT +Y
Sbjct: 584 KQAFIAGAVTTIFLL--GVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFY 641
Query: 294 F--------TQGFLVMLFTFTPFSIAGIIKSKNQ-KLSALILWVLAIYSILGHKEFRFVL 344
L MLF I +S + +W LA S+ HKE RF+
Sbjct: 642 IRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW-LAFMSLQPHKEERFLY 700
Query: 345 PVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPM 404
P+ P+ + + A + S + V + + + L + +
Sbjct: 701 PIYPLICVSAS-AVIENIPELFREKYSSRESLLVTITKYMR---PVILGCILCASHSRTF 756
Query: 405 ALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPS 464
AL + L G S+L C + ++ P F
Sbjct: 757 ALINGY---SAPLEVYKLLEHHDDAGP-GSVL----CVGSEWHRY-----PSSFFVPHYI 803
Query: 465 AEKGELDESDQFLVNPLGFASELARNWSEPP 495
+E +D+ + L+ P F + L + PP
Sbjct: 804 SEVRWIDDGFRGLL-PFPFNNTLGGTSASPP 833
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
lipid-linked oligosaccharides; Alg9p [Saccharomyces
cerevisiae]
sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
cerevisiae)
emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
Length = 555
Score = 262 bits (664), Expect = 1e-68
Identities = 65/326 (19%), Positives = 112/326 (33%), Gaps = 10/326 (3%)
Query: 41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPML 98
+ L RV + DE + E + + G+G TWE+ IRS+ +
Sbjct: 10 LLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYSIRSWAFLLP 69
Query: 99 FAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMA 158
F + + + R FS I + L++ +A + Q+
Sbjct: 70 FYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQIANIWIIFQLF 129
Query: 159 NWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSA 218
N F + + +L + + +R S N L LA +
Sbjct: 130 NPGWFHASVELLPSAVAMLLYVGATRHS--LRYLSTGSTSNFTKSLAYNFLASILGWPFV 187
Query: 219 VIWLYVGMLELFLTPNKVKFIILEV--IPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFN 276
+I L + I I SL + D + YG V N L +N
Sbjct: 188 LILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAPVSWNILFYN 247
Query: 277 FL----SSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIY 332
+ SG + +G PW++Y L +I GI + L A + +A++
Sbjct: 248 VINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHLRLWPLWASLFTWIAVF 307
Query: 333 SILGHKEFRFVLPVLPIALIFSGYAF 358
+ HKE RF+ P+ + + + AF
Sbjct: 308 TQQPHKEERFLYPIYGLITLSASIAF 333
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
Length = 570
Score = 259 bits (656), Expect = 1e-67
Identities = 88/439 (20%), Positives = 144/439 (32%), Gaps = 41/439 (9%)
Query: 4 RKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFC----LAFRVVNALLIQTY 59
R+R+ D + S + D+P G + F L + +
Sbjct: 7 RQRRPLISDSSSSSSTKSYSKTDKPGRSNGGDAEDGGLRWFLPFIALCYLRYMSATSNII 66
Query: 60 FNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIM 117
+ DE + E H ++ G+ TWE+ +RSYL+ + + D +
Sbjct: 67 HDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFHELAGRPASWWFGDDKVRV 126
Query: 118 IKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETV 177
A RL + SA+ D L YG +AT+++ FF +
Sbjct: 127 FYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLTSGCFFASTSFLPSSFSM- 185
Query: 178 LTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI---RPTSAVIWLYVGMLELFLTPN 234
S + K+ + +A + P S + +L V + L +
Sbjct: 186 ----------YAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSL-VKRF 234
Query: 235 KVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSG-GDYYGTHPWHWY 293
K FI V I L G + L+D Y W LN L +N L G YGT +Y
Sbjct: 235 KQAFIAGAVTTIFLL--GVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFY 292
Query: 294 F--------TQGFLVMLFTFTPFSIAGIIKSKNQ-KLSALILWVLAIYSILGHKEFRFVL 344
L MLF I +S + +W LA S+ HKE RF+
Sbjct: 293 IRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW-LAFMSLQPHKEERFLY 351
Query: 345 PVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPM 404
P+ P+ + + A + S + V + + + L + +
Sbjct: 352 PIYPLICVSAS-AVIENIPELFREKYSSRESLLVTITKYMR---PVILGCILCASHSRTF 407
Query: 405 ALYMSLFHQRGTEDAMNYL 423
AL + L
Sbjct: 408 ALINGY---SAPLEVYKLL 423
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
(Swiss Prot accession number P38376)~cDNA EST yk549e12.3
comes from this gene~cDNA EST yk618d6.3 comes from this
gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
yk618d6.5 comes from>
Length = 653
Score = 251 bits (636), Expect = 2e-65
Identities = 85/360 (23%), Positives = 134/360 (36%), Gaps = 49/360 (13%)
Query: 19 GASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFG 78
A+ D P SFG +F L+ R+ A+ + DE + E H ++G
Sbjct: 41 KANNPDNDWPFSFGS-------VFKMLLSIRISGAIW-GIINDCDEVYNYWEPLHLFLYG 92
Query: 79 YGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYL 136
G+ TWE+ IRSY + L L DT ++ RL +F +G+ Y
Sbjct: 93 EGFQTWEYSPVYAIRSYFYIYLHYIPASLFANLFGDTKIVVFTLIRLTIGLFCLLGEYYA 152
Query: 137 YKLSDALYGGNVATWSLFCQMANWFIFFCLNR--TFSNCLETVLTIMGLYYWPCIRDSSI 194
+ + + + + +F S C+ I+G Y
Sbjct: 153 FDAICKKINIATGRFFILFSIFSSGMFLASTAFVPSSFCMAITFYILGAY---------- 202
Query: 195 DYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGF 253
N G+ A + + P SAV+ L + L L +++FI+ + IG + G
Sbjct: 203 -LNENWTAGIFCVAFSTMVGWPFSAVLGLPIVADMLLLKGLRIRFILT-SLVIGLCIGGV 260
Query: 254 TCLLDRLMYGSWVIVPLNFLKFNFLSS-GGDYYGTHPWHWYFTQGF-------LVMLFTF 305
+ D +G V+ PLN +N +S G YG P +Y F F F
Sbjct: 261 QVITDSHYFGKTVLAPLNIFLYNVVSGPGPSLYGEEPLSFYIKNLFNNWNIVIFAAPFGF 320
Query: 306 TPFSIAGIIKSK---------NQKLSALILW------VLAIYSILGHKEFRFVLPVLPIA 350
P S+A K Q+ + +IL L I+ HKE RF+ P+ P
Sbjct: 321 -PLSLAYFTKVWMSQDRNVALYQRFAPIILLAVTTAAWLLIFGSQAHKEERFLFPIYPFI 379
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
Length = 483
Score = 249 bits (631), Expect = 9e-65
Identities = 78/393 (19%), Positives = 136/393 (33%), Gaps = 43/393 (10%)
Query: 40 RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGY------------GYMTWEWK 87
L L L+I Y +E + L+ H ++ G +
Sbjct: 12 WPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHHEFPGVVP---- 66
Query: 88 RGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDAL 143
R++L P++ A + +L + + Y R + + G L K
Sbjct: 67 ---RTFLGPLVIAAFSSPVVYVLSLLEVSKFYS-QLIVRGVLGLGVISGLWTLQKEVRQQ 122
Query: 144 YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWG 203
+G VA + + + F RT N L + + L W + R+W
Sbjct: 123 FGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAW-----------LQRRWA 171
Query: 204 LVI---AALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRL 260
L + A + R A++ +L L+ V ++ IP G L LG T +D
Sbjct: 172 LFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSY 231
Query: 261 MYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK 320
+ V L +N + + +GT P WYF L F G + +
Sbjct: 232 FWRYLVWPEGVVLGYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYA 291
Query: 321 LSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPR 380
L+ L +A+YS+L HKE RF++ P+ I + + S K + +
Sbjct: 292 LALPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILNK----KSWPYKVRAMLV 347
Query: 381 QNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
H + + ++ N P + M H+
Sbjct: 348 TGHILVNVAYTATSLYVSHFNYPGGVAMQQLHE 380
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
Length = 488
Score = 247 bits (627), Expect = 2e-64
Identities = 73/354 (20%), Positives = 126/354 (34%), Gaps = 25/354 (7%)
Query: 65 HWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKA 120
HWQ LE F G + R++L P++ A +L + + Y
Sbjct: 48 HWQDLEQYDHLEFP-GVVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFYS-QLI 98
Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
R + + G L K +G VAT + + + F RT N L + +
Sbjct: 99 VRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVL 158
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFI 239
+ L W + ++A A + R + + +L L V
Sbjct: 159 LALAAW---------LRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRA 209
Query: 240 ILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL 299
+ +P G L LG T +D + L +N + + +GT P WYF
Sbjct: 210 LRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALP 269
Query: 300 VMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFA 359
L F G++ + + L L +A+YS+L HKE RF++ P+ I + +
Sbjct: 270 RGLGCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCS 329
Query: 360 QMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
+ + S + K + H + + ++ N P + M HQ
Sbjct: 330 YLLNNYK--KSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQ 381
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
mannosyltransferase [Homo sapiens]
Length = 488
Score = 247 bits (626), Expect = 4e-64
Identities = 72/354 (20%), Positives = 125/354 (34%), Gaps = 25/354 (7%)
Query: 65 HWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKA 120
HWQ LE F G + R++L P++ A +L + + Y
Sbjct: 48 HWQDLEQYDHLEFP-GVVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFYS-QLI 98
Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
R + + G L K +G VAT + + + RT N L + +
Sbjct: 99 VRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMVYCTRTLPNVLALPVVL 158
Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFI 239
+ L W + ++A A + R + + +L L V
Sbjct: 159 LALAAW---------LRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRA 209
Query: 240 ILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL 299
+ +P G L LG T +D + L +N + + +GT P WYF
Sbjct: 210 LRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALP 269
Query: 300 VMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFA 359
L F G++ + + L L +A+YS+L HKE RF++ P+ I + +
Sbjct: 270 RGLGCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCS 329
Query: 360 QMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
+ + S + K + H + + ++ N P + M HQ
Sbjct: 330 YLLNNYK--KSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQ 381
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
most likely an alpha 1,2 mannosyltransferase utilized
for addition of the fourth, side-branching mannose onto
the GPI core structure.; Smp3p [Saccharomyces
cerevisiae]
sp|Q04174|SMP3_YEAST SMP3 PROTEIN
pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
Length = 516
Score = 239 bits (606), Expect = 7e-62
Identities = 79/395 (20%), Positives = 146/395 (36%), Gaps = 42/395 (10%)
Query: 39 RRIFLFCLAFRVVNALLIQ-TYFNPDEHWQSLEVAHRTIFG-YGYMTWEW--KRGIRSYL 94
R + L + + L + +Y +PDEH+Q +E+ G + WE+ K RSY
Sbjct: 3 RYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYG 62
Query: 95 HPMLFAFLYKLLQVTG---LDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW 151
+L + + D P +++ + RL + + +L V
Sbjct: 63 PLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFM 122
Query: 152 SLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYW-PCIRDSSIDYPVNRKWGLVIAALA 210
+ ++ + TFSN +ET+ I L + + +I + ++ +
Sbjct: 123 QKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFS 182
Query: 211 CAIR---PTSAVIWLY-VGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMY---G 263
+ A I+L + + F + F +L + S L+D +Y
Sbjct: 183 FGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLL--SFSFSSCLFVLIDTNIYNNGK 240
Query: 264 SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSA 323
+VI PLN LK+N +G HP + + ++ +I K A
Sbjct: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYA 300
Query: 324 LILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNH 383
+I +L + S H+E RF++P++P+ + ++ + SS++ KK
Sbjct: 301 IISGLLFL-SFFQHQELRFLVPLVPLLVTN---------LNWTPLSSTLVNKKIFKGTW- 349
Query: 384 TKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
L NI MA M + HQ G
Sbjct: 350 --------------LLFNIIMAFIMGISHQAGIIQ 370
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
Length = 516
Score = 237 bits (599), Expect = 5e-61
Identities = 80/395 (20%), Positives = 145/395 (36%), Gaps = 42/395 (10%)
Query: 39 RRIFLFCLAFRVVNALLIQ-TYFNPDEHWQSLEVAHRTIFG-YGYMTWEW--KRGIRSYL 94
R + L + + L + +Y +PDEH+Q +E+ G + WE+ K RSY
Sbjct: 3 RYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYG 62
Query: 95 HPMLFAFLYKLLQVTG---LDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW 151
+L + + D P +++ + RL + + +L V
Sbjct: 63 PLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFI 122
Query: 152 SLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYW-PCIRDSSIDYPVNRKWGLVIAALA 210
+ ++ + TFSN +ET+ I L + +I + ++ +
Sbjct: 123 KKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNGKNIQRRNFKNSVILGLIFS 182
Query: 211 CAIR---PTSAVIWLY-VGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMY---G 263
+ A I+L + + F + F +L + S L+D +Y
Sbjct: 183 FGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLL--SFSFSSCLFVLIDTNIYNNGK 240
Query: 264 SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSA 323
+VI PLN LK+N +G HP + + +L +I K A
Sbjct: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQILGPVLLLAIFSGYKLDKLSTYA 300
Query: 324 LILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNH 383
+I +L + S H+E RF++P++P+ + ++ + SS++ KK
Sbjct: 301 IISGLLFL-SFFQHQELRFLVPLVPLLVTN---------LNWTPLSSTLVNKKIFKGTW- 349
Query: 384 TKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
L NI MA M + HQ G
Sbjct: 350 --------------LLFNIIMAFIMGISHQAGIIQ 370
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
- fission yeast (Schizosaccharomyces pombe)
emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
[Schizosaccharomyces pombe]
Length = 577
Score = 232 bits (587), Expect = 1e-59
Identities = 102/519 (19%), Positives = 177/519 (33%), Gaps = 52/519 (10%)
Query: 37 SPRRIFLF-CLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSY 93
S ++ F LA + + + + DE + E H ++GYG TWE+ IRS+
Sbjct: 11 SVSFVWTFSILAVLRLTSASFRVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPEYAIRSW 70
Query: 94 LHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSL 153
+ L A L + GL + + R + + FSA + L + VA
Sbjct: 71 FYIALHAVPGFLARGLGLSRLH-VFYFIRGVLACFSAFCETNLILAVARNFNRAVALHLT 129
Query: 154 FCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI 213
N ++ + + + L + S K I A
Sbjct: 130 SVLFVNSGMWSASTSFLPSSFAMNMVTLALSA----QLSPPSTKRTVKVVSFITIGAVIG 185
Query: 214 RPTSAVIWLYVGMLELF-LTPNKVKFIILEV--IPIGSLVLGFTCLLDRLMYGSWVIVPL 270
P SA + + +LEL L I + L+ G +D L Y V
Sbjct: 186 WPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQFVAW 245
Query: 271 NFLKFNFLSS---GGDYYGTHPWHWYFTQ---------------GFLVMLFTFTPFSIAG 312
N +K+N L+ G D YGT PW +YF G LV+L FT +
Sbjct: 246 NIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLVLLAAFTNWINLD 305
Query: 313 IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSV 372
+ +S +W L I+ I HKE RF+ P+ P+ + + S +
Sbjct: 306 SFLDLSSVISPFYIW-LFIFIIQPHKEERFMYPIYPVLCLAAAIGLD------MSLKLMI 358
Query: 373 TKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRV 432
+ +K+ + + + + + +A +++ + +S V
Sbjct: 359 QILSSINETVRSKFPVRFVVLCVYAIIGCLSIARILAIQNYNAPMIIYPAISFLETDNNV 418
Query: 433 KSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESD-----QFLVNPLGFASEL 487
+ + C +Y P F S K E D +F+ + + +
Sbjct: 419 TTNV----CVGKEWYRY-----PSTFFLPDNSRLKFVKSEFDGILPGEFVESNSTWWNRE 469
Query: 488 ARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHA 526
+ + P H+ F +EE + F F H+
Sbjct: 470 G--YYQIPEHMNEFNNEEPTRYTSLESCDFLIDLEFDHS 506
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
Length = 533
Score = 226 bits (573), Expect = 6e-58
Identities = 85/408 (20%), Positives = 156/408 (37%), Gaps = 66/408 (16%)
Query: 41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGY-MTWEW--KRGIRSYLHP- 96
I+ F L R + +Y +PDEH QS ++ +FG+ + WE+ K+ IRS +
Sbjct: 10 IYTFLLILRFWFSQ-GSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSVVPLN 68
Query: 97 --MLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLF 154
+L FL +PY ++ RL + S + DL ++ + A WS
Sbjct: 69 VMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLIDLSIWNIVPL-----NARWSAL 123
Query: 155 CQMANWFIF-FCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIA------ 207
++ F+ TF+N +ET+ + + + + ++ ++ + ++A
Sbjct: 124 LLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIVSVLG 183
Query: 208 ------ALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLL-DRL 260
LA I P I+ V + + K F+ L + S C+L D
Sbjct: 184 FFTRITFLAFVIAP---YIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDYK 240
Query: 261 MYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK 320
YG +VI N LK+N +G H +F ++ + K + +
Sbjct: 241 FYGVFVITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGPLI-----FVPKLWDVR 295
Query: 321 LSALILWVL--AIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQV 378
A LW+L I S+ H+E RF+LP I ++ SG +
Sbjct: 296 KPATWLWLLPVFILSLFPHQEPRFLLPAASIFIVNSGCLVRSYWIK-------------- 341
Query: 379 PRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDE 426
++ + A + +A++ + HQ G A+ + +
Sbjct: 342 --------------FLFVMYA--VVLAVFFGIMHQNGVIPAVLEVKNI 373
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
Length = 492
Score = 216 bits (546), Expect = 8e-55
Identities = 50/289 (17%), Positives = 108/289 (37%), Gaps = 19/289 (6%)
Query: 91 RSYLHPMLFAFLYKLLQVTGLDTPYIM-----IKAPRLMQSIFSAIGDLYLYKLSDALYG 145
R+++ P+ A L + + + + R + +A+ LY + + +G
Sbjct: 58 RTFIGPISLAILSSPMSFIFR--FWAIPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFG 115
Query: 146 GNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLV 205
A + + F ++R N +L ++ R Y ++
Sbjct: 116 RETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVF-----ERLLEGRYESAVRYA-- 168
Query: 206 IAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEV---IPIGSLVLGFTCLLDRLMY 262
A R +++ + + + KV + + I ++ L + +D +
Sbjct: 169 -TASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFW 227
Query: 263 GSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL-VMLFTFTPFSIAGIIKSKNQKL 321
G + + FN + + YGT P+ WYF +L T + ++ + ++
Sbjct: 228 GRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQI 287
Query: 322 SALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSS 370
+ + +YS L HKE RF++ VLPI + + A+M ++ S
Sbjct: 288 VLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFF 336
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
Length = 278
Score = 215 bits (544), Expect = 1e-54
Identities = 67/283 (23%), Positives = 122/283 (42%), Gaps = 60/283 (21%)
Query: 298 FLVMLFTFTPFSIAGIIKSKNQK------------LSALILWVLAIYSILGHKEFRFVLP 345
++L P G+ +++ + IL L +YS L HKEFRF+ P
Sbjct: 2 LPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIFP 61
Query: 346 VLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMA 405
+ P+ ++ S + +++ +++ K L+ ++ + ++ +A
Sbjct: 62 LQPLFILISSFGLLRLD------------------RDYWKRLSGLKSLLWLVPFVSVFIA 103
Query: 406 LYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLH-----------RNI 454
L + FH+ G+ + M +L +E + S+ F+MPCHSTP S LH N
Sbjct: 104 LLLDTFHESGSIEVMKFLHEEP---EIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCNP 160
Query: 455 PMQFLDCTPSAEKG--ELDESDQFLVN---------PLGFASEL---ARNWS-EPPSHIV 499
P+ L + K +DESD + P F +L + +S E P+++V
Sbjct: 161 PLHLLGDPEAYSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLV 220
Query: 500 LFASEETK-LRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVVY 541
+F E L+DF+ S+ E RFF++ D +++Y
Sbjct: 221 VFEHMENAFLKDFLKDSSYIEYNRFFNSLAHWDSRRSGDIIIY 263
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
Length = 369
Score = 210 bits (530), Expect = 7e-53
Identities = 50/289 (17%), Positives = 108/289 (37%), Gaps = 19/289 (6%)
Query: 91 RSYLHPMLFAFLYKLLQVTGLDTPYIM-----IKAPRLMQSIFSAIGDLYLYKLSDALYG 145
R+++ P+ A L + + + + R + +A+ LY + + +G
Sbjct: 16 RTFIGPISLAILSSPMSFIFR--FWAIPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFG 73
Query: 146 GNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLV 205
A + + F ++R N +L ++ R Y ++
Sbjct: 74 RETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVF-----ERLLEGRYESAVRYA-- 126
Query: 206 IAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEV---IPIGSLVLGFTCLLDRLMY 262
A R +++ + + + KV + + I ++ L + +D +
Sbjct: 127 -TASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFW 185
Query: 263 GSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL-VMLFTFTPFSIAGIIKSKNQKL 321
G + + FN + + YGT P+ WYF +L T + ++ + ++
Sbjct: 186 GRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQI 245
Query: 322 SALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSS 370
+ + +YS L HKE RF++ VLPI + + A+M ++ S
Sbjct: 246 VLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFF 294
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
Length = 579
Score = 209 bits (529), Expect = 7e-53
Identities = 91/394 (23%), Positives = 138/394 (34%), Gaps = 74/394 (18%)
Query: 16 GADGASVNVGDEPDSFGGRIG-------SPRRIFLFCLAFRVVNALLIQT-YFNPDEHWQ 67
G+ ASV G G + R ++ RV+ LL QT Y +PDE +Q
Sbjct: 5 GSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLLPQTGYVHPDEFFQ 64
Query: 68 SLEVAHRTIFG-YGYMTWEW--KRGIRSYLHPMLF-AFLYKLLQVT-------GLDTPYI 116
S EV I G WE+ RS L P+L + LL++ GL + Y
Sbjct: 65 SPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGSTFWLLRLWEELGPWPGLVSGYA 124
Query: 117 MIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMA-NWFIFFCLNRTFSNCLE 175
++ PRL+ + S D +Y L+ + W+ ++ ++ RTFSN +E
Sbjct: 125 LLVGPRLLLTALSFALDGAVYHLAPPMGAD---RWNALALLSGSYVTLVFYTRTFSNTIE 181
Query: 176 TVLTIMGLYY------WPCIRDSSIDYPVNRKWGLV----------IAALACAIRPTSAV 219
+L L W R P R W L LA A+ P
Sbjct: 182 GLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWLLGGIVAAGFFNRPTFLAFAVVP--LY 239
Query: 220 IWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMY------GSWVIVPLNFL 273
+W G L + L ++P +L D + + V+ P+NFL
Sbjct: 240 LWGTRGATNPGLKSLTRE--ALVLLPGATLTAAVFVATDSWYFSSPATSRNLVLTPVNFL 297
Query: 274 KFNFLSSGGDYYGTHPWHWYF-TQGFL------------------VMLFTFTPFSIAGII 314
+N +GTH + GFL V L + +
Sbjct: 298 HYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQQLQVGLQASAQMGLLRAL 357
Query: 315 KSKNQ------KLSALILWVLAIYSILGHKEFRF 342
+++ L L LA+ S H+E RF
Sbjct: 358 GARSLLSSPRSYLLLLYFMPLALLSAFSHQEARF 391
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
(Schizosaccharomyces pombe)
emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
architecture [Schizosaccharomyces pombe]
Length = 547
Score = 202 bits (511), Expect = 1e-50
Identities = 57/355 (16%), Positives = 121/355 (34%), Gaps = 34/355 (9%)
Query: 66 WQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQ 125
W +V F RS++ + A L + + A R
Sbjct: 49 WDLSKVYDHLEFPGAVK--------RSFIPSLFIAVLSYIPSWFVNP-----LLAARWTI 95
Query: 126 SIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYY 185
S + +G + A + + + ++R SN + T
Sbjct: 96 GYLSWESMNSVSCSISKRFGTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIAT------ 149
Query: 186 WPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILEVI 244
S+ N + I A AI R A++ + + + L + ++L I
Sbjct: 150 ---NHSLSLLLKNNYYGSISILVFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGI 206
Query: 245 PIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFT 304
+G + L+D +G+W L FN + +GT P+++YF + + +
Sbjct: 207 SSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFYYYF----VRLPWL 262
Query: 305 FTPFSIAGIIKSKNQKLSA------LILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
F + + + + L+ + +YS LGHKE+RF++ +P S
Sbjct: 263 FLNPTTLLFLLISFVYIKPARLLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAASAIG- 321
Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
A + + S + + ++ + + + ++ P L ++ ++
Sbjct: 322 ASLCFNASKFGKKIFEILRLMFFSGIIFGFIGSSFLLYVFQYAYPGGLALTRLYE 376
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
chromosome I precursor [Leishmania major]
Length = 822
Score = 168 bits (422), Expect = 3e-40
Identities = 49/319 (15%), Positives = 97/319 (30%), Gaps = 65/319 (20%)
Query: 44 FCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEW--KRGIRSYLHPMLFAF 101
L+ A + DE + +E H ++G G TWE + +RS+L + A+
Sbjct: 16 LLLSLTHYFASSFLPISDCDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSWLFLWIHAW 75
Query: 102 LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWF 161
L++ + + R++ +A+ +L+ G A +L +AN+
Sbjct: 76 PVVLIRGAASLSSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLLANYP 135
Query: 162 IFFCLNRTFSNCLETVLTIMGLYYW----PCIRDSSI----------------------- 194
I + + L W S++
Sbjct: 136 IQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLSRVGDRPTQNTMPAAAAGTAQL 195
Query: 195 -----DYPVNR------------------KWGLVIAALACAI------RPTSAVIWLYVG 225
P + W + AAL ++ P +A+I VG
Sbjct: 196 SMMVPPSPSSAPTLHSSSASPPSAPPRHLCWFIG-AALCFSVLAVVTGWPFAALISALVG 254
Query: 226 MLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSS---GG 282
+ L P + + + + + D Y W + N + +N G
Sbjct: 255 LDLLLRFPVR---TLACTLGSLLVACAAVFVADVRYYCRWTLSSWNVVMYNGFGGSGRGP 311
Query: 283 DYYGTHPWHWYFTQGFLVM 301
+ +G P +++ L
Sbjct: 312 ELFGVEPIFFFWKNLMLNF 330
Score = 115 bits (286), Expect = 3e-24
Identities = 27/155 (17%), Positives = 55/155 (35%), Gaps = 2/155 (1%)
Query: 44 FCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEW--KRGIRSYLHPMLFAF 101
L+ A + DE + +E H ++G G TWE + +RS+L + A+
Sbjct: 16 LLLSLTHYFASSFLPISDCDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSWLFLWIHAW 75
Query: 102 LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWF 161
L++ + + R++ +A+ +L+ G A +L +AN+
Sbjct: 76 PVVLIRGAASLSSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLLANYP 135
Query: 162 IFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDY 196
I + + L W + +
Sbjct: 136 IQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSS 170
Score = 40.0 bits (93), Expect = 0.11
Identities = 12/38 (31%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 321 LSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
+ +W L SI HKE RF+ P P L+ +
Sbjct: 439 IMPFFVWFLFWMSI-AHKEERFMSPAYPFMLLAATRTL 475
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
Length = 198
Score = 167 bits (420), Expect = 4e-40
Identities = 46/173 (26%), Positives = 75/173 (42%), Gaps = 16/173 (9%)
Query: 6 RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
R+ G GGA+ + G++ G++ +P F CL + A L+ + DE
Sbjct: 28 RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83
Query: 65 HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
+ E H I+G G+ TWE+ IRSY LH AF ++LQ + Y +
Sbjct: 84 TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142
Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFS 171
R + + S I +LY YK +G +V+ L + + FC + +
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSVYP 191
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
cerevisiae)
emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
Length = 551
Score = 161 bits (406), Expect = 2e-38
Identities = 56/335 (16%), Positives = 117/335 (34%), Gaps = 63/335 (18%)
Query: 68 SLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKL------LQVTGLDTPYIMIKAP 121
+ F G + R+++ ++ A L + L T T +
Sbjct: 45 DISQYDHLKFP-GVVP-------RTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVV 96
Query: 122 RLMQSIFSAIGDLYLYKLSDALYGGNV------------------ATWSLFCQMANWFIF 163
R + + + + +YL ++ TW L + ++ +
Sbjct: 97 RGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLM 156
Query: 164 FCLNRTFSN-CLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLV----IAALACAIRPTSA 218
F RT N + LT + L W + + ++ +V ++AL+ I S
Sbjct: 157 FYSTRTLPNFVMTLPLTNVAL-GWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFS- 214
Query: 219 VIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGF----TCLLDRLMYGSWVIVPLNFLK 274
VI+ + + + I G LG + +D + W + ++
Sbjct: 215 VIFKKISLFD--------------AIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFL 260
Query: 275 FNFLSSGGDYYGTHPWHWYFTQGFLVMLF-----TFTPFSIAGIIKSKNQKLSALILWVL 329
FN ++ +G P YFT +L M+F + + +K + +S L+ +
Sbjct: 261 FNVVAGYASKWGVEPVTAYFTH-YLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHI 319
Query: 330 AIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVS 364
+ S HKE+RF++ +P ++ A + +
Sbjct: 320 IVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLWEN 354
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
Length = 830
Score = 138 bits (345), Expect = 3e-31
Identities = 51/279 (18%), Positives = 89/279 (31%), Gaps = 60/279 (21%)
Query: 198 VNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLT-----------PNKVKFIILEVIP 245
+ + +A RPT + + L ++ L +P
Sbjct: 222 LQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALP 281
Query: 246 IGSLVLGFTCLLDRLMYGS---------------WVIVPLNFLKFNFLSSGGDYYGTHPW 290
L D L Y +V P NF+K N S+ +G HP
Sbjct: 282 ALVLF----IFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPC 337
Query: 291 HWY--------FTQGFLVMLFTFTPFSI------AGIIKSKNQKLSAL---ILWVLAIYS 333
+ + F L L F + ++ +S + I L S
Sbjct: 338 YVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLS 397
Query: 334 ILGHKEFRFVLPV-LPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRL 392
++ H+E RF+LPV P+ L+ + ++G S+ K + R + K
Sbjct: 398 LINHQEPRFLLPVTFPLILLHAPK-----LITGFSAKYPFQKDHPLLRLFYDKLLSSKAS 452
Query: 393 SVYFL---LATNIPMALYMSLFHQRGTEDAMNYLSDEAY 428
Y L +N+ + L+ HQ G +D ++
Sbjct: 453 GPYLLKIWYVSNVALTLFFGFIHQAG---VYPLAADISH 488
Score = 56.0 bits (134), Expect = 2e-06
Identities = 41/156 (26%), Positives = 61/156 (38%), Gaps = 18/156 (11%)
Query: 44 FCL-AFRVVNALLIQT-YFNPDEHWQSLEVAHRTIFGYGY-MTWEWKRGIRSYLHPMLFA 100
FC A R++ + Q Y +PDE +QS+EV F + TWE+ + + FA
Sbjct: 21 FCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFA 80
Query: 101 FLYKLLQV-------------TGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGN 147
L L Y + PRL+ ++ S D L++ LYG
Sbjct: 81 LLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLR 139
Query: 148 VATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGL 183
L ++W + RTFSN LE + L
Sbjct: 140 FE-IRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLL 174
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
Length = 197
Score = 135 bits (338), Expect = 2e-30
Identities = 41/210 (19%), Positives = 82/210 (38%), Gaps = 20/210 (9%)
Query: 145 GGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGL 204
G + A + + + ++R SN + T S+ N +
Sbjct: 1 GTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIAT---------NHSLSLLLKNNYYGSI 51
Query: 205 VIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYG 263
I A AI R A++ + + + L + ++L I +G + L+D +G
Sbjct: 52 SILVFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWG 111
Query: 264 SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSA 323
+W L FN + +GT P+++YF + + + F + + +
Sbjct: 112 AWCWPELEAFLFNVVEGKSSDWGTSPFYYYF----VRLPWLFLNPTTLLFLLISFVYIKP 167
Query: 324 ------LILWVLAIYSILGHKEFRFVLPVL 347
+ L+ + +YS LGHKE+RF++ +
Sbjct: 168 ARLLIYVPLFFIFVYSFLGHKEWRFIIYSI 197
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
Length = 457
Score = 121 bits (303), Expect = 3e-26
Identities = 49/241 (20%), Positives = 76/241 (31%), Gaps = 52/241 (21%)
Query: 150 TWSLFCQMA-NWFIFFCLNRTFSNCLETVLTIMGLYY------WPCIRDSSIDYPVNRKW 202
W+ ++ ++ RTFSN +E +L L W R P R W
Sbjct: 33 RWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSW 92
Query: 203 GLV----------IAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLG 252
L LA A+ P +W G L + L ++P +L
Sbjct: 93 LLGGIVAAGFFNRPTFLAFAVVP--LYLWGTRGATNPGLKSLTRE--ALVLLPGATLTAA 148
Query: 253 FTCLLDRLMY------GSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYF-TQGFL------ 299
D + + V+ P+NFL +N +GTH + GFL
Sbjct: 149 VFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLH 208
Query: 300 ------------VMLFTFTPFSIAGIIKSKNQ------KLSALILWVLAIYSILGHKEFR 341
V L + + +++ L L LA+ S H+E R
Sbjct: 209 AQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEAR 268
Query: 342 F 342
F
Sbjct: 269 F 269
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
Length = 283
Score = 117 bits (291), Expect = 6e-25
Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 29/144 (20%)
Query: 275 FNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWV----LA 330
FN + G +G HPW+WY G +L I G++ + S L + +
Sbjct: 131 FNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYII 190
Query: 331 IYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKL 390
++S+L HKE RF+LP++P+ I++G AF QN KW
Sbjct: 191 VHSLLPHKEQRFLLPIIPLLCIYAGGAF----------------------QNLKKWRG-- 226
Query: 391 RLSVYFLLATNIPMALYMSLFHQR 414
++ ++A NI +AL+ S +HQ+
Sbjct: 227 -SAMAVMIAINIGIALFTSRYHQK 249
Score = 88.7 bits (218), Expect = 2e-16
Identities = 27/68 (39%), Positives = 45/68 (65%)
Query: 34 RIGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSY 93
R+ + R+ + FR ++ L+ ++F PDE +QS EVAH ++G G+++WEW+ +RS+
Sbjct: 64 RMRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSF 123
Query: 94 LHPMLFAF 101
HP L AF
Sbjct: 124 FHPALIAF 131
>gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protein MGC3136 [Mus musculus]
Length = 385
Score = 115 bits (288), Expect = 1e-24
Identities = 44/232 (18%), Positives = 77/232 (32%), Gaps = 39/232 (16%)
Query: 40 RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGY------------GYMTWEWK 87
L L L+I Y +E + L+ H ++ G +
Sbjct: 12 WPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHHEFPGVVP---- 66
Query: 88 RGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDAL 143
R++L P++ A + +L + + Y R + + G L K
Sbjct: 67 ---RTFLGPLVIAAFSSPVVYVLSLLEVSKFYS-QLIVRGVLGLGVISGLWTLQKEVRQQ 122
Query: 144 YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWG 203
+G VA + + + F RT N L + + L W + R+W
Sbjct: 123 FGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAW-----------LQRRWA 171
Query: 204 LVI---AALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLG 252
L + A + R A++ +L L+ V ++ IP G L LG
Sbjct: 172 LFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLG 223
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
[Caenorhabditis elegans]
Length = 232
Score = 111 bits (277), Expect = 3e-23
Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 29/144 (20%)
Query: 275 FNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWV----LA 330
FN + G +G HPW+WY G +L I G++ + S L + +
Sbjct: 67 FNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYII 126
Query: 331 IYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKL 390
++S+L HKE RF+LP++P+ I++G AF QN KW
Sbjct: 127 VHSLLPHKEQRFLLPIIPLLCIYAGGAF----------------------QNLKKWRG-- 162
Query: 391 RLSVYFLLATNIPMALYMSLFHQR 414
++ ++A NI +AL+ S +HQ+
Sbjct: 163 -SAMAVMIAINIGIALFTSRYHQK 185
Score = 84.0 bits (206), Expect = 5e-15
Identities = 26/67 (38%), Positives = 44/67 (64%)
Query: 35 IGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYL 94
+ + R+ + FR ++ L+ ++F PDE +QS EVAH ++G G+++WEW+ +RS+
Sbjct: 1 MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFF 60
Query: 95 HPMLFAF 101
HP L AF
Sbjct: 61 HPALIAF 67
>ref|NP_276829.1| (NC_000916) unknown [Methanothermobacter thermautotrophicus]
pir||G69096 hypothetical protein MTH1717 - Methanobacterium thermoautotrophicum
(strain Delta H)
gb|AAB86189.1| (AE000928) unknown [Methanothermobacter thermautotrophicus]
Length = 557
Score = 43.5 bits (102), Expect = 0.009
Identities = 48/341 (14%), Positives = 104/341 (30%), Gaps = 47/341 (13%)
Query: 89 GIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNV 148
G+++Y +P LF + L + +P L + L +YK++ +
Sbjct: 67 GLKAYAYPPLFHVMGYGLYLLFRSELVFFFISPLLGTATV-----LVIYKVARETFEREE 121
Query: 149 ATWSLFCQMANWFIFFCLNRTF-SNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIA 207
+ F F + +LT LY ++ YP K+ L
Sbjct: 122 VALLSAFLFSMVPSFVARTSVFIPESMGLLLTSGILYMLVKYLKTTPGYPDIDKFEL--K 179
Query: 208 ALACAIRPTSAVIWLYVGMLELFLTPNK-VKFIILEVIPIGSLVLGFTC----------- 255
A + R I + + ++L ++ F+++ ++ + L +
Sbjct: 180 AFSNLFRGDLRYILGGLALFVIYLFTHRGWVFLLIALLLLAVTFLTPSFRKRPLEFGLIF 239
Query: 256 ------LLDRL-MYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPF 308
+++ + + VP+ L F P Q L +
Sbjct: 240 LLIGAGIIEFITFAARFQSVPVTILGF-------------PKWMGVLQLILGIYGASLLL 286
Query: 309 SIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSS 368
I + + A ++ YS FR +P++ + GYAF++++ +
Sbjct: 287 RSKNPIH-RFLIIWATAFMIIGTYSF----RFRDPYAAIPLS-LMGGYAFSEVKGR-LYA 339
Query: 369 SSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMS 409
S + R + + + Y
Sbjct: 340 SKRFKSYSIMKRDVKPFLRTGIFALLVLMPLAQGAAIAYTG 380
>ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
pir||S75173 hypothetical protein sll1946 - Synechocystis sp. (strain PCC 6803)
dbj|BAA17087.1| (D90903) ORF_ID:sll1946~unknown protein [Synechocystis sp. PCC
6803]
Length = 825
Score = 40.0 bits (93), Expect = 0.11
Identities = 51/359 (14%), Positives = 108/359 (29%), Gaps = 43/359 (11%)
Query: 44 FCLAFRVVNA-LLIQTYFNPDEHWQSLEVAHRTIFGYGYMT-----------WEWKRGIR 91
LA + + L + + D+ + + ++ +G Y+ W +
Sbjct: 14 LLLAMVWLGSNGLDRLWLGMDQTVPAWDQSNHLSYGLEYLQALRSPEFLSGEWWRSFWML 73
Query: 92 SYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW 151
S +P L + Q G + + + ++S I L +Y L L+ + W
Sbjct: 74 SPKYPPLTYIVNAPFQGLGGPGSDLALLS----NWLWSGILILSVYGLGKKLFSREIGLW 129
Query: 152 SLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALAC 211
++ + + + T++ +++ W +
Sbjct: 130 AVAIMVLIPRLIHSRLIVLLDSPLLAFTLLSFTCLTYWKEAE-GRRSQWLWAIAAGVGLG 188
Query: 212 AIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLV-LGFTCLLDRLMYG-SWVIVP 269
+ I Y+ + L + LV L + L Y +W+ +
Sbjct: 189 LGLLSKQSIIFYLFFPLVGLG-LWSIWTKQWQRLAQLLVGLLASIPLWYPWYRTNWIYLF 247
Query: 270 LNFLKFN----FLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALI 325
N L W +Y+ + + + + G+I S + A +
Sbjct: 248 STAQNSNAIPATLEGDPPVNTLAAWTYYWQDLPNALSWVWLIPPLVGVILSLLNRFPASL 307
Query: 326 -----------LWVLAIY--------SILGHKEFRFVLPVLPIALIFSGYAFAQMEVSG 365
L L Y S + +K+ R++LP LPI IF + +
Sbjct: 308 QIPSWREAKPGLLWLGYYYGGTYLICSAIQNKDDRYILPYLPIVAIFLAFGLTRWCGRW 366
>ref|NP_485359.1| (NC_003272) unknown protein [Nostoc sp. PCC 7120]
dbj|BAB73273.1| (AP003585) ORF_ID:all1316~unknown protein [Nostoc sp. PCC 7120]
Length = 523
Score = 40.0 bits (93), Expect = 0.12
Identities = 39/242 (16%), Positives = 85/242 (35%), Gaps = 23/242 (9%)
Query: 93 YLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW- 151
Y+ P ++ L L + + R + ++ S I +Y L L+ +
Sbjct: 96 YVFPPIYPVLTILWSYLFNNWFDNGLVIQRSLAALLSVIAIWAIYWLGLELFVSKTTAFV 155
Query: 152 -SLFCQMANWFIFFCL-NRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAAL 209
++ ++ + + + R +S + T + G ++ W + L
Sbjct: 156 AAVIVAISPFHLQYAQIIRPYSILIATTVIACGCLL------KAMHLKNLWWWLIY--GL 207
Query: 210 ACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVP 269
+ I S +++ +V + L+ + LVLG + L + W+
Sbjct: 208 SIVIGLYSNLLFAFVLVAHTVYVLINESLRNLKSLTAYFLVLGISTLA----FLPWLWAF 263
Query: 270 LN--FLKFNF--LSSGGDYYGT-HPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSAL 324
+N LK++ +S +G + W FL + PF +K+ + +
Sbjct: 264 INSSMLKYSVEQVSDKSSLFGLINAWLKGIQNLFLD---LYHPFFSPNFLKAAQWFFTPI 320
Query: 325 IL 326
IL
Sbjct: 321 IL 322
CPU time: 160.58 user secs. 3.00 sys. secs 163.58 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.317 0.176 0.495
Gapped
Lambda K H
0.270 0.0617 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 379711996
Number of Sequences: 887402
Number of extensions: 20590159
Number of successful extensions: 90718
Number of sequences better than 10.0: 726
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 689
Number of HSP's that attempted gapping in prelim test: 89569
Number of HSP's gapped (non-prelim): 1373
length of query: 548
length of database: 277,845,442
effective HSP length: 52
effective length of query: 496
effective length of database: 231,700,538
effective search space: 114923466848
effective search space used: 114923466848
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 76 (33.6 bits)