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GPI Anchor Biosynthesis Report: AAK91470.1 (PIG-B family, Arabidopsis thaliana)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query=
         (548 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Converged !!!


Results of PSI-Blast iteration 2

Distribution of 52 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)

ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 701 0.0
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 619 e-176
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 541 e-152
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 526 e-148
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 523 e-147
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 475 e-133
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 446 e-124
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 417 e-115
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 398 e-109
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 396 e-109
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 394 e-108
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 393 e-108
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 385 e-106
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 351 2e-95
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 343 3e-93
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 323 7e-87
gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan ... 309 7e-83
gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melano... 287 3e-76
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 274 2e-72
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 262 1e-68
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 259 1e-67
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 251 2e-65
emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus mus... 249 9e-65
ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo ... 247 2e-64
emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-... 247 4e-64
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 239 7e-62
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 237 5e-61
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 232 1e-59
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 226 6e-58
ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans] ... 216 8e-55
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 215 1e-54
pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans 210 7e-53
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 209 7e-53
pir||T39659 cell wall biosynthesis protein N3265 homolog - fissi... 202 1e-50
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 168 3e-40
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 167 4e-40
ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Sacch... 161 2e-38
gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 138 3e-31
dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharom... 135 2e-30
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 121 3e-26
pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans 117 6e-25
gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protei... 115 1e-24
ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]... 111 3e-23
Sequences with E-value WORSE than threshold

ref|NP_276829.1| (NC_000916) unknown [Methanothermobacter therma... 43 0.009
ref|NP_485359.1| (NC_003272) unknown protein [Nostoc sp. PCC 712... 40 0.12
Alignments
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase -like protein [Arabidopsis
           thaliana]
 gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
          Length = 548

 Score =  701 bits (1792), Expect = 0.0
 Identities = 548/548 (100%), Positives = 548/548 (100%)

Query: 1   MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
           MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF
Sbjct: 1   MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60

Query: 61  NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
           NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA
Sbjct: 61  NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120

Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
           PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI
Sbjct: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
           MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII
Sbjct: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240

Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
           LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV
Sbjct: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300

Query: 301 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 360
           MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ
Sbjct: 301 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 360

Query: 361 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 420
           MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM
Sbjct: 361 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 420

Query: 421 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 480
           NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP
Sbjct: 421 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 480

Query: 481 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVV 540
           LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVV
Sbjct: 481 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVV 540

Query: 541 YVVNHAFP 548
           YVVNHAFP
Sbjct: 541 YVVNHAFP 548
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein - Arabidopsis
           thaliana
 emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
           alpha-mannosyltransferase-like protein [Arabidopsis
           thaliana]
          Length = 498

 Score =  619 bits (1580), Expect = e-176
 Identities = 496/519 (95%), Positives = 496/519 (95%), Gaps = 23/519 (4%)

Query: 1   MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
           MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF
Sbjct: 1   MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60

Query: 61  NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
           NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA
Sbjct: 61  NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120

Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
           PRLMQSIFSAIGDLYLYKLSDALYGGNVATWS                       TVLTI
Sbjct: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWS-----------------------TVLTI 157

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
           MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII
Sbjct: 158 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 217

Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
           LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV
Sbjct: 218 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 277

Query: 301 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 360
           MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ
Sbjct: 278 MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQ 337

Query: 361 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 420
           MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM
Sbjct: 338 MEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAM 397

Query: 421 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 480
           NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP
Sbjct: 398 NYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESDQFLVNP 457

Query: 481 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKE 519
           LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKE
Sbjct: 458 LGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKE 496
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
           GPI-anchor biosynthesis [Mus musculus]
 dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
          Length = 542

 Score =  541 bits (1381), Expect = e-152
 Identities = 201/548 (36%), Positives = 308/548 (55%), Gaps = 47/548 (8%)

Query: 1   MDIRKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYF 60
           M +R+RK              V+  ++     G +G    + LF +A R++N  L+QT F
Sbjct: 22  MKLRRRK----------SRQYVSAQEKRSPRRGLLGENTYLVLFTIALRILNCFLVQTSF 71

Query: 61  NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
            PDE+WQSLEVAHR +F YGY+TWEW   +R Y +P++FA +YK+L + G D+   +I  
Sbjct: 72  VPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIFASIYKVLHLLGKDSVQFLIWI 131

Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
           PRL Q++ SA+ D+ LY L   L    VA W   CQ+ +WF ++C  RT +N +ET LT 
Sbjct: 132 PRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCSWFTWYCCTRTLTNTMETSLTA 191

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
           + L+Y+P     S++   + K+ L++A LAC +RPT+ + W+ +     +    K+   +
Sbjct: 192 LALFYYPLEGSRSVN---SIKYSLLVA-LACVVRPTALIPWVPLLFRHFYQEQRKLHLTL 247

Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
              +P+G +    + ++DR+ +G W +V LNFLKFN L + G +YG+HPWHWY +QGF V
Sbjct: 248 HHFLPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVLQNLGTFYGSHPWHWYLSQGFPV 307

Query: 301 MLFTFTPFSIAG--IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
           +L T  PF I G  +   +   L   +LW L +YS+LGHKEFRF+ PVLP  ++F GY+ 
Sbjct: 308 VLGTHLPFFIHGCFLAPRRLHILLLTVLWTLLVYSMLGHKEFRFIYPVLPFCMVFCGYSL 367

Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
           A ++                       W    + ++ FLL +N+P+A Y  L HQRGT D
Sbjct: 368 AHLKT----------------------WR---KAALSFLLLSNVPLAFYTGLVHQRGTLD 402

Query: 419 AMNYLSDEAYKGRV---KSILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDES 473
            MN++     +G      S+  +MPCHSTPYYS +H  + M+FL C P  + +   LDE+
Sbjct: 403 VMNHIQKVCPRGPDPASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKTQYLDEA 462

Query: 474 DQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRD 533
           D F +NPL +  +   + +  P+H+V F   E ++  F+   +++    FFH H+   R 
Sbjct: 463 DMFYLNPLRWLQQEFHSNASLPTHLVTFNVLEKEINTFLTSGNYERAATFFHTHWPE-RR 521

Query: 534 LQSSVVVY 541
             S + VY
Sbjct: 522 TGSHIHVY 529
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
          Length = 554

 Score =  526 bits (1342), Expect = e-148
 Identities = 205/548 (37%), Positives = 310/548 (56%), Gaps = 48/548 (8%)

Query: 2   DIRKRKNAGGDGDGGADGASVNVGDEPDSFGG-RIGSPRRIFLFCLAFRVVNALLIQTYF 60
            +RKRK               N  ++     G  +G    + LF LA R++N  L+QT F
Sbjct: 33  KLRKRK----------STLYFNTQEKSARRRGDLLGENIYLLLFTLALRILNCFLVQTSF 82

Query: 61  NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
            PDE+WQSLEV+H  +F YGY+TWEW   +RSY +P++FA +YK+L + G D+  ++I  
Sbjct: 83  VPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWI 142

Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
           PRL Q++ SA+ D+ LY L   L    VA W  FCQ+ +WF ++C  RT +N +ETVLTI
Sbjct: 143 PRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTI 202

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
           + L+Y+P     S++   + K+  ++A LA  IRPT+ ++W  +        P K+  I+
Sbjct: 203 IALFYYPLEGSKSMN---SVKYSSLVA-LAFIIRPTAVILWTPLLFRHFCQEPRKLDLIL 258

Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
              +P+G + L  + ++DR+ +G W +V  NFLKFN L + G +YG+HPWHWYF+QGF V
Sbjct: 259 HHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNLGTFYGSHPWHWYFSQGFPV 318

Query: 301 MLFTFTPFSIAG--IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
           +L T  PF I G  +   + + L   +LW L +YS+L HKEFRF+ PVLP  ++F GY+ 
Sbjct: 319 ILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSL 378

Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
             ++                            + ++ FL  +N+ +ALY  L HQRGT D
Sbjct: 379 THLK-------------------------TWKKPALSFLFLSNLFLALYTGLVHQRGTLD 413

Query: 419 AMNYLSDEAYKGRVK---SILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDES 473
            M+++    Y    K   SI  +MPCHSTPYYS +H  +PM+FL C P  + +   LDE+
Sbjct: 414 VMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEA 473

Query: 474 DQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRD 533
           D F +NPL ++     + +  P+H++ F+  E ++  F+I  ++K    FFH H    R 
Sbjct: 474 DVFYLNPLNWSHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGR- 532

Query: 534 LQSSVVVY 541
           + S + VY
Sbjct: 533 IGSHIYVY 540
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
 pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
           (EC 2.4.1.130) PIGB - human
 dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
          Length = 554

 Score =  523 bits (1335), Expect = e-147
 Identities = 204/548 (37%), Positives = 309/548 (56%), Gaps = 48/548 (8%)

Query: 2   DIRKRKNAGGDGDGGADGASVNVGDEPDSFGG-RIGSPRRIFLFCLAFRVVNALLIQTYF 60
            +RKRK               N  ++     G  +G    + LF +A R++N  L+QT F
Sbjct: 33  KLRKRK----------STLYFNTQEKSARRRGDLLGENIYLLLFTIALRILNCFLVQTSF 82

Query: 61  NPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKA 120
            PDE+WQSLEV+H  +F YGY+TWEW   +RSY +P++FA +YK+L + G D+  ++I  
Sbjct: 83  VPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLIFASIYKILHLLGKDSVQLLIWI 142

Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
           PRL Q++ SA+ D+ LY L   L    VA W  FCQ+ +WF ++C  RT +N +ETVLTI
Sbjct: 143 PRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLCSWFTWYCCTRTLTNTMETVLTI 202

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFII 240
           + L+Y+P     S++   + K+  ++A LA  IRPT+ ++W  +        P K+  I+
Sbjct: 203 IALFYYPLEGSKSMN---SVKYSSLVA-LAFIIRPTAVILWTPLLFRHFCQEPRKLDLIL 258

Query: 241 LEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLV 300
              +P+G + L  + ++DR+ +G W +V  NFLKFN L + G +YG+HPWHWYF+QGF V
Sbjct: 259 HHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNWGTFYGSHPWHWYFSQGFPV 318

Query: 301 MLFTFTPFSIAG--IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
           +L T  PF I G  +   + + L   +LW L +YS+L HKEFRF+ PVLP  ++F GY+ 
Sbjct: 319 ILGTHLPFFIHGCYLAPKRYRILLVTVLWTLLVYSMLSHKEFRFIYPVLPFCMVFCGYSL 378

Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
             ++                            + ++ FL  +N+ +ALY  L HQRGT D
Sbjct: 379 THLK-------------------------TWKKPALSFLFLSNLFLALYTGLVHQRGTLD 413

Query: 419 AMNYLSDEAYKGRVK---SILFLMPCHSTPYYSTLHRNIPMQFLDCTP--SAEKGELDES 473
            M+++    Y    K   SI  +MPCHSTPYYS +H  +PM+FL C P  + +   LDE+
Sbjct: 414 VMSHIQKVCYNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGKSHYLDEA 473

Query: 474 DQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHAHFKVDRD 533
           D F +NPL +      + +  P+H++ F+  E ++  F+I  ++K    FFH H    R 
Sbjct: 474 DVFYLNPLNWLHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFFHTHLPEGR- 532

Query: 534 LQSSVVVY 541
           + S + VY
Sbjct: 533 IGSHIYVY 540
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
 dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
           sativa]
          Length = 506

 Score =  475 bits (1211), Expect = e-133
 Identities = 289/544 (53%), Positives = 365/544 (66%), Gaps = 63/544 (11%)

Query: 1   MDIRKRKNAG-----GDGDGGADGASVNVGDEPD--SFGGRIGSPRRIFLFCLAFRVVNA 53
           M  R+R+NA          G +   + + G+E     +   +GS RR+    LAFR  NA
Sbjct: 1   MSHRRRRNAAGPPPPEGIGGSSTAEASSTGEERPDLPWAWALGSERRVLALALAFRAANA 60

Query: 54  LLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDT 113
           LL++TYFNPDEHWQ LEVAHR +FGYG++TWEWKRG+RSYLHP +FA LYK+L +  LD+
Sbjct: 61  LLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFAALYKILSLLHLDS 120

Query: 114 PYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNC 173
           P+ M  APRL+QS+F++ GDLYLYKLS  ++  +VA                        
Sbjct: 121 PWFMAMAPRLLQSVFASFGDLYLYKLSKLIFNNHVAH----------------------- 157

Query: 174 LETVLTIMGLYYWPCIRDS-------------SIDYPVNRKWGLVIAALACAIRPTSAVI 220
           +ETVLT+ GLYYW    +S             S   P +RK  L+IAALACAIRPTSA+ 
Sbjct: 158 METVLTVTGLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAIT 217

Query: 221 WLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSS 280
           WLYVG+L+     +K +FI LEV+P+G  VL  T  LD  MYGS +IVPLNFLKFN  SS
Sbjct: 218 WLYVGLLDFIQMKSKSRFIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSS 277

Query: 281 GGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEF 340
           GGDYYGTH +HWYF+QGF  M++TF PFSI+GI+KS+  +L+ LI+WVL +YSILGHKEF
Sbjct: 278 GGDYYGTHVFHWYFSQGFPSMIWTFLPFSISGILKSREWRLAGLIVWVLVVYSILGHKEF 337

Query: 341 RFVLPVLPIALIFSGY---AFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFL 397
           RFVLPVLP   +FSG+   A AQ++  G +                     +L+LSV  L
Sbjct: 338 RFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKG---------------RLSRLKLSVILL 382

Query: 398 LATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQ 457
           + TN+PMALYMSL+HQRGTEDAM YLS EA+ GRVKS+LFLMPCHSTPYYSTLH N+PM+
Sbjct: 383 ILTNVPMALYMSLYHQRGTEDAMLYLSREAHDGRVKSVLFLMPCHSTPYYSTLHYNLPMR 442

Query: 458 FLDCTPSAEKGELDESDQFLVNPLGFASELARNWSEPPSHIVLFASEETKLRDFMIQHSF 517
           FLDCTPS  KG LDESD+FL+NP  F  E+  N S   SHIVLF SEE  ++  ++++SF
Sbjct: 443 FLDCTPSENKGTLDESDRFLMNPADFVGEVFGNLSS-FSHIVLFESEERHVK-LLLRNSF 500

Query: 518 KEVR 521
           +EV+
Sbjct: 501 QEVK 504
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
          Length = 512

 Score =  446 bits (1136), Expect = e-124
 Identities = 176/518 (33%), Positives = 273/518 (51%), Gaps = 73/518 (14%)

Query: 40  RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLF 99
            +FL  LA R+ +  ++QTY+ PDE+WQSLEVAH+  FGYGY+TWEW +GIRSY++P+L 
Sbjct: 5   YVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLI 64

Query: 100 AFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMAN 159
           A LYK+L +  LD+ ++++  PR                         +  W+LF  +  
Sbjct: 65  AGLYKILALLQLDSAHLLVVLPR-------------------------IRKWALFLILVP 99

Query: 160 WFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAV 219
           WF F+  +RT +N LE  LT + L Y+P   +S+          L  AA+ C +RPT+AV
Sbjct: 100 WFWFYTGSRTLANTLEASLTTIALSYFPWYGESTA--------YLWPAAICCFLRPTAAV 151

Query: 220 IWLYVGMLELFL-TPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL 278
           IWL + +  L     N ++ I+   + IG LV G    +D   +G  ++ P  FLK+N  
Sbjct: 152 IWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIF 211

Query: 279 SSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIK--------SKNQKLSALILWVLA 330
           ++ G +YG+HPWHWYF+ G   +L   T   I G+++          +++L   I   L 
Sbjct: 212 NNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLV 271

Query: 331 IYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKL 390
           + S + HKEFRFV P+LP+ L     A ++  +  SS+                 W+  L
Sbjct: 272 VLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASST---------------MLWTTAL 316

Query: 391 RLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVK-----SILFLMPCHSTP 445
                 +L  N+  A Y+S  HQ+G  + M  L + A + R +     +ILFLMPCHSTP
Sbjct: 317 -----VILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTP 371

Query: 446 YYSTLHRNIPMQFLDCTPSAEKGEL--DESDQFLVNPLGFASEL--ARNWSEPPSHIVLF 501
           YYS +H+N+ M+FL C P+ EK E   DE+D+F  +P+ + +        +  P+H+VLF
Sbjct: 372 YYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLF 431

Query: 502 ASEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVV 539
                 +  F+   +++ + R  HA  +  R  +S +V
Sbjct: 432 DPLAENISVFL--RNYRLLHRIEHAENRQSRTGRSILV 467
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
           [Schizosaccharomyces pombe]
          Length = 506

 Score =  417 bits (1063), Expect = e-115
 Identities = 164/536 (30%), Positives = 260/536 (47%), Gaps = 70/536 (13%)

Query: 40  RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLF 99
             +L  L FR  NAL ++T+F PDE +QSLEVAH  IF YG++TWEW   IRS LHP++F
Sbjct: 4   WFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHPLIF 63

Query: 100 AFLYKLLQVTGLDTPYIMIK-APRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMA 158
           A LY++LQV  LD+ Y +   AP+L+Q  F+AI D   YK +   YG   A W+L C + 
Sbjct: 64  AALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKTANWTLACSLV 123

Query: 159 NWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWG-------LVIAALAC 211
           +    +   RTFSN LET LT +G YY+          P  RK         + +AA AC
Sbjct: 124 SIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAFAC 183

Query: 212 AIRPTSAVIWLYVGMLE-------------LFLTPNKVKFI-------ILEVIPIGSLVL 251
            IRPT+ ++W++  +                    N+ +F+       +  +  +   + 
Sbjct: 184 FIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVSLF 243

Query: 252 GFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIA 311
               + DR++YG +V   ++F +FN  S     YG + WH+Y +Q   ++   F PF   
Sbjct: 244 LVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPF--- 300

Query: 312 GIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSS 371
            ++ + + + +  IL V   YS++GHKE RFV P+ PI L  +G  F           SS
Sbjct: 301 -VLLTMDLQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFF-----------SS 348

Query: 372 VTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMAL-YMSLFHQRGTEDAMNYLSDEAYKG 430
            +  K+  R              +FL+     + + ++  FHQ G  + M  +   A K 
Sbjct: 349 FSSWKRAAR-------------FFFLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKN 395

Query: 431 RVKSILFLMPCHSTPYYSTLHRNIP---MQFLDCTPSAEKGELDESDQFLVNPLGFASEL 487
           +    L L PCH+TP+ S +H        +FL C P  +    DE+D+F  N   F  ++
Sbjct: 396 QTG--LILAPCHTTPWQSHIHSPFAENGWKFLTCEPFEKP--FDETDRFYENMPTFLDKI 451

Query: 488 ARNWSEPPSHIVLFASEETKLRDFMIQHS--FKEVRRFFHAHFKVDRDLQSSVVVY 541
                E P +++ F      L  ++      ++EV+R++++     R+   +++VY
Sbjct: 452 ----KEWPDYLIFFEERFYSLYSYLDSRGLKYEEVQRYYNSLIPESRERAGALLVY 503
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
          Length = 611

 Score =  398 bits (1014), Expect = e-109
 Identities = 106/458 (23%), Positives = 179/458 (38%), Gaps = 55/458 (12%)

Query: 6   RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
           R+  G    GGA+  +   G++     G++ +P     F CL    + A L+    + DE
Sbjct: 28  RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83

Query: 65  HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
            +   E  H  I+G G+ TWE+     IRSY    LH    AF  ++LQ   +   Y + 
Sbjct: 84  TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142

Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
              R + +  S I +LY YK     +G +V+   L   + +    FC +  F   S C+ 
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198

Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
           T L  M  +Y      + +           +AA A    P SA + L +   +L +  ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247

Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYF 294
            K      +    L L    ++D   YG  VI PLN + +N     G D YGT PW++Y 
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYL 307

Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
             GFL                  M +    F +  +       L+ + +W +  + I  H
Sbjct: 308 INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366

Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFL 397
           KE RF+ PV P+  +    A + ++           + +       + W     + ++ L
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQKCYH---FVFQRYRLEHYTVTSNWLALGTVFLFGL 423

Query: 398 LATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
           L+ +  +AL+       G  D        A    + ++
Sbjct: 424 LSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 458
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
          Length = 611

 Score =  396 bits (1008), Expect = e-109
 Identities = 106/458 (23%), Positives = 180/458 (39%), Gaps = 55/458 (12%)

Query: 6   RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
           R+  G    GGA+  +   G++     G++ +P     F CL    + A L+    + DE
Sbjct: 28  RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83

Query: 65  HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
            +   E  H  I+G G+ TWE+     IRSY    LH    AF  ++LQ   +   Y + 
Sbjct: 84  TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142

Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
              R + +  S I +LY YK     +G +V+   L   + +    FC +  F   S C+ 
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198

Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
           T L  M  +Y      + +           +AA A    P SA + L +   +L +  ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247

Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYF 294
            K      +    L L    ++D   YG  VI PLN + +N     G D YGT PW++Y 
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYL 307

Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
            +GFL                  M +    F +  +       L+ + +W +  + I  H
Sbjct: 308 IKGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366

Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFL 397
           KE RF+ PV P+  +    A + ++           + +       + W     + ++ L
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQKCYH---FVFQRYRLEHYTVTSNWLALGTVFLFGL 423

Query: 398 LATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
           L+ +  +AL+       G  D        A    + ++
Sbjct: 424 LSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 458
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
          Length = 618

 Score =  394 bits (1002), Expect = e-108
 Identities = 107/462 (23%), Positives = 180/462 (38%), Gaps = 56/462 (12%)

Query: 6   RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
           R+  G    GGA+  +   G++     G++ +P     F CL    + A L+    + DE
Sbjct: 28  RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83

Query: 65  HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
            +   E  H  I+G G+ TWE+     IRSY    LH    AF  ++LQ   +   Y + 
Sbjct: 84  TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142

Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
              R + +  S I +LY YK     +G +V+   L   + +    FC +  F   S C+ 
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198

Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
           T L  M  +Y      + +           +AA A    P SA + L +   +L +  ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247

Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYF 294
            K      +    L L    ++D   YG  VI PLN + +N     G D YGT PW++Y 
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDLYGTEPWYFYL 307

Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
             GFL                  M +    F +  +       L+ + +W +  + I  H
Sbjct: 308 INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366

Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSS----SSVTKKKQVPRQNHTKWSPKLRLS 393
           KE RF+ PV P+  +    A + ++ S             + +       + W     + 
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVF 426

Query: 394 VYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
           ++ LL+ +  +AL+       G  D        A    + ++
Sbjct: 427 LFGLLSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 465
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
           mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
 dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
          Length = 618

 Score =  393 bits (1000), Expect = e-108
 Identities = 108/462 (23%), Positives = 181/462 (38%), Gaps = 56/462 (12%)

Query: 6   RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
           R+  G    GGA+  +   G++     G++ +P     F CL    + A L+    + DE
Sbjct: 28  RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83

Query: 65  HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
            +   E  H  I+G G+ TWE+     IRSY    LH    AF  ++LQ   +   Y + 
Sbjct: 84  TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142

Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNCLE 175
              R + +  S I +LY YK     +G +V+   L   + +    FC +  F   S C+ 
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFCMY 198

Query: 176 TVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNK 235
           T L  M  +Y      + +           +AA A    P SA + L +   +L +  ++
Sbjct: 199 TTLIAMTGWYMDKTSIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLVMKHR 247

Query: 236 VKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFN-FLSSGGDYYGTHPWHWYF 294
            K      +    L L    ++D   YG  VI PLN + +N F   G D YGT PW++Y 
Sbjct: 248 WKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNIFTPHGPDLYGTEPWYFYL 307

Query: 295 TQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGH 337
             GFL                  M +    F +  +       L+ + +W +  + I  H
Sbjct: 308 INGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQPH 366

Query: 338 KEFRFVLPVLPIALIFSGYAFAQMEVSGSSSS----SSVTKKKQVPRQNHTKWSPKLRLS 393
           KE RF+ PV P+  +    A + ++ S             + +       + W     + 
Sbjct: 367 KEERFLFPVYPLICLCGAVALSALQHSFLYFQKCYHFVFQRYRLEHYTVTSNWLALGTVF 426

Query: 394 VYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
           ++ LL+ +  +AL+       G  D        A    + ++
Sbjct: 427 LFGLLSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 465
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
           musculus]
          Length = 611

 Score =  385 bits (981), Expect = e-106
 Identities = 106/460 (23%), Positives = 180/460 (39%), Gaps = 55/460 (11%)

Query: 8   NAGGDGDGGADGASVNVGDEP----DSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNP 62
           +AG   +      S   G EP     +  G++ +P     F CL    + A L+    + 
Sbjct: 22  DAGPAAEKLEQLGSREAGAEPRPESGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDC 81

Query: 63  DEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYI 116
           DE +   E  H  I+G G+ TWE+     IRSY    LH    AF  ++LQ   +   Y 
Sbjct: 82  DETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVFYF 141

Query: 117 MIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTF---SNC 173
           +    R + +  S + +LY YK     +G +V+   L   + +    FC +  F   S C
Sbjct: 142 L----RCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSAFLPSSFC 196

Query: 174 LETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTP 233
           + T L  M  +Y      + +           +AA A    P SA + L +   +L    
Sbjct: 197 MYTTLIAMTGWYMDKTPIAVLG----------VAAGAILGWPFSAALGLPI-AFDLLARK 245

Query: 234 NKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHW 292
           ++ K  +L  +   +L L    ++D   YG  V+ PLN + +N   S G D YGT PW++
Sbjct: 246 HRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVLYNVFTSHGPDLYGTEPWYF 305

Query: 293 YFTQGFLV-----------------MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSIL 335
           Y   GFL                  M +    F +  +       L+ + +W +  + I 
Sbjct: 306 YLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFIIFF-IQ 364

Query: 336 GHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVY 395
            HKE RF+ PV P+  +    A + ++           + +       + W     + ++
Sbjct: 365 PHKEERFLFPVYPLICLCGAVALSALQKCYH---FVFQRYRLEHYTVTSNWLALGTVFLF 421

Query: 396 FLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSI 435
            LL+ +  +AL+       G  D        A    + ++
Sbjct: 422 GLLSFSRSVALFRGY---HGPLDLYPEFYRIATDPTIHTV 458
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
           could be the target of the GPI synthesis inhibitor,
           YW3548; Most likely an alpha 1,2 mannosyltransferase
           utilized for the addition of the third mannose onto the
           GPI core structure.; Gpi1>
 sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
 pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
 emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
          Length = 616

 Score =  351 bits (892), Expect = 2e-95
 Identities = 122/489 (24%), Positives = 214/489 (42%), Gaps = 84/489 (17%)

Query: 115 YIMIKAPRLMQSIFSAIGDLYLYKLSDALY------------------GGNVATWSLFCQ 156
           Y +I AP+++ ++ ++IG+ Y+ +    LY                     +  ++L   
Sbjct: 135 YGVIYAPKIVMAVLASIGEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFALLLS 194

Query: 157 MANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPT 216
           + N+F  F + RTF N  E +LT + LYYW       I    +    L+ A LAC  RP+
Sbjct: 195 LTNFFNCFFITRTFINSFEMILTSIALYYWDWTGGQMI-KESSFTKSLIFAFLACLQRPS 253

Query: 217 SAVIWLYVGMLELFLTPNKVKFIIL-----EVIPIGSLVLGFTCLLDRLMYGSWVIVPLN 271
           S +IW+   +  +     K ++ +L     +V+    LV     ++D   Y         
Sbjct: 254 SGLIWVIPSISLILNLVGKKQYHLLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPFFR 313

Query: 272 FLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK----------- 320
           FLKFNF +    +YG  PWH++F Q   ++L    P    G+    +++           
Sbjct: 314 FLKFNFTTPLSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFF 373

Query: 321 -LSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVP 379
            +   IL  L +YS L HKEFRF+ P+ P+ ++ S +   +++                 
Sbjct: 374 QVKLTILLNLLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLD----------------- 416

Query: 380 RQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLM 439
            +++ K    L+  ++ +   ++ +AL +  FH+ G+ + M +L +E     + S+ F+M
Sbjct: 417 -RDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVMKFLHEEP---EIDSLGFIM 472

Query: 440 PCHSTPYYSTLH-----------RNIPMQFLDCTPSAEKG--ELDESDQFLVN------- 479
           PCHSTP  S LH            N P+  L    +  K    +DESD    +       
Sbjct: 473 PCHSTPGQSYLHRSDIQDLWSITCNPPLHLLGDPEAYSKLETYMDESDHLYDDISAFIYK 532

Query: 480 --PLGFASEL---ARNWS-EPPSHIVLFASEETK-LRDFMIQHSFKEVRRFFHAHFKVDR 532
             P  F  +L    + +S E P+++V+F   E   L+DF+   S+ E  RFF++    D 
Sbjct: 533 NFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENAFLKDFLKDSSYIEYNRFFNSLAHWDS 592

Query: 533 DLQSSVVVY 541
                +++Y
Sbjct: 593 RRSGDIIIY 601
 Score = 88.7 bits (218), Expect = 2e-16
 Identities = 38/73 (52%), Positives = 52/73 (71%)

Query: 39  RRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPML 98
            +IF   LAFRV+NA+L +T+F  DE WQ+LE AH   F YG +TWEWK G+RSYL PM+
Sbjct: 15  TQIFWVFLAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYGELTWEWKFGVRSYLFPMI 74

Query: 99  FAFLYKLLQVTGL 111
           F   Y+L+ ++ +
Sbjct: 75  FELTYRLVSLSSI 87
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
 gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
 gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
          Length = 623

 Score =  343 bits (873), Expect = 3e-93
 Identities = 93/440 (21%), Positives = 160/440 (36%), Gaps = 39/440 (8%)

Query: 8   NAGGDGDGGADGASVNV--GDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYFNPDEH 65
            AG   D  A   +     G E       + S +  F   ++ R+ +A+      + DE 
Sbjct: 41  PAGKKKDKDAKKRNQPTSGGQEKGLPNPIMPSVQTAFKTFVSARLCSAIW-AYIADCDET 99

Query: 66  WQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRL 123
           +   E  H  I G+G  TWE+    G+RSY + +L        Q     +P ++    R 
Sbjct: 100 FNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQGVPGYFYQKLFNPSPILIFYMVRC 159

Query: 124 MQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGL 183
           M     A+ + Y+YK     +G ++    L  Q+ +  +F        +          L
Sbjct: 160 MLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFSVGMFVSSTALLPSSFSMYFGCAAL 219

Query: 184 YYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILE 242
             W         +  N  + + + A++  +  P +A+I + + + E+ L     K  +  
Sbjct: 220 AAW---------WQQNYCFAIFLTAISALLGWPFAALIGIPLVL-EMLLRQRDWKTFVQW 269

Query: 243 VIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFL-SSGGDYYGTHPWHWYFTQGFLV- 300
            +  G+ V      +D   +G     PLN + +N   S G + +GT P  +Y   GFL  
Sbjct: 270 TLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPNIFGTEPLSYYIINGFLNF 329

Query: 301 --MLFTFTPFSIAGIIK--------------SKNQKLSALILWVLAIYSILGHKEFRFVL 344
             +        I  +I                    L+ L LW+L  +    HKE RF+ 
Sbjct: 330 NIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISLAPLYLWLLVFF-AQPHKEERFLF 388

Query: 345 PVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQ-VPRQNHTKWSPKLRLSVYFLLATNIP 403
           P+ P+  +         +       S V K K  V   +H+ +   L +    LL  +  
Sbjct: 389 PIYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSMFIAILVMVTSTLLGLSRV 448

Query: 404 MALYMSLFHQRGTEDAMNYL 423
            ALY +        D M  L
Sbjct: 449 FALYRNY---HAPMDLMLEL 465
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
          Length = 558

 Score =  323 bits (820), Expect = 7e-87
 Identities = 124/480 (25%), Positives = 213/480 (43%), Gaps = 92/480 (19%)

Query: 38  PRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPM 97
           P  +      +R+     I+T   PDE WQS EVA+  +FG G++ WEW+ G+RS L P 
Sbjct: 2   PWWLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPA 61

Query: 98  LFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYK---------------LSDA 142
           + A  + LL++ G DT + +  APR++Q++   + D+ ++                L++ 
Sbjct: 62  VVALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDVSVFCMGATLDELLAKRELELAEE 121

Query: 143 LYGGNVATWSLFC----------------------QMANWFIFFCLNRTFSNCLETVLTI 180
                   +S FC                       ++NW++ +C  R + N +E +L +
Sbjct: 122 TRQSKTKGFSYFCEVSVSRSRRGICNSISYTALLLSLSNWYMAYCGVRLYGNVIEALLVL 181

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKF-- 238
           + L                    L++  LA AIR TSAV+   +    L     +  F  
Sbjct: 182 LTLQ------------QRRYVPFLLLTGLASAIRVTSAVVLSPLVFRHLANATREHGFIR 229

Query: 239 ----IILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYF 294
               I+L  + +   VLG   +LD   YG WV+ PL F +FN L +   ++G HPW++Y 
Sbjct: 230 GLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFFRFNVLHNLSRFFGEHPWYFYV 289

Query: 295 TQGFLVMLFTFTPFSIAGII----KSKNQKLSALIL-------WVLAIYSILGHKEFRFV 343
               + ++     F+IA  +     + ++ +S  +L       W L  YS++ HKE RFV
Sbjct: 290 GPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGMLGIGAWTLGFYSLIDHKEMRFV 349

Query: 344 LPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIP 403
             V+P++LI + +      V  S +S+ V K  +                ++ L   NI 
Sbjct: 350 FVVIPLSLITAAFVL----VRWSRTSAVVVKMNR----------------LFVL--FNIV 387

Query: 404 MALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIP-MQFLDCT 462
           M   M   ++RG  D M  + D     R+  +  +  C++ P YS +H+ +  + F+DC+
Sbjct: 388 MIYLMGYVYRRGPLDVMAEVRDGP---RINRLDVIATCYTVPGYSYMHKKVNHLGFVDCS 444
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
          Length = 509

 Score =  309 bits (785), Expect = 7e-83
 Identities = 85/432 (19%), Positives = 151/432 (34%), Gaps = 24/432 (5%)

Query: 41  IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFA 100
           I L  L  R+     I  Y++PDE +Q LE AHR  FGY  + WE++ G+R  L P+L A
Sbjct: 26  ITLLALCLRMTAIFPIG-YYHPDEIFQYLEQAHRLAFGYSVIPWEYRYGMRGGLVPVLLA 84

Query: 101 FLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANW 160
              K+  +    +  +    P  + ++ S       YKL   L+       ++F     +
Sbjct: 85  AAMKMGDIMNTQSF-LYWVLPHAITALLSLGVIWSAYKLG-RLHSFFTGCLAMFVAATWY 142

Query: 161 FIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVI 220
            I        S  L     +   YY            ++      +  L+  +R      
Sbjct: 143 EIVLFAAHPLSESLSFAAFMPAAYYLIAEEKKKSSLILSG----FLMGLSALLRFQYIPS 198

Query: 221 WLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSS 280
            L++ +  L +   +  + IL  +    +       +        + +  N  + N +  
Sbjct: 199 ILFITLFTLRINVRQWGYFILGGLGAVFISSLSDIFIGEY---PLLWLFKNI-QQNLIFH 254

Query: 281 GGDYYGTHPWHWYFTQGFLV-MLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKE 339
             + YGT P + YF   +     F+        +   +   L    L  L  + ++ HKE
Sbjct: 255 RAEDYGTAPIYSYFFDIWTNWKWFSLILPIPILVAAYRYPALFGTALVNLIFHMLVSHKE 314

Query: 340 FRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLA 399
           +RF+     I +I +    + + +  ++ + +   KK       T W         FL +
Sbjct: 315 YRFIFLSSGIFIILAAIG-SALLIEKATINFTPLHKKLAQIAAFTAWGA-----CSFLCS 368

Query: 400 TNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFL 459
           T      Y      RG   A       +        L+ +    +  YS LHR IP+  L
Sbjct: 369 TGNISHWY----QYRGVLQAEMKARSLS--NLCGLTLYQIDYWESGGYSLLHRPIPIYSL 422

Query: 460 DCTPSAEKGELD 471
             +        D
Sbjct: 423 LPSNMYSTRYPD 434
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
 gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
          Length = 678

 Score =  287 bits (729), Expect = 3e-76
 Identities = 66/372 (17%), Positives = 142/372 (37%), Gaps = 34/372 (9%)

Query: 67  QSLEVAHRTIFGYGYMTWEWKRGIRSYLHPM-------LFAFLYKLLQVTGLDTPYIMIK 119
            +        +  G +        R+++ P+        F  L++ L +      Y++  
Sbjct: 38  NNFTQYDHHDYP-GVVP-------RTFIGPLVVSIISAPFVLLFETLSINKFWAQYVV-- 87

Query: 120 APRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLT 179
             RL+ +   ++    L +    +YG  V  W     +  +   F + R   N     + 
Sbjct: 88  --RLVLAGAISVAWNSLRQAVTKIYGVEVRLWFTAITITQFHFMFYMTRPLPNIFALPIV 145

Query: 180 IMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKF 238
           +  + YW              K  ++ + ++  + R   A+    + ++ L      +  
Sbjct: 146 LFAIAYW---------LRDQHKPFIICSGISILVFRSELALFLGILLVVSLLRRKVSIDG 196

Query: 239 IILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGF 298
           ++   +P G  +L  T L+D   +   +      L +N + +    +GT P+ WYF    
Sbjct: 197 LLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYNTVLNKSSNWGTSPFLWYFYSAL 256

Query: 299 LVMLFTFTPFSIAGI-IKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYA 357
              +         G+ ++ + + L    L  + +YSIL HKE RF++ V P+  I +  A
Sbjct: 257 PRAMGASLVLVPIGVALEPRIRPLVLSALLFVLLYSILPHKELRFIIYVFPVLNIAAACA 316

Query: 358 FAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFH--QRG 415
             ++ ++  S+ S+      +    H   +  + L +  +  TN P    +S  H  + G
Sbjct: 317 CQRIWMN--SAKSTWHSFLALACGAHLLLNVFITLFLLVISGTNYPGGAALSRLHRLEAG 374

Query: 416 TEDAMNYLSDEA 427
           T +   ++S+ A
Sbjct: 375 TSNVSVHISNLA 386
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
          Length = 919

 Score =  274 bits (696), Expect = 2e-72
 Identities = 102/511 (19%), Positives = 169/511 (32%), Gaps = 52/511 (10%)

Query: 4   RKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFC----LAFRVVNALLIQTY 59
           R+R+    D    +   S +  D+P    G       +  F     L +    +      
Sbjct: 356 RQRRPLISDSSSSSSTKSYSKTDKPGRSNGGDAEDGGLRWFLPFIALCYLRYMSATSNII 415

Query: 60  FNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIM 117
            + DE +   E  H  ++  G+ TWE+     +RSYL+ +      +       D    +
Sbjct: 416 HDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFHELAGRPASWWFGDDKVRV 475

Query: 118 IKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETV 177
             A RL   + SA+ D  L       YG  +AT+++         FF       +     
Sbjct: 476 FYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLTSGCFFASTSFLPSSFSM- 534

Query: 178 LTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI---RPTSAVIWLYVGMLELFLTPN 234
                          S    +  K+ + +A     +    P S + +L V +  L +   
Sbjct: 535 ----------YAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSL-VKRF 583

Query: 235 KVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSG-GDYYGTHPWHWY 293
           K  FI   V  I  L  G + L+D   Y  W    LN L +N L  G    YGT    +Y
Sbjct: 584 KQAFIAGAVTTIFLL--GVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFY 641

Query: 294 F--------TQGFLVMLFTFTPFSIAGIIKSKNQ-KLSALILWVLAIYSILGHKEFRFVL 344
                        L MLF      I           +S + +W LA  S+  HKE RF+ 
Sbjct: 642 IRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW-LAFMSLQPHKEERFLY 700

Query: 345 PVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPM 404
           P+ P+  + +  A  +          S  +   V    + +    + L      + +   
Sbjct: 701 PIYPLICVSAS-AVIENIPELFREKYSSRESLLVTITKYMR---PVILGCILCASHSRTF 756

Query: 405 ALYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPS 464
           AL           +    L      G   S+L    C  + ++       P  F      
Sbjct: 757 ALINGY---SAPLEVYKLLEHHDDAGP-GSVL----CVGSEWHRY-----PSSFFVPHYI 803

Query: 465 AEKGELDESDQFLVNPLGFASELARNWSEPP 495
           +E   +D+  + L+ P  F + L    + PP
Sbjct: 804 SEVRWIDDGFRGLL-PFPFNNTLGGTSASPP 833
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
           lipid-linked oligosaccharides; Alg9p [Saccharomyces
           cerevisiae]
 sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
 pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
 emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
          Length = 555

 Score =  262 bits (664), Expect = 1e-68
 Identities = 65/326 (19%), Positives = 112/326 (33%), Gaps = 10/326 (3%)

Query: 41  IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPML 98
           + L     RV          + DE +   E  +  + G+G  TWE+     IRS+   + 
Sbjct: 10  LLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYSIRSWAFLLP 69

Query: 99  FAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMA 158
           F  +   +        +      R     FS I +  L++         +A   +  Q+ 
Sbjct: 70  FYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQIANIWIIFQLF 129

Query: 159 NWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSA 218
           N   F        + +  +L +    +   +R  S     N    L    LA  +     
Sbjct: 130 NPGWFHASVELLPSAVAMLLYVGATRHS--LRYLSTGSTSNFTKSLAYNFLASILGWPFV 187

Query: 219 VIWLYVGMLELFLTPNKVKFIILEV--IPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFN 276
           +I      L        +  I        I SL      + D + YG    V  N L +N
Sbjct: 188 LILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAPVSWNILFYN 247

Query: 277 FL----SSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWVLAIY 332
            +     SG + +G  PW++Y     L         +I GI   +   L A +   +A++
Sbjct: 248 VINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHLRLWPLWASLFTWIAVF 307

Query: 333 SILGHKEFRFVLPVLPIALIFSGYAF 358
           +   HKE RF+ P+  +  + +  AF
Sbjct: 308 TQQPHKEERFLYPIYGLITLSASIAF 333
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
          Length = 570

 Score =  259 bits (656), Expect = 1e-67
 Identities = 88/439 (20%), Positives = 144/439 (32%), Gaps = 41/439 (9%)

Query: 4   RKRKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLFC----LAFRVVNALLIQTY 59
           R+R+    D    +   S +  D+P    G       +  F     L +    +      
Sbjct: 7   RQRRPLISDSSSSSSTKSYSKTDKPGRSNGGDAEDGGLRWFLPFIALCYLRYMSATSNII 66

Query: 60  FNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIM 117
            + DE +   E  H  ++  G+ TWE+     +RSYL+ +      +       D    +
Sbjct: 67  HDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFHELAGRPASWWFGDDKVRV 126

Query: 118 IKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETV 177
             A RL   + SA+ D  L       YG  +AT+++         FF       +     
Sbjct: 127 FYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLTSGCFFASTSFLPSSFSM- 185

Query: 178 LTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI---RPTSAVIWLYVGMLELFLTPN 234
                          S    +  K+ + +A     +    P S + +L V +  L +   
Sbjct: 186 ----------YAISLSSGLLLFEKYAMAVAVSVVGVILGWPFSILAFLPVVIYSL-VKRF 234

Query: 235 KVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSG-GDYYGTHPWHWY 293
           K  FI   V  I  L  G + L+D   Y  W    LN L +N L  G    YGT    +Y
Sbjct: 235 KQAFIAGAVTTIFLL--GVSLLVDYYYYKRWTSSVLNLLIYNVLGGGESHLYGTEGALFY 292

Query: 294 F--------TQGFLVMLFTFTPFSIAGIIKSKNQ-KLSALILWVLAIYSILGHKEFRFVL 344
                        L MLF      I           +S + +W LA  S+  HKE RF+ 
Sbjct: 293 IRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIW-LAFMSLQPHKEERFLY 351

Query: 345 PVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPM 404
           P+ P+  + +  A  +          S  +   V    + +    + L      + +   
Sbjct: 352 PIYPLICVSAS-AVIENIPELFREKYSSRESLLVTITKYMR---PVILGCILCASHSRTF 407

Query: 405 ALYMSLFHQRGTEDAMNYL 423
           AL           +    L
Sbjct: 408 ALINGY---SAPLEVYKLL 423
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
 sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
 pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
 emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
           (Swiss Prot accession number P38376)~cDNA EST yk549e12.3
           comes from this gene~cDNA EST yk618d6.3 comes from this
           gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
           yk618d6.5 comes from>
          Length = 653

 Score =  251 bits (636), Expect = 2e-65
 Identities = 85/360 (23%), Positives = 134/360 (36%), Gaps = 49/360 (13%)

Query: 19  GASVNVGDEPDSFGGRIGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFG 78
            A+    D P SFG        +F   L+ R+  A+      + DE +   E  H  ++G
Sbjct: 41  KANNPDNDWPFSFGS-------VFKMLLSIRISGAIW-GIINDCDEVYNYWEPLHLFLYG 92

Query: 79  YGYMTWEWK--RGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYL 136
            G+ TWE+     IRSY +  L      L      DT  ++    RL   +F  +G+ Y 
Sbjct: 93  EGFQTWEYSPVYAIRSYFYIYLHYIPASLFANLFGDTKIVVFTLIRLTIGLFCLLGEYYA 152

Query: 137 YKLSDALYGGNVATWSLFCQMANWFIFFCLNR--TFSNCLETVLTIMGLYYWPCIRDSSI 194
           +             + +   + +  +F         S C+     I+G Y          
Sbjct: 153 FDAICKKINIATGRFFILFSIFSSGMFLASTAFVPSSFCMAITFYILGAY---------- 202

Query: 195 DYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGF 253
               N   G+   A +  +  P SAV+ L +    L L   +++FI+   + IG  + G 
Sbjct: 203 -LNENWTAGIFCVAFSTMVGWPFSAVLGLPIVADMLLLKGLRIRFILT-SLVIGLCIGGV 260

Query: 254 TCLLDRLMYGSWVIVPLNFLKFNFLSS-GGDYYGTHPWHWYFTQGF-------LVMLFTF 305
             + D   +G  V+ PLN   +N +S  G   YG  P  +Y    F           F F
Sbjct: 261 QVITDSHYFGKTVLAPLNIFLYNVVSGPGPSLYGEEPLSFYIKNLFNNWNIVIFAAPFGF 320

Query: 306 TPFSIAGIIKSK---------NQKLSALILW------VLAIYSILGHKEFRFVLPVLPIA 350
            P S+A   K            Q+ + +IL        L I+    HKE RF+ P+ P  
Sbjct: 321 -PLSLAYFTKVWMSQDRNVALYQRFAPIILLAVTTAAWLLIFGSQAHKEERFLFPIYPFI 379
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
          Length = 483

 Score =  249 bits (631), Expect = 9e-65
 Identities = 78/393 (19%), Positives = 136/393 (33%), Gaps = 43/393 (10%)

Query: 40  RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGY------------GYMTWEWK 87
              L  L       L+I  Y   +E +  L+  H  ++              G +     
Sbjct: 12  WPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHHEFPGVVP---- 66

Query: 88  RGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDAL 143
              R++L P++ A     +  +L +  +   Y      R +  +    G   L K     
Sbjct: 67  ---RTFLGPLVIAAFSSPVVYVLSLLEVSKFYS-QLIVRGVLGLGVISGLWTLQKEVRQQ 122

Query: 144 YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWG 203
           +G  VA    +     + + F   RT  N L   + +  L  W           + R+W 
Sbjct: 123 FGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAW-----------LQRRWA 171

Query: 204 LVI---AALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRL 260
           L +   A +    R   A++     +L L+     V  ++   IP G L LG T  +D  
Sbjct: 172 LFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSY 231

Query: 261 MYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK 320
            +   V      L +N + +    +GT P  WYF       L     F   G +  +   
Sbjct: 232 FWRYLVWPEGVVLGYNTVLNKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYA 291

Query: 321 LSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPR 380
           L+   L  +A+YS+L HKE RF++   P+  I +      +        S   K + +  
Sbjct: 292 LALPSLGFVALYSLLPHKELRFIIYTFPVLNIMAARGCTYILNK----KSWPYKVRAMLV 347

Query: 381 QNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
             H   +     +  ++   N P  + M   H+
Sbjct: 348 TGHILVNVAYTATSLYVSHFNYPGGVAMQQLHE 380
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
 gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
 emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
 gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
          Length = 488

 Score =  247 bits (627), Expect = 2e-64
 Identities = 73/354 (20%), Positives = 126/354 (34%), Gaps = 25/354 (7%)

Query: 65  HWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKA 120
           HWQ LE      F  G +        R++L P++ A        +L +  +   Y     
Sbjct: 48  HWQDLEQYDHLEFP-GVVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFYS-QLI 98

Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
            R +  +    G   L K     +G  VAT   +     + + F   RT  N L   + +
Sbjct: 99  VRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMFYCTRTLPNVLALPVVL 158

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFI 239
           + L  W                 + ++A A  + R    +    + +L L      V   
Sbjct: 159 LALAAW---------LRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRA 209

Query: 240 ILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL 299
           +   +P G L LG T  +D   +          L +N + +    +GT P  WYF     
Sbjct: 210 LRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALP 269

Query: 300 VMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFA 359
             L     F   G++  +    + L L  +A+YS+L HKE RF++   P+  I +    +
Sbjct: 270 RGLGCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCS 329

Query: 360 QMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
            +  +     S + K   +    H   +     +  ++   N P  + M   HQ
Sbjct: 330 YLLNNYK--KSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQ 381
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
           mannosyltransferase [Homo sapiens]
          Length = 488

 Score =  247 bits (626), Expect = 4e-64
 Identities = 72/354 (20%), Positives = 125/354 (34%), Gaps = 25/354 (7%)

Query: 65  HWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKA 120
           HWQ LE      F  G +        R++L P++ A        +L +  +   Y     
Sbjct: 48  HWQDLEQYDHLEFP-GVVP-------RTFLGPVVIAVFSSPAVYVLSLLEMSKFYS-QLI 98

Query: 121 PRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTI 180
            R +  +    G   L K     +G  VAT   +     + +     RT  N L   + +
Sbjct: 99  VRGVLGLGVIFGLWTLQKEVRRHFGAMVATMFCWVTAMQFHLMVYCTRTLPNVLALPVVL 158

Query: 181 MGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFI 239
           + L  W                 + ++A A  + R    +    + +L L      V   
Sbjct: 159 LALAAW---------LRHEWARFIWLSAFAIIVFRVELCLFLGLLLLLALGNRKVSVVRA 209

Query: 240 ILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL 299
           +   +P G L LG T  +D   +          L +N + +    +GT P  WYF     
Sbjct: 210 LRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVLNKSSNWGTSPLLWYFYSALP 269

Query: 300 VMLFTFTPFSIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFA 359
             L     F   G++  +    + L L  +A+YS+L HKE RF++   P+  I +    +
Sbjct: 270 RGLGCSLLFIPLGLVDRRTHAPTVLALGFMALYSLLPHKELRFIIYAFPMLNITAARGCS 329

Query: 360 QMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
            +  +     S + K   +    H   +     +  ++   N P  + M   HQ
Sbjct: 330 YLLNNYK--KSWLYKAGSLLVIGHLVVNAAYSATALYVSHFNYPGGVAMQRLHQ 381
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
           most likely an alpha 1,2 mannosyltransferase utilized
           for addition of the fourth, side-branching mannose onto
           the GPI core structure.; Smp3p [Saccharomyces
           cerevisiae]
 sp|Q04174|SMP3_YEAST SMP3 PROTEIN
 pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
 gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
 emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
          Length = 516

 Score =  239 bits (606), Expect = 7e-62
 Identities = 79/395 (20%), Positives = 146/395 (36%), Gaps = 42/395 (10%)

Query: 39  RRIFLFCLAFRVVNALLIQ-TYFNPDEHWQSLEVAHRTIFG-YGYMTWEW--KRGIRSYL 94
           R  +   L + +   L +  +Y +PDEH+Q +E+         G + WE+  K   RSY 
Sbjct: 3   RYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYG 62

Query: 95  HPMLFAFLYKLLQVTG---LDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW 151
             +L       +  +     D P +++ + RL   +   +   +L           V   
Sbjct: 63  PLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFM 122

Query: 152 SLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYW-PCIRDSSIDYPVNRKWGLVIAALA 210
                + ++  +     TFSN +ET+  I  L      + + +I     +   ++    +
Sbjct: 123 QKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFS 182

Query: 211 CAIR---PTSAVIWLY-VGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMY---G 263
             +       A I+L  + +   F   +   F +L +    S       L+D  +Y    
Sbjct: 183 FGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLL--SFSFSSCLFVLIDTNIYNNGK 240

Query: 264 SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSA 323
            +VI PLN LK+N        +G HP + +       ++      +I    K       A
Sbjct: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIFSGYKLDKLSTYA 300

Query: 324 LILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNH 383
           +I  +L + S   H+E RF++P++P+ +           ++ +  SS++  KK       
Sbjct: 301 IISGLLFL-SFFQHQELRFLVPLVPLLVTN---------LNWTPLSSTLVNKKIFKGTW- 349

Query: 384 TKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
                         L  NI MA  M + HQ G   
Sbjct: 350 --------------LLFNIIMAFIMGISHQAGIIQ 370
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
          Length = 516

 Score =  237 bits (599), Expect = 5e-61
 Identities = 80/395 (20%), Positives = 145/395 (36%), Gaps = 42/395 (10%)

Query: 39  RRIFLFCLAFRVVNALLIQ-TYFNPDEHWQSLEVAHRTIFG-YGYMTWEW--KRGIRSYL 94
           R  +   L + +   L +  +Y +PDEH+Q +E+         G + WE+  K   RSY 
Sbjct: 3   RYQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYG 62

Query: 95  HPMLFAFLYKLLQVTG---LDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW 151
             +L       +  +     D P +++ + RL   +   +   +L           V   
Sbjct: 63  PLLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFI 122

Query: 152 SLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYW-PCIRDSSIDYPVNRKWGLVIAALA 210
                + ++  +     TFSN +ET+  I  L      +   +I     +   ++    +
Sbjct: 123 KKSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNGKNIQRRNFKNSVILGLIFS 182

Query: 211 CAIR---PTSAVIWLY-VGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMY---G 263
             +       A I+L  + +   F   +   F +L +    S       L+D  +Y    
Sbjct: 183 FGVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLL--SFSFSSCLFVLIDTNIYNNGK 240

Query: 264 SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSA 323
            +VI PLN LK+N        +G HP + +       +L      +I    K       A
Sbjct: 241 GFVITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQILGPVLLLAIFSGYKLDKLSTYA 300

Query: 324 LILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNH 383
           +I  +L + S   H+E RF++P++P+ +           ++ +  SS++  KK       
Sbjct: 301 IISGLLFL-SFFQHQELRFLVPLVPLLVTN---------LNWTPLSSTLVNKKIFKGTW- 349

Query: 384 TKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTED 418
                         L  NI MA  M + HQ G   
Sbjct: 350 --------------LLFNIIMAFIMGISHQAGIIQ 370
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
           - fission yeast (Schizosaccharomyces pombe)
 emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
           [Schizosaccharomyces pombe]
          Length = 577

 Score =  232 bits (587), Expect = 1e-59
 Identities = 102/519 (19%), Positives = 177/519 (33%), Gaps = 52/519 (10%)

Query: 37  SPRRIFLF-CLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWK--RGIRSY 93
           S   ++ F  LA   + +   +   + DE +   E  H  ++GYG  TWE+     IRS+
Sbjct: 11  SVSFVWTFSILAVLRLTSASFRVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPEYAIRSW 70

Query: 94  LHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSL 153
            +  L A    L +  GL   + +    R + + FSA  +  L       +   VA    
Sbjct: 71  FYIALHAVPGFLARGLGLSRLH-VFYFIRGVLACFSAFCETNLILAVARNFNRAVALHLT 129

Query: 154 FCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAI 213
                N  ++        +     +  + L      + S        K    I   A   
Sbjct: 130 SVLFVNSGMWSASTSFLPSSFAMNMVTLALSA----QLSPPSTKRTVKVVSFITIGAVIG 185

Query: 214 RPTSAVIWLYVGMLELF-LTPNKVKFIILEV--IPIGSLVLGFTCLLDRLMYGSWVIVPL 270
            P SA + +   +LEL  L              I +  L+ G    +D L Y     V  
Sbjct: 186 WPFSAALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQFVAW 245

Query: 271 NFLKFNFLSS---GGDYYGTHPWHWYFTQ---------------GFLVMLFTFTPFSIAG 312
           N +K+N L+    G D YGT PW +YF                 G LV+L  FT +    
Sbjct: 246 NIVKYNVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLVLLAAFTNWINLD 305

Query: 313 IIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSV 372
                +  +S   +W L I+ I  HKE RF+ P+ P+  + +            S    +
Sbjct: 306 SFLDLSSVISPFYIW-LFIFIIQPHKEERFMYPIYPVLCLAAAIGLD------MSLKLMI 358

Query: 373 TKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGRV 432
                +     +K+  +  +   + +   + +A  +++ +          +S       V
Sbjct: 359 QILSSINETVRSKFPVRFVVLCVYAIIGCLSIARILAIQNYNAPMIIYPAISFLETDNNV 418

Query: 433 KSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGELDESD-----QFLVNPLGFASEL 487
            + +    C    +Y       P  F     S  K    E D     +F+ +   + +  
Sbjct: 419 TTNV----CVGKEWYRY-----PSTFFLPDNSRLKFVKSEFDGILPGEFVESNSTWWNRE 469

Query: 488 ARNWSEPPSHIVLFASEETKLRDFMIQHSFKEVRRFFHA 526
              + + P H+  F +EE      +    F     F H+
Sbjct: 470 G--YYQIPEHMNEFNNEEPTRYTSLESCDFLIDLEFDHS 506
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
 pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
          Length = 533

 Score =  226 bits (573), Expect = 6e-58
 Identities = 85/408 (20%), Positives = 156/408 (37%), Gaps = 66/408 (16%)

Query: 41  IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGY-MTWEW--KRGIRSYLHP- 96
           I+ F L  R   +    +Y +PDEH QS ++    +FG+   + WE+  K+ IRS +   
Sbjct: 10  IYTFLLILRFWFSQ-GSSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSVVPLN 68

Query: 97  --MLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLF 154
             +L  FL          +PY ++   RL   + S + DL ++ +         A WS  
Sbjct: 69  VMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLIDLSIWNIVPL-----NARWSAL 123

Query: 155 CQMANWFIF-FCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIA------ 207
              ++ F+       TF+N +ET+   + + +   +    ++  ++  +  ++A      
Sbjct: 124 LLYSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIVSVLG 183

Query: 208 ------ALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLL-DRL 260
                  LA  I P    I+  V   +  +   K  F+ L +    S      C+L D  
Sbjct: 184 FFTRITFLAFVIAP---YIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDYK 240

Query: 261 MYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQK 320
            YG +VI   N LK+N        +G H    +F     ++           + K  + +
Sbjct: 241 FYGVFVITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGPLI-----FVPKLWDVR 295

Query: 321 LSALILWVL--AIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQV 378
             A  LW+L   I S+  H+E RF+LP   I ++ SG       +               
Sbjct: 296 KPATWLWLLPVFILSLFPHQEPRFLLPAASIFIVNSGCLVRSYWIK-------------- 341

Query: 379 PRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDE 426
                          ++ + A  + +A++  + HQ G   A+  + + 
Sbjct: 342 --------------FLFVMYA--VVLAVFFGIMHQNGVIPAVLEVKNI 373
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
 gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
          Length = 492

 Score =  216 bits (546), Expect = 8e-55
 Identities = 50/289 (17%), Positives = 108/289 (37%), Gaps = 19/289 (6%)

Query: 91  RSYLHPMLFAFLYKLLQVTGLDTPYIM-----IKAPRLMQSIFSAIGDLYLYKLSDALYG 145
           R+++ P+  A L   +        + +     +   R    + +A+  LY  +  +  +G
Sbjct: 58  RTFIGPISLAILSSPMSFIFR--FWAIPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFG 115

Query: 146 GNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLV 205
              A +        +   F ++R   N    +L ++        R     Y    ++   
Sbjct: 116 RETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVF-----ERLLEGRYESAVRYA-- 168

Query: 206 IAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEV---IPIGSLVLGFTCLLDRLMY 262
             A     R    +++  + +  +     KV      +   + I ++ L  +  +D   +
Sbjct: 169 -TASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFW 227

Query: 263 GSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL-VMLFTFTPFSIAGIIKSKNQKL 321
           G  +      + FN + +    YGT P+ WYF       +L T     +  ++  +  ++
Sbjct: 228 GRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQI 287

Query: 322 SALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSS 370
               +  + +YS L HKE RF++ VLPI  + +    A+M ++   S  
Sbjct: 288 VLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFF 336
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
          Length = 278

 Score =  215 bits (544), Expect = 1e-54
 Identities = 67/283 (23%), Positives = 122/283 (42%), Gaps = 60/283 (21%)

Query: 298 FLVMLFTFTPFSIAGIIKSKNQK------------LSALILWVLAIYSILGHKEFRFVLP 345
             ++L    P    G+    +++            +   IL  L +YS L HKEFRF+ P
Sbjct: 2   LPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIFP 61

Query: 346 VLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMA 405
           + P+ ++ S +   +++                  +++ K    L+  ++ +   ++ +A
Sbjct: 62  LQPLFILISSFGLLRLD------------------RDYWKRLSGLKSLLWLVPFVSVFIA 103

Query: 406 LYMSLFHQRGTEDAMNYLSDEAYKGRVKSILFLMPCHSTPYYSTLH-----------RNI 454
           L +  FH+ G+ + M +L +E     + S+ F+MPCHSTP  S LH            N 
Sbjct: 104 LLLDTFHESGSIEVMKFLHEEP---EIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCNP 160

Query: 455 PMQFLDCTPSAEKG--ELDESDQFLVN---------PLGFASEL---ARNWS-EPPSHIV 499
           P+  L    +  K    +DESD    +         P  F  +L    + +S E P+++V
Sbjct: 161 PLHLLGDPEAYSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLV 220

Query: 500 LFASEETK-LRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVVVY 541
           +F   E   L+DF+   S+ E  RFF++    D      +++Y
Sbjct: 221 VFEHMENAFLKDFLKDSSYIEYNRFFNSLAHWDSRRSGDIIIY 263
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
          Length = 369

 Score =  210 bits (530), Expect = 7e-53
 Identities = 50/289 (17%), Positives = 108/289 (37%), Gaps = 19/289 (6%)

Query: 91  RSYLHPMLFAFLYKLLQVTGLDTPYIM-----IKAPRLMQSIFSAIGDLYLYKLSDALYG 145
           R+++ P+  A L   +        + +     +   R    + +A+  LY  +  +  +G
Sbjct: 16  RTFIGPISLAILSSPMSFIFR--FWAIPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFG 73

Query: 146 GNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLV 205
              A +        +   F ++R   N    +L ++        R     Y    ++   
Sbjct: 74  RETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMIVF-----ERLLEGRYESAVRYA-- 126

Query: 206 IAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEV---IPIGSLVLGFTCLLDRLMY 262
             A     R    +++  + +  +     KV      +   + I ++ L  +  +D   +
Sbjct: 127 -TASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFW 185

Query: 263 GSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFL-VMLFTFTPFSIAGIIKSKNQKL 321
           G  +      + FN + +    YGT P+ WYF       +L T     +  ++  +  ++
Sbjct: 186 GRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRLPQI 245

Query: 322 SALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSS 370
               +  + +YS L HKE RF++ VLPI  + +    A+M ++   S  
Sbjct: 246 VLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFF 294
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
 dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
          Length = 579

 Score =  209 bits (529), Expect = 7e-53
 Identities = 91/394 (23%), Positives = 138/394 (34%), Gaps = 74/394 (18%)

Query: 16  GADGASVNVGDEPDSFGGRIG-------SPRRIFLFCLAFRVVNALLIQT-YFNPDEHWQ 67
           G+  ASV  G      G           + R ++      RV+  LL QT Y +PDE +Q
Sbjct: 5   GSSVASVAAGTSFQVLGPVCWQQLDLKMAVRVLWGGLSLLRVLWCLLPQTGYVHPDEFFQ 64

Query: 68  SLEVAHRTIFG-YGYMTWEW--KRGIRSYLHPMLF-AFLYKLLQVT-------GLDTPYI 116
           S EV    I G      WE+      RS L P+L     + LL++        GL + Y 
Sbjct: 65  SPEVMAEDILGVQAARPWEFYPSSSCRSVLFPLLISGSTFWLLRLWEELGPWPGLVSGYA 124

Query: 117 MIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMA-NWFIFFCLNRTFSNCLE 175
           ++  PRL+ +  S   D  +Y L+  +       W+    ++ ++       RTFSN +E
Sbjct: 125 LLVGPRLLLTALSFALDGAVYHLAPPMGAD---RWNALALLSGSYVTLVFYTRTFSNTIE 181

Query: 176 TVLTIMGLYY------WPCIRDSSIDYPVNRKWGLV----------IAALACAIRPTSAV 219
            +L    L        W   R      P  R W L              LA A+ P    
Sbjct: 182 GLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWLLGGIVAAGFFNRPTFLAFAVVP--LY 239

Query: 220 IWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMY------GSWVIVPLNFL 273
           +W   G     L     +   L ++P  +L        D   +       + V+ P+NFL
Sbjct: 240 LWGTRGATNPGLKSLTRE--ALVLLPGATLTAAVFVATDSWYFSSPATSRNLVLTPVNFL 297

Query: 274 KFNFLSSGGDYYGTHPWHWYF-TQGFL------------------VMLFTFTPFSIAGII 314
            +N        +GTH    +    GFL                  V L       +   +
Sbjct: 298 HYNLNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQQLQVGLQASAQMGLLRAL 357

Query: 315 KSKNQ------KLSALILWVLAIYSILGHKEFRF 342
            +++        L  L    LA+ S   H+E RF
Sbjct: 358 GARSLLSSPRSYLLLLYFMPLALLSAFSHQEARF 391
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
           architecture [Schizosaccharomyces pombe]
          Length = 547

 Score =  202 bits (511), Expect = 1e-50
 Identities = 57/355 (16%), Positives = 121/355 (34%), Gaps = 34/355 (9%)

Query: 66  WQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQ 125
           W   +V     F             RS++  +  A L  +            + A R   
Sbjct: 49  WDLSKVYDHLEFPGAVK--------RSFIPSLFIAVLSYIPSWFVNP-----LLAARWTI 95

Query: 126 SIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYY 185
              S      +       +G       +    A + + + ++R  SN    + T      
Sbjct: 96  GYLSWESMNSVSCSISKRFGTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIAT------ 149

Query: 186 WPCIRDSSIDYPVNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILEVI 244
                  S+    N    + I   A AI R   A++ + + +  L      +  ++L  I
Sbjct: 150 ---NHSLSLLLKNNYYGSISILVFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGI 206

Query: 245 PIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFT 304
                 +G + L+D   +G+W    L    FN +      +GT P+++YF    + + + 
Sbjct: 207 SSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGKSSDWGTSPFYYYF----VRLPWL 262

Query: 305 FTPFSIAGIIKSKNQKLSA------LILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
           F   +    +      +        + L+ + +YS LGHKE+RF++  +P     S    
Sbjct: 263 FLNPTTLLFLLISFVYIKPARLLIYVPLFFIFVYSFLGHKEWRFIIYSIPWFNAASAIG- 321

Query: 359 AQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQ 413
           A +  + S     + +  ++   +   +       + ++     P  L ++  ++
Sbjct: 322 ASLCFNASKFGKKIFEILRLMFFSGIIFGFIGSSFLLYVFQYAYPGGLALTRLYE 376
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
           chromosome I precursor [Leishmania major]
          Length = 822

 Score =  168 bits (422), Expect = 3e-40
 Identities = 49/319 (15%), Positives = 97/319 (30%), Gaps = 65/319 (20%)

Query: 44  FCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEW--KRGIRSYLHPMLFAF 101
             L+     A       + DE +  +E  H  ++G G  TWE   +  +RS+L   + A+
Sbjct: 16  LLLSLTHYFASSFLPISDCDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSWLFLWIHAW 75

Query: 102 LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWF 161
              L++     +   +    R++    +A+ +L+          G  A  +L   +AN+ 
Sbjct: 76  PVVLIRGAASLSSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLLANYP 135

Query: 162 IFFCLNRTFSNCLETVLTIMGLYYW----PCIRDSSI----------------------- 194
           I              +   + L  W         S++                       
Sbjct: 136 IQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALLSRVGDRPTQNTMPAAAAGTAQL 195

Query: 195 -----DYPVNR------------------KWGLVIAALACAI------RPTSAVIWLYVG 225
                  P +                    W +  AAL  ++       P +A+I   VG
Sbjct: 196 SMMVPPSPSSAPTLHSSSASPPSAPPRHLCWFIG-AALCFSVLAVVTGWPFAALISALVG 254

Query: 226 MLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSS---GG 282
           +  L   P +    +   +    +      + D   Y  W +   N + +N       G 
Sbjct: 255 LDLLLRFPVR---TLACTLGSLLVACAAVFVADVRYYCRWTLSSWNVVMYNGFGGSGRGP 311

Query: 283 DYYGTHPWHWYFTQGFLVM 301
           + +G  P  +++    L  
Sbjct: 312 ELFGVEPIFFFWKNLMLNF 330
 Score =  115 bits (286), Expect = 3e-24
 Identities = 27/155 (17%), Positives = 55/155 (35%), Gaps = 2/155 (1%)

Query: 44  FCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEW--KRGIRSYLHPMLFAF 101
             L+     A       + DE +  +E  H  ++G G  TWE   +  +RS+L   + A+
Sbjct: 16  LLLSLTHYFASSFLPISDCDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSWLFLWIHAW 75

Query: 102 LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWF 161
              L++     +   +    R++    +A+ +L+          G  A  +L   +AN+ 
Sbjct: 76  PVVLIRGAASLSSVRVYFYLRMLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLLANYP 135

Query: 162 IFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDY 196
           I              +   + L  W   +  +   
Sbjct: 136 IQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSS 170
 Score = 40.0 bits (93), Expect = 0.11
 Identities = 12/38 (31%), Positives = 17/38 (44%), Gaps = 1/38 (2%)

Query: 321 LSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAF 358
           +    +W L   SI  HKE RF+ P  P  L+ +    
Sbjct: 439 IMPFFVWFLFWMSI-AHKEERFMSPAYPFMLLAATRTL 475
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
          Length = 198

 Score =  167 bits (420), Expect = 4e-40
 Identities = 46/173 (26%), Positives = 75/173 (42%), Gaps = 16/173 (9%)

Query: 6   RKNAGGDGDGGADGASVNVGDEPDSFGGRIGSPRRIFLF-CLAFRVVNALLIQTYFNPDE 64
           R+  G    GGA+  +   G++     G++ +P     F CL    + A L+    + DE
Sbjct: 28  RELLGSREAGGAEHRTELSGNK----AGQVWAPEGSTAFKCLLSARLCAALLSNISDCDE 83

Query: 65  HWQSLEVAHRTIFGYGYMTWEWK--RGIRSY----LHPMLFAFLYKLLQVTGLDTPYIMI 118
            +   E  H  I+G G+ TWE+     IRSY    LH    AF  ++LQ   +   Y + 
Sbjct: 84  TFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFL- 142

Query: 119 KAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANWFIFFCLNRTFS 171
              R + +  S I +LY YK     +G +V+   L   + +    FC +  + 
Sbjct: 143 ---RCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLSTG-MFCSSSVYP 191
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
 sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
 pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
          Length = 551

 Score =  161 bits (406), Expect = 2e-38
 Identities = 56/335 (16%), Positives = 117/335 (34%), Gaps = 63/335 (18%)

Query: 68  SLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFAFLYKL------LQVTGLDTPYIMIKAP 121
            +       F  G +        R+++  ++ A L +       L  T   T   +    
Sbjct: 45  DISQYDHLKFP-GVVP-------RTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVV 96

Query: 122 RLMQSIFSAIGDLYLYKLSDALYGGNV------------------ATWSLFCQMANWFIF 163
           R +  + + +  +YL      ++                       TW L   + ++ + 
Sbjct: 97  RGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLM 156

Query: 164 FCLNRTFSN-CLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLV----IAALACAIRPTSA 218
           F   RT  N  +   LT + L  W  +   +    ++    +V    ++AL+  I   S 
Sbjct: 157 FYSTRTLPNFVMTLPLTNVAL-GWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFS- 214

Query: 219 VIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGF----TCLLDRLMYGSWVIVPLNFLK 274
           VI+  + + +               I  G   LG     +  +D   +  W +  ++   
Sbjct: 215 VIFKKISLFD--------------AIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFL 260

Query: 275 FNFLSSGGDYYGTHPWHWYFTQGFLVMLF-----TFTPFSIAGIIKSKNQKLSALILWVL 329
           FN ++     +G  P   YFT  +L M+F         +    +  +K + +S   L+ +
Sbjct: 261 FNVVAGYASKWGVEPVTAYFTH-YLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHI 319

Query: 330 AIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVS 364
            + S   HKE+RF++  +P  ++      A +  +
Sbjct: 320 IVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLWEN 354
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
          Length = 830

 Score =  138 bits (345), Expect = 3e-31
 Identities = 51/279 (18%), Positives = 89/279 (31%), Gaps = 60/279 (21%)

Query: 198 VNRKWGLVIAALACAI-RPTSAVIWLYVGMLELFLT-----------PNKVKFIILEVIP 245
           +     +    +A    RPT  +    +    L                ++    L  +P
Sbjct: 222 LQHLMAMSTICVAGVFNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALP 281

Query: 246 IGSLVLGFTCLLDRLMYGS---------------WVIVPLNFLKFNFLSSGGDYYGTHPW 290
              L        D L Y                 +V  P NF+K N  S+    +G HP 
Sbjct: 282 ALVLF----IFCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPC 337

Query: 291 HWY--------FTQGFLVMLFTFTPFSI------AGIIKSKNQKLSAL---ILWVLAIYS 333
           + +        F    L  L  F    +        ++      +S +   I   L   S
Sbjct: 338 YVHLMVNMPMLFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLS 397

Query: 334 ILGHKEFRFVLPV-LPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRL 392
           ++ H+E RF+LPV  P+ L+ +        ++G S+     K   + R  + K       
Sbjct: 398 LINHQEPRFLLPVTFPLILLHAPK-----LITGFSAKYPFQKDHPLLRLFYDKLLSSKAS 452

Query: 393 SVYFL---LATNIPMALYMSLFHQRGTEDAMNYLSDEAY 428
             Y L     +N+ + L+    HQ G        +D ++
Sbjct: 453 GPYLLKIWYVSNVALTLFFGFIHQAG---VYPLAADISH 488
 Score = 56.0 bits (134), Expect = 2e-06
 Identities = 41/156 (26%), Positives = 61/156 (38%), Gaps = 18/156 (11%)

Query: 44  FCL-AFRVVNALLIQT-YFNPDEHWQSLEVAHRTIFGYGY-MTWEWKRGIRSYLHPMLFA 100
           FC  A R++   + Q  Y +PDE +QS+EV     F   +  TWE+   +      + FA
Sbjct: 21  FCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIVLPFA 80

Query: 101 FLYKLLQV-------------TGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGN 147
            L                     L   Y  +  PRL+ ++ S   D  L++    LYG  
Sbjct: 81  LLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFR-ICRLYGLR 139

Query: 148 VATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGL 183
                L    ++W +     RTFSN LE  +    L
Sbjct: 140 FE-IRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLL 174
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
          Length = 197

 Score =  135 bits (338), Expect = 2e-30
 Identities = 41/210 (19%), Positives = 82/210 (38%), Gaps = 20/210 (9%)

Query: 145 GGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGL 204
           G       +    A + + + ++R  SN    + T             S+    N    +
Sbjct: 1   GTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIAT---------NHSLSLLLKNNYYGSI 51

Query: 205 VIAALACAI-RPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYG 263
            I   A AI R   A++ + + +  L      +  ++L  I      +G + L+D   +G
Sbjct: 52  SILVFAAAIVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWG 111

Query: 264 SWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSA 323
           +W    L    FN +      +GT P+++YF    + + + F   +    +      +  
Sbjct: 112 AWCWPELEAFLFNVVEGKSSDWGTSPFYYYF----VRLPWLFLNPTTLLFLLISFVYIKP 167

Query: 324 ------LILWVLAIYSILGHKEFRFVLPVL 347
                 + L+ + +YS LGHKE+RF++  +
Sbjct: 168 ARLLIYVPLFFIFVYSFLGHKEWRFIIYSI 197
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
          Length = 457

 Score =  121 bits (303), Expect = 3e-26
 Identities = 49/241 (20%), Positives = 76/241 (31%), Gaps = 52/241 (21%)

Query: 150 TWSLFCQMA-NWFIFFCLNRTFSNCLETVLTIMGLYY------WPCIRDSSIDYPVNRKW 202
            W+    ++ ++       RTFSN +E +L    L        W   R      P  R W
Sbjct: 33  RWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSW 92

Query: 203 GLV----------IAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLG 252
            L              LA A+ P    +W   G     L     +   L ++P  +L   
Sbjct: 93  LLGGIVAAGFFNRPTFLAFAVVP--LYLWGTRGATNPGLKSLTRE--ALVLLPGATLTAA 148

Query: 253 FTCLLDRLMY------GSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYF-TQGFL------ 299
                D   +       + V+ P+NFL +N        +GTH    +    GFL      
Sbjct: 149 VFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLH 208

Query: 300 ------------VMLFTFTPFSIAGIIKSKNQ------KLSALILWVLAIYSILGHKEFR 341
                       V L       +   + +++        L  L    LA+ S   H+E R
Sbjct: 209 AQALQAAWQRLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEAR 268

Query: 342 F 342
           F
Sbjct: 269 F 269
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
          Length = 283

 Score =  117 bits (291), Expect = 6e-25
 Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 29/144 (20%)

Query: 275 FNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWV----LA 330
           FN +  G   +G HPW+WY   G   +L       I G++     + S L  +     + 
Sbjct: 131 FNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYII 190

Query: 331 IYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKL 390
           ++S+L HKE RF+LP++P+  I++G AF                      QN  KW    
Sbjct: 191 VHSLLPHKEQRFLLPIIPLLCIYAGGAF----------------------QNLKKWRG-- 226

Query: 391 RLSVYFLLATNIPMALYMSLFHQR 414
             ++  ++A NI +AL+ S +HQ+
Sbjct: 227 -SAMAVMIAINIGIALFTSRYHQK 249
 Score = 88.7 bits (218), Expect = 2e-16
 Identities = 27/68 (39%), Positives = 45/68 (65%)

Query: 34  RIGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSY 93
           R+ +  R+    + FR ++  L+ ++F PDE +QS EVAH  ++G G+++WEW+  +RS+
Sbjct: 64  RMRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSF 123

Query: 94  LHPMLFAF 101
            HP L AF
Sbjct: 124 FHPALIAF 131
>gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protein MGC3136 [Mus musculus]
          Length = 385

 Score =  115 bits (288), Expect = 1e-24
 Identities = 44/232 (18%), Positives = 77/232 (32%), Gaps = 39/232 (16%)

Query: 40  RIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGY------------GYMTWEWK 87
              L  L       L+I  Y   +E +  L+  H  ++              G +     
Sbjct: 12  WPLLGLLVTVATIHLVICPYTKVEESFN-LQATHDLLYHQLDIDKYDHHEFPGVVP---- 66

Query: 88  RGIRSYLHPMLFAF----LYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDAL 143
              R++L P++ A     +  +L +  +   Y      R +  +    G   L K     
Sbjct: 67  ---RTFLGPLVIAAFSSPVVYVLSLLEVSKFYS-QLIVRGVLGLGVISGLWTLQKEVRQQ 122

Query: 144 YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWG 203
           +G  VA    +     + + F   RT  N L   + +  L  W           + R+W 
Sbjct: 123 FGATVAVMFCWISATQFHLMFYCTRTLPNVLALAVVLPALTAW-----------LQRRWA 171

Query: 204 LVI---AALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLG 252
           L +   A +    R   A++     +L L+     V  ++   IP G L LG
Sbjct: 172 LFVWLSAFVIIGFRAELAMLLGIALLLTLYQRRLTVARVLRHAIPAGLLCLG 223
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
 gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
           [Caenorhabditis elegans]
          Length = 232

 Score =  111 bits (277), Expect = 3e-23
 Identities = 41/144 (28%), Positives = 67/144 (46%), Gaps = 29/144 (20%)

Query: 275 FNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALILWV----LA 330
           FN +  G   +G HPW+WY   G   +L       I G++     + S L  +     + 
Sbjct: 67  FNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGPNIFRPSLLPFFATITYII 126

Query: 331 IYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKL 390
           ++S+L HKE RF+LP++P+  I++G AF                      QN  KW    
Sbjct: 127 VHSLLPHKEQRFLLPIIPLLCIYAGGAF----------------------QNLKKWRG-- 162

Query: 391 RLSVYFLLATNIPMALYMSLFHQR 414
             ++  ++A NI +AL+ S +HQ+
Sbjct: 163 -SAMAVMIAINIGIALFTSRYHQK 185
 Score = 84.0 bits (206), Expect = 5e-15
 Identities = 26/67 (38%), Positives = 44/67 (64%)

Query: 35  IGSPRRIFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYL 94
           + +  R+    + FR ++  L+ ++F PDE +QS EVAH  ++G G+++WEW+  +RS+ 
Sbjct: 1   MRTTLRLLAKLVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFF 60

Query: 95  HPMLFAF 101
           HP L AF
Sbjct: 61  HPALIAF 67
>ref|NP_276829.1| (NC_000916) unknown [Methanothermobacter thermautotrophicus]
 pir||G69096 hypothetical protein MTH1717 - Methanobacterium thermoautotrophicum
           (strain Delta H)
 gb|AAB86189.1| (AE000928) unknown [Methanothermobacter thermautotrophicus]
          Length = 557

 Score = 43.5 bits (102), Expect = 0.009
 Identities = 48/341 (14%), Positives = 104/341 (30%), Gaps = 47/341 (13%)

Query: 89  GIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNV 148
           G+++Y +P LF  +   L +           +P L  +       L +YK++   +    
Sbjct: 67  GLKAYAYPPLFHVMGYGLYLLFRSELVFFFISPLLGTATV-----LVIYKVARETFEREE 121

Query: 149 ATWSLFCQMANWFIFFCLNRTF-SNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIA 207
                    +    F      F    +  +LT   LY       ++  YP   K+ L   
Sbjct: 122 VALLSAFLFSMVPSFVARTSVFIPESMGLLLTSGILYMLVKYLKTTPGYPDIDKFEL--K 179

Query: 208 ALACAIRPTSAVIWLYVGMLELFLTPNK-VKFIILEVIPIGSLVLGFTC----------- 255
           A +   R     I   + +  ++L  ++   F+++ ++ +    L  +            
Sbjct: 180 AFSNLFRGDLRYILGGLALFVIYLFTHRGWVFLLIALLLLAVTFLTPSFRKRPLEFGLIF 239

Query: 256 ------LLDRL-MYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPF 308
                 +++ +     +  VP+  L F             P      Q  L +       
Sbjct: 240 LLIGAGIIEFITFAARFQSVPVTILGF-------------PKWMGVLQLILGIYGASLLL 286

Query: 309 SIAGIIKSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSS 368
                I  +   + A    ++  YS      FR     +P++ +  GYAF++++     +
Sbjct: 287 RSKNPIH-RFLIIWATAFMIIGTYSF----RFRDPYAAIPLS-LMGGYAFSEVKGR-LYA 339

Query: 369 SSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMS 409
           S        + R         +   +  +         Y  
Sbjct: 340 SKRFKSYSIMKRDVKPFLRTGIFALLVLMPLAQGAAIAYTG 380
>ref|NP_440407.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
 pir||S75173 hypothetical protein sll1946 - Synechocystis sp. (strain PCC 6803)
 dbj|BAA17087.1| (D90903) ORF_ID:sll1946~unknown protein [Synechocystis sp. PCC
           6803]
          Length = 825

 Score = 40.0 bits (93), Expect = 0.11
 Identities = 51/359 (14%), Positives = 108/359 (29%), Gaps = 43/359 (11%)

Query: 44  FCLAFRVVNA-LLIQTYFNPDEHWQSLEVAHRTIFGYGYMT-----------WEWKRGIR 91
             LA   + +  L + +   D+   + + ++   +G  Y+            W     + 
Sbjct: 14  LLLAMVWLGSNGLDRLWLGMDQTVPAWDQSNHLSYGLEYLQALRSPEFLSGEWWRSFWML 73

Query: 92  SYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW 151
           S  +P L   +    Q  G     + + +      ++S I  L +Y L   L+   +  W
Sbjct: 74  SPKYPPLTYIVNAPFQGLGGPGSDLALLS----NWLWSGILILSVYGLGKKLFSREIGLW 129

Query: 152 SLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALAC 211
           ++   +    +         +      T++        +++         W +       
Sbjct: 130 AVAIMVLIPRLIHSRLIVLLDSPLLAFTLLSFTCLTYWKEAE-GRRSQWLWAIAAGVGLG 188

Query: 212 AIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLV-LGFTCLLDRLMYG-SWVIVP 269
               +   I  Y+    + L      +          LV L  +  L    Y  +W+ + 
Sbjct: 189 LGLLSKQSIIFYLFFPLVGLG-LWSIWTKQWQRLAQLLVGLLASIPLWYPWYRTNWIYLF 247

Query: 270 LNFLKFN----FLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSALI 325
                 N     L           W +Y+      + + +    + G+I S   +  A +
Sbjct: 248 STAQNSNAIPATLEGDPPVNTLAAWTYYWQDLPNALSWVWLIPPLVGVILSLLNRFPASL 307

Query: 326 -----------LWVLAIY--------SILGHKEFRFVLPVLPIALIFSGYAFAQMEVSG 365
                      L  L  Y        S + +K+ R++LP LPI  IF  +   +     
Sbjct: 308 QIPSWREAKPGLLWLGYYYGGTYLICSAIQNKDDRYILPYLPIVAIFLAFGLTRWCGRW 366
>ref|NP_485359.1| (NC_003272) unknown protein [Nostoc sp. PCC 7120]
 dbj|BAB73273.1| (AP003585) ORF_ID:all1316~unknown protein [Nostoc sp. PCC 7120]
          Length = 523

 Score = 40.0 bits (93), Expect = 0.12
 Identities = 39/242 (16%), Positives = 85/242 (35%), Gaps = 23/242 (9%)

Query: 93  YLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATW- 151
           Y+ P ++  L  L      +     +   R + ++ S I    +Y L   L+      + 
Sbjct: 96  YVFPPIYPVLTILWSYLFNNWFDNGLVIQRSLAALLSVIAIWAIYWLGLELFVSKTTAFV 155

Query: 152 -SLFCQMANWFIFFCL-NRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAAL 209
            ++   ++ + + +    R +S  + T +   G          ++       W +    L
Sbjct: 156 AAVIVAISPFHLQYAQIIRPYSILIATTVIACGCLL------KAMHLKNLWWWLIY--GL 207

Query: 210 ACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVP 269
           +  I   S +++ +V +              L+ +    LVLG + L     +  W+   
Sbjct: 208 SIVIGLYSNLLFAFVLVAHTVYVLINESLRNLKSLTAYFLVLGISTLA----FLPWLWAF 263

Query: 270 LN--FLKFNF--LSSGGDYYGT-HPWHWYFTQGFLVMLFTFTPFSIAGIIKSKNQKLSAL 324
           +N   LK++   +S     +G  + W       FL     + PF     +K+     + +
Sbjct: 264 INSSMLKYSVEQVSDKSSLFGLINAWLKGIQNLFLD---LYHPFFSPNFLKAAQWFFTPI 320

Query: 325 IL 326
           IL
Sbjct: 321 IL 322
CPU time:   160.58 user secs.	    3.00 sys. secs	  163.58 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.317    0.176    0.495 

Gapped
Lambda     K      H
   0.270   0.0617    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 379711996
Number of Sequences: 887402
Number of extensions: 20590159
Number of successful extensions: 90718
Number of sequences better than 10.0: 726
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 689
Number of HSP's that attempted gapping in prelim test: 89569
Number of HSP's gapped (non-prelim): 1373
length of query: 548
length of database: 277,845,442
effective HSP length: 52
effective length of query: 496
effective length of database: 231,700,538
effective search space: 114923466848
effective search space used: 114923466848
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 76 (33.6 bits)