Sequences with E-value BETTER than threshold (0.002)
gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melan... 658 0.0
ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class ... 512 e-144
gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, c... 507 e-142
ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class ... 503 e-141
ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycoli... 493 e-138
pir||T51430 dolichyl-phosphate-mannose--glycolipid alpha-mannosy... 469 e-131
dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltra... 395 e-109
pir||T41079 probable alpha 1,2 mannosyltransferase - fission yea... 376 e-103
ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl i... 320 6e-86
gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melano... 309 9e-83
emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus mus... 300 4e-80
gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipola... 286 6e-76
emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens] 285 9e-76
gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 ... 284 3e-75
gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens] 283 4e-75
ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; si... 283 8e-75
ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo ... 274 4e-72
emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-... 273 6e-72
ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans] ... 269 6e-71
dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Tryp... 261 3e-68
ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster] >... 259 7e-68
pir||T50116 probable mannosyltransferase involved in N-glycosyla... 251 2e-65
pir||T39659 cell wall biosynthesis protein N3265 homolog - fissi... 250 4e-65
pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans 247 3e-64
sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CH... 241 2e-62
emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae] 240 3e-62
ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl i... 238 2e-61
ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Sacch... 230 4e-59
ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [A... 228 3e-58
ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans] ... 225 1e-57
gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabi... 216 9e-55
emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae] 215 1e-54
ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose f... 214 4e-54
ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo... 210 4e-53
gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan ... 177 6e-43
ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo... 171 3e-41
pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans 149 2e-34
dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharom... 149 2e-34
gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protei... 147 4e-34
ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]... 142 2e-32
gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melano... 128 2e-28
dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicul... 102 2e-20
emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein... 84 8e-15
Alignments
>gb|AAF47795.1| (AE003479) CG12006 gene product [Drosophila melanogaster]
Length = 512
Score = 658 bits (1681), Expect = 0.0
Identities = 512/512 (100%), Positives = 512/512 (100%)
Query: 1 MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVY 60
MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVY
Sbjct: 1 MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVY 60
Query: 61 PLLIAGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLANTLEASLTT 120
PLLIAGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLANTLEASLTT
Sbjct: 61 PLLIAGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLANTLEASLTT 120
Query: 121 IALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIG 180
IALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIG
Sbjct: 121 IALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIG 180
Query: 181 LLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTL 240
LLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTL
Sbjct: 181 LLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTL 240
Query: 241 PFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALS 300
PFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALS
Sbjct: 241 PFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALS 300
Query: 301 RWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQAN 360
RWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQAN
Sbjct: 301 RWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQAN 360
Query: 361 ILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHP 420
ILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHP
Sbjct: 361 ILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHP 420
Query: 421 LTALPTHVVLFDPLAENISVFLRNYRLLHRIEHAENRQSRTGRSILVYQRLKKGEENAFN 480
LTALPTHVVLFDPLAENISVFLRNYRLLHRIEHAENRQSRTGRSILVYQRLKKGEENAFN
Sbjct: 421 LTALPTHVVLFDPLAENISVFLRNYRLLHRIEHAENRQSRTGRSILVYQRLKKGEENAFN 480
Query: 481 RGPDSGQHEPDVHDHPPLEDLVLANENENLFN 512
RGPDSGQHEPDVHDHPPLEDLVLANENENLFN
Sbjct: 481 RGPDSGQHEPDVHDHPPLEDLVLANENENLFN 512
>ref|NP_061377.1| (NM_018889) phosphatidylinositol glycan, class B; involved in
GPI-anchor biosynthesis [Mus musculus]
dbj|BAA94827.1| (D84436) Pig-b [Mus musculus]
Length = 542
Score = 512 bits (1307), Expect = e-144
Identities = 194/504 (38%), Positives = 277/504 (54%), Gaps = 47/504 (9%)
Query: 5 YVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLI 64
Y+ L +A+R+ + F+VQT +VPDEYWQSLEVAH++ F YGYLTWEW + +R Y YPL+
Sbjct: 51 YLVLFTIALRILNCFLVQTSFVPDEYWQSLEVAHRMVFSYGYLTWEWTERLRGYTYPLIF 110
Query: 65 AGLYKILALLQLDSAHLLVVLPRI-------------------------RKWALFLILVP 99
A +YK+L LL DS L+ +PR+ +W L
Sbjct: 111 ASIYKVLHLLGKDSVQFLIWIPRLGQALLSAVADIRLYSLLKQLENQEVAQWVFLCQLCS 170
Query: 100 WFWFYTGSRTLANTLEASLTTIALSYFPWYG----ESTAYLWPAAICCFLRPTAAVIWLP 155
WF +Y +RTL NT+E SLT +AL Y+P G S Y A+ C +RPTA + W+P
Sbjct: 171 WFTWYCCTRTLTNTMETSLTALALFYYPLEGSRSVNSIKYSLLVALACVVRPTALIPWVP 230
Query: 156 LSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG 215
L H + ++ L L L F+ +G + L + ID + GQ + FLK+N+ N+G
Sbjct: 231 LLFRHFYQEQR-KLHLTLHHFLPVGFITFSLSLIIDRIFFGQWTLVQLNFLKFNVLQNLG 289
Query: 216 SFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSA 275
+FYGSHPWHWY S G P VLG + FI G ++ LL+T+ TL+V S
Sbjct: 290 TFYGSHPWHWYLSQGFPVVLGTHLPFFIHGCFLAPRRLHI------LLLTVLWTLLVYSM 343
Query: 276 VEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQK 335
+ HKEFRF+ P+LP C+ +L+ + + +L+ NV A+Y VHQ+
Sbjct: 344 LGHKEFRFIYPVLPFCMVFCGYSLAHLKTWRKAALS-----FLLLSNVPLAFYTGLVHQR 398
Query: 336 GPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKE 395
G +++M ++++ R A++ +MPCHSTPYYSH+H ++MRFL C P+L K
Sbjct: 399 GTLDVMNHIQKVCP--RGPDPASASVFIMMPCHSTPYYSHVHCPLSMRFLQCPPDLTGKT 456
Query: 396 QYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLR--NYRLLHRIEH 453
QY DEAD F+ +P+ W+ H +LPTH+V F+ L + I+ FL NY H
Sbjct: 457 QYLDEADMFYLNPLRWLQQ--EFHSNASLPTHLVTFNVLEKEINTFLTSGNYERAATFFH 514
Query: 454 AENRQSRTGRSILVYQRLKKGEEN 477
+ RTG I VY+R G N
Sbjct: 515 THWPERRTGSHIHVYERRLPGRVN 538
>gb|AAH17711.1|AAH17711 (BC017711) phosphatidylinositol glycan, class B [Homo sapiens]
Length = 554
Score = 507 bits (1294), Expect = e-142
Identities = 201/505 (39%), Positives = 280/505 (54%), Gaps = 47/505 (9%)
Query: 4 IYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLL 63
IY+ L LA+R+ + F+VQT +VPDEYWQSLEV+H + F YGYLTWEW + +RSY YPL+
Sbjct: 61 IYLLLFTLALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLI 120
Query: 64 IAGLYKILALLQLDSAHLLVVLPRIRK-------------------------WALFLILV 98
A +YKIL LL DS LL+ +PR+ + W F L
Sbjct: 121 FASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLC 180
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYG----ESTAYLWPAAICCFLRPTAAVIWL 154
WF +Y +RTL NT+E LT IAL Y+P G S Y A+ +RPTA ++W
Sbjct: 181 SWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWT 240
Query: 155 PLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNI 214
PL H L+LIL F+ +G + L + ID + GQ + + FLK+N+ N+
Sbjct: 241 PLLFRHFC-QEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNL 299
Query: 215 GSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLS 274
G+FYGSHPWHWYFS G P +LG + FI G K+ + LL+T+ TL+V S
Sbjct: 300 GTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRY------RILLVTVLWTLLVYS 353
Query: 275 AVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQ 334
+ HKEFRF+ P+LP C+ +L+ + + + N+ A Y VHQ
Sbjct: 354 MLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALS-----FLFLSNLFLALYTGLVHQ 408
Query: 335 KGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKK 394
+G +++M ++++ Y + + A+I +MPCHSTPYYSH+H + MRFL C P+L K
Sbjct: 409 RGTLDVMSHIQKVC--YNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGK 466
Query: 395 EQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFL--RNYRLLHRIE 452
Y DEAD F+ +P++W SH H +LPTH++ F L E IS FL NY+
Sbjct: 467 SHYLDEADVFYLNPLNW--SHREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFF 524
Query: 453 HAENRQSRTGRSILVYQRLKKGEEN 477
H + R G I VY+R KG+ N
Sbjct: 525 HTHLPEGRIGSHIYVYERKLKGKFN 549
>ref|NP_004846.1| (NM_004855) phosphatidylinositol glycan, class B [Homo sapiens]
pir||S71751 dolichyl-phosphate-mannose--glycolipid alpha-mannosyltransferase
(EC 2.4.1.130) PIGB - human
dbj|BAA07709.1| (D42138) PIG-B [Homo sapiens]
Length = 554
Score = 503 bits (1284), Expect = e-141
Identities = 199/505 (39%), Positives = 279/505 (54%), Gaps = 47/505 (9%)
Query: 4 IYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLL 63
IY+ L +A+R+ + F+VQT +VPDEYWQSLEV+H + F YGYLTWEW + +RSY YPL+
Sbjct: 61 IYLLLFTIALRILNCFLVQTSFVPDEYWQSLEVSHHMVFNYGYLTWEWTERLRSYTYPLI 120
Query: 64 IAGLYKILALLQLDSAHLLVVLPRIRK-------------------------WALFLILV 98
A +YKIL LL DS LL+ +PR+ + W F L
Sbjct: 121 FASIYKILHLLGKDSVQLLIWIPRLAQALLSAVADVRLYSLMKQLENQEVARWVFFCQLC 180
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYG----ESTAYLWPAAICCFLRPTAAVIWL 154
WF +Y +RTL NT+E LT IAL Y+P G S Y A+ +RPTA ++W
Sbjct: 181 SWFTWYCCTRTLTNTMETVLTIIALFYYPLEGSKSMNSVKYSSLVALAFIIRPTAVILWT 240
Query: 155 PLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNI 214
PL H L+LIL F+ +G + L + ID + GQ + + FLK+N+ N
Sbjct: 241 PLLFRHFC-QEPRKLDLILHHFLPVGFVTLSLSLMIDRIFFGQWTLVQFNFLKFNVLQNW 299
Query: 215 GSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLS 274
G+FYGSHPWHWYFS G P +LG + FI G K+ + LL+T+ TL+V S
Sbjct: 300 GTFYGSHPWHWYFSQGFPVILGTHLPFFIHGCYLAPKRY------RILLVTVLWTLLVYS 353
Query: 275 AVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQ 334
+ HKEFRF+ P+LP C+ +L+ + + + N+ A Y VHQ
Sbjct: 354 MLSHKEFRFIYPVLPFCMVFCGYSLTHLKTWKKPALS-----FLFLSNLFLALYTGLVHQ 408
Query: 335 KGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKK 394
+G +++M ++++ Y + + A+I +MPCHSTPYYSH+H + MRFL C P+L K
Sbjct: 409 RGTLDVMSHIQKVC--YNNPNKSSASIFIMMPCHSTPYYSHVHCPLPMRFLQCPPDLTGK 466
Query: 395 EQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFL--RNYRLLHRIE 452
Y DEAD F+ +P++W+ H H +LPTH++ F L E IS FL NY+
Sbjct: 467 SHYLDEADVFYLNPLNWL--HREFHDDASLPTHLITFSILEEEISAFLISSNYKRTAVFF 524
Query: 453 HAENRQSRTGRSILVYQRLKKGEEN 477
H + R G I VY+R KG+ N
Sbjct: 525 HTHLPEGRIGSHIYVYERKLKGKFN 549
>ref|NP_568305.1| (NM_121489) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase -like protein [Arabidopsis
thaliana]
gb|AAK91470.1| (AY050456) AT5g14850/T9L3_150 [Arabidopsis thaliana]
Length = 548
Score = 493 bits (1257), Expect = e-138
Identities = 175/517 (33%), Positives = 271/517 (51%), Gaps = 73/517 (14%)
Query: 6 VFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIA 65
+FL LA R+ + ++QTY+ PDE+WQSLEVAH+ FGYGY+TWEW +GIRSY++P+L A
Sbjct: 41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFA 100
Query: 66 GLYKILALLQLDSAHLLVVLPRIRK-------------------------WALFLILVPW 100
LYK+L + LD+ ++++ PR+ + W+LF + W
Sbjct: 101 FLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSLFCQMANW 160
Query: 101 FWFYTGSRTLANTLEASLTTIALSYFPWYGESTA--------YLWPAAICCFLRPTAAVI 152
F F+ +RT +N LE LT + L Y+P +S+ L AA+ C +RPT+AVI
Sbjct: 161 FIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVI 220
Query: 153 WLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFN 212
WL + + L + N ++ I+ + IG LV G +D +G ++ P FLK+N +
Sbjct: 221 WLYVGMLELFLT-PNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLS 279
Query: 213 NIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVV 272
+ G +YG+HPWHWYF+ G +L T I G++ +++L I L +
Sbjct: 280 SGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGII--------KSKNQKLSALILWVLAI 331
Query: 273 LSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRAS--------------------STMLW 312
S + HKEFRFV P+LP+ L A ++ + S S L
Sbjct: 332 YSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLR 391
Query: 313 TTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPY 372
+ +L N+ A Y+S HQ+G + M L + A + R +ILFLMPCHSTPY
Sbjct: 392 LSVYFLLATNIPMALYMSLFHQRGTEDAMNYLSDEAYKGR-----VKSILFLMPCHSTPY 446
Query: 373 YSHIHQNVTMRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFD 432
YS +H+N+ M+FL C P+ EK E DE+D+F +P+ + + + P+H+VLF
Sbjct: 447 YSTLHRNIPMQFLDCTPSAEKGE--LDESDQFLVNPLGFASEL--ARNWSEPPSHIVLFA 502
Query: 433 PLAENISVFL--RNYRLLHRIEHAENRQSRTGRSILV 467
+ F+ +++ + R HA + R +S +V
Sbjct: 503 SEETKLRDFMIQHSFKEVRRFFHAHFKVDRDLQSSVV 539
>pir||T51430 dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein - Arabidopsis
thaliana
emb|CAC01884.1| (AL391149) dolichyl-phosphate-mannose--glycolipid
alpha-mannosyltransferase-like protein [Arabidopsis
thaliana]
Length = 498
Score = 469 bits (1196), Expect = e-131
Identities = 164/479 (34%), Positives = 254/479 (52%), Gaps = 52/479 (10%)
Query: 6 VFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIA 65
+FL LA R+ + ++QTY+ PDE+WQSLEVAH+ FGYGY+TWEW +GIRSY++P+L A
Sbjct: 41 IFLFCLAFRVVNALLIQTYFNPDEHWQSLEVAHRTIFGYGYMTWEWKRGIRSYLHPMLFA 100
Query: 66 GLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLAN--TLEASLTTIAL 123
LYK+L + LD+ ++++ PR+ + I + + + + N T LT + L
Sbjct: 101 FLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDALYGGNVATWSTVLTIMGL 160
Query: 124 SYFPWYGESTA--------YLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKR 175
Y+P +S+ L AA+ C +RPT+AVIWL + + L + N ++ I+
Sbjct: 161 YYWPCIRDSSIDYPVNRKWGLVIAALACAIRPTSAVIWLYVGMLELFLT-PNKVKFIILE 219
Query: 176 FVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVL 235
+ IG LV G +D +G ++ P FLK+N ++ G +YG+HPWHWYF+ G +L
Sbjct: 220 VIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVML 279
Query: 236 GINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVI 295
T I G++ +++L I L + S + HKEFRFV P+LP+ L
Sbjct: 280 FTFTPFSIAGII--------KSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFS 331
Query: 296 TDALSRWSIRAS--------------------STMLWTTALVILVGNVMPAWYLSTVHQK 335
A ++ + S S L + +L N+ A Y+S HQ+
Sbjct: 332 GYAFAQMEVSGSSSSSSVTKKKQVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHQR 391
Query: 336 GPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLEKKE 395
G + M L + A + R +ILFLMPCHSTPYYS +H+N+ M+FL C P+ EK E
Sbjct: 392 GTEDAMNYLSDEAYKGR-----VKSILFLMPCHSTPYYSTLHRNIPMQFLDCTPSAEKGE 446
Query: 396 QYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLRNYRLLHRIEHA 454
DE+D+F +P+ + + + P+H+VLF LR++ + H + A
Sbjct: 447 --LDESDQFLVNPLGFASEL--ARNWSEPPSHIVLFASEE----TKLRDFMIQHSFKEA 497
>dbj|BAB32949.1| (AP002908) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
dbj|BAB84454.1| (AP003546) putative glycolipid alpha-mannosyltransferase [Oryza
sativa]
Length = 506
Score = 395 bits (1006), Expect = e-109
Identities = 158/472 (33%), Positives = 242/472 (50%), Gaps = 54/472 (11%)
Query: 6 VFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIA 65
V L LA R A+ +V+TY+ PDE+WQ LEVAH++ FGYG+LTWEW +G+RSY++P + A
Sbjct: 48 VLALALAFRAANALLVRTYFNPDEHWQCLEVAHRIVFGYGHLTWEWKRGLRSYLHPFIFA 107
Query: 66 GLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTLANT----LEASLTTI 121
LYKIL+LL LDS + + PR+ + + Y S+ + N +E LT
Sbjct: 108 ALYKILSLLHLDSPWFMAMAPRLLQSVFASFGD--LYLYKLSKLIFNNHVAHMETVLTVT 165
Query: 122 ALSYF-----PWYGESTAYLWPAA----------------ICCFLRPTAAVIWLPLSLYH 160
L Y+ G S AA + C +RPT+A+ WL + L
Sbjct: 166 GLYYWFVAIESVKGNSVVSKQQAASKQSPPSRKMALLIAALACAIRPTSAITWLYVGLLD 225
Query: 161 LRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGS 220
+ + I V +G+ V + +D + +G I+ P FLK+N+F++ G +YG+
Sbjct: 226 FIQMKSKSR-FIFLEVVPLGVFVLAVTTFLDCWMYGSRIIVPLNFLKFNLFSSGGDYYGT 284
Query: 221 HPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKE 280
H +HWYFS G P+++ I G++++ + L I LVV S + HKE
Sbjct: 285 HVFHWYFSQGFPSMIWTFLPFSISGILKSREWR--------LAGLIVWVLVVYSILGHKE 336
Query: 281 FRFVSPLLPLCLYVITDALSRWSIRASS--------TMLWTTALVILVGNVMPAWYLSTV 332
FRFV P+LP L+ + + L + +++++ NV A Y+S
Sbjct: 337 FRFVLPVLPFMFMFSGHNLAAMAQLKGKGHNEKGRLSRLKLSVILLILTNVPMALYMSLY 396
Query: 333 HQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRFLTCEPNLE 392
HQ+G + M L A + R ++LFLMPCHSTPYYS +H N+ MRFL C P+
Sbjct: 397 HQRGTEDAMLYLSREAHDGR-----VKSVLFLMPCHSTPYYSTLHYNLPMRFLDCTPSEN 451
Query: 393 KKEQYKDEADRFFEDPVHWINSHIPMHPLTALPTHVVLFDPLAENISVFLRN 444
K DE+DRF +P ++ L++ +H+VLF+ ++ + LRN
Sbjct: 452 KGT--LDESDRFLMNPADFVGE--VFGNLSSF-SHIVLFESEERHVKLLLRN 498
>pir||T41079 probable alpha 1,2 mannosyltransferase - fission yeast
(Schizosaccharomyces pombe)
emb|CAB53078.1| (AL109957) putative alpha 1,2 mannosyltransferase
[Schizosaccharomyces pombe]
Length = 506
Score = 376 bits (956), Expect = e-103
Identities = 144/536 (26%), Positives = 239/536 (43%), Gaps = 100/536 (18%)
Query: 4 IYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLL 63
I+ +L IL R + V+T++ PDE++QSLEVAH F YG+LTWEW IRS ++PL+
Sbjct: 3 IWFWLAILVFRWWNALWVKTFFQPDEFYQSLEVAHHFIFRYGFLTWEWTSAIRSALHPLI 62
Query: 64 IAGLYKILALLQLDSAHLLV--------------------------VLPRIRKWALFLIL 97
A LY++L +L+LDS++ + + W L L
Sbjct: 63 FAALYRVLQVLKLDSSYFVFTNAPKLLQGTFAAILDYGTYKFALVRYGSKTANWTLACSL 122
Query: 98 VPWFWFYTGSRTLANTLEASLTTIALSYFPWYGES---------------TAYLWPAAIC 142
V Y G RT +N+LE +LT+I YF +Y + ++ AA
Sbjct: 123 VSIMNAYVGVRTFSNSLETTLTSIGFYYFSYYLKYENSSPEQRKKAYSSLLGFISVAAFA 182
Query: 143 CFLRPTAAVIWLPLSLYHLRRSRQNVLEL-----ILKRFVLIGLLVAG------------ 185
CF+RPT ++W+ L+ + + + +L + RF + L G
Sbjct: 183 CFIRPTNILVWIFPLLFWNKNPQTPIKDLLSFSNVFNRFRFLYALGYGRLFGIFVLCVSL 242
Query: 186 --LGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFI 243
+ I D +G+ + F ++N+ + + S YG + WH+Y S LP + G +
Sbjct: 243 FLVNIIADRILYGRFVFPIISFFQFNVTSGLSSLYGLNAWHYYLSQALPLICGGFLPFVL 302
Query: 244 FGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWS 303
+ Q TI S + HKE RFV P+ P+ L + S +S
Sbjct: 303 LTMD------------LQTAGTILCVFFPYSLIGHKELRFVYPISPILLTLAGKFFSSFS 350
Query: 304 IRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILF 363
+ +I +G+ + +L HQ G +E+MP + +A + L
Sbjct: 351 SWKRAARF---FFLIGLGHALVITFLCRFHQFGVMEVMPLIHSLAEKN-------QTGLI 400
Query: 364 LMPCHSTPYYSHIHQNVT---MRFLTCEPNLEKKEQYKDEADRFFEDPVHWINSHIPMHP 420
L PCH+TP+ SHIH +FLTCEP E+ DE DRF+E+ +++
Sbjct: 401 LAPCHTTPWQSHIHSPFAENGWKFLTCEPF----EKPFDETDRFYENMPTFLDK------ 450
Query: 421 LTALPTHVVLFDPLAENISVFLRN----YRLLHRIEHAENRQSRT-GRSILVYQRL 471
+ P +++ F+ ++ +L + Y + R ++ +SR ++LVY++L
Sbjct: 451 IKEWPDYLIFFEERFYSLYSYLDSRGLKYEEVQRYYNSLIPESRERAGALLVYKKL 506
>ref|NP_011373.1| (NC_001139) Involved in glycosyl phosphatidyl inositol synthesis;
could be the target of the GPI synthesis inhibitor,
YW3548; Most likely an alpha 1,2 mannosyltransferase
utilized for the addition of the third mannose onto the
GPI core structure.; Gpi1>
sp|P30777|YGO2_YEAST Hypothetical 72.6 kDa protein in MRF1-HUL5 intergenic region
pir||S64156 probable membrane protein YGL142c - yeast (Saccharomyces
cerevisiae)
emb|CAA96854.1| (Z72664) ORF YGL142c [Saccharomyces cerevisiae]
emb|CAA68220.1| (X99960) putative, YGL142c [Saccharomyces cerevisiae]
Length = 616
Score = 320 bits (812), Expect = 6e-86
Identities = 139/531 (26%), Positives = 230/531 (43%), Gaps = 76/531 (14%)
Query: 2 KLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYP 61
++ + L+L + S ++ +Y S +VA L +T + Y
Sbjct: 86 SILLHYALLLLSTIGSDLLILLL---PKYELSWQVAEDLKRLPFDVTRSFEYYGVIYAPK 142
Query: 62 LLIAGLYKI-----------LALLQLDSAHLLVV------LPRIRKWALFLILVPWFWFY 104
+++A L I L LL LD + L I K+AL L L +F +
Sbjct: 143 IVMAVLASIGEYYIVRFVQKLYLLTLDKRNEKEEEERRSGLSEITKFALLLSLTNFFNCF 202
Query: 105 TGSRTLANTLEASLTTIALSYFPWYG-------ESTAYLWPAAICCFLRPTAAVIW---- 153
+RT N+ E LT+IAL Y+ W G T L A + C RP++ +IW
Sbjct: 203 FITRTFINSFEMILTSIALYYWDWTGGQMIKESSFTKSLIFAFLACLQRPSSGLIWVIPS 262
Query: 154 LPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNN 213
+ L L + + + ++L + + + LV ID Y++ ++ + FLK+N
Sbjct: 263 ISLILNLVGKKQYHLLFITFSKVLRSFFLVFTANAIIDMYFYEKVTFPFFRFLKFNFTTP 322
Query: 214 IGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEK----YPVSKQLLITIFLT 269
+ FYG PWH++F LP VLG + F FG+ + K Q+ +TI L
Sbjct: 323 LSKFYGVAPWHFHFFQSLPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLN 382
Query: 270 LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRW--SIRASSTMLWTTALVILVGNVMPAW 327
L+V S + HKEFRF+ PL PL + + + L R + L + ++ +V A
Sbjct: 383 LLVYSTLPHKEFRFIFPLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIAL 442
Query: 328 YLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRF--L 385
L T H+ G IE+M ++ E ++ F+MPCHSTP S++H++ +
Sbjct: 443 LLDTFHESGSIEVM--------KFLHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQDLWSI 494
Query: 386 TCEPNLE---------KKEQYKDEADRFFEDPVHWINSHIPMHPLT-----------ALP 425
TC P L K E Y DE+D ++D +I + P P
Sbjct: 495 TCNPPLHLLGDPEAYSKLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWP 554
Query: 426 THVVLFDPLAENI-------SVFLRNYRLLHRIEHAENRQSRTGRSILVYQ 469
T++V+F+ + S ++ R + + H ++R R+G I+ Y+
Sbjct: 555 TYLVVFEHMENAFLKDFLKDSSYIEYNRFFNSLAHWDSR--RSGDIIIYYK 603
Score = 80.9 bits (198), Expect = 4e-14
Identities = 28/68 (41%), Positives = 47/68 (68%)
Query: 6 VFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIA 65
+F + LA R+ + + +T++ DE+WQ+LE AH F YG LTWEW G+RSY++P++
Sbjct: 17 IFWVFLAFRVLNAVLTRTFFQADEFWQALEPAHWKAFKYGELTWEWKFGVRSYLFPMIFE 76
Query: 66 GLYKILAL 73
Y++++L
Sbjct: 77 LTYRLVSL 84
>gb|AAF54441.1| (AE003684) CG8412 gene product [Drosophila melanogaster]
gb|AAL48754.1| (AY071132) RE17513p [Drosophila melanogaster]
Length = 678
Score = 309 bits (784), Expect = 9e-83
Identities = 75/416 (18%), Positives = 157/416 (37%), Gaps = 60/416 (14%)
Query: 10 ILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTF------GYGYLTWEWVQGIRSYVYPLL 63
IL A+ +V T + E +L+ H + + Y + + V R+++ PL+
Sbjct: 3 ILIFVTAAAHLVYTPFTKVEESFNLQAMHDILYLRNNFTQYDHHDYPGVVP-RTFIGPLV 61
Query: 64 IAGL-------------------YKIL---------ALLQLDSAHLLVVLPRIRKWALFL 95
++ + Y + A L A + +R W +
Sbjct: 62 VSIISAPFVLLFETLSINKFWAQYVVRLVLAGAISVAWNSLRQAVTKIYGVEVRLWFTAI 121
Query: 96 ILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLP 155
+ + + + +R L N + A++Y+ + ++ + I + + ++L
Sbjct: 122 TITQFHFMFYMTRPLPNIFALPIVLFAIAYWLR-DQHKPFIICSGISILVFRSELALFLG 180
Query: 156 LSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG 215
+ L R+ ++ +LK + G+ + + +D+++ +L+ E L YN N
Sbjct: 181 ILLVVSLLRRKVSIDGLLKVALPAGVCILAATVLVDSFFWRRLLWPEGEVLWYNTVLNKS 240
Query: 216 SFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSA 275
S +G+ P+ WYF LP +G + + GV P + L+++ L +++ S
Sbjct: 241 SNWGTSPFLWYFYSALPRAMGASLVLVPIGV-------ALEPRIRPLVLSALLFVLLYSI 293
Query: 276 VEHKEFRFVSPLLPLCLYVITDALSR-WSIRASSTMLWTTALVI-----LVGNVMPAWYL 329
+ HKE RF+ + P+ A R W A ST W + L + L+ NV +L
Sbjct: 294 LPHKELRFIIYVFPVLNIAAACACQRIWMNSAKST--WHSFLALACGAHLLLNVFITLFL 351
Query: 330 ---STVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTM 382
S + G + +L + + ++ + + N
Sbjct: 352 LVISGTNYPGG-AALSRLHRL-----EAGTSNVSVHISNLAAQSGVSRFMEINNEW 401
>emb|CAD22101.1| (AJ429133) putative mannosyltransferase [Mus musculus]
Length = 483
Score = 300 bits (761), Expect = 4e-80
Identities = 86/416 (20%), Positives = 159/416 (37%), Gaps = 55/416 (13%)
Query: 8 LLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTF------GYGYLTWEWVQGIRSYVYP 61
LL L V +A++ +V Y E +L+ H L + Y + + V R+++ P
Sbjct: 14 LLGLLVTVATIHLVICPYTKVEESFNLQATHDLLYHQLDIDKYDHHEFPGVVP-RTFLGP 72
Query: 62 LLIAGLYK----ILALLQLDSAH----------------LLVVLPRIRKWALFLILVPWF 101
L+IA +L+LL++ + L + +R+ + V +
Sbjct: 73 LVIAAFSSPVVYVLSLLEVSKFYSQLIVRGVLGLGVISGLWTLQKEVRQQFGATVAVMFC 132
Query: 102 W--------FYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIW 153
W + +RTL N L ++ AL+ + ++W +A +
Sbjct: 133 WISATQFHLMFYCTRTLPNVLALAVVLPALTAW-LQRRWALFVWLSAFVIIGFRAELAML 191
Query: 154 LPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNN 213
L ++L R+ + +L+ + GLL GL +A+D+Y+ L+ L YN N
Sbjct: 192 LGIALLLTLYQRRLTVARVLRHAIPAGLLCLGLTVAVDSYFWRYLVWPEGVVLGYNTVLN 251
Query: 214 IGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVL 273
S +G+ P WYF LP LG + L G ++ + L + + +
Sbjct: 252 KSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGAVDRRTYA--------LALPSLGFVALY 303
Query: 274 SAVEHKEFRFVSPLLPLCLYVITDALSRWSIRAS-----STMLWTTALVILVGNVMPAWY 328
S + HKE RF+ P+ + + + S ML T +++ V + Y
Sbjct: 304 SLLPHKELRFIIYTFPVLNIMAARGCTYILNKKSWPYKVRAMLVTGHILVNVAYTATSLY 363
Query: 329 LSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRF 384
+S + G + M +L E+ D + + T + N R+
Sbjct: 364 VSHFNYPGGV-AMQQLHELVPPQTD-----VLLHIDVAAAQTGVSRFLQVNDDWRY 413
>gb|AAH21791.1|AAH21791 (BC021791) Similar to disrupted in bipolar disorder 1 [Mus
musculus]
Length = 611
Score = 286 bits (726), Expect = 6e-76
Identities = 83/333 (24%), Positives = 136/333 (39%), Gaps = 41/333 (12%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEW--VQGIRSYVYPLLI 64
F +L+ RL + + DE + E H L +G G+ TWE+ V IRSY Y LL
Sbjct: 62 FKCLLSARLCAALLSNISD-CDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLH 120
Query: 65 AG----------------LYKILALLQLDSAH--LLVVLPRIRKWAL--------FLILV 98
A Y + LL S L +K+ L FL+L
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLS 180
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSL 158
F + S L ++ T IA++ + A L AA P +A + LP++
Sbjct: 181 TGM-FCSSSAFLPSSFCMYTTLIAMTGWYMDKTPIAVLGVAAGAILGWPFSAALGLPIAF 239
Query: 159 YHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG-SF 217
L R++ + L ++ L + ID+Y++G+L+V P + YN+F + G
Sbjct: 240 DLLA--RKHRWKSFLLWSLVALALFLVPVVVIDSYYYGKLVVAPLNIVLYNVFTSHGPDL 297
Query: 218 YGSHPWHWYFSVGLP-----TVLGINTLPFIFGVMETVKKSEKYPVSKQLLI---TIFLT 269
YG+ PW++Y G L + LP F + +++ + + +++
Sbjct: 298 YGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIW 357
Query: 270 LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRW 302
++ HKE RF+ P+ PL ALS
Sbjct: 358 FIIFFIQPHKEERFLFPVYPLICLCGAVALSAL 390
>emb|CAB66861.1| (AL136927) hypothetical protein [Homo sapiens]
Length = 611
Score = 285 bits (724), Expect = 9e-76
Identities = 79/333 (23%), Positives = 133/333 (39%), Gaps = 41/333 (12%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLLI 64
F +L+ RL + + DE + E H L +G G+ TWE+ IRSY Y LL
Sbjct: 62 FKCLLSARLCAALLSNISD-CDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 65 AG----------------LYKILALLQLDSAH--LLVVLPRIRKWAL--------FLILV 98
A Y + LL S L +K+ L FL+L
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSL 158
F + S L ++ T IA++ + S A L AA P +A + LP++
Sbjct: 181 TGM-FCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAF 239
Query: 159 YHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG-SF 217
L ++ + ++ +L + ID+Y++G+L++ P + YN+F G
Sbjct: 240 DLLVM--KHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDL 297
Query: 218 YGSHPWHWYFSVGLP-----TVLGINTLPFIFGVMETVKKSEKYPVSKQLLI---TIFLT 269
YG+ PW++Y G L + LP + +++ + + +++
Sbjct: 298 YGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIW 357
Query: 270 LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRW 302
++ HKE RF+ P+ PL ALS
Sbjct: 358 FIIFFIQPHKEERFLFPVYPLICLCGAVALSAL 390
>gb|AAH09255.1|AAH09255 (BC009255) hypothetical protein FLJ21845 [Homo sapiens]
Length = 618
Score = 284 bits (721), Expect = 3e-75
Identities = 79/333 (23%), Positives = 133/333 (39%), Gaps = 41/333 (12%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLLI 64
F +L+ RL + + DE + E H L +G G+ TWE+ IRSY Y LL
Sbjct: 62 FKCLLSARLCAALLSNISD-CDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 65 AG----------------LYKILALLQLDSAH--LLVVLPRIRKWAL--------FLILV 98
A Y + LL S L +K+ L FL+L
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSL 158
F + S L ++ T IA++ + S A L AA P +A + LP++
Sbjct: 181 TGM-FCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAF 239
Query: 159 YHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG-SF 217
L ++ + ++ +L + ID+Y++G+L++ P + YN+F G
Sbjct: 240 DLLVM--KHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDL 297
Query: 218 YGSHPWHWYFSVGLP-----TVLGINTLPFIFGVMETVKKSEKYPVSKQLLI---TIFLT 269
YG+ PW++Y G L + LP + +++ + + +++
Sbjct: 298 YGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIW 357
Query: 270 LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRW 302
++ HKE RF+ P+ PL ALS
Sbjct: 358 FIIFFIQPHKEERFLFPVYPLICLCGAVALSAL 390
>gb|AAL25798.1| (AF395532) DIBD1 [Homo sapiens]
Length = 611
Score = 283 bits (719), Expect = 4e-75
Identities = 79/333 (23%), Positives = 133/333 (39%), Gaps = 41/333 (12%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLLI 64
F +L+ RL + + DE + E H L +G G+ TWE+ IRSY Y LL
Sbjct: 62 FKCLLSARLCAALLSNISD-CDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 65 AG----------------LYKILALLQLDSAH--LLVVLPRIRKWAL--------FLILV 98
A Y + LL S L +K+ L FL+L
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSL 158
F + S L ++ T IA++ + S A L AA P +A + LP++
Sbjct: 181 TGM-FCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAF 239
Query: 159 YHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG-SF 217
L ++ + ++ +L + ID+Y++G+L++ P + YN+F G
Sbjct: 240 DLLVM--KHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTPHGPDL 297
Query: 218 YGSHPWHWYFSVGLP-----TVLGINTLPFIFGVMETVKKSEKYPVSKQLLI---TIFLT 269
YG+ PW++Y G L + LP + +++ + + +++
Sbjct: 298 YGTEPWYFYLIKGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIW 357
Query: 270 LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRW 302
++ HKE RF+ P+ PL ALS
Sbjct: 358 FIIFFIQPHKEERFLFPVYPLICLCGAVALSAL 390
>ref|NP_079016.1| (NM_024740) disrupted in bipolar disorder 1; similar to putative
mannosyltransferase Alg9p (S. cerevisiae) [Homo sapiens]
dbj|BAB15154.1| (AK025498) unnamed protein product [Homo sapiens]
Length = 618
Score = 283 bits (717), Expect = 8e-75
Identities = 80/333 (24%), Positives = 133/333 (39%), Gaps = 41/333 (12%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLLI 64
F +L+ RL + + DE + E H L +G G+ TWE+ IRSY Y LL
Sbjct: 62 FKCLLSARLCAALLSNISD-CDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 65 AG----------------LYKILALLQLDSAH--LLVVLPRIRKWAL--------FLILV 98
A Y + LL S L +K+ L FL+L
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSL 158
F + S L ++ T IA++ + S A L AA P +A + LP++
Sbjct: 181 TGM-FCSSSAFLPSSFCMYTTLIAMTGWYMDKTSIAVLGVAAGAILGWPFSAALGLPIAF 239
Query: 159 YHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG-SF 217
L ++ + ++ +L + ID+Y++G+L++ P + YNIF G
Sbjct: 240 DLLVM--KHRWKSFFHWSLMALILFLVPVVVIDSYYYGKLVIAPLNIVLYNIFTPHGPDL 297
Query: 218 YGSHPWHWYFSVGLP-----TVLGINTLPFIFGVMETVKKSEKYPVSKQLLI---TIFLT 269
YG+ PW++Y G L + LP + +++ + + +++
Sbjct: 298 YGTEPWYFYLINGFLNFNVAFALALLVLPLTSLMEYLLQRFHVQNLGHPYWLTLAPMYIW 357
Query: 270 LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRW 302
++ HKE RF+ P+ PL ALS
Sbjct: 358 FIIFFIQPHKEERFLFPVYPLICLCGAVALSAL 390
>ref|NP_077010.1| (NM_024105) hypothetical protein MGC3136 [Homo sapiens]
gb|AAH01729.1|AAH01729 (BC001729) Unknown (protein for MGC:3136) [Homo sapiens]
emb|CAC67488.1| (AJ303120) putative alpha mannosyltransferase [Homo sapiens]
gb|AAL55850.1|AF318343_1 (AF318343) unknown [Homo sapiens]
Length = 488
Score = 274 bits (694), Expect = 4e-72
Identities = 89/419 (21%), Positives = 163/419 (38%), Gaps = 57/419 (13%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTF------GYGYLTWEWVQGIRSYVY 60
LL L V +A+V +V Y E +L+ H L + Y +L + V R+++
Sbjct: 12 LLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFPGVVP-RTFLG 70
Query: 61 PLLIAGLYK----ILALLQLDSAH----------------LLVVLPRIRKWALFLILVPW 100
P++IA +L+LL++ + L + +R+ ++ +
Sbjct: 71 PVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMF 130
Query: 101 FW--------FYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVI 152
W + +RTL N L + +AL+ + + E ++W +A + +
Sbjct: 131 CWVTAMQFHLMFYCTRTLPNVLALPVVLLALAAWLRH-EWARFIWLSAFAIIVFRVELCL 189
Query: 153 WLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFN 212
+L L L +R+ + L+ V G+L GL +A+D+Y+ QL + L YN
Sbjct: 190 FLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVL 249
Query: 213 NIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVV 272
N S +G+ P WYF LP LG + L G+++ + + +L F+ +
Sbjct: 250 NKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVD------RRTHAPTVLALGFM--AL 301
Query: 273 LSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASS-------TMLWTTALVILVGNVMP 325
S + HKE RF+ P+ S ++L LV+
Sbjct: 302 YSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSAT 361
Query: 326 AWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRF 384
A Y+S + G + M +L ++ D + + T + N R+
Sbjct: 362 ALYVSHFNYPGGV-AMQRLHQLVPPQTD-----VLLHIDVAAAQTGVSRFLQVNSAWRY 414
>emb|CAC83681.1| (AJ290427) putative dolichyl-p-man: Man7GlcNAc2-PP-dolichyl
mannosyltransferase [Homo sapiens]
Length = 488
Score = 273 bits (692), Expect = 6e-72
Identities = 89/419 (21%), Positives = 162/419 (38%), Gaps = 57/419 (13%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTF------GYGYLTWEWVQGIRSYVY 60
LL L V +A+V +V Y E +L+ H L + Y +L + V R+++
Sbjct: 12 LLLGLLVAVATVHLVICPYTKVEESFNLQATHDLLYHWQDLEQYDHLEFPGVVP-RTFLG 70
Query: 61 PLLIAGLYK----ILALLQLDSAH----------------LLVVLPRIRKWALFLILVPW 100
P++IA +L+LL++ + L + +R+ ++ +
Sbjct: 71 PVVIAVFSSPAVYVLSLLEMSKFYSQLIVRGVLGLGVIFGLWTLQKEVRRHFGAMVATMF 130
Query: 101 FW--------FYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVI 152
W +RTL N L + +AL+ + + E ++W +A + +
Sbjct: 131 CWVTAMQFHLMVYCTRTLPNVLALPVVLLALAAWLRH-EWARFIWLSAFAIIVFRVELCL 189
Query: 153 WLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFN 212
+L L L +R+ + L+ V G+L GL +A+D+Y+ QL + L YN
Sbjct: 190 FLGLLLLLALGNRKVSVVRALRHAVPAGILCLGLTVAVDSYFWRQLTWPEGKVLWYNTVL 249
Query: 213 NIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVV 272
N S +G+ P WYF LP LG + L G+++ + + +L F+ +
Sbjct: 250 NKSSNWGTSPLLWYFYSALPRGLGCSLLFIPLGLVD------RRTHAPTVLALGFM--AL 301
Query: 273 LSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASS-------TMLWTTALVILVGNVMP 325
S + HKE RF+ P+ S ++L LV+
Sbjct: 302 YSLLPHKELRFIIYAFPMLNITAARGCSYLLNNYKKSWLYKAGSLLVIGHLVVNAAYSAT 361
Query: 326 AWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRF 384
A Y+S + G + M +L ++ D + + T + N R+
Sbjct: 362 ALYVSHFNYPGGV-AMQRLHQLVPPQTD-----VLLHIDVAAAQTGVSRFLQVNSAWRY 414
>ref|NP_505071.1| (NM_072670) ZC513.5.p [Caenorhabditis elegans]
gb|AAC48267.3| (U53155) Hypothetical protein ZC513.5 [Caenorhabditis elegans]
Length = 492
Score = 269 bits (683), Expect = 6e-71
Identities = 77/413 (18%), Positives = 147/413 (34%), Gaps = 58/413 (14%)
Query: 15 LASVFVVQTYYVPDEYWQSLEVAHKLTF-------GYGYLTWEWVQGIRSYVYPLLIAGL 67
+ + ++ E +++ H L F Y + + V R+++ P+ +A L
Sbjct: 11 VTIIHIILAPGTKVEESFNVQATHDLMFHLPTNLSNYDHSQFPGVVP-RTFIGPISLAIL 69
Query: 68 YK-------------------ILALLQLDS--AHLLVVLPRIRKWA------LFLILV-P 99
I A L L + A L RK+ L LI+
Sbjct: 70 SSPMSFIFRFWAIPKMWQLLLIRATLGLMNAMAFLYFARSVNRKFGRETAMYLRLIMCTQ 129
Query: 100 WFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPLSLY 159
+ + + SR L NT L I + G + + A L V+
Sbjct: 130 FHYIFYMSRPLPNTFALILVMI-VFERLLEGRYESAVRYATASVILFRCELVLLYGPIFL 188
Query: 160 ---HLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGS 216
R + + + V I + + I ID+Y+ G+ + E + +N+ N
Sbjct: 189 GYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPIDSYFWGRPLWPEGEVMFFNVVENRSH 248
Query: 217 FYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAV 276
YG+ P+ WYF LP L TL G++ + Q+++ + + + S +
Sbjct: 249 EYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRRL-------PQIVLPSVIFIFLYSFL 301
Query: 277 EHKEFRFVSPLLPLCLYVITDALSRWSIRASST----MLWTTALVILVGNV---MPAWYL 329
HKE RF+ +LP+ +R I + +L+ ++ L+ NV +
Sbjct: 302 PHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFFRMILFFGVILHLLANVLCTGMFLLV 361
Query: 330 STVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTM 382
++ + G + + L+ + R + + + C T +H N
Sbjct: 362 ASKNYPG-FDALNYLQ---FQNRFDAKKPVTVYIDNACAQTGVNRFLHINDAW 410
>dbj|BAA94863.1| (AB033824) GPI anchor biosynthesis protein [Trypanosoma brucei]
Length = 558
Score = 261 bits (661), Expect = 3e-68
Identities = 89/313 (28%), Positives = 158/313 (50%), Gaps = 23/313 (7%)
Query: 92 ALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAV 151
AL L L W+ Y G R N +EA L + L +L + +R T+AV
Sbjct: 153 ALLLSLSNWYMAYCGVRLYGNVIEALLVLLTL----QQRRYVPFLLLTGLASAIRVTSAV 208
Query: 152 IWLPLSLYHLRR-SRQNVLELILKRFVLIGLL----VAGLGIAIDTYWHGQLIVTPYEFL 206
+ PL HL +R++ L R VL GL+ V G + +D ++G+ ++TP F
Sbjct: 209 VLSPLVFRHLANATREHGFIRGLFRIVLTGLIVLVAVLGGVMVLDYCFYGRWVLTPLAFF 268
Query: 207 KYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITI 266
++N+ +N+ F+G HPW++Y L ++G + L I + + + VS+ +L +
Sbjct: 269 RFNVLHNLSRFFGEHPWYFYVGPVLVGIVGPHVLFTIAAPLVLWRDTASRAVSRPVLGML 328
Query: 267 ---FLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNV 323
TL S ++HKE RFV ++PL L L RWS R S+ ++ L +L N+
Sbjct: 329 GIGAWTLGFYSLIDHKEMRFVFVVIPLSLITAAFVLVRWS-RTSAVVVKMNRLFVL-FNI 386
Query: 324 MPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVT-M 382
+ + + V+++GP+++M ++R+ R R + + C++ P YS++H+ V +
Sbjct: 387 VMIYLMGYVYRRGPLDVMAEVRDGPRINR--------LDVIATCYTVPGYSYMHKKVNHL 438
Query: 383 RFLTCEPNLEKKE 395
F+ C +L++K
Sbjct: 439 GFVDCSIDLDEKT 451
Score = 103 bits (256), Expect = 8e-21
Identities = 33/106 (31%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Query: 5 YVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLI 64
++ L RL ++T PDE+WQS EVA+ + FG G+L WEW G+RS ++P ++
Sbjct: 4 WLISLTFIYRLFLCATIRTVEAPDEWWQSTEVAYNMVFGKGHLPWEWRYGLRSVLFPAVV 63
Query: 65 AGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSRTL 110
A + +L LL D+ + PR+ + + ++ + TL
Sbjct: 64 ALPFYLLKLLGRDTTWAVWFAPRVLQALVLTLIDV--SVFCMGATL 107
>ref|XP_081472.1| (XM_081472) CG11851 [Drosophila melanogaster]
gb|AAF56419.1| (AE003751) CG11851 gene product [Drosophila melanogaster]
gb|AAL39788.1| (AY069643) LD40966p [Drosophila melanogaster]
Length = 623
Score = 259 bits (657), Expect = 7e-68
Identities = 95/397 (23%), Positives = 150/397 (36%), Gaps = 63/397 (15%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLL- 63
F ++ RL S DE + E H + G+G TWE+ G+RSY Y LL
Sbjct: 77 FKTFVSARLCSAIWAYIAD-CDETFNYWEPLHYIINGHGLQTWEYSPQFGLRSYTYLLLQ 135
Query: 64 ---------------IAGLYKILALLQLDSAHLLVVLPRI----------RKWALFLILV 98
I Y + +L A + + + R W +F +
Sbjct: 136 GVPGYFYQKLFNPSPILIFYMVRCMLGFGCAVMERYMYKSICQEFGIHIGRLWLIFQLFS 195
Query: 99 PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAI-CCFLRPTAAVIWLPLS 157
F + + L ++ AL+ + W ++ AI P AA+I +PL
Sbjct: 196 VGM-FVSSTALLPSSFSMYFGCAALAAW-WQQNYCFAIFLTAISALLGWPFAALIGIPLV 253
Query: 158 LYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIG-S 216
L L R R + ++ ++ G VA IAIDT + G+L P + YN+F + G +
Sbjct: 254 LEMLLRQRD--WKTFVQWTLISGATVAIPMIAIDTSYFGKLTFAPLNIVWYNVFTSHGPN 311
Query: 217 FYGSHPWHWYFSVGLPTV----LGINTLPFIFGVMETV-----KKSEKYPVSKQLLITIF 267
+G+ P +Y G L LP + + + K + +P L ++
Sbjct: 312 IFGTEPLSYYIINGFLNFNIIWLLALQLPIMLVIDYLIVPAKSKSTLNFPHYISL-APLY 370
Query: 268 LTLVVLSAVEHKEFRFVSPLLPLCLYVIT---DALSRWSIRASSTMLWTT---------- 314
L L+V A HKE RF+ P+ PL D R R S +
Sbjct: 371 LWLLVFFAQPHKEERFLFPIYPLISLCGAITVDVYQRIFFRMKSVVFKIKAGVHYLDHSM 430
Query: 315 ALVILVGNVMPAWYLSTV-----HQKGPIELMPKLRE 346
+ ILV LS V + P++LM +L +
Sbjct: 431 FIAILVMVTSTLLGLSRVFALYRNYHAPMDLMLELNQ 467
>pir||T50116 probable mannosyltransferase involved in N-glycosylation [imported]
- fission yeast (Schizosaccharomyces pombe)
emb|CAB75773.1| (AL157734) putative mannosyltransferase involved in N-glycosylation
[Schizosaccharomyces pombe]
Length = 577
Score = 251 bits (637), Expect = 2e-65
Identities = 70/341 (20%), Positives = 128/341 (37%), Gaps = 44/341 (12%)
Query: 1 MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSY 58
+ ++ F ++ +RL S + DE + E H L +GYG TWE+ IRS+
Sbjct: 12 VSFVWTFSILAVLRLTSASF-RVIDDCDEVYNYWEPLHYLLYGYGLQTWEYSPEYAIRSW 70
Query: 59 VYPLLIA---------------GLYKILALLQLDSAH----LLVVLPRIRKWALFLILVP 99
Y L A Y I +L SA L++ + R A+ L L
Sbjct: 71 FYIALHAVPGFLARGLGLSRLHVFYFIRGVLACFSAFCETNLILAVARNFNRAVALHLTS 130
Query: 100 WFWFYT-----GSRTLANTLEASLTTIALSYFP----WYGESTAYLWPAAICCFLRPTAA 150
+ + + L ++ ++ T+ALS + P +A
Sbjct: 131 VLFVNSGMWSASTSFLPSSFAMNMVTLALSAQLSPPSTKRTVKVVSFITIGAVIGWPFSA 190
Query: 151 VIWLPLSLYHLRRSRQNVLELILKRF--VLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKY 208
+ +P L L + L + F + + LL+ G+ I +D+ ++ ++ + +KY
Sbjct: 191 ALSIPFILLELVDLKGRFRHLFCRWFKAIFVALLITGICITVDSLFYHRIQFVAWNIVKY 250
Query: 209 NIFNNIG---SFYGSHPWHWYFSV-------GLPTVLGINTLPFIFGVMETVKKSEKYPV 258
N+ G YG+ PW +YF+ L + L + + +
Sbjct: 251 NVLAKDGRGPDIYGTEPWWYYFANLSLQHNIVLWFAMACGPLVLLAAFTNWINLDSFLDL 310
Query: 259 SKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDAL 299
S ++ ++ L + HKE RF+ P+ P+ L
Sbjct: 311 S-SVISPFYIWLFIFIIQPHKEERFMYPIYPVLCLAAAIGL 350
>pir||T39659 cell wall biosynthesis protein N3265 homolog - fission yeast
(Schizosaccharomyces pombe)
emb|CAA21306.1| (AL031856) putative involvement in cell wall biogenesis and
architecture [Schizosaccharomyces pombe]
Length = 547
Score = 250 bits (634), Expect = 4e-65
Identities = 68/405 (16%), Positives = 128/405 (30%), Gaps = 57/405 (14%)
Query: 2 KLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKL-------TFGYGYLTWEWVQG 54
+ + IL V + +T + E +++ H + + Y +L +
Sbjct: 6 SICWYLANILLVTCIGYYSYKTPFTKVEESFAMQAIHDIQTYRWDLSKVYDHLEFPGAVK 65
Query: 55 IRSYVYPLLIAGLYKILAL--------------------LQLDSAHLLVVLPRIRKWALF 94
RS++ L IA L I + + + +
Sbjct: 66 -RSFIPSLFIAVLSYIPSWFVNPLLAARWTIGYLSWESMNSVSCSISKRFGTLSGALFIL 124
Query: 95 LILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIWL 154
+ Y SR L+N T +LS + + + + L
Sbjct: 125 FSCAQFHLVYYMSRPLSNIFGLIATNHSLSL-LLKNNYYGSISILVFAAAIVRSEIALLL 183
Query: 155 PLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNI 214
+ L R+ L +L + L G ID+Y+ G E +N+
Sbjct: 184 MCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWPELEAFLFNVVEGK 243
Query: 215 GSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLS 274
S +G+ P+++YF L TL F+ +K ++ L+ + V S
Sbjct: 244 SSDWGTSPFYYYFVRLPWLFLNPTTLLFLLISFVYIK------PARLLIYVPLFFIFVYS 297
Query: 275 AVEHKEFRFVSPLLP-----------LCLYVITDALSRWSIRASSTMLWTTALVILVGNV 323
+ HKE+RF+ +P LC + I M ++ + +G+
Sbjct: 298 FLGHKEWRFIIYSIPWFNAASAIGASLCFNASKFGKKIFEILRL--MFFSGIIFGFIGSS 355
Query: 324 MPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILF-LMPC 367
Y+ G + + R Y E Q ++ + PC
Sbjct: 356 FL-LYVFQYAYPGGLA-------LTRLYEIENHPQVSVHMDVYPC 392
>pir||T28996 hypothetical protein ZC513.5 - Caenorhabditis elegans
Length = 369
Score = 247 bits (626), Expect = 3e-64
Identities = 73/378 (19%), Positives = 136/378 (35%), Gaps = 51/378 (13%)
Query: 43 GYGYLTWEWVQGIRSYVYPLLIAGLYK-------------------ILALLQLDS--AHL 81
Y + + V R+++ P+ +A L I A L L + A L
Sbjct: 4 KYDHSQFPGVVP-RTFIGPISLAILSSPMSFIFRFWAIPKMWQLLLIRATLGLMNAMAFL 62
Query: 82 LVVLPRIRKWA------LFLILV-PWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTA 134
RK+ L LI+ + + + SR L NT L I + G +
Sbjct: 63 YFARSVNRKFGRETAMYLRLIMCTQFHYIFYMSRPLPNTFALILVMI-VFERLLEGRYES 121
Query: 135 YLWPAAICCFLRPTAAVIWLPLSLY---HLRRSRQNVLELILKRFVLIGLLVAGLGIAID 191
+ A L V+ R + + + V I + + I ID
Sbjct: 122 AVRYATASVILFRCELVLLYGPIFLGYMISGRLKVFGFDGAIAIGVRIAAMCLAVSIPID 181
Query: 192 TYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVK 251
+Y+ G+ + E + +N+ N YG+ P+ WYF LP L TL G++ +
Sbjct: 182 SYFWGRPLWPEGEVMFFNVVENRSHEYGTQPFLWYFYSALPRCLLTTTLLVPLGLLVDRR 241
Query: 252 KSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASST-- 309
Q+++ + + + S + HKE RF+ +LP+ +R I +
Sbjct: 242 L-------PQIVLPSVIFIFLYSFLPHKELRFIIYVLPIFCLSAAVFCARMLINRHKSFF 294
Query: 310 --MLWTTALVILVGNV---MPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFL 364
+L+ ++ L+ NV +++ + G + + L+ + R + + +
Sbjct: 295 RMILFFGVILHLLANVLCTGMFLLVASKNYPG-FDALNYLQ---FQNRFDAKKPVTVYID 350
Query: 365 MPCHSTPYYSHIHQNVTM 382
C T +H N
Sbjct: 351 NACAQTGVNRFLHINDAW 368
>sp|Q09837|YADC_SCHPO HYPOTHETICAL 62.2 KD PROTEIN C4G8.12C IN CHROMOSOME I
pir||S62489 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
pir||T38857 hypothetical protein SPAC4G8.12c - fission yeast
(Schizosaccharomyces pombe)
emb|CAA91213.1| (Z56276) hypothetical protein [Schizosaccharomyces pombe]
Length = 533
Score = 241 bits (610), Expect = 2e-62
Identities = 78/425 (18%), Positives = 147/425 (34%), Gaps = 77/425 (18%)
Query: 3 LIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGY-LTWEW--VQGIRSYV 59
+IY FLLIL + +Y PDE+ QS ++ FG+ L WE+ + IRS V
Sbjct: 9 IIYTFLLILRFWFSQG---SSYIHPDEHLQSFQIFANKLFGWKVELPWEFTTKKPIRSVV 65
Query: 60 YPLLIAGLYKILALLQLDS-----AHLLVV------------------LPRIRKW-ALFL 95
++ +L S LL +P +W AL L
Sbjct: 66 PLNVMLLPIFLLCRCICKSNCSPYPILLFTRLYMCLISLLIDLSIWNIVPLNARWSALLL 125
Query: 96 ILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGE-------STAYLWPAAICCFLR-- 146
+ + T N++E + + + S Y + AI L
Sbjct: 126 YSSSFMATTFQTHTFTNSIETIFFFLTILFLSKLNSVPLNKKISYLYTFLLAIVSVLGFF 185
Query: 147 ------PTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGL--GIAIDTYWHGQL 198
++ S+ +++ N ++ L + + + A + I D ++G
Sbjct: 186 TRITFLAFVIAPYIYFSVRCFKKNVNNPKDIFLHLCIFVSVSFATVLACILEDYKFYGVF 245
Query: 199 IVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPV 258
++T + LKYN S +G H +F +P + G + + P
Sbjct: 246 VITFWNNLKYNSQIENLSQHGLHSRLTHFFTNMPLLCGP-------LIFVPKLWDVRKPA 298
Query: 259 SKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVI 318
+ L+ +F +LS H+E RF+ P + + + + W L +
Sbjct: 299 TWLWLLPVF----ILSLFPHQEPRFLLPAASIFIVNSGCLVRSY---------WIKFLFV 345
Query: 319 LVGNVMPAWYLSTVHQKGPIELMPKLREIARE---------YRDEREHQANILFLMPCHS 369
+ V+ A + +HQ G I + +++ I + ++ +S
Sbjct: 346 MYA-VVLAVFFGIMHQNGVIPAVLEVKNIIEQRNVTTMENCNLYFNPEMPTTIYFWKIYS 404
Query: 370 TPYYS 374
P +
Sbjct: 405 APTWM 409
>emb|CAA41123.1| (X58121) SMP3 protein [Saccharomyces cerevisiae]
Length = 516
Score = 240 bits (609), Expect = 3e-62
Identities = 92/428 (21%), Positives = 161/428 (37%), Gaps = 69/428 (16%)
Query: 5 YVFLLILAVRLASVFVVQTYY-VPDEYWQSLEV-AHKLTFGYGYLTWEW--VQGIRSYVY 60
Y + L L + + + Y PDE++Q +E+ A + G + WE+ RSY
Sbjct: 4 YQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
Query: 61 PLLIAGLYK---------------ILALLQLDSAHLL-----VVLPRI----RKWALF-- 94
LL+ G IL ++L + + ++P++ RK F
Sbjct: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFIK 123
Query: 95 --LILVPWFWFYTGSRTLANTLEASLTTIALSYFP--------WYGESTAYLWPAAICCF 144
L+L + + + T +N++E L+ + I F
Sbjct: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNGKNIQRRNFKNSVILGLIFSF 183
Query: 145 L----RPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQ-LI 199
A I+LP + + R + L + I + Y +G+ +
Sbjct: 184 GVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFV 243
Query: 200 VTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVS 259
+TP LKYN+ +G HP + + V LP +LG L IF Y +
Sbjct: 244 ITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQILGPVLLLAIF---------SGYKLD 294
Query: 260 KQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTAL--V 317
K I L+ LS +H+E RF+ PL+PL + + SST++
Sbjct: 295 KLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNW------TPLSSTLVNKKIFKGT 348
Query: 318 ILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIH 377
L+ N++ A+ + HQ G I+ + +Y R Q + +S P + ++
Sbjct: 349 WLLFNIIMAFIMGISHQAGIIQFLG-------DYFHFRTEQMGVHIWWKTYSPPTWMYMS 401
Query: 378 QNVTMRFL 385
N+T+ L
Sbjct: 402 NNLTVSSL 409
>ref|NP_014792.1| (NC_001147) Involved in glycosyl phosphatidyl inositol synthesis;
most likely an alpha 1,2 mannosyltransferase utilized
for addition of the fourth, side-branching mannose onto
the GPI core structure.; Smp3p [Saccharomyces
cerevisiae]
sp|Q04174|SMP3_YEAST SMP3 PROTEIN
pir||S67037 SMP3 protein - yeast (Saccharomyces cerevisiae)
gb|AAC49635.1| (U55020) Smp3p [Saccharomyces cerevisiae]
emb|CAA99355.1| (Z75057) ORF YOR149c [Saccharomyces cerevisiae]
Length = 516
Score = 238 bits (603), Expect = 2e-61
Identities = 91/428 (21%), Positives = 161/428 (37%), Gaps = 69/428 (16%)
Query: 5 YVFLLILAVRLASVFVVQTYY-VPDEYWQSLEV-AHKLTFGYGYLTWEW--VQGIRSYVY 60
Y + L L + + + Y PDE++Q +E+ A + G + WE+ RSY
Sbjct: 4 YQWWLYLVYAIGLMLCLGPSYIHPDEHFQCIEILAMQFMKVKGTIPWEFKSKFAARSYGP 63
Query: 61 PLLIAGLYK---------------ILALLQLDSAHLL-----VVLPRI----RKWALF-- 94
LL+ G IL ++L + + ++P++ RK F
Sbjct: 64 LLLVYGPLFTILESFPEIQDNPALILYSMRLQNYVMYLLCYHFLIPKLIRDERKAVQFMQ 123
Query: 95 --LILVPWFWFYTGSRTLANTLEASLTTIALSYFP--------WYGESTAYLWPAAICCF 144
L+L + + + T +N++E L+ + I F
Sbjct: 124 KSLLLTSYVTWTYQTHTFSNSIETLALISTLTVMEDMVNEKNIQRSNFKNSVILGLIFSF 183
Query: 145 L----RPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQ-LI 199
A I+LP + + R + L + I + Y +G+ +
Sbjct: 184 GVFNRVTFPAFIFLPCLILFWKFYRVHWKSFSLLLLSFSFSSCLFVLIDTNIYNNGKGFV 243
Query: 200 VTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVS 259
+TP LKYN+ +G HP + + V LP ++G L IF Y +
Sbjct: 244 ITPLNNLKYNLNVQNLQVHGLHPRYTHLLVNLPQIVGPVLLLAIF---------SGYKLD 294
Query: 260 KQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTAL--V 317
K I L+ LS +H+E RF+ PL+PL + + SST++
Sbjct: 295 KLSTYAIISGLLFLSFFQHQELRFLVPLVPLLVTNLNW------TPLSSTLVNKKIFKGT 348
Query: 318 ILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTPYYSHIH 377
L+ N++ A+ + HQ G I+ + +Y R Q + +S P + ++
Sbjct: 349 WLLFNIIMAFIMGISHQAGIIQFLG-------DYFHFRTEQMGVHIWWKTYSPPTWMYMS 401
Query: 378 QNVTMRFL 385
N+T+ L
Sbjct: 402 NNLTVSSL 409
>ref|NP_014427.1| (NC_001146) ExtraCellular Mutant; Ecm39p [Saccharomyces cerevisiae]
sp|P53730|YN8I_YEAST Hypothetical 62.7 kDa protein in SEC12-SSK2 intergenic region
pir||S63361 probable membrane protein YNR030w - yeast (Saccharomyces
cerevisiae)
emb|CAA96310.1| (Z71645) ORF YNR030w [Saccharomyces cerevisiae]
Length = 551
Score = 230 bits (583), Expect = 4e-59
Identities = 65/406 (16%), Positives = 141/406 (34%), Gaps = 81/406 (19%)
Query: 5 YVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLT-------FGYGYLTWEWVQGIRS 57
+ L + + + S ++Q + E +++ H + Y +L + V R+
Sbjct: 3 WSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVP-RT 61
Query: 58 YVYPLLIAGLYK----------------------ILALLQLDSAHLLVVLPRIRK----- 90
+V ++IA L + + ++ L + + L +
Sbjct: 62 FVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDMFDE 121
Query: 91 ----------------------WALFLILVPWFWFYTGSRTLAN-TLEASLTTIALSYFP 127
W L ++ + + +RTL N + LT +AL +
Sbjct: 122 ITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVAL-GWV 180
Query: 128 WYGESTAYLWPAAICCFLRPTAA-VIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGL 186
G A ++ +A+ + + ++L+ ++ L + G+ GL
Sbjct: 181 LLGRYNAAIFLSALVAIVFRLEVSALSAGIALFS-----VIFKKISLFDAIKFGIFGLGL 235
Query: 187 ----GIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPF 242
I +D+Y+ + + + +N+ S +G P YF+ L + P
Sbjct: 236 GSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPVTAYFTHYLRMM---FMPPT 292
Query: 243 IFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSR- 301
+ + K + L ++F ++VLS HKE+RF+ +P + + +
Sbjct: 293 VLLLNYFGYKLAPAKLKIVSLASLF-HIIVLSFQPHKEWRFIIYAVPSIMLLGATGAAHL 351
Query: 302 WSIRASSTMLWTTALVILVGNVMPA-------WYLSTVHQKGPIEL 340
W + L IL ++M + Y+S ++ G L
Sbjct: 352 WENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGEAL 397
>ref|NP_173134.1| (NM_101551) Ser/Thr protein kinase, putative [Arabidopsis thaliana]
Length = 919
Score = 228 bits (576), Expect = 3e-58
Identities = 60/321 (18%), Positives = 114/321 (34%), Gaps = 39/321 (12%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLLI 64
F+ + +R S + DE + E H + + G+ TWE+ +RSY+Y L
Sbjct: 399 FIALCYLRYMSA-TSNIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFH 457
Query: 65 A----------------GLYKILALLQLDSAHLLV---------VLPRIRKWALF-LILV 98
Y + L L SA RI +A+ L L
Sbjct: 458 ELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLT 517
Query: 99 PWFWFYTGSRTLANTLEASLTTI--ALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPL 156
F+ + L ++ ++ L F Y + A P + + +LP+
Sbjct: 518 SGC-FFASTSFLPSSFSMYAISLSSGLLLFEKYAMAVAVSVV--GVILGWPFSILAFLPV 574
Query: 157 SLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNI-G 215
+Y L + + + + + G+ + +D Y++ + + L YN+
Sbjct: 575 VIYSLVKR----FKQAFIAGAVTTIFLLGVSLLVDYYYYKRWTSSVLNLLIYNVLGGGES 630
Query: 216 SFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSA 275
YG+ +Y G L +F + V + + ++ +++ L +S
Sbjct: 631 HLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIWLAFMSL 690
Query: 276 VEHKEFRFVSPLLPLCLYVIT 296
HKE RF+ P+ PL +
Sbjct: 691 QPHKEERFLYPIYPLICVSAS 711
>ref|NP_496282.1| (NM_063881) C14A4.3.p [Caenorhabditis elegans]
sp|P54002|YTH3_CAEEL Hypothetical 75.5 kDa protein C14A4.3 in chromosome II
pir||T19245 hypothetical protein C14A4.3 - Caenorhabditis elegans
emb|CAA90107.1| (Z49909) weak similarity with a B. Flavum translocation protein
(Swiss Prot accession number P38376)~cDNA EST yk549e12.3
comes from this gene~cDNA EST yk618d6.3 comes from this
gene~cDNA EST yk549e12.5 comes from this gene~cDNA EST
yk618d6.5 comes from>
Length = 653
Score = 225 bits (570), Expect = 1e-57
Identities = 81/371 (21%), Positives = 140/371 (36%), Gaps = 51/371 (13%)
Query: 2 KLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEW--VQGIRSYV 59
VF ++L++R++ DE + E H +G G+ TWE+ V IRSY
Sbjct: 52 SFGSVFKMLLSIRISGAIW-GIINDCDEVYNYWEPLHLFLYGEGFQTWEYSPVYAIRSYF 110
Query: 60 YPLLIAGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWF---------------- 103
Y L + A L D+ ++ L R+ LF +L ++ F
Sbjct: 111 YIYLHYIPASLFANLFGDTKIVVFTLIRL-TIGLFCLLGEYYAFDAICKKINIATGRFFI 169
Query: 104 ----YTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICC------FLRPTAAVIW 153
++ LA+T + F G W A I C P +AV+
Sbjct: 170 LFSIFSSGMFLASTAFVPSSFCMAITFYILGAYLNENWTAGIFCVAFSTMVGWPFSAVLG 229
Query: 154 LPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNN 213
LP+ L + + + ++IGL + G+ + D+++ G+ ++ P YN+ +
Sbjct: 230 LPIVADMLLL--KGLRIRFILTSLVIGLCIGGVQVITDSHYFGKTVLAPLNIFLYNVVSG 287
Query: 214 IG-SFYGSHPWHWYFSV--------------GLPTVLGINTLPFIFGVMETVKKSEKYPV 258
G S YG P +Y G P L T ++ V +++
Sbjct: 288 PGPSLYGEEPLSFYIKNLFNNWNIVIFAAPFGFPLSLAYFTKVWMS-QDRNVALYQRFAP 346
Query: 259 SKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALS---RWSIRASSTMLWTTA 315
L +T L++ + HKE RF+ P+ P + AL R ++ +
Sbjct: 347 IILLAVTTAAWLLIFGSQAHKEERFLFPIYPFIAFFAALALDATNRLCLKKLGMDNILSI 406
Query: 316 LVILVGNVMPA 326
L IL ++ A
Sbjct: 407 LFILCFAILSA 417
>gb|AAF99843.1|AC051629_10 (AC051629) Hypothetical protein [Arabidopsis thaliana]
Length = 570
Score = 216 bits (545), Expect = 9e-55
Identities = 60/321 (18%), Positives = 114/321 (34%), Gaps = 39/321 (12%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLLI 64
F+ + +R S + DE + E H + + G+ TWE+ +RSY+Y L
Sbjct: 50 FIALCYLRYMSA-TSNIIHDCDEVFNYWEPLHYILYKSGFQTWEYSSNFALRSYLYILFH 108
Query: 65 A----------------GLYKILALLQLDSAHLLV---------VLPRIRKWALF-LILV 98
Y + L L SA RI +A+ L L
Sbjct: 109 ELAGRPASWWFGDDKVRVFYAVRLFLGLVSAVSDTVLVVALSRKYGKRIATYAVAMLCLT 168
Query: 99 PWFWFYTGSRTLANTLEASLTTI--ALSYFPWYGESTAYLWPAAICCFLRPTAAVIWLPL 156
F+ + L ++ ++ L F Y + A P + + +LP+
Sbjct: 169 SGC-FFASTSFLPSSFSMYAISLSSGLLLFEKYAMAVAVSVV--GVILGWPFSILAFLPV 225
Query: 157 SLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNI-G 215
+Y L + + + + + G+ + +D Y++ + + L YN+
Sbjct: 226 VIYSLVKR----FKQAFIAGAVTTIFLLGVSLLVDYYYYKRWTSSVLNLLIYNVLGGGES 281
Query: 216 SFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSA 275
YG+ +Y G L +F + V + + ++ +++ L +S
Sbjct: 282 HLYGTEGALFYIRNGFNNFNFCFILAMLFVAIYPVIRRKYDRALLVVISPMYIWLAFMSL 341
Query: 276 VEHKEFRFVSPLLPLCLYVIT 296
HKE RF+ P+ PL +
Sbjct: 342 QPHKEERFLYPIYPLICVSAS 362
>emb|CAA42931.1| (X60381) ORF2 [Saccharomyces cerevisiae]
Length = 278
Score = 215 bits (544), Expect = 1e-54
Identities = 74/275 (26%), Positives = 121/275 (43%), Gaps = 45/275 (16%)
Query: 230 GLPTVLGINTLPFIFGVMETVKKSEK----YPVSKQLLITIFLTLVVLSAVEHKEFRFVS 285
LP VLG + F FG+ + K Q+ +TI L L+V S + HKEFRF+
Sbjct: 1 ALPIVLGASIPAFAFGLFFPLSKRSFPKKYLNPFFQVKLTILLNLLVYSTLPHKEFRFIF 60
Query: 286 PLLPLCLYVITDALSRW--SIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMPK 343
PL PL + + + L R + L + ++ +V A L T H+ G IE+M
Sbjct: 61 PLQPLFILISSFGLLRLDRDYWKRLSGLKSLLWLVPFVSVFIALLLDTFHESGSIEVM-- 118
Query: 344 LREIAREYRDEREHQANILFLMPCHSTPYYSHIHQNVTMRF--LTCEPNLE--------- 392
++ E ++ F+MPCHSTP S++H++ +TC P L
Sbjct: 119 ------KFLHEEPEIDSLGFIMPCHSTPGQSYLHRSDIQDLWSITCNPPLHLLGDPEAYS 172
Query: 393 KKEQYKDEADRFFEDPVHWINSHIPMHPLT-----------ALPTHVVLFDPLAENI--- 438
K E Y DE+D ++D +I + P PT++V+F+ +
Sbjct: 173 KLETYMDESDHLYDDISAFIYKNFPPPFRKDLRSPGKTYSHEWPTYLVVFEHMENAFLKD 232
Query: 439 ----SVFLRNYRLLHRIEHAENRQSRTGRSILVYQ 469
S ++ R + + H ++R R+G I+ Y+
Sbjct: 233 FLKDSSYIEYNRFFNSLAHWDSR--RSGDIIIYYK 265
>ref|NP_014180.1| (NC_001146) catalyzes the transfer of mannose from Dol-P-Man to
lipid-linked oligosaccharides; Alg9p [Saccharomyces
cerevisiae]
sp|P53868|ALG9_YEAST Probable mannosyltransferase ALG9
pir||S63177 mannosyl transferase (EC 2.4.1.-) - yeast (Saccharomyces
cerevisiae)
emb|CAA96122.1| (Z71495) ORF YNL219c [Saccharomyces cerevisiae]
emb|CAA65277.1| (X96417) putative mannosyltransferase [Saccharomyces cerevisiae]
Length = 555
Score = 214 bits (540), Expect = 4e-54
Identities = 78/366 (21%), Positives = 126/366 (34%), Gaps = 55/366 (15%)
Query: 4 IYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYP 61
I + LL+ R+ DE + E + L G+G TWE+ IRS+ +
Sbjct: 8 ISLLLLLFLTRVYIQPTFSLISDCDETFNYWEPLNLLVRGFGKQTWEYSPEYSIRSWAFL 67
Query: 62 LLIA-GLYKI---------------LALLQLDSAHLLVVLPRIRKWALFLILVPWF---- 101
L LY + A L S + L R +L L + +
Sbjct: 68 LPFYCILYPVNKFTDLESHWNFFITRACLGFFSFIMEFKLHREIAGSLALQIANIWIIFQ 127
Query: 102 -----WFYTGSRTLANTLEASLTTIALSYFPWY---------GESTAYLWPAAICCFLRP 147
WF+ L + + L A + Y +S AY + A P
Sbjct: 128 LFNPGWFHASVELLPSAVAMLLYVGATRHSLRYLSTGSTSNFTKSLAYNFLA--SILGWP 185
Query: 148 TAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLK 207
++ LPL L++L R LI L A I D+ ++G+L + L
Sbjct: 186 FVLILSLPLCLHYLFNHRIISTIRTAFDCCLIFSLTAFAVIVTDSIFYGKLAPVSWNILF 245
Query: 208 YNIFN----NIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLL 263
YN+ N + + +G PW++Y L + I G+ L
Sbjct: 246 YNVINASEESGPNIFGVEPWYYYPLNLLLNFPLPVLVLAILGIFHLRLW--------PLW 297
Query: 264 ITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDAL---SRWSIRA--SSTMLWTTALVI 318
++F + V + HKE RF+ P+ L + A R + + L+I
Sbjct: 298 ASLFTWIAVFTQQPHKEERFLYPIYGLITLSASIAFYKVLNLFNRKPILKKGIKLSVLLI 357
Query: 319 LVGNVM 324
+ G M
Sbjct: 358 VAGQAM 363
>ref|NP_079439.1| (NM_025163) hypothetical protein FLJ12768 [Homo sapiens]
dbj|BAB14263.1| (AK022830) unnamed protein product [Homo sapiens]
Length = 579
Score = 210 bits (532), Expect = 4e-53
Identities = 85/449 (18%), Positives = 151/449 (32%), Gaps = 91/449 (20%)
Query: 1 MKLIYVFLLILAVRLASVFVVQTYY-VPDEYWQSLEV-AHKLTFGYGYLTWEW--VQGIR 56
+++++ L +L R+ + QT Y PDE++QS EV A + WE+ R
Sbjct: 34 VRVLWGGLSLL--RVLWCLLPQTGYVHPDEFFQSPEVMAEDILGVQAARPWEFYPSSSCR 91
Query: 57 SYVYPLLIAGLYK--------ILALLQLDSAHLLVVLPRIRK------------------ 90
S ++PLLI+G + L S + L+V PR+
Sbjct: 92 SVLFPLLISGSTFWLLRLWEELGPWPGLVSGYALLVGPRLLLTALSFALDGAVYHLAPPM 151
Query: 91 -----WALFLILVPWFWFYTGSRTLANTLEASLTTIALSYF----------------PWY 129
AL L+ + +RT +NT+E L T L P +
Sbjct: 152 GADRWNALALLSGSYVTLVFYTRTFSNTIEGLLFTWLLVLVSSHVTWGPTRKEPAPGPRW 211
Query: 130 GESTAYLWPAAICCFLRPTAAVIWLPLSLYH----LRRSRQNVLELILKRFVLIGLLVAG 185
AA F RPT + L + L A
Sbjct: 212 RSWLLGGIVAAGF-FNRPTFLAFAVVPLYLWGTRGATNPGLKSLTREALVLLPGATLTAA 270
Query: 186 LGIAIDTYWH------GQLIVTPYEFLKYNIFNNIGSFYGSHPWHWYF-SVGLPTVLGIN 238
+ +A D+++ L++TP FL YN+ + +G+H + G ++
Sbjct: 271 VFVATDSWYFSSPATSRNLVLTPVNFLHYNLNPQNLARHGTHARLTHLAVNGFLLFGVLH 330
Query: 239 T---------------LPFIFGVMETVKKSEKYPVSKQLLITI-FLTLVVLSAVEHKEFR 282
G++ + + L+ + F+ L +LSA H+E R
Sbjct: 331 AQALQAAWQQLQVGLQASAQMGLLRALGARSLLSSPRSYLLLLYFMPLALLSAFSHQEAR 390
Query: 283 FVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWYLSTVHQKGPIELMP 342
F+ PLL + + + + + W +++ N + A +HQ G + +
Sbjct: 391 FLIPLLVPLVLLCS--------PQTQPVPWKG--TVVLFNALGALLFGCLHQGGLVPGLE 440
Query: 343 KLREIAREYRDEREHQANILFLMPCHSTP 371
L ++ L + P
Sbjct: 441 YLEQVVHAPVLPSTPTHYTLLFTHTYMPP 469
>gb|AAD53921.1|AF179611_5 (AF179611) phosphatidylinositol glycan homolog [Zymomonas mobilis]
Length = 509
Score = 177 bits (445), Expect = 6e-43
Identities = 75/427 (17%), Positives = 143/427 (32%), Gaps = 67/427 (15%)
Query: 1 MKLIYVFLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVY 60
+ ++ + LL L +R+ ++F + YY PDE +Q LE AH+L FGY + WE+ G+R +
Sbjct: 21 LTVLLITLLALCLRMTAIFPIG-YYHPDEIFQYLEQAHRLAFGYSVIPWEYRYGMRGGLV 79
Query: 61 PLLIAGLYKILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYTGSR---TLANTLEAS 117
P+L+A K+ ++ S L VLP L L + Y R L
Sbjct: 80 PVLLAAAMKMGDIMNTQS-FLYWVLPH--AITALLSLGVIWSAYKLGRLHSFFTGCLAMF 136
Query: 118 LTT----IALSYFPWYGESTAY--LWPAA--ICCFLRPTAAVIWLPLSLYHLRRSRQNVL 169
+ I L ES ++ PAA + + +++I + R
Sbjct: 137 VAATWYEIVLFAAHPLSESLSFAAFMPAAYYLIAEEKKKSSLILSGFLMGLSALLR---- 192
Query: 170 ELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYEFLKYNIFNNIGSFY-GSHPWHWYFS 228
+++ L + + I+ G I+ + +++ + G +P W F
Sbjct: 193 ----FQYIPSILFITLFTLRINVRQWGYFILGGLGAV---FISSLSDIFIGEYPLLWLFK 245
Query: 229 V-----GLPTVLGINTLPFIFGVMETVKKSEKYPVSKQ------------LLITIFLTLV 271
T P + + + + L T + L+
Sbjct: 246 NIQQNLIFHRAEDYGTAPIYSYFFDIWTNWKWFSLILPIPILVAAYRYPALFGTALVNLI 305
Query: 272 VLSAVEHKEFRFVSPLLPLCLYVITDALSRW-------SIRASSTMLWTTALVILVGNVM 324
V HKE+RF+ + + + + + A
Sbjct: 306 FHMLVSHKEYRFIFLSSGIFIILAAIGSALLIEKATINFTPLHKKLAQIAAFTAWGACSF 365
Query: 325 PAWYLSTVH---QKGPIELMPK---LREIAREYRDEREHQANILFLMPCHSTPYYSHIHQ 378
+ H +G ++ K L + + I + + YS +H+
Sbjct: 366 LCSTGNISHWYQYRGVLQAEMKARSLSNLCGLTLYQ------IDYW----ESGGYSLLHR 415
Query: 379 NVTMRFL 385
+ + L
Sbjct: 416 PIPIYSL 422
>ref|XP_016392.3| (XM_016392) hypothetical protein FLJ12768 [Homo sapiens]
Length = 457
Score = 171 bits (430), Expect = 3e-41
Identities = 63/359 (17%), Positives = 110/359 (30%), Gaps = 69/359 (19%)
Query: 70 ILALLQLDS----AHLLVVLPRIRKW----------ALFLILVPWFWFYTGSRTLANTLE 115
+ LDS LL P W AL L+ + +RT +NT+E
Sbjct: 1 MRCWWGLDSSSLPFPLLWTGP-CTTWPPAMGADRWNALALLSGSYVTLVFYTRTFSNTIE 59
Query: 116 ASLTTIALSYF----------------PWYGESTAYLWPAAICCFLRPTAAVIWLPLSLY 159
L T L P + AA F RPT +
Sbjct: 60 GLLFTWLLVLVSSHVTWGPTRKEPAPGPRWRSWLLGGIVAAGF-FNRPTFLAFAVVPLYL 118
Query: 160 H----LRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWH------GQLIVTPYEFLKYN 209
L + L A + +A D+++ L++TP FL YN
Sbjct: 119 WGTRGATNPGLKSLTREALVLLPGATLTAAVFVATDSWYFSSPATSRNLVLTPVNFLHYN 178
Query: 210 IFNNIGSFYGSHPWHWYF-SVGLPTVLGINTLPFIF---------------GVMETVKKS 253
+ + +G+H + G ++ G++ +
Sbjct: 179 LNPQNLARHGTHARLTHLAVNGFLLFGVLHAQALQAAWQRLQVGLQASAQMGLLRALGAR 238
Query: 254 EKYPVSKQLLITI-FLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLW 312
+ L+ + F+ L +LSA H+E RF+ PLL + + + + + W
Sbjct: 239 SLLSSPRSYLLLLYFMPLALLSAFSHQEARFLIPLLVPLVLLCS--------PQTQPVPW 290
Query: 313 TTALVILVGNVMPAWYLSTVHQKGPIELMPKLREIAREYRDEREHQANILFLMPCHSTP 371
+ + N + A +HQ G + + L ++ L + P
Sbjct: 291 KG--TVALFNALGALLFGCLHQGGLVPGLEYLEQVVHAPVLPSTPTHYTLLFTHTYMPP 347
>pir||T16945 hypothetical protein T27F7.3 - Caenorhabditis elegans
Length = 283
Score = 149 bits (373), Expect = 2e-34
Identities = 44/165 (26%), Positives = 73/165 (43%), Gaps = 19/165 (11%)
Query: 206 LKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLIT 265
+ +N+ + +G HPW+WY G+P VL + +P I G++ + + L+
Sbjct: 129 IAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGP-------NIFRPSLLP 181
Query: 266 IFLT---LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGN 322
F T ++V S + HKE RF+ P++PL A S M A+ N
Sbjct: 182 FFATITYIIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRGSAMAVMIAI-----N 236
Query: 323 VMPAWYLSTVHQK----GPIELMPKLREIAREYRDEREHQANILF 363
+ A + S HQK G I P+ E+ + D+R+ + L
Sbjct: 237 IGIALFTSRYHQKHSCNGTIVEHPEYGEVIQLTGDQRDKVKDFLI 281
Score = 79.3 bits (194), Expect = 2e-13
Identities = 27/57 (47%), Positives = 41/57 (71%)
Query: 10 ILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAG 66
++ R SV++V +++VPDE +QS EVAH L +G G+L+WEW +RS+ +P LIA
Sbjct: 75 LVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPALIAF 131
>dbj|BAA87150.1| (AB027846) Hypothetical protein [Schizosaccharomyces pombe]
Length = 197
Score = 149 bits (373), Expect = 2e-34
Identities = 39/204 (19%), Positives = 70/204 (34%), Gaps = 7/204 (3%)
Query: 85 LPRIRKWALFLILVPWFWFYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCF 144
+ + Y SR L+N T +LS +
Sbjct: 1 GTLSGALFILFSCAQFHLVYYMSRPLSNIFGLIATNHSLSL-LLKNNYYGSISILVFAAA 59
Query: 145 LRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIAIDTYWHGQLIVTPYE 204
+ + + L + L R+ L +L + L G ID+Y+ G E
Sbjct: 60 IVRSEIALLLMCLILPLLLQRRITLSKLLLVGISSSLAAVGASFLIDSYFWGAWCWPELE 119
Query: 205 FLKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLI 264
+N+ S +G+ P+++YF L TL F+ +K ++ L+
Sbjct: 120 AFLFNVVEGKSSDWGTSPFYYYFVRLPWLFLNPTTLLFLLISFVYIK------PARLLIY 173
Query: 265 TIFLTLVVLSAVEHKEFRFVSPLL 288
+ V S + HKE+RF+ +
Sbjct: 174 VPLFFIFVYSFLGHKEWRFIIYSI 197
>gb|AAH21379.1|AAH21379 (BC021379) Similar to hypothetical protein MGC3136 [Mus musculus]
Length = 385
Score = 147 bits (369), Expect = 4e-34
Identities = 42/212 (19%), Positives = 82/212 (37%), Gaps = 36/212 (16%)
Query: 8 LLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTF------GYGYLTWEWVQGIRSYVYP 61
LL L V +A++ +V Y E +L+ H L + Y + + V R+++ P
Sbjct: 14 LLGLLVTVATIHLVICPYTKVEESFNLQATHDLLYHQLDIDKYDHHEFPGVVP-RTFLGP 72
Query: 62 LLIAGLYK----ILALLQLDSAH----------------LLVVLPRIRKWALFLILVPWF 101
L+IA +L+LL++ + L + +R+ + V +
Sbjct: 73 LVIAAFSSPVVYVLSLLEVSKFYSQLIVRGVLGLGVISGLWTLQKEVRQQFGATVAVMFC 132
Query: 102 W--------FYTGSRTLANTLEASLTTIALSYFPWYGESTAYLWPAAICCFLRPTAAVIW 153
W + +RTL N L ++ AL+ + ++W +A +
Sbjct: 133 WISATQFHLMFYCTRTLPNVLALAVVLPALTAW-LQRRWALFVWLSAFVIIGFRAELAML 191
Query: 154 LPLSLYHLRRSRQNVLELILKRFVLIGLLVAG 185
L ++L R+ + +L+ + GLL G
Sbjct: 192 LGIALLLTLYQRRLTVARVLRHAIPAGLLCLG 223
Score = 47.7 bits (113), Expect = 5e-04
Identities = 28/181 (15%), Positives = 50/181 (27%), Gaps = 32/181 (17%)
Query: 225 WYFSVGLP--TVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKE-- 280
+Y + LP L + + ++I L +L +
Sbjct: 143 FYCTRTLPNVLALAVVLPALTAWLQRRWALFVWLSAF--VIIGFRAELAMLLGIALLLTL 200
Query: 281 ----------FRFVSPLLPLCL-----YVITDALSRWSIRASSTMLWTTALVILVGNVMP 325
R P LCL V W ML T +++ V
Sbjct: 201 YQRRLTVARVLRHAIPAGLLCLGKLASLVCLLNKKSWPY-KVRAMLVTGHILVNVAYTAT 259
Query: 326 AWYLSTVHQKGPIELMPKLREIAREYRDEREHQANI--LFLMPCHSTPYYSHIHQNVTMR 383
+ Y+S + G + M +L E+ Q ++ + T + N R
Sbjct: 260 SLYVSHFNYPGGV-AMQQLHELV-------PPQTDVLLHIDVAAAQTGVSRFLQVNDDWR 311
Query: 384 F 384
+
Sbjct: 312 Y 312
>ref|NP_494918.1| (NM_062517) T27F7.3a.p [Caenorhabditis elegans]
gb|AAK39304.1| (U58762) weakly similar to protein translation factor SUI1 family
[Caenorhabditis elegans]
Length = 232
Score = 142 bits (355), Expect = 2e-32
Identities = 44/165 (26%), Positives = 73/165 (43%), Gaps = 19/165 (11%)
Query: 206 LKYNIFNNIGSFYGSHPWHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLIT 265
+ +N+ + +G HPW+WY G+P VL + +P I G++ + + L+
Sbjct: 65 IAFNVVQGGSALFGVHPWYWYIVSGIPAVLTVQMIPIIVGLLGP-------NIFRPSLLP 117
Query: 266 IFLT---LVVLSAVEHKEFRFVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGN 322
F T ++V S + HKE RF+ P++PL A S M A+ N
Sbjct: 118 FFATITYIIVHSLLPHKEQRFLLPIIPLLCIYAGGAFQNLKKWRGSAMAVMIAI-----N 172
Query: 323 VMPAWYLSTVHQK----GPIELMPKLREIAREYRDEREHQANILF 363
+ A + S HQK G I P+ E+ + D+R+ + L
Sbjct: 173 IGIALFTSRYHQKHSCNGTIVEHPEYGEVIQLTGDQRDKVKDFLI 217
Score = 76.2 bits (186), Expect = 1e-12
Identities = 27/57 (47%), Positives = 41/57 (71%)
Query: 10 ILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWVQGIRSYVYPLLIAG 66
++ R SV++V +++VPDE +QS EVAH L +G G+L+WEW +RS+ +P LIA
Sbjct: 11 LVVFRCISVYLVASWFVPDEVYQSAEVAHHLVYGTGHLSWEWRHSLRSFFHPALIAF 67
>gb|AAF47201.1| (AE003464) CG3419 gene product [Drosophila melanogaster]
Length = 830
Score = 128 bits (320), Expect = 2e-28
Identities = 49/263 (18%), Positives = 83/263 (30%), Gaps = 50/263 (19%)
Query: 135 YLWPAAICCFLRPTAAVIWLPLSLYHLRR---SRQNVLELILKRFVLI---GLLVAGLGI 188
A F RPT + P+ + L R +R R L L L I
Sbjct: 229 STICVAGV-FNRPTFLLFGAPMVFFWLLRGMGTRSITFRDFNLRIALFCLCALPALVLFI 287
Query: 189 AIDTYWHGQ---------------LIVTPYEFLKYNIFNNIGSFYGSHPWHWYFSVGLP- 232
D+ ++ + TP+ F+K N+ + + +G HP + + V +P
Sbjct: 288 FCDSLYYQHLTLGELHMMHLSIDNFVFTPWNFIKANLDSAQTASHGVHPCYVHLMVNMPM 347
Query: 233 ----TVLGINTLPFIFGVMETVKKSEKYPVSK----QLLITIFLTLVVLSAVEHKEFRFV 284
L + + + P + + IF+ L LS + H+E RF+
Sbjct: 348 LFNVLALASLGAFAQLLLRFFRAEYQVLPRFQSIVSLMSGAIFVPLFFLSLINHQEPRFL 407
Query: 285 SPL-LPLCLY--------VITDA-------LSRWSIRASSTMLWTTALV---ILVGNVMP 325
P+ PL L L R + + + V NV
Sbjct: 408 LPVTFPLILLHAPKLITGFSAKYPFQKDHPLLRLFYDKLLSSKASGPYLLKIWYVSNVAL 467
Query: 326 AWYLSTVHQKGPIELMPKLREIA 348
+ +HQ G L + +
Sbjct: 468 TLFFGFIHQAGVYPLAADISHVI 490
Score = 36.4 bits (84), Expect = 1.2
Identities = 40/158 (25%), Positives = 62/158 (38%), Gaps = 38/158 (24%)
Query: 4 IYVFLLILAVRLASVFVVQTYY-VPDEYWQSLEVAHKLTFGYGY-LTWEW--VQGIRS-Y 58
+ + AVRL VFV Q Y PDE++QS+EV F + TWE+ +RS
Sbjct: 17 LSTYFCFAAVRLLLVFVPQLGYVHPDEFFQSVEVMTGDHFRLEHTRTWEFNNSLPVRSIV 76
Query: 59 VYPLLIAGLYK--------ILAL--LQLDSAHLLVVLPR-----------------IRKW 91
+ L+ + + A L+L + VV PR R +
Sbjct: 77 LPFALLRIPWSFYEFVAECLKAWWQLELLGTYAYVVFPRLIYTLISFSNDYCLFRICRLY 136
Query: 92 A------LFLILVPWFWFYTGSRTLANTLEASLTTIAL 123
L + W G+RT +N+LE ++ + L
Sbjct: 137 GLRFEIRLLAMGSSWILLVFGTRTFSNSLEMAMCSWLL 174
>dbj|BAB21931.1| (AB055306) hypothetical protein [Macaca fascicularis]
Length = 198
Score = 102 bits (253), Expect = 2e-20
Identities = 33/134 (24%), Positives = 47/134 (34%), Gaps = 31/134 (23%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWEWV--QGIRSYVYPLLI 64
F +L+ RL + + DE + E H L +G G+ TWE+ IRSY Y LL
Sbjct: 62 FKCLLSARLCAALLSNISD-CDETFNYWEPTHYLIYGEGFQTWEYSPAYAIRSYAYLLLH 120
Query: 65 AG----------------LYKILALLQLDSAH--LLVVLPRIRKWAL--------FLILV 98
A Y + LL S L +K+ L FL+L
Sbjct: 121 AWPAAFHARILQTNKILVFYFLRCLLAFVSCICELYFYKAVCKKFGLHVSRMMLAFLVLS 180
Query: 99 PWFWFYTGSRTLAN 112
+ S +
Sbjct: 181 TGM--FCSSSVYPS 192
>emb|CAC02000.2| (AL390114) possible hypothetical 66.3 Kd protein c1834.05 in
chromosome I precursor [Leishmania major]
Length = 822
Score = 83.6 bits (205), Expect = 8e-15
Identities = 25/162 (15%), Positives = 43/162 (26%), Gaps = 32/162 (19%)
Query: 7 FLLILAVRLASVFVVQTYYVPDEYWQSLEVAHKLTFGYGYLTWE--WVQGIRSYVYPLLI 64
FLL+ + + DE + +E H L +G G TWE +RS+++ +
Sbjct: 15 FLLLSLTHYFASSFLPISD-CDETFNFIEPIHYLLYGSGKQTWEVCSRFALRSWLFLWIH 73
Query: 65 AGLYK-ILALLQLDSAHLLVVLPRIRKWALFLILVPWFWFYT------------------ 105
A I L S + L L F+ +
Sbjct: 74 AWPVVLIRGAASLSSVRVYFYLR--MLNGCAAALAELFFVCSVWFTLSGKAAAVALLLLL 131
Query: 106 --------GSRTLANTLEASLTTIALSYFPWYGESTAYLWPA 139
L + + L + T+
Sbjct: 132 ANYPIQHAAVSVLPTSFAMMCNFVVLGSWLRTQSWTSSSALL 173
Score = 70.7 bits (172), Expect = 6e-11
Identities = 14/65 (21%), Positives = 21/65 (31%)
Query: 241 PFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFRFVSPLLPLCLYVITDALS 300
P V ++ F+ + ++ HKE RF+SP P L T L
Sbjct: 417 PLPAATTAAVGSRLSRERELLHIMPFFVWFLFWMSIAHKEERFMSPAYPFMLLAATRTLC 476
Query: 301 RWSIR 305
Sbjct: 477 LMFFP 481
Score = 51.3 bits (122), Expect = 4e-05
Identities = 20/108 (18%), Positives = 40/108 (36%), Gaps = 9/108 (8%)
Query: 130 GESTAYLWPAAICCFLRPTAAVIWLPLSLYHLRRSRQNVLELILKRFVLIGLLVAGLGIA 189
G + + A P AA+I + L L R L L ++ A + +A
Sbjct: 229 GAALCFSVLA--VVTGWPFAALISALVGLDLLLRFPVRTLACTLGSLLVA---CAAVFVA 283
Query: 190 IDTYWHGQLIVTPYEFLKYNIFNNIGS---FYGSHPWHWYFSVGLPTV 234
D ++ + ++ + + YN F G +G P +++ +
Sbjct: 284 -DVRYYCRWTLSSWNVVMYNGFGGSGRGPELFGVEPIFFFWKNLMLNF 330
>ref|NP_069450.1| (NC_000917) conserved hypothetical protein [Archaeoglobus fulgidus]
pir||H69326 conserved hypothetical protein AF0616 - Archaeoglobus fulgidus
gb|AAB90624.1| (AE001062) conserved hypothetical protein [Archaeoglobus fulgidus]
Length = 533
Score = 45.0 bits (106), Expect = 0.003
Identities = 24/106 (22%), Positives = 46/106 (42%), Gaps = 2/106 (1%)
Query: 223 WHWYFSVGLPTVLGINTLPFIFGVMETVKKSEKYPVSKQLLITIFLTLVVLSAVEHKEFR 282
W +Y + L V + + F + K + LL I L ++L+ + +K+ R
Sbjct: 292 WIYYANSILDAVGAVFLILFAVSIYYLYKN--NRYLFLGLLTPIALIYIILTLLSNKDPR 349
Query: 283 FVSPLLPLCLYVITDALSRWSIRASSTMLWTTALVILVGNVMPAWY 328
++ P+LP I +S + R ST+L L+ + N+ +
Sbjct: 350 YIMPVLPFVAISIGVFVSSLANRKYSTILTFIILLFGLLNISALTF 395
CPU time: 168.61 user secs. 2.84 sys. secs 171.45 total secs.
Database: nr
Posted date: Apr 21, 2002 2:19 PM
Number of letters in database: 277,845,442
Number of sequences in database: 887,402
Lambda K H
0.317 0.179 0.513
Gapped
Lambda K H
0.270 0.0629 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 387421791
Number of Sequences: 887402
Number of extensions: 22350998
Number of successful extensions: 96475
Number of sequences better than 10.0: 770
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 725
Number of HSP's that attempted gapping in prelim test: 95209
Number of HSP's gapped (non-prelim): 1420
length of query: 512
length of database: 277,845,442
effective HSP length: 51
effective length of query: 461
effective length of database: 232,587,940
effective search space: 107223040340
effective search space used: 107223040340
T: 11
A: 40
X1: 15 ( 6.9 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 40 (20.8 bits)
S2: 76 (33.6 bits)