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GPI Anchor Biosynthesis Report: T20374 (PIG-A family, Caenorhabditis elegans)




BLASTP 2.1.1 [Aug-8-2000]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (444 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................


Distribution of 55 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold
Score E Sequences producing significant alignments: (bits) Value ref|NP_495840.1| (NM_063439) phosphatidylinositol biosyntheti... 923 0.0 pir||A55731 GPI-anchor biosynthesis protein PIG-A - mouse >gi... 439 e-122 ref|NP_002632.1| (NM_002641) phosphatidylinositol glycan, cla... 432 e-120 ref|NP_566874.1| (NM_114379) n-acetylglucosaminyl-phosphatidy... 428 e-119 pir||T47450 n-acetylglucosaminyl-phosphatidylinositol-like pr... 415 e-115 pir||T40367 n-acetylglucosaminyl-phosphatidylinositol - fissi... 376 e-103 gb|AAF76891.1| (AF267484) PIG-A [Paramecium tetraurelia] 372 e-102 ref|NP_015150.2| (NC_001148) N-acetylglucosaminyl-phosphatidy... 365 e-100 pir||S65187 GPI-anchor biosynthesis protein PIG-A - yeast (Sa... 360 2e-98 gb|AAF57802.1| (AE003802) CG6401 gene product [Drosophila mel... 360 2e-98 prf||1804343A SPT14 gene [Saccharomyces cerevisiae] 358 1e-97 ref|XP_045453.1| (XM_045453) similar to phosphatidylinositol ... 227 3e-58 emb|CAB57276.1| (X77725) PIG-A [Homo sapiens] 176 6e-43 pir||I52665 class A GlcNAc-inositol phospholipid assembly pro... 126 5e-28 ref|NP_065205.1| (NM_020472) phosphatidylinositol glycan, cla... 119 9e-26 ref|NP_126928.1| (NC_000868) GALACTOSYLTRANSFERASE or LPS BIO... 111 2e-23 ref|NP_143674.1| (NC_000961) hypothetical protein [Pyrococcus... 107 4e-22 ref|NP_228553.1| (NC_000853) conserved hypothetical protein [... 99 7e-20 ref|NP_275316.1| (NC_000916) LPS biosynthesis RfbU related pr... 95 2e-18 gb|AAL81485.1| (AE010240) glycosyl transferase [Pyrococcus fu... 94 4e-18 ref|NP_266369.1| (NC_002662) LPS biosynthesis protein [Lactoc... 94 4e-18 ref|NP_148357.1| (NC_000854) N-acetylglucosaminyl-phosphatidy... 94 5e-18 ref|NP_437172.1| (NC_003078) putative membrane-anchored glyco... 86 8e-16 gb|AAL82009.1| (AE010283) glycosyl transferase [Pyrococcus fu... 86 1e-15 ref|NP_472029.1| (NC_003212) weakly similar to human N-acetyl... 85 2e-15 ref|NP_466078.1| (NC_003210) weakly similar to human N-acetyl... 83 8e-15 ref|NP_440248.1| (NC_000911) unknown protein [Synechocystis s... 81 4e-14 ref|NP_228431.1| (NC_000853) lipopolysaccharide biosynthesis ... 80 1e-13 gb|AAL80915.1| (AE010196) hypothetical protein [Pyrococcus fu... 78 3e-13 dbj|BAB18471.1| (AB033991) BtrM [Bacillus circulans] 77 4e-13 ref|NP_213400.1| (NC_000918) hypothetical protein [Aquifex ae... 77 5e-13 emb|CAB50741.1| (AJ243803) putative glycosyl transferase [Str... 77 6e-13 ref|NP_248617.1| (NC_000909) LPS biosynthesis protein, putati... 75 2e-12 ref|NP_242281.1| (NC_002570) BH1415~unknown conserved protein... 73 1e-11 ref|NP_378386.1| (NC_003106) 352aa long conserved hypothetica... 71 3e-11 ref|NP_489275.1| (NC_003272) probable glycosyl transferase [N... 71 3e-11 ref|NP_275513.1| (NC_000916) LPS biosynthesis RfbU related pr... 70 6e-11 ref|NP_248171.1| (NC_000909) conserved hypothetical protein [... 70 1e-10 ref|NP_489278.1| (NC_003272) glycosyltransferase [Nostoc sp. ... 69 1e-10 ref|NP_127136.1| (NC_000868) LPS BIOSYNTHESIS RFBU RELATED PR... 69 2e-10 emb|CAB43611.1| (AJ239004) galactosyl transferase [Streptococ... 69 2e-10 gb|AAK20702.1|AF316641_8 (AF316641) WciS [Streptococcus pneum... 69 2e-10 ref|NP_228433.1| (NC_000853) N-acetylglucosaminyl-phosphatidy... 68 2e-10 ref|NP_268794.1| (NC_002737) putative glucosyl transferase [S... 68 2e-10 emb|CAB70927.1| (AL137778) putative sugar transferase [Strept... 68 3e-10 ref|NP_302182.1| (NC_002677) putative transferase [Mycobacter... 67 7e-10 ref|NP_279218.1| (NC_002607) LPS glycosyltransferase; Lpg [Ha... 66 1e-09 gb|AAL25631.1| (AY057452) putative glycosyltransferase [Edwar... 66 1e-09 ref|NP_349652.1| (NC_003030) Glycosyltransferase [Clostridium... 63 1e-08 ref|NP_279220.1| (NC_002607) LPS biosynthesis protein; Lpb [H... 62 2e-08
Alignments
>ref|NP_495840.1| (NM_063439) phosphatidylinositol biosynthetic protein
           [Caenorhabditis elegans]
 pir||T20374 hypothetical protein D2085.6 - Caenorhabditis elegans
 emb|CAA91062.1| (Z54284) contains similarity to Pfam domain: PF00534 (Glycosyl
           transferases group 1), Score=91.6, E-value=9.5e-25,
           N=1~cDNA EST yk349e7.5 comes from this gene
           [Caenorhabditis elegans]
          Length = 444

 Score =  923 bits (2359), Expect = 0.0
 Identities = 444/444 (100%), Positives = 444/444 (100%)

Query: 1   MSLKIGPYSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSN 60
           MSLKIGPYSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSN
Sbjct: 1   MSLKIGPYSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSN 60

Query: 61  GLKVYYLPFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLM 120
           GLKVYYLPFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLM
Sbjct: 61  GLKVYYLPFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLM 120

Query: 121 GLRTVFTDHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVS 180
           GLRTVFTDHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVS
Sbjct: 121 GLRTVFTDHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVS 180

Query: 181 TIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGG 240
           TIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGG
Sbjct: 181 TIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGG 240

Query: 241 DGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAAS 300
           DGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAAS
Sbjct: 241 DGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAAS 300

Query: 301 CGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVS 360
           CGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVS
Sbjct: 301 CGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVS 360

Query: 361 KMYNWPDVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVVSCIIIFWLTVLD 420
           KMYNWPDVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVVSCIIIFWLTVLD
Sbjct: 361 KMYNWPDVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVVSCIIIFWLTVLD 420

Query: 421 LFDSPRKNGTNDKTSEKNVDPDYQ 444
           LFDSPRKNGTNDKTSEKNVDPDYQ
Sbjct: 421 LFDSPRKNGTNDKTSEKNVDPDYQ 444
>pir||A55731 GPI-anchor biosynthesis protein PIG-A - mouse
 pir||I52484 gene PIG-A protein - mouse
 dbj|BAA05047.1| (D26047) Pig-a precursor [Mus musculus]
 dbj|BAA06663.1| (D31863) PIG-A protein [Mus musculus]
          Length = 485

 Score =  439 bits (1117), Expect = e-122
 Identities = 229/447 (51%), Positives = 301/447 (67%), Gaps = 17/447 (3%)

Query: 8   YSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYL 67
           ++I +VSDFF PN GGVE+HIY L+QCLIE GH+V+ +TH YGNRKG+RYL+NGLKVYYL
Sbjct: 33  HNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVITVTHAYGNRKGVRYLTNGLKVYYL 92

Query: 68  PFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFT 127
           P  V YN +T  ++  S+P LR + +RE + IIH HS+FS++AH+ L     MGL+TVFT
Sbjct: 93  PLRVMYNQSTATTLFHSLPLLRYIFVRERITIIHSHSSFSAMAHDALFHAKTMGLQTVFT 152

Query: 128 DHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIE 187
           DHSLFGFAD S++LTNKL L  SL + +  ICVSYTSKENTVLR  L+P  VS IPNA++
Sbjct: 153 DHSLFGFADVSSVLTNKL-LTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVD 211

Query: 188 TSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIE 247
            + FTPD  +  ++  T+V + RLVYRKG DLL  I+P++C +++ + F+IGG+GPKRI 
Sbjct: 212 PTDFTPDPFRRHDSVITVVVVSRLVYRKGTDLLSGIIPELCQKYQELHFLIGGEGPKRII 271

Query: 248 LEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVS 307
           LEE+ ER++LH+RV +LG L H  V+ VL QG IF+NTSLTEAFCM+IVEAASCGL VVS
Sbjct: 272 LEEVRERYQLHDRVQLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVS 331

Query: 308 TRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPD 367
           T+VGG+PEVLP    I L EP    L D L KA+ + + G L  P   H  V   Y W +
Sbjct: 332 TKVGGIPEVLP-ESLIILCEPSVKSLCDGLEKAIFQVKSGTLPAPENIHNVVKTFYTWRN 390

Query: 368 VAARTQVIYQKAVESEPT----GRLGRLKGYYD--QGIGFGIMYIVVSCIIIF--WLTVL 419
           VA RT+ +Y++ V  E       RL RL  +     G  F ++ ++    +IF  W+T  
Sbjct: 391 VAERTEKVYER-VSKETVLPMHKRLDRLISHCGPVTGYMFALLAVLSYLFLIFLQWMTPD 449

Query: 420 DLFD------SPRKNGTNDKTSEKNVD 440
              D       PR+  T+    +K  D
Sbjct: 450 SFIDVAIDATGPRRAWTHQWPRDKKRD 476
>ref|NP_002632.1| (NM_002641) phosphatidylinositol glycan, class A isoform 1;
           Phosphatidylinositol glycan, class A; GLCNAC-PI
           synthesis protein [Homo sapiens]
 sp|P37287|PIGA_HUMAN N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein
           (GlcNac-PI synthesis protein)
           (Phosphatidylinositol-glycan biosynthesis, class A
           protein) (PIG-A)
 pir||A46217 GPI-anchor biosynthesis protein PIG-A - human
 dbj|BAA02019.1| (D11466) PIG-A protein [Homo sapiens]
 dbj|BAA05966.1| (D28791) PIG-A protein [Homo sapiens]
          Length = 484

 Score =  432 bits (1099), Expect = e-120
 Identities = 232/443 (52%), Positives = 301/443 (67%), Gaps = 16/443 (3%)

Query: 8   YSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYL 67
           ++I +VSDFF PN GGVE+HIY L+QCLIE GH+V+++TH YGNRKGIRYL++GLKVYYL
Sbjct: 33  HNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYL 92

Query: 68  PFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFT 127
           P  V YN +T  ++  S+P LR + +RE V IIH HS+FS++AH+ L     MGL+TVFT
Sbjct: 93  PLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQTVFT 152

Query: 128 DHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIE 187
           DHSLFGFAD S++LTNKL L  SL + +  ICVSYTSKENTVLR  L+P  VS IPNA++
Sbjct: 153 DHSLFGFADVSSVLTNKL-LTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVD 211

Query: 188 TSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIE 247
            + FTPD  +  ++  TIV + RLVYRKG DLL  I+P++C ++  + FIIGG+GPKRI 
Sbjct: 212 PTDFTPDPFR-RHDSITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRII 270

Query: 248 LEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVS 307
           LEE+ ER++LH+RV +LG L H  V+ VL QG IF+NTSLTEAFCM+IVEAASCGL VVS
Sbjct: 271 LEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVS 330

Query: 308 TRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPD 367
           TRVGG+PEVLP    I L EP    L + L KA+ + + G L  P   H  V   Y W +
Sbjct: 331 TRVGGIPEVLP-ENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRN 389

Query: 368 VAARTQVIYQK-AVES--EPTGRLGRLKGYYDQGIG--FGIMYIVVSCIIIF--WLTVLD 420
           VA RT+ +Y + +VE+      RL RL  +     G  F ++ +     +IF  W+T   
Sbjct: 390 VAERTEKVYDRVSVEAVLPMDKRLDRLISHCGPVTGYIFALLAVFNFLFLIFLRWMTPDS 449

Query: 421 LFD------SPRKNGTNDKTSEK 437
           + D       PR   TN+ +  K
Sbjct: 450 IIDVAIDATGPRGAWTNNYSHSK 472
>ref|NP_566874.1| (NM_114379) n-acetylglucosaminyl-phosphatidylinositol-like protein
           [Arabidopsis thaliana]
 gb|AAK62657.1| (AY039602) AT3g45100/T14D3_40 [Arabidopsis thaliana]
          Length = 447

 Score =  428 bits (1090), Expect = e-119
 Identities = 207/399 (51%), Positives = 284/399 (70%), Gaps = 5/399 (1%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPF 69
           + +VSDFF PN GGVE HIY+L+QCL++LGH+VVV+TH YGNR G+RY++ GLKVYY+P+
Sbjct: 9   VLMVSDFFFPNFGGVENHIYYLSQCLLKLGHKVVVMTHAYGNRSGVRYMTGGLKVYYVPW 68

Query: 70  IVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDH 129
                  T  ++ G++P +R +L RE + ++HGH  FS+L HE LM    MG + VFTDH
Sbjct: 69  RPFVMQTTFPTVYGTLPIVRTILRREKITVVHGHQAFSTLCHEALMHARTMGYKVVFTDH 128

Query: 130 SLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETS 189
           SL+GFAD  +I  NK VLQ+SL ++DQ ICVS+TSKENTVLR  L P KV  IPNA++T+
Sbjct: 129 SLYGFADVGSIHMNK-VLQFSLADIDQAICVSHTSKENTVLRSGLSPAKVFMIPNAVDTA 187

Query: 190 LFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELE 249
           +F P   +   +  TIV + RLVYRKGADLL E++P+VC  + +VRF++GGDGPK + LE
Sbjct: 188 MFKPASVRPSTDIITIVVISRLVYRKGADLLVEVIPEVCRLYPNVRFVVGGDGPKHVRLE 247

Query: 250 EMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTR 309
           EM E+  L +RV +LG +PH++V+ VL  G IF+N+SLTEAFC++I+EAASCGL  VSTR
Sbjct: 248 EMREKHSLQDRVEMLGAVPHSRVRSVLVTGHIFLNSSLTEAFCIAILEAASCGLLTVSTR 307

Query: 310 VGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVA 369
           VGGVPEVLP  + + L EP PDD+V A+ KA+        ++P E H  + K+Y+W DVA
Sbjct: 308 VGGVPEVLP-DDMVVLAEPDPDDMVRAIEKAISILPT---INPEEMHNRMKKLYSWQDVA 363

Query: 370 ARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVV 408
            RT+++Y +A++      L RL  +   G   G ++ +V
Sbjct: 364 KRTEIVYDRALKCSNRSLLERLMRFLSCGAWAGKLFCMV 402
>pir||T47450 n-acetylglucosaminyl-phosphatidylinositol-like protein -
           Arabidopsis thaliana
 emb|CAB72148.1| (AL138649) n-acetylglucosaminyl-phosphatidylinositol-like protein
           [Arabidopsis thaliana]
          Length = 450

 Score =  415 bits (1057), Expect = e-115
 Identities = 204/402 (50%), Positives = 282/402 (69%), Gaps = 8/402 (1%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPF 69
           + +VSDFF PN GGVE HIY+L+QCL++LGH+VVV+TH YGNR G+RY++ GLKVYY+P+
Sbjct: 9   VLMVSDFFFPNFGGVENHIYYLSQCLLKLGHKVVVMTHAYGNRSGVRYMTGGLKVYYVPW 68

Query: 70  IVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDH 129
                  T  ++ G++P +R +L RE + ++HGH  FS+L HE LM    MG + VFTDH
Sbjct: 69  RPFVMQTTFPTVYGTLPIVRTILRREKITVVHGHQAFSTLCHEALMHARTMGYKVVFTDH 128

Query: 130 SLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETS 189
           SL+GFAD  +I  NK VLQ+SL ++DQ ICVS+TSKENTVLR  L P KV  IPNA++T+
Sbjct: 129 SLYGFADVGSIHMNK-VLQFSLADIDQAICVSHTSKENTVLRSGLSPAKVFMIPNAVDTA 187

Query: 190 LFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELE 249
           +F P   +   +  TIV + RLVYRKGADLL E++P+VC  + +VRF++GGDGPK + LE
Sbjct: 188 MFKPASVRPSTDIITIVVISRLVYRKGADLLVEVIPEVCRLYPNVRFVVGGDGPKHVRLE 247

Query: 250 EMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTR 309
           EM E+  L +RV +LG +PH++V+ VL  G IF+N+SLTEAFC++I+EAASCGL  VSTR
Sbjct: 248 EMREKHSLQDRVEMLGAVPHSRVRSVLVTGHIFLNSSLTEAFCIAILEAASCGLLTVSTR 307

Query: 310 VGGV---PEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWP 366
           VGG     +VLP  + + L EP PDD+V A+ KA+        ++P E H  + K+Y+W 
Sbjct: 308 VGGFLHGLQVLP-DDMVVLAEPDPDDMVRAIEKAISILPT---INPEEMHNRMKKLYSWQ 363

Query: 367 DVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVV 408
           DVA RT+++Y +A++      L RL  +   G   G ++ +V
Sbjct: 364 DVAKRTEIVYDRALKCSNRSLLERLMRFLSCGAWAGKLFCMV 405
>pir||T40367 n-acetylglucosaminyl-phosphatidylinositol - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAB09127.1| (Z95620) n-acetylglucosaminyl-phosphatidylinositol
           [Schizosaccharomyces pombe]
          Length = 456

 Score =  376 bits (957), Expect = e-103
 Identities = 193/414 (46%), Positives = 271/414 (64%), Gaps = 13/414 (3%)

Query: 12  LVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIV 71
           +VSDFF P  GG+E+HI+ L+Q LI+LGH+V+VITH Y +R G+RYL+NGL VYY+P   
Sbjct: 1   MVSDFFFPQPGGIESHIFQLSQRLIDLGHKVIVITHAYKDRVGVRYLTNGLTVYYVPLHT 60

Query: 72  AYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSL 131
            Y   T  S     P  R +++REN++I+HGH + S L H+ ++    MGL+T FTDHSL
Sbjct: 61  VYRETTFPSFFSFFPIFRNIVIRENIEIVHGHGSLSFLCHDAILHARTMGLKTCFTDHSL 120

Query: 132 FGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLF 191
           FGFADA +I+TNKL L++++ +V+  ICVS+T +ENTVLR  L+P +VS IPNA+    F
Sbjct: 121 FGFADAGSIVTNKL-LKFTMSDVNHVICVSHTCRENTVLRAVLNPKRVSVIPNALVAENF 179

Query: 192 TPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEM 251
            PD ++   +  TIV + RL Y KG DLL  ++P++CA+H  VRF+I GDGPK I+LE+M
Sbjct: 180 QPDPSKASKDFLTIVVISRLYYNKGIDLLIAVIPRICAQHPKVRFVIAGDGPKSIDLEQM 239

Query: 252 LERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVG 311
            E++ L +RV +LG + H+QV+ V+ +G I+++ SLTEAF   +VEAASCGL+V+ST+VG
Sbjct: 240 REKYMLQDRVEMLGSVRHDQVRDVMVRGHIYLHPSLTEAFGTVLVEAASCGLYVISTKVG 299

Query: 312 GVPEVLPIGEFISLEEPVPDDLVDALLKAV----DRREKGLLMDPTEK-HEAVSKMYNWP 366
           GVPEVLP         P  DDL D L   +    D + K      TE  HE V +MY+W 
Sbjct: 300 GVPEVLP-SHMTRFARPEEDDLADTLSSVITDYLDHKIK------TETFHEEVKQMYSWI 352

Query: 367 DVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVVSCIIIFWLTVLD 420
           DVA RT+ +Y           + RLK YY  G   G ++ ++  I    + +L+
Sbjct: 353 DVAERTEKVYDSICSENNLRLIDRLKLYYGCGQWAGKLFCLLIAIDYLVMVLLE 406
>gb|AAF76891.1| (AF267484) PIG-A [Paramecium tetraurelia]
          Length = 442

 Score =  372 bits (946), Expect = e-102
 Identities = 190/420 (45%), Positives = 272/420 (64%), Gaps = 7/420 (1%)

Query: 9   SIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLP 68
           +I L+ DFF P  GGVE HI+ L  CLIE G +V++ITH Y  R G+RY++NGLKVYY P
Sbjct: 3   NICLICDFFYPCLGGVEMHIFQLGLCLIERGLKVIIITHKYQGRSGVRYMTNGLKVYYCP 62

Query: 69  FIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTD 128
           FI A     L + VG++P  R++LLRE + I+H H+  S L  E L+    MG +TVFTD
Sbjct: 63  FIPAIQTVVLFTYVGTLPIFRQILLREEIHIVHSHAATSYLGGELLLHAKSMGFKTVFTD 122

Query: 129 HSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIET 188
           HSLF F DA++   NK +L+Y L  +D +I VS+ SKEN  +R  LDP  +S IPNA++ 
Sbjct: 123 HSLFAFNDAASFHVNK-ILKYILCEIDHSISVSHVSKENLSMRASLDPRNISVIPNAVDC 181

Query: 189 SLFTPD-RNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIE 247
           S FTP+ + ++  N   IV + R+ +RKG DLL +++  +C +H  + FIIGGDGPK+  
Sbjct: 182 SRFTPNPQKRYPLNTINIVVICRMTFRKGVDLLVDVLQIICKQHPEIYFIIGGDGPKKKI 241

Query: 248 LEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVS 307
           LEE ++R+ L  +  +LG +P +QVK VLN+G IF+NTSLTEAFC++IVEAASCGL VVS
Sbjct: 242 LEETIQRYNLQNQTELLGSVPGHQVKDVLNRGHIFLNTSLTEAFCIAIVEAASCGLCVVS 301

Query: 308 TRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPD 367
           T VGG+ EVLP    +   +P P+D+   + +A+   +   +    ++HE V KMY+W  
Sbjct: 302 TNVGGISEVLP-QNMVLYADPTPEDISHKITQAIPIAKNFYVY---QQHELVKKMYSWEQ 357

Query: 368 VAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVVSCIIIFWLTVLDLFDSPRK 427
           VA RT+ +Y K ++++    L R K  Y  G  +G+  +++    + +L +LD F  P K
Sbjct: 358 VAERTEKVYYKILQTQNQTILKRFKDCYSNGQIYGLFLMILLIFDLIFLMILD-FLQPHK 416
>ref|NP_015150.2| (NC_001148) N-acetylglucosaminyl-phosphatidylinositol biosynthetic
           protein; Spt14p [Saccharomyces cerevisiae]
 sp|P32363|GPI3_YEAST N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN
           (GLCNAC-PI SYNTHESIS PROTEIN)
 emb|CAA44924.1| (X63290) trans-acting transcription factor [Saccharomyces
           cerevisiae]
          Length = 452

 Score =  365 bits (927), Expect = e-100
 Identities = 182/376 (48%), Positives = 257/376 (67%), Gaps = 10/376 (2%)

Query: 8   YSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYL 67
           ++IA++ DFF P  GGVE HIY L+Q LI+LGH VV+ITH Y +R G+R+L+NGLKVY++
Sbjct: 3   FNIAMLCDFFYPQLGGVEFHIYHLSQKLIDLGHSVVIITHAYKDRVGVRHLTNGLKVYHV 62

Query: 68  PFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFT 127
           PF V +   T  ++  + P +R +LLRE +QI+H H + S+ AHE ++    MGLRTVFT
Sbjct: 63  PFFVIFRETTFPTVFSTFPIIRNILLREQIQIVHSHGSASTFAHEGILHANTMGLRTVFT 122

Query: 128 DHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIE 187
           DHSL+GF + ++I  NKL L ++L N+D+ ICVS T KEN ++R +L P+ +S IPNA+ 
Sbjct: 123 DHSLYGFNNLTSIWVNKL-LTFTLTNIDRVICVSNTCKENMIVRTELSPDIISVIPNAVV 181

Query: 188 TSLFTP------DRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGD 241
           +  F P       + +   +   IV +GRL   KG+DLL  I+PKVC+ H+ V FI+ GD
Sbjct: 182 SEDFKPRDPTGGTKRKQSRDKIVIVVIGRLFPNKGSDLLTRIIPKVCSSHEDVEFIVAGD 241

Query: 242 GPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASC 301
           GPK I+ ++M+E  +L +RV +LG +PH +V+ VL QG I+++ SLTEAF   +VEAASC
Sbjct: 242 GPKFIDFQQMIESHRLQKRVQLLGSVPHEKVRDVLCQGDIYLHASLTEAFGTILVEAASC 301

Query: 302 GLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVD-RREKGLLMDPTEKHEAVS 360
            L +V+T+VGG+PEVLP    +  E+    DLV A  KA++  R K L  D +  H++VS
Sbjct: 302 NLLIVTTQVGGIPEVLPNEMTVYAEQTSVSDLVQATNKAINIIRSKAL--DTSSFHDSVS 359

Query: 361 KMYNWPDVAARTQVIY 376
           KMY+W DVA RT  IY
Sbjct: 360 KMYDWMDVAKRTVEIY 375
>pir||S65187 GPI-anchor biosynthesis protein PIG-A - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97882.1| (Z73531) ORF YPL175w [Saccharomyces cerevisiae]
          Length = 461

 Score =  360 bits (916), Expect = 2e-98
 Identities = 180/372 (48%), Positives = 253/372 (67%), Gaps = 10/372 (2%)

Query: 12  LVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIV 71
           ++ DFF P  GGVE HIY L+Q LI+LGH VV+ITH Y +R G+R+L+NGLKVY++PF V
Sbjct: 16  MLCDFFYPQLGGVEFHIYHLSQKLIDLGHSVVIITHAYKDRVGVRHLTNGLKVYHVPFFV 75

Query: 72  AYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSL 131
            +   T  ++  + P +R +LLRE +QI+H H + S+ AHE ++    MGLRTVFTDHSL
Sbjct: 76  IFRETTFPTVFSTFPIIRNILLREQIQIVHSHGSASTFAHEGILHANTMGLRTVFTDHSL 135

Query: 132 FGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLF 191
           +GF + ++I  NKL L ++L N+D+ ICVS T KEN ++R +L P+ +S IPNA+ +  F
Sbjct: 136 YGFNNLTSIWVNKL-LTFTLTNIDRVICVSNTCKENMIVRTELSPDIISVIPNAVVSEDF 194

Query: 192 TP------DRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKR 245
            P       + +   +   IV +GRL   KG+DLL  I+PKVC+ H+ V FI+ GDGPK 
Sbjct: 195 KPRDPTGGTKRKQSRDKIVIVVIGRLFPNKGSDLLTRIIPKVCSSHEDVEFIVAGDGPKF 254

Query: 246 IELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHV 305
           I+ ++M+E  +L +RV +LG +PH +V+ VL QG I+++ SLTEAF   +VEAASC L +
Sbjct: 255 IDFQQMIESHRLQKRVQLLGSVPHEKVRDVLCQGDIYLHASLTEAFGTILVEAASCNLLI 314

Query: 306 VSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVD-RREKGLLMDPTEKHEAVSKMYN 364
           V+T+VGG+PEVLP    +  E+    DLV A  KA++  R K L  D +  H++VSKMY+
Sbjct: 315 VTTQVGGIPEVLPNEMTVYAEQTSVSDLVQATNKAINIIRSKAL--DTSSFHDSVSKMYD 372

Query: 365 WPDVAARTQVIY 376
           W DVA RT  IY
Sbjct: 373 WMDVAKRTVEIY 384
>gb|AAF57802.1| (AE003802) CG6401 gene product [Drosophila melanogaster]
          Length = 479

 Score =  360 bits (915), Expect = 2e-98
 Identities = 185/320 (57%), Positives = 235/320 (72%), Gaps = 4/320 (1%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPF 69
           I +VSDFF P+ GGVE H+Y L+Q L+ LGH++VV+TH YG+  GIRY++  LKVYYLP 
Sbjct: 3   ICMVSDFFYPSIGGVEEHVYNLSQMLLSLGHKIVVLTHAYGDCSGIRYVTGYLKVYYLPI 62

Query: 70  IVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDH 129
            V YN   L + V ++P LR VLLRE V+++HGHS FS+LAHE LM+G L+GL+TVFTDH
Sbjct: 63  KVCYNQCILPTAVCNVPMLRAVLLRERVEVVHGHSAFSALAHEALMVGSLLGLKTVFTDH 122

Query: 130 SLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETS 189
           SLFGFAD SA LTN L L+ +L  V+  ICVS+  KENTVLR ++  ++VS IPNA++T+
Sbjct: 123 SLFGFADLSAALTNNL-LEVNLGMVNHAICVSHIGKENTVLRARVAKHRVSVIPNAVDTA 181

Query: 190 LFTPDRNQF-FNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIEL 248
           LFTPD  Q   N+   IV   RLVYRKG DLL  I+P+      ++ FII GDGPKR  L
Sbjct: 182 LFTPDPQQRPSNDIINIVVASRLVYRKGIDLLAGIIPRF-KNTPNINFIIVGDGPKRDLL 240

Query: 249 EEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVST 308
           EE+ E+  + ERV ++G + HN+V+  L +G IF+NTSLTEA+CM+IVEAASCGL VVST
Sbjct: 241 EEIREKTNMQERVQMVGAVEHNRVRDFLVRGHIFLNTSLTEAYCMAIVEAASCGLQVVST 300

Query: 309 RVGGVPEVLPIGEFISLEEP 328
            VGG+PEVLP    I L EP
Sbjct: 301 SVGGIPEVLP-KSLILLAEP 319
 Score = 34.1 bits (77), Expect = 4.8
 Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 5/80 (6%)

Query: 349 LMDPTEKHEAVSKMYNWPDVAARTQVIYQKAVESEPTGRLGRLKGYYDQGIGFGIMYIVV 408
           +M P   +E V  +YNW DVA RT  +Y + +          +   +  G  F + ++V 
Sbjct: 393 VMCPYRCNELVETLYNWEDVALRTVKVYDRVLNERSFTTSELVFAVWQHGSWFLVFFVVA 452

Query: 409 SCIIIFWLTVLDLFDSPRKN 428
                F + +L+L+  PRK+
Sbjct: 453 H----FLMRLLELW-RPRKH 467
>prf||1804343A SPT14 gene [Saccharomyces cerevisiae]
          Length = 415

 Score =  358 bits (910), Expect = 1e-97
 Identities = 180/372 (48%), Positives = 253/372 (67%), Gaps = 10/372 (2%)

Query: 12  LVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIV 71
           ++ DFF P  GGVE HIY L+Q LI+LGH VV+ITH Y +R G+R+L+NGLKVY++PF V
Sbjct: 1   MLCDFFYPQLGGVEFHIYHLSQKLIDLGHSVVIITHAYKDRVGVRHLTNGLKVYHVPFFV 60

Query: 72  AYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSL 131
            +   T  ++  + P +R +LLRE +QI+H H + S+ AHE ++    MGLRTVFTDHSL
Sbjct: 61  IFRETTFPTVFSTFPIIRNILLREQIQIVHSHGSASTFAHEGILHANTMGLRTVFTDHSL 120

Query: 132 FGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLF 191
           +GF + ++I  NKL L ++L N+D+ ICVS T KEN ++R +L P+ +S IPNA+ +  F
Sbjct: 121 YGFNNLTSIWVNKL-LTFTLTNIDRVICVSNTCKENMIVRTELSPDIISVIPNAVVSEDF 179

Query: 192 TP------DRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKR 245
            P       + +   +   IV +GRL   KG+DLL  I+PKVC+ H+ V FI+ GDGPK 
Sbjct: 180 KPRDPTGGTKRKQSRDKIVIVVIGRLFPNKGSDLLTRIIPKVCSSHEDVEFIVAGDGPKF 239

Query: 246 IELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHV 305
           I+ ++M+E  +L +RV +LG +PH +V+ VL QG I+++ SLTEAF   +VEAASC L +
Sbjct: 240 IDFQQMIESHRLQKRVQLLGSVPHEKVRDVLCQGDIYLHASLTEAFGTILVEAASCNLLI 299

Query: 306 VSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVD-RREKGLLMDPTEKHEAVSKMYN 364
           V+T+VGG+PEVLP    +  E+    DLV A  KA++  R K L  D +  H++VSKMY+
Sbjct: 300 VTTQVGGIPEVLPNEMTVYAEQTSVSDLVQATNKAINIIRSKAL--DTSSFHDSVSKMYD 357

Query: 365 WPDVAARTQVIY 376
           W DVA RT  IY
Sbjct: 358 WMDVAKRTVEIY 369
>ref|XP_045453.1| (XM_045453) similar to phosphatidylinositol glycan, class A isoform
           1; Phosphatidylinositol glycan, class A; GLCNAC-PI
           synthesis protein [Homo sapiens]
          Length = 280

 Score =  227 bits (574), Expect = 3e-58
 Identities = 116/229 (50%), Positives = 154/229 (66%), Gaps = 3/229 (1%)

Query: 8   YSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYL 67
           ++I + SDFF PN GGVE+HIY L QCLI  G +V+++ H YGNRKGIRYL+N LKVYYL
Sbjct: 33  HNICMASDFFYPNMGGVESHIYQLPQCLIGRGDKVIIVIHAYGNRKGIRYLTNDLKVYYL 92

Query: 68  PFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFT 127
           P  V YN +   ++  S+P L+ + ++E V IIH HS+FS++AH+ L     MGL+TV T
Sbjct: 93  PLKVMYNQSMAMTLFHSLPLLKYIFVQERVTIIHSHSSFSAMAHDVLFHAKTMGLQTVLT 152

Query: 128 DHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIE 187
           DH L GFA   ++LTNKL L  SL +  + ICVSYTSKENTVLR  L    VS IPNA++
Sbjct: 153 DHPLSGFAKVHSVLTNKL-LTVSLCDTSRIICVSYTSKENTVLRAALITEIVSVIPNAVD 211

Query: 188 TSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRF 236
              FTPD   F  + +  + + RLVYRKG +L+  I+PK+ +     +F
Sbjct: 212 PIDFTPD--PFRRHDSITIVVSRLVYRKGTNLVSGIIPKLLSEILRFKF 258
>emb|CAB57276.1| (X77725) PIG-A [Homo sapiens]
          Length = 248

 Score =  176 bits (443), Expect = 6e-43
 Identities = 91/167 (54%), Positives = 115/167 (68%), Gaps = 3/167 (1%)

Query: 214 RKG--ADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQ 271
           RKG   DLL  I+P++C ++  + FIIGG+GPKRI LEE+ ER++LH+RV +LG L H  
Sbjct: 77  RKGIRIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKD 136

Query: 272 VKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPD 331
           V+ VL QG IF+NTSLTEAFCM+IVEAASCGL VVSTRVGG+PEVLP    I L EP   
Sbjct: 137 VRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLP-ENLIILCEPSVK 195

Query: 332 DLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQK 378
            L + L KA+ + + G L  P   H  V   Y W +VA RT+ +Y +
Sbjct: 196 SLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDR 242
 Score = 82.8 bits (202), Expect = 1e-14
 Identities = 34/49 (69%), Positives = 43/49 (87%)

Query: 8  YSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIR 56
          ++I +VSDFF PN GGVE+HIY L+QCLIE GH+V+++TH YGNRKGIR
Sbjct: 33 HNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIR 81
>pir||I52665 class A GlcNAc-inositol phospholipid assembly protein PIG-A - human
 gb|AAD14160.1|S74936_1 (S74936) class A GlcNAc-inositol phospholipid assembly protein
           [Homo sapiens]
          Length = 315

 Score =  126 bits (315), Expect = 5e-28
 Identities = 83/191 (43%), Positives = 107/191 (55%), Gaps = 14/191 (7%)

Query: 260 RVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPI 319
           RV +LG L H  V+ VL QG IF+NTSLTEAFCM+IVEAASCGL VVSTRVGG+PEVLP 
Sbjct: 114 RVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLP- 172

Query: 320 GEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQK- 378
              I L EP    L + L KA+ + + G L  P   H  V   Y W +VA RT+ +Y + 
Sbjct: 173 ENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRV 232

Query: 379 AVES--EPTGRLGRLKGYYDQGIG--FGIMYIVVSCIIIF--WLTVLDLFD------SPR 426
           +VE+      RL RL  +     G  F ++ +     +IF  W+T   + D       PR
Sbjct: 233 SVEAVLPMDKRLDRLISHCGPVTGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPR 292

Query: 427 KNGTNDKTSEK 437
              TN+ +  K
Sbjct: 293 GAWTNNYSHSK 303
 Score =  121 bits (300), Expect = 4e-26
 Identities = 54/86 (62%), Positives = 69/86 (79%)

Query: 8   YSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYL 67
           ++I +VSDFF PN GGVE+HIY L+QCLIE GH+V+++TH YGNRKGIRYL++GLKVYYL
Sbjct: 33  HNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYL 92

Query: 68  PFIVAYNGATLGSIVGSMPWLRKVLL 93
           P  V YN +T  ++  S+P LR  LL
Sbjct: 93  PLKVMYNQSTATTLFHSLPLLRVRLL 118
>ref|NP_065205.1| (NM_020472) phosphatidylinositol glycan, class A isoform 2;
           Phosphatidylinositol glycan, class A; GLCNAC-PI
           synthesis protein [Homo sapiens]
          Length = 118

 Score =  119 bits (296), Expect = 9e-26
 Identities = 52/82 (63%), Positives = 67/82 (81%)

Query: 8   YSIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYL 67
           ++I +VSDFF PN GGVE+HIY L+QCLIE GH+V+++TH YGNRKGIRYL++GLKVYYL
Sbjct: 33  HNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYL 92

Query: 68  PFIVAYNGATLGSIVGSMPWLR 89
           P  V YN +T  ++  S+P LR
Sbjct: 93  PLKVMYNQSTATTLFHSLPLLR 114
>ref|NP_126928.1| (NC_000868) GALACTOSYLTRANSFERASE or LPS BIOSYNTHESIS RFBU RELATED
           PROTEIN [Pyrococcus abyssi]
 pir||A75033 probable hexosyltransferase (EC 2.4.1.-) PAB0827 [similarity] -
           Pyrococcus abyssi (strain Orsay)
 emb|CAB50158.1| (AJ248287) GALACTOSYLTRANSFERASE or LPS BIOSYNTHESIS RFBU RELATED
           PROTEIN [Pyrococcus abyssi]
          Length = 371

 Score =  111 bits (276), Expect = 2e-23
 Identities = 97/370 (26%), Positives = 177/370 (47%), Gaps = 16/370 (4%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPF 69
           IALVSD++ P  GGV  H++ LA  L ++GH V ++T+   N K       G+ +  +P 
Sbjct: 6   IALVSDWYFPKIGGVAIHVHNLAIHLRKMGHEVSIVTNALTNGKEGELQKYGIDLIKVPG 65

Query: 70  IVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDH 129
           ++  +G  L  I  S   L + L  +   ++H    F+ L+ +++  G  +G  T+ T+H
Sbjct: 66  LIK-DGINLSMIAKSSNSLVEYL--KGFDVVHAQHAFTPLSLKSIPAGNKVGALTLVTNH 122

Query: 130 SLFGFADASAILT--NKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIE 187
           S+  F + S IL   +K+   Y  + + Q       SK +     K     +  IPN + 
Sbjct: 123 SV-EFENFS-ILNGFSKMSYSYFKMYLGQVKVGIGVSKASVSFLRKFTNAPIVEIPNGVN 180

Query: 188 TSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIE 247
              F     ++      I+++GRL  RKG + L   +  V       +  I GDG  R  
Sbjct: 181 IERFNGRGREW--GTRNILYVGRLEPRKGVNYLISAMKFV-----EGKLTIVGDGSMRKV 233

Query: 248 LEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVS 307
           L+   ++  + ++V  LG +   ++  +  + ++F+  SL+EAF + ++EA +  + V+ 
Sbjct: 234 LKMQAKKLGVEDKVEFLGFISQEELILLYKKSEVFVLPSLSEAFGIVLLEAMASEVPVIG 293

Query: 308 TRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPD 367
           T VGG+PE+  IG+   +  P     +   + A+   +K          + V ++Y+W  
Sbjct: 294 TSVGGIPEI--IGDAGIIVPPRDSKALANAINAILSNQKTAKRLGKLGRKRVERLYSWDV 351

Query: 368 VAARTQVIYQ 377
           VA RT+ +Y+
Sbjct: 352 VAERTERLYR 361
>ref|NP_143674.1| (NC_000961) hypothetical protein [Pyrococcus horikoshii]
 pir||F71196 probable hexosyltransferase (EC 2.4.1.-) PH1844 - Pyrococcus
           horikoshii
 dbj|BAA30965.1| (AP000007) 381aa long hypothetical protein [Pyrococcus horikoshii]
          Length = 381

 Score =  107 bits (265), Expect = 4e-22
 Identities = 103/397 (25%), Positives = 181/397 (44%), Gaps = 48/397 (12%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPF 69
           IALVSD++ P  GGV TH++ LA  L E GH V ++T+     K       G+++  +P 
Sbjct: 6   IALVSDWYYPKIGGVATHMHNLAIKLRERGHEVGIVTNNRPTGKEEELKRYGIELIKIPG 65

Query: 70  IVA-YNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTD 128
           I++ +    L   + S   L + L  ++  IIH H  F+ L+ + L  G  M   T+ T 
Sbjct: 66  IISPFLDVNLTYGLKSSEELNEFL--KDFDIIHSHHAFTPLSLKALKAGKNMEKGTLLTT 123

Query: 129 HSLFGFADASAILTN--------KLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVS 180
           HS+  FA  S +           K  L+YS     + I VS  +K             V 
Sbjct: 124 HSI-SFAHESKLWDTLGFTIPLFKSYLKYS----HRIIAVSKAAKS---FIEHFTSVPVL 175

Query: 181 TIPNAIETSLFTPDRN------QFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSV 234
            +PN ++   F P R+      +F      ++++ R+ YRKG  +L     K+    +  
Sbjct: 176 IVPNGVDDERFFPARDKEKIKAKFGLEGNVVLYVSRMSYRKGPHVLLNAFSKI----EDA 231

Query: 235 RFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSL-TEAFCM 293
             ++ G+G     L+   +   +  +VV +G +P + +  V     +F+  S+ +EAF +
Sbjct: 232 TLVMVGNGEMLPFLKAQTKFLGIENKVVFMGYVPDDILPEVFRMADVFVLPSISSEAFGI 291

Query: 294 SIVEAASCGLHVVSTRVGGVPEVL---------PIGEFISLEEPVPDDLVDALLKAVDRR 344
            I+EA + G+ +++T VGG+PEV+         P G  + L E      ++ LLK  + R
Sbjct: 292 VILEAMASGVPIIATDVGGIPEVIKENSAGLLVPPGNELKLREA-----IEKLLKNEELR 346

Query: 345 EKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQKAVE 381
           +            +V + Y+W  +  + + IY + ++
Sbjct: 347 K----WYGNNGRRSVEEKYSWNKIVVKIERIYNEVLQ 379
>ref|NP_228553.1| (NC_000853) conserved hypothetical protein [Thermotoga maritima]
 pir||C72340 probable hexosyltransferase (EC 2.4.1.-) TM0744 - Thermotoga
           maritima (strain MSB8)
 gb|AAD35825.1|AE001744_15 (AE001744) conserved hypothetical protein [Thermotoga maritima]
          Length = 406

 Score =   99 bits (246), Expect = 7e-20
 Identities = 100/387 (25%), Positives = 170/387 (43%), Gaps = 24/387 (6%)

Query: 9   SIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLP 68
           +IA+ SD + P   GV T I    + L E GH+VVV+       +   ++   +   + P
Sbjct: 2   NIAMFSDTYAPQINGVATSIRVYKKKLTERGHKVVVVAPSAPEEEKDVFVVRSIPFPFEP 61

Query: 69  FIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTD 128
                +  ++ S    + ++R+     NVQIIH HS F  +  + L +   MGL  V T 
Sbjct: 62  ----QHRISIASTKNILEFMRE----NNVQIIHSHSPF-FIGFKALRVQEEMGLPHVHTY 112

Query: 129 HSLF----GFADASAILTNKLVLQYSLINVDQT-ICVSYTSKENTVLRGKLDPNKVSTIP 183
           H+L      +         +LV  +S    + T + ++ T      L        +  +P
Sbjct: 113 HTLLPEYRHYIPKPFTPPKRLVEHFSAWFCNMTNVVIAPTEDIKRELESYGVKRPIEVLP 172

Query: 184 NAIETSLF---TPDRNQFFNNP---TTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFI 237
             IE   F    P+  +   NP     +++ GR+   K  D L  +   + A    + FI
Sbjct: 173 TGIEVEKFEVEAPEELKRKWNPEGKKVVLYAGRIAKEKNLDFLLRVFESLNA--PGIAFI 230

Query: 238 IGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVE 297
           + GDGP+R E+EE  +   L  +  I G +PH+++      G +F+  S TE   + ++E
Sbjct: 231 MVGDGPEREEVEEFAKEKGLDLK--ITGFVPHDEIPLYYKLGDVFVFASKTETQGLVLLE 288

Query: 298 AASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHE 357
           A + GL VV+ +  GV +VL   E   L E   + L    +K + + ++      T+  E
Sbjct: 289 ALASGLPVVALKWKGVKDVLKNCEAAVLIEEENERLFAEKIKHILKNDRLREELSTKGRE 348

Query: 358 AVSKMYNWPDVAARTQVIYQKAVESEP 384
            V K ++      R + IY +A+E  P
Sbjct: 349 FVRKEWSVDRFVQRLEEIYTRAIEEGP 375
>ref|NP_275316.1| (NC_000916) LPS biosynthesis RfbU related protein
           [Methanothermobacter thermautotrophicus]
 pir||C69098 probable hexosyltransferase (EC 2.4.1.-) MTH173 - Methanobacterium
           thermoautotrophicum (strain Delta H)
 gb|AAB84679.1| (AE000805) LPS biosynthesis RfbU related protein
           [Methanothermobacter thermautotrophicus]
          Length = 382

 Score = 94.9 bits (233), Expect = 2e-18
 Identities = 96/340 (28%), Positives = 155/340 (45%), Gaps = 32/340 (9%)

Query: 5   IGPYSIALVSDFFCPN-AGGVETHIYFLAQCLIELGHRVVVIT---HGYGNRKGIRYLSN 60
           +GP  I +VSDFF P+  GG E   + +A+ L+E GH V VI+   HG G  + +    +
Sbjct: 1   MGPMRILIVSDFFVPHYNGGGERRYFEIARRLVERGHVVDVISMGIHGVGEYEEV----S 56

Query: 61  GLKVYYL-PFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHST-------FSSLAHE 112
           G++V++L P I           +  M    + ++  +  II   +         +S  H 
Sbjct: 57  GVRVHHLGPRIRKPPLRGPLDFIRFMAAAFRWVMTHDYDIIDAQTYAPLLPAFLASRIHG 116

Query: 113 TLMIGGLMGLRTVFTDHSLFGFADASAILTNKLVLQYSLINVDQTICVS-YTSKENTVLR 171
           T M+  +  + +   D  L     A+ +    + L Y     D  I VS  T+   T L 
Sbjct: 117 TPMVATIHDVSSAHGDQWLQSSKTATILERVLMRLPY-----DGVITVSRSTASALTELH 171

Query: 172 GKLDPNKVSTIPNAIETSLF---TPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVC 228
           G+ +P+ +  IPN ++  L    TP    +      I+F+GRL   K  D L E+  K+ 
Sbjct: 172 GR-NPDGIHIIPNGVDPELIDSVTPATGNY------IIFVGRLAPHKHVDHLIEVFSKLV 224

Query: 229 ARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLT 288
                +R  I GDG +R  L+ M++   + + V     L + +V   +   ++ +  S  
Sbjct: 225 IDFPDLRLEIIGDGVERARLKAMVDECGIRDSVTFHHNLSYPEVISRIRGARVLVLPSTR 284

Query: 289 EAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEP 328
           E F M + EA +CG+  V+ R GGV EV+  GE   L EP
Sbjct: 285 EGFGMVLAEAGACGVPAVAYRSGGVVEVIDDGENGFLVEP 324
>gb|AAL81485.1| (AE010240) glycosyl transferase [Pyrococcus furiosus DSM 3638]
          Length = 383

 Score = 94.1 bits (231), Expect = 4e-18
 Identities = 95/352 (26%), Positives = 160/352 (44%), Gaps = 35/352 (9%)

Query: 49  YGNRKGIR-YLSNGLKVYYLPFI---VAYNGATLGSIVGSMPWLRKVLLRENV--QIIHG 102
           YG +  ++ Y    + VYY  FI   + Y    LG        + KV+ REN+  +I H 
Sbjct: 48  YGYKMFLKDYSYENVYVYYPRFIHFPIGYFRRRLGE--NYYKTILKVIKRENLKFKIAHA 105

Query: 103 HSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASAILTNKLVLQY----SLINVDQTI 158
           H T+ S  + T ++     +  V T H L      + +L N  +  +    ++INV +  
Sbjct: 106 HFTWPS-GYATHILKRTHKIPFVVTTHGLHD-TRMNFLLKNGAMEVWKSADAIINVSRK- 162

Query: 159 CVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQFFNNPTTI-------VFLGRL 211
           CV        ++R  +  +K+  IPN ++TSLF P           I       + +G L
Sbjct: 163 CVKL------LMRVGIPEDKLYYIPNGVDTSLFYPQETALIRKELNIPIDKKILISVGNL 216

Query: 212 VYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQ 271
           V +KG + L   +  +      V   I G+GP R  LE +    KL E V ++G  PH  
Sbjct: 217 VEKKGFEYLIRAMKIILHARDDVLLYIIGEGPLRKRLENITRELKLEEHVFLVGPKPHRD 276

Query: 272 VKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPV-P 330
           +   +N G +F+  SL E F +  +EA +CG  V+ST  GG  EV+   E+  L  P  P
Sbjct: 277 IPLWINAGDLFVLPSLVENFGVVNIEALACGKPVISTINGGSEEVITSEEYGLLCPPRDP 336

Query: 331 DDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQKAVES 382
           + L + +L A+++          EK    ++ ++W ++A +   +Y+  + +
Sbjct: 337 ECLAEKILMALNKEWD------REKIRKYAEQFDWRNIARQIFKVYEDVLSN 382
>ref|NP_266369.1| (NC_002662) LPS biosynthesis protein [Lactococcus lactis subsp.
           lactis]
 gb|AAK04311.1|AE006259_5 (AE006259) LPS biosynthesis protein [Lactococcus lactis subsp.
           lactis]
          Length = 379

 Score = 94.1 bits (231), Expect = 4e-18
 Identities = 82/363 (22%), Positives = 165/363 (44%), Gaps = 40/363 (11%)

Query: 9   SIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLP 68
           ++A+ + ++ P+ GGVE + Y +A+ L E G+RV++IT  +        +  G+K+Y LP
Sbjct: 5   TVAIFNGYYIPHLGGVERYTYNIAKKLTEKGYRVIIITTQHDENLTNEEIQEGIKIYRLP 64

Query: 69  FIVAYNGATLGSIVGSMPWLRKVLLREN-VQIIHGHSTFSSLAHETLMIGGLMGLR---- 123
               +            P+L+K  +  + ++ I   S    +A+    +  ++G++    
Sbjct: 65  IKNLWK--------NRYPFLKKNRIYHSLIEKIEAESIDYYVANTRFHLPAMLGVKMAKA 116

Query: 124 ----TVFTDHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRG------- 172
                +  +H       +S +  N  VL + L  ++Q + +    K+ ++  G       
Sbjct: 117 KGKEAIVIEHG------SSYLTLNNPVLDFMLRKIEQLL-IGRVKKDTSLFYGVSNEASE 169

Query: 173 ---KLDPNKVSTIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYR-KGADLLCEIVPKVC 228
                D      +PNA+    +   + +      TI + GRL+ + KG ++L     K+ 
Sbjct: 170 WLKTFDIKAKGVLPNAVAVDEYFNQKIEKDEKKLTISYAGRLIPQMKGVEILLSTFSKLS 229

Query: 229 ARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLT 288
              K++  II GDGP    L E+  ++   + +  LG +P+ +V  +  +  +F+  S +
Sbjct: 230 KERKNLELIIAGDGPL---LNEVKRKYS-QKNIKFLGYVPYEKVLEIDAKSDVFVLMSRS 285

Query: 289 EAFCMSIVEAASCGLHVVST-RVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKG 347
           E F  +++EAA     +++T  VGG  +++P   +  + E     L + L K +D +E  
Sbjct: 286 EGFATAMLEAAMLENVIITTPTVGGARDIMPDETYGYIIENNETKLFETLTKVLDNKEHM 345

Query: 348 LLM 350
            LM
Sbjct: 346 RLM 348
>ref|NP_148357.1| (NC_000854) N-acetylglucosaminyl-phosphatidylinositol biosynthetic
           protein [Aeropyrum pernix]
 pir||D72511 probable hexosyltransferase (EC 2.4.1.-) APE2066 [similarity] -
           Aeropyrum pernix (strain K1)
 dbj|BAA81076.1| (AP000063) 392aa long hypothetical
           N-acetylglucosaminyl-phosphatidylinositol biosynthetic
           protein [Aeropyrum pernix]
          Length = 392

 Score = 93.7 bits (230), Expect = 5e-18
 Identities = 94/381 (24%), Positives = 178/381 (46%), Gaps = 20/381 (5%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITH--GYGNRKGIRYLSNGLKVYYL 67
           I +V DF   + GGV++H+  L + L + G+ VV+++   G G+ K +    + +     
Sbjct: 22  IVMVMDFHPSSVGGVQSHVRDLTRLLQDFGYDVVIVSRALGKGDVKDLEAEGHYIVKPLF 81

Query: 68  PFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFT 127
           P  + +       +      LR+ +      ++H H  ++  +   L     +GL  + T
Sbjct: 82  PLEIIF-------VPPDPSDLRREIESLKPDVVHSHHIYTLTSLLALKAARDLGLPRIAT 134

Query: 128 DHSLFGFADASA---ILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPN 184
           +HS+F   D  A   I +  L  +Y L N    I VS T+ +  V     D      IPN
Sbjct: 135 NHSIFLAYDKVALWRIASIVLPTRYLLPNAQAVISVS-TAADKMVEGIVGDSVDRYIIPN 193

Query: 185 AIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPK 244
            ++   F P   +   +   ++FLGRLV+RKGA +L      V    +  +  IGG G  
Sbjct: 194 GVDVERFKPSTPK--ADYPLVLFLGRLVWRKGAHVLVRAFRHVVDEIRDAKLYIGGKGEF 251

Query: 245 RIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIF-INTSLTEAFCMSIVEAASCGL 303
              ++ ++ R+ L   V +LG++P ++   + +   +  + + + E+F +  +E+ S G 
Sbjct: 252 EPIIKLLIARYGLENNVKMLGVVPESEKPSLYSSAWVTAVPSIVNESFGIVALESLSSGT 311

Query: 304 HVVSTRVGGVPEVLPIGEFISLEEP-VPDDLVDALLKAVDRREKGLLMDPTEK-HEAVSK 361
            VV++R GG+ +V+  G+   L +P    +L  AL+  +  ++ GL    +E+  + V +
Sbjct: 312 PVVASRQGGLKDVVKHGKTGLLVKPGSSKELAKALITLL--QDSGLRKRMSEEARKIVLE 369

Query: 362 MYNWPDVAARTQVIYQKAVES 382
            Y+W  V  +   +Y   +E+
Sbjct: 370 RYDWRKVVPQILKVYGHYMEA 390
>ref|NP_437172.1| (NC_003078) putative membrane-anchored glycosyltransferase protein
           [Sinorhizobium meliloti]
 emb|CAC49032.1| (AL603644) putative membrane-anchored glycosyltransferase protein
           [Sinorhizobium meliloti]
          Length = 416

 Score = 86.3 bits (211), Expect = 8e-16
 Identities = 64/239 (26%), Positives = 109/239 (44%), Gaps = 39/239 (16%)

Query: 176 PNKVSTIPNAIETSLFTPDRNQFFNNPTT---IVFLGRLVYRKGADLLCEIVPKVCARHK 232
           P  V+++ N ++   F P       +  T   I+F+GR+   KG   L E   +V  R  
Sbjct: 178 PGAVASVGNGVDVFHFRPSEAGASGDARTGRVILFVGRISPEKGLHTLVEAFSEVALRFP 237

Query: 233 SVRFIIGG--------------DGPKRIE----------------LEEMLERFKLHERVV 262
            V   I G                P+ ++                L+E+++R +L  R+ 
Sbjct: 238 DVELRIAGPYSPLPVDFLTSLSSDPRVLDLKRFYDQWNRCRYQQHLDELMDRHRLRHRIR 297

Query: 263 ILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEF 322
            LG + H ++    +   I +N SL+E+F +S+VE  +CG+ VV TRVGG+ E +  G  
Sbjct: 298 FLGNVSHKELVAAYHDADIVVNPSLSESFGISVVEGMACGIPVVGTRVGGMCESILDGHT 357

Query: 323 -ISLEEPVPDDLVDALLKAVD--RREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQK 378
            + +E   P +L  AL+  +D   R +G+    TE  E    +Y+W   A R + +Y++
Sbjct: 358 GMLVEADAPGELSQALITVLDDPARARGM---GTEGRERAVALYSWEARAERLRSVYER 413
>gb|AAL82009.1| (AE010283) glycosyl transferase [Pyrococcus furiosus DSM 3638]
          Length = 358

 Score = 86.3 bits (211), Expect = 1e-15
 Identities = 97/380 (25%), Positives = 163/380 (42%), Gaps = 53/380 (13%)

Query: 31  LAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIVA---YNGATLGSIVGSMPW 87
           LA  L E GH V ++T+     K       G+ +  +P +V+       T G        
Sbjct: 4   LAIKLRERGHEVGIVTNNRVTGKEKELEKYGIDLIKIPGVVSPLLEVNITYG-------- 55

Query: 88  LRKVLLRE---NVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASAI---- 140
           L+   L E   N  +IH H  F  LA + +  G  M   T+ T HS+  FA  S +    
Sbjct: 56  LKSSELNEFLNNFDVIHSHHAFMPLALKAVKAGRTMEKATLLTTHSI-SFAHESKLWDTL 114

Query: 141 -LTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPDRN--- 196
            LT  L   Y L    + I VS  +K             VS +PN ++ + F P ++   
Sbjct: 115 GLTIPLFRSY-LKYPHRIIAVSKAAKS---FIEHFTSVSVSIVPNGVDDTRFFPAKHKDK 170

Query: 197 ---QFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLE 253
              +F      ++++ R+ YRKG  +L     K+    +    ++ G G     L+   +
Sbjct: 171 IKAKFGLEGNIVLYVSRMSYRKGPHVLLNAFSKI----EDATLVMVGSGEMLPFLKAQAK 226

Query: 254 RFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLT-EAFCMSIVEAASCGLHVVSTRVGG 312
              + ERVV +G +P + +  V     +F+  S++ EAF + ++EA + G+ VV+T VGG
Sbjct: 227 FLGIEERVVFMGYVPDDALPEVFRMADVFVLPSVSAEAFGIVVLEAMASGVPVVATDVGG 286

Query: 313 VPEVL---------PIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMY 363
           +PE++         P G  + L E     L +  L    R+  G+        +AV + Y
Sbjct: 287 IPEIIKENEAGLLVPPGNELKLREATQKLLKNEEL----RKWYGM-----NGRKAVEEKY 337

Query: 364 NWPDVAARTQVIYQKAVESE 383
           +W  +    + IY + +E +
Sbjct: 338 SWDKIVVEIERIYSEVLEEQ 357
>ref|NP_472029.1| (NC_003212) weakly similar to human
           N-acetylglucosaminyl-phosphatidylinositol biosynthetic
           protein [Listeria innocua]
 emb|CAC97926.1| (AL596173) weakly similar to human
           N-acetylglucosaminyl-phosphatidylinositol biosynthetic
           protein [Listeria innocua]
          Length = 427

 Score = 85.2 bits (208), Expect = 2e-15
 Identities = 81/326 (24%), Positives = 139/326 (41%), Gaps = 39/326 (11%)

Query: 9   SIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLP 68
           +I + +D + P   GV T I  +   L + GH V + T    N    R    G +V+ LP
Sbjct: 2   NIGIFTDTYSPQISGVATSIMIMENELRKQGHTVYIFTTTDPNAD--RESEEG-RVFRLP 58

Query: 69  FIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLR----- 123
            I           +  M    K++ R N+ IIH H+ FS          GL+G R     
Sbjct: 59  SIPFVFFPERRVAIAGMNKFIKLVGRLNLDIIHTHTEFSL---------GLLGKRIAKKY 109

Query: 124 ---TVFTDHSLFGFADASAILTNKLVLQYSLI-NVDQTICVSYTS--KENTVLRGKLDPN 177
              ++ T H++  + D    +    +L  S++  + ++ C SY +       +R  L+  
Sbjct: 110 NIPSIHTYHTM--YVDYLHYIAKGKILTPSMVGKMTKSFCDSYDAIITPTAKVRHHLEEQ 167

Query: 178 KVS----TIPNAIETSLFTPDRNQFF----------NNPTTIVFLGRLVYRKGADLLCEI 223
            +     T+P   + S F P   Q             N + I+ LGR+ + K  D +   
Sbjct: 168 GIHKLMYTVPTGTDISSFAPVEKQRILDLKQSLGIEENDSVILSLGRIAHEKNIDAIINA 227

Query: 224 VPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFI 283
           +P+V     + + +I GDGP R +LE+++E  +L   V+  G +    +      G +F+
Sbjct: 228 MPEVLETKPNAKLVIVGDGPVRKDLEKLVETKQLENHVIFTGAVDWENISLYYQLGDLFV 287

Query: 284 NTSLTEAFCMSIVEAASCGLHVVSTR 309
           + S TE   ++  EA +  L VV+ R
Sbjct: 288 SASTTETQGLTYAEAMAASLPVVAKR 313
>ref|NP_466078.1| (NC_003210) weakly similar to human
           N-acetylglucosaminyl-phosphatidylinositol biosynthetic
           protein [Listeria monocytogenes EGD-e]
 emb|CAD00633.1| (AL591983) weakly similar to human
           N-acetylglucosaminyl-phosphatidylinositol biosynthetic
           protein [Listeria monocytogenes]
          Length = 427

 Score = 83.2 bits (203), Expect = 8e-15
 Identities = 80/326 (24%), Positives = 139/326 (42%), Gaps = 39/326 (11%)

Query: 9   SIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLP 68
           +I + +D + P   GV T I  +   L + GH V + T    N    R    G +V+ LP
Sbjct: 2   NIGIFTDTYSPQISGVATSIMIMENELRKQGHTVYIFTTTDPNAD--RESEEG-RVFRLP 58

Query: 69  FIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLR----- 123
            I           +  M    K++ R ++ IIH H+ FS          GL+G R     
Sbjct: 59  SIPFVFFPERRVAIAGMNKFIKLVGRLDLDIIHTHTEFSL---------GLLGKRIAKKY 109

Query: 124 ---TVFTDHSLFGFADASAILTNKLVLQYSLI-NVDQTICVSYTS--KENTVLRGKLDPN 177
              ++ T H++  + D    +    +L  S++  + ++ C SY +       +R  L+  
Sbjct: 110 HIPSIHTYHTM--YVDYLHYIAKGKILTPSMVGKMTKSFCDSYDAIITPTAKVRHHLEEQ 167

Query: 178 KVS----TIPNAIETSLFTPDRNQFF----------NNPTTIVFLGRLVYRKGADLLCEI 223
            +     T+P   + S F P   Q             N   I+ LGR+ + K  D +   
Sbjct: 168 GIHKLMYTVPTGTDISSFAPVEKQRILDLKKLLGIGENDPVILSLGRIAHEKNIDAIINA 227

Query: 224 VPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFI 283
           +P+V     + + +I GDGP R +LE+++E  +L + V+  G +    +      G +F+
Sbjct: 228 MPEVLQTKTTAKLVIVGDGPVRKDLEKLVEEKQLADHVIFTGAVDWENISLYYQLGDLFV 287

Query: 284 NTSLTEAFCMSIVEAASCGLHVVSTR 309
           + S TE   ++  EA +  L VV+ R
Sbjct: 288 SASTTETQGLTYAEAMAASLPVVAKR 313
>ref|NP_440248.1| (NC_000911) unknown protein [Synechocystis sp. PCC 6803]
 pir||S74777 hypothetical protein slr1076 - Synechocystis sp. (strain PCC 6803)
 dbj|BAA16928.1| (D90901) ORF_ID:slr1076~unknown protein [Synechocystis sp. PCC
           6803]
          Length = 381

 Score = 80.9 bits (197), Expect = 4e-14
 Identities = 66/250 (26%), Positives = 112/250 (44%), Gaps = 30/250 (12%)

Query: 99  IIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASAILTNKLVLQYSLINVDQTI 158
           II GH+ F+ +AH   ++  LMG+      H +  +      L N  ++Q +L + D+ +
Sbjct: 94  IICGHANFTPVAH---LVQRLMGISYWTVAHGVDAWN-----LQNPHIIQ-ALRHADRIL 144

Query: 159 CVSYTSKENTVLRGKLDPNKVSTIPNAIETSLF---------------TPDRNQFFNNPT 203
            VS+ +++  +    LDP KV  +PN  +TS F               TPD+        
Sbjct: 145 AVSHYTRDRLLQEQALDPEKVVVLPNTFDTSRFQIAPKPQSLLEKYNLTPDQQVIL---- 200

Query: 204 TIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVI 263
           TI  L      KG D +   +P++     ++ ++IGG G  R  +E++++   L + V +
Sbjct: 201 TIARLAGEERYKGYDQIIRALPEIIKTIPNIHYLIGGKGGDRPRIEKLIQDLDLEDYVTL 260

Query: 264 LGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFI 323
            G +P  ++    N   +F   S  E F +  +EA +CG   +     G  + L  GE  
Sbjct: 261 AGFIPDEELADHYNLCDVFAMPSKGEGFGIVYLEAMACGKPTIGGNQDGAIDALCNGELG 320

Query: 324 SLEEPVPDDL 333
            L    PDDL
Sbjct: 321 VLVN--PDDL 328
>ref|NP_228431.1| (NC_000853) lipopolysaccharide biosynthesis protein, putative
           [Thermotoga maritima]
 pir||E72354 probable hexosyltransferase (EC 2.4.1.-) TM0622 - Thermotoga
           maritima (strain MSB8)
 gb|AAD35706.1|AE001736_4 (AE001736) lipopolysaccharide biosynthesis protein, putative
           [Thermotoga maritima]
          Length = 388

 Score = 79.7 bits (194), Expect = 1e-13
 Identities = 67/229 (29%), Positives = 114/229 (49%), Gaps = 15/229 (6%)

Query: 173 KLDPNKVST--IPNAIETSLFTPDRNQFFNNPTTIVF-LGRLVYRKGADLLCEIVPKVCA 229
           KL   K+ST  I N I+   F+ D+ +  +   TI+  + RL   K   LL     K   
Sbjct: 164 KLYGRKISTPVIYNGIDVQKFSIDQPKRVDRDKTILINVARLSREKNHALLVRAFSKAVQ 223

Query: 230 RHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTE 289
              ++   + GDG  R ++EE++++  L E+V   G+   + V  +L+Q  IF+ +S  E
Sbjct: 224 SCPNLELWLVGDGELRRDIEELVKQLGLEEKVKFFGV--RSDVPELLSQADIFVLSSDYE 281

Query: 290 AFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAV-----DRR 344
            F + + EA + GL V++T +GG+PE+L  G    L   VP   VDAL KA+     D +
Sbjct: 282 GFGLVVAEAMAAGLPVIATAIGGIPEILEGGRAGIL---VPPKDVDALAKAIVELARDEK 338

Query: 345 EKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQKAVESEPTGRLGRLKG 393
           ++  L D   K   V++ ++        + +Y + +E +   +  R+KG
Sbjct: 339 KRAELSDYGRK--LVAERFDIRRTVREYEKLYLELLEKKKGSKKFRIKG 385
>gb|AAL80915.1| (AE010196) hypothetical protein [Pyrococcus furiosus DSM 3638]
          Length = 389

 Score = 78.2 bits (190), Expect = 3e-13
 Identities = 53/213 (24%), Positives = 100/213 (46%), Gaps = 15/213 (7%)

Query: 174 LDPNKVSTIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYR--------KGADLLCEIVP 225
           + P+K+  IPN  + + F P   +       +V   +++          KG + L     
Sbjct: 179 ITPSKIRYIPNGFDGNKFYPIPQEIARRKLNLVEYEKIIINVANMYSRVKGHEYLLRAFS 238

Query: 226 KVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINT 285
           KV         I+ G G     L+++ +   L  RV+  G  PH+++   +N   +F+  
Sbjct: 239 KVAENTSDAFLILVGSGKLLSHLKKLADNLYLGHRVLFAGSKPHDEIPLWMNAADLFVLP 298

Query: 286 SLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPV-PDDLVDALLKAVDRR 344
           SL E+F +  +EA +CG+ VV+TR GG  E++   ++  L EP  P +L + +L A+++ 
Sbjct: 299 SLRESFGVVQIEAMACGVPVVATRNGGSEEIIISEDYGLLCEPANPKELAEKILIALEKE 358

Query: 345 EKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQ 377
                    EK    ++ + W ++A +T  +Y+
Sbjct: 359 WD------REKIRKYAEQFTWENIAKKTLEVYR 385
>dbj|BAB18471.1| (AB033991) BtrM [Bacillus circulans]
          Length = 389

 Score = 77.4 bits (188), Expect = 4e-13
 Identities = 40/125 (32%), Positives = 69/125 (55%)

Query: 204 TIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVI 263
           T++FLGR+ + KG      +  ++  +   ++FI+ GDGP+R  +EE ++   L  +  I
Sbjct: 207 TVLFLGRIAHEKGWSTFVSVAKELADKIGDLQFIVCGDGPQREAMEEQIKAANLQNQFRI 266

Query: 264 LGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFI 323
            G + H  V   L+  Q+F+  S  E F  S++EAA  G+ ++ST  GG  ++   GE  
Sbjct: 267 TGFISHKFVSCYLHHAQLFLLPSHHEEFGGSLIEAAIAGVPIISTNNGGPADIFTHGETA 326

Query: 324 SLEEP 328
            L++P
Sbjct: 327 ILKDP 331
>ref|NP_213400.1| (NC_000918) hypothetical protein [Aquifex aeolicus]
 pir||D70351 probable hexosyltransferase (EC 2.4.1.-) aq_572 [similarity] -
           Aquifex aeolicus
 gb|AAC06809.1| (AE000696) hypothetical protein [Aquifex aeolicus]
          Length = 366

 Score = 77.4 bits (188), Expect = 5e-13
 Identities = 86/324 (26%), Positives = 142/324 (43%), Gaps = 21/324 (6%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPF 69
           IAL +D F  + GG       LA  L + G+ V+VIT      +         KV  LP 
Sbjct: 3   IALFTDSFRKDLGGGTQVARQLAFGLSKKGYEVLVITGSTAEEE------TPFKVLKLPS 56

Query: 70  IVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDH 129
           I  Y       I      L K L   N  +IH H  F +     L++G ++ + TV T H
Sbjct: 57  I-KYPFYHNVEIALPNVELLKELKNFNPDVIHYHDPFLA-GTMALLMGKILKIPTVGTIH 114

Query: 130 ------SLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIP 183
                 +  G    + ++  KLV  +     + T CV + SK    L  +LD   V  I 
Sbjct: 115 IHPKQLTYHGIKIDNGVIAKKLVSFFG----NFTDCVVFVSKYQKKLYEELDSFCVKVIY 170

Query: 184 NAIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGP 243
           N I    F  ++ +  N    I+ + RL   K  +   + V ++ ++   V + I G+G 
Sbjct: 171 NGIPDYFFVSEKRKLRNPRNRILTVSRLDKDKNPEFALKCVAEI-SKEVPVEYTIVGEGN 229

Query: 244 KRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGL 303
           ++ +LE++    KL  +   LG +P  ++  +     + +NTS TE F +S  EA + G+
Sbjct: 230 EKEKLEKLAR--KLGIKANFLGFVPREELPELYLSHDVLLNTSKTETFGLSFAEAMATGM 287

Query: 304 HVVSTRVGGVPEVLPIGEFISLEE 327
            V++ + G  PE++  G  +  E+
Sbjct: 288 PVIALKEGSAPEIVGDGGILCEEK 311
>emb|CAB50741.1| (AJ243803) putative glycosyl transferase [Streptomyces coelicolor
           A3(2)]
 emb|CAB61928.1| (AL133278) putative glycosyl transferase [Streptomyces coelicolor
           A3(2)]
          Length = 387

 Score = 77.0 bits (187), Expect = 6e-13
 Identities = 103/404 (25%), Positives = 175/404 (42%), Gaps = 53/404 (13%)

Query: 10  IALVSDFFCPNA-GGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLP 68
           + L+S  F P+  GG   H+ FLA+   EL   V +  H +G  +     ++G+ + + P
Sbjct: 3   VGLLSREFPPDVYGGAGVHVEFLAR---ELARLVDLDVHSWGEGR-----TDGV-LRHRP 53

Query: 69  FIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTD 128
           +  A +GA       S+       L E  +++H H+ +++L      +  L G+  V T 
Sbjct: 54  W-SALDGANDALRTFSVDLAMTAAL-EGRELVHSHTWYANLGGHLAKL--LHGVPHVVTA 109

Query: 129 HSLFGFADASAILTNKLVLQYSLIN---------VDQTICVSYTSKENTV-LRGKLDPNK 178
           HSL       A    +L   Y L            D  I VS   +E+ +     LD ++
Sbjct: 110 HSLEPLRPWKA---EQLGGGYELSGWAERTAFEAADAVIAVSGAMREDILGCYPDLDASR 166

Query: 179 VSTIPNAIETSLFTP-------DRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARH 231
           V  + N I+T L+ P       DR     +   ++F+GR+  +KG   L   V  +    
Sbjct: 167 VHVVHNGIDTRLYRPDHGTDVLDRVGLDRSRPYVLFVGRITRQKGVPQLLRAVRDI---D 223

Query: 232 KSVRFIIGGDGPKRIEL-EEMLERFKLHERVV-----ILGMLPHNQVKRVLNQGQIFINT 285
            + + ++    P   E+ +E  + F    R       I  MLP  +V ++L    +F+  
Sbjct: 224 PAAQVVLCAGAPDTPEIDQEFRDLFAGLSRAREGVHWIPRMLPRTEVIQLLTHAAVFVCP 283

Query: 286 SLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRRE 345
           S+ E   +  +EA +CG  VV++RVGG+PEV+  G    +  P  D   DA    + R  
Sbjct: 284 SVYEPLGIVNLEAMACGTPVVASRVGGIPEVVTDG-VTGVLVPREDGADDAFEAGLARAL 342

Query: 346 KGLLMDP--------TEKHEAVSKMYNWPDVAARTQVIYQKAVE 381
             +L DP          +  AV + + W  VA RT  +Y++ ++
Sbjct: 343 DSVLGDPAGARRMGEAGRARAVEE-FGWDAVARRTVRLYEEILK 385
>ref|NP_248617.1| (NC_000909) LPS biosynthesis protein, putative [Methanococcus
           jannaschii]
 pir||F64500 probable hexosyltransferase (EC 2.4.1.-) MJ1607 - Methanococcus
           jannaschii
 gb|AAB99629.1| (U67601) LPS biosynthesis protein, putative [Methanococcus
           jannaschii]
          Length = 390

 Score = 75.4 bits (183), Expect = 2e-12
 Identities = 66/241 (27%), Positives = 117/241 (48%), Gaps = 20/241 (8%)

Query: 156 QTICVSYTSKENTVLRGKLDPNKVSTIPNAI-----ETSLFTPDRNQFF------NNPTT 204
           Q I VS + KE          +KV  I N I     + +L   ++  F       ++   
Sbjct: 151 QVITVSKSLKEEVCSIFNTPEDKVKVIYNGINPWEFDINLSWEEKINFRRSIGVQDDEKM 210

Query: 205 IVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVIL 264
           I+F+GRL Y+KG + L   +PK+  RH + + +I G G  R  LE++  +  +  +VV L
Sbjct: 211 ILFVGRLTYQKGIEYLIRAMPKILERHNA-KLVIAGSGDMRDYLEDLCYQLGVRHKVVFL 269

Query: 265 GMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIG-EFI 323
           G +  + +K++     + +  S+ E F +  +EA + G  VV + VGG+ E++      I
Sbjct: 270 GFVNGDTLKKLYKSADVVVIPSVYEPFGIVALEAMAAGTPVVVSSVGGLMEIIKHEVNGI 329

Query: 324 SLEEPVPDDL---VDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQKAV 380
            +    PD +   VD +L     RE   +++  +K   V + Y+W ++A  T  +Y+ A+
Sbjct: 330 WVYPKNPDSIAWGVDRVLSDWGFRE--YIVNNAKKD--VYEKYSWDNIAKETVNVYKIAM 385

Query: 381 E 381
           E
Sbjct: 386 E 386
>ref|NP_242281.1| (NC_002570) BH1415~unknown conserved protein in others [Bacillus
           halodurans]
 dbj|BAB05134.1| (AP001512) BH1415~unknown conserved protein in others [Bacillus
           halodurans]
          Length = 923

 Score = 72.7 bits (176), Expect = 1e-11
 Identities = 94/403 (23%), Positives = 179/403 (44%), Gaps = 42/403 (10%)

Query: 6   GPYSIALVSDFFCPN-AGGVETHIYFLAQCLIELGHRVVVITHGYG-----NRKGIRYLS 59
           G  SI ++S  + P+  GG+  H+  L+Q L + GH + V+T          + G  ++ 
Sbjct: 535 GTCSILMLSWEYPPHVVGGLSRHVDALSQALAKKGHEIHVVTAAMDGAPEYEKNGEVHIH 594

Query: 60  --NGLKVYYLPFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSL-AHETLMI 116
             +GL+    PF+           V S+     + + E+V+ ++    F  + AH+ L+ 
Sbjct: 595 RVSGLQPEREPFL---------DWVASL----NLAMFEHVKKLYRFRPFDVIHAHDWLVS 641

Query: 117 GGLMGLRTVFTDHSLFGFADASAILTNKLV---LQYSL--------INVDQTICVSYTSK 165
           G  + L+ +F   SL     A+    N+ +   LQ ++           DQ I  S   K
Sbjct: 642 GAALALKHLFQT-SLMATIHATEHGRNQGIHTELQQAIHEQEMKLVTEADQIIVCSQFMK 700

Query: 166 ENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQFFN--NPTTIVFLGRLVYRKGADLLCEI 223
           E+       +P+KV+ I N +        R Q  +  N   +  +GR+V  KG  LL E 
Sbjct: 701 EHVQSLFVPNPDKVAVIANGVAREQIEAARLQTISPENRFIVFSVGRIVQEKGFSLLIEA 760

Query: 224 VPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFI 283
             K     + ++F++ G GP   + ++ ++   L   +  +G +  ++     ++  + I
Sbjct: 761 AAKCKELGEPIQFVVAGHGPLLADYQQQVKERHLEAWISFVGYISDSERNEWYHRADVCI 820

Query: 284 NTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALL-KAVD 342
             SL E F +  +EA + G   + +  GG+ E++  G+   L+ P  D  VDA++ + + 
Sbjct: 821 FPSLYEPFGIVALEAMAAGTPTIVSDTGGLAEIVEHGDN-GLKVPTGD--VDAIVAQLLS 877

Query: 343 RREKGLLMDPT--EKHEAVSKMYNWPDVAARTQVIYQKAVESE 383
              K LL      +  + V + Y+W  +A +T+ I  K ++ +
Sbjct: 878 LYHKPLLRAQIGFKGSQDVIEQYSWETIADQTEAILVKKMKRD 920
>ref|NP_378386.1| (NC_003106) 352aa long conserved hypothetical protein [Sulfolobus
           tokodaii]
 dbj|BAB67495.1| (AP000989) 352aa long conserved hypothetical protein [Sulfolobus
           tokodaii]
          Length = 352

 Score = 71.1 bits (172), Expect = 3e-11
 Identities = 51/175 (29%), Positives = 90/175 (51%), Gaps = 10/175 (5%)

Query: 147 LQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQFFNNPTTIV 206
           L+ ++ N    I VS T+K   + R ++D +K++ I N I+  ++ P          T++
Sbjct: 126 LEKTIRNYPYIISVSNTTKYELIKRFRIDESKITVIYNGIDHEIYKPGEKSPI---PTVL 182

Query: 207 FLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLER-FKLHERVVILG 265
           ++GRL   K      +I  KV   +K++ +I GG      +LEE ++R     + ++ LG
Sbjct: 183 WIGRLKNYKNPLDAVKIFKKV-KNNKAIFYIAGGG-----DLEENVKRVISGQKNIIFLG 236

Query: 266 MLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIG 320
            +  +Q  ++  Q    I+TS  E + M+IVEA SCG   V+   G +PE++  G
Sbjct: 237 KVNESQKIKLYQQAWAVISTSFIEGWGMTIVEANSCGTPAVAYSTGSIPEIIEDG 291
 Score = 35.3 bits (80), Expect = 2.2
 Identities = 22/95 (23%), Positives = 48/95 (50%), Gaps = 8/95 (8%)

Query: 15  DFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGN----RKGIRYLSNG----LKVYY 66
           D F P AGG E  IY +++ L++ G  +  ++   GN      GI++L  G    L ++ 
Sbjct: 10  DIFHPQAGGAERVIYEVSRRLVKKGFDITWLSEDVGNFNDELDGIKFLHAGNKYTLHLHS 69

Query: 67  LPFIVAYNGATLGSIVGSMPWLRKVLLRENVQIIH 101
           L +        + S+  ++P+   ++ ++++ ++H
Sbjct: 70  LSYAKRGYDVVIDSVAHAVPFFSYIVNKKSIALVH 104
>ref|NP_489275.1| (NC_003272) probable glycosyl transferase [Nostoc sp. PCC 7120]
 dbj|BAB76934.1| (AP003599) ORF_ID:alr5235~probable glycosyl transferase [Nostoc sp.
           PCC 7120]
          Length = 348

 Score = 71.1 bits (172), Expect = 3e-11
 Identities = 48/139 (34%), Positives = 73/139 (51%), Gaps = 7/139 (5%)

Query: 182 IPNAIETSLF--TPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIG 239
           IPN     LF   P+ N+       IVFLGRLV  KG D+L E +  +     S    I 
Sbjct: 153 IPNPYRDYLFRIIPEANR----NKEIVFLGRLVSEKGVDILLESLASLAEYRLSPLLTIV 208

Query: 240 GDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSL-TEAFCMSIVEA 298
           GDGP++ +LE   ++  +H+RVV +G     ++  +LN+ QI +  SL  E F +  +E 
Sbjct: 209 GDGPEKAKLELKSKKLGIHQRVVFVGSKVGEELVSLLNEHQIMVIPSLYDEPFGVVALEG 268

Query: 299 ASCGLHVVSTRVGGVPEVL 317
            +CG  VV +  GG+ + +
Sbjct: 269 IACGCVVVGSEGGGLKDAI 287
 Score = 41.5 bits (96), Expect = 0.028
 Identities = 26/66 (39%), Positives = 37/66 (55%), Gaps = 7/66 (10%)

Query: 9  SIALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLP 68
          +I L+S FF P+ GG ET+   LA+   ++GH+V+V+T   GN       +NGL     P
Sbjct: 2  NILLLSMFFYPSLGGSETNAEILARQFSQMGHKVIVVTQTIGNNLD----ANGLP---FP 54

Query: 69 FIVAYN 74
          F V  N
Sbjct: 55 FEVIRN 60
>ref|NP_275513.1| (NC_000916) LPS biosynthesis RfbU related protein
           [Methanothermobacter thermautotrophicus]
 pir||H69147 LPS biosynthesis RfbU related protein - Methanobacterium
           thermoautotrophicum (strain Delta H)
 gb|AAB84876.1| (AE000822) LPS biosynthesis RfbU related protein
           [Methanothermobacter thermautotrophicus]
          Length = 395

 Score = 70.4 bits (170), Expect = 6e-11
 Identities = 93/356 (26%), Positives = 153/356 (42%), Gaps = 33/356 (9%)

Query: 13  VSDFFCPN--AGGVETHIYFLAQCLIELGHRVVV-ITHGYGNRKGI---RYLS-NGLKVY 65
           V+ +F P+  AGG    +Y LA   +  GH V V  T G+  R  +   R L  +G++ Y
Sbjct: 18  VTPYFKPSWEAGGPPRSVYDLASRQVSAGHEVTVYTTDGFKRRLDVEVNRPLDVDGIRTY 77

Query: 66  YLPFIVAYNGATLGSIVG-SMPWLRKVLLRE-NVQIIHGHSTFSSLAHETLMIGGLMGLR 123
           Y   +  Y    +   V   +P++    +RE +V  IH H TF  LA     +    G+ 
Sbjct: 78  YFRNLSMYLAGNMNLPVPLKLPYVAWREIREFDVVHIHEHRTF--LAAVVATLASRAGVP 135

Query: 124 TVFTDH-SLFGFADASA------ILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDP 176
            +   H S+   + A+       I  N+++   S I    T+   +  K    +  KLD 
Sbjct: 136 YIVQPHGSVPTMSRATLKEVFDFIAGNRIMYGASRIVATSTVESGFYRK----VYPKLDA 191

Query: 177 NKVSTIPNAIETSLFTPDRNQF-----FNNPTTIVFLGRLVYRKGADLLCEIVPKVCARH 231
             +  +PN ++     P R  F       +   I++LGR+  RKG D+L      +    
Sbjct: 192 EAIVKVPNPVDIP-HRPSRGLFRKKWGLEDARIILYLGRIHERKGLDILLRAFRDM--DE 248

Query: 232 KSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFI--NTSLTE 289
            +V  I G D      L  +++   + ERV++ G L             +F+  + S  E
Sbjct: 249 DTVLVITGPDDHYLERLMGLIDELGIGERVLLTGPLYEMDKLEAYVDADVFVLPSASKYE 308

Query: 290 AFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRRE 345
           +F  S  EA +CG  VV T   G+ E +  G+ I +  P   DL DA+++ +  R+
Sbjct: 309 SFGNSAAEAIACGTPVVVTSSCGISEWMDPGDGI-IARPSARDLRDAIIRVLKERD 363
>ref|NP_248171.1| (NC_000909) conserved hypothetical protein [Methanococcus
           jannaschii]
 pir||H64446 probable hexosyltransferase (EC 2.4.1.-) MJ1178 [similarity] -
           Methanococcus jannaschii
 gb|AAB99181.1| (U67559) conserved hypothetical protein [Methanococcus jannaschii]
          Length = 351

 Score = 69.6 bits (168), Expect = 1e-10
 Identities = 79/375 (21%), Positives = 162/375 (43%), Gaps = 41/375 (10%)

Query: 12  LVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIV 71
           L+   + P  GG+  H+  L + L ++   ++     Y + +   Y    + ++ +P + 
Sbjct: 7   LMPSIYYPYIGGITLHVENLVKRLKDIEFHILT----YDSYEENEY--KNVIIHNVPHLK 60

Query: 72  AYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSL 131
            + G  +  ++ +    + ++  E + +IH H  F         +G L+    +   H L
Sbjct: 61  KFRG--ISYLINAYKIGKNIIESEGIDLIHSHYAFPQGC-----VGALLK-NKLSIPHIL 112

Query: 132 FGFADASAILTNKL----VLQYSLINVDQTICVSYTSKENTVLRGKLD---PNKVSTIPN 184
                 + IL N +      +Y+  N D+ ICVS        ++ +LD    N+   I N
Sbjct: 113 TLHGSDALILKNSIKGRYFFKYATTNSDKIICVS------KYIKNQLDENLKNRAIVIYN 166

Query: 185 AIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPK 244
            +   +   + +  F      +F+G  V +KG D+L + +  +        F + GDG  
Sbjct: 167 GVNKEILYNEGDYNFG-----LFVGAFVPQKGVDILIDAIKDI-----DFNFKLIGDGKL 216

Query: 245 RIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLH 304
             ++E  + +  L   + +LG    ++V   + +    +  S +E F M  VE  +C   
Sbjct: 217 YKKIENFVVKNNL-SHIELLGRKSFDEVASFMRKCSFLVVPSRSEGFGMVAVEGMACSKP 275

Query: 305 VVSTRVGGVPEVLPIG-EFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMY 363
           V++TRVGG+ E++  G   +  E+  P+DL + +L+ ++  E  L     E  +  SK +
Sbjct: 276 VIATRVGGLGEIVIDGYNGLLAEKNNPNDLKEKILELINNEE--LRKTLGENGKEFSKKF 333

Query: 364 NWPDVAARTQVIYQK 378
           +W       + +Y++
Sbjct: 334 SWEKCVMGVRKVYEE 348
>ref|NP_489278.1| (NC_003272) glycosyltransferase [Nostoc sp. PCC 7120]
 dbj|BAB76937.1| (AP003599) glycosyltransferase [Nostoc sp. PCC 7120]
          Length = 382

 Score = 69.2 bits (167), Expect = 1e-10
 Identities = 75/321 (23%), Positives = 137/321 (42%), Gaps = 28/321 (8%)

Query: 22  GGVETHIYFLAQCLIEL---GHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIVAYNGATL 78
           GG++T+  FL Q +  +    +  V + H    R    + +  +  ++   IV     T 
Sbjct: 18  GGIQTYSAFLLQAIQNIYPDANYGVFLMH--DRRSSANFTNKNITQFHCAGIVPLVLRTP 75

Query: 79  GSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADAS 138
                 M W   V  R N+ +I  H  F+ +A++     G+    T+      +   +A 
Sbjct: 76  LFATQLMAW--GVTQRPNL-VIASHLNFTVIANKLNRFAGI-PYWTIAHGVEAWDLKNAE 131

Query: 139 AILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTP----- 193
                   ++ SL + DQ + VS+ +++  + + +L+P+KVS +PN   +S F P     
Sbjct: 132 --------VKKSLHHADQILAVSHYTRDRIIEKHRLNPDKVSILPNTFASSRFKPAPKPN 183

Query: 194 ---DRNQFFNNPTTIVFLGRLV---YRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIE 247
               + Q       I+ + RL      KG D + + +P +     +V ++I G G  +  
Sbjct: 184 YLLRKYQLKPEQQIILTVARLAEAQRYKGYDQILQALPHIRQLIPNVHYVIVGKGNDKHR 243

Query: 248 LEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVS 307
           +E M+ +  L   V + G +P  Q+    N   +F   S  E F +  +EA +CG  V+ 
Sbjct: 244 IESMIVQQGLQNCVTLAGFVPDEQLCDYYNLCDVFAMPSKREGFGIVYLEALACGKPVLG 303

Query: 308 TRVGGVPEVLPIGEFISLEEP 328
               G  + L  GE  +L +P
Sbjct: 304 GNQDGANDALCHGELGALVDP 324
>ref|NP_127136.1| (NC_000868) LPS BIOSYNTHESIS RFBU RELATED PROTEIN [Pyrococcus
           abyssi]
 pir||A75059 probable hexosyltransferase (EC 2.4.1.-) PAB0973 [similarity] -
           Pyrococcus abyssi (strain Orsay)
 emb|CAB50366.1| (AJ248287) LPS BIOSYNTHESIS RFBU RELATED PROTEIN [Pyrococcus
           abyssi]
          Length = 390

 Score = 68.8 bits (166), Expect = 2e-10
 Identities = 96/397 (24%), Positives = 173/397 (43%), Gaps = 37/397 (9%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSN--GLKVYYL 67
           + +++ +F P  GG+E + Y +A+ L+E G  V VIT    +RKG   L N  G++V  L
Sbjct: 3   LLMITPYFYPEGGGLEKYAYMIARGLVERGWEVKVIT---ASRKG-NSLENLEGIEVIRL 58

Query: 68  -PFIVAYNGATLGSIVGSMPW-LRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMG---- 121
            P  +  N      I  ++P  L KV   E   +I+ H+     A  +  +  ++     
Sbjct: 59  APHFIVSN----TPISFNLPLKLIKVFKEEQFSVINAHTPVPYYADVSAWVNNVLKGSNK 114

Query: 122 ---LRTVFTDHSLFGFA-DASAILTNKLVLQYSLINVDQTICVS-YTSKENTVLRGKLDP 176
              + T   D    GF  D  A L N  + +  L+  D  I  S Y   E+ +LR     
Sbjct: 115 TPFVLTYHNDLVKEGFPLDKVAYLYNLSLQRGLLLLSDTIITPSPYCYYESKLLRRF--K 172

Query: 177 NKVSTIPNAIETSLFTPDR----NQFFNNPTT---IVFLG---RLVYRKGADLLCEIVPK 226
            K+  IP  ++T  + P +    +  +N P +   ++F+G   R    KG   L +    
Sbjct: 173 KKLIWIPPGVDTERYFPGKSYRLHSIYNLPRSAKIVMFIGTMNRGHAHKGVPYLLKAFKY 232

Query: 227 VCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFI--N 284
           V  + K    ++ G G    E ++M     + +RV+  G +  + +        + +  +
Sbjct: 233 VATQVKDSYLVLVGRGDMIPEYKKMCMSLGISKRVIFTGYVEEDILPEFYRSSDVIVLPS 292

Query: 285 TSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPV-PDDLVDALLKAVDR 343
           T++ E F M ++EA + G  V+ T VGG+  V+  G+   L  P  P  L +A++  +  
Sbjct: 293 TTVQEGFGMVLIEAGASGKPVIGTNVGGIKHVIENGKTGILVPPKDPFRLAEAIVTLLTD 352

Query: 344 REKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQKAV 380
                 +  T +   V + Y+W  +  +T++  +  V
Sbjct: 353 DNLARKIGKTGR-RLVEREYSWDKIVEKTEIALKAIV 388
>emb|CAB43611.1| (AJ239004) galactosyl transferase [Streptococcus pneumoniae]
          Length = 354

 Score = 68.8 bits (166), Expect = 2e-10
 Identities = 52/209 (24%), Positives = 101/209 (47%), Gaps = 10/209 (4%)

Query: 178 KVSTIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFI 237
           K+  + N ++TS +   +    +N    +FLGR+  RKGA  L + + +  A + ++   
Sbjct: 152 KIVIVENGVDTSFYVEKKKSITSN--NFLFLGRMGKRKGAYDLIDAMNQAVAINPNLHLT 209

Query: 238 IGGDGPKRIELEEMLER---FKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMS 294
           + GDG    ELE++ ++     L + + I   +     K +    Q  I  S  E   M+
Sbjct: 210 MAGDG----ELEDIRQKISNLNLTDHITIYDWVNQRDKKILFQANQTLILPSYNEGLPMA 265

Query: 295 IVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTE 354
           I+EA + GL ++ST VGG+PE++       ++      L + +L+A    +   LM  + 
Sbjct: 266 ILEAMASGLAIISTPVGGIPEIIHEDNGWLIQPGDISQLSNIILEASYNPDVVSLMG-SN 324

Query: 355 KHEAVSKMYNWPDVAARTQVIYQKAVESE 383
            H+ V + Y++  +  + + IY   +E++
Sbjct: 325 NHKLVEEKYSFHSMHGKIKKIYNTLLETK 353
>gb|AAK20702.1|AF316641_8 (AF316641) WciS [Streptococcus pneumoniae]
          Length = 354

 Score = 68.8 bits (166), Expect = 2e-10
 Identities = 52/209 (24%), Positives = 101/209 (47%), Gaps = 10/209 (4%)

Query: 178 KVSTIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFI 237
           K+  + N ++TS +   +    +N    +FLGR+  RKGA  L + + +  A + ++   
Sbjct: 152 KIVIVENGVDTSFYVEKKKSITSN--NFLFLGRMGKRKGAYDLIDAMNQAVAINPNLHLT 209

Query: 238 IGGDGPKRIELEEMLER---FKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMS 294
           + GDG    ELE++ ++     L + + I   +     K +    Q  I  S  E   M+
Sbjct: 210 MAGDG----ELEDIRQKISNLNLTDHITIYDWVNQRDKKILFQANQTLILPSYNEGLPMA 265

Query: 295 IVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTE 354
           I+EA + GL ++ST VGG+PE++       ++      L + +L+A    +   LM  + 
Sbjct: 266 ILEAMASGLAIISTPVGGIPEIIHEDNGWLIQPGDISQLSNIILEASYNPDVVSLMG-SN 324

Query: 355 KHEAVSKMYNWPDVAARTQVIYQKAVESE 383
            H+ V + Y++  +  + + IY   +E++
Sbjct: 325 NHKLVEEKYSFHSMHGKIKKIYNTLLETK 353
>ref|NP_228433.1| (NC_000853) N-acetylglucosaminyl-phosphatidylinositol
           biosynthesis-related protein [Thermotoga maritima]
 pir||E72352 N-acetylglucosaminyl-phosphatidylinositol biosynthesis-related
           protein - Thermotoga maritima (strain MSB8)
 gb|AAD35708.1|AE001737_1 (AE001737) N-acetylglucosaminyl-phosphatidylinositol
           biosynthesis-related protein [Thermotoga maritima]
          Length = 350

 Score = 68.4 bits (165), Expect = 2e-10
 Identities = 65/246 (26%), Positives = 111/246 (44%), Gaps = 28/246 (11%)

Query: 150 SLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTP-DRNQ-------FFNN 201
           +L N  + I VS    E     G    N  + IPN  +  +F P D+N        +  N
Sbjct: 116 TLENAARCIFVSRALLEKAKSFGYSGQN-ATVIPNGYDPDVFKPMDKNTVRKELGIYKEN 174

Query: 202 PTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERV 261
              + F+G L+  K AD L EI  K+     + RF+I GDG  R   +++L+  K  + V
Sbjct: 175 THYVGFVGNLIPIKRADKLPEIFRKIAKELPNTRFLIVGDGALR---DKILKEMKGLD-V 230

Query: 262 VILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGE 321
           V  G +P  +V + +N   + +  S  E +   I+EA +CG  V+ +  GG+PE +   +
Sbjct: 231 VFAGRVPQVEVAKYMNAMDVMVLPSRNEGWPCVILEAQACGTCVIGSSNGGIPEAIGFEK 290

Query: 322 FI-----SLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIY 376
           ++       EE     +V+ L +  D      LM+        +K + W  V  R   +Y
Sbjct: 291 YVVQEGDKFEERFGKRVVEVLREGYDMNR---LMER-------AKGFTWVKVVERETELY 340

Query: 377 QKAVES 382
           ++ +++
Sbjct: 341 EQIIQA 346
>ref|NP_268794.1| (NC_002737) putative glucosyl transferase [Streptococcus pyogenes]
           [Streptococcus pyogenes M1 GAS]
 gb|AAK33515.1| (AE006509) putative glucosyl transferase [Streptococcus pyogenes M1
           GAS]
          Length = 444

 Score = 68.4 bits (165), Expect = 2e-10
 Identities = 86/368 (23%), Positives = 160/368 (43%), Gaps = 49/368 (13%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNG-LKVYYLP 68
           I L +D + P   GV T I  L + L + GH V + T    +R   R+     +++  +P
Sbjct: 3   IGLFTDTYFPQVSGVATSIRTLKEELEKEGHEVYIFT--TTDRDVKRFEDPTIIRLPSVP 60

Query: 69  FI------VAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGL 122
           F+      V Y G     ++ S     K+    N+ IIH  + F SL     MIG  + +
Sbjct: 61  FVSFTDRRVVYRG-----LISSY----KIAKHYNLDIIHTQTEF-SLGLLGKMIGKALRI 110

Query: 123 RTVFTDHSLFGFADASAILTNKLVLQYSLI---------NVDQTICVSYTSKENTVLRGK 173
             V T H+   + D  + + N  +++ S++         ++D  IC S       +L G 
Sbjct: 111 PVVHTYHT--QYEDYVSYIANGKIIRPSMVKPLLRGYLKDLDGVICPSRIVL--NLLEGY 166

Query: 174 LDPNKVSTIPNAIETSLFTPD---RNQFFN---------NPTTIVFLGRLVYRKGADLLC 221
                   IP  I    +  D     +  N         + T ++ L R+ Y K    + 
Sbjct: 167 EVTIPKRVIPTGIPLEKYIRDDITAEEVTNLKAELGIAGDETMLLSLSRISYEKNIQAII 226

Query: 222 EIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQI 281
             +P + A +  ++ II G+GP   +L+ +  + ++ + V   GM+PH++V         
Sbjct: 227 NQMPAILAENAKIKLIIVGNGPYLQDLKHLAMQLEVDKHVTFTGMVPHDKVALYYKACDF 286

Query: 282 FINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISL---EEPVPDDLVDALL 338
           FI+ S +E   ++ +E+ + G  +++     + +V+    F +L   E  + D ++DA+L
Sbjct: 287 FISASTSETQGLTYIESLASGTPIIAHGNPYLDDVVTDKMFGTLYYAETDLTDAIIDAIL 346

Query: 339 KA--VDRR 344
           K   +D+R
Sbjct: 347 KTPVMDKR 354
>emb|CAB70927.1| (AL137778) putative sugar transferase [Streptomyces coelicolor
           A3(2)]
          Length = 387

 Score = 68.0 bits (164), Expect = 3e-10
 Identities = 98/380 (25%), Positives = 160/380 (41%), Gaps = 34/380 (8%)

Query: 10  IALVSDFFCPNAGGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPF 69
           I +V  +     GGV+ HI  LA+  + LGH V V+     +     Y+ +  +   +P 
Sbjct: 3   IGIVCPYSWDVPGGVQFHIRDLAEYFVRLGHEVSVLAPADDDTPLPPYVVSAGRAVPVP- 61

Query: 70  IVAYNGATLGSIVG--SMPWLRKVLLRENVQIIHGHS-TFSSLAHETLMIGGLMGLRTVF 126
              YNG+      G  S   +R+ L      +IH H  T  SL   T        + T  
Sbjct: 62  ---YNGSVARLNFGFLSAARVRRWLHEGGFDVIHIHEPTSPSLGLLTCWAAQGPIVATFH 118

Query: 127 TDHSLFGFADASAILTNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAI 186
           T +       + A++    +LQ +L  +   I VS  ++   V     D      IPN +
Sbjct: 119 TSN-----PRSRAMIAAYAILQAALEKISARIAVSEYARRTLVEHLGGD---AVVIPNGV 170

Query: 187 ETSLFTPDRNQFFNNPTTIVFLGRLVY-RKGADLLCEIVPKVCARHKSVRFIIGGDGPKR 245
           +   F     +      TI F+GR+   RKG  +L   +P + A     R ++ G G + 
Sbjct: 171 DVDFFADAEPKPEWQGDTIGFIGRIDEPRKGLPVLMRALPAILAARPQTRLLVAGRGDEE 230

Query: 246 IELEEMLERFKLHERVVILGMLPHNQVKRVLNQGQIFI--NTSLTEAFCMSIVEAASCGL 303
             +E + +  +L  RV  LGM+      R L    +++  NT   E+F + +VEA S G 
Sbjct: 231 EAVESLPK--ELRSRVEFLGMISDEDKARFLRSVDLYVAPNTG-GESFGIVLVEAMSAGA 287

Query: 304 HVVSTRVGGVPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPT------EKHE 357
            V+++ +    +VL  G   +  E  P++  DAL +A  R    LL DP       E+  
Sbjct: 288 PVLASDLDAFAQVLDQG---AAGELFPNEDADALAEAAVR----LLADPERRAALRERGS 340

Query: 358 AVSKMYNWPDVAARTQVIYQ 377
           A  + ++W  V A    +Y+
Sbjct: 341 AHVRRFDWSTVGADILSVYE 360
>ref|NP_302182.1| (NC_002677) putative transferase [Mycobacterium leprae]
 emb|CAC30668.1| (AL583923) putative transferase [Mycobacterium leprae]
          Length = 438

 Score = 66.9 bits (161), Expect = 7e-10
 Identities = 89/414 (21%), Positives = 162/414 (38%), Gaps = 72/414 (17%)

Query: 22  GGVETHIYFLAQCLIELGHRVVVI----------THGYGNR--KGIRYL----------- 58
           GG+  H++ L+  L   GH VVV+          TH   +   +G+R +           
Sbjct: 40  GGLGRHVHHLSTALAAAGHDVVVLSRRPSGTDPCTHPTSDEISEGVRVIAAAQDPHEFTF 99

Query: 59  SNGLKVYYLPF--IVAYNGATLGSIVGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMI 116
           SN +  + L     +   G +L      +PW           ++H H     +AH  + +
Sbjct: 100 SNDMMAWTLAMGHAMIRTGLSLTRHSSDLPW--------RPDVVHAHDWL--VAHPAITL 149

Query: 117 GGLMGLRTVFTDHSLFGFADASAILTNKLVLQY------------SLINVDQTICVSYTS 164
                +  V T H+       S  ++  L  Q             SLI    ++C     
Sbjct: 150 AQFYDVPMVSTIHATEA-GRHSGWVSGALSRQVHAVESWLVRESDSLITCSASMCNEIIE 208

Query: 165 ------KENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQFFNNPTTIVFLGRLVYRKGAD 218
                  E TV+R  +DP +            F   R +    P  ++++GRL Y KG  
Sbjct: 209 LFGPGLAEITVIRNGIDPARWP----------FAARRAR--TGPAELLYVGRLEYEKGVH 256

Query: 219 LLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLPHNQVKRVLNQ 278
            +   +P++   +      I G+G ++  L +   ++K+ +    +G L HN++   L +
Sbjct: 257 DVIAALPRIRRSYPGTTLTIAGEGTQQDWLVDQARKYKVIKATRFVGHLNHNELLAALQR 316

Query: 279 GQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEPVPDDLVD--A 336
               +  S  E F +  +EAA+ G  +V++ +GG+ E +  G+   +  P P D+ +  A
Sbjct: 317 ADAAVLPSHYEPFGLVALEAAAAGTPLVTSNIGGLGEAVINGQ-TGVSCP-PRDIAELAA 374

Query: 337 LLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIY--QKAVESEPTGRL 388
           ++  V               E ++  ++W  VA +T  +Y   K  E +P  RL
Sbjct: 375 MVCTVLEDPDAAQQRALAARERLTSDFDWQTVAQQTAQVYLAAKRRERQPQPRL 428
>ref|NP_279218.1| (NC_002607) LPS glycosyltransferase; Lpg [Halobacterium sp. NRC-1]
 gb|AAG18698.1| (AE004975) LPS glycosyltransferase; Lpg [Halobacterium sp. NRC-1]
          Length = 333

 Score = 66.1 bits (159), Expect = 1e-09
 Identities = 49/148 (33%), Positives = 72/148 (48%), Gaps = 15/148 (10%)

Query: 178 KVSTIPNA-IETSLFTPDRNQFFNNPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRF 236
           K+ST+P A I+   + P +    +   T+  +GRL   KG D L       CAR      
Sbjct: 136 KISTLPIAGIDVKEYQPSKTHPSHENITVSTVGRLANVKGYDDLIR-----CARD----- 185

Query: 237 IIGGDGPKRIELEEMLERF---KLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCM 293
            IG D   +I  E         K  + V   GM+P+ Q+ + LN   I+   S  E  CM
Sbjct: 186 -IGDDLQFQIAGEGEERERLESKTPDNVNFQGMVPNEQIPQFLNNSDIYFQPSKYEGLCM 244

Query: 294 SIVEAASCGLHVVSTRVGGVPEVLPIGE 321
           +++EA +CGL VV++ VGG+ E +  GE
Sbjct: 245 AVIEAMACGLPVVASDVGGITESVVPGE 272
>gb|AAL25631.1| (AY057452) putative glycosyltransferase [Edwardsiella ictaluri]
          Length = 366

 Score = 66.1 bits (159), Expect = 1e-09
 Identities = 72/349 (20%), Positives = 142/349 (40%), Gaps = 33/349 (9%)

Query: 22  GGVETHIYFLAQCLIELGHRVVVITHGYGNRKGIRYLSNGLKVYYLPFIVAYNGATLGSI 81
           GG E  +  LA      G +V ++         ++  +  +K+Y L         +  S+
Sbjct: 13  GGAEKQLSLLADNFTARGEQVSIVY--LTGEVLVKPKNKNIKIYNLGI-----DKSFSSL 65

Query: 82  VGSMPWLRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASAIL 141
           +  +  L+ ++      +IH H   +++         L   R V + H+           
Sbjct: 66  IKGIWKLKSIISDVRPDVIHSHMYHANILARISCCLSLFSSRLVCSAHN-----KNEGGR 120

Query: 142 TNKLVLQYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQFFN- 200
              ++ + +     +T  VS  + +  + +      K S + N I+ S+F        N 
Sbjct: 121 VRMIIYRMTDFLCAKTTNVSQEALDEFITKKAFRKRKSSLVYNGIDLSIFKKKSTNIQNI 180

Query: 201 --------NPTTIVFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEML 252
                   +   I   GRL   K    L   + K+    K  + II GDGP R ++E ++
Sbjct: 181 KNKLGINFDEKVIFCAGRLTEAKDYPNLILAISKM--HQKKCKIIIAGDGPMRSDIERLI 238

Query: 253 ERFKLHERVVILGMLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGG 312
           +R  L  R++++G++  + +    N   +F+  S  E F + + EA +C   V++T  GG
Sbjct: 239 DRCHLSHRILLIGII--DNISDYYNLSDLFVLPSRWEGFGLVVAEAMACECPVIATDAGG 296

Query: 313 VPEVLPIGEFISLEEPVPDDLVDALLKAVDRREKGLLMDPTEKHEAVSK 361
           V EVL   +++    P+ D       K  ++ ++  L+D +E  +  +K
Sbjct: 297 VAEVLSNADWLV---PIADS-----SKLAEKIDEFFLLDSSEVKDIKAK 337
>ref|NP_349652.1| (NC_003030) Glycosyltransferase [Clostridium acetobutylicum]
 gb|AAK80992.1|AE007802_8 (AE007802) Glycosyltransferase [Clostridium acetobutylicum]
          Length = 352

 Score = 63.0 bits (151), Expect = 1e-08
 Identities = 57/228 (25%), Positives = 106/228 (46%), Gaps = 14/228 (6%)

Query: 88  LRKVLLRENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASAILTNKLVL 147
           ++K+++ +N+ +IH +S   ++    +       L+ V+T H+L         +  KL  
Sbjct: 69  IKKIVISKNINVIHANSLRLAIISSIVKKLYKKDLKIVYTKHNLTILEK----IHTKLFS 124

Query: 148 QYSLINVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPDRNQFFN--NPTTI 205
            +   NVD  + V    ++N +  G +   KV  IPN+I+   F  +     +      +
Sbjct: 125 AFVNKNVDIVLAVCNKDRDNMISIG-VSEEKVKVIPNSIDLKHFKFNSKYLRDAGKDFKV 183

Query: 206 VFLGRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILG 265
             L RL   K  +   +I  K        R +IGGDGP R E+   +E+  L ++V +LG
Sbjct: 184 GMLSRLSKEKNHEFFLDIAEKA-----DFRALIGGDGPLREEINNRIEKSNLKKKVKMLG 238

Query: 266 MLPHNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGV 313
            + ++     L+   + +  S  E F M+++EA + G  V+S  +GG+
Sbjct: 239 NIENSY--EFLSSVDVMLLVSTREIFPMTLLEAMAVGTIVISVDIGGI 284
>ref|NP_279220.1| (NC_002607) LPS biosynthesis protein; Lpb [Halobacterium sp. NRC-1]
 gb|AAG18700.1| (AE004975) LPS biosynthesis protein; Lpb [Halobacterium sp. NRC-1]
          Length = 338

 Score = 61.8 bits (148), Expect = 2e-08
 Identities = 67/289 (23%), Positives = 122/289 (42%), Gaps = 21/289 (7%)

Query: 95  ENVQIIHGHSTFSSLAHETLMIGGLMGLRTVFTDHSLFGFADASAILTN---KLVLQYSL 151
           ++  ++H HS      +   +   L       T+H L+   +A   L +   K V +++ 
Sbjct: 60  DDFDVVHAHSHLYFSTNLAALKRRLGETPLAITNHGLYS-QNAPEWLFDAYLKTVGRWTF 118

Query: 152 INVDQTICVSYTSKENTVLRGKLDPNKVSTIPNAIETSLFTPD---RNQFFNNPTTIVFL 208
              D   C  YT ++   +R     +++  +PN ++T  FTPD    +   ++   ++F+
Sbjct: 119 NQADVVFC--YTDEDRERVREFGVDSRIEVVPNGVDTERFTPDGPTSDLIDHDGPVVLFV 176

Query: 209 GRLVYRKGADLLCEIVPKVCARHKSVRFIIGGDGPKRIELEEMLERFKLHERVVILGMLP 268
           GRLV  K      + V +V A    V+  + GDGP R             E  V LG LP
Sbjct: 177 GRLVEGKRPQDAVKAVSRV-AEDMDVKLYVVGDGPMR-----EELEEMSGEETVFLGQLP 230

Query: 269 HNQVKRVLNQGQIFINTSLTEAFCMSIVEAASCGLHVVSTRVGGVPEVLPIGEFISLEEP 328
           ++++  V   G + +  S  E    +++E  + G+ VV++ +     V+  G   +++  
Sbjct: 231 YDEMPAVYRAGDVLVLPSRAEGLPRTVLEGFASGVPVVASNLEHTKAVIQKGG-QTVDVG 289

Query: 329 VPDDLVDALLKAVDRREKGLLMDPTEKHEAVSKMYNWPDVAARTQVIYQ 377
             D    A+ + +D RE   +         V K + W D A  T  I Q
Sbjct: 290 NVDGYARAIQEVIDDRETRQV-----GRGVVVKTFQWKDTARTTTEILQ 333
CPU time:    71.63 user secs.	    1.47 sys. secs	   73.10 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.323    0.141    0.418 

Gapped
Lambda     K      H
   0.270   0.0470    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 243329920
Number of Sequences: 887402
Number of extensions: 10154301
Number of successful extensions: 23591
Number of sequences better than 10.0: 737
Number of HSP's better than 10.0 without gapping: 312
Number of HSP's successfully gapped in prelim test: 425
Number of HSP's that attempted gapping in prelim test: 22905
Number of HSP's gapped (non-prelim): 843
length of query: 444
length of database: 277,845,442
effective HSP length: 55
effective length of query: 389
effective length of database: 229,038,332
effective search space: 89095911148
effective search space used: 89095911148
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.9 bits)
S2: 74 (33.2 bits)