Sequences with E-value BETTER than threshold (0.002)
gb|AAB81183.1| acyloxyacyl hydrolase [Oryctolagus cuniculus] 1203 0.0
ref|NP_001628.1| acyloxyacyl hydrolase precursor [Homo sapien... 977 0.0
ref|NP_036184.1| acyloxyacyl hydrolase [Mus musculus] >gi|252... 919 0.0
gb|AAM43641.1| ACYLOXYACYL HYDROLASE [Dictyostelium discoideum] 443 e-123
emb|CAC50079.1| GPI inositol deacylase [Trypanosoma brucei br... 338 2e-91
ref|XP_225370.1| similar to acyloxyacyl hydrolase [Mus muscul... 126 1e-27
Sequences with E-value WORSE than threshold
ref|XP_223521.1| similar to prosaposin (variant Gaucher disea... 41 0.10
pir||T00207 P109 protein - silkworm >gi|2575865|dbj|BAA23126.... 40 0.22
gb|AAL92313.1| Proteasome subunit beta type 1 [Dictyostelium ... 38 0.65
sp|P17129|PSPB_CANFA Pulmonary surfactant-associated protein ... 36 2.0
emb|CAB59284.1| NADH dehydrogenase subunit A [Hordeum vulgare] 36 3.2
emb|CAC88101.1| NADH dehydrogenase ND1 subunit [Atropa bellad... 35 4.0
ref|XP_162912.1| hypothetical protein XP_162912 [Mus musculus] 35 6.2
sp|Q61207|SAP_MOUSE Sulfated glycoprotein 1 precursor (SGP-1)... 35 8.3
ref|XP_192668.1| similar to Sulfated glycoprotein 1 precursor... 35 8.3
dbj|BAC40308.1| unnamed protein product [Mus musculus] >gi|26... 35 8.3
ref|NP_035309.1| prosaposin [Mus musculus] >gi|1381582|gb|AAB... 34 9.2
Alignments
>gb|AAB81183.1| acyloxyacyl hydrolase [Oryctolagus cuniculus]
Length = 575
Score = 1203 bits (3080), Expect = 0.0
Identities = 575/575 (100%), Positives = 575/575 (100%)
Query: 1 MKSPWRILVVSPLLLLPLHSSTSRAHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQVHNST 60
MKSPWRILVVSPLLLLPLHSSTSRAHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQVHNST
Sbjct: 1 MKSPWRILVVSPLLLLPLHSSTSRAHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQVHNST 60
Query: 61 VQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQP 120
VQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQP
Sbjct: 61 VQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQP 120
Query: 121 LCHLYPLPKESWKFTLEKARHIVKQSPIMKYTRSGAGICSLPFLAKICQKIKLAIKNSVP 180
LCHLYPLPKESWKFTLEKARHIVKQSPIMKYTRSGAGICSLPFLAKICQKIKLAIKNSVP
Sbjct: 121 LCHLYPLPKESWKFTLEKARHIVKQSPIMKYTRSGAGICSLPFLAKICQKIKLAIKNSVP 180
Query: 181 IKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDG 240
IKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDG
Sbjct: 181 IKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDG 240
Query: 241 IPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQL 300
IPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQL
Sbjct: 241 IPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQL 300
Query: 301 SGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLD 360
SGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLD
Sbjct: 301 SGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLD 360
Query: 361 HPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAH 420
HPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAH
Sbjct: 361 HPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAH 420
Query: 421 GAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQL 480
GAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQL
Sbjct: 421 GAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQL 480
Query: 481 SETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFA 540
SETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFA
Sbjct: 481 SETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFA 540
Query: 541 DQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 575
DQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH
Sbjct: 541 DQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 575
>ref|NP_001628.1| acyloxyacyl hydrolase precursor [Homo sapiens]
sp|P28039|AOAH_HUMAN Acyloxyacyl hydrolase precursor
pir||A40292 acyloxyacyl hydrolase (EC 3.1.1.-), neutrophil precursor
[validated] - human
gb|AAA35506.1| acyloxyacyl hydrolase
gb|AAH25698.1| acyloxyacyl hydrolase (neutrophil) [Homo sapiens]
Length = 575
Score = 977 bits (2500), Expect = 0.0
Identities = 452/576 (78%), Positives = 513/576 (88%), Gaps = 2/576 (0%)
Query: 1 MKSPWRILVVSPLLLLPLHSSTSR-AHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQVHNS 59
M+SPW+IL V+PL LL S++ A+D+Q S+ +TCVGCVLVVSVIEQLAQVHNS
Sbjct: 1 MQSPWKILTVAPLFLLLSLQSSASPANDDQSRPSLSNGHTCVGCVLVVSVIEQLAQVHNS 60
Query: 60 TVQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQ 119
TVQASMERLCSYLPE+ LKT CY+++ FG+DIIKL D+NADVVCHTLEFCKQ GQ
Sbjct: 61 TVQASMERLCSYLPEKLFLKTTCYLVIDKFGSDIIKLLSADMNADVVCHTLEFCKQNTGQ 120
Query: 120 PLCHLYPLPKESWKFTLEKARHIVKQSPIMKYTRSGAGICSLPFLAKICQKIKLAIKNSV 179
PLCHLYPLPKE+WKFTL+KAR IVK+SPI+KY+RSG+ ICSLP LAKICQKIKLA++ SV
Sbjct: 121 PLCHLYPLPKETWKFTLQKARQIVKKSPILKYSRSGSDICSLPVLAKICQKIKLAMEQSV 180
Query: 180 PIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKD 239
P KDVDSDKYS+FPTLRGYHWRGRDCNDSD++VYPGRRP+NWD H+DSNCNGIWGVDPKD
Sbjct: 181 PFKDVDSDKYSVFPTLRGYHWRGRDCNDSDESVYPGRRPNNWDVHQDSNCNGIWGVDPKD 240
Query: 240 GIPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQ 299
G+PYEKKFCEGSQPRGIILLGDSAGAHFHI PEW+T SQMS+NSF+NLPTA+TNELDWPQ
Sbjct: 241 GVPYEKKFCEGSQPRGIILLGDSAGAHFHISPEWITASQMSLNSFINLPTALTNELDWPQ 300
Query: 300 LSGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLL 359
LSG TGFLDS IKE SIYLRL KRN CNHRDYQNIS+NGASSRN+K IESLSRN++L
Sbjct: 301 LSGATGFLDSTVGIKEKSIYLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVL 360
Query: 360 DHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLA 419
D+PAIVIYAMIGNDVC+G K+DPV AMTTPE+LY+NV++ L+ LNSHLP GSHVILYGL
Sbjct: 361 DYPAIVIYAMIGNDVCSG-KSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLP 419
Query: 420 HGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQ 479
G FLWD LH+RYHPLGQLNKD+TY QLYSFL CLQVSPC GWMS+N+TLR LTSERA+Q
Sbjct: 420 DGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTLRTLTSERAEQ 479
Query: 480 LSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLF 539
LS TL+KIAAS+KFTNFNLFY+DFAF E+++EWQK GGQPW+LIE VDGFHPNEVALLL
Sbjct: 480 LSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQPWQLIEPVDGFHPNEVALLLL 539
Query: 540 ADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 575
AD W+KVQ QWP +LGKENPFNPQI++VFGDQGGH
Sbjct: 540 ADHFWKKVQLQWPQILGKENPFNPQIKQVFGDQGGH 575
>ref|NP_036184.1| acyloxyacyl hydrolase [Mus musculus]
gb|AAB81182.1| acyloxyacyl hydrolase [Mus musculus]
dbj|BAC39187.1| unnamed protein product [Mus musculus]
Length = 574
Score = 919 bits (2351), Expect = 0.0
Identities = 424/575 (73%), Positives = 491/575 (84%), Gaps = 1/575 (0%)
Query: 1 MKSPWRILVVSPLLLLPLHSSTSRAHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQVHNST 60
MK PW++ + LLLL HS S ++QPG S +C+GCV++VSVIEQLA+VHNS+
Sbjct: 1 MKFPWKVFKTTLLLLLLSHSLASVPSEDQPGDSYSHGQSCLGCVVLVSVIEQLAEVHNSS 60
Query: 61 VQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQP 120
VQ +MERLCSYLPE+ LKTACY +V FG+DIIKL D+ + ADVVC+ LEFCK+ QP
Sbjct: 61 VQVAMERLCSYLPEKLFLKTACYFLVQTFGSDIIKLLDEAMKADVVCYALEFCKRGAVQP 120
Query: 121 LCHLYPLPKESWKFTLEKARHIVKQSPIMKYTRSGAGICSLPFLAKICQKIKLAIKNSVP 180
CHLYPLP+E+W+ LEKAR ++++S MKY RSG ICSLPFL KICQKI+L+IK +VP
Sbjct: 121 QCHLYPLPQEAWESALEKARQVLRRSSTMKYPRSGRNICSLPFLTKICQKIELSIKKAVP 180
Query: 181 IKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIWGVDPKDG 240
KD+DSDK+S+FPTLRGYHWRGRDCNDSDKTVYPGRRPDNWD H+DSNCNGIWG+DPKDG
Sbjct: 181 FKDIDSDKHSVFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDIHQDSNCNGIWGIDPKDG 240
Query: 241 IPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQMSVNSFLNLPTAVTNELDWPQL 300
IPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLT SQMSVNSFLNLP+A+T+EL+WPQL
Sbjct: 241 IPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTASQMSVNSFLNLPSALTDELNWPQL 300
Query: 301 SGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKNGASSRNVKSLIESLSRNQLLD 360
SG TGFLDS S I+E SIY RLRKRN CNHRDYQ+ISKNGASSRN+K+ IESLSRNQ D
Sbjct: 301 SGVTGFLDSTSGIEEKSIYHRLRKRNHCNHRDYQSISKNGASSRNLKNFIESLSRNQASD 360
Query: 361 HPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNSHLPTGSHVILYGLAH 420
HPAIV+YAMIGNDVCN K D V MTTPEQ+YANV++ L LNSHLP GSHVILYGL
Sbjct: 361 HPAIVLYAMIGNDVCNS-KADTVPEMTTPEQMYANVMQTLTHLNSHLPNGSHVILYGLPD 419
Query: 421 GAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSANETLRALTSERAQQL 480
G FLWD+LH+RYHPLGQLNKDVTY Q +SFL CLQ++PC GWMS+N+TLR LTSERA+QL
Sbjct: 420 GTFLWDSLHNRYHPLGQLNKDVTYAQFFSFLRCLQLNPCNGWMSSNKTLRTLTSERAEQL 479
Query: 481 SETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIEAVDGFHPNEVALLLFA 540
S TL+KIA ++ F NF+LFY+DFAF E++E+WQK GGQPW+LIE VDGFHPNEVA LL A
Sbjct: 480 SNTLKKIATTETFANFDLFYVDFAFHEIIEDWQKRGGQPWQLIEPVDGFHPNEVASLLQA 539
Query: 541 DQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 575
+++WEK+Q QWP VLGKENPFN QIEEVFGDQGGH
Sbjct: 540 NRVWEKIQLQWPHVLGKENPFNSQIEEVFGDQGGH 574
>gb|AAM43641.1| ACYLOXYACYL HYDROLASE [Dictyostelium discoideum]
Length = 564
Score = 443 bits (1129), Expect = e-123
Identities = 220/536 (41%), Positives = 323/536 (60%), Gaps = 26/536 (4%)
Query: 40 CVGCVLVVSVIEQLAQVHNSTVQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDK 99
C C +V+S++ Q + +HN +++ S++ LCS+ P+E + C +V+ +G II FD+
Sbjct: 54 CAACTIVLSLVNQYSGIHNKSIEDSLDELCSFFPDE--AGSLCTWLVNTYGEQIISYFDQ 111
Query: 100 DVNADVVCHTLEFCKQEPGQPLCHLYPLPKESWKFTLEKARHIVKQSPIMKYTRSGAGIC 159
NAD VCH + C P C L FT ++ +Y + +
Sbjct: 112 YQNADDVCHAMNVCT----SPTCRL---------FTSAPSKFYNPDHVHQEYNKEDPKVG 158
Query: 160 SLPFLAKICQKIKLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPD 219
P+ A I + IK+ +PI+D D D +S+ T RGY+WRG+DCND DK+ YPG
Sbjct: 159 GSPW-AWIQELIKVFSSEHLPIQDFDGDHHSLEATFRGYNWRGKDCNDFDKSSYPGTIEG 217
Query: 220 NWDAHRDSNCNGIWGVDPKDGIPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQM 279
DA D NCNGI+GV+ + YE+ FC S G+I+ GDSAGAHF IPP+W+T +
Sbjct: 218 TGDASVDKNCNGIFGVNNQSQ-SYEELFCSNSGAMGVIVSGDSAGAHFSIPPQWMTARDI 276
Query: 280 SVNSFLNLPTAVTNELDWPQLSGTTGFLDSASKIKENSIYLRLRKRNRCNHRDYQNISKN 339
+ ++ + + E+DWP S TG+ SA + +S+YLR+R+RN CNHRDYQN+ N
Sbjct: 277 NSTTYKGMIDILETEVDWPMRSCYTGWDTSAPNV--DSMYLRMRERNLCNHRDYQNLGVN 334
Query: 340 GASSRNVKSLIESLSRNQLLDHPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKM 399
GASS + +++I++++RNQ D P ++ +IGNDVC+G +MTT E+ N+L +
Sbjct: 335 GASSSSTRTIIQTINRNQNTDKPVLLFLELIGNDVCSGHHD--YDSMTTVEEFGENILTI 392
Query: 400 LEALNSHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPC 459
L L + LP GSHV+ GLA G LWD+L +R HPLG TY ++Y FL C+QVSPC
Sbjct: 393 LNYLETTLPKGSHVVFVGLADGRVLWDSLWNRTHPLG-----CTYEEVYDFLNCIQVSPC 447
Query: 460 PGWMSANETLRALTSERAQQLSETLRKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQP 519
GWM+ NET+R TS RA QLS ++ + F NF++ Y DF F + E W GGQ
Sbjct: 448 WGWMNPNETVRDYTSNRAAQLSLVYNQLIKNYTFNNFDMIYYDFPFATINEMWVAQGGQT 507
Query: 520 WELIEAVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 575
++LIE +DGFHPN++A L A + ++ + P+ LG+ N +N QI+ +FG+QGG+
Sbjct: 508 YDLIEPIDGFHPNQIANYLMAGVFYNQIAQDKPEWLGEINQYNTQIQSIFGNQGGY 563
>emb|CAC50079.1| GPI inositol deacylase [Trypanosoma brucei brucei]
Length = 558
Score = 338 bits (859), Expect = 2e-91
Identities = 206/591 (34%), Positives = 321/591 (53%), Gaps = 60/591 (10%)
Query: 5 WRIL---------VVSPLLLLPLHSSTSRAHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQ 55
+++L VV P +H++ + A +++ SD + CV C VV+ + QL Q
Sbjct: 8 YKLLLFTALLQLTVVCP----SIHTAKAEARESK-SLGSSDTWGCVLCTAVVATVSQLGQ 62
Query: 56 VHNSTVQASMERLCSYL--PEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFC 113
+H + ++ CS+ E + KTA +++ GA ++L D+ D VC +++C
Sbjct: 63 LHQIPAKDALGLFCSFFRSAEAVLCKTASLILLE--GA--LQLIDEGRTPDKVCQIMKYC 118
Query: 114 KQEPGQPLCHLYPLPKESWKFTLEKARHIVKQS--PIMKYTRSGAGICSLPFLAKICQKI 171
E C L+P P ++ L K R + ++ R+ +C F
Sbjct: 119 DTEE----CILFP-PDKNDTLPLHKLRSAYRLDGRKLVDACRTFPTLCRPLF-------- 165
Query: 172 KLAIKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNG 231
++S D D D++S +P RG WRGRDC+D D VYPGR ++ D+ RD NCNG
Sbjct: 166 ----EDSA--HDKDGDRFSTYPAKRGTDWRGRDCDDDDARVYPGR--NSTDSQRDENCNG 217
Query: 232 IWGVDPKDGIPYEKKFCEGSQPRGIILLGDSAGAHFHIPPEWLTVSQMSVNSFLNLPTAV 291
I+GV+ YE+ +C S P G+I +GDSA A F IP ++++ +S + N+ +
Sbjct: 218 IYGVEESSKKTYEELWCSNSSPMGVIAVGDSATADFGIPLGYVSILDLSSEAVANIIPVL 277
Query: 292 TNELDWPQLSGTTGFLDSASKIKE-----NSIYLRLRKRNRCNHRDYQNISKNGASSRNV 346
NE+DWP LSG TGF +S + S+Y +L + NRCNHRDYQN+ NGA S ++
Sbjct: 278 DNEIDWPMLSGLTGFANSTRYEPDVDGPMTSVYSKLVELNRCNHRDYQNLGHNGARSGSI 337
Query: 347 KSLIESLSRNQLLD-HPAIVIYAMIGNDVCNGRKTDPVSAMTTPEQLYANVLKMLEALNS 405
S+++S++RN+ PA V ++M+GNDVC + P TP Y ++ + ++ +S
Sbjct: 338 LSILDSVARNRSESVKPAYVFFSMVGNDVCPRPQDAP-----TPLDYYHSLSEAVKKADS 392
Query: 406 HLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVSPCPGWMSA 465
LP GSHV++ L ++ +R HP+G LN DVTY LY +L CLQVSPC GW+++
Sbjct: 393 FLPPGSHVLIVSLVDARAAIGSIVNRIHPIGTLNSDVTYGNLYDYLNCLQVSPCWGWLNS 452
Query: 466 NETLRALTSERAQQLSETL-RKIAASKKFTNFNLFYLDFAFQEVVEEWQKMGGQPWELIE 524
NE++R T ERA ++ + R + S N + L EVV ++ G W+L+
Sbjct: 453 NESVRNETWERASAMNSMISRVVDESTNLENVKVHALGDVIGEVVSSFE---GPLWKLVN 509
Query: 525 AVDGFHPNEVALLLFADQLWEKVQRQWPDVLGKENPFNPQIEEVFGDQGGH 575
VDGFHP+++A L +++ K+Q +L ENPFN I+ FGDQGG+
Sbjct: 510 PVDGFHPSQIATALMGARVFAKMQDL--GILPTENPFNGDIQRRFGDQGGY 558
>ref|XP_225370.1| similar to acyloxyacyl hydrolase [Mus musculus] [Rattus norvegicus]
Length = 212
Score = 126 bits (315), Expect = 1e-27
Identities = 50/59 (84%), Positives = 54/59 (90%)
Query: 175 IKNSVPIKDVDSDKYSIFPTLRGYHWRGRDCNDSDKTVYPGRRPDNWDAHRDSNCNGIW 233
+K +VP KD DSDKYS+FPTLRGYHWRGRDCND DKTVYPGRRPDNWD H+DSNCNGIW
Sbjct: 1 MKKAVPFKDGDSDKYSVFPTLRGYHWRGRDCNDKDKTVYPGRRPDNWDIHQDSNCNGIW 59
>ref|XP_223521.1| similar to prosaposin (variant Gaucher disease and variant
metachromatic leukodystrophy); Prosaposin (sphingolipid
activator protein-1) [Homo sapiens] [Rattus norvegicus]
Length = 527
Score = 40.8 bits (94), Expect = 0.10
Identities = 22/77 (28%), Positives = 44/77 (56%), Gaps = 5/77 (6%)
Query: 39 TCVGCVLVVSVIEQLAQVHNST--VQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKL 96
TC C+ VV +++ + +++ + ++ER+CS +PE V + C +V +G ++++L
Sbjct: 299 TCDVCLNVVQELDKWLETNSTEALISHALERVCSIMPESLVQQ--CITLVDTYGPNLVQL 356
Query: 97 FDKDVNADVVCHTLEFC 113
K V + VC T+ C
Sbjct: 357 VSK-VTPEKVCETIXLC 372
>pir||T00207 P109 protein - silkworm
dbj|BAA23126.1| BmP109 [Bombyx mori]
Length = 965
Score = 39.6 bits (91), Expect = 0.22
Identities = 22/114 (19%), Positives = 55/114 (47%), Gaps = 4/114 (3%)
Query: 10 VSPLLLLPLHSSTSRAHDNQPGTIRSDHYTCVGCVLVVSVIEQLAQVHNS--TVQASMER 67
+ P + P + + + + S+ C C+ V +E + + + S ++ +++
Sbjct: 611 IDPASVCPALQICPQTEEIRRVDVNSEKSNCPLCLFAVEQLESVLKNNRSEENIRKALDG 670
Query: 68 LCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQEPGQPL 121
LC+ L ++ L++ C V + + ++++ D+NA +C L+ C+ + PL
Sbjct: 671 LCTRLSQK--LQSECIDFVDTYSSQLVEMLVADMNAKEICVFLKLCRDQLHDPL 722
Score = 38.0 bits (87), Expect = 0.59
Identities = 23/83 (27%), Positives = 40/83 (47%), Gaps = 5/83 (6%)
Query: 33 IRSDHYTCVGCVLVVSVIEQLAQVH--NSTVQASMERLCSYLPEEWVLKTACYMMVHVFG 90
I+ D C C VV ++++ + + + +E+ C LP ++ CY M+ V+G
Sbjct: 870 IKKDILDCAVCETVVMAVKKVLKNEKLDRNIVHIIEKSCGLLPAKY--NAQCYAMLEVYG 927
Query: 91 ADIIKLFDKDVNADVVCHTLEFC 113
II L + + A VC + FC
Sbjct: 928 ESIIHLIE-EFGAKGVCQRIGFC 949
Score = 37.3 bits (85), Expect = 1.1
Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 16/116 (13%)
Query: 15 LLPLHSSTSRAHDNQPGTI------------RSDHYTCVGCVLVVSVI-EQLAQVHN-ST 60
LLP H S D + I +S CV C V+ I +Q+ HN
Sbjct: 750 LLPKHMLVSEFSDVETNEILDDTVNGRRVSHKSQSNVCVLCEFVLKEIDDQIKDKHNDDE 809
Query: 61 VQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKLFDKDVNADVVCHTLEFCKQE 116
++ ++ +C ++P+ + C V + +I L ++++ VC L+ CK E
Sbjct: 810 IKKAVHGICKHMPKS--VSAECDQFVEKYADLVISLLAQELDPSEVCEELKLCKPE 863
>gb|AAL92313.1| Proteasome subunit beta type 1 [Dictyostelium discoideum]
Length = 200
Score = 38.0 bits (87), Expect = 0.65
Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 4/77 (5%)
Query: 39 TCVGCVLVVSVIEQLAQVH--NSTVQASMERLCSYLPEEWVLKTACYMMVHVFGADIIKL 96
TC C V E L + S + ++ CS LP +W + C ++V+ +G +IKL
Sbjct: 22 TCELCQFSVKAAEDLVTQNFTQSQIIPYLDSACSLLPNQWA--SNCEIIVNTYGLSMIKL 79
Query: 97 FDKDVNADVVCHTLEFC 113
++ +V C L C
Sbjct: 80 VLENETPEVACTQLGLC 96
>sp|P17129|PSPB_CANFA Pulmonary surfactant-associated protein B precursor (SP-B) (6 kDa
protein) (Pulmonary surfactant-associated proteolipid
SPL(Phe)) (Pulmonary surfactant protein 18) (SP 18)
pir||A29072 pulmonary surfactant protein SP 18 precursor - dog (fragment)
gb|AAA30893.1| surfactant protein 18 precursor
Length = 363
Score = 36.5 bits (83), Expect = 2.0
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Query: 31 GTIRSDHYTCVGCVLVVSVIEQLAQ--VHNSTVQASMERLCSYLPEEWVLKTACYMMVHV 88
G R+D C C +V ++ ++ + + V+ +E C LP + +L C+ M+
Sbjct: 54 GNARADDL-CQECQDIVRILTKMTKEAIFQDMVRKFLEHECDVLPLK-LLTPQCHHMLGT 111
Query: 89 FGADIIKLFDKDVNADVVCHTLEFCKQEPGQP 120
+ ++ F +N ++C L CK PG P
Sbjct: 112 YFPVVVDYFQSQINPKIICKHLGLCK--PGLP 141
>emb|CAB59284.1| NADH dehydrogenase subunit A [Hordeum vulgare]
Length = 200
Score = 35.7 bits (81), Expect = 3.2
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%)
Query: 407 LPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVS 457
+P G H +L L+ G FLW + S P+G L + YSFLG L+ +
Sbjct: 42 IPLGYHFVLADLSIGVFLWIAI-SSIAPIGLLMAGYSSNNKYSFLGGLRAA 91
>emb|CAC88101.1| NADH dehydrogenase ND1 subunit [Atropa belladonna]
Length = 363
Score = 35.3 bits (80), Expect = 4.0
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 1/53 (1%)
Query: 405 SHLPTGSHVILYGLAHGAFLWDTLHSRYHPLGQLNKDVTYTQLYSFLGCLQVS 457
S +P G H++L L+ G FLW + S P+G L YSFLG L+ +
Sbjct: 114 SVIPFGDHLVLADLSIGVFLWIAI-SSVAPVGLLMSGYGSNNKYSFLGGLRAA 165
>ref|XP_162912.1| hypothetical protein XP_162912 [Mus musculus]
Length = 206
Score = 34.9 bits (79), Expect = 6.2
Identities = 22/64 (34%), Positives = 27/64 (41%), Gaps = 3/64 (4%)
Query: 15 LLPLHSSTSRAHDNQPGTIRSDH---YTCVGCVLVVSVIEQLAQVHNSTVQASMERLCSY 71
LL H S++ D PG +RS H Y C G S L H ST R+ +
Sbjct: 41 LLQSHGDNSKSDDEGPGAVRSKHSALYWCKGAPFRKSSPAPLCSPHPSTPAVRRSRILAL 100
Query: 72 LPEE 75
LP E
Sbjct: 101 LPRE 104
>sp|Q61207|SAP_MOUSE Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)
Length = 557
Score = 34.5 bits (78), Expect = 8.3
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 40 CVGCVLVVSVIEQLAQVHNSTVQASMERL---CSYLPEEWVLKTACYMMVHVFGADIIKL 96
C C V++ +L V+N+T + ++ L C+ LP+ +T C +V FG ++ +
Sbjct: 317 CQTCQFVMNKFSELI-VNNATEELLVKGLSNACALLPDP--ARTKCQEVVGTFGPSLLDI 373
Query: 97 FDKDVNADVVCHTLEFCKQEP 117
F +VN +C + C P
Sbjct: 374 FIHEVNPSSLCGVIGLCAARP 394
>ref|XP_192668.1| similar to Sulfated glycoprotein 1 precursor (SGP-1) (Prosaposin)
[Mus musculus]
Length = 557
Score = 34.5 bits (78), Expect = 8.3
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 40 CVGCVLVVSVIEQLAQVHNSTVQASMERL---CSYLPEEWVLKTACYMMVHVFGADIIKL 96
C C V++ +L V+N+T + ++ L C+ LP+ +T C +V FG ++ +
Sbjct: 317 CQTCQFVMNKFSELI-VNNATEELLVKGLSNACALLPDP--ARTKCQEVVGTFGPSLLDI 373
Query: 97 FDKDVNADVVCHTLEFCKQEP 117
F +VN +C + C P
Sbjct: 374 FIHEVNPSSLCGVIGLCAARP 394
>dbj|BAC40308.1| unnamed protein product [Mus musculus]
dbj|BAC41035.1| unnamed protein product [Mus musculus]
Length = 554
Score = 34.5 bits (78), Expect = 8.3
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 40 CVGCVLVVSVIEQLAQVHNSTVQASMERL---CSYLPEEWVLKTACYMMVHVFGADIIKL 96
C C V++ +L V+N+T + ++ L C+ LP+ +T C +V FG ++ +
Sbjct: 314 CQTCQFVMNKFSELI-VNNATEELLVKGLSNACALLPDP--ARTKCQEVVGTFGPSLLDI 370
Query: 97 FDKDVNADVVCHTLEFCKQEP 117
F +VN +C + C P
Sbjct: 371 FIHEVNPSSLCGVIGLCAARP 391
>ref|NP_035309.1| prosaposin [Mus musculus]
gb|AAB02695.1| prosaposin [Mus musculus]
Length = 557
Score = 34.1 bits (77), Expect = 9.2
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 40 CVGCVLVVSVIEQLAQVHNSTVQASMERL---CSYLPEEWVLKTACYMMVHVFGADIIKL 96
C C V++ +L V+N+T + ++ L C+ LP+ +T C +V FG ++ +
Sbjct: 317 CQTCQFVMNKFSELI-VNNATEELLVKGLSNACALLPDP--ARTKCQEVVGTFGPSLLDI 373
Query: 97 FDKDVNADVVCHTLEFCKQEP 117
F +VN +C + C P
Sbjct: 374 FIHEVNPSSLCGVIGLCAARP 394
CPU time: 139.10 user secs. 2.51 sys. secs 141.61 total secs.
Database: nr
Posted date: Jan 18, 2003 1:23 PM
Number of letters in database: 421,297,171
Number of sequences in database: 1,315,992
Lambda K H
0.320 0.136 0.430
Gapped
Lambda K H
0.270 0.0470 0.230
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 509294203
Number of Sequences: 1315992
Number of extensions: 22082440
Number of successful extensions: 47709
Number of sequences better than 10.0: 34
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 47669
Number of HSP's gapped (non-prelim): 50
length of query: 575
length of database: 421,297,171
effective HSP length: 55
effective length of query: 520
effective length of database: 348,917,611
effective search space: 181437157720
effective search space used: 181437157720
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.8 bits)
S2: 77 (34.4 bits)