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GPI Anchor Biosynthesis Report: NP_495820.1 (GPI7 family, Caenorhabditis elegans)




BLASTP 2.1.1 [Aug-8-2000]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= 
         (795 letters)

Database: nr
           887,402 sequences; 277,845,442 total letters

Searching..................................................

Results of PSI-Blast iteration 6

Distribution of 60 Blast Hits on the Query Sequence


Sequences with E-value BETTER than threshold (0.002)
Sequences producing significant alignments: (bits) Value
ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis ele... 924 0.0
sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CH... 677 0.0
ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involv... 676 0.0
gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarr... 655 0.0
dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N sh... 600 e-170
gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinosito... 598 e-169
ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class ... 588 e-166
ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; ... 553 e-156
gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melano... 461 e-128
ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan... 409 e-113
pir||T02245 hypothetical protein P1.11659_3 - human >gi|2984587|... 408 e-112
dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [M... 406 e-112
ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans] 371 e-101
ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class ... 362 1e-98
ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]... 348 1e-94
gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melano... 348 2e-94
pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast (... 342 1e-92
ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thalia... 340 5e-92
gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melan... 334 3e-90
ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thalia... 331 3e-89
dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:13516... 321 3e-86
gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melano... 310 5e-83
dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like prote... 290 6e-77
ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like p... 275 1e-72
ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like p... 271 3e-71
gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophos... 265 2e-69
ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like pr... 262 1e-68
pir||T03293 nucleotide pyrophosphatase homolog - rice >gi|818849... 255 2e-66
dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located... 252 2e-65
pir||A39216 plasma cell membrane glycoprotein PC-1 - human >gi|7... 252 2e-65
ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phos... 250 6e-65
ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phos... 250 6e-65
gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattu... 250 6e-65
gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphat... 250 7e-65
ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phos... 250 8e-65
ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyro... 249 1e-64
gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphata... 249 1e-64
pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse 249 1e-64
emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucle... 249 2e-64
sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodieste... 248 3e-64
dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus] 239 1e-61
ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus ... 239 1e-61
ref|NP_105837.1| (NC_002678) hypothetical protein [Mesorhizobium... 236 1e-60
ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo ... 236 1e-60
ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) ... 235 2e-60
gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster] 205 2e-51
Alignments
>ref|NP_495820.1| (NM_063419) Yeast YJ10 like [Caenorhabditis elegans]
 pir||T21487 hypothetical protein F28C6.4 - Caenorhabditis elegans
 emb|CAA92675.1| (Z68315) Similarity to Yeast hypothetical protein YJ10
           (SW:YJ10_YEAST)~cDNA EST yk160e12.5 comes from this
           gene~cDNA EST yk160e12.3 comes from this gene~cDNA EST
           yk317h4.3 comes from this gene~cDNA EST yk317h4.5 comes
           from this gene [Caenorhabditis ele>
          Length = 795

 Score =  924 bits (2364), Expect = 0.0
 Identities = 795/795 (100%), Positives = 795/795 (100%)

Query: 1   MKIIEFSRRTSERKWLDCEEAEEEDTKRKSIKFLRTHNHHQSENKELQELMISKKGKFWI 60
           MKIIEFSRRTSERKWLDCEEAEEEDTKRKSIKFLRTHNHHQSENKELQELMISKKGKFWI
Sbjct: 1   MKIIEFSRRTSERKWLDCEEAEEEDTKRKSIKFLRTHNHHQSENKELQELMISKKGKFWI 60

Query: 61  SRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
           SRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS
Sbjct: 61  SRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120

Query: 121 SKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTA 180
           SKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTA
Sbjct: 121 SKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTA 180

Query: 181 NWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN 240
           NWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN
Sbjct: 181 NWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN 240

Query: 241 TNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLI 300
           TNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLI
Sbjct: 241 TNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLI 300

Query: 301 VCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSST 360
           VCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSST
Sbjct: 301 VCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSST 360

Query: 361 IFDVFNMPIPIESYGISLINYFSDDEEEYFEKQHNQFRRIVQAKHLAISDICDENCDYSD 420
           IFDVFNMPIPIESYGISLINYFSDDEEEYFEKQHNQFRRIVQAKHLAISDICDENCDYSD
Sbjct: 361 IFDVFNMPIPIESYGISLINYFSDDEEEYFEKQHNQFRRIVQAKHLAISDICDENCDYSD 420

Query: 421 KFIKSALKKWFLTVQSELIGSASEVPNKSLGVCVFLLLVALTLSMGLWNLHLSKSDFFIF 480
           KFIKSALKKWFLTVQSELIGSASEVPNKSLGVCVFLLLVALTLSMGLWNLHLSKSDFFIF
Sbjct: 421 KFIKSALKKWFLTVQSELIGSASEVPNKSLGVCVFLLLVALTLSMGLWNLHLSKSDFFIF 480

Query: 481 LINITYFASSLIEEEHEIWYYLGSTVVAIRALRNFKIWNKTEVKSIFFLAFLHRIACSYT 540
           LINITYFASSLIEEEHEIWYYLGSTVVAIRALRNFKIWNKTEVKSIFFLAFLHRIACSYT
Sbjct: 481 LINITYFASSLIEEEHEIWYYLGSTVVAIRALRNFKIWNKTEVKSIFFLAFLHRIACSYT 540

Query: 541 QSTRRRWIMDSSLLPPSIFSDTLDFQPNNLNTILNEYPIIVILTCSLFWMYGYKQSKFHI 600
           QSTRRRWIMDSSLLPPSIFSDTLDFQPNNLNTILNEYPIIVILTCSLFWMYGYKQSKFHI
Sbjct: 541 QSTRRRWIMDSSLLPPSIFSDTLDFQPNNLNTILNEYPIIVILTCSLFWMYGYKQSKFHI 600

Query: 601 ILPMVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIVPVSQILLLL 660
           ILPMVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIVPVSQILLLL
Sbjct: 601 ILPMVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIVPVSQILLLL 660

Query: 661 VIYNMGKLFSKLNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQL 720
           VIYNMGKLFSKLNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQL
Sbjct: 661 VIYNMGKLFSKLNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQL 720

Query: 721 MLYTFSGPILFLCGCNASSCTSLLNHLFSYRISSMCTSLICLYIFQNHLFIWSVYSPKVV 780
           MLYTFSGPILFLCGCNASSCTSLLNHLFSYRISSMCTSLICLYIFQNHLFIWSVYSPKVV
Sbjct: 721 MLYTFSGPILFLCGCNASSCTSLLNHLFSYRISSMCTSLICLYIFQNHLFIWSVYSPKVV 780

Query: 781 YDMAHVIFFGLIGLL 795
           YDMAHVIFFGLIGLL
Sbjct: 781 YDMAHVIFFGLIGLL 795
>sp|Q09782|YA93_SCHPO HYPOTHETICAL 85.7 KD PROTEIN C13G6.03 IN CHROMOSOME I
 pir||S62432 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 pir||T37638 major facilitator protein homolog - fission yeast
           (Schizosaccharomyces pombe)
 emb|CAA91096.1| (Z54308) putative major facilitator superfamily protein
           [Schizosaccharomyces pombe]
          Length = 758

 Score =  677 bits (1729), Expect = 0.0
 Identities = 242/773 (31%), Positives = 382/773 (49%), Gaps = 53/773 (6%)

Query: 51  MISKKGKFWISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVI 110
             +  G FW    L +    L +  F       T       F       +   ++VF+++
Sbjct: 2   RFAFFGIFW----LQIFGSILFLLGFFPHKNDSTGKAMSNQFSP----PAVIDQVVFVMV 53

Query: 111 DAFRLSFLTSSKSPMSFTKSEITKKS-AKLFDAYARMPTVTLPRITAYLTGTLPSFGTVL 169
           DA R  F+ S    M FT+S +   +    F A+AR PTVT+PR+ A  TGT+P F  VL
Sbjct: 54  DALRADFVFSKSHNMPFTQSLLYNSTHGIGFSAFARSPTVTMPRLKALTTGTIPGFLDVL 113

Query: 170 TNLATAEMK-----TANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYT 224
            N+A ++         +W+ ++    KK+ F+GDDTW++L P +F KFEG TSFFVSDYT
Sbjct: 114 LNIAESDTGSSIEAQDSWVYQLNSFNKKIEFYGDDTWLKLFPSAFSKFEGTTSFFVSDYT 173

Query: 225 DVDNNVTRHLDTEL-SNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRI 283
           +VDNNVTR+ D  L S+ +HSWDALILHYLG+DHIGH  G SS  +  KL E+D +I RI
Sbjct: 174 EVDNNVTRNFDHALPSSLSHSWDALILHYLGVDHIGHLYGPSSPLLNIKLLEIDTIISRI 233

Query: 284 HKYLKSS-TSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEG--NKNYG 340
           +KYL+      +  S +++CGDHGM   G+HGG+S  ET   + +     E    NK   
Sbjct: 234 YKYLQEYDEKTNTHSLIVLCGDHGMNEVGNHGGSSSGETTAALSLLFPSNELSHINKPIL 293

Query: 341 NQDD-SLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISL---INYFSDDEEEYFEKQHNQ 396
           N DD       R+EQ+DV  TI  +  +PIP  + G  L      + D +        N 
Sbjct: 294 NMDDNPYSILERVEQVDVVPTICLLLGIPIPKGNMGKVLSPVTELWKDTKTAKMAALSNL 353

Query: 397 FR-RIVQAKHLAISDICDENCDYSDKFIKSALKKWFLTVQSELIGSASEVPNKSLGVCVF 455
           F+  +++   L  S++  +  D     I+ A       +QS+++  +S      + V + 
Sbjct: 354 FQLSLLKNPSLTTSELSTQFQDSDLNDIRLA----LENLQSQMVAQSSSYSLDRMLVAIS 409

Query: 456 LLLVALTLSMGLW-NLHLSKSD--FFIFLIN--ITYFASSLIEEEHEIWYYLGSTVVAIR 510
           +L     LS+ L+ NL+  K    F  F++   I  F+SS IEEEH IWY+   ++  ++
Sbjct: 410 ILGACSILSLILFRNLYNYKELLAFAPFVVQNIIIVFSSSFIEEEHVIWYFAAVSLSLLQ 469

Query: 511 ALRNFKIWNKTEVKSIFFLAFLHRIACSYTQSTRRRWIMDSSLLPPSIFSDTLDFQPNNL 570
            L        +    +F L+ + R   +  + +  R I+D  + P +     L      +
Sbjct: 470 LLNPKTRLAGSLQ--LFCLSIIKRWNQTGQKYSDLRDIVDDFIAPSTFMKTILCVTSAFM 527

Query: 571 NTILNEYPIIVILTCSLFWMYGYKQSKFHIILPMVS-HFLRLFELTQFNEVLMHFIRLSI 629
             I +  PI  +   S+F         F+ ++P++S H   L  +  F+      I  S+
Sbjct: 528 PAIRSPSPINFL--SSMF-------IAFYKLMPIISKHLNELPIIASFDYTFFVRIIWSL 578

Query: 630 LPISYST---GSVLAGCLPLLLAIVPVSQILLLLVIYNMGK--LFSKLNLGSVEFVTLCM 684
           L IS+ +      L   L L + ++   + + L ++Y++ +  +  +  L SV +     
Sbjct: 579 LLISFLSKPTFKQLRCQLSLFILLLTRLENMGLYLLYDIWQRTMPEEGTLASVMYYVAEQ 638

Query: 685 SSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFLCGCNASSCTSLL 744
            +FF  GNSNSL+T+ L+ AY GL SY    VG+ L    F+G  L+ C           
Sbjct: 639 VAFFSLGNSNSLATVDLSQAYTGLDSYNIFAVGILLFTSVFAGA-LWWCLHQPKRMMDRS 697

Query: 745 NHLFSYRISSMCTSLIC--LYIFQNHLFIWSVYSPKVVYDMAHVIFFGLIGLL 795
              F + +SS+  + +C   +I ++HLF+WSV+SPK++Y+ +    + L   L
Sbjct: 698 VKTF-WIMSSISLTFLCISCFIMRHHLFVWSVFSPKLLYNASWASMYFLAKCL 749
>ref|NP_012473.1| (NC_001142) Local Anesthetics Sensitive: involved in the attachment
           of glycosylphosphatidylinositol (GPI) anchors to
           proteins.; Las21p [Saccharomyces cerevisiae]
 sp|P40367|YJG2_YEAST HYPOTHETICAL 94.9 KD PROTEIN IN MRPL8-NUP82 INTERGENIC REGION
 pir||S50810 probable membrane protein YJL062w - yeast (Saccharomyces
           cerevisiae)
 emb|CAA84061.1| (Z34288) HRC830 [Saccharomyces cerevisiae]
 emb|CAA89353.1| (Z49337) ORF YJL062w [Saccharomyces cerevisiae]
          Length = 830

 Score =  676 bits (1726), Expect = 0.0
 Identities = 201/818 (24%), Positives = 343/818 (41%), Gaps = 102/818 (12%)

Query: 64  LVVCACALLVYSFVALDITPTPPTEEFGFKDG-NQESSSSPRLVFMVIDAFRLSFLTSSK 122
             + A  L +++F    I  T  +++   +D   Q      +LVF++IDA R  FL  S+
Sbjct: 12  AQLLAILLFIFAFFPRKIVLTGISKQDPDQDRDLQRDRPFQKLVFVIIDALRSDFLFDSQ 71

Query: 123 -SPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLA-----TAE 176
            S  +     +    A  + ++A  PTVTLPR+ +  TG+ PSF  +L N+A        
Sbjct: 72  ISHFNNVHQWLNTGEAWGYTSFANPPTVTLPRLKSITTGSTPSFIDLLLNVAQDIDSNDL 131

Query: 177 MKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVT-SFFVSDYTDVDNNVTRHLD 235
            +  +W+ +  +    + F GDDTW++L P+ +  F   T SFFVSD+T VDNNVTR+L 
Sbjct: 132 SEHDSWLQQFIQHNNTIRFMGDDTWLKLFPQQWFDFADPTHSFFVSDFTQVDNNVTRNLP 191

Query: 236 TELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQ 295
            +L      WD  ILHYLGLDHIGH  G  S  +  K +EMD ++  I+  +      D 
Sbjct: 192 GKLFQEWAQWDVAILHYLGLDHIGHKDGPHSKFMAAKHQEMDSILKSIYDEVLEHE-DDD 250

Query: 296 ESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFG----------REEGNKNYGNQDDS 345
           ++ + V GDHGM   G+HGG+S  ET   ++                        + D +
Sbjct: 251 DTLICVLGDHGMNELGNHGGSSAGETSAGLLFLSPKLAQFARPESQVNYTLPINASPDWN 310

Query: 346 LKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEYFEKQHNQFRRIVQAKH 405
            +    ++QID+  TI  +F MPIP+ S GI + ++      +    + N          
Sbjct: 311 FQYLETVQQIDIVPTIAALFGMPIPMNSVGIIIPDFLQLLPNKLASMKEN---------F 361

Query: 406 LAISDICDENCDYS-DKFIKSALKKWFLTVQSELIGSA--SEVPNKSLGVCVFLLLVALT 462
           + +  + D + + + D F    +     T+Q  L  SA     P  +L    FL++  + 
Sbjct: 362 MHLWKLSDHHGEVALDDFTAEDIYTKMYTIQETLTKSATNYNYPLLTLAFVGFLIITIIA 421

Query: 463 LSMGLWNLHLSKSDF---------FIFLINITYFASSLIEEEHEIWYYLGSTVVAI---- 509
           + + L                      ++ ++ FASS IEEEH++W+++ +   A+    
Sbjct: 422 IYVLLRYSGPDFWQLRVSSLSVLLVSIILGVSTFASSFIEEEHQLWWWIVTAFSAVPLFV 481

Query: 510 ---------------RALRNFKIWNKTEVKSIFF--LAFLHRIACSYTQSTRRRWIMDSS 552
                            +R+ K WN +  K I+   ++ L     S+         +   
Sbjct: 482 YRLNVLIIVRWFIMMACVRSIKFWNNSGQKFIYSNVMSNLLNQNPSWKWCLNMLTFLVLI 541

Query: 553 LLPPSIFSDTLDFQPNNLNTILNEYPIIVILTCS------LFWMYGYKQSKFHIILPMVS 606
           +   + F          L  +   Y I   +         LF      +  F      + 
Sbjct: 542 MA-SAGFQVLHFIVTTILVGLCFTYKISWEIVNGNQAEIPLFMHDLLAKIDFAPTESNLI 600

Query: 607 HFLRLFELTQFNEVLMHFIRLSILPISYS--TGSVLAGCLPLLLAIVPVSQILLLLVIYN 664
              R+F    +  V++  + L+ L +         +   + +LL     SQ +   +++ 
Sbjct: 601 VLARVF-FQAWAIVVISRLVLTKLKVLNKNYLIKDMKVYITILLMFQTSSQNIGQFLVFQ 659

Query: 665 M----------------GKLFSKLNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGL 708
           +                    SK+   ++  + L   +FF  G +NS+ST+ L +AY G+
Sbjct: 660 ILESQIFYFFQNIPTASLTSTSKIYFSNLVSLILQNFTFFQFGGTNSISTIDLGNAYHGV 719

Query: 709 SS-YQPILVGLQLMLYTFSGPILFL---CGCNASSCTSLLN---------HLFSYR-ISS 754
           SS Y   +VG+ + +  F+  I +       N +S  + +            F+Y  I  
Sbjct: 720 SSDYNIYVVGILMSVANFAPAIYWSMLPWSINYASIPAQVKLQTFIRSKLPAFTYHCIFG 779

Query: 755 MCTSLICLYIFQNHLFIWSVYSPKVVYDMAHVIFFGLI 792
            C    C+ + + HLFIWSV+SPK+ Y +      GL+
Sbjct: 780 TCLMTACV-VLRFHLFIWSVFSPKLCYFLGWNFVMGLL 816
>gb|AAK52677.1|AF321466_1 (AF321466) putative protein Gpi7p [Yarrowia lipolytica]
          Length = 860

 Score =  655 bits (1673), Expect = 0.0
 Identities = 224/861 (26%), Positives = 357/861 (41%), Gaps = 151/861 (17%)

Query: 61  SRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
             VL + A  L    F+   +     TE           +   + + MV+DAFR  F  S
Sbjct: 12  IVVLQLAAVLLFARGFLPSRVLLPGYTES-----RVSTEAPFQKAIIMVVDAFRSDFAFS 66

Query: 121 SKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLA-----TA 175
            +S        I    A  F A++  PTVTLPRI    TG+ P+F   + N+A     + 
Sbjct: 67  DQSNCPQLHKRINSGGAIPFTAHSTPPTVTLPRIKGLTTGSTPNFLDAVLNIAESDNSST 126

Query: 176 EMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLD 235
                +W+++  + G+K+H FGDDTWI+L P  F+  EG  SFFVSDYT+VDNNVTRH+D
Sbjct: 127 LANQDSWLAQASRDGRKIHMFGDDTWIKLFPGMFDDCEGTASFFVSDYTEVDNNVTRHID 186

Query: 236 TELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQ 295
           T+L      WD LILHYLGLDHIGH  G  S  +P K KEMDD+  +++       S D 
Sbjct: 187 TQLDQKTE-WDVLILHYLGLDHIGHKTGPESPFMPAKQKEMDDIFDKLYN------SCDD 239

Query: 296 ESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKN------YGNQDDSLKQP 349
           ++ LI+ GDHGM   G+HGG+S  ET   +V      E                D+ K  
Sbjct: 240 DTVLILLGDHGMNEVGNHGGSSAGETSAAMVFASPKFETAQLTETAETSPLPWTDTYKYH 299

Query: 350 PRIEQIDVSSTIFDVFNMPIPIESYGIS---LINYFS-DDEEEYFEKQHNQFRRIVQAKH 405
            R++Q D+  T+  +  +  P  + G+    ++  +S +D+    +   +Q  +I+Q + 
Sbjct: 300 SRMDQTDLVPTLTALLGLNTPKNNLGVLVSQMLGLWSPEDQLNVLKNNADQMVQILQGQA 359

Query: 406 LAISDICDENCDYSDKFIKS---ALKKWFLTVQSELIGSASEVPNKSLG----------V 452
              SD  +    Y              +    QS L  ++S      +           +
Sbjct: 360 SRESDAKEVYELYDTLNSNPSVKDYYNFLYEAQSYLTHASSNYNTNDMLGGIGLGLLSTI 419

Query: 453 CVFLLLVALTLSM-GLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYLGSTVVAIRA 511
               +  ALTL++ GL  L+       + +  I+ F SS +EEEH+IWY++ S  +A   
Sbjct: 420 LALTVFSALTLAVQGLKRLY----LIILLVYFISVFGSSTVEEEHQIWYWITSGWMAFLY 475

Query: 512 LRNFKIWNKTEVKSIFFLAFLHRIACSYTQSTRRRWIMDSSLLPPSIFSDTLDFQPNNLN 571
           +   +         +F   F+ R+  S+ Q+ ++    D  +   S        QP+   
Sbjct: 476 ISGSRNKFGDGFNWMFVQVFV-RMMISWNQTGQKFTKKDDIVTWLSKDG----NQPSLWI 530

Query: 572 TILNEYPIIVILTCSLFWMYGYKQ--SKFHIILPMVSHFLRL-FELTQ------------ 616
            IL  Y +      +  W YG+ +  SK   +L +++ F  + F++TQ            
Sbjct: 531 LILVTYGVAF----NKVWRYGFSKVESKLAFLLTLITTFASVGFKITQAWEAGEVVPAPL 586

Query: 617 -------------------FNEVLMHFIRLSIL--PISYS------TGSVLAGCLPLLLA 649
                                      I    L   +S +          L   L L L 
Sbjct: 587 LYLMGLPGTLNEVNARMAGLARFAFSTIAAGSLYRVLSLAGTDKVNLIRDLHAFLTLFLI 646

Query: 650 IVPVSQILLLL-----------------------VIYNMGKLFSK-LNLGSVEFVTLCMS 685
                Q + L                         IY    LF K + + SV  + L   
Sbjct: 647 TQSRIQNIPLFMVYYFLEIFLRKATNRSFIFSSRDIYQTEALFQKLVLVLSVSTLLLEQV 706

Query: 686 SFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFLCGC---------- 735
           SFF  GNSNS++++ L++AY G++ YQ   VG+   +  + GP+ +              
Sbjct: 707 SFFSMGNSNSMASIDLSNAYNGVTLYQIEFVGVLTFVSNWIGPLYWSTAGLSFLLEDHVR 766

Query: 736 ------------NASSCTSLLNHLFSYRIS--------SMCTSLICLYIFQNHLFIWSVY 775
                       +    T L+    + R+         ++   +I  +  + HLFIW+V+
Sbjct: 767 NAIFAKIAEKNNDVKLTTKLVQQALTLRVYVVLAFSSVAISAVMITCFFLREHLFIWTVF 826

Query: 776 SPKVVYDMAHVIF-FGLIGLL 795
           SPK++Y     +  F L+ ++
Sbjct: 827 SPKLLYQFVWTVLQFALVDVI 847
>dbj|BAA82620.1| (AB030280) phosphatidylinositolglycan class N short form [Mus
           musculus]
          Length = 798

 Score =  600 bits (1533), Expect = e-170
 Identities = 130/766 (16%), Positives = 230/766 (29%), Gaps = 112/766 (14%)

Query: 63  VLVVCACALLVYSFV--ALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
           +L      L+ + F     DI  T P               + RLV  V D  R   L  
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 121 SKSPMSFTKSEITK---KSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM 177
                +     I            ++ R+PT + P   A + G       V        +
Sbjct: 62  LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 178 KTANWISRIQKIGKKVHFFGDD-TWIRLL------PRSFEKFEGV--TSFFVSDYTDVDN 228
           +  +  +       K  +       + +          +          F   D T +D 
Sbjct: 122 EFDSLFNES-----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 229 NVTRHLDTELS----------NTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDD 278
            V   +                 N       LH LG+D  GH+   SS +  + +K++DD
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDD 236

Query: 279 VIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEG-NK 337
            +  I    K     D ++  I   DHGMT  GSHG   P ET  P V W  G +   N 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 338 NYGNQDDSLKQPPR--------IEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEY 389
           +    DD   +  R        + Q D++  +  +  +P P+ S GI  + Y ++     
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 390 FEKQHNQFRRIVQAKHLAISDICDENC-DYSDKFIKSALKKWFL---TVQSELIGSASEV 445
            E       +I++   + ++   +         F   +  +        +S +     + 
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFD- 415

Query: 446 PNKSLGVCVFLLLVALTLSM-GLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYLGS 504
                   V L    + L++ GL   H     F    + + +           + +   +
Sbjct: 416 ------EVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGF-----------VGWMSYT 458

Query: 505 TVVAIRALRNFKIWNKTEVKSIFFLAFLHRI------ACSYTQSTRRRWIMDSSLLPPSI 558
           +++ I++  N     + E K    L     I      AC               LLP  I
Sbjct: 459 SLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 559 FSDTL---------------DFQPNNLNTILNEYPIIVILTCSLFWMY----GYKQSKFH 599
           +   L                 + + +  +L     I +L  S F+ Y    G       
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGW 578

Query: 600 IILPMVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLL-LAIVPVSQILL 658
             L  +    ++     +       + L++ P+    G      L +    +V +  + +
Sbjct: 579 PFLTQLWTRAKI-TFLSWA---FFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAV 634

Query: 659 LLVIYNMGKLFSKL----NLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPI 714
           +  +        K      L  +    L M   + T +  SL          GL     I
Sbjct: 635 VTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHH--SLLKKE------GLPLMNQI 686

Query: 715 LVGLQLMLYTFSGPILFLCGCNASSCTSLLNHLFSYRISSMCTSLI 760
           +    L     +            S T+L   L S  +S M T L+
Sbjct: 687 VSWATLASSLVA---------PLLSSTALSQRLASILLSLMSTYLL 723
>gb|AAH21148.1|AAH21148 (BC021148) Similar to phosphatidylinositol glycan, class N [Mus
           musculus]
          Length = 826

 Score =  598 bits (1526), Expect = e-169
 Identities = 130/766 (16%), Positives = 230/766 (29%), Gaps = 112/766 (14%)

Query: 63  VLVVCACALLVYSFV--ALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
           +L      L+ + F     DI  T P               + RLV  V D  R   L  
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 121 SKSPMSFTKSEITK---KSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM 177
                +     I            ++ R+PT + P   A + G       V        +
Sbjct: 62  LDEDGNSRAPFIRNVIIHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 178 KTANWISRIQKIGKKVHFFGDD-TWIRLL------PRSFEKFEGV--TSFFVSDYTDVDN 228
           +  +  +       K  +       + +          +          F   D T +D 
Sbjct: 122 EFDSLFNES-----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 229 NVTRHLDTELS----------NTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDD 278
            V   +                 N       LH LG+D  GH+   SS +  + +K++DD
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDD 236

Query: 279 VIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEG-NK 337
            +  I    K     D ++  I   DHGMT  GSHG   P ET  P V W  G +   N 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 338 NYGNQDDSLKQPPR--------IEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEY 389
           +    DD   +  R        + Q D++  +  +  +P P+ S GI  + Y ++     
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 390 FEKQHNQFRRIVQAKHLAISDICDENC-DYSDKFIKSALKKWFL---TVQSELIGSASEV 445
            E       +I++   + ++   +         F   +  +        +S +     + 
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFD- 415

Query: 446 PNKSLGVCVFLLLVALTLSM-GLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYLGS 504
                   V L    + L++ GL   H     F    + + +           + +   +
Sbjct: 416 ------EVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGF-----------VGWMSYT 458

Query: 505 TVVAIRALRNFKIWNKTEVKSIFFLAFLHRI------ACSYTQSTRRRWIMDSSLLPPSI 558
           +++ I++  N     + E K    L     I      AC               LLP  I
Sbjct: 459 SLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 559 FSDTL---------------DFQPNNLNTILNEYPIIVILTCSLFWMY----GYKQSKFH 599
           +   L                 + + +  +L     I +L  S F+ Y    G       
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGW 578

Query: 600 IILPMVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLL-LAIVPVSQILL 658
             L  +    ++     +       + L++ P+    G      L +    +V +  + +
Sbjct: 579 PFLTQLWTRAKI-TFLSWA---FFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAV 634

Query: 659 LLVIYNMGKLFSKL----NLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPI 714
           +  +        K      L  +    L M   + T +  SL          GL     I
Sbjct: 635 VTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHH--SLLKKE------GLPLMNQI 686

Query: 715 LVGLQLMLYTFSGPILFLCGCNASSCTSLLNHLFSYRISSMCTSLI 760
           +    L     +            S T+L   L S  +S M T L+
Sbjct: 687 VSWATLASSLVA---------PLLSSTALSQRLASILLSLMSTYLL 723
>ref|NP_038812.1| (NM_013784) phosphatidylinositol glycan, class N [Mus musculus]
 dbj|BAA82619.1| (AB030279) phosphatidylinositolglycan class N [Mus musculus]
          Length = 931

 Score =  588 bits (1501), Expect = e-166
 Identities = 130/766 (16%), Positives = 230/766 (29%), Gaps = 112/766 (14%)

Query: 63  VLVVCACALLVYSFV--ALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
           +L      L+ + F     DI  T P               + RLV  V D  R   L  
Sbjct: 2   LLFFALGLLIHFVFFVSIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 121 SKSPMSFTKSEITK---KSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM 177
                +     I            ++ R+PT + P   A + G       V        +
Sbjct: 62  LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 178 KTANWISRIQKIGKKVHFFGDD-TWIRLL------PRSFEKFEGV--TSFFVSDYTDVDN 228
           +  +  +       K  +       + +          +          F   D T +D 
Sbjct: 122 EFDSLFNES-----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 229 NVTRHLDTELS----------NTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDD 278
            V   +                 N       LH LG+D  GH+   SS +  + +K++DD
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGVDTNGHAHRPSSREYKDNIKKVDD 236

Query: 279 VIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEG-NK 337
            +  I    K     D ++  I   DHGMT  GSHG   P ET  P V W  G +   N 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 338 NYGNQDDSLKQPPR--------IEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEY 389
           +    DD   +  R        + Q D++  +  +  +P P+ S GI  + Y ++     
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 390 FEKQHNQFRRIVQAKHLAISDICDENC-DYSDKFIKSALKKWFL---TVQSELIGSASEV 445
            E       +I++   + ++   +         F   +  +        +S +     + 
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFKLLSDSQQLDILRKARSYIKQEKFD- 415

Query: 446 PNKSLGVCVFLLLVALTLSM-GLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYLGS 504
                   V L    + L++ GL   H     F    + + +           + +   +
Sbjct: 416 ------EVVSLCEELIDLALRGLSYYHTYDRLFLGINVAVGF-----------VGWMSYT 458

Query: 505 TVVAIRALRNFKIWNKTEVKSIFFLAFLHRI------ACSYTQSTRRRWIMDSSLLPPSI 558
           +++ I++  N     + E K    L     I      AC               LLP  I
Sbjct: 459 SLLIIKSHSNIPKGTRKEGKKPHCLLLYSFIATGVLVACFLMIQACPWTYYVYCLLPVPI 518

Query: 559 FSDTL---------------DFQPNNLNTILNEYPIIVILTCSLFWMY----GYKQSKFH 599
           +   L                 + + +  +L     I +L  S F+ Y    G       
Sbjct: 519 WYAVLREHEVIQDLVESLLTFPRSHFVAYLLVFTLGIEVLVLSFFYRYMLTAGLIVFAGW 578

Query: 600 IILPMVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLL-LAIVPVSQILL 658
             L  +    ++     +       + L++ P+    G      L +    +V +  + +
Sbjct: 579 PFLTQLWTRAKI-TFLSWA---FFSLLLAVFPLMPVVGRKPNLSLVMGAGFLVLLLSLAV 634

Query: 659 LLVIYNMGKLFSKL----NLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPI 714
           +  +        K      L  +    L M   + T +  SL          GL     I
Sbjct: 635 VTTLGKRNIKLVKGELLVLLLQMLSTVLSMYVVYSTHH--SLLKKE------GLPLMNQI 686

Query: 715 LVGLQLMLYTFSGPILFLCGCNASSCTSLLNHLFSYRISSMCTSLI 760
           +    L     +            S T+L   L S  +S M T L+
Sbjct: 687 VSWATLASSLVA---------PLLSSTALSQRLASILLSLMSTYLL 723
 Score = 38.0 bits (88), Expect = 0.69
 Identities = 41/338 (12%), Positives = 93/338 (27%), Gaps = 29/338 (8%)

Query: 452 VCVFLLLVALTLSMGLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYLGSTVVAIRA 511
           V   L+       + L   +         ++   +   + +    +I +   +    + A
Sbjct: 545 VAYLLVFTLGIEVLVLSFFYRYM-LTAGLIVFAGWPFLTQLWTRAKITFLSWAFFSLLLA 603

Query: 512 LRNFKIWNKTEVKSIFFL--------------AFLHRIACSYTQSTRRRWIMDSSLLPPS 557
           +         +      +                L +      +      ++       S
Sbjct: 604 VFPLMPVVGRKPNLSLVMGAGFLVLLLSLAVVTTLGKRNIKLVKGELLVLLLQMLSTVLS 663

Query: 558 IFSDTLDFQPNNLN---TILNEYPIIVI-LTCSLFWMYGYKQSKFHIILPMVSHFLRLFE 613
                     + L      L    +    L  SL        +    +  ++   +  + 
Sbjct: 664 -MYVVYSTHHSLLKKEGLPLMNQIVSWATLASSLVAPLLSSTALSQRLASILLSLMSTYL 722

Query: 614 LTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIV--PVSQILLLLVIYNMGKLF-- 669
           L       +  + LS L   +          P +         Q      I    +L   
Sbjct: 723 LLSTGYEALFPLVLSCLMFVWIQVEQETLQQPGVSCKQKLTSIQFTCDTDIAQFRQLCPD 782

Query: 670 -SKLNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGP 728
             +     V F+    ++FF TGN  S+++  L S Y  L+ + P ++G  +M       
Sbjct: 783 DIRRAFFLVFFLL---TAFFGTGNIASINSFDLASVYCFLTVFSPFMMGALMMWKILIPF 839

Query: 729 ILFLCGCNASSCTS-LLNHLFSYRISSMCTSLICLYIF 765
           +L +C   A   T+ L +      +  +   +   + F
Sbjct: 840 VLVMCAFEAVQITTQLSSKGLFLVVLIISDIMALHFFF 877
>ref|NP_012756.1| (NC_001143) Required for GPI anchor synthesis; Mcd4p [Saccharomyces
           cerevisiae]
 sp|P36051|YKQ5_YEAST HYPOTHETICAL 105.7 KD PROTEIN IN TPK3-PIR1 INTERGENIC REGION
 pir||S37786 hypothetical protein YKL165c - yeast (Saccharomyces cerevisiae)
 emb|CAA81489.1| (Z26877) unknown [Saccharomyces cerevisiae]
 emb|CAA82007.1| (Z28165) ORF YKL165c [Saccharomyces cerevisiae]
 prf||2118404A ORF [Saccharomyces cerevisiae]
          Length = 919

 Score =  553 bits (1412), Expect = e-156
 Identities = 122/725 (16%), Positives = 230/725 (30%), Gaps = 88/725 (12%)

Query: 66  VCACALLVYSFV--ALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKS 123
           +    L    ++    DI    P         +  +  + RL  +V D  R        +
Sbjct: 10  LAVGVLFHLFYLWSIFDIYFISPLVHGMSPYQSTPTPPAKRLFLIVGDGLRADTTFDKVT 69

Query: 124 P---------MSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLAT 174
                       F +S +   +A    ++ RMPT + P   A + G       V     +
Sbjct: 70  HPVSGKTEFLAPFIRSLVMN-NATYGISHTRMPTESRPGHVAMIAGFYEDVSAVTKGWKS 128

Query: 175 AEMKTANWISRIQKIGKKVHF-FGDDTWIRLLP---------RSFEKFEGVTSFFVSDYT 224
             +   ++ ++         + FG    + +            ++        F  S   
Sbjct: 129 NPVNFDSFFNQSTH-----TYSFGSPDILPMFKDGASDPNKVDTWMYDHTFEDFTQSSI- 182

Query: 225 DVDNNVTRHLDTELSNT----------NHSWDALILHYLGLDHIGHSLGGSSSKIPEKLK 274
           ++D  V RHLD    N+              +   LH LG D  GHS    S++  + +K
Sbjct: 183 ELDAFVFRHLDQLFHNSTLNSTLDYEIRQDGNVFFLHLLGCDTAGHSYRPYSAEYYDNVK 242

Query: 275 EMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREE 334
            +DD I  +   +      D ++  I   DHGM+A GSHG   P+ TR P+V W  G  +
Sbjct: 243 YIDDQIPILIDKVNKF-FADDKTAFIFTADHGMSAFGSHGDGHPNNTRTPLVAWGAGLNK 301

Query: 335 GNKNYGNQDDSLKQPP--------RIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDE 386
              N     D+  +           ++Q D++S +  +  +  P  S G   I Y    E
Sbjct: 302 PVHNPFPVSDNYTENWELSSIKRNDVKQADIASLMSYLIGVNYPKNSVGELPIAYIDGKE 361

Query: 387 EEYFEKQHNQFRRIVQAKHLAISDICDENCDYSDKFIK--SALKKWFLTVQSELIGSASE 444
            +     +N  R I++   +   ++ D    Y + F     +   +   +   LI   SE
Sbjct: 362 SDKLAALYNNARSILEQYLVKQDEVIDSQFFYKEYFKFVEKSHSHYLEEI-ETLIQRISE 420

Query: 445 VPNKSLGVCVFLLLVALTLSM-GLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYLG 503
             N      + L    + +++ GL  L      F   ++   +              ++ 
Sbjct: 421 GENYLEQEAITLTEELMQITLEGLHYLTTYNWRFIRTIVTFGFVG------------WIF 468

Query: 504 STVVAIRALRNFKIWNKTEVKSIFFLAFLHRIACSYTQ----STRRRWIMDSSLLPPSIF 559
            + +        +     +  S    A    I                     L P   +
Sbjct: 469 FSFIIFLKSFILENVIDDQKASPLSHAVFGSIGILLNWILFYQHSPFNFYMYLLFPLYFW 528

Query: 560 SDTLDFQPNNLNTILNEYPII-----VILTCSLFWMYGYKQSKF--HIILPMVSHFLRLF 612
           S     +    + I   +        V++T S+  +Y      F       ++++ L  +
Sbjct: 529 SYIFTNRSVLRSGIKEFFKGTSPWKRVLITISIISVYEGIVYGFFHRWTFTLITNILAFY 588

Query: 613 ELTQFNEVLMHFIRLSILPISYSTGS-------VLAGCLPLLLAIVPVSQILLLLVIYNM 665
                   L   I   I  +  ST +            + L   ++ +S    L  I++ 
Sbjct: 589 PFICGVRELSVNILWIITSVLLSTFTLFDAVKIEDLNQIHLAGLLIILSAFYALYKIHSR 648

Query: 666 GKLFSKLNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTF 725
              +++        +   M +   T    S+ +L L     GL     +   +   +  F
Sbjct: 649 INSYTRAIFAIQISLVAAMLAV--THR--SVISLQLRQ---GLPRESQVAGWIIFFVSLF 701

Query: 726 SGPIL 730
             PIL
Sbjct: 702 VMPIL 706
>gb|AAF58853.1| (AE003831) CG2292 gene product [Drosophila melanogaster]
          Length = 874

 Score =  461 bits (1174), Expect = e-128
 Identities = 93/640 (14%), Positives = 178/640 (27%), Gaps = 92/640 (14%)

Query: 59  WISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFL 118
           WI+  LVV    L     +                        + RLV +V D FR    
Sbjct: 2   WIAYALVVHVLLLGSIFVIYFRSPVITGLTPQKHLLYYGLEPPANRLVLIVTDGFRADSF 61

Query: 119 TSS-KSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM 177
                  +   +     +   +  +  R+PT T P     + G       VL    +  +
Sbjct: 62  FEENCRYVPNLRKIFL-REGVVGVSRTRVPTETRPGHITLIAGLYEDPSAVLRGWKSNPI 120

Query: 178 KTANWISRIQKIGKKVHFFGDD-TWIRLLPRSFE------KFEGVTSFFVS--DYTDVDN 228
                 +R  +      +       + +            +F      F    D  + D 
Sbjct: 121 DFDTVFNRSSQ-----TYAWGANDVLNVFSHVSNGGEINLRFYNHDLDFSPGYDAYEEDE 175

Query: 229 NVTRHLDTELSNTNH-----SWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRI 283
            V + +   L                LH LGLD  GH     + K    L++ +  +  I
Sbjct: 176 WVFKRVKLLLQQKREALQRAQNVVFFLHLLGLDTAGHVHKPGAPKFRRTLEKTEKGVYAI 235

Query: 284 HKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQD 343
           ++  +     D+ +  ++  DHGMT +G                 +   + G + +   +
Sbjct: 236 YQEFE-RVFPDKRTAYLLTADHGMTDSG---------------ASRAVPKPGGRTFMPNN 279

Query: 344 DSLKQPP-RIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEYFEKQHNQFRRIVQ 402
           +    P   +EQ  ++  +  +  +  P+ ++G   + Y +  +E      H    ++++
Sbjct: 280 EGPAMPLHELEQAQLTPLMSALLGLAPPMNNFGKLPLGYLNVSKEYEAMAAHVNALQLLE 339

Query: 403 AKHLAISDICDENC----DYSDKFIKSALKKWFLTVQSELIGSASEVPNKSLGVCVFLLL 458
                                D     A+K++  T+                     L +
Sbjct: 340 QYVALQKQHKKGFFADILLEYDVLNAEAIKRYKDTIVQLQKKREY-----------SLCI 388

Query: 459 VALTLSM-----GLWNLHLSKSDFFIFLINITYFASSLIEEEHEIWYYL----GSTVVAI 509
               + M     G+   H       +         S+ +     I+  L     S V  +
Sbjct: 389 DKSQVIMSQALEGIDYYHGYYRRVLLLSTT-----STFLGWMFYIYRLLSRNRASKVELV 443

Query: 510 RALRNFKIWNKTEVKSIFFLAFLHRIACSYTQSTRRRWIMDSSLLP-PSIFSDTLDFQPN 568
               N  +       SI     +  I C  +Q T    I    LLP          +  N
Sbjct: 444 LERSNKIVRV-----SIVSSVIVLII-CLLSQGT-PLDISFYLLLPYFVWLKALQPWNIN 496

Query: 569 NLNTILNEYPIIVILTCSLFWMYGYKQSKFHIILPMVSHFLRLFELTQFNEV-------- 620
             ++  + Y  +  L  S++ +         ++       L       F           
Sbjct: 497 FSSSPASAYS-VPALQTSMWQLVLLIACAELMVFTFFERRLIALCFCVFACYNSWENFQW 555

Query: 621 --------LMHFIRLSILPISYSTGSVLAGCLPLLLAIVP 652
                   L   + LS  P+   +     G L     IV 
Sbjct: 556 KSRDFFSWLALVLILSCFPLLPLSVGYQNGYLLGAGVIVI 595
>ref|NP_186787.1| (NM_111004) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
 gb|AAF24617.1|AC010870_10 (AC010870) putative phosphatidylinositolglycan class N short form
           [Arabidopsis thaliana]
          Length = 921

 Score =  409 bits (1043), Expect = e-113
 Identities = 83/520 (15%), Positives = 157/520 (29%), Gaps = 68/520 (13%)

Query: 48  QELMISKKGKFWISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVF 107
                 K+ + W+  VL V   A+ + S   +                      + RLV 
Sbjct: 34  SRRRWLKRRETWL-VVLGVALHAVYMLSIFDIYFKTPIVHGMDPVPPR-FSEPPAKRLVL 91

Query: 108 MVIDAFRLSFLTSSKSPMSFTKSEITK---KSAKLFDAYARMPTVTLPRITAYLTGTLPS 164
           ++ D  R            +    +        +   ++AR PT + P   A + G    
Sbjct: 92  LISDGLRADKFFEPDEEGKYRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYED 151

Query: 165 FGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLL-----PRSFE-KFEGVTSF 218
              V        ++  +  ++ +        FG    I +        ++         F
Sbjct: 152 PSAVTKGWKANPVEFDSVFNQSRH----TFAFGSPDIIPIFCSALPHSTWNSYPHEYEDF 207

Query: 219 FVSDYTDVDNNVTRHLDTELSNTNHSWD----------ALILHYLGLDHIGHSLGGSSSK 268
             +D + +D       +  L+ ++               + LH LG D  GH+    SS 
Sbjct: 208 -ATDASFLDEWSFDQFEGLLNRSHADPKLKELLHQDKLVVFLHLLGCDSNGHAHRPYSSI 266

Query: 269 IPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIW 328
               +K +D +  R++  L+     D  +  I   DHGM+  GSHG   P  T  P+V W
Sbjct: 267 YLNNVKVVDKIAERVYHLLEDYYR-DNRTSYIFTADHGMSDKGSHGDGHPTNTDTPLVAW 325

Query: 329 KFGREEGNKNYG--------------------NQDDSLKQPPR--IEQIDVSSTIFDVFN 366
             G +      G                      D  L++  R  + Q D++  +  +  
Sbjct: 326 GAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRVERVDVNQADIAPLMSTLLG 385

Query: 367 MPIPIESYGISLINYFSDDEEEYFEKQHNQFRRIVQAKHLAISDICDENCDYSDKFIKSA 426
           +P P+ S G   + Y   +E E  E      ++I+  + L  S I   N  +   F    
Sbjct: 386 LPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQIL-NQLLRKSYIKSSNSLFFKPFKPLV 444

Query: 427 LKKW-FLTVQSELIGSASEVPNKSLGVCVFLLLVALTLSMGLWNLHLSKSDFFIFLINIT 485
              +    +   +   + E   K       L L       GL           + +I + 
Sbjct: 445 HHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLE------GLHYFQTYDWLMLMTVITL- 497

Query: 486 YFASSLIEEEHEIWYYLGSTVVAIRALRNFKIWNKTEVKS 525
                         + +   +  ++   +       +   
Sbjct: 498 ----------GYTGWMIVLALHVLQCYSSLSGDLSKKEHL 527
 Score = 34.9 bits (80), Expect = 5.5
 Identities = 16/56 (28%), Positives = 30/56 (53%)

Query: 679 FVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFLCG 734
           F+ L   +FF TGN  S+++  ++S Y  ++ + P L+   L+   F   +L +C 
Sbjct: 778 FMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFIPFMLVICA 833
>pir||T02245 hypothetical protein P1.11659_3 - human
 gb|AAC07985.1| (AC004472) P1.11659_3 [Homo sapiens]
          Length = 880

 Score =  408 bits (1039), Expect = e-112
 Identities = 110/433 (25%), Positives = 178/433 (40%), Gaps = 51/433 (11%)

Query: 59  WISRV--LVVCACALLVYSFVAL----------DITPTPPTEEFGFK---DGNQESSSSP 103
           +++ V  L     AL    F+               P P +  +G +        +S   
Sbjct: 9   FLAWVCFLFYAGIALFTSGFLLTRLELTNHSSCQEPPGPGSLPWGSQGKPGACWMASRFS 68

Query: 104 RLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLP 163
           R+V ++IDA R  F        S    EI    A+L+ +    PT T+ R+ A  TG+LP
Sbjct: 69  RVVLVLIDALRFDFAQP---QHSHRILEIQPHHARLYRSQVDPPTTTMQRLKALTTGSLP 125

Query: 164 SFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDY 223
           +F    +N A+  +   N I ++   G++V F GDDTW  L P +F K     SF V D 
Sbjct: 126 TFIDAGSNFASHAIVEDNLIKQLTSAGRRVVFMGDDTWKDLFPGAFSKAFFFPSFNVRDL 185

Query: 224 TDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRI 283
             VDN +  HL   + +    WD LI H+LG+DH GH  G    ++ +KL +MD VI  +
Sbjct: 186 DTVDNGILEHLYPTMDSG--EWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGL 243

Query: 284 HKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQD 343
            + L+       ++ L+V GDHGMT  G HGG S  E    + ++               
Sbjct: 244 VERLE------NDTLLVVAGDHGMTTNGDHGGDSELEVSAALFLYS-------PTAVFPS 290

Query: 344 DSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEE--------YFEKQHN 395
              ++P  I Q+ +  T+  +  +PIP  + G  +   FS  E+              H 
Sbjct: 291 TPPEEPEVIPQVSLVPTLALLLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHL 350

Query: 396 QFRR---IVQAKHLAISDI--CDENCDYSDKFIKSALKKWFLT----VQSELIGSASEVP 446
             ++    +     A  D+   + +   +     SA  +W L      ++ L    +E+ 
Sbjct: 351 NAQQVSRFLHTYSAATQDLQAKELHQLQNLFSKASADYQWLLQSPKGAEATLPTVIAELQ 410

Query: 447 NKSLGVCVFLLLV 459
               G    + + 
Sbjct: 411 QFLRG-ARAMCIE 422
 Score = 82.0 bits (201), Expect = 4e-14
 Identities = 15/73 (20%), Positives = 26/73 (35%), Gaps = 3/73 (4%)

Query: 675 GSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQ---PILVGLQLMLYTFSGPILF 731
               +  +   +F+ TG+      +   +A+VG          L  L +   TF+  +LF
Sbjct: 741 AVSAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLF 800

Query: 732 LCGCNASSCTSLL 744
             GC        L
Sbjct: 801 AVGCPLLLLWPFL 813
>dbj|BAA82663.1| (AB030316) phosphatidylinositolglycan class N [Mus musculus]
          Length = 391

 Score =  406 bits (1035), Expect = e-112
 Identities = 76/395 (19%), Positives = 126/395 (31%), Gaps = 39/395 (9%)

Query: 63  VLVVCACALLVYSFV--ALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
           +L      L+ + F     DI  T P               + RLV  V D  R   L  
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 121 SKSPMSFTKSEITK---KSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM 177
                +     I            ++ R+PT + P   A + G       V        +
Sbjct: 62  LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 178 KTANWISRIQKIGKKVHFFGDD-TWIRLL------PRSFEKFEGV--TSFFVSDYTDVDN 228
           +  +  +       K  +       + +          +          F   D T +D 
Sbjct: 122 EFDSLFNES-----KYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 229 NVTRHLDTELS----------NTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDD 278
            V   +                 N       LH LG+D  GH+   SS +  + +K++DD
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDD 236

Query: 279 VIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEG-NK 337
            +  I    K     D ++  I   DHGMT  GSHG   P ET  P V W  G +   N 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 338 NYGNQDDSLKQPPR--------IEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEY 389
           +    DD   +  R        + Q D++  +  +  +P P+ S GI  + Y ++     
Sbjct: 297 SAQQYDDEFLKEWRLENWKRRDVNQADIAPLMASLIGVPFPLNSVGILPVGYLNNTGLFK 356

Query: 390 FEKQHNQFRRIVQAKHLAISDICDENC-DYSDKFI 423
            E       +I++   + ++   +         F 
Sbjct: 357 AESMFTNAVQILEQFKVKMTQKKEATLPFLFTPFK 391
>ref|NP_491097.1| (NM_058696) Y54E10BR.1.p [Caenorhabditis elegans]
          Length = 348

 Score =  371 bits (945), Expect = e-101
 Identities = 70/361 (19%), Positives = 126/361 (34%), Gaps = 35/361 (9%)

Query: 59  WISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFL 118
           W   +  +    +L+YS   +  T +P       +  N + + + R+  +  D  R    
Sbjct: 3   WKFLIASITVHLVLIYSIFDVYYT-SPLVHGIPPQFINSQEAPAKRIFIISADGLRYDTF 61

Query: 119 TSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMK 178
                   +  S + ++      + + +PT + P   A   G       V        ++
Sbjct: 62  NKYPDKSPYLHSIMNERKGIYGLSRSHIPTESRPGHVAIFAGITEDISAVAKGWKKNPVQ 121

Query: 179 TANWISRIQKIGKKVHFFGDD-TWIRLLPR-----SFEKFEGVTSFFVSDYTDVDNNVTR 232
             +  +R         +       + L        SF        F   D +++D  V  
Sbjct: 122 FDSVFNRSS-----YSWMWGSPDIVNLFDDLPNAESFSYSADEEDFASKDASNLDKWVFE 176

Query: 233 HLDTEL----------SNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGR 282
           H +  L                     LH LG+D  GH     S +  + +K +D  I +
Sbjct: 177 HFENFLETAKTDEALNDKMREQKSIFFLHLLGIDTNGHGNKPMSRQYIDNIKVVDSGIEK 236

Query: 283 IHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQ 342
             ++L  +   D ++  +   DHGMT  GSHG  S DE   P V W  G ++G       
Sbjct: 237 -VQHLVDAFFGDHKTAWLFTSDHGMTDWGSHGAGSDDEVLTPFVAWGAGVKQGGPK---- 291

Query: 343 DDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEY-FEKQHNQFRRIV 401
                    + QID++  I  +   PIP+ S GI  +   +     Y F+     F++++
Sbjct: 292 -------LDLNQIDLAPLISALIGCPIPVNSMGILPVQMMNSKGSSYEFKAIEANFKQVI 344

Query: 402 Q 402
            
Sbjct: 345 N 345
>ref|NP_064419.1| (NM_020035) phosphatidylinositol glycan, class O [Mus musculus]
 dbj|BAA96254.1| (AB038560) Pig-o [Mus musculus]
          Length = 1101

 Score =  362 bits (922), Expect = 1e-98
 Identities = 110/465 (23%), Positives = 177/465 (37%), Gaps = 65/465 (13%)

Query: 44  NKELQELMISKKGKFWISRV--LVVCACALLVYSFVAL----------DITPTPPTEEFG 91
           N      M       +++ V  L     AL    F+               P P    +G
Sbjct: 2   NILFSPRMRKVSVLLFLAWVCFLFYAGIALFTSGFLLTRLELTNQSSCQELPGPGPLPWG 61

Query: 92  F---KDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMS--------------FTKSEI-- 132
                      S   R+V ++IDA R  F    +S +                 +  +  
Sbjct: 62  SHGKPGACWMPSRFSRVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGSLQRILES 121

Query: 133 TKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTANWISRIQKIGKK 192
                +L+ +    PT T+ R+ A  TG+LP+F    +N A+  +   N I ++   G++
Sbjct: 122 QPHHGRLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFASHAIVEDNVIQQLNSAGRR 181

Query: 193 VHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSNTNHSWDALILHY 252
           V F GDDTW  L P +F +    +SF V D   VDN +  HL   L     SWD LI H+
Sbjct: 182 VVFMGDDTWRDLFPGAFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDGG--SWDVLIAHF 239

Query: 253 LGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGS 312
           LG+DH GH  G    ++ +KL +MD VI  + + L+       ++ L+V GDHGMT  G 
Sbjct: 240 LGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLIERLE------NDTLLVVAGDHGMTMNGD 293

Query: 313 HGGASPDETRVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIE 372
           HGG S  E    + ++                  ++P  I Q+ +  T+  +  +PIP  
Sbjct: 294 HGGDSELEVSAALFLYS-------PTALFPSVPPEEPEVIPQVSLVPTLALLLGLPIPFG 346

Query: 373 SYGISLINYFSDDEEE---------YFEKQHNQFRR---IVQAKHLAISDI--CDENCDY 418
           + G  +   FS   +               H   ++    +     A  D+   + +   
Sbjct: 347 NTGEVMAELFSGGSDSSHPHSSALAQVSALHINAQQVSRFLHTYSAATQDLQVKELHRLQ 406

Query: 419 SDKFIKSALKKWFL----TVQSELIGSASEVPNKSLGVCVFLLLV 459
           +     SA  + FL      ++ L    +E      G    L + 
Sbjct: 407 TLFSKASARYQHFLRDPQEAEAALSTLTAEFQQFLRG-ARALCIE 450
 Score = 63.3 bits (153), Expect = 1e-08
 Identities = 11/50 (22%), Positives = 21/50 (42%), Gaps = 3/50 (6%)

Query: 742  SLLNHLFSYRISS---MCTSLICLYIFQNHLFIWSVYSPKVVYDMAHVIF 788
            +LL     Y       +    +   I + HL +W V++PK +++    I 
Sbjct: 1020 ALLQLGLKYLFILGAQILACALAASILRRHLMVWKVFAPKFIFEAVGFIV 1069
 Score = 62.5 bits (151), Expect = 2e-08
 Identities = 25/128 (19%), Positives = 43/128 (33%), Gaps = 12/128 (9%)

Query: 625 IRLSILP-----ISYSTGSVLAGCLPLLLAIVPVSQILLLLVIYNMGKLFSKLNLGSVEF 679
           + L   P     +   +   L   L   L +  ++    +         F+ L      +
Sbjct: 849 LLLLAFPLMLLHVERVSLVFLLLFLQSFLLLHLLAAGTPVATPG----PFTVLWQAVSAW 904

Query: 680 VTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQ---PILVGLQLMLYTFSGPILFLCGCN 736
           V L   +F+ TG+    S +   +A+VG          L  L +   TF+  +LF  GC 
Sbjct: 905 VLLATQTFYSTGHQPVFSAIHWHAAFVGFPDGHGSSTWLPALLVGANTFASHLLFAVGCP 964

Query: 737 ASSCTSLL 744
                  L
Sbjct: 965 LLLLWPFL 972
>ref|NP_491750.1| (NM_059349) C27A12.9.p [Caenorhabditis elegans]
 gb|AAB93646.1| (AF003137) Hypothetical protein C27A12.9 [Caenorhabditis elegans]
          Length = 905

 Score =  348 bits (886), Expect = 1e-94
 Identities = 94/430 (21%), Positives = 161/430 (36%), Gaps = 65/430 (15%)

Query: 57  KFWISRVLVVCACALLVY--SFVA-LDITPTPPTEEFGFKDG---NQESSSSPRLVFMVI 110
              I  V +    AL ++   F+       +  +                   R++ +++
Sbjct: 4   IIRILLVSINILLALFIFQNGFLLKRQEILSKSSCSDAHAQPGQTCWMKQQYQRVILILV 63

Query: 111 DAFRLSFLTSSKSP-------------MSFTKSEITKKSAKLFDAYARMPTVTLPRITAY 157
           DA R  FL                   M   +  +   +  +    A  PT TL R+ A 
Sbjct: 64  DALRYDFLIPIDENTKKSKEEWYYRGQMKNIEKLVKSGNVSIGTLLADPPTTTLQRLKAL 123

Query: 158 LTGTLPSFGTVLTNLATAE-MKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVT 216
            TGTLP+F     N +    +   +++ +  ++GK V   GDDTW+ L P  F K     
Sbjct: 124 TTGTLPTFIDAGDNFSPDAVISEDSFVYQAAQLGKNVTLLGDDTWLSLFPNQFSKTAAYD 183

Query: 217 SFFVSDYTDVDNNVTRHLD--------------TELSNT--NHSWDALILHYLGLDHIGH 260
           SF ++D   VD+ + R +                 L +   N +   +I H+LG+DH GH
Sbjct: 184 SFDINDLNTVDDKIARKIFFGKYYNKMVFCFEGPILQDEMLNSNSSIIIAHFLGVDHCGH 243

Query: 261 SLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDE 320
             G S   + + L++MD +IG+  + +KS              DHGMT+ G HGG S +E
Sbjct: 244 KFGPSHPVMADTLRKMDRIIGQTIETMKSD-------------DHGMTSTGDHGGESENE 290

Query: 321 TRVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLIN 380
            R  +++     +            +     I QID+  TI  +  +PIP  + G  +  
Sbjct: 291 IRAGILVHSKKHQI-----------ILPERPIHQIDIVPTISLLMGLPIPFSNLGTVITQ 339

Query: 381 YFSDDEEEYFEKQHNQFRR----IVQAKHLAISDICDENCDY-SDKFIKSALKKWFLTVQ 435
            F+ D  E   +      +    I    + A  +  + +     D             +Q
Sbjct: 340 LFTRDLWEIARQMMGFVWQDSVGIFAETYAAQKNFGELHSHTIRDSNTMEEQLDTMSRIQ 399

Query: 436 SELIGSASEV 445
           + L  S ++ 
Sbjct: 400 TLLRVSWTQF 409
 Score = 80.5 bits (197), Expect = 1e-13
 Identities = 28/163 (17%), Positives = 69/163 (42%), Gaps = 16/163 (9%)

Query: 643 CLPLLLAIVPVSQILLLLVIY----NMGKLFSKLNLGSVEFVTLCMSSFFYTGNSNSLST 698
            L + + I+    ++  ++I+     +   F      +     L    F++ G+S  +S+
Sbjct: 714 FLLMPVYILFGDGLIPAIIIFIAVSVLIAEFVSREFIASTIALLIPLGFYHLGHSPVISS 773

Query: 699 LSLTSAYVGLSSYQ--PILVGLQLMLYTFSGPI--LFLCGCNASSCTSLLNHLFSY---- 750
           +   +A+VG+       +L  L ++ +     I  +F+    + S   +     ++    
Sbjct: 774 IPWNAAFVGIPGGTALRVLPALFVLFHLNFSAISSIFVISSESESSQKMSAPNTAWTLTE 833

Query: 751 --RISSMCTSLICL--YIFQNHLFIWSVYSPKVVYDMAHVIFF 789
              + ++  +L CL   I + HL +W +++PK +++    I F
Sbjct: 834 TLVLMTIRATLTCLVSSIHRRHLMVWKIFAPKFIFECILTIVF 876
>gb|AAF56048.1| (AE003740) CG4907 gene product [Drosophila melanogaster]
          Length = 919

 Score =  348 bits (886), Expect = 2e-94
 Identities = 69/452 (15%), Positives = 140/452 (30%), Gaps = 42/452 (9%)

Query: 59  WISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRL-SF 117
           W  + LVV    L     +    T     E             + RLV  V+D  R  S 
Sbjct: 2   WSIQALVVHLLLLGSILSIYFQSTILSDLEPLSTLRELGLEPPADRLVVFVVDGLRAQSV 61

Query: 118 LTSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM 177
           L    S +   +    ++ A +  + A  PTVT P   A        FG    + A    
Sbjct: 62  LADHCSAVPDLRELFVEQ-ALVGISRACPPTVTRPGHIAI-------FGGFNEDPAATLT 113

Query: 178 KTAN-WISRIQKIGKKVHFFGDDTWIRLLPRSFE-----KFEGVTSFFVSDYTDVDNNVT 231
              + + S   +    + +       ++           +FE      +SD   +D    
Sbjct: 114 WNPSTFDSVFNRSRNAIGWM-QAEVAKVFTHLPTGGAPLRFETFARSDISDRLRLDQWTF 172

Query: 232 RHLDTELSNT-------NHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIH 284
             +   ++N        + +     ++   +D   H    +S    EKL      I + +
Sbjct: 173 DKVRNFMTNEQNVQPLRDATSVIFFVYLADIDLAEHVHMPNSLNFREKLNYTQRGIRQTY 232

Query: 285 KYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQ-- 342
           +  +S    D  +  ++  D+G++    HGG        P ++W  G +    N G    
Sbjct: 233 ELFES-VFNDSRTAYLMTADYGISL---HGGGGERGVETPFILWGAGVKRSAPNPGQNFT 288

Query: 343 ---DDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEEYFEKQHNQFRR 399
              +  +    ++EQI ++  +  +  +P P+ +  +  + + +   +   +  H    +
Sbjct: 289 AGENGPILPLYQLEQIQLAPLMSALIGLPPPMNNMALMPLGFLNTSVQYELQVLHLNAMQ 348

Query: 400 IVQAKHLAISDICDE--NCDYSDKFIK-SALKKWFLTVQSELIGSA-SEVPNKSLGVCVF 455
           ++    + I    D              SA  + +  +   L+     E   K       
Sbjct: 349 LLAQARILIKRHEDGILYLLLPKFESLGSAEIENYPQIIKYLVAKEQYEEALKVSHKIAK 408

Query: 456 LLLVALTLSMGLWNLHLSKSDFFIFLINITYF 487
           L          +   H       +     +Y 
Sbjct: 409 LAQEC------MEYYHGYYHLPLLVATTASYL 434
>pir||T40030 hypothetical protein SPBC27B12.06 - fission yeast
           (Schizosaccharomyces pombe)
 dbj|BAA21454.1| (AB004539) ORF YLL031c [Schizosaccharomyces pombe]
 emb|CAA16901.1| (AL021766) hypothetical protein [Schizosaccharomyces pombe]
          Length = 918

 Score =  342 bits (869), Expect = 1e-92
 Identities = 113/459 (24%), Positives = 179/459 (38%), Gaps = 59/459 (12%)

Query: 51  MISKKGKFW-ISRVLVVCACALLVYSFVALDIT---------PTPPTEEFGFKDGNQESS 100
              +   F+ I  +            F+              P     E+    G     
Sbjct: 20  KYIQACIFFAIILISNFYGLKSFTDGFLLRRAVLNQTSLCENPPADVREWKNSSGCWAPK 79

Query: 101 SSPRLVFMVIDAFRLSFLTSSKSP--------MSFTKSEITKKSAKLFDAYARMPTVTLP 152
              R V ++IDA R  FL                +  S +  +++ L    A  PT T  
Sbjct: 80  IFERAVIVIIDALRYDFLIPYNDSNYYHNAFTTPYETSVLHPENSYLTQFIADAPTTTSQ 139

Query: 153 RITAYLTGTLPSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEK- 211
           R+    TG+LP+F  + +N A   +   N + + + + K++   GDDTW  L      + 
Sbjct: 140 RLKGLTTGSLPTFIDLGSNFAGTNIDEDNLLLQWKSLDKQIVLLGDDTWDVLFHDYLNET 199

Query: 212 -FEGVTSFFVSDYTDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIP 270
             +   SF V D   VDN V +++   +   + ++D LI HYLG+DH+GH LG     + 
Sbjct: 200 LSQPAFSFNVPDLHGVDNKVNQYVFDYI--KDANFDVLIAHYLGVDHVGHRLGPDHPTMR 257

Query: 271 EKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKF 330
           +KL +MD  +  +   L      D  + LIV GDHGM   G+HGG S DE     V+W +
Sbjct: 258 DKLNQMDRCVKEMMDLL------DDSTLLIVMGDHGMDNKGNHGGDSFDEINS--VLWMY 309

Query: 331 GREEGNKNYGNQDDSLKQPPRI---EQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEE 387
            ++            LKQP ++    Q+D+  T+  +   PIP  + G  +   F    +
Sbjct: 310 SKKPTF-------GYLKQPGKVLSANQVDLVPTLSLLLGNPIPYGNLGTLIPEPFYYYGD 362

Query: 388 EYFEKQH----NQFRRIVQAKHLAISDICDENCDYSDKFIKSALKKWFLTVQ------SE 437
           EY  K       Q  R      L  SD    +   ++    S L ++FL         S 
Sbjct: 363 EYLSKAQKINIGQLNRFFSEYDLDASDFLSSSVHKNN---NSYLDQYFLDFDYARDAFSY 419

Query: 438 LIGSASEVPNKSLGVCVFLLLVALTLSMGLWNLHLSKSD 476
                +E     + +   LL+      +G +NL L   D
Sbjct: 420 FKAIWAEFSLFPMIIGFLLLI------IGGFNLALLMQD 452
 Score =  266 bits (675), Expect = 8e-70
 Identities = 59/387 (15%), Positives = 120/387 (30%), Gaps = 69/387 (17%)

Query: 473 SKSDFFIFLINITYFASSLIEEEHEIWYYLGSTVVAI---RALRN----FKIWNKTEVKS 525
             S F  FL   ++ ++S    E  + ++L  T+  +   +        F     + +  
Sbjct: 522 YFSIFITFLHVCSFGSNSFTVWEDRLCHFLIITIGLVMFCKCFSEMSPLFACSTYSALAF 581

Query: 526 IFFLAFLHRIACSYTQSTRRR-WIMD--SSLLPPSIFSDTLDFQPNNLNTILNEY----- 577
           I        +    T     +           P +     +      L++I+        
Sbjct: 582 ILLQVISSYV----TNCREEQGAFCVSTYISTPDNSLRTLIVLALMALSSIILPLILQLH 637

Query: 578 ----------------PIIVILTCSLFWMYGYKQSKFHIILPMVSHFLRLFELTQFNEVL 621
                                L  S+FW+  +  +   ++     H L     T    +L
Sbjct: 638 LRRVLGLSLKLYHLSILYFFELISSIFWIAHHVFANDALLEKQYHHVLYSLANTYVICIL 697

Query: 622 MHFIRLSILPISYSTGSVLA-------GCLPLLLAIVPVSQILLLLVIY----------- 663
              +      +S S  + +            L   +  + + L  L ++           
Sbjct: 698 GV-LIWQFFLLSRSKFAKINVIERSYFVFALLYSFLSFLQRPLGHLSLFSCFLQILLLIQ 756

Query: 664 -NMGKLFSKLNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAY-VGLSSYQPILVGLQLM 721
               +     N  SV    L +S FF TGN  ++S+L    A+    S+    +  + + 
Sbjct: 757 LKQWQPSVGHNFFSVTLGLLGLSHFFTTGNQAAISSLDWNFAFIHSKSAENQAISAIFMF 816

Query: 722 LYTFSGPILFLCGCNASSCTSLLNHL----------FSYRISSMCTSLICLY---IFQNH 768
           L+T   PIL        S   L              FS+ + ++  S   ++    F+ H
Sbjct: 817 LHTVGAPILTCISIPLFSFEPLSKKNRFLINLFRFSFSFILYNLLISTSTVFFAGFFRRH 876

Query: 769 LFIWSVYSPKVVYDMAHVIFFGLIGLL 795
           L +W V++P+ +     ++   L  L+
Sbjct: 877 LMVWKVFAPRFMLSGILLVTHQLFVLI 903
>ref|NP_179839.1| (NM_127819) unknown protein [Arabidopsis thaliana]
 gb|AAF18652.1| (AC006592) unknown protein [Arabidopsis thaliana]
          Length = 897

 Score =  340 bits (865), Expect = 5e-92
 Identities = 104/361 (28%), Positives = 174/361 (47%), Gaps = 31/361 (8%)

Query: 63  VLVVCACALLVYSFVALDITPTPPTEE--------FGFKDGNQESSSSP---RLVFMVID 111
           +L +   ++ V+ F  +  T +  +                N+     P   RL++ VID
Sbjct: 20  LLQIIGLSIFVFGFFPVKPTLSGVSGSESYRDPFCDSSLISNESELHHPEKLRLLYQVID 79

Query: 112 AFRLSFLTSSK---------SPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTL 162
                F+               M +T+S +    A  + A A  PTVT+PR+ A ++G +
Sbjct: 80  GLPAEFVLGKDGKPPEKVLKESMPYTQSLLANGDAIGYHAKAAPPTVTMPRLKAMVSGAI 139

Query: 163 PSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSD 222
             F  V  N  T  +   N + +  +IG K+   GD+TW++L P  F + +GV+SFFV D
Sbjct: 140 GGFLDVAFNFNTQALLDDNILGQFFRIGWKMVMLGDETWLKLFPGLFMRHDGVSSFFVKD 199

Query: 223 YTDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGR 282
              VD NV+RHL  EL++ +  W+ LILHYLGLDH+GH+ G +S  +P KLKEMDD++  
Sbjct: 200 TVQVDRNVSRHLPDELNSDD--WNLLILHYLGLDHVGHTGGRNSPLMPAKLKEMDDIVRT 257

Query: 283 IHKY-LKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGN 341
           +H   +   +    ++ LI+  DHGMT  G+HGG+S +ET   ++         +     
Sbjct: 258 MHLRAMMDRSHDQGQTLLIIVSDHGMTENGNHGGSSYEETDSLMLFIGLNSNISDYASAT 317

Query: 342 QDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEE-EYFEKQHNQFRRI 400
            + +        Q+D++ T+  +F +PIP  + G+ +        + E          ++
Sbjct: 318 NNVAF-------QVDLAPTLALLFGVPIPKNNVGVLVPGTLCSLRDFEQLRALELNSWQL 370

Query: 401 V 401
           +
Sbjct: 371 L 371
 Score =  231 bits (586), Expect = 2e-59
 Identities = 74/430 (17%), Positives = 148/430 (34%), Gaps = 84/430 (19%)

Query: 383 SDDEEEYFEKQHNQF---RRIVQAKHLAISDICDENCDYSDKFIKS--ALKKWFLTVQSE 437
           S D+E+              I ++K    S          + F ++  A   +  T    
Sbjct: 407 SGDKEKQLICLFRNAAALHGIWKSKKSTESS------STMEDFSRALDAYNTFLKTASEW 460

Query: 438 LIGSASEVP--NKSLGVCVFL--LLVALTLSMGLW---------------NLHLSKSDFF 478
           L    +E P     LGV   L    +  T+ + L+               NL   +  F 
Sbjct: 461 LASKTTEKPVLLLGLGVSAMLLSCFICGTVFLSLFKEVYHEPKDRVCSLSNLLNLEEVFI 520

Query: 479 ---IFLINITYFASSLIEEEHEIWYYLGSTVVAIRALRN-FKIWNKTEVK--------SI 526
              + ++ I+  +SS++EEEH IW+++ ST   +   +          +         SI
Sbjct: 521 FALLLILVISMGSSSMVEEEHYIWHFMVSTFHLLLLFKTAKSFKISKGMNILRDFKFGSI 580

Query: 527 FFLAFLHRIACSYTQSTRRRWIMDSSLLPPSIFSDTLDFQPNNLNTILN---EYPIIVIL 583
           F L    R+   + Q       +                    ++ IL        +   
Sbjct: 581 FSLLISGRLLRGWHQGGVNWTYLPDISKWLVQGGSGYVKWIQLISIILVIGLGLYTLFRT 640

Query: 584 TCS----LFWMYGYKQSKFHIIL-------PMVSHFLRLFELTQFNEVLMHFIRLSILPI 632
             +        +G+    F ++L        + + F     +     +L      + L +
Sbjct: 641 GSNRKGVRILAFGFSTCGFLVLLHVGRYQDELSTGFGATVTVKVIYYLLSISSIGASLVL 700

Query: 633 SYSTGSVLAGCLPLL---LAIVPVSQILLLLVIYNMGKLFS--------------KLNLG 675
            +S  +     L  +   L ++  + IL   ++  + +                  L L 
Sbjct: 701 PWSALNKDKSFLAEVGDCLYLIGSAYILCWCLLQQLLQQPINSGPILLLLLQILAILCLS 760

Query: 676 SVEFV---TLCMSSFFYT--------GNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYT 724
           S +F     + +++ +Y         GNSN+L+T+ +  A++G+SS+  IL G+ + + T
Sbjct: 761 SSDFQVNEWVEITALYYMGMAGHFALGNSNTLATIDVAGAFIGISSHSTILSGILMFMIT 820

Query: 725 FSGPILFLCG 734
           ++ P+LFL  
Sbjct: 821 YASPMLFLLS 830
>gb|AAF57689.1| (AE003799) CG12263 gene product [Drosophila melanogaster]
          Length = 1077

 Score =  334 bits (849), Expect = 3e-90
 Identities = 94/385 (24%), Positives = 158/385 (40%), Gaps = 53/385 (13%)

Query: 58  FWISRVLVVC--ACALLVYSFVALDITPTPPTE-----------------------EFGF 92
           F +  +  +      L    F+   ++ T  +                        +   
Sbjct: 7   FVLIWLAFLISSGVMLFSRGFLLARVSKTETSTCRRLSTNPNAEYVLTDEVVNEIFKDVN 66

Query: 93  KDGNQESSSSPRLVFMVIDAFRLSF---LTSSKSPMSFTKSEI--------TKKSAKLFD 141
              N       +++ +V+DA +  F     ++  P+ +    +            A+L  
Sbjct: 67  ASSNLCLPQKSKVIVLVVDALKYEFGLYRANATDPLPYENKLVVLQELLQQNPDHARLMR 126

Query: 142 AYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTW 201
             A  PT TL R+    TG+LP+F  + +N A+ E+   N I +I K    V F GD TW
Sbjct: 127 FRADPPTTTLQRLKGLTTGSLPTFIDIGSNFASPEINEDNIIDQIVKNDLPVVFLGDSTW 186

Query: 202 IRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHS 261
             L P  F++     SF + D   VDN + +HL  EL + +  W  L+ H+LG+DH GH 
Sbjct: 187 TDLYPHRFKRSYSYPSFDIFDLDSVDNEILKHLPKELESKD--WQVLVAHFLGVDHCGHK 244

Query: 262 LGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDET 321
            G    ++  KL EM++VI  +   +      D ++ L+V GDHGMTA+G HGG + DET
Sbjct: 245 HGPMHEEMARKLGEMNEVIRSVVAAM------DNDTTLLVMGDHGMTASGDHGGDTDDET 298

Query: 322 RVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGIS---L 378
              +  +              +DS      ++QID+  T+  +  +PIP  + G+    +
Sbjct: 299 NALLFAYSKQHRFYG------NDSGSDSEMLQQIDLVPTLATILGVPIPYSNLGLVNFNI 352

Query: 379 INYFSDDEEEYFEKQHNQFRRIVQA 403
           +          F+       +  Q 
Sbjct: 353 VPDLRVPHLNKFQTLLLHSWQNAQQ 377
 Score =  182 bits (459), Expect = 2e-44
 Identities = 39/205 (19%), Positives = 77/205 (37%), Gaps = 14/205 (6%)

Query: 547 WIMDSSLLPPSIFSDTLDFQPNNLNTILNEYPIIVILTCSLFWMYGYKQSKFHIILPMVS 606
            I+  S  P    +  L  + ++  TI     I+  +   +  MY     +    +P+V 
Sbjct: 746 QIIVLSWAPL--MTFVLPPRSSHTVTINGNESIVPEIFRKMKRMYEGDDDERRSHIPVVY 803

Query: 607 HFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIVPVSQILLLLVIYNMG 666
               ++        +   + + +L    ++   L  C+ +   ++ V  IL     Y   
Sbjct: 804 GLATVYSSIVIAFGVFLALVMIVLLEPRASIG-LVVCVAVGAILLSVHSILR----YRTA 858

Query: 667 KLF---SKLNL-GSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSS---YQPILVGLQ 719
             F    +      V +  L    FF T +  +LS +   +A+VG ++      ++ G  
Sbjct: 859 TSFESCVQPTFTALVGWFLLAHFCFFATSHQTTLSQIEWRAAFVGRTTGIGQSNLVSGAL 918

Query: 720 LMLYTFSGPILFLCGCNASSCTSLL 744
           ++L TF GPI F C  +  S  +  
Sbjct: 919 VILNTFCGPIFFFCMYSLLSTETFS 943
 Score = 53.2 bits (127), Expect = 2e-05
 Identities = 9/33 (27%), Positives = 16/33 (48%), Gaps = 1/33 (3%)

Query: 756  CTSLICLYIFQNHLFIWSVYSPKVVYDMAHVIF 788
            C  L C  I   HL +W +++P+ +Y+      
Sbjct: 1014 CAMLAC-TIHCRHLMVWKIFAPRFIYEALATFV 1045
>ref|NP_197227.1| (NM_121731) unknown protein [Arabidopsis thaliana]
 dbj|BAB10512.1| (AB005238) gene_id:MKP11.10~unknown protein [Arabidopsis thaliana]
          Length = 884

 Score =  331 bits (841), Expect = 3e-89
 Identities = 96/498 (19%), Positives = 168/498 (33%), Gaps = 97/498 (19%)

Query: 382 FSDDEEEYFEKQHNQFRRIVQAKHLAISDICDENCDYSDKFIKSALKKWFLTVQSELIGS 441
           FS D+       ++   +        I  + D N D     I + LK     +   L   
Sbjct: 394 FSSDDMSRISDLYSAAEQNWSNSVKHI--LMDRNGDDGSTDISALLK---EQIAEYLNFF 448

Query: 442 ASEVPN---------KSLGVCVFLLLVALTLSMGLWNLHLSKS--------------DFF 478
           +S V            +L +  F +LV   +   L   H  KS               F 
Sbjct: 449 SSVVELARSKWTEFNLNLMITGFGILVISLILQFLAVFHGDKSYAVGSWLSTGAAFTLFI 508

Query: 479 IFLINITYFASSLIEEEHEIWYYLGSTVVAIRALRNFKIWNKTEVKSIFF-LAFLHR--I 535
           + +   ++ ++S I EE ++  +L +T   I+   +       +   +F  + F+ R  I
Sbjct: 509 VTIRACSFLSNSYILEEGKVANFLLATTGLIKLRYSVMRKTMRKEAFMFLAMVFVLRVSI 568

Query: 536 ACSYTQSTRRRWIMDSSLLPPSIFSDTLDFQPNNLNTI-LNEYPIIVILTCSL------- 587
               T+       M SS   PS         P     I +     +VIL C L       
Sbjct: 569 DIGLTKQAATSQFMSSS---PSWMLGIAPDHPALTYAIEIAPILSVVILICVLYVAIAKA 625

Query: 588 ----FWMYGYKQSKFHIILPMVSHFLRLFELTQFNEVLMHFIRLS--------------- 628
                W Y    S   ++L +     R+ +      ++   +  S               
Sbjct: 626 PNEGVWKYVTVGS---MLLQVTGGRNRIPQTVYVIGLVQLCLLASARMFCTEKDKNWAIR 682

Query: 629 --------ILPISYSTGSVLAGCLPLLLAIVPVSQILLLLVIYNMGKL-----FSKLN-L 674
                     PI   +G    G +  L+ +V    I+ L  +    K      FSKLN L
Sbjct: 683 TVALVSACSSPIILLSGKQ--GSMLALVYLVAGYCIMRLEGVERRTKSDGQSKFSKLNPL 740

Query: 675 GSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLYTFSGPILFLCG 734
             V++  L +  FF +G+  +   L   +A+VG   +  I   + L + TF   I+    
Sbjct: 741 CVVQWSLLSICMFFASGHWCAFDGLRYGAAFVGFDEFVLIRQAILLTIETFGFSIILSVF 800

Query: 735 CNASSCTSLLN----------HLFS-YRISS------MCTSLICLYIFQNHLFIWSVYSP 777
                                 LF  Y +        +  +++C+ I + HL +W +++P
Sbjct: 801 GLPLLIPFHSQTPQAHGEKRHQLFQMYMLFGVISATTVTATILCVTIQRRHLMVWGLFAP 860

Query: 778 KVVYDMAHVIFFGLIGLL 795
           K V+D+  +I   L+  L
Sbjct: 861 KFVFDVVDLILTDLLICL 878
 Score =  283 bits (719), Expect = 7e-75
 Identities = 82/303 (27%), Positives = 123/303 (40%), Gaps = 22/303 (7%)

Query: 61  SRVLVVCACALLVYSFVA-LDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLT 119
             ++   A  +    F+      P   T           S  S                +
Sbjct: 15  FLLIHAIAILIFTRGFLLTRTELPFHSTCSDVSLSPCLASPRSN-----------HDSSS 63

Query: 120 SSKSPMSFTK-----SEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLAT 174
             K  M         +     SAK+F A+A  PT +L R+    TG LP+F  +  +   
Sbjct: 64  EPKPWMDKLTILQTLAFANDSSAKIFKAFADPPTTSLQRLKGLTTGGLPTFIDIGNSFGA 123

Query: 175 AEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHL 234
             +   N+I+++   GK++   GDDTW +L P  F+K     SF V D   VDN    HL
Sbjct: 124 PAIVEDNFINQLVLNGKRLVMMGDDTWTQLFPNQFQKSYPFPSFNVKDLDTVDNGCIEHL 183

Query: 235 DTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSS---T 291
              L   +  WD LI H+LG+DH GH  G  SS +  KL++ + V+ ++   L+S     
Sbjct: 184 FPTLFKDD--WDVLIAHFLGVDHAGHIFGVDSSPMINKLEQYNSVLEKVINILESQAGPG 241

Query: 292 SVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQDDSLKQPPR 351
            + + + LIV GDHG T  G HGG + +E    +      +            S KQ   
Sbjct: 242 GLHENTMLIVMGDHGQTLNGDHGGGTAEEVETTMFAMSTKKHTTLVPPEFDTSSCKQNKD 301

Query: 352 IEQ 354
            +Q
Sbjct: 302 GKQ 304
>dbj|BAB29186.1| (AK014165) data source:MGD, source key:MGI:1351629,
           evidence:ISS~phosphatidylinositol glycan, class
           N~putative [Mus musculus]
          Length = 320

 Score =  321 bits (816), Expect = 3e-86
 Identities = 64/311 (20%), Positives = 99/311 (31%), Gaps = 30/311 (9%)

Query: 63  VLVVCACALLVYSFV--ALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
           +L      L+ + F     DI  T P               + RLV  V D  R   L  
Sbjct: 2   LLFFALGLLIHFVFFASIFDIYFTSPLVHGMTPQFTPLPPPAKRLVLFVADGLRADTLYE 61

Query: 121 SKSPMSFTKSEITK---KSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM 177
                +     I            ++ R+PT + P   A + G       V        +
Sbjct: 62  LDEDGNSRAPFIRNVIMHEGSWGVSHTRVPTESRPGHVALIAGFYEDVSAVAKGWKENPV 121

Query: 178 KTANWISRIQKIGKKVHFFGDD-TWIRLL------PRSFEKFEGV--TSFFVSDYTDVDN 228
           ++ +  +      +K  +       + +          +          F   D T +D 
Sbjct: 122 ESDSLFNE-----RKYTWSWGSPDILPMFAKGASGDHVYTYSYDAQREDFGAHDATKLDT 176

Query: 229 NVTRHLDTELS----------NTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDD 278
            V   +                 N       LH LG+D  GH+   SS +  + +K++DD
Sbjct: 177 WVFDKVKDFFDAARNNQSLFTKVNEEKVVFFLHLLGIDTNGHAHRPSSREYKDNIKKVDD 236

Query: 279 VIGRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEG-NK 337
            +  I    K     D ++  I   DHGMT  GSHG   P ET  P V W  G +   N 
Sbjct: 237 GVKEIVSIFKHFYGDDGKTAFIFTSDHGMTDWGSHGAGHPSETLTPFVTWGAGIKFPQNV 296

Query: 338 NYGNQDDSLKQ 348
           +    DD   +
Sbjct: 297 SAQQYDDEFLK 307
>gb|AAF59237.1| (AE003840) CG2144 gene product [Drosophila melanogaster]
          Length = 880

 Score =  310 bits (788), Expect = 5e-83
 Identities = 104/395 (26%), Positives = 174/395 (43%), Gaps = 47/395 (11%)

Query: 55  KGKFWIS-----RVLVVCACALLVYSFVALDITPT---PPTEEFGFKDGNQESSSSPR-- 104
           + K W+          +C   L +  F     +         E           + P   
Sbjct: 3   QHKSWLVYTIGMLTAFLCGAVLFLIGFFPASYSVAEKESTVPEGRPTALLGMELTPPPPA 62

Query: 105 ---LVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGT 161
               V +++DA R  F  ++  P++++++            +  +PTVT+PR+ +  TGT
Sbjct: 63  YDSFVLLLVDALRDDFPDATSMPVAYSRACE------KLKLHVDIPTVTMPRLKSITTGT 116

Query: 162 LPSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKF-EGVTSFFV 220
           L +F  +  N+   E    +++ R+++  + V F GD TW++L P  F +  E   SF+V
Sbjct: 117 LSNFIDIALNVGHTEQMQDSFLHRLKQQNRVVSFAGDHTWVKLFPSEFTRQVENHDSFYV 176

Query: 221 SDYTDVDNNVTRHLDTELSNTNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVI 280
           +D+ + D NVT+ L+TEL  ++  W  LILHYLGLDHIGH  G +S ++P KLKEMD+V+
Sbjct: 177 NDFYEGDRNVTKTLETELERSD--WSLLILHYLGLDHIGHVEGNASPRVPLKLKEMDEVV 234

Query: 281 GRIHKYLKSSTSVDQESYLIVCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYG 340
            +I   L   +       L++ GDHGM   G HGG +P ET VP+ ++          Y 
Sbjct: 235 KKI---LDHKSFP--NVLLMLTGDHGMADGGGHGGNTPAETLVPLYLY----------YN 279

Query: 341 NQDDSLKQPPRIEQIDVSSTIFDVFNMPIPIESYGISLINYFSDDEEE-YFEKQHNQFRR 399
           N   +     R  QID++ T+  + ++ IP  S G  +         E            
Sbjct: 280 NCSKTPSASKRYNQIDLAPTLSVLLSVEIPTLSIGCLIPEMLQSLSLEHQLYAYFYNAHH 339

Query: 400 IVQAKHLAISDICDENCDYSDKFIKSALKKWFLTV 434
           ++    +             +   +S    W+   
Sbjct: 340 LLNKARVK-------FGH--EIVHRSDYYTWYQNA 365
 Score =  208 bits (527), Expect = 2e-52
 Identities = 70/337 (20%), Positives = 125/337 (36%), Gaps = 50/337 (14%)

Query: 498 IWYYLGSTVVAIRALRNFKIWNKTEVKS-----IFFLAFLHRIACSYTQSTRRRW----- 547
              +    V+ +  L     +            IF +  L   A    + ++        
Sbjct: 543 TCLWQMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLL--WAR-LHRHSQLPQSLASG 599

Query: 548 ---IMDSSLLPPSIFSDTLDFQPNNLNT-ILNEYPIIVILTCSLFWMYGYKQSKFHIILP 603
               M       +         P+++   ++    +I     +L  M GY+ +     LP
Sbjct: 600 AALFMVYCFRGLNG-QVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAA-----LP 653

Query: 604 MVSHFLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIVPVSQILLLLVIY 663
               F ++        + +    L+   +  +    +   L L + +V + Q   L  +Y
Sbjct: 654 QAHSFGKVPPT--GALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVY 711

Query: 664 --NMGKLFSK--LNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQ 719
             +  K   +       +  + L    FFY GNSNSLST+ LT  Y+G ++Y P +V + 
Sbjct: 712 GTSARKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIF 771

Query: 720 LMLYTFSGPILFLC------------------GCNASSCTS--LLNHLFSYRISSMCTSL 759
           + L T+S  I                           S  +  L+  L++  I       
Sbjct: 772 VTLNTYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFY 831

Query: 760 ICLYI-FQNHLFIWSVYSPKVVYDMAHVIFFGLIGLL 795
           +CL + F+ HLFI+SV+SPKV+YD   V+ F L+ L+
Sbjct: 832 LCLLVGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLV 868
>dbj|BAB20681.1| (AB032413) nucleotide pyrophosphatase-like protein [Spinacia
           oleracea]
          Length = 479

 Score =  290 bits (736), Expect = 6e-77
 Identities = 50/323 (15%), Positives = 104/323 (31%), Gaps = 43/323 (13%)

Query: 12  ERKWLDCEEAEEEDTKRKSIKFLRTHNHHQSENKELQELMISKKGKFWISRVL---VVCA 68
           E   L        ++K   + F      H   +        + + K  +  +L       
Sbjct: 2   ESDPLHSPAHHHPNSKTALLSF------HTDSSITTSAAKPTFQNKVLLISLLSTTFTAV 55

Query: 69  CALLVYSFVALDITPTPPTEE----FGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSP 124
            A + ++F+ L  T     E           +    + P ++ +  D FR  +   +  P
Sbjct: 56  IAAVSFAFLFLSATSAAAGESKTIKITTTARSLTKLTHPIVILISSDGFRFGYQFKA--P 113

Query: 125 MSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM------- 177
                  I   ++         PT+T P   + +TG  P    ++ N     +       
Sbjct: 114 TPNIHRLINNGTSAELGLIPVFPTLTFPNHYSIVTGLYPPHHGIINNYFVDPITGDKFSM 173

Query: 178 ---------KTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDN 228
                        W +  +   K   +F   +   ++   ++              +   
Sbjct: 174 ASHEPKWWLGEPLWETVAKHGKKAATYFWPGS--EVIKPDWDCPSNYCIH-----YNGSI 226

Query: 229 NVTRHLDTELSNTN----HSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIH 284
                +DT +S  +         + L++   DH GH +G    +I + +  +D +IGR+ 
Sbjct: 227 PFEERVDTVISYFDLPINEIPVFMTLYFEDPDHQGHQVGPDDPEITQAVINIDKMIGRLI 286

Query: 285 KYLKSSTSVDQESYLIVCGDHGM 307
           K L+     + +  + + GDHGM
Sbjct: 287 KGLEKRGVFE-DVNIFMVGDHGM 308
>ref|NP_194697.1| (NM_119113) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09931 nucleotide pyrophosphatase homolog T16L4.190 - Arabidopsis thaliana
 emb|CAB45328.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79726.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 496

 Score =  275 bits (699), Expect = 1e-72
 Identities = 57/327 (17%), Positives = 111/327 (33%), Gaps = 43/327 (13%)

Query: 11  SERKWLDCEEAEEEDTKRKSIKFLRTHNHHQSENKELQELMISKKGKFWISRVLVVCACA 70
           S +K     + E++D   +SI  L   ++H   +              + S +LV C   
Sbjct: 8   SAKKPKSVPQEEDQDPPSQSIALL---DNHTDSSGSDSSTRSISSCFIFTSLLLVTCIAL 64

Query: 71  LLVYSFVALDITPTPPTEE----------FGFKDGNQESSSSPRLVFMVIDAFRLSFLTS 120
               +F  L  +   P                     +    P ++ +  D FR  +   
Sbjct: 65  SAASAFAFLFFSSQKPVLSLNQISKSPAFDRSVARPLKKLDKPVVLLISSDGFRFGYQFK 124

Query: 121 SKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAE---- 176
           +K  +      I   +          PT+T P   + +TG  P++  ++ N         
Sbjct: 125 TK--LPSIHRLIANGTEAETGLIPVFPTLTFPNHYSIVTGLYPAYHGIINNHFVDPETGN 182

Query: 177 ------------MKTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYT 224
                       +    W + + +  K   +F   +   +   S+   +G+         
Sbjct: 183 VFTMASHEPEWWLGEPLWETVVNQGLKAATYFWPGS--EVHKGSWNCPQGLC-----QNY 235

Query: 225 DVDNNVTRHLDTELSNTN----HSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVI 280
           +        +DT LS  +         + L++   DH GH +G    +I E +  +D +I
Sbjct: 236 NGSVPFDDRVDTILSYFDLPSNEIPSFMTLYFEDPDHQGHQVGPDDPQITEAVVNIDRLI 295

Query: 281 GRIHKYLKSSTSVDQESYLIVCGDHGM 307
           GR+   L+     +  + ++V GDHGM
Sbjct: 296 GRLIDGLEKRGIFEDVTMIMV-GDHGM 321
>ref|NP_194698.1| (NM_119114) nucleotide pyrophosphatase - like protein [Arabidopsis
           thaliana]
 pir||T09932 nucleotide pyrophosphatase homolog T16L4.200 - Arabidopsis thaliana
 emb|CAB45329.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79727.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 457

 Score =  271 bits (688), Expect = 3e-71
 Identities = 47/282 (16%), Positives = 93/282 (32%), Gaps = 33/282 (11%)

Query: 48  QELMISKKGKFWISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVF 107
           +       G       L V     +  +    D   +        K  N+     P ++ 
Sbjct: 5   KPGRSGFSGYILYKLSLTVLIVLSVAVTANGSDSPSSYVRRPQPPKKLNK-----PVVLL 59

Query: 108 MVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGT 167
           +  D FR  +   +          I++ +          PT+T P   +  TG  P+   
Sbjct: 60  ISCDGFRFGYQFKT--ETPNIDLLISRGTEAKTGLIPVFPTMTFPNHYSIATGLYPASHG 117

Query: 168 VLTNLATAEM---------------KTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKF 212
           ++ N  T  +                   W++ + +      +F       +   S+   
Sbjct: 118 IIMNKFTDPVSGELFNRNLNPKWWLGEPLWVTAVNQGLMAATYFWPG--ADVHKGSWNCP 175

Query: 213 EGVTSFFVSDYTDVDNNVTRHLDTELSNTN----HSWDALILHYLGLDHIGHSLGGSSSK 268
           +G          +V   +   +DT L+  +       D + L++   D  GH  G    +
Sbjct: 176 KGFC----KAPYNVSVPLEERVDTILNYFDLPEREIPDFMALYFDEPDIQGHEYGPDDPR 231

Query: 269 IPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAA 310
           + E + ++D +IGRI   L+       + ++I+ GDHGM   
Sbjct: 232 VTEAVSKVDKMIGRIIMGLEKRKVF-SDVHVILLGDHGMVTN 272
>gb|AAK25979.1|AF360269_1 (AF360269) putative nucleotide pyrophosphatase [Arabidopsis
           thaliana]
          Length = 456

 Score =  265 bits (672), Expect = 2e-69
 Identities = 61/283 (21%), Positives = 110/283 (38%), Gaps = 36/283 (12%)

Query: 47  LQELMISKKGKFWISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLV 106
           L   + S    F+I   +   A A +      LD  P+     + FK  N+     P ++
Sbjct: 4   LSNFLSSSFLIFFIVATIA--AAAAVNAGTKGLDSRPSKTRRPWPFKKLNK-----PVVL 56

Query: 107 FMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFG 166
            +  D FR  +   +          I+  +          PT+T P   +  TG  P++ 
Sbjct: 57  MISCDGFRFGYQFKTD--TPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATGLYPAYH 114

Query: 167 TVLTNLATAEM---------------KTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEK 211
            ++ N  T  +                   W++ + +  K V +F   +   +L  S+  
Sbjct: 115 GIIMNKFTDPVTGEVFNKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPSS--EVLKSSWTC 172

Query: 212 FEGVTSFFVSDYTDVDNNVTRHLDTELSNTNHS----WDALILHYLGLDHIGHSLGGSSS 267
            EG    F     ++   +   +D+ LS+ +H      D L+L++   D  GH+ G    
Sbjct: 173 PEGYCPHF-----NLSVPLEERVDSVLSHFDHLEDEVPDLLMLYFDEPDQSGHNYGPDDP 227

Query: 268 KIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDHGMTAA 310
           ++   +  +D +IGR+ K LK     D E ++I+ GDHGM   
Sbjct: 228 RVTTAVSRVDKMIGRVIKGLKQREIFD-EVHVILLGDHGMVTN 269
>ref|NP_194699.1| (NM_119115) nucleotide pyrophosphatase -like protein [Arabidopsis
           thaliana]
 pir||T09933 nucleotide pyrophosphatase homolog T16L4.210 - Arabidopsis thaliana
 emb|CAB45330.1| (AL079344) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
 emb|CAB79728.1| (AL161575) nucleotide pyrophosphatase-like protein [Arabidopsis
           thaliana]
          Length = 461

 Score =  262 bits (665), Expect = 1e-68
 Identities = 59/270 (21%), Positives = 106/270 (38%), Gaps = 34/270 (12%)

Query: 60  ISRVLVVCACALLVYSFVALDITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLT 119
           I  V  + A A +      LD  P+     + FK  N+     P ++ +  D FR  +  
Sbjct: 20  IFIVATIAAAAAVNAGTKGLDSRPSKTRRPWPFKKLNK-----PVVLMISCDGFRFGYQF 74

Query: 120 SSKSPMSFTKSEITKKSAKLFDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM-- 177
            +          I+  +          PT+T P   +  TG  P++  ++ N  T  +  
Sbjct: 75  KTD--TPNIDLLISGGTEAKHGLIPVFPTMTFPNHYSIATGLYPAYHGIIMNKFTDPVTG 132

Query: 178 -------------KTANWISRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYT 224
                            W++ + +  K V +F   +   +L  S+   EG    F     
Sbjct: 133 EVFNKGLQPKWWLGEPLWVTAVNQGLKAVTYFWPGS--EVLKSSWTCPEGYCPHF----- 185

Query: 225 DVDNNVTRHLDTELSNTNHS----WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVI 280
           ++   +   +D+ LS+ +H      D L+L++   D  GH+ G    ++   +  +D +I
Sbjct: 186 NLSVPLEERVDSVLSHFDHLEDEVPDLLMLYFDEPDQSGHNYGPDDPRVTTAVSRVDKMI 245

Query: 281 GRIHKYLKSSTSVDQESYLIVCGDHGMTAA 310
           GR+ K LK     D E ++I+ GDHGM   
Sbjct: 246 GRVIKGLKQREIFD-EVHVILLGDHGMVTN 274
>pir||T03293 nucleotide pyrophosphatase homolog - rice
 gb|AAA67067.1| (U25430) nucleotide pyrophosphatase precursor [Oryza sativa]
 gb|AAF65458.1|AF245483_1 (AF245483) OSE4 [Oryza sativa]
 dbj|BAB56086.1| (AP003244) nucleotide pyrophosphatase homolog [Oryza sativa]
          Length = 479

 Score =  255 bits (647), Expect = 2e-66
 Identities = 45/308 (14%), Positives = 91/308 (28%), Gaps = 35/308 (11%)

Query: 20  EAEEEDTKRKSIKFLRTHNHHQSENKELQELMISKKGKFWISRVLVVCACALLVYSFVAL 79
            A +          L       +          S   +  +     +      +   +  
Sbjct: 12  AAGDSPPPT---ALLLPRTTTTTAGAAPAPRRSSASSRLHLLLTAALAVATSYLLLILPR 68

Query: 80  DITPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKL 139
             TP             Q     P ++ +  D FR  +   +          I   ++  
Sbjct: 69  --TPLSAAPAPAAAARAQVKLEKPVVILISSDGFRFGYQHKA--ATPHIHRLIGNGTSAA 124

Query: 140 FDAYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEM----------------KTANWI 183
                  PT+T P   +  TG  PS   ++ N     +                    W+
Sbjct: 125 TGLVPIFPTLTFPNHYSIATGLYPSSHGIINNYFPDPISGDYFTMSSHEPKWWLGEPLWV 184

Query: 184 SRIQKIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSNT-- 241
           +   +  +   +F   + ++    S++  +           +        +D  L     
Sbjct: 185 TAADQGIQAATYFWPGSEVK--KGSWDCPDKYCRH-----YNGSVPFEERVDAILGYFDL 237

Query: 242 --NHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYL 299
             +     L L++   DH GH +G     I E +  +D++IGR+   L+     + +  +
Sbjct: 238 PSDEMPQFLTLYFEDPDHQGHQVGPDDPAITEAVVRIDEMIGRLIAGLEERGVFE-DVNV 296

Query: 300 IVCGDHGM 307
           I+ GDHGM
Sbjct: 297 ILVGDHGM 304
>dbj|BAA02053.1| (D12485) The first in-frame ATG codon is located at nucleotides
           17-19, followed by a second ATG codon 52 codons
           downstream. And the second ATG codon is potential
           initiation point for translation of NPPase. [Homo
           sapiens]
          Length = 930

 Score =  252 bits (639), Expect = 2e-65
 Identities = 41/248 (16%), Positives = 77/248 (30%), Gaps = 35/248 (14%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            E   +        +P  +   +D FR  +L +    +          +    +     P
Sbjct: 200 CESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTK-NMRPVYP 258

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P   + +TG  P    ++ N                             W++   +
Sbjct: 259 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQ 318

Query: 189 IGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNHS 244
             K   FF   + + +    F     +         +        +   L       +  
Sbjct: 319 GLKSGTFFWPGSDVEI-NGIFPDIYKM--------YNGSVPFEERILAVLQWLQLPKDER 369

Query: 245 WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGD 304
                L+    D  GHS G  SS++ + L+ +D ++G +   LK   ++ +   LI+  D
Sbjct: 370 PHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE-LNLHRCLNLILISD 428

Query: 305 HGMTAAGS 312
           HGM   GS
Sbjct: 429 HGM-EQGS 435
>pir||A39216 plasma cell membrane glycoprotein PC-1 - human
 gb|AAF36094.1| (AF110304) PDNP1 [Homo sapiens]
 emb|CAC39442.1| (AJ242020) plasma cell membrane glycoprotein [Homo sapiens]
          Length = 925

 Score =  252 bits (638), Expect = 2e-65
 Identities = 41/248 (16%), Positives = 77/248 (30%), Gaps = 35/248 (14%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            E   +        +P  +   +D FR  +L +    +          +    +     P
Sbjct: 195 CESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTK-NMRPVYP 253

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P   + +TG  P    ++ N                             W++   +
Sbjct: 254 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQ 313

Query: 189 IGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNHS 244
             K   FF   + + +    F     +         +        +   L       +  
Sbjct: 314 GLKSGTFFWPGSDVEI-NGIFPDIYKM--------YNGSVPFEERILAVLQWLQLPKDER 364

Query: 245 WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGD 304
                L+    D  GHS G  SS++ + L+ +D ++G +   LK   ++ +   LI+  D
Sbjct: 365 PHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE-LNLHRCLNLILISD 423

Query: 305 HGMTAAGS 312
           HGM   GS
Sbjct: 424 HGM-EQGS 430
>ref|NP_445987.1| (NM_053535) ectonucleotide pyrophosphatase/phosphodiesterase 1
           [Rattus norvegicus]
 gb|AAK69654.1|AF340186_1 (AF340186) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  250 bits (634), Expect = 6e-65
 Identities = 41/248 (16%), Positives = 76/248 (30%), Gaps = 35/248 (14%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            E            SP  +   +D FR  +L +    +          +    +     P
Sbjct: 177 CETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTK-NMRPVYP 235

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P   + +TG  P    ++ N                             W++   +
Sbjct: 236 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQ 295

Query: 189 IGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNHS 244
             +   +F   + + +          V         +        +   L      +   
Sbjct: 296 EVRSGTYFWPGSDVEI-DGILPDIYKV--------YNGSVPFEERILAVLEWLQLPSYER 346

Query: 245 WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGD 304
                L+    D  GHS G  SS++ + L+++D ++G +   LK    +D+   LI+  D
Sbjct: 347 PHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKD-LGLDKCLNLILISD 405

Query: 305 HGMTAAGS 312
           HGM   GS
Sbjct: 406 HGM-EQGS 412
>ref|NP_005012.1| (NM_005021) ectonucleotide pyrophosphatase/phosphodiesterase 3;
           phosphodiesterase I/nucleotide pyrophosphatase 3;
           phosphodiesterase-I beta; gp130RB13-6; bovine intestinal
           phosphodiesterase [Homo sapiens]
 gb|AAC51813.1| (AF005632) phosphodiesterase I/nucleotide pyrophosphatase beta
           [Homo sapiens]
          Length = 875

 Score =  250 bits (634), Expect = 6e-65
 Identities = 38/249 (15%), Positives = 78/249 (31%), Gaps = 40/249 (16%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            +   +    E    P ++   +D FR  +L +  + M       T      +   A  P
Sbjct: 144 CDTAQQSQCPEGFDLPPVILFSMDGFRAEYLYTWDTLMPNINKLKTCGIHSKY-MRAMYP 202

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAEM-------------------KTANWISRIQK 188
           T T P     +TG  P    ++ N                             W++ + +
Sbjct: 203 TKTFPNHYTIVTGLYPESHGIIDNNMYDVNLNKNFSLSSKEQNNPAWWHGQPMWLTAMYQ 262

Query: 189 IGKKVHFFGDDTWIRL---LPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSNTN--- 242
             K   +F   + + +    P  +               +        + T L   +   
Sbjct: 263 GLKAATYFWPGSEVAINGSFPSIYM------------PYNGSVPFEERISTLLKWLDLPK 310

Query: 243 -HSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIV 301
                   +++   D  GH+ G  S+++ + L+ +D   G + + LK   ++     +I+
Sbjct: 311 AERPRFYTMYFEEPDSSGHAGGPVSARVIKALQVVDHAFGMLMEGLKQR-NLHNCVNIIL 369

Query: 302 CGDHGMTAA 310
             DHGM   
Sbjct: 370 LADHGMDQT 378
>gb|AAL26912.1| (AF320054) ecto-nucleotide pyrophosphatase [Rattus norvegicus]
          Length = 906

 Score =  250 bits (634), Expect = 6e-65
 Identities = 41/248 (16%), Positives = 76/248 (30%), Gaps = 35/248 (14%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            E            SP  +   +D FR  +L +    +          +    +     P
Sbjct: 177 CETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTK-NMRPVYP 235

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P   + +TG  P    ++ N                             W++   +
Sbjct: 236 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQ 295

Query: 189 IGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNHS 244
             +   +F   + + +          V         +        +   L      +   
Sbjct: 296 EVRSGTYFWPGSDVEI-DGILPDIYKV--------YNGSVPFEERILAVLEWLQLPSYER 346

Query: 245 WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGD 304
                L+    D  GHS G  SS++ + L+++D ++G +   LK    +D+   LI+  D
Sbjct: 347 PHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKD-LGLDKCLNLILISD 405

Query: 305 HGMTAAGS 312
           HGM   GS
Sbjct: 406 HGM-EQGS 412
>gb|AAK69653.1|AF340185_1 (AF340185) ecto-nucleotide pyrophosphatase/phosphodiesterase-1
           [Rattus norvegicus]
          Length = 906

 Score =  250 bits (633), Expect = 7e-65
 Identities = 41/248 (16%), Positives = 76/248 (30%), Gaps = 35/248 (14%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            E            SP  +   +D FR  +L +    +          +    +     P
Sbjct: 177 CETIDAPQCPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTK-NMRPVYP 235

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P   + +TG  P    ++ N                             W++   +
Sbjct: 236 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANHQ 295

Query: 189 IGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNHS 244
             +   +F   + + +          V         +        +   L      +   
Sbjct: 296 EVRSGTYFWPGSDVEI-DGILPDIYKV--------YNGSVPFEERILAVLEWLQLPSYER 346

Query: 245 WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGD 304
                L+    D  GHS G  SS++ + L+++D ++G +   LK    +D+   LI+  D
Sbjct: 347 PHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDHIVGMLMDGLKD-LGLDKCLNLILISD 405

Query: 305 HGMTAAGS 312
           HGM   GS
Sbjct: 406 HGM-EQGS 412
>ref|NP_006199.1| (NM_006208) ectonucleotide pyrophosphatase/phosphodiesterase 1;
           phosphodiesterase I/nucleotide pyrophosphatase 1
           (homologous to mouse Ly-41 antigen); plasma-cell
           membrane glycoprotein [Homo sapiens]
 sp|P22413|PC1_HUMAN ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (PLASMA-CELL
           MEMBRANE GLYCOPROTEIN PC-1) [INCLUDES: ALKALINE
           PHOSPHODIESTERASE I ; NUCLEOTIDE PYROPHOSPHATASE
           (NPPASE)]
 gb|AAA63237.1| (M57736) plasma cell membrane glycoprotein PC-1 [Homo sapiens]
 dbj|BAA02054.1| (D12485) NPPase [Homo sapiens]
          Length = 873

 Score =  250 bits (633), Expect = 8e-65
 Identities = 41/248 (16%), Positives = 77/248 (30%), Gaps = 35/248 (14%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            E   +        +P  +   +D FR  +L +    +          +    +     P
Sbjct: 143 CESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTK-NMRPVYP 201

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P   + +TG  P    ++ N                             W++   +
Sbjct: 202 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQ 261

Query: 189 IGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNHS 244
             K   FF   + + +    F     +         +        +   L       +  
Sbjct: 262 GLKSGTFFWPGSDVEI-NGIFPDIYKM--------YNGSVPFEERILAVLQWLQLPKDER 312

Query: 245 WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGD 304
                L+    D  GHS G  SS++ + L+ +D ++G +   LK   ++ +   LI+  D
Sbjct: 313 PHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE-LNLHRCLNLILISD 371

Query: 305 HGMTAAGS 312
           HGM   GS
Sbjct: 372 HGM-EQGS 378
>ref|NP_032839.2| (NM_008813) phosphodiesterase I/nucleotide pyrophosphatase 1; 1
           ectonucleotide pyrophosphatase/phosphodiesterase 1 [Mus
           musculus]
 gb|AAA39893.2| (J02700) ecto-nucleotide pyrophosphatase/phosphodiesterase-1 [Mus
           musculus domesticus]
          Length = 905

 Score =  249 bits (632), Expect = 1e-64
 Identities = 43/249 (17%), Positives = 78/249 (31%), Gaps = 35/249 (14%)

Query: 87  TEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARM 146
           T E            SP  +   +D FR  +L +    +          +    +     
Sbjct: 176 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTK-NMRPMY 234

Query: 147 PTVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQ 187
           PT T P   + +TG  P    ++ N                             W++   
Sbjct: 235 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANH 294

Query: 188 KIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNH 243
           +  K   +F   + + +          V         +        +   L      ++ 
Sbjct: 295 QEVKSGTYFWPGSDVEI-DGILPDIYKV--------YNGSVPFEERILAVLEWLQLPSHE 345

Query: 244 SWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCG 303
                 L+    D  GHS G  SS++ + L+++D ++G +   LK    +D+   LI+  
Sbjct: 346 RPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD-LGLDKCLNLILIS 404

Query: 304 DHGMTAAGS 312
           DHGM   GS
Sbjct: 405 DHGM-EQGS 412
>gb|AAK84174.1|AF339910_1 (AF339910) ectonucleotide pyrophosphatase/phosphodiesterase 1
           allotype b [Mus musculus]
          Length = 906

 Score =  249 bits (632), Expect = 1e-64
 Identities = 43/249 (17%), Positives = 78/249 (31%), Gaps = 35/249 (14%)

Query: 87  TEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARM 146
           T E            SP  +   +D FR  +L +    +          +    +     
Sbjct: 176 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTK-NMRPMY 234

Query: 147 PTVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQ 187
           PT T P   + +TG  P    ++ N                             W++   
Sbjct: 235 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANH 294

Query: 188 KIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNH 243
           +  K   +F   + + +          V         +        +   L      ++ 
Sbjct: 295 QEVKSGTYFWPGSDVEI-DGILPDIYKV--------YNGSVPFEERILAVLEWLQLPSHE 345

Query: 244 SWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCG 303
                 L+    D  GHS G  SS++ + L+++D ++G +   LK    +D+   LI+  
Sbjct: 346 RPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD-LGLDKCLNLILIS 404

Query: 304 DHGMTAAGS 312
           DHGM   GS
Sbjct: 405 DHGM-EQGS 412
>pir||A27410 plasma cell membrane glycoprotein PC-1 - mouse
          Length = 905

 Score =  249 bits (632), Expect = 1e-64
 Identities = 43/249 (17%), Positives = 78/249 (31%), Gaps = 35/249 (14%)

Query: 87  TEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARM 146
           T E            SP  +   +D FR  +L +    +          +    +     
Sbjct: 176 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTK-NMRPMY 234

Query: 147 PTVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQ 187
           PT T P   + +TG  P    ++ N                             W++   
Sbjct: 235 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANH 294

Query: 188 KIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNH 243
           +  K   +F   + + +          V         +        +   L      ++ 
Sbjct: 295 QEVKSGTYFWPGSDVEI-DGILPDIYKV--------YNGSVPFEERILAVLEWLQLPSHE 345

Query: 244 SWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCG 303
                 L+    D  GHS G  SS++ + L+++D ++G +   LK    +D+   LI+  
Sbjct: 346 RPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD-LGLDKCLNLILIS 404

Query: 304 DHGMTAAGS 312
           DHGM   GS
Sbjct: 405 DHGM-EQGS 412
>emb|CAB99365.1| (AL117378) dJ131F15.2 (phosphodiesterase I/nucleotide
           pyrophosphatase 1 (homologous to mouse Ly-41 antigen)
           (PC1, NPPS)) [Homo sapiens]
          Length = 845

 Score =  249 bits (630), Expect = 2e-64
 Identities = 41/248 (16%), Positives = 77/248 (30%), Gaps = 35/248 (14%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
            E   +        +P  +   +D FR  +L +    +          +    +     P
Sbjct: 115 CESINEPQCPAGFETPPTLLFSLDGFRAEYLHTWGGLLPVISKLKKCGTYTK-NMRPVYP 173

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P   + +TG  P    ++ N                             W++   +
Sbjct: 174 TKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPEWYKGEPIWVTAKYQ 233

Query: 189 IGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNHS 244
             K   FF   + + +    F     +         +        +   L       +  
Sbjct: 234 GLKSGTFFWPGSDVEI-NGIFPDIYKM--------YNGSVPFEERILAVLQWLQLPKDER 284

Query: 245 WDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGD 304
                L+    D  GHS G  SS++ + L+ +D ++G +   LK   ++ +   LI+  D
Sbjct: 285 PHFYTLYLEEPDSSGHSYGPVSSEVIKALQRVDGMVGMLMDGLKE-LNLHRCLNLILISD 343

Query: 305 HGMTAAGS 312
           HGM   GS
Sbjct: 344 HGM-EQGS 350
>sp|P06802|PC1_MOUSE Ectonucleotide pyrophosphatase/phosphodiesterase 1 (Plasma-cell
           membrane glycoprotein PC-1) [Includes: Alkaline
           phosphodiesterase I ; Nucleotide pyrophosphatase
           (NPPASE)]
          Length = 871

 Score =  248 bits (628), Expect = 3e-64
 Identities = 43/249 (17%), Positives = 78/249 (31%), Gaps = 35/249 (14%)

Query: 87  TEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARM 146
           T E            SP  +   +D FR  +L +    +          +    +     
Sbjct: 142 TCESIDTPECPAEFESPPTLLFSLDGFRAEYLHTWGGLLPVISKLKNCGTYTK-NMRPMY 200

Query: 147 PTVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQ 187
           PT T P   + +TG  P    ++ N                             W++   
Sbjct: 201 PTKTFPNHYSIVTGLYPESHGIIDNKMYDPKMNASFSLKSKEKFNPLWYKGQPIWVTANH 260

Query: 188 KIGKKVHFFGDDTWIRLLPRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSN----TNH 243
           +  K   +F   + + +          V         +        +   L      ++ 
Sbjct: 261 QEVKSGTYFWPGSDVEI-DGILPDIYKV--------YNGSVPFEERILAVLEWLQLPSHE 311

Query: 244 SWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCG 303
                 L+    D  GHS G  SS++ + L+++D ++G +   LK    +D+   LI+  
Sbjct: 312 RPHFYTLYLEEPDSSGHSHGPVSSEVIKALQKVDRLVGMLMDGLKD-LGLDKCLNLILIS 370

Query: 304 DHGMTAAGS 312
           DHGM   GS
Sbjct: 371 DHGM-EQGS 378
>dbj|BAA06333.1| (D30649) phosphodiesterase I [Rattus norvegicus]
          Length = 876

 Score =  239 bits (606), Expect = 1e-61
 Identities = 38/248 (15%), Positives = 74/248 (29%), Gaps = 38/248 (15%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
                +    E    P ++   +D FR  +L +  + +       T      +   A  P
Sbjct: 145 CASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKTCGLHSKY-MRAVYP 203

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P     +TG  P    ++ N                             W++ + +
Sbjct: 204 TKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQ 263

Query: 189 IGKKVHFFGDDTWIRL---LPRS---FEKFEGVTSFFVSDYTDVDNNVTRHLDTELSNTN 242
             K   ++   + + +    P     +       S   +    +D               
Sbjct: 264 GLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLP-----------KA 312

Query: 243 HSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVC 302
                  ++    D  GH  G  S+ + + L+ +DD  G + + LK   ++     +IV 
Sbjct: 313 ERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQR-NLHNCVNIIVL 371

Query: 303 GDHGMTAA 310
            DHGM   
Sbjct: 372 ADHGMDQT 379
>ref|NP_062243.1| (NM_019370) alkaline phosphodiesterase [Rattus norvegicus]
 gb|AAB61535.1| (U78787) alkaline phosphodiesterase [Rattus norvegicus]
          Length = 875

 Score =  239 bits (606), Expect = 1e-61
 Identities = 38/248 (15%), Positives = 74/248 (29%), Gaps = 38/248 (15%)

Query: 88  EEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFDAYARMP 147
                +    E    P ++   +D FR  +L +  + +       T      +   A  P
Sbjct: 145 CASSQEPQCPEGFDQPPVILFSMDGFRAEYLQTWSTLLPNINKLKTCGLHSKY-MRAVYP 203

Query: 148 TVTLPRITAYLTGTLPSFGTVLTNLATAE-------------------MKTANWISRIQK 188
           T T P     +TG  P    ++ N                             W++ + +
Sbjct: 204 TKTFPNHYTIVTGLYPESHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPIWLTAMYQ 263

Query: 189 IGKKVHFFGDDTWIRL---LPRS---FEKFEGVTSFFVSDYTDVDNNVTRHLDTELSNTN 242
             K   ++   + + +    P     +       S   +    +D               
Sbjct: 264 GLKAASYYWPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLP-----------KA 312

Query: 243 HSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVC 302
                  ++    D  GH  G  S+ + + L+ +DD  G + + LK   ++     +IV 
Sbjct: 313 ERPSFYTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQR-NLHNCVNIIVL 371

Query: 303 GDHGMTAA 310
            DHGM   
Sbjct: 372 ADHGMDQT 379
>ref|NP_105837.1| (NC_002678) hypothetical protein [Mesorhizobium loti]
 dbj|BAB51623.1| (AP003005) hypothetical protein [Mesorhizobium loti]
          Length = 298

 Score =  236 bits (598), Expect = 1e-60
 Identities = 58/310 (18%), Positives = 110/310 (34%), Gaps = 50/310 (16%)

Query: 82  TPTPPTEEFGFKDGNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLFD 141
            P    +  G     +          +++D        + +  M   +  +    A+++ 
Sbjct: 8   VPVSTVKPDGAAMALKSKLLL-----IILDGVPY---RNWRRLMGNLEGWVQSGEARVWK 59

Query: 142 AYARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTANWISRIQKIGKKVHFFGDDTW 201
             + +P+ +     +  TG  P    +L+N     +   +  S + K G K        W
Sbjct: 60  MRSVLPSTSACCYASIHTGVSPQVHGILSNENRFRVGQPDIFSEVSKAGGKTGAVTHSYW 119

Query: 202 IRLL------------------PRSFEKFEGVTSFFVSDY---TDVDNNVTRHLDTELSN 240
                                 P +  +F  +T +   +    +DVD   T  + T    
Sbjct: 120 SEFFRSYPFDLVEDMEYDEPGGPITHGRFHTMTGYNARNQMTPSDVDLFATLTMLT---- 175

Query: 241 TNHSWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLI 300
             H  D  ILH   LD +GH  G    ++   +  MD   G +  +L    +   E   +
Sbjct: 176 KRHGIDYGILHTCTLDSMGHRFGNDCHEMDHAVYAMD---GMLAAFLPGWIAAGYEV--M 230

Query: 301 VCGDHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSST 360
           V  DHG T  G HGG   D+      ++ FG+ +     G + D+L     ++Q+ ++ T
Sbjct: 231 VTADHGQTDRGHHGGH--DDEMQDFALYYFGQGQ-----GPETDTL-----LDQLQLAPT 278

Query: 361 IFDVFNMPIP 370
           +     +P+P
Sbjct: 279 VLSRLGVPVP 288
>ref|XP_056208.1| (XM_056208) hypothetical protein MGC3079 [Homo sapiens]
 gb|AAH13987.1|AAH13987 (BC013987) Similar to hypothetical protein MGC3079 [Homo sapiens]
          Length = 454

 Score =  236 bits (597), Expect = 1e-60
 Identities = 54/233 (23%), Positives = 93/233 (39%), Gaps = 31/233 (13%)

Query: 244 SWDALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCG 303
            WD LI H+LG+DH GH  G    ++ +KL +MD VI  + + L+       ++ L+V G
Sbjct: 5   EWDVLIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQGLVERLE------NDTLLVVAG 58

Query: 304 DHGMTAAGSHGGASPDETRVPVVIWKFGREEGNKNYGNQDDSLKQPPRIEQIDVSSTIFD 363
           DHGMT  G HGG S  E    + ++                  ++P  I Q+ +  T+  
Sbjct: 59  DHGMTTNGDHGGDSELEVSAALFLYS-------PTAVFPSTPPEEPEVIPQVSLVPTLAL 111

Query: 364 VFNMPIPIESYGISLINYFSDDEEE--------YFEKQHNQFRR---IVQAKHLAISDI- 411
           +  +PIP  + G  +   FS  E+              H   ++    +     A  D+ 
Sbjct: 112 LLGLPIPFGNIGEVMAELFSGGEDSQPHSSALAQASALHLNAQQVSRFLHTYSAATQDLQ 171

Query: 412 -CDENCDYSDKFIKSALKKWFLT----VQSELIGSASEVPNKSLGVCVFLLLV 459
             + +   +     SA  +W L      ++ L    +E+     G    + + 
Sbjct: 172 AKELHQLQNLFSKASADYQWLLQSPKGAEATLPTVIAELQQFLRG-ARAMCIE 223
 Score = 81.6 bits (200), Expect = 5e-14
 Identities = 15/73 (20%), Positives = 26/73 (35%), Gaps = 3/73 (4%)

Query: 675 GSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQ---PILVGLQLMLYTFSGPILF 731
               +  +   +F+ TG+      +   +A+VG          L  L +   TF+  +LF
Sbjct: 256 AVSAWALMATQTFYSTGHQPVFPAIHWHAAFVGFPEGHGSCTWLPALLVGANTFASHLLF 315

Query: 732 LCGCNASSCTSLL 744
             GC        L
Sbjct: 316 AVGCPLLLLWPFL 328
 Score = 63.7 bits (154), Expect = 1e-08
 Identities = 11/50 (22%), Positives = 21/50 (42%), Gaps = 3/50 (6%)

Query: 742 SLLNHLFSYRISS---MCTSLICLYIFQNHLFIWSVYSPKVVYDMAHVIF 788
           +LL     Y       +    +   I + HL +W V++PK +++    I 
Sbjct: 373 ALLQLGLKYLFILGIQILACALAASILRRHLMVWKVFAPKFIFEAVGFIV 422
>ref|NP_013069.1| (NC_001144) Glycosylphosphatidylinositol (GPI) biosynthesis; Gpi13p
           [Saccharomyces cerevisiae]
 pir||S64782 probable membrane protein YLL031c - yeast (Saccharomyces
           cerevisiae)
 emb|CAA97480.1| (Z73136) ORF YLL031c [Saccharomyces cerevisiae]
          Length = 1017

 Score =  235 bits (596), Expect = 2e-60
 Identities = 94/373 (25%), Positives = 149/373 (39%), Gaps = 32/373 (8%)

Query: 25  DTKRKSIKFLRTHNHHQSENKELQEL--MISKKGKFWISRVLVVCACALLVYSFVALDIT 82
           D K      L + N    E    +       K  KF+I  ++ +     +  +F      
Sbjct: 2   DEKTIKKSILSSSN---DEKIIYKSRIKKFQKNHKFYIILLVFIAILQFISIAFFTRGFL 58

Query: 83  PTPPTEEFGFKD--GNQESSSSPRLVFMVIDAFRLSFLTSSKSPMSFTKSEITKKSAKLF 140
            +    +        ++      + V +VIDA R  F        S            L+
Sbjct: 59  LSRHVLDNISSQNETSKLPPRFNKAVILVIDALRFDFAIPVNESHSNYNLNYHNNILSLY 118

Query: 141 DAY--------------ARMPTVTLPRITAYLTGTLPSFGTVLTNLATAEMKTANWISRI 186
           D++              A  PT TL R+    TG+LP+F    +N     ++  N++ ++
Sbjct: 119 DSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDAGSNFDGTVIEEDNFLKQL 178

Query: 187 QKIGKKVHFFGDDTWIRLL-PRSFEKFEGVTSFFVSDYTDVDNNVTRHLDTELSNTNHSW 245
               K V F GDDTW+ L  P        + S  V D   VDN V  +    L   +  W
Sbjct: 179 HLANKTVKFAGDDTWMALFHPFLSNDSFPLESLNVWDLDTVDNGVMDYFHDHLQQ-DKEW 237

Query: 246 DALILHYLGLDHIGHSLGGSSSKIPEKLKEMDDVIGRIHKYLKSSTSVDQESYLIVCGDH 305
           D +I H LG+DH+GH  G     + EK  ++D  I  I K      S+D ++ L++ GDH
Sbjct: 238 DVMIGHMLGIDHVGHKYGPDHFTMREKQIQVDQFIDWILK------SIDDDTLLVILGDH 291

Query: 306 GMTAAGSHGGASPDETRVPVVIWKFGRE--EGNKNYGNQDDSLKQPPR-IEQIDVSSTIF 362
           GM   G+HGG S DE    + ++    +     +      D+L    R + QID+ S++ 
Sbjct: 292 GMDHTGNHGGDSIDELESTLFLYSKKPDMWRLKETSNYNIDNLGHDYRSVRQIDLVSSLA 351

Query: 363 DVFNMPIPIESYG 375
            +   PIP  + G
Sbjct: 352 LLMGQPIPFNNLG 364
>gb|AAL39196.1| (AY069051) GH05767p [Drosophila melanogaster]
          Length = 608

 Score =  205 bits (518), Expect = 2e-51
 Identities = 82/393 (20%), Positives = 143/393 (35%), Gaps = 89/393 (22%)

Query: 481 LINITYFASSLIEEEHEIWYYLGSTVVAIRALRNFK------------------------ 516
           +  +T  +SS IE E+  WYYLG+T++ + A R  +                        
Sbjct: 215 IRTLTLGSSSFIEFEYNTWYYLGNTLILLTAFRTLRWRITKTNVELNGRHLYTIASTCLW 274

Query: 517 ---------------IWNKTEVKS-----IFFLAFLHRIACSYTQSTRRRW--------I 548
                           +            IF +  L   A    + ++            
Sbjct: 275 QMRKVLVVLMLLTLMRYIHRLQAIRSTVVIFSMLLL--WAR-LHRHSQLPQSLASGAALF 331

Query: 549 MDSSLLPPSIFSDTLDFQPNNLNT-ILNEYPIIVILTCSLFWMYGYKQSKFHIILPMVSH 607
           M       +         P+++   ++    +I     +L  M GY+ +     LP    
Sbjct: 332 MVYCFRGLNG-QVLFFDVPSHMAAKLMVPTLVIFWCCLALVLMLGYRAA-----LPQAHS 385

Query: 608 FLRLFELTQFNEVLMHFIRLSILPISYSTGSVLAGCLPLLLAIVPVSQILLLLVIY--NM 665
           F ++        + +    L+   +  +    +   L L + +V + Q   L  +Y  + 
Sbjct: 386 FGKVPPT--GALLQLLQTNLTSSLLLAALLQRVHNILLLPVLLVALQQTYKLCDVYGTSA 443

Query: 666 GKLFSK--LNLGSVEFVTLCMSSFFYTGNSNSLSTLSLTSAYVGLSSYQPILVGLQLMLY 723
            K   +       +  + L    FFY GNSNSLST+ LT  Y+G ++Y P +V + + L 
Sbjct: 444 RKFSVRLVHVYKIIMTIFLARMFFFYQGNSNSLSTIDLTPGYIGQTNYNPSIVAIFVTLN 503

Query: 724 TFSGPILFLC------------------GCNASSCTS--LLNHLFSYRISSMCTSLICLY 763
           T+S  I                           S  +  L+  L++  I       +CL 
Sbjct: 504 TYSADIHAFLYLVVHTLRSDLRSVGIMQLHPPYSIAADSLIAPLYAALIMLPAAFYLCLL 563

Query: 764 I-FQNHLFIWSVYSPKVVYDMAHVIFFGLIGLL 795
           + F+ HLFI+SV+SPKV+YD   V+ F L+ L+
Sbjct: 564 VGFRYHLFIYSVFSPKVLYDCYTVLVFYLVFLV 596
CPU time:   223.06 user secs.	    3.00 sys. secs	  226.06 total secs.

  Database: nr
    Posted date:  Apr 21, 2002  2:19 PM
  Number of letters in database: 277,845,442
  Number of sequences in database:  887,402
  
Lambda     K      H
   0.317    0.181    0.484 

Gapped
Lambda     K      H
   0.270   0.0635    0.230 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 570581405
Number of Sequences: 887402
Number of extensions: 33075124
Number of successful extensions: 125485
Number of sequences better than 10.0: 1159
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 1036
Number of HSP's that attempted gapping in prelim test: 123567
Number of HSP's gapped (non-prelim): 2166
length of query: 795
length of database: 277,845,442
effective HSP length: 57
effective length of query: 738
effective length of database: 227,263,528
effective search space: 167720483664
effective search space used: 167720483664
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.8 bits)
X3: 64 (24.9 bits)
S1: 41 (21.2 bits)
S2: 77 (34.0 bits)